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Linda Siracusa

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Richard C Crist; Jacquelyn J Roth; Michael P Lisanti; Linda D Siracusa; Arthur M Buchberg
Identification of Mom12 and Mom13, two novel modifier loci of Apc (Min) -mediated intestinal tumorigenesis.
Richard C Crist; Jacquelyn J Roth; Amy A Baran; Benjamin J McEntee; Linda D Siracusa; Arthur M Buchberg
The armadillo repeat domain of Apc suppresses intestinal tumorigenesis.
Bruce Boman; Levy Kopelovich; Linda D Siracusa; Tao Zhang; Kim Henderson; Zenobia Cofer; Arthur M Buchberg; Jeremy Z Fields; Tomas Otevrel
A Tcf4-GFP reporter mouse model for monitoring effects of Apc mutations during intestinal tumorigenesis.

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All Publications

2011: Richard C Crist; Jacquelyn J Roth; Michael P Lisanti; Linda D Siracusa; Arthur M Buchberg
Identification of Mom12 and Mom13, two novel modifier loci of Apc (Min) -mediated intestinal tumorigenesis.
Cell cycle (Georgetown, Tex.) 2011;10(7):1092-9.
2010: Richard C Crist; Jacquelyn J Roth; Amy A Baran; Benjamin J McEntee; Linda D Siracusa; Arthur M Buchberg
The armadillo repeat domain of Apc suppresses intestinal tumorigenesis.
Mammalian genome : official journal of the International Mammalian Genome Society 2010;21(9-10):450-7.
2009: Bruce Boman; Levy Kopelovich; Linda D Siracusa; Tao Zhang; Kim Henderson; Zenobia Cofer; Arthur M Buchberg; Jeremy Z Fields; Tomas Otevrel
A Tcf4-GFP reporter mouse model for monitoring effects of Apc mutations during intestinal tumorigenesis.
Molecular carcinogenesis 2009;48(9):821-31.
2008: Linda D Siracusa; Arthur M Buchberg
The noncoding RNAs: a genomic symphony of transcripts.
Mammalian genome : official journal of the International Mammalian Genome Society 2008;19(7-8):449-53.
2007: Peng Li; Stephanie Schulz; Alessandro Bombonati; Juan P Palazzo; Terry Hyslop; Yihuan Xu; Amy A Baran; Linda D Siracusa; Giovanni M Pitari; Scott A Waldman
Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity.
Gastroenterology 2007;133(2):599-607.
2007: Cinzia Sevignani; George A Calin; Stephanie C Nnadi; Masayoshi Shimizu; Ramana V Davuluri; Terry Hyslop; Peter Demant; Carlo M Croce; Linda D Siracusa
MicroRNA genes are frequently located near mouse cancer susceptibility loci.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(19):8017-22.
2007: Amy A Baran; Karen A Silverman; Joseph Zeskand; Revati Koratkar; Ashley Palmer; Kristen McCullen; Walter Curran; Tina Bocker Edmonston; Linda D Siracusa; Arthur M Buchberg
The modifier of Min 2 (Mom2) locus: embryonic lethality of a mutation in the Atp5a1 gene suggests a novel mechanism of polyp suppression.
Genome research 2007;17(5):566-76.
2007: Kelly A McCorkell; Rita Mancini; Z Siprashvili; B L Barnoski; Dimitrios Iliopoulos; Linda D Siracusa; nicola zanesi; Carlo M Croce; Louise Y Y Fong; Teresa Druck; Kay Huebner
Influence of a nonfragile FHIT transgene on murine tumor susceptibility.
Cytogenetic and genome research 2007;118(2-4):196-203.
2006: Cinzia Sevignani; George A Calin; Linda D Siracusa; Carlo M Croce
Mammalian microRNAs: a small world for fine-tuning gene expression.
Mammalian genome : official journal of the International Mammalian Genome Society 2006;17(3):189-202.
2005: Bruce J Herron; Rebecca A Liddell; April Parker; Sarah Grant; Jennifer Kinne; Jill K Fisher; Linda D Siracusa
A mutation in stratifin is responsible for the repeated epilation (Er) phenotype in mice.
Nature genetics 2005;37(11):1210-2.
2005: Marina Markova; Revati Koratkar; Karen A Silverman; Vincent E Sollars; Melina MacPhee-Pellini; Rhonda Walters; Juan P Palazzo; Arthur M Buchberg; Linda D Siracusa; Steven A Farber
Diversity in secreted PLA2-IIA activity among inbred mouse strains that are resistant or susceptible to Apc Min/+ tumorigenesis.
Oncogene 2005;24(42):6450-8.
2004: Marina S Markova; Joseph Zeskand; Benjamin McEntee; Jay Rothstein; Sergio A Jimenez; Linda D Siracusa
A role for the androgen receptor in collagen content of the skin.
The Journal of investigative dermatology 2004;123(6):1052-6.
2004: Revati Koratkar; Karen A Silverman; Ed Pequignot; Walter W Hauck; Arthur M Buchberg; Linda D Siracusa
Analysis of reciprocal congenic lines reveals the C3H/HeJ genome to be highly resistant to ApcMin intestinal tumorigenesis.
Genomics 2004;84(5):844-52.
2004: Kelly B Cha; I Jill Karolyi; A Hunt; A M Wenglikowski; John Wilkinson; David F Dolan; Gary A Dootz; A A Finnegan; Audrey F Seasholtz; Kurt D Hankenson; Linda D Siracusa; Sally A Camper
Skeletal dysplasia and male infertility locus on mouse chromosome 9.
Genomics 2004;83(6):951-60.
2003: Giancarlo Ghiselli; Nefeteria Coffee; Christine E Munnery; Revati Koratkar; Linda D Siracusa
The cohesin SMC3 is a target the for beta-catenin/TCF4 transactivation pathway.
The Journal of biological chemistry 2003;278(22):20259-67.
2003: Karen A Silverman; Revati Koratkar; Linda D Siracusa; Arthur M Buchberg
Exclusion of Madh2, Madh4, and Madh7 as candidates for the modifier of Min 2 (Mom2) locus.
Mammalian genome : official journal of the International Mammalian Genome Society 2003;14(2):119-29.
2002: Revati Koratkar; Ed Pequignot; Walter W Hauck; Linda D Siracusa
The CAST/Ei strain confers significant protection against Apc(Min) intestinal polyps, independent of the resistant modifier of Min 1 (Mom1) locus.
Cancer research 2002;62(19):5413-7.
2002: Karen A Silverman; Revati Koratkar; Linda D Siracusa; Arthur M Buchberg
Identification of the modifier of Min 2 (Mom2) locus, a new mutation that influences Apc-induced intestinal neoplasia.
Genome research 2002;12(1):88-97.
2001: L Dahéron; Thorsten Zenz; Linda D Siracusa; C Brenner; Bruno Calabretta
Molecular cloning of Ian4: a BCR/ABL-induced gene that encodes an outer membrane mitochondrial protein with GTP-binding activity.
Nucleic acids research 2001;29(6):1308-16.
2000: Louise Y Y Fong; Vincenzo Fidanza; nicola zanesi; L F Lock; Linda D Siracusa; Rita Mancini; Z Siprashvili; Michelle Ottey; S Eric Martin; Teresa Druck; Peter McCue; Carlo M Croce; Kay Huebner
Muir-Torre-like syndrome in Fhit-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4742-7.
2000: Luigi Bagella; Peter Stiegler; Antonio De Luca; Linda D Siracusa; Antonio Giordano
Genomic organization, promoter analysis, and chromosomal mapping of the mouse gene encoding Cdk9.
Journal of cellular biochemistry 2000;78(1):170-8.
1999: J Larkin; Marcy Clayton; B Sun; C E Perchonock; J L Morgan; Linda D Siracusa; F H Michaels; Mark A Feitelson
Hepatitis B virus transgenic mouse model of chronic liver disease.
Nature medicine 1999;5(8):907-12.
1999: Giancarlo Ghiselli; Linda D Siracusa; Renato V Iozzo
Complete cDNA cloning, genomic organization, chromosomal assignment, functional characterization of the promoter, and expression of the murine Bamacan gene.
The Journal of biological chemistry 1999;274(24):17384-93.
1999: MJ Fernandes; A A Finnegan; Linda D Siracusa; C Brenner; N N Iscove; Bruno Calabretta
Characterization of a novel receptor that maps near the natural killer gene complex: demonstration of carbohydrate binding and expression in hematopoietic cells.
Cancer research 1999;59(11):2709-17.
1999: Keith G Danielson; Linda D Siracusa; P J Donovan; Renato V Iozzo
Decorin, epiphycan, and lumican genes are closely linked on murine Chromosome 10 and are deleted in lethal steel mutants.
Mammalian genome : official journal of the International Mammalian Genome Society 1999;10(2):201-3.
1998: Linda D Siracusa; Rodney McGrath; J K Fisher; Sergio A Jimenez
The mouse tight skin (Tsk) phenotype is not dependent on the presence of mature T and B lymphocytes.
Mammalian genome : official journal of the International Mammalian Genome Society 1998;9(11):907-9.
1998: yuri pekarsky; Teresa Druck; M G Cotticelli; M Ohta; J Shou; Jeannine M Mendrola; JC Montgomery; Arthur M Buchberg; Linda D Siracusa; Giacomo Manenti; L Y Fong; Tommaso A Dragani; Carlo M Croce; Kay Huebner
The murine Fhit locus: isolation, characterization, and expression in normal and tumor cells.
Cancer research 1998;58(15):3401-8.
1998: Cay M Kielty; M Raghunath; Linda D Siracusa; Michael J Sherratt; R Peters; C Adrian Shuttleworth; S A Jimenez
The Tight skin mouse: demonstration of mutant fibrillin-1 production and assembly into abnormal microfibrils.
The Journal of cell biology 1998;140(5):1159-66.
1998: Jo Peters; Linda D Siracusa; D Pomp; Aamir Zuberi; D Church; Revati Koratkar; C M Abbott
Encyclopedia of the mouse genome VII. Mouse chromosome 2.
Mammalian genome : official journal of the International Mammalian Genome Society 1998;8 Spec No():S27-49.
1997: Linda D Siracusa; C M Abbott; J L Morgan; Aamir Zuberi; D Pomp; Jo Peters
Mouse chromosome 2.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;7 Spec No():S28-44.
1996: Paul J Christner; Linda D Siracusa; D F Hawkins; R McGrath; J K Betz; S T Ball; Sergio A Jimenez; J Peters
A high-resolution linkage map of the tight skin 2 (Tsk2) locus: a mouse model for scleroderma (SSc) and other cutaneous fibrotic diseases.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(8):610-2.
1996: Linda D Siracusa; R McGrath; Q Ma; John Moskow; J Manne; Paul J Christner; Arthur M Buchberg; Sergio A Jimenez
A tandem duplication within the fibrillin 1 gene is associated with the mouse tight skin mutation.
Genome research 1996;6(4):300-13.
1996: P Huber; J Dalmon; J Engiles; F Breviario; S Gory; Linda D Siracusa; Arthur M Buchberg; E Dejana
Genomic structure and chromosomal mapping of the mouse VE-cadherin gene (Cdh5).
Genomics 1996;32(1):21-8.
1996: A C Argeson; K K Nelson; Linda D Siracusa
Molecular basis of the pleiotropic phenotype of mice carrying the hypervariable yellow (Ahvy) mutation at the agouti locus.
Genetics 1996;142(2):557-67.
1996: G Warren; M Gordon; Linda D Siracusa; Arthur M Buchberg; Trevor Williams
Physical and genetic localization of the gene encoding the AP-2 transcription factor to mouse chromosome 13.
Genomics 1996;31(2):234-7.
1996: Linda D Siracusa; J L Morgan; J K Fisher; C M Abbott; Jo Peters
Encyclopedia of the mouse genome V. Mouse chromosome 2.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;6 Spec No():S51-63.
1995: Paul J Christner; J Peters; D Hawkins; Linda D Siracusa; Sergio A Jiménez
The tight skin 2 mouse. An animal model of scleroderma displaying cutaneous fibrosis and mononuclear cell infiltration.
Arthritis and rheumatism 1995;38(12):1791-8.
1995: Christian Praml; Larissa Savelyeva; D Le Paslier; Linda D Siracusa; Arthur M Buchberg; Manfred Schwab; LC Amler
Human homologue of a candidate for the Mom1 locus, the secretory type II phospholipase A2 (PLA2S-II), maps to 1p35-36.1/D1S199.
Cancer research 1995;55(23):5504-6.
1995: M F Naso; J L Morgan; Arthur M Buchberg; Linda D Siracusa; Renato V Iozzo
Expression pattern and mapping of the murine versican gene (Cspg2) to chromosome 13.
Genomics 1995;29(1):297-300.
1995: M MacPhee; K P Chepenik; R A Liddell; K K Nelson; Linda D Siracusa; Arthur M Buchberg
The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia.
Cell 1995;81(6):957-66.
1995: S Haas; A Steplewski; Linda D Siracusa; Shohreh Amini; Kamel Khalili
Identification of a sequence-specific single-stranded DNA binding protein that suppresses transcription of the mouse myelin basic protein gene.
The Journal of biological chemistry 1995;270(21):12503-10.
1995: J Manne; A C Argeson; Linda D Siracusa
Mechanisms for the pleiotropic effects of the agouti gene.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):4721-4.
1995: C M Hustad; W L Perry; Linda D Siracusa; C Rasberry; L Cobb; B M Cattanach; R Kovatch; Neal G Copeland; Nancy A Jenkins
Molecular genetic characterization of six recessive viable alleles of the mouse agouti locus.
Genetics 1995;140(1):255-65.
1995: Linda D Siracusa; L L Washburn; D A Swing; A C Argeson; N A Jenkins; N G Copeland
Hypervariable yellow (Ahvy), a new murine agouti mutation: Ahvy displays the largest variation in coat color phenotypes of all known agouti alleles.
The Journal of heredity 1995;86(2):121-8.
1995: A C Argeson; Teresa Druck; Maria L Veronese; J L Knopf; Arthur M Buchberg; Kay Huebner; Linda D Siracusa
Phospholipase C gamma-2 (Plcg2) and phospholipase C gamma-1 (Plcg1) map to distinct regions in the human and mouse genomes.
Genomics 1995;25(1):29-35.
1995: William J Pavan; R A Liddell; A Wright; G Thibaudeau; P G Matteson; Kirk M McHugh; Linda D Siracusa
A high-resolution linkage map of the lethal spotting locus: a mouse model for Hirschsprung disease.
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(1):1-7.
1994: Linda D Siracusa
The agouti gene: turned on to yellow.
Trends in genetics : TIG 1994;10(12):423-8.
1994: T Scholzen; M Solursh; S Suzuki; R Reiter; J L Morgan; Arthur M Buchberg; Linda D Siracusa; Renato V Iozzo
The murine decorin. Complete cDNA cloning, genomic organization, chromosomal assignment, and expression during organogenesis and tissue differentiation.
The Journal of biological chemistry 1994;269(45):28270-81.
1994: C Goldstein; P Liaw; Sergio A Jimenez; Arthur M Buchberg; Linda D Siracusa
Of mice and Marfan: genetic linkage analyses of the fibrillin genes, Fbn1 and Fbn2, in the mouse genome.
Mammalian genome : official journal of the International Mammalian Genome Society 1994;5(11):696-700.
1994: Linda D Siracusa; C M Abbott
Mouse chromosome 2.
Mammalian genome : official journal of the International Mammalian Genome Society 1994;5 Spec No():S22-39.
1993: Linda D Siracusa; Paul J Christner; R McGrath; S D Mowers; K K Nelson; Sergio A Jimenez
The tight skin (Tsk) mutation in the mouse, a model for human fibrotic diseases, is tightly linked to the beta 2-microglobulin (B2m) gene on chromosome 2.
Genomics 1993;17(3):748-51.
1993: Q Ma; Hansjuerg Alder; K K Nelson; D Chatterjee; Yansong Gu; Tatsuya Nakamura; Eli Canaani; Carlo M Croce; Linda D Siracusa; Arthur M Buchberg
Analysis of the murine All-1 gene reveals conserved domains with human ALL-1 and identifies a motif shared with DNA methyltransferases.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(13):6350-4.
1993: K K Wary; Z Lou; Arthur M Buchberg; Linda D Siracusa; Teresa Druck; S LaForgia; Kay Huebner
A homozygous deletion within the carbonic anhydrase-like domain of the Ptprg gene in murine L-cells.
Cancer research 1993;53(7):1498-502.
1993: J C Marini; K K Nelson; J Battey; Linda D Siracusa
The pituitary hormones arginine vasopressin-neurophysin II and oxytocin-neurophysin I show close linkage with interleukin-1 on mouse chromosome 2.
Genomics 1993;15(1):200-2.
1993: Linda D Siracusa; C M Abbott
Encyclopedia of the mouse genome III. October 1993. Mouse chromosome 2.
Mammalian genome : official journal of the International Mammalian Genome Society 1993;4 Spec No():S31-46.
1992: Linda D Siracusa; C M Abbott
Mouse chromosome 2.
Mammalian genome : official journal of the International Mammalian Genome Society 1992;3 Spec No():S20-43.
1992: K K Nelson; J L Knopf; Linda D Siracusa
Localization of phospholipase C-gamma 1 to mouse chromosome 2.
Mammalian genome : official journal of the International Mammalian Genome Society 1992;3(10):597-600.
1991: Linda D Siracusa
Genomic organization and molecular genetics of the agouti locus in the mouse.
Annals of the New York Academy of Sciences 1991;642():419-30.
1991: Linda D Siracusa; W G Alvord; W A Bickmore; Nancy A Jenkins; Neal G Copeland
Interspecific backcross mice show sex-specific differences in allelic inheritance.
Genetics 1991;128(4):813-21.
1991: Linda D Siracusa; M H Rosner; maria alessandra vigano; DJ Gilbert; Louis M Staudt; Neal G Copeland; Nancy A Jenkins
Chromosomal location of the octamer transcription factors, Otf-1, Otf-2, and Otf-3, defines multiple Otf-3-related sequences dispersed in the mouse genome.
Genomics 1991;10(2):313-26.
1991: Linda D Siracusa; C M Abbott
Mouse chromosome 2.
Mammalian genome : official journal of the International Mammalian Genome Society 1991;1 Spec No():S18-41.
1990: Monica J Justice; Linda D Siracusa; D J Gilbert; N Heisterkamp; J Groffen; K Chada; C M Silan; Neal G Copeland; Nancy A Jenkins
A genetic linkage map of mouse chromosome 10: localization of eighteen molecular markers using a single interspecific backcross.
Genetics 1990;125(4):855-66.
1990: Linda D Siracusa; C M Silan; Monica J Justice; J A Mercer; A R Bauskin; Yinon Ben-Neriah; D Duboule; N D Hastie; Neal G Copeland; Nancy A Jenkins
A molecular genetic linkage map of mouse chromosome 2.
Genomics 1990;6(3):491-504.
1989: Linda D Siracusa; Arthur M Buchberg; Neal G Copeland; Nancy A Jenkins
Recombinant inbred strain and interspecific backcross analysis of molecular markers flanking the murine agouti coat color locus.
Genetics 1989;122(3):669-79.
1987: Linda D Siracusa; L B Russell; E M Eicher; D J Corrow; Neal G Copeland; Nancy A Jenkins
Genetic organization of the agouti region of the mouse.
Genetics 1987;117(1):93-100.
1987: Linda D Siracusa; L B Russell; Nancy A Jenkins; Neal G Copeland
Allelic variation within the Emv-15 locus defines genomic sequences closely linked to the agouti locus on mouse chromosome 2.
Genetics 1987;117(1):85-92.