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Reuben Siraganian

Research Profile

Chemicals & Drugs

Anatomy

Living Beings

Rats
Mouse

Phenomena

Phosphorylation

Physiology

Disorders

Acute Basophilic Leukemia

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Jun-Ichi Kashiwakura; masutaka furue; Kenji Kabashima; Yuko Kawakami; Yoshimichi Okayama; Chisei Ra; Shinji Shimada; Reuben P Siraganian; Toshiaki Kawakami
Most Highly Cytokinergic IgEs Have Polyreactivity to Autoantigens.
Emilia Alina Barbu; Elsa H Berenstein; Jacqueline R Groves; Lauren M Parks; Juan Zhang; Reuben P Siraganian
The transcription factor Zeb2 regulates signaling in mast cells.
Rodrigo Orlandini de Castro; Jacqueline R Groves; Emilia Alina Barbu; Juan Zhang; Reuben P Siraganian
Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation.

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2012: Jun-Ichi Kashiwakura; masutaka furue; Kenji Kabashima; Yuko Kawakami; Yoshimichi Okayama; Chisei Ra; Shinji Shimada; Reuben P Siraganian; Toshiaki Kawakami
Most Highly Cytokinergic IgEs Have Polyreactivity to Autoantigens.
Allergy, asthma & immunology research 2012;4(6):332-40.
2012: Emilia Alina Barbu; Elsa H Berenstein; Jacqueline R Groves; Lauren M Parks; Juan Zhang; Reuben P Siraganian
The transcription factor Zeb2 regulates signaling in mast cells.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(12):6278-86.
2012: Rodrigo Orlandini de Castro; Jacqueline R Groves; Emilia Alina Barbu; Juan Zhang; Reuben P Siraganian
Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation.
The Journal of biological chemistry 2012;287(11):8194-204.
2010: Reuben P Siraganian; Rodrigo O de Castro; Emilia A Barbu; Juan Zhang
Mast cell signaling: the role of protein tyrosine kinase Syk, its activation and screening methods for new pathway participants.
FEBS letters 2010;584(24):4933-40.
2010: Rodrigo O de Castro; Juan Zhang; Maria C Jamur; Constance Oliver; Reuben P Siraganian
Tyrosines in the carboxyl terminus regulate Syk kinase activity and function.
The Journal of biological chemistry 2010;285(34):26674-84.
2010: Juan Zhang; Mary Mendoza; Michel F Guiraldelli; Emilia Alina Barbu; Reuben P Siraganian
Small interfering RNA screen for phosphatases involved in IgE-mediated mast cell degranulation.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(12):7178-85.
2010: Emilia Alina Barbu; Juan Zhang; Reuben P Siraganian
The limited contribution of Fyn and Gab2 to the high affinity IgE receptor signaling in mast cells.
The Journal of biological chemistry 2010;285(21):15761-8.
2009: Ana Cristina G Grodzki; Kyungduk D Moon; Elsa H Berenstein; Reuben P Siraganian
FcepsilonRI-induced activation by low antigen concentrations results in nuclear signals in the absence of degranulation.
Molecular immunology 2009;46(13):2539-47.
2008: Laura M Sly; Janet Kalesnikoff; Vivian Lam; Dana Wong; Christine Song; Stephanie Omeis; Karen Chan; Corinna W K Lee; Reuben P Siraganian; Juan Rivera; Gerald Krystal
IgE-induced mast cell survival requires the prolonged generation of reactive oxygen species.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(6):3850-60.
2008: Michel F Guiraldelli; Elsa Berenstein; Ana Cristina G Grodzki; Reuben P Siraganian; Maria Célia Jamur; Constance Oliver
The low affinity IgG receptor Fc gamma RIIB contributes to the binding of the mast cell specific antibody, mAb BGD6.
Molecular immunology 2008;45(8):2411-8.
2007: Juan Zhang; Katsuhiro Suzuki; Tomohiro Hitomi; Reuben P Siraganian
TOM1L1 is a Lyn substrate involved in FcepsilonRI signaling in mast cells.
The Journal of biological chemistry 2007;282(52):37669-77.
2007: Surajit Ganguly; Cristina Grodzki; David Sugden; Morten Møller; Sandra Odom; Pascaline Gaildrat; Igal Gery; Reuben P Siraganian; Juan Rivera; David Klein
Neural adrenergic/cyclic AMP regulation of the immunoglobulin E receptor alpha-subunit expression in the mammalian pinealocyte: a neuroendocrine/immune response link?
The Journal of biological chemistry 2007;282(45):32758-64.
2007: Constance Oliver; Akira Fujimura; Adriana Maria Mariano Silveira E Souza; Rodrigo Orlandini de Castro; Reuben P Siraganian; Maria Célia Jamur
Mast cell-specific gangliosides and FcepsilonRI follow the same endocytic pathway from lipid rafts in RBL-2H3 cells.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2007;55(4):315-25.
2007: Haifeng Song; Juan Zhang; Y Jeffrey Chiang; Reuben P Siraganian; Richard J Hodes
Redundancy in B cell developmental pathways: c-Cbl inactivation rescues early B cell development through a B cell linker protein-independent pathway.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(2):926-35.
2006: Alessandra Mazzoni; Reuben P Siraganian; Cynthia A Leifer; David M Segal
Dendritic cell modulation by mast cells controls the Th1/Th2 balance in responding T cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(6):3577-81.
2006: Enrique Zudaire; Alfredo Martínez; Mercedes Garayoa; Rubén Pío; Gurmeet Kaur; Michael R Woolhiser; Dean D Metcalfe; William A Hook; Reuben P Siraganian; Theresa A Guise; John M Chirgwin; Frank Cuttitta
Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis.
The American journal of pathology 2006;168(1):280-91.
2005: Maria Célia Jamur; Ana Cristina G Grodzki; Elsa Berenstein; Majed M Hamawy; Reuben P Siraganian; Constance Oliver
Identification and characterization of undifferentiated mast cells in mouse bone marrow.
Blood 2005;105(11):4282-9.
2004: Tomohiro Hitomi; Juan Zhang; Liliana M Nicoletti; Ana Cristina G Grodzki; Maria Célia Jamur; Constance Oliver; Reuben P Siraganian
Phospholipase D1 regulates high-affinity IgE receptor-induced mast cell degranulation.
Blood 2004;104(13):4122-8.
2004: Juan Zhang; Y Jeffrey Chiang; Richard J Hodes; Reuben P Siraganian
Inactivation of c-Cbl or Cbl-b differentially affects signaling from the high affinity IgE receptor.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(3):1811-8.
2004: Katsue Suzuki-Inoue; Jonathan Wilde; Robert K Andrews; Jocelyn M Auger; Reuben P Siraganian; Fujio Sekiya; Sue Goo Rhee; Steve P Watson
Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites.
The Biochemical journal 2004;378(Pt 3):1023-9.
2003: Daniel Vial; Constance Oliver; Maria Célia Jamur; Maria Verônica Dávila Pastor; Edvaldo da Silva Trindade; Elsa Berenstein; Juan Zhang; Reuben P Siraganian
Alterations in granule matrix and cell surface of focal adhesion kinase-deficient mast cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(11):6178-86.
2003: Reuben P Siraganian
Mast cell signal transduction from the high-affinity IgE receptor.
Current opinion in immunology 2003;15(6):639-46.
2002: Juan Zhang; Elsa Berenstein; Reuben P Siraganian
Phosphorylation of Tyr342 in the linker region of Syk is critical for Fc epsilon RI signaling in mast cells.
Molecular and cellular biology 2002;22(23):8144-54.
2002: Reuben P Siraganian; Juan Zhang; Katsuhiro Suzuki; Kiyonao Sada
Protein tyrosine kinase Syk in mast cell signaling.
Molecular immunology 2002;38(16-18):1229-33.
2002: Zhi-Hui Xie; Indu S Ambudkar; Reuben P Siraganian
The adapter molecule Gab2 regulates Fc epsilon RI-mediated signal transduction in mast cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4682-91.
2001: Kiyonao Sada; Juan Zhang; Reuben P Siraganian
SH2 domain-mediated targeting, but not localization, of Syk in the plasma membrane is critical for FcepsilonRI signaling.
Blood 2001;97(5):1352-9.
2001: Maria Célia Jamur; Ana Cristina G Grodzki; Andréa N Moreno; L de F de Mello ; M V Pastor; Elsa Berenstein; Reuben P Siraganian; Constance Oliver
Identification and isolation of rat bone marrow-derived mast cells using the mast cell-specific monoclonal antibody AA4.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(2):219-28.
2000: Juan Zhang; Melvin Billingsley; RL Kincaid; Reuben P Siraganian
Phosphorylation of Syk activation loop tyrosines is essential for Syk function. An in vivo study using a specific anti-Syk activation loop phosphotyrosine antibody.
The Journal of biological chemistry 2000;275(45):35442-7.
2000: D Vial; H Okazaki; Reuben P Siraganian
The NH2-terminal region of focal adhesion kinase reconstitutes high affinity IgE receptor-induced secretion in mast cells.
The Journal of biological chemistry 2000;275(36):28269-75.
2000: Z H Xie; Juan Zhang; Reuben P Siraganian
Positive regulation of c-Jun N-terminal kinase and TNF-alpha production but not histamine release by SHP-1 in RBL-2H3 mast cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1521-8.
2000: Kiyonao Sada; Juan Zhang; Reuben P Siraganian
Point mutation of a tyrosine in the linker region of Syk results in a gain of function.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(1):338-44.
1999: Juan Zhang; Reuben P Siraganian
CD45 is essential for Fc epsilon RI signaling by ZAP70, but not Syk, in Syk-negative mast cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(5):2508-16.
1998: Juan Zhang; T Kimura; Reuben P Siraganian
Mutations in the activation loop tyrosines of protein tyrosine kinase Syk abrogate intracellular signaling but not kinase activity.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(8):4366-74.
1997: H Okazaki; Juan Zhang; Majed M Hamawy; Reuben P Siraganian
Activation of protein-tyrosine kinase Pyk2 is downstream of Syk in FcepsilonRI signaling.
The Journal of biological chemistry 1997;272(51):32443-7.
1997: K Sagawa; T Kimura; M Swieter; Reuben P Siraganian
The protein-tyrosine phosphatase SHP-2 associates with tyrosine-phosphorylated adhesion molecule PECAM-1 (CD31).
The Journal of biological chemistry 1997;272(49):31086-91.
1997: Maria Célia Jamur; Ana Cristina G Grodzki; Andréa N Moreno; William D Swaim; Reuben P Siraganian; Constance Oliver
Immunomagnetic isolation of rat bone marrow-derived and peritoneal mast cells.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1997;45(12):1715-22.
1997: Majed M Hamawy; M Swieter; S E Mergenhagen; Reuben P Siraganian
Reconstitution of high affinity IgE receptor-mediated secretion by transfecting protein tyrosine kinase pp125FAK.
The Journal of biological chemistry 1997;272(48):30498-503.
1997: T Kimura; Juan Zhang; K Sagawa; K Sakaguchi; Ettore Appella; Reuben P Siraganian
Syk-independent tyrosine phosphorylation and association of the protein tyrosine phosphatases SHP-1 and SHP-2 with the high affinity IgE receptor.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(9):4426-34.
1997: Majed M Hamawy; C Fischler; Juan Zhang; Reuben P Siraganian
Fc epsilon RI aggregation induces tyrosine phosphorylation of a novel 72 kDa protein downstream of Syk.
Biochemical and biophysical research communications 1997;239(3):670-5.
1997: T Kimura; H Sakamoto; Ettore Appella; Reuben P Siraganian
The negative signaling molecule SH2 domain-containing inositol-polyphosphate 5-phosphatase (SHIP) binds to the tyrosine-phosphorylated beta subunit of the high affinity IgE receptor.
The Journal of biological chemistry 1997;272(21):13991-6.
1997: K Sagawa; William D Swaim; Juan Zhang; Edward Joseph Unsworth; Reuben P Siraganian
Aggregation of the high affinity IgE receptor results in the tyrosine phosphorylation of the surface adhesion protein PECAM-1 (CD31).
The Journal of biological chemistry 1997;272(20):13412-8.
1997: Cloris Ditzel Faraco; I Vugman; Reuben P Siraganian; Maria Célia Jamur; Constance Oliver
Immunocytochemical identification of immature rat peritoneal mast cells using a monoclonal antibody specific for rat mast cells.
Acta histochemica 1997;99(1):23-7.
1997: Majed M Hamawy; Reuben P Siraganian
Large scale isolation of intact rat basophilic leukemia (RBL-2H3) cells.
Journal of immunological methods 1997;201(1):11-4.
1997: V Stephan; Annette Seibt; D Dukanovic; M Skasa; William D Swaim; Elsa Berenstein; Reuben P Siraganian; Volker Wahn
Anti-ganglioside monoclonal antibody AA4 selectively inhibits IgE-induced signal transduction pathways in rat basophilic leukemia cells.
Molecular immunology 1997;34(3):227-35.
1996: T Kimura; H Kihara; S Bhattacharyya; H Sakamoto; Ettore Appella; Reuben P Siraganian
Downstream signaling molecules bind to different phosphorylated immunoreceptor tyrosine-based activation motif (ITAM) peptides of the high affinity IgE receptor.
The Journal of biological chemistry 1996;271(44):27962-8.
1996: Juan Zhang; E H Berenstein; R L Evans; Reuben P Siraganian
Transfection of Syk protein tyrosine kinase reconstitutes high affinity IgE receptor-mediated degranulation in a Syk-negative variant of rat basophilic leukemia RBL-2H3 cells.
The Journal of experimental medicine 1996;184(1):71-9.
1996: T Kimura; H Sakamoto; Ettore Appella; Reuben P Siraganian
Conformational changes induced in the protein tyrosine kinase p72syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides.
Molecular and cellular biology 1996;16(4):1471-8.
1995: M Swieter; E H Berenstein; Reuben P Siraganian
Protein tyrosine phosphatase activity associates with the high affinity IgE receptor and dephosphorylates the receptor subunits, but not Lyn or Syk.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(11):5330-6.
1995: M Swieter; E H Berenstein; William D Swaim; Reuben P Siraganian
Aggregation of IgE receptors in rat basophilic leukemia 2H3 cells induces tyrosine phosphorylation of the cytosolic protein-tyrosine phosphatase HePTP.
The Journal of biological chemistry 1995;270(37):21902-6.
1995: Majed M Hamawy; S E Mergenhagen; Reuben P Siraganian
Protein tyrosine phosphorylation as a mechanism of signalling in mast cells and basophils.
Cellular signalling 1995;7(6):535-44.
1995: Majed M Hamawy; K Minoguchi; William D Swaim; S E Mergenhagen; Reuben P Siraganian
A 77-kDa protein associates with pp125FAK in mast cells and becomes tyrosine-phosphorylated by high affinity IgE receptor aggregation.
The Journal of biological chemistry 1995;270(20):12305-9.
1995: Maria Célia Jamur; C D Faraco; L O Lunardi; Reuben P Siraganian; Constance Oliver
Microwave fixation improves antigenicity of glutaraldehyde-sensitive antigens while preserving ultrastructural detail.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1995;43(3):307-11.
1994: Majed M Hamawy; William D Swaim; K Minoguchi; A W de Feijter; S E Mergenhagen; Reuben P Siraganian
The aggregation of the high affinity IgE receptor induces tyrosine phosphorylation of paxillin, a focal adhesion protein.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(10):4655-62.
1994: M Benhamou; E H Berenstein; M H Jouvin; Reuben P Siraganian
The receptor with high affinity for IgE on rat mast cells is a functional receptor for rat IgG2a.
Molecular immunology 1994;31(14):1089-97.
1994: H Kihara; Reuben P Siraganian
Src homology 2 domains of Syk and Lyn bind to tyrosine-phosphorylated subunits of the high affinity IgE receptor.
The Journal of biological chemistry 1994;269(35):22427-32.
1994: William D Swaim; K Minoguchi; C Oliver; Majed M Hamawy; H Kihara; V Stephan; E H Berenstein; Reuben P Siraganian
The anti-ganglioside monoclonal antibody AA4 induces protein tyrosine phosphorylations, but not degranulation, in rat basophilic leukemia cells.
The Journal of biological chemistry 1994;269(30):19466-73.
1994: K Minoguchi; M Benhamou; William D Swaim; Y Kawakami; T Kawakami; Reuben P Siraganian
Activation of protein tyrosine kinase p72syk by Fc epsilon RI aggregation in rat basophilic leukemia cells. p72syk is a minor component but the major protein tyrosine kinase of pp72.
The Journal of biological chemistry 1994;269(24):16902-8.
1994: K Minoguchi; H Kihara; H Nishikata; Majed M Hamawy; Reuben P Siraganian
Src family tyrosine kinase Lyn binds several proteins including paxillin in rat basophilic leukemia cells.
Molecular immunology 1994;31(7):519-29.
1994: K Minoguchi; William D Swaim; E H Berenstein; Reuben P Siraganian
Src family tyrosine kinase p53/56lyn, a serine kinase and Fc epsilon RI associate with alpha-galactosyl derivatives of ganglioside GD1b in rat basophilic leukemia RBL-2H3 cells.
The Journal of biological chemistry 1994;269(7):5249-54.
1994: Majed M Hamawy; S E Mergenhagen; Reuben P Siraganian
Adhesion molecules as regulators of mast-cell and basophil function.
Immunology today 1994;15(2):62-6.
1993: M Benhamou; Nicholas J P Ryba; H Kihara; H Nishikata; Reuben P Siraganian
Protein-tyrosine kinase p72syk in high affinity IgE receptor signaling. Identification as a component of pp72 and association with the receptor gamma chain after receptor aggregation.
The Journal of biological chemistry 1993;268(31):23318-24.
1993: M Swieter; Majed M Hamawy; Reuben P Siraganian; S E Mergenhagen
Mast cells and their microenvironment: the influence of fibronectin and fibroblasts on the functional repertoire of rat basophilic leukemia cells.
Journal of periodontology 1993;64(5 Suppl):492-6.
1993: Majed M Hamawy; S E Mergenhagen; Reuben P Siraganian
Tyrosine phosphorylation of pp125FAK by the aggregation of high affinity immunoglobulin E receptors requires cell adherence.
The Journal of biological chemistry 1993;268(10):6851-4.
1993: Majed M Hamawy; S E Mergenhagen; Reuben P Siraganian
Cell adherence to fibronectin and the aggregation of the high affinity immunoglobulin E receptor synergistically regulate tyrosine phosphorylation of 105-115-kDa proteins.
The Journal of biological chemistry 1993;268(7):5227-33.
1993: M Swieter; R J Midura; H Nishikata; C Oliver; E H Berenstein; S E Mergenhagen; Vincent C Hascall; Reuben P Siraganian
Mouse 3T3 fibroblasts induce rat basophilic leukemia (RBL-2H3) cells to acquire responsiveness to compound 48/80.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(2):617-24.
1992: H Nishikata; C Oliver; S E Mergenhagen; Reuben P Siraganian
The rat mast cell antigen AD1 (homologue to human CD63 or melanoma antigen ME491) is expressed in other cells in culture.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(3):862-70.
1992: Majed M Hamawy; C Oliver; S E Mergenhagen; Reuben P Siraganian
Adherence of rat basophilic leukemia (RBL-2H3) cells to fibronectin-coated surfaces enhances secretion.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(2):615-21.
1992: M Benhamou; Reuben P Siraganian
Protein-tyrosine phosphorylation: an essential component of Fc epsilon RI signaling.
Immunology today 1992;13(6):195-7.
1992: M Benhamou; V Stephan; K C Robbins; Reuben P Siraganian
High-affinity IgE receptor-mediated stimulation of rat basophilic leukemia (RBL-2H3) cells induces early and late protein-tyrosine phosphorylations.
The Journal of biological chemistry 1992;267(11):7310-4.
1992: V Stephan; M Benhamou; J Silvio Gutkind; K C Robbins; Reuben P Siraganian
Fc epsilon RI-induced protein tyrosine phosphorylation of pp72 in rat basophilic leukemia cells (RBL-2H3). Evidence for a novel signal transduction pathway unrelated to G protein activation and phosphatidylinositol hydrolysis.
The Journal of biological chemistry 1992;267(8):5434-41.
1992: C Oliver; N Sahara; S Kitani; A R Robbins; L M Mertz; Reuben P Siraganian
Binding of monoclonal antibody AA4 to gangliosides on rat basophilic leukemia cells produces changes similar to those seen with Fc epsilon receptor activation.
The Journal of cell biology 1992;116(3):635-46.
1992: Majed M Hamawy; C Oliver; Reuben P Siraganian
Inhibition of IgE binding to RBL-2H3 cells by a monoclonal antibody (BD6) to a surface protein other than the high affinity IgE receptor.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(2):524-31.
1992: M Swieter; S E Mergenhagen; Reuben P Siraganian
Microenvironmental factors that influence mast cell phenotype and function.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1992;199(1):22-33.
1991: W A Hook; E H Berenstein; F U Zinsser; C Fischler; Reuben P Siraganian
Monoclonal antibodies to the leukocyte common antigen (CD45) inhibit IgE-mediated histamine release from human basophils.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(8):2670-6.
1991: John O Cisar; E L Barsumian; Reuben P Siraganian; W B Clark; MK Yeung; S D Hsu; S H Curl; A E Vatter; Ann L Sandberg
Immunochemical and functional studies of Actinomyces viscosus T14V type 1 fimbriae with monoclonal and polyclonal antibodies directed against the fimbrial subunit.
Journal of general microbiology 1991;137(8):1971-9.
1991: V Stephan; N Guo; V Ginsburg; Reuben P Siraganian
Immunoprecipitation of membrane proteins from rat basophilic leukemia cells by the antiganglioside monoclonal antibody AA4.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(12):4271-7.
1991: W A Hook; F U Zinsser; E H Berenstein; Reuben P Siraganian
Monoclonal antibodies defining epitopes on human IgE.
Molecular immunology 1991;28(6):631-9.
1991: S Kitani; E Berenstein; S Mergenhagen; Paul Tempst; Reuben P Siraganian
A cell surface glycoprotein of rat basophilic leukemia cells close to the high affinity IgE receptor (Fc epsilon RI). Similarity to human melanoma differentiation antigen ME491.
The Journal of biological chemistry 1991;266(3):1903-9.
1990: Ann L Sandberg; John O Cisar; Reuben P Siraganian; L L Mudrick; M W Armstrong
Complement activation by individual and combinations of monoclonal antibodies to Actinomyces viscosus T14V fimbriae: a probe for epitope distribution on these polymeric proteins.
Molecular immunology 1990;27(8):787-94.
1990: M Benhamou; J Silvio Gutkind; K C Robbins; Reuben P Siraganian
Tyrosine phosphorylation coupled to IgE receptor-mediated signal transduction and histamine release.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(14):5327-30.
1990: N Sahara; Reuben P Siraganian; C Oliver
Morphological changes induced by the calcium ionophore A23187 in rat basophilic leukemia (2H3) cells.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1990;38(7):975-83.
1989: P Tempro; Frederick J Cassels; Reuben P Siraganian; A R Hand; J London
Use of adhesin-specific monoclonal antibodies to identify and localize an adhesin on the surface of Capnocytophaga gingivalis DR2001.
Infection and immunity 1989;57(11):3418-24.
1988: S Kitani; D Kraft; C Fischler; S E Mergenhagen; Reuben P Siraganian
Inhibition of allergic reactions with monoclonal antibody to the high affinity IgE receptor.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(8):2585-8.
1988: Ervin I Weiss; J London; Paul E Kolenbrander; A R Hand; Reuben P Siraganian
Localization and enumeration of fimbria-associated adhesins of Bacteroides loescheii.
Journal of bacteriology 1988;170(3):1123-8.
1988: Ervin I Weiss; J London; Paul E Kolenbrander; Roxanna N Andersen; C Fischler; Reuben P Siraganian
Characterization of monoclonal antibodies to fimbria-associated adhesins of Bacteroides loescheii PK1295.
Infection and immunity 1988;56(1):219-24.
1987: M L Stracke; L K Basciano; C Fischler; E H Berenstein; Reuben P Siraganian
Characterization of monoclonal antibodies produced by immunization with partially purified IgE receptor complexes.
Molecular immunology 1987;24(4):347-56.
1987: M L Stracke; L K Basciano; Reuben P Siraganian
Binding properties and histamine release in variants of rat basophilic leukemia cells with changes in the IgE receptor.
Immunology letters 1987;14(4):287-92.
1986: L K Basciano; E H Berenstein; L Kmak; Reuben P Siraganian
Monoclonal antibodies that inhibit IgE binding.
The Journal of biological chemistry 1986;261(25):11823-31.
1985: E L Barsumian; A McGivney; L K Basciano; Reuben P Siraganian
Establishment of four mouse mastocytoma cell lines.
Cellular immunology 1985;90(1):131-41.
1983: Reuben P Siraganian; C Urata; A McGivney
Arachidonic acid release during IgE- and Ca2+ -ionophore activation of rat basophilic leukemia cells.
Monographs in allergy 1983;18():120-3.
1982: P C Fox; L K Basciano; Reuben P Siraganian
Mouse mast cell activation and desensitization for immune aggregate-induced histamine release.
Journal of immunology (Baltimore, Md. : 1950) 1982;129(1):314-9.
1982: Reuben P Siraganian; A McGivney; E L Barsumian; Fulton T Crews; Fusao Hirata; Julius Axelrod
Variants of the rat basophilic leukemia cell line for the study of histamine release.
Federation proceedings 1982;41(1):30-4.
1981: A McGivney; Y Morita; Fulton T Crews; Fusao Hirata; Julius Axelrod; Reuben P Siraganian
Phospholipase activation in the IgE-mediated and Ca2+ ionophore A23187-induced release of histamine from rat basophilic leukemia cells.
Archives of biochemistry and biophysics 1981;212(2):572-80.
1981: Fulton T Crews; Y Morita; A McGivney; Fusao Hirata; Reuben P Siraganian; Julius Axelrod
IgE-mediated histamine release in rat basophilic leukemia cells: receptor activation, phospholipid methylation, Ca2+ flux, and release of arachidonic acid.
Archives of biochemistry and biophysics 1981;212(2):561-71.
1981: A McGivney; Fulton T Crews; Fusao Hirata; Julius Axelrod; Reuben P Siraganian
Rat basophilic leukemia cell lines defective in phospholipid methyltransferase enzymes, Ca2+ influx, and histamine release: reconstitution by hybridization.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(10):6176-80.
1981: John O Cisar; E L Barsumian; S H Curl; A E Vatter; Ann L Sandberg; Reuben P Siraganian
Detection and localization of a lectin on Actinomyces viscosus T14V by monoclonal antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1981;127(4):1318-22.
1981: E L Barsumian; C Isersky; M G Petrino; Reuben P Siraganian
IgE-induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones.
European journal of immunology 1981;11(4):317-23.
1980: John O Cisar; E L Barsumian; S H Curl; A E Vatter; Ann L Sandberg; Reuben P Siraganian
The use of monoclonal antibodies in the study of lactose-sensitive adherence of Actinomyces viscosus T14V.
Journal of the Reticuloendothelial Society 1980;28(Suppl):73s-79s.