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Cherilyn Sirois

Research Profile

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Publications

TOP 3
Kamalpreet Nagpal; Theo S Plantinga; Cherilyn M Sirois; Brian G Monks; Eicke Latz; Mihai G Netea; Douglas T Golenbock
Natural loss-of-function mutation of myeloid differentiation protein 88 disrupts its ability to form Myddosomes.
Leonie Unterholzner; Sinead E Keating; Marcin Baran; Kristy A Horan; Søren B Jensen; Shruti Sharma; Cherilyn M Sirois; Tengchuan Jin; Eicke Latz; T Sam Xiao; Katherine A Fitzgerald; Søren R Paludan; Andrew G Bowie
IFI16 is an innate immune sensor for intracellular DNA.
Pearl Gray; Kathrin S Michelsen; Cherilyn M Sirois; Emily Lowe; Kenichi Shimada; Timothy R Crother; Shuang Chen; Constantinos Brikos; Yonca Bulut; Eicke Latz; David Underhill; Moshe Arditi
Identification of a novel human MD-2 splice variant that negatively regulates Lipopolysaccharide-induced TLR4 signaling.

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All Publications

2011: Kamalpreet Nagpal; Theo S Plantinga; Cherilyn M Sirois; Brian G Monks; Eicke Latz; Mihai G Netea; Douglas T Golenbock
Natural loss-of-function mutation of myeloid differentiation protein 88 disrupts its ability to form Myddosomes.
The Journal of biological chemistry 2011;286(13):11875-82.
2010: Leonie Unterholzner; Sinead E Keating; Marcin Baran; Kristy A Horan; Søren B Jensen; Shruti Sharma; Cherilyn M Sirois; Tengchuan Jin; Eicke Latz; T Sam Xiao; Katherine A Fitzgerald; Søren R Paludan; Andrew G Bowie
IFI16 is an innate immune sensor for intracellular DNA.
Nature immunology 2010;11(11):997-1004.
2010: Pearl Gray; Kathrin S Michelsen; Cherilyn M Sirois; Emily Lowe; Kenichi Shimada; Timothy R Crother; Shuang Chen; Constantinos Brikos; Yonca Bulut; Eicke Latz; David Underhill; Moshe Arditi
Identification of a novel human MD-2 splice variant that negatively regulates Lipopolysaccharide-induced TLR4 signaling.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(11):6359-66.
2010: Peter Duewell; Hajime Kono; Katey J Rayner; Cherilyn M Sirois; Gregory Vladimer; Franz G Bauernfeind; George S Abela; luigi franchi; Gabriel Nuñez; Max Schnurr; Terje Espevik; Egil Lien; Katherine A Fitzgerald; Kenneth L Rock; Kathryn J Moore; Samuel D Wright; Veit Hornung; Eicke Latz
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Nature 2010;464(7293):1357-61.
2007: Eicke Latz; Anjali Verma; Alberto Visintin; Mei Gong; Cherilyn M Sirois; David C Klein; Brian G Monks; C James McKnight; Marc S Lamphier; W Paul Duprex; Terje Espevik; Douglas T Golenbock
Ligand-induced conformational changes allosterically activate Toll-like receptor 9.
Nature immunology 2007;8(7):772-9.
2007: Jane Tian; Ana Maria Avalos; Su-Yau Mao; Bo Chen; Kannaki Senthil; Herren Wu; Peggy Parroche; Stacey V Drabic; Douglas T Golenbock; Cherilyn M Sirois; Jing Hua; Ling Ling An; Laurent P Audoly; Greg La Rosa; Angelika Bierhaus; Peter Naworth; Ann Marshak-Rothstein; Mary Crow; Katherine A Fitzgerald; Eicke Latz; Peter Kiener; Anthony J Coyle
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.
Nature immunology 2007;8(5):487-96.
2006: Marc S Lamphier; Cherilyn M Sirois; Anjali Verma; Douglas T Golenbock; Eicke Latz
TLR9 and the recognition of self and non-self nucleic acids.
Annals of the New York Academy of Sciences 2006;1082():31-43.