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Pierre Sirois

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Luciana M C Vasquez-Pinto; François Nantel; Pierre Sirois; Sonia Jancar
Bradykinin B(1) receptor antagonist R954 inhibits eosinophil activation/proliferation/migration and increases TGF-beta and VEGF in a murine model of asthma.
Quan Yang; Bruno Battistini; Stephane Pelletier; Pierre Sirois
Inhibition of basal and stimulated release of endothelin-1 from guinea pig tracheal epithelial cells in culture by beta 2-adrenoceptor agonists and cyclic AMP enhancers.
Martin Richter; Solange Cloutier; Pierre Sirois
Endothelin, PAF and thromboxane A2 in allergic pulmonary hyperreactivity in mice.

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2010: Luciana M C Vasquez-Pinto; François Nantel; Pierre Sirois; Sonia Jancar
Bradykinin B(1) receptor antagonist R954 inhibits eosinophil activation/proliferation/migration and increases TGF-beta and VEGF in a murine model of asthma.
Neuropeptides 2010;44(2):107-13.
2007: Quan Yang; Bruno Battistini; Stephane Pelletier; Pierre Sirois
Inhibition of basal and stimulated release of endothelin-1 from guinea pig tracheal epithelial cells in culture by beta 2-adrenoceptor agonists and cyclic AMP enhancers.
Inflammation 2007;30(5):136-47.
2007: Martin Richter; Solange Cloutier; Pierre Sirois
Endothelin, PAF and thromboxane A2 in allergic pulmonary hyperreactivity in mice.
Prostaglandins, leukotrienes, and essential fatty acids 2007;76(5):299-308.
2007: Monica C Toffoli; Bichoy H Gabra; Catarina F P Teixeira; Pierre Sirois; Sonia Jancar
Endothelins mediate neutrophil activation, ProMMP-9 release and endothelial cell detachment.
Inflammation 2007;30(1-2):28-37.
2006: Philippe Daull; André Blouin; Karine Belleville; Myriam Beaudoin; D Arsenault; H Leonard; Pierre Sirois; François Nantel; Arco Y Jeng; Bruno Battistini
Triple VPI CGS 35601 reduces high blood pressure in low-renin, high-salt Dahl salt-sensitive rats.
Experimental biology and medicine (Maywood, N.J.) 2006;231(6):830-3.
2006: Philippe Daull; André Blouin; Myriam Beaudoin; S Gadbois; Karine Belleville; Julie Cayer; Nathalie Berthiaume; Pierre Sirois; François Nantel; Arco Y Jeng; Bruno Battistini
The hemodynamic and metabolic profiles of Zucker diabetic fatty rats treated with a single molecule triple vasopeptidase inhibitor, CGS 35601.
Experimental biology and medicine (Maywood, N.J.) 2006;231(6):824-9.
2006: François Nantel; Philippe Daull; Nathalie Berthiaume; Dana-Nicoleta Duta; André Blouin; Julie Cayer; Myriam Beaudoin; Karine Belleville; Ouhida Benrezzak; Pierre Sirois; Bruno Battistini
Integrated in vivo pharmacology using an instrumented, unrestrained and conscious rat platform: application to rat models of diabetes.
Journal of pharmacological and toxicological methods 2006;53(3):248-55.
2006: Bichoy H Gabra; Nathalie Berthiaume; Pierre Sirois; François Nantel; Bruno Battistini
The kinin system mediates hyperalgesia through the inducible bradykinin B1 receptor subtype: evidence in various experimental animal models of type 1 and type 2 diabetic neuropathy.
Biological chemistry 2006;387(2):127-43.
2006: Philippe Daull; R Lepage; Ouhida Benrezzak; Julie Cayer; Myriam Beaudoin; Karine Belleville; André Blouin; Pierre Sirois; François Nantel; Arco Y Jeng; Bruno Battistini
The first preclinical pharmacotoxicological safety assessment of CGS 35601, a triple vasopeptidase inhibitor, in chronically instrumented, conscious, and unrestrained spontaneously hypertensive rats.
Drug and chemical toxicology 2006;29(2):183-202.
2005: Philippe Daull; Ouhida Benrezzak; Dominique Arsenault; Leng Hong Pheng; André Blouin; Julie Cayer; Myriam Beaudoin; Karine Belleville; Pierre Sirois; François Nantel; Arco Y Jeng; Bruno Battistini
Triple vasopeptidase inhibition normalizes blood pressure in conscious, unrestrained, and spontaneously hypertensive rats.
American journal of hypertension 2005;18(12 Pt 1):1606-13.
2005: Philippe Daull; André Blouin; Julie Cayer; Myriam Beaudoin; Karine Belleville; Pierre Sirois; François Nantel; T M S Chang; Bruno Battistini
Profiling biochemical and hemodynamic markers using chronically instrumented, conscious and unrestrained rats undergoing severe, acute controlled hemorrhagic hypovolemic shock as an integrated in-vivo model system to assess new blood substitutes.
Vascular pharmacology 2005;43(4):289-301.
2005: Bichoy H Gabra; Ouhida Benrezzak; Leng Hong Pheng; Dana Duta; Philippe Daull; Pierre Sirois; François Nantel; Bruno Battistini
Inhibition of type 1 diabetic hyperalgesia in streptozotocin-induced Wistar versus spontaneous gene-prone BB/Worchester rats: efficacy of a selective bradykinin B1 receptor antagonist.
Journal of neuropathology and experimental neurology 2005;64(9):782-9.
2005: Sibi R Lawson; Bichoy H Gabra; François Nantel; Bruno Battistini; Pierre Sirois
Effects of a selective bradykinin B1 receptor antagonist on increased plasma extravasation in streptozotocin-induced diabetic rats: distinct vasculopathic profile of major key organs.
European journal of pharmacology 2005;514(1):69-78.
2005: Bichoy H Gabra; Pierre Sirois
Hyperalgesia in non-obese diabetic (NOD) mice: a role for the inducible bradykinin B1 receptor.
European journal of pharmacology 2005;514(1):61-7.
2005: Bichoy H Gabra; Vanessa F Merino; Michael Bader; João B Pesquero; Pierre Sirois
Absence of diabetic hyperalgesia in bradykinin B1 receptor-knockout mice.
Regulatory peptides 2005;127(1-3):245-8.
2005: Sibi R Lawson; Bichoy H Gabra; Brigitte Guérin; Witold Neugebauer; François Nantel; Bruno Battistini; Pierre Sirois
Enhanced dermal and retinal vascular permeability in streptozotocin-induced type 1 diabetes in Wistar rats: blockade with a selective bradykinin B1 receptor antagonist.
Regulatory peptides 2005;124(1-3):221-4.
2004: Bichoy H Gabra; Pierre Sirois
Pathways for the bradykinin B1 receptor-mediated diabetic hyperalgesia in mice.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2004;53(12):653-7.
2004: Philippe Daull; André Blouin; Pierre Sirois; François Nantel; Arco Y Jeng; Bruno Battistini
Triple vasopeptidase inhibition of angiotensin-converting enzyme/neutral endopeptidase/endothelin-converting enzyme activities on the hemodynamic profile of chronically instrumented unrestrained conscious spontaneously hypertensive rats.
Journal of cardiovascular pharmacology 2004;44 Suppl 1():S398-401.
2004: Ouhida Benrezzak; Hélène Marois; Philippe Daull; André Blouin; Raymond Lepage; Pierre Sirois; François Nantel; Bruno Battistini
Profile of endothelin isopeptides and markers of oxidative stress alongside the onset of streptozotocin-type I diabetes in rats.
Journal of cardiovascular pharmacology 2004;44 Suppl 1():S168-72.
2004: Catarina F P Teixeira; Sonia Jancar; W T Lima; P D'Orléans-Juste; Pierre Sirois
Association of endothelin with lung hemorrhage induced by immune complexes in rats.
Inflammation 2004;28(5):253-61.
2004: Karim Maghni; François Nantel; Chantal Lanoue; Solange Cloutier; Jean-Paul Cristol; Alain Cadieux; Pierre Sirois
Role of airway eosinophilia and eosinophil activation in Sephadex-induced inflammation.
Inflammation 2004;28(4):195-206.
2004: Richardt Gama Landgraf; Sonia Jancar; Ana Angélica Steil; Pierre Sirois
Modulation of allergic and immune complex-induced lung inflammation by bradykinin receptor antagonists.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2004;53(2):78-83.
2004: Gabrielle Gendron; Bryan Simard; Fernand Gobeil; Pierre Sirois; Pedro D'Orléans-Juste; Domenico Regoli
Human urotensin-II enhances plasma extravasation in specific vascular districts in Wistar rats.
Canadian journal of physiology and pharmacology 2004;82(1):16-21.
2003: Bichoy H Gabra; Réjean Couture; Pierre Sirois
[Functional duality of kinin receptors in pathophysiology].
Médecine sciences : M/S 2003;19(11):1101-10.
2003: Ewa Zaczynska; Bichoy H Gabra; Pierre Sirois
Bradykinin stimulates MMP-2 production in guinea pig tracheal smooth muscle cells.
Inflammation 2003;27(5):307-15.
2003: Jadranka Eric; Ghassan Bkaily; Ghassan B Bkaily; Leonid Volkov; Bichoy H Gabra; Pierre Sirois
Des-Arg9-bradykinin increases intracellular Ca2+ in bronchoalveolar eosinophils from ovalbumin-sensitized and -challenged mice.
European journal of pharmacology 2003;475(1-3):129-37.
2003: Bichoy H Gabra; Pierre Sirois
Beneficial effect of chronic treatment with the selective bradykinin B1 receptor antagonists, R-715 and R-954, in attenuating streptozotocin-diabetic thermal hyperalgesia in mice.
Peptides 2003;24(8):1131-9.
2003: Jadranka Eric; Bichoy H Gabra; Pierre Sirois
Implication of the bradykinin receptors in antigen-induced pulmonary inflammation in mice.
British journal of pharmacology 2003;138(8):1589-97.
2003: Bichoy H Gabra; Pierre Sirois
Kinin B1 receptor antagonists inhibit diabetes-induced hyperalgesia in mice.
Neuropeptides 2003;37(1):36-44.
2003: Richardt Gama Landgraf; Pierre Sirois; Sonia Jancar
Differential modulation of murine lung inflammation by bradykinin B1 and B2 selective receptor antagonists.
European journal of pharmacology 2003;460(1):75-83.
2002: Bichoy H Gabra; Pierre Sirois
Role of bradykinin B(1) receptors in diabetes-induced hyperalgesia in streptozotocin-treated mice.
European journal of pharmacology 2002;457(2-3):115-24.
2002: Bryan Simard; Bichoy H Gabra; Pierre Sirois
Inhibitory effect of a novel bradykinin B1 receptor antagonist, R-954, on enhanced vascular permeability in type 1 diabetic mice.
Canadian journal of physiology and pharmacology 2002;80(12):1203-7.
2002: Pierre J Farmer; Daphné Girardot; Andrée Lepage; Domenico Regoli; Pierre Sirois
Inhibition of prostaglandin G/H synthase unveils a potent effect of platelet activating factor on the permeability of bovine aortic endothelial cells to albumin.
Inflammation 2002;26(6):253-8.
2002: Richard Béliveau; Denis Gingras; Erwin A Kruger; Sylvie Lamy; Pierre Sirois; Bryan Simard; Martin G Sirois; Leone Tranqui; Fabienne Baffert; Edith Beaulieu; Violetta Dimitriadou; Marie-Claude Pépin; Frank Courjal; Isabelle Ricard; Patrick Poyet; Pierre Falardeau; William D Figg; Eric Dupont
The antiangiogenic agent neovastat (AE-941) inhibits vascular endothelial growth factor-mediated biological effects.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(4):1242-50.
2001: Pierre J Farmer; SG Bernier; Andrée Lepage; Gaétan Guillemette; Domenico Regoli; Pierre Sirois
Permeability of endothelial monolayers to albumin is increased by bradykinin and inhibited by prostaglandins.
American journal of physiology. Lung cellular and molecular physiology 2001;280(4):L732-8.
2001: Celso Carv alho; Sonia Jancar; D Conroy; Pierre Sirois
Antigen-induced bronchial hyperreactivity and bronchopulmonary inflammation in rats: effect of TNF receptor binding protein.
Experimental lung research 2001;27(2):107-19.
2001: Stephane Pelletier; J Dubé; A Villeneuve; Fernand Gobeil; Q Yang; Bruno Battistini; Gaétan Guillemette; Pierre Sirois
Prostaglandin E(2) increases cyclic AMP and inhibits endothelin-1 production/secretion by guinea-pig tracheal epithelial cells through EP(4) receptors.
British journal of pharmacology 2001;132(5):999-1008.
2000: Dung Pham; AY Jeng; Emanuel Escher; Pierre Sirois; Bruno Battistini
Effects of a selective neutral endopeptidase and a nonselective neutral endopeptidase/endothelin-converting enzyme inhibitor on lipopolysaccharide-induced endotoxaemia in anaesthetized Sprague-Dawley rats.
Journal of cardiovascular pharmacology 2000;36(5 Suppl 1):S362-6.
2000: JG O'Brien; Bruno Battistini; F Zaharia; Gérard E Plante; Pierre Sirois
Effects of tranexamic acid and aprotinin, two antifibrinolytic drugs, on PAF-induced plasma extravasation in unanesthetized rats.
Inflammation 2000;24(5):411-29.
2000: J F Blain; Pierre Sirois
Involvement of LTD(4)in allergic pulmonary inflammation in mice: modulation by cysLT(1)antagonist MK-571.
Prostaglandins, leukotrienes, and essential fatty acids 2000;62(6):361-8.
2000: Rana Samadfam; C Teixeira; Ghassan Bkaily; Pierre Sirois; Artur J de Brum-Fernandes; Pedro D'Orleans-Juste
Contribution of B(2) receptors for bradykinin in arthus reaction-induced plasma extravasation in wild-type or B(2) transgenic knockout mice.
British journal of pharmacology 2000;129(8):1732-8.
2000: Martin Richter; Pierre Sirois
Effects of eicosanoids, neuromediators and bioactive peptides on murine airways.
European journal of pharmacology 2000;389(2-3):225-34.
2000: Stephane Pelletier; J Dubé; A Villeneuve; Fernand Gobeil; SG Bernier; Bruno Battistini; Gaétan Guillemette; Pierre Sirois
Adenosine induces cyclic-AMP formation and inhibits endothelin-1 production/secretion in guinea-pig tracheal epithelial cells through A(2B) adenosine receptors.
British journal of pharmacology 2000;129(2):243-50.
1999: D M Conroy; Pierre Sirois
Early bronchial hyperresponsiveness following injection of sephadex beads in the guinea pig: involvement of platelet activating factor and thromboxane A2.
Inflammation 1999;23(5):437-48.
1999: M S Perron; Fernand Gobeil; Stephane Pelletier; Domenico Regoli; Pierre Sirois
Involvement of bradykinin B1 and B2 receptors in pulmonary leukocyte accumulation induced by Sephadex beads in guinea pigs.
European journal of pharmacology 1999;376(1-2):83-9.
1999: J F Blain; Karim Maghni; Stephane Pelletier; Pierre Sirois
Evidence for the activation of blood complement in Sephadex beads-induced lung inflammation in guinea pigs.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48(7):386-92.
1999: D Arseneault; Karim Maghni; Pierre Sirois
Selective inflammatory response induced by intratracheal and intravenous administration of poly-L-arginine in guinea pig lungs.
Inflammation 1999;23(3):287-304.
1999: C Carvalho; Sonia Jancar; M Mariano; Pierre Sirois
A rat model presenting eosinophilia in the airways, lung eosinophil activation, and pulmonary hyperreactivity.
Experimental lung research 1999;25(4):303-16.
1998: C Carvalho; Sonia Jancar; Pierre Sirois
Inhibition of airway hyperreactivity, edema, and lung cell infiltration by compound U-83836E in sensitized guinea pigs.
Canadian journal of physiology and pharmacology 1998;76(7-8):715-20.
1998: Stephane Pelletier; Bruno Battistini; Pierre Sirois
Adenosine-induced inhibition of basal endothelin-1 production from guinea-pig tracheal epithelial cells: a mechanism involving the release of cAMP.
Pulmonary pharmacology & therapeutics 1998;11(2-3):237-42.
1998: Bruno Battistini; Ana Angélica Steil; Sonia Jancar; Pierre Sirois
Roles of endothelins and their receptors in immune complex-induced/polymorphonuclear-mediated lung injury (reversed passive arthus reaction) in CD-1 mice.
Pulmonary pharmacology & therapeutics 1998;11(2-3):165-72.
1998: Pierre Borgeat; Serge Picard; B Battistini; Pierre Sirois
Measurements of arachidonic acid metabolites derived from the lipoxygenase pathways by high-pressure liquid chromatography.
Methods in molecular biology (Clifton, N.J.) 1998;105():209-16.
1998: B Battistini; Serge Picard; Pierre Borgeat; Pierre Sirois
Measurements of prostanoids, leukotrienes, and isoprostanes by enzyme immunoassays.
Methods in molecular biology (Clifton, N.J.) 1998;105():201-7.
1998: B Battistini; Serge Picard; Pierre Borgeat; Pierre Sirois
Extraction and measurements of prostanoids and leukotrienes by radioimmunoassays.
Methods in molecular biology (Clifton, N.J.) 1998;105():187-99.
1998: Stephane Pelletier; Bruno Battistini; AY Jeng; Pierre Sirois
Effects of dual endothelin-converting enzyme/neutral endopeptidase inhibitors, CGS 26303 and CGS 26393, on lipopolysaccharide or interleukin-1 beta-stimulated release of endothelin from guinea pig tracheal epithelial cells.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S10-2.
1997: Jean-Philippe Gratton; G Cournoyer; B M Löffler; Pierre Sirois; Pedro D'Orléans-Juste
ET(B) receptor and nitric oxide synthase blockade induce BQ-123-sensitive pressor effects in the rabbit.
Hypertension 1997;30(5):1204-9.
1997: Q Yang; T Kawaguchi; Bruno Battistini; Pierre Sirois
Neutral endopeptidase degrades endothelins in guinea pig tracheal epithelial cells.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1997;46 Suppl 2():S171-2.
1997: Pierre J Farmer; Andrée Lepage; JG O'Brien; C F Bélanger; Bruno Battistini; Gérard E Plante; Domenico Regoli; Pierre Sirois
DesArg9BK increases the permeability of bovine aortic endothelial monolayer to iodinated albumin.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1997;46 Suppl 2():S149-50.
1997: JG O'Brien; P Farmer; Bruno Battistini; R J Johnson; F Zaharia; Pierre Sirois
Effects of tranexamic acid and aprotinin on PAF-induced vascular permeability in normal, thrombocytopenic or neutropenic rats.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1997;46 Suppl 2():S145-6.
1997: JG O'Brien; Bruno Battistini; P Farmer; R J Johnson; F Zaharia; Gérard E Plante; Pierre Sirois
Aprotinin, an antifibrinolytic drug, attenuates bradykinin-induced permeability in conscious rats via platelets and neutrophils.
Canadian journal of physiology and pharmacology 1997;75(6):741-9.
1997: Q Yang; J Laporte; Bruno Battistini; Pierre Sirois
Effects of dexamethasone on the basal and cytokine-stimulated release of endothelin-1 from guinea-pig cultured tracheal epithelial cells.
Canadian journal of physiology and pharmacology 1997;75(6):576-81.
1997: Q Yang; Bruno Battistini; Pedro D'Orléans-Juste; AY Jeng; Pierre Sirois
Modulation of endothelin production and metabolism in guinea-pig tracheal epithelial cells by peptidase inhibitors.
American journal of respiratory and critical care medicine 1997;155(6):1884-9.
1997: D Dumitriu; S Prié; SG Bernier; Gaétan Guillemette; Pierre Sirois
Mechanism of action of leukotriene D4 on guinea pig tracheal smooth muscle cells: roles of Ca++ influx and intracellular Ca++ release.
The Journal of pharmacology and experimental therapeutics 1997;280(3):1357-65.
1997: J Laporte; Pierre Sirois
Phosphoramidon and thiorphan suppress the generation of endothelin (ET) from exogenous big-endothelin by guinea pig Clara cells.
Regulatory peptides 1997;68(2):105-9.
1996: S Prié; D M Conroy; G J Gleich; Pierre Sirois
Eosinophils and neutrophils modify arachidonic acid-induced relaxation of guinea-pig trachea.
European journal of pharmacology 1996;317(2-3):343-51.
1996: N Pouliot; Karim Maghni; F Blanchette; L Cironi; Pierre Sirois; Jana Stankova; Marek Rola-Pleszczynski
Natural killer and lectin-dependent cytotoxic activities of Kurloff cells: target cell selectivity, conjugate formation, and Ca++ dependency.
Inflammation 1996;20(6):647-71.
1996: Karim Maghni; M J Simard; D Arseneault; Pierre Sirois
Kinetics of eosinophilia and eosinophil activation in the development of non-allergic bronchial hyperresponsiveness in guinea pigs injected with Sephadex beads.
Inflammation 1996;20(5):523-35.
1996: A Ponton; Jean-Paul Thirion; Pierre Sirois
Changes in chromatin conformation regulate the 5-lipoxygenase gene expression during differentiation of HL60 cells.
Prostaglandins, leukotrienes, and essential fatty acids 1996;55(3):139-43.
1996: Gérard E Plante; M Chakir; K Ettaouil; S Lehoux; Pierre Sirois
Consequences of alteration in capillary permeability.
Canadian journal of physiology and pharmacology 1996;74(7):824-33.
1996: N Pouliot; Karim Maghni; Pierre Sirois; Marek Rola-Pleszczynski
Guinea pig Kurloff (NK-like) cells mediate TNF-dependent cytotoxic activity: analogy with NC effector cells.
Inflammation 1996;20(3):263-80.
1996: Caroline Patry; E Müller; J Laporte; Marek Rola-Pleszczynski; Pierre Sirois; Artur J de Brum-Fernandes
Leukotriene receptors in HL-60 cells differentiated into eosinophils, monocytes and neutrophils.
Prostaglandins, leukotrienes, and essential fatty acids 1996;54(5):361-70.
1996: J Laporte; Pedro D'Orléans-Juste; Pierre Sirois
Guinea pig Clara cells secrete endothelin 1 through a phosphoramidon-sensitive pathway.
American journal of respiratory cell and molecular biology 1996;14(4):356-62.
1996: Gérard E Plante; S Lehoux; Pierre Sirois
Drug-induced alteration of endothelial permeability in the rat aorta. Potential consequences on the vessel wall.
Advances in experimental medicine and biology 1996;416():249-53.
1996: Pedro D'Orléans-Juste; A Claing; D Regoli; Pierre Sirois; Gérard E Plante
Endothelial and smooth muscle pharmacology of pre- and post-capillary microcirculation: correlation with plasma extravasation.
Prostaglandins, leukotrienes, and essential fatty acids 1996;54(1):31-7.
1996: N Lebel; Pedro D'Orléans-Juste; Alain Fournier; Pierre Sirois
Role of the neutral endopeptidase 24.11 in the conversion of big endothelins in guinea-pig lung parenchyma.
British journal of pharmacology 1996;117(1):184-8.
1995: S Prié; Gaétan Guillemette; Guylain Boulay; Pierre Borgeat; Pierre Sirois
Leukotriene C4 receptors on guinea pig tracheocytes.
The Journal of pharmacology and experimental therapeutics 1995;275(1):312-8.
1995: D M Conroy; S St-Pierre; Pierre Sirois
Relaxant effects of pituitary adenylate cyclase activating polypeptide (PACAP) on epithelium-intact and -denuded guinea-pig trachea: a comparison with vasoactive intestinal peptide (VIP).
Neuropeptides 1995;29(3):121-7.
1995: Karim Maghni; M J Simard; S Cloutier; D Arseneault; Pierre Sirois
Relationship between the development of bronchial hyperresponsiveness and the airway eosinophilia in guinea pigs following injection with Sephadex beads.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1995;44 Suppl 2():S174-6.
1995: S Y Martineau; Karim Maghni; M Chakir; Gérard E Plante; Pierre Sirois
Specific increase of microvascular permeability in lower airways of guinea pigs injected with Sephadex beads.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1995;44 Suppl 2():S168-9.
1995: D Arseneault; Karim Maghni; Pierre Sirois
Granulocyte recruitment in guinea pig lungs following the administration of MBP-like cationic protein.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1995;44 Suppl 2():S166-7.
1995: J F Blain; Karim Maghni; Pierre Sirois
Activation of blood complement in guinea pigs receiving an intravenous injection of Sephadex beads.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1995;44 Suppl 2():S158-9.
1995: W T de Lima; F H Kwasniewski; Pierre Sirois; Sonia Jancar
Studies on the mechanism of PAF-induced vasopermeability in rat lungs.
Prostaglandins, leukotrienes, and essential fatty acids 1995;52(4):245-9.
1995: D M Conroy; J N Francischi; Pierre Sirois
Effect of tumor necrosis factor receptor binding protein on cell infiltration induced by lipopolysaccharide and Sephadex beads in guinea pig lung.
Inflammation 1995;19(2):233-43.
1995: N Lebel; Pedro D'Orléans-Juste; Alain Fournier; Pierre Sirois
Characterization of the endothelin-converting enzyme in guinea pig upper bronchus.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S81-3.
1995: J Laporte; Pedro D'Orléans-Juste; G Singh; Pierre Sirois
Dexamethasone and phosphoramidon inhibit endothelin release by cultured nonciliated bronchiolar epithelial (Clara) cells.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S53-5.
1994: E Földes-Filep; Pierre Sirois; János G Filep
Pulmonary surfactant lipids inhibit prostanoid production of guinea pig alveolar macrophages.
Journal of leukocyte biology 1994;56(4):475-80.
1994: C Robidoux; Karim Maghni; J Laporte; A Ponton; A Hallée; Pierre Borgeat; Pierre Sirois
Highly purified guinea pig type II pneumocytes have the leukotriene A4 hydrolase but do not express 5-lipoxygenase activity.
Prostaglandins, leukotrienes, and essential fatty acids 1994;51(4):263-70.
1994: A Claing; Ghassan Bkaily; N Berthiaume; Pierre Sirois; Marek Rola-Pleszczynski; Pedro D'Orléans-Juste
Role of R-type calcium channels in the response of the perfused arterial and venous mesenteric vasculature of the rat to platelet-activating factor.
British journal of pharmacology 1994;112(4):1202-8.
1994: S Lehoux; M G Sirois; Pierre Sirois; Gérard E Plante
Acute and chronic diuretic treatment selectively affects vascular permeability in the unanesthetized normal rat.
The Journal of pharmacology and experimental therapeutics 1994;269(3):1094-9.
1994: M G Sirois; W T de Lima; Artur J de Brum-Fernandes; R J Johnson; Gérard E Plante; Pierre Sirois
Effect of PAF on rat lung vascular permeability: role of platelets and polymorphonuclear leucocytes.
British journal of pharmacology 1994;111(4):1111-6.
1994: K Li; Pierre Sirois; J L Rouleau
Role of endothelial cells in cardiovascular function.
Life sciences 1994;54(9):579-92.
1993: J Nogueira de Francischi; D M Conroy; Karim Maghni; Pierre Sirois
Inhibition by rapamycin of leukocyte migration and bronchial hyperreactivity induced by injection of Sephadex beads to guinea-pigs.
British journal of pharmacology 1993;110(4):1381-6.
1993: János G Filep; E Földes-Filep; A Rousseau; Pierre Sirois; Alain Fournier
Vascular responses to endothelin-1 following inhibition of nitric oxide synthesis in the conscious rat.
British journal of pharmacology 1993;110(3):1213-21.
1993: Karim Maghni; F Blanchette; Pierre Sirois
Induction of lung eosinophilia and neutrophilia in guinea pigs following injection of sephadex beads.
Inflammation 1993;17(5):537-50.
1993: J N Francischi; D M Conroy; S Cloutier; Pierre Sirois
Reduction of Sephadex-induced lung inflammation and bronchial hyperreactivity by rapamycin.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1993;26(10):1105-10.
1993: János G Filep; Bruno Battistini; Alain Fournier; Pierre Sirois
Relaxation by dexamethasone of isolated guinea-pig airways precontracted with endothelin-1.
European journal of pharmacology 1993;240(2-3):315-8.
1993: János G Filep; S Télémaque; Bruno Battistini; Pierre Sirois; Pedro D'Orléans-Juste
Increased plasma levels of endothelin during anaphylactic shock in the guinea-pig.
European journal of pharmacology 1993;239(1-3):231-6.
1993: János G Filep; M G Sirois; E Földes-Filep; A Rousseau; Gérard E Plante; Alain Fournier; M Yano; Pierre Sirois
Enhancement by endothelin-1 of microvascular permeability via the activation of ETA receptors.
British journal of pharmacology 1993;109(3):880-6.
1993: János G Filep; Bruno Battistini; Pierre Sirois
Induction by endothelin-1 of epithelium-dependent relaxation of guinea-pig trachea in vitro: role for nitric oxide.
British journal of pharmacology 1993;109(3):637-44.
1993: Bruno Battistini; Pedro D'Orléans-Juste; Pierre Sirois
Endothelins: circulating plasma levels and presence in other biologic fluids.
Laboratory investigation; a journal of technical methods and pathology 1993;68(6):600-28.
1993: Bruno Battistini; Pierre Chailler; Pedro D'Orléans-Juste; N Brière; Pierre Sirois
Growth regulatory properties of endothelins.
Peptides 1993;14(2):385-99.
1993: Karim Maghni; J Carrier; S Cloutier; Pierre Sirois
Cell-cell interactions between platelets, macrophages, eosinophils and natural killer cells in thromboxane A2 biosynthesis.
Journal of lipid mediators 1993;6(1-3):321-32.
1993: M Nicolau; M G Sirois; M Bui; Gérard E Plante; Pierre Sirois; D Regoli
Plasma extravasation induced by neurokinins in conscious rats: receptor characterization with agonists and antagonists.
Canadian journal of physiology and pharmacology 1993;71(3-4):217-21.
1993: János G Filep; E Földes-Filep; Pierre Sirois
Nitric oxide modulates vascular permeability in the rat coronary circulation.
British journal of pharmacology 1993;108(2):323-6.
1993: M G Sirois; Gérard E Plante; P Farmer; Pierre Sirois
Platelet activating factor modulates peptidoleukotriene effects on the permeability of bovine aortic endothelial cell to albumin.
Agents and actions 1993;39 Spec No():C17-20.
1993: Bruno Battistini; M Germain; Alain Fournier; Pierre Sirois
Structure-activity relationships of ET-1 and selected analogues in the isolated guinea pig trachea: evidence for the existence of different ETB receptor subtypes.
Journal of cardiovascular pharmacology 1993;22 Suppl 8():S219-24.
1993: J N Francischi; D Conroy; Karim Maghni; Pierre Sirois
Rapamycin inhibits airway leukocyte infiltration and hyperreactivity in guinea pigs.
Agents and actions 1993;39 Spec No():C139-41.
1992: S Lehoux; Gérard E Plante; M G Sirois; Pierre Sirois; Pedro D'Orléans-Juste
Phosphoramidon blocks big-endothelin-1 but not endothelin-1 enhancement of vascular permeability in the rat.
British journal of pharmacology 1992;107(4):996-1000.
1992: János G Filep; A Rousseau; Alain Fournier; Pierre Sirois
Structure-activity relationship of analogues of endothelin-1: dissociation of hypotensive and pressor actions.
European journal of pharmacology 1992;220(2-3):263-6.
1992: János G Filep; E Földes-Filep; A Rousseau; Alain Fournier; Pierre Sirois; M Yano
Endothelin-1 enhances vascular permeability in the rat heart through the ETA receptor.
European journal of pharmacology 1992;219(2):343-4.
1992: A Chopra; D L Ferreira-Alves; Pierre Sirois; Jean-Paul Thirion
Cloning of the guinea pig 5-lipoxygenase gene and nucleotide sequence of its promoter.
Biochemical and biophysical research communications 1992;185(2):489-95.
1992: Y P Côté; János G Filep; Bruno Battistini; J Gauvreau; Pierre Sirois; Adrien R Beaudoin
Characterization of ATP-diphosphohydrolase activities in the intima and media of the bovine aorta: evidence for a regulatory role in platelet activation in vitro.
Biochimica et biophysica acta 1992;1139(1-2):133-42.
1992: Gérard E Plante; M Bissonnette; M G Sirois; D Regoli; Pierre Sirois
Renal permeability alteration precedes hypertension and involves bradykinin in the spontaneously hypertensive rat.
The Journal of clinical investigation 1992;89(6):2030-2.
1992: M G Sirois; János G Filep; A Rousseau; Alain Fournier; Gérard E Plante; Pierre Sirois
Endothelin-1 enhances vascular permeability in conscious rats: role of thromboxane A2.
European journal of pharmacology 1992;214(2-3):119-25.
1992: W T de Lima; Pierre Sirois; Sonia Jancar
Immune-complex alveolitis in the rat: evidence for platelet activating factor and leukotrienes as mediators of the vascular lesions.
European journal of pharmacology 1992;213(1):63-70.
1992: E Földes-Filep; János G Filep; Pierre Sirois
C-reactive protein inhibits intracellular calcium mobilization and superoxide production by guinea pig alveolar macrophages.
Journal of leukocyte biology 1992;51(1):13-8.
1991: Gérard E Plante; J Dubé; L Bouffard; Pierre Sirois
Sodium-phosphate cotransport and vascular reactivity.
Clinical and investigative medicine. Médecine clinique et experimentale 1991;14(6):545-50.
1991: János G Filep; M G Sirois; A Rousseau; Alain Fournier; Pierre Sirois
Effects of endothelin-1 on vascular permeability in the conscious rat: interactions with platelet-activating factor.
British journal of pharmacology 1991;104(4):797-804.
1991: Artur J de Brum-Fernandes; Gaétan Guillemette; Pierre Borgeat; Pierre Sirois
Specific binding sites for leukotriene B4 in guinea pig brain membranes.
The Journal of pharmacology and experimental therapeutics 1991;259(3):1035-42.
1991: Sonia Jancar; Catarina F P Teixeira; W T de Lima; A Y Fujimura; Pierre Sirois
Inhibitory effect of econazole on the release of thromboxanes.
Agents and actions 1991;34(3-4):387-92.
1991: Sonia Jancar; M G Sirois; J Carrier; P Braquet; Pierre Sirois
PAF induces rat plasma extravasation and releases eicosanoids during anaphylaxis.
Inflammation 1991;15(5):347-54.
1991: Karim Maghni; C Robidoux; J Laporte; A Hallee; Pierre Borgeat; Pierre Sirois
Purification of natural killer-like Kurloff cells and arachidonic acid metabolism.
Prostaglandins 1991;42(3):251-67.
1991: Pierre Sirois; Pierre Borgeat; M Lauzière; L Dubé; P Rubin; J Kesterson
Effect of Zileuton (A-64077) on the 5-lipoxygenase activity of human whole blood ex vivo.
Agents and actions 1991;34(1-2):117-20.
1991: Karim Maghni; Artur J de Brum-Fernandes; E Földes-Filep; M Gaudry; Pierre Borgeat; Pierre Sirois
Leukotriene B4 receptors on guinea pig alveolar eosinophils.
The Journal of pharmacology and experimental therapeutics 1991;258(3):784-9.
1991: János G Filep; Bruno Battistini; Pierre Sirois
Pharmacological modulation of endothelin-induced contraction of guinea-pig isolated airways and thromboxane release.
British journal of pharmacology 1991;103(3):1633-40.
1991: János G Filep; Bruno Battistini; Y P Côté; Adrien R Beaudoin; Pierre Sirois
Endothelin-1 induces prostacyclin release from bovine aortic endothelial cells.
Biochemical and biophysical research communications 1991;177(1):171-6.
1991: S Prié; Karim Maghni; J Laporte; Pierre Borgeat; Pierre Sirois
Synthesis of eicosanoids by isolated guinea pig tracheocytes.
The American journal of physiology 1991;260(4 Pt 1):L349-55.
1991: Bruno Battistini; János G Filep; E J Cragoe; Alain Fournier; Pierre Sirois
A role for Na+/H+ exchange in contraction of guinea pig airways by endothelin-1 in vitro.
Biochemical and biophysical research communications 1991;175(2):583-8.
1991: J Laporte; A Hallee; Karim Maghni; C Robidoux; Pierre Borgeat; Pierre Sirois
Metabolism of arachidonic acid by guinea pig Clara cells.
Prostaglandins 1991;41(3):263-81.
1991: J C Le Guennec; M Lauzière; R Black; Pierre Sirois
Effects of indomethacin on prostaglandin E2 and thromboxane B2 contents of tracheal lavage fluids in premature infants.
Inflammation 1991;15(1):55-9.
1991: Pierre Sirois; Karim Maghni; C Robidoux; A Hallée; J Laporte; S Cloutier; Pierre Borgeat
Metabolism of arachidonic acid by Foà-Kurloff cells from guinea pig lungs and spleen.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21A():437-40.
1991: Karim Maghni; C Robidoux; J Laporte; A Hallée; J Carrier; Pierre Borgeat; Pierre Sirois
Metabolism of arachidonic acid by isolated lung cells and transcellular biosynthesis of thromboxanes.
Advances in experimental medicine and biology 1991;314():289-306.
1991: János G Filep; F Hermán; Bruno Battistini; P E Chabrier; P Braquet; Pierre Sirois
Antiaggregatory and hypotensive effects of endothelin-1 in beagle dogs: role for prostacyclin.
Journal of cardiovascular pharmacology 1991;17 Suppl 7():S216-8.
1990: M G Sirois; Gérard E Plante; P Braquet; Pierre Sirois
Role of eicosanoids in PAF-induced increases of the vascular permeability in rat airways.
British journal of pharmacology 1990;101(4):896-900.
1990: Artur J de Brum-Fernandes; Gaétan Guillemette; Pierre Sirois
Leukotriene B4 binding sites in guinea-pig alveolar macrophages.
Prostaglandins 1990;40(5):515-27.
1990: Bruno Battistini; János G Filep; F Hermán; Pierre Sirois
Endothelin-1 does not affect human platelet aggregation in whole blood and platelet rich plasma.
Thrombosis research 1990;60(1):105-8.
1990: Bruno Battistini; Pierre Sirois; P Braquet; János G Filep
Endothelin-induced constriction of guinea pig airways: role of platelet-activating factor.
European journal of pharmacology 1990;186(2-3):307-10.
1990: Alain Cadieux; C Lanoue; Pierre Sirois; J Barabé
Carbamylcholine- and 5-hydroxytryptamine-induced contraction in rat isolated airways: inhibition by calcitonin gene-related peptide.
British journal of pharmacology 1990;101(1):193-9.
1990: Karim Maghni; C Robidoux; J Laporte; A Hallée; Pierre Sirois
Release of prostaglandins and thromboxanes by guinea pig isolated type II pneumocytes.
Prostaglandins 1990;40(2):217-27.
1990: Bruno Battistini; János G Filep; Pierre Sirois
Potent thromboxane-mediated in vitro bronchoconstrictor effect of endothelin in the guinea-pig.
European journal of pharmacology 1990;178(1):141-2.
1990: K Hirata; Karim Maghni; Pierre Borgeat; Pierre Sirois
Guinea pig alveolar eosinophils and macrophages produce leukotriene B4 but no peptido-leukotriene.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(5):1880-5.
1990: D Fecchio; Pierre Sirois; M Russo; Sonia Jancar
Studies on inflammatory response induced by Ehrlich tumor in mice peritoneal cavity.
Inflammation 1990;14(1):125-32.
1990: D Fecchio; M Russo; Pierre Sirois; P Braquet; Sonia Jancar
Inhibition of Ehrlich ascites tumor in vivo by PAF-antagonists.
International journal of immunopharmacology 1990;12(1):57-65.
1990: S Prié; Alain Cadieux; Pierre Sirois
Removal of guinea pig bronchial and tracheal epithelium potentiates the contractions to leukotrienes and histamine.
Eicosanoids 1990;3(1):29-37.
1990: János G Filep; Bruno Battistini; Pierre Sirois
Endothelin induces thromboxane release and contraction of isolated guinea-pig airways.
Life sciences 1990;47(20):1845-50.
1990: M G Sirois; Gérard E Plante; P Braquet; Pierre Sirois
Tumor necrosis factor primes the effects of platelet-activating factor on rat vascular permeability.
Journal of lipid mediators 1990;2 Suppl():S109-17.
1989: Sonia Jancar; P Braquet; Pierre Sirois
Release of eicosanoids in rat peritoneal cavity stimulated with platelet-activating factor (PAF). Effect of the PAF-antagonist BN-52021.
Prostaglandins, leukotrienes, and essential fatty acids 1989;37(1):23-4.
1989: K Hirata; J P Pelé; C Robidoux; Pierre Sirois
Guinea pig lung eosinophil: purification and prostaglandin production.
Journal of leukocyte biology 1989;45(6):523-8.
1989: R L Hébert; Pierre Sirois; Gérard E Plante
Inhibition of platelet-activating factor induced renal hemodynamic and tubular dysfunctions with L-655,240, a new thromboxane-prostaglandin endoperoxide antagonist.
Canadian journal of physiology and pharmacology 1989;67(4):304-8.
1989: Gérard E Plante; C Prévost; Pierre Sirois; C Rochat; J F Prost
Tertatolol increases glomerular filtration and urinary sodium in anesthetized rats.
The Journal of pharmacology and experimental therapeutics 1989;248(2):741-6.
1989: J P Pelé; C Robidoux; Pierre Sirois
Guinea pig lung cells. Method of isolation and partial purification, identification, ultrastructure, and cell count.
Inflammation 1989;13(1):103-23.
1989: Sonia Jancar; P Thériault; Pierre Sirois
Effect of PAF on selected smooth muscle preparations.
Research communications in chemical pathology and pharmacology 1989;63(1):157-60.
1989: Wothan Tavares de Lima; Catarina F P Teixeira; Pierre Sirois; Sonia Jancar
Involvement of eicosanoids and PAF in immune-complex alveolitis.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1989;22(6):745-8.
1989: J P Cristol; B Provençal; Pierre Sirois
Leukotriene receptors.
Journal of receptor research 1989;9(4-5):341-67.
1989: Sonia Jancar; P Braquet; Pierre Sirois
Release of eicosanoids in rat peritoneal cavity during the Arthus reaction. Effect of the PAF-antagonist BN-52021 and indomethacin.
International journal of immunopharmacology 1989;11(2):129-32.
1989: Sonia Jancar; P Thériault; M Lauzière; P Braquet; Pierre Sirois
Paf-induced release of spasmogens from guinea-pig lungs.
British journal of pharmacology 1989;96(1):153-62.
1989: J P Pelé; C Robidoux; Pierre Sirois
Secretion of thromboxane B2 and prostaglandin E2 by guinea-pig lung cells isolated by centrifugal elutriation and by macrophages obtained by bronchoalveolar lavage.
Pulmonary pharmacology 1989;2(3):137-45.
1988: Gérard E Plante; A Chainey; Pierre Sirois; M Devissaguet
Angiotensin converting enzyme inhibition and autoregulation of glomerular filtration.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1988;6(3):S69-73.
1988: J P Cristol; B Provençal; Pierre Borgeat; Pierre Sirois
Characterization of leukotriene B4 binding sites on guinea pig lung macrophages.
The Journal of pharmacology and experimental therapeutics 1988;247(3):1199-203.
1988: M G Sirois; Sonia Jancar; P Braquet; Gérard E Plante; Pierre Sirois
PAF increases vascular permeability in selected tissues: effect of BN-52021 and L-655,240.
Prostaglandins 1988;36(5):631-44.
1988: Gérard E Plante; Pierre Sirois; P Braquet
Platelet activating factor antagonism with BN52021 protects the kidney against acute ischemic injury.
Prostaglandins, leukotrienes, and essential fatty acids 1988;34(1):53-60.
1988: S Prié; Pierre Sirois
Mechanism of action of leukotrienes on the guinea pig bronchus.
Prostaglandins, leukotrienes, and essential fatty acids 1988;34(1):19-25.
1988: Sonia Jancar; P Thériault; B Provençal; S Cloutier; Pierre Sirois
Mechanism of action of platelet-activating factor on guinea-pig lung parenchyma strips.
Canadian journal of physiology and pharmacology 1988;66(9):1187-91.
1988: C Robidoux; J P Pelé; J Maclouf; P Pradelles; Pierre Sirois
Stimulation of release of prostaglandins and thromboxanes from isolated guinea pig lung cells by bradykinin, f-Met-Leu-Phe, phorbol myristate, ionophore A23187, and leukotrienes.
Inflammation 1988;12(4):285-95.
1988: J P Cristol; B Provençal; Pierre Borgeat; Pierre Sirois
Specific leukotriene D4 receptors on guinea-pig alveolar macrophages.
Prostaglandins 1988;35(5):747-56.
1988: C Robidoux; J Maclouf; P Pradelles; Pierre Sirois
Release of prostaglandin E2 and thromboxane B2 by mixed isolated human lung cells.
Prostaglandins, leukotrienes, and essential fatty acids 1988;32(1):23-8.
1988: J P Cristol; Pierre Sirois
Comparative activity of leukotriene D4, 5,6-dihydroxy-eicosatetraenoic acid and lipoxin A on guinea pig lung parenchyma and ileum smooth muscle.
Research communications in chemical pathology and pharmacology 1988;59(3):423-6.
1988: Pierre Sirois; Jolanta Gutkowska
Atrial natriuretic factor immunoreactivity in human fetal lung tissue and perfusates.
Hypertension 1988;11(2 Pt 2):I62-5.
1988: C Kandaswami; G Morin; Pierre Sirois
Lipid peroxidation in rat alveolar macrophages exposed to chrysotile fibres.
Toxicology in vitro : an international journal published in association with BIBRA 1988;2(2):117-20.
1987: Pierre Sirois; S Prié; P Thériault; G Rouleau; M Lauzière
Guinea pig bronchus as a model for icosanoid studies.
Inflammation 1987;11(4):447-57.
1987: Sonia Jancar; P Thériault; P Braquet; Pierre Sirois
Comparative effects of platelet activating factor, leukotriene D4 and histamine on guinea pig trachea, bronchus and lung parenchyma.
Prostaglandins 1987;33(2):199-208.
1987: Sonia Jancar; P Braquet; Pierre Sirois
Interactions of arachidonic acid metabolites and platelet activating factor and mechanism of action in hypersensitivity reactions.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1987;20(5):487-94.
1987: Pierre Sirois; M Harczy; P Braquet; Pierre Borgeat; J Maclouf; P Pradelles
Inhibition of the release of prostaglandins, thromboxanes, and leukotrienes from anaphylactic lungs by a platelet-activating factor (PAF) antagonist and its stimulation by PAF.
Advances in prostaglandin, thromboxane, and leukotriene research 1987;17B():1033-7.