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Luigi Sironi

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Sara Di Castro; Enrico Duranti; Paolo Gelosa; Simona Marchitti; Luigi Ruco; Stefania Scarpino; Luigi Sironi; Rosita Stanzione; Massimo Volpe; Franca Bianchi; Maria Cotugno; Speranza Rubattu
Differential modulation of uncoupling protein 2 in kidneys of stroke-prone spontaneously hypertensive rats under high-salt/low-potassium diet.
Elisabetta Gianazza; Cristina Sensi; Luigi Sironi; Robin Wait; Ivano Eberini; Ingrid Miller
Proteomics of rat biological fluids--the tenth anniversary update.
Luigi Sironi; Paolo Gelosa
'Les liaisons dangereuses': the inextricable link between blood pressure and kidney. The hypertensive rat strains as a possibility to untangle it.

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All Publications

2013: Sara Di Castro; Enrico Duranti; Paolo Gelosa; Simona Marchitti; Luigi Ruco; Stefania Scarpino; Luigi Sironi; Rosita Stanzione; Massimo Volpe; Franca Bianchi; Maria Cotugno; Speranza Rubattu
Differential modulation of uncoupling protein 2 in kidneys of stroke-prone spontaneously hypertensive rats under high-salt/low-potassium diet.
Hypertension 2013;61(2):534-41.
2012: Elisabetta Gianazza; Cristina Sensi; Luigi Sironi; Robin Wait; Ivano Eberini; Ingrid Miller
Proteomics of rat biological fluids--the tenth anniversary update.
Journal of proteomics 2012;75(11):3113-28.
2012: Luigi Sironi; Paolo Gelosa
'Les liaisons dangereuses': the inextricable link between blood pressure and kidney. The hypertensive rat strains as a possibility to untangle it.
Journal of hypertension 2012;30(6):1101-2.
2012: Silvana Penco; Alice Pignieri; Silvana Pileggi; Mauro Abbate; Paolo Gelosa; Uliano Guerrini; Alessandro Marocchi; Elena Tremoli; Luigi Sironi
Is the SHRSP [corrected] strain a suitable model of spontaneous CADASIL?
Journal of molecular neuroscience : MN 2012;46(2):427-30.
2012: Elena Nobili; M Dolores Salvado; Luigi Sironi; Elena Tremoli; Anders Wetterholm; Laura Castiglioni; Lasse Folkersen; Jesper Z Haeggström; Göran K Hansson; Jens Kastrup; Anders Gabrielsen
Cysteinyl leukotriene signaling aggravates myocardial hypoxia in experimental atherosclerotic heart disease.
PloS one 2012;7(7):e41786.
2011: Matteo Franzosi; Uliano Guerrini; Elena Nobili; Luigi Sironi; Elena Tremoli; Laura Castiglioni; Enrico G Caiani
Feasibility of quantitative analysis of regional left ventricular function in the post-infarct mouse by magnetic resonance imaging with retrospective gating.
Computers in biology and medicine 2011;41(9):829-37.
2011: Paolo Gelosa; Gulnur Sevin; Alice Pignieri; Silvia Budelli; Laura Castiglioni; Vanessa Blanc-Guillemaud; Laurence Lerond; Elena Tremoli; Luigi Sironi
Terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, prevents hypertensive vascular hypertrophy and fibrosis.
American journal of physiology. Heart and circulatory physiology 2011;300(3):H762-8.
2010: Paolo Gelosa; Cristina Banfi; Anita Gianella; Maura Brioschi; Alice Pignieri; Elena Nobili; Laura Castiglioni; Mauro Cimino; Elena Tremoli; Luigi Sironi
Peroxisome proliferator-activated receptor {alpha} agonism prevents renal damage and the oxidative stress and inflammatory processes affecting the brains of stroke-prone rats.
The Journal of pharmacology and experimental therapeutics 2010;335(2):324-31.
2010: Paolo Gelosa; Rossana Ballerio; Cristina Banfi; Elena Nobili; Anita Gianella; Alice Pignieri; Maura Brioschi; Uliano Guerrini; Laura Castiglioni; Vanessa Blanc-Guillemaud; Laurence Lerond; Elena Tremoli; Luigi Sironi
Terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, increases survival in stroke-prone rats by preventing systemic inflammation and endothelial dysfunction: comparison with aspirin and rosuvastatin.
The Journal of pharmacology and experimental therapeutics 2010;334(1):199-205.
2010: Anita Gianella; Uliano Guerrini; Manuela Tilenni; Luigi Sironi; Giuseppina Milano; Elena Nobili; Stefania Vaga; Maurizio C Capogrossi; Elena Tremoli; Maurizio Pesce
Magnetic resonance imaging of human endothelial progenitors reveals opposite effects on vascular and muscle regeneration into ischaemic tissues.
Cardiovascular research 2010;85(3):503-13.
2009: Paolo Gelosa; Alice Pignieri; Lars Fändriks; Marc de Gasparo; Anders Hallberg; Cristina Banfi; Laura Castiglioni; Lucia Turolo; Uliano Guerrini; Elena Tremoli; Luigi Sironi
Stimulation of AT2 receptor exerts beneficial effects in stroke-prone rats: focus on renal damage.
Journal of hypertension 2009;27(12):2444-51.
2009: Paolo Gelosa; Cristina Banfi; Maura Brioschi; Elena Nobili; Anita Gianella; Uliano Guerrini; Alice Pignieri; Elena Tremoli; Luigi Sironi
S 35171 exerts protective effects in spontaneously hypertensive stroke-prone rats by preserving mitochondrial function.
European journal of pharmacology 2009;604(1-3):117-24.
2008: Luigi Sironi; Nico Mitro; Mauro Cimino; Paolo Gelosa; Uliano Guerrini; Elena Tremoli; Enrique Saez
Treatment with LXR agonists after focal cerebral ischemia prevents brain damage.
FEBS letters 2008;582(23-24):3396-400.
2008: Davide Lecca; Maria Letizia Trincavelli; Paolo Gelosa; Luigi Sironi; Paolo Ciana; Marta Fumagalli; Giovanni Villa; Claudia Verderio; Carlotta Grumelli; Uliano Guerrini; Elena Tremoli; Patrizia Rosa; Serena Cuboni; Claudia Martini; Annalisa Buffo; Mauro Cimino; Maria P Abbracchio
The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair.
PloS one 2008;3(10):e3579.
2007: Andrea Decensi; Sara Gandini; Davide Serrano; Massimiliano Cazzaniga; Maria Pizzamiglio; Fausto Antonio Maffini; Giuseppe Pelosi; Cristina Daldoss; Umberto Omodei; Harriet Johansson; Debora Macis; Matteo Lazzeroni; Mauro Penotti; Luigi Sironi; Simona Moroni; Vanda Bianco; Gabriella Rondanina; Jennifer Gjerde; Aliana Guerrieri-Gonzaga; Bernardo Bonanni
Randomized dose-ranging trial of tamoxifen at low doses in hormone replacement therapy users.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(27):4201-9.
2007: Mauro Cimino; Paolo Gelosa; Anita Gianella; Elena Nobili; Elena Tremoli; Luigi Sironi
Statins: multiple mechanisms of action in the ischemic brain.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 2007;13(3):208-13.
2007: Anita Gianella; Elena Nobili; Mauro Abbate; Carla Zoja; Paolo Gelosa; Luciana Mussoni; Stefano Bellosta; Monica Canavesi; Daniela Rottoli; Uliano Guerrini; Maura Brioschi; Cristina Banfi; Elena Tremoli; Giuseppe Remuzzi; Luigi Sironi
Rosuvastatin treatment prevents progressive kidney inflammation and fibrosis in stroke-prone rats.
The American journal of pathology 2007;170(4):1165-77.
2007: Pia Villa; Sara Triulzi; Barbara Cavalieri; Rosa Di Bitondo; Riccardo Bertini; Sara Barbera; Paolo Bigini; Tiziana Mennini; Paolo Gelosa; Elena Tremoli; Luigi Sironi; Pietro Ghezzi
The interleukin-8 (IL-8/CXCL8) receptor inhibitor reparixin improves neurological deficits and reduces long-term inflammation in permanent and transient cerebral ischemia in rats.
Molecular medicine (Cambridge, Mass.) 2007;13(3-4):125-33.
2007: Rossana Ballerio; Elisabetta Gianazza; Luciana Mussoni; Ingrid Miller; Paolo Gelosa; Uliano Guerrini; Ivano Eberini; Manfred Gemeiner; Silvia Belcredito; Elena Tremoli; Luigi Sironi
Gender differences in endothelial function and inflammatory markers along the occurrence of pathological events in stroke-prone rats.
Experimental and molecular pathology 2007;82(1):33-41.
2007: Paolo Gelosa; Mauro Cimino; Alice Pignieri; Elena Tremoli; Uliano Guerrini; Luigi Sironi
The role of HMG-CoA reductase inhibition in endothelial dysfunction and inflammation.
Vascular health and risk management 2007;3(5):567-77.
2006: Speranza Rubattu; Norbert Hubner; Ursula Ganten; Anna Evangelista; Rosita Stanzione; Emanuele Di Angelantonio; Ralph Plehm; Reika Langanki; Elisabetta Gianazza; Luigi Sironi; Giulia d'Amati; Massimo Volpe
Reciprocal congenic lines for a major stroke QTL on rat chromosome 1.
Physiological genomics 2006;27(2):108-13.
2006: Paolo Ciana; Marta Fumagalli; Maria Letizia Trincavelli; Claudia Verderio; Patrizia Rosa; Davide Lecca; Silvia Ferrario; Chiara Parravicini; Valérie Capra; Paolo Gelosa; Uliano Guerrini; Silvia Belcredito; Mauro Cimino; Luigi Sironi; Elena Tremoli; G Enrico Rovati; Claudia Martini; Maria P Abbracchio
The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor.
The EMBO journal 2006;25(19):4615-27.
2006: Luigi Sironi; Cristina Banfi; Maura Brioschi; Paolo Gelosa; Uliano Guerrini; Elena Nobili; Anita Gianella; Rodolfo Paoletti; Elena Tremoli; Mauro Cimino
Activation of NF-kB and ERK1/2 after permanent focal ischemia is abolished by simvastatin treatment.
Neurobiology of disease 2006;22(2):445-51.
2006: Simone Cristoni; Maura Brioschi; Andrea Rizzi; Luigi Sironi; Paolo Gelosa; Elena Tremoli; Luigi Rossi Bernardi; Cristina Banfi
Analysis of rosuvatatin by imaging mass spectrometry.
Rapid communications in mass spectrometry : RCM 2006;20(22):3483-7.
2005: Mauro Cimino; Walter Balduini; Silvia Carloni; Paolo Gelosa; Uliano Guerrini; Elena Tremoli; Luigi Sironi
Neuroprotective effect of simvastatin in stroke: a comparison between adult and neonatal rat models of cerebral ischemia.
Neurotoxicology 2005;26(5):929-33.
2005: Luigi Sironi; Elena Nobili; Anita Gianella; Paolo Gelosa; Elena Tremoli
Anti-inflammatory properties of drugs acting on the renin-angiotensin system.
Drugs of today (Barcelona, Spain : 1998) 2005;41(9):609-22.
2005: Diego Dolcetta; Stefano Amadio; Uliano Guerrini; Maria I Givogri; Laura Perani; Francesca Galbiati; Luigi Sironi; Ubaldo Del Carro; Maria-Grazia Roncarolo; Ernesto R Bongarzone
Myelin deterioration in Twitcher mice: motor evoked potentials and magnetic resonance imaging as in vivo monitoring tools.
Journal of neuroscience research 2005;81(4):597-604.
2005: A Lascialfari; I Zucca; Maria Asdente; Mauro Cimino; Uliano Guerrini; Rodolfo Paoletti; Elena Tremoli; V Lorusso; Luigi Sironi
Multiexponential T2-relaxation analysis in cerebrally damaged rats in the absence and presence of a gadolinium contrast agent.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2005;53(6):1326-32.
2005: Luigi Sironi; Elisabetta Gianazza; Paolo Gelosa; Uliano Guerrini; Elena Nobili; Anita Gianella; Benedetta Cremonesi; Rodolfo Paoletti; Elena Tremoli
Rosuvastatin, but not simvastatin, provides end-organ protection in stroke-prone rats by antiinflammatory effects.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(3):598-603.
2005: Anna De Antoni; Chad Pearson; Daniela Cimini; Julie C Canman; Valeria Sala; Luigi Nezi; Marina Mapelli; Luigi Sironi; Mario Faretta; Edward D Salmon; Andrea Musacchio
The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint.
Current biology : CB 2005;15(3):214-25.
2004: Luigi Sironi; Paolo Gelosa; Uliano Guerrini; Cristina Banfi; Veronica Crippa; Maura Brioschi; Elisabetta Gianazza; Elena Nobili; Anita Gianella; Marc de Gasparo; Elena Tremoli
Anti-inflammatory effects of AT1 receptor blockade provide end-organ protection in stroke-prone rats independently from blood pressure fall.
The Journal of pharmacology and experimental therapeutics 2004;311(3):989-95.
2004: Luigi Sironi; Uliano Guerrini; Elena Tremoli; Ingrid Miller; Paolo Gelosa; Alessandro Lascialfari; Ileana Zucca; Ivano Eberini; Manfred Gemeiner; Rodolfo Paoletti; Elisabetta Gianazza
Analysis of pathological events at the onset of brain damage in stroke-prone rats: a proteomics and magnetic resonance imaging approach.
Journal of neuroscience research 2004;78(1):115-22.
2004: Cristina Banfi; Luigi Sironi; Grazia De Simoni; Paolo Gelosa; Simona Barcella; Carlo Perego; Elisabetta Gianazza; Uliano Guerrini; Elena Tremoli; Luciana Mussoni
Pentoxifylline prevents spontaneous brain ischemia in stroke-prone rats.
The Journal of pharmacology and experimental therapeutics 2004;310(3):890-5.
2003: Elisabetta Gianazza; Daniela Veber; Ivano Eberini; Francesca R Buccellato; Elena Mutti; Luigi Sironi; Giuseppe Scalabrino
Cobalamin (vitamin B12)-deficiency-induced changes in the proteome of rat cerebrospinal fluid.
The Biochemical journal 2003;374(Pt 1):239-46.
2003: Walter Balduini; Erika Mazzoni; Silvia Carloni; Maria Grazia De Simoni; Carlo Perego; Luigi Sironi; Mauro Cimino
Prophylactic but not delayed administration of simvastatin protects against long-lasting cognitive and morphological consequences of neonatal hypoxic-ischemic brain injury, reduces interleukin-1beta and tumor necrosis factor-alpha mRNA induction, and does not affect endothelial nitric oxide synthase expression.
Stroke; a journal of cerebral circulation 2003;34(8):2007-12.
2003: Luigi Sironi; Anna Maria Calvio; Stefano Bellosta; Barbara Lodetti; Uliano Guerrini; Mara Monetti; Elena Tremoli; Luciana Mussoni
Endogenous proteolytic activity in a rat model of spontaneous cerebral stroke.
Brain research 2003;974(1-2):184-92.
2003: Luigi Sironi; Mauro Cimino; Uliano Guerrini; Anna Maria Calvio; Barbara Lodetti; Maria Asdente; Walter Balduini; Rodolfo Paoletti; Elena Tremoli
Treatment with statins after induction of focal ischemia in rats reduces the extent of brain damage.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(2):322-7.
2002: Sonia Eligini; Marta Brambilla; Cristina Banfi; Marina Camera; Luigi Sironi; Silvia Barbieri; Johan Auwerx; Elena Tremoli; Susanna Colli
Oxidized phospholipids inhibit cyclooxygenase-2 in human macrophages via nuclear factor-kappaB/IkappaB- and ERK2-dependent mechanisms.
Cardiovascular research 2002;55(2):406-15.
2002: Luigi Sironi; Marina Mapelli; Stefan Knapp; Anna De Antoni; Kuan-Teh Jeang; Andrea Musacchio
Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint.
The EMBO journal 2002;21(10):2496-506.
2002: Mauro Penotti; Luigi Sironi; Fabio Amicarelli; Federica Flenda; Livio Gabrielli; Michele Vignali
Surgically induced menopause and blood flow in cerebral arteries.
Fertility and sterility 2002;77(5):1086-7.
2002: Uliano Guerrini; Luigi Sironi; Elena Tremoli; Mauro Cimino; Bianca Pollo; Anna Maria Calvio; Rodolfo Paoletti; Maria Asdente
New insights into brain damage in stroke-prone rats: a nuclear magnetic imaging study.
Stroke; a journal of cerebral circulation 2002;33(3):825-30.
2001: Roberta Fraschini; Alessia Beretta; Luigi Sironi; Andrea Musacchio; Giovanna Lucchini; Simonetta Piatti
Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores.
The EMBO journal 2001;20(23):6648-59.
2001: Luigi Sironi; Marina Melixetian; Mario Faretta; Elena Prosperini; Kristian Helin; Andrea Musacchio
Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint.
The EMBO journal 2001;20(22):6371-82.
2001: Luciana Mussoni; Luigi Sironi; L Tedeschi; Anna Maria Calvio; Susanna Colli; Elena Tremoli
Magnesium inhibits arterial thrombi after vascular injury in rat: in vivo impairment of coagulation.
Thrombosis and haemostasis 2001;86(5):1292-5.
2001: Robin Wait; Elisabetta Gianazza; Ivano Eberini; Luigi Sironi; Michael J Dunn; Manfred Gemeiner; Ingrid Miller
Proteins of rat serum, urine, and cerebrospinal fluid: VI. Further protein identifications and interstrain comparison.
Electrophoresis 2001;22(14):3043-52.
2001: Mauro Penotti; Luigi Sironi; L Cannata; Paola Viganò; A Casini; Livio Gabrielli; Michele Vignali
Effects of androgen supplementation of hormone replacement therapy on the vascular reactivity of cerebral arteries.
Fertility and sterility 2001;76(2):235-40.
2001: Cristina Banfi; Per Eriksson; G Giandomenico; Luciana Mussoni; Luigi Sironi; Anders Hamsten; Elena Tremoli
Transcriptional regulation of plasminogen activator inhibitor type 1 gene by insulin: insights into the signaling pathway.
Diabetes 2001;50(7):1522-30.
2001: Luigi Sironi; Anna Maria Calvio; Lorenzo Arnaboldi; Alberto Corsini; Alessandro Parolari; Marc de Gasparo; Elena Tremoli; Luciana Mussoni
Effect of valsartan on angiotensin II-induced plasminogen activator inhibitor-1 biosynthesis in arterial smooth muscle cells.
Hypertension 2001;37(3):961-6.
2001: Luigi Sironi; Elena Tremoli; Ingrid Miller; Uliano Guerrini; Anna Maria Calvio; Ivano Eberini; Manfred Gemeiner; Maria Asdente; Rodolfo Paoletti; Elisabetta Gianazza
Acute-phase proteins before cerebral ischemia in stroke-prone rats: identification by proteomics.
Stroke; a journal of cerebral circulation 2001;32(3):753-60.
2000: Luciana Mussoni; Cristina Banfi; Luigi Sironi; M Arpaia; Elena Tremoli
Fluvastatin inhibits basal and stimulated plasminogen activator inhibitor 1, but induces tissue type plasminogen activator in cultured human endothelial cells.
Thrombosis and haemostasis 2000;84(1):59-64.
1999: Luigi Sironi; L O Molendini; C Bernabei; F Marozzi
Incidence of xenobiotics among drivers killed in single-vehicle crashes.
Forensic science international 1999;104(1):37-46.
1999: Sonia Eligini; Susanna Colli; F Basso; Luigi Sironi; Elena Tremoli
Oxidized low density lipoprotein suppresses expression of inducible cyclooxygenase in human macrophages.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(7):1719-25.
1999: Mauro Penotti; Luigi Sironi; E Castiglioni; L Miglierina; L Barletta; Livio Gabrielli; Michele Vignali
Blood flow in the internal carotid and middle cerebral arteries: effects of continuous oral conjugated equine estrogens administration with monthly progestogen supplementation on postmenopausal women.
Menopause (New York, N.Y.) 1999;6(3):225-9.
1998: Mauro Penotti; Luigi Sironi; L Miglierina; M Farina; L Barletta; Livio Gabrielli; Michele Vignali
The effect of tamoxifen and transdermal 17beta-estradiol on cerebral arterial vessels: a randomized controlled study.
American journal of obstetrics and gynecology 1998;178(4):801-5.
1996: Mauro Penotti; M Farina; Luigi Sironi; L Barletta; Livio Gabrielli; Michele Vignali
Cerebral artery blood flow in relation to age and menopausal status.
Obstetrics and gynecology 1996;88(1):106-9.
1996: Luciana Mussoni; Cristina Banfi; Luigi Sironi; Damiano Baldassarre; Elena Tremoli
Plasminogen activator inhibitor type 1 secretion by HepG2 cells: opposite effects of two fibric acid derivatives.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1996;7(4):503-5.
1996: Luigi Sironi; Luciana Mussoni; L Prati; Damiano Baldassarre; Marina Camera; Cristina Banfi; Elena Tremoli
Plasminogen activator inhibitor type-1 synthesis and mRNA expression in HepG2 cells are regulated by VLDL.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(1):89-96.
1994: Nicola Doldi; Mauro Busacca; F Bombelli; Luigi Sironi; Augusto Ferrari
Complete testicular feminization with normal gonadotropin and high androgen secretion: a case report.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 1994;8(4):255-8.
1993: Laura Belvisi; F Bombelli; Luigi Sironi; Nicola Doldi
Organ-specific autoimmunity in patients with premature ovarian failure.
Journal of endocrinological investigation 1993;16(11):889-92.
1993: Elena Tremoli; Marina Camera; P Maderna; Luigi Sironi; L Prati; Susanna Colli; F Piovella; Franco Bernini; Alberto Corsini; Luciana Mussoni
Increased synthesis of plasminogen activator inhibitor-1 by cultured human endothelial cells exposed to native and modified LDLs. An LDL receptor-independent phenomenon.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(3):338-46.
1993: Marina Camera; Susanna Colli; Alberto Corsini; P Maderna; Luciana Mussoni; L Prati; Luigi Sironi; Franco Bernini; Elena Tremoli
Effect of atherogenic lipoproteins on PAI-1 synthesis by endothelial cells.
Cytotechnology 1993;11(Suppl 1):S144-6.
1993: Marina Camera; Luciana Mussoni; P Maderna; Luigi Sironi; L Prati; Susanna Colli; Franco Bernini; Alberto Corsini; Elena Tremoli
Effect of atherogenic lipoproteins on PAI-1 synthesis by endothelial cells.
Cytotechnology 1993;11 Suppl 1():S144-6.
1992: Luciana Mussoni; L Mannucci; M Sirtori; Marina Camera; P Maderna; Luigi Sironi; Elena Tremoli
Hypertriglyceridemia and regulation of fibrinolytic activity.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1992;12(1):19-27.