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Alexander Sirotkin

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Alexander V Sirotkin; Andrej Benčo; Roland Grossmann; Monika Meszarošová; Francisco Valenzuela
Effect of inhibitor and activator of ghrelin receptor (GHS-R1a) on porcine ovarian granulosa cell functions.
Alexander V Sirotkin; Marcela Lauková; Dmitriy Ovcharenko; Pauline Brenaut; Milos Mlyncek
Identification of microRNAs controlling human ovarian cell proliferation and apoptosis.
Alexander V Sirotkin; Dmitriy Ovcharenko; Milos Mlyncek
Identification of protein kinases that control ovarian hormone release by selective siRNAs.

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All Publications

2011: Alexander V Sirotkin; Andrej Benčo; Roland Grossmann; Monika Meszarošová; Francisco Valenzuela
Effect of inhibitor and activator of ghrelin receptor (GHS-R1a) on porcine ovarian granulosa cell functions.
General and comparative endocrinology 2011;173(1):105-10.
2010: Alexander V Sirotkin; Marcela Lauková; Dmitriy Ovcharenko; Pauline Brenaut; Milos Mlyncek
Identification of microRNAs controlling human ovarian cell proliferation and apoptosis.
Journal of cellular physiology 2010;223(1):49-56.
2010: Alexander V Sirotkin; Dmitriy Ovcharenko; Milos Mlyncek
Identification of protein kinases that control ovarian hormone release by selective siRNAs.
Journal of molecular endocrinology 2010;44(1):45-53.
2009: Alexander V Sirotkin; Jan Rafay; J Kotwica
Leptin controls rabbit ovarian function in vivo and in vitro: possible interrelationships with ghrelin.
Theriogenology 2009;72(6):765-72.
2009: Alexander V Sirotkin; Dmitriy Ovcharenko; Roland Grossmann; Marcela Lauková; Milos Mlyncek
Identification of microRNAs controlling human ovarian cell steroidogenesis via a genome-scale screen.
Journal of cellular physiology 2009;219(2):415-20.
2009: Alexander V Sirotkin; Dmitriy Ovcharenko; Andrej Benco; Milos Mlyncek
Protein kinases controlling PCNA and p53 expression in human ovarian cells.
Functional & integrative genomics 2009;9(2):185-95.
2009: Alexander V Sirotkin; Ján Rafay; Ján Kotwica; Krzysztof Darlak; Francisco Valenzuela
Role of ghrelin in regulating rabbit ovarian function and the response to LH and IGF-I.
Domestic animal endocrinology 2009;36(3):162-72.
2008: E Kubovicová; Alexander V Makarevich; Juraj Pivko; Peter Chrenek; P Grafenau; L' Ríha; Alexander V Sirotkin; F Louda
Alteration in ultrastructural morphology of bovine embryos following subzonal microinjection of bovine viral diarrhea virus (BVDV).
Zygote (Cambridge, England) 2008;16(3):187-93.
2008: Alexander V Sirotkin; Maria Chrenková; Sona Nitrayová; Peter Patras; Krzysztof Darlak; Francisco Valenzuela; Leonor Pinilla; Manuel Tena-Sempere
Effects of chronic food restriction and treatments with leptin or ghrelin on different reproductive parameters of male rats.
Peptides 2008;29(8):1362-8.
2008: Alexander V Sirotkin; Roland Grossmann
Effects of ghrelin and its analogues on chicken ovarian granulosa cells.
Domestic animal endocrinology 2008;34(2):125-34.
2008: Monika Martiniaková; Radoslav Omelka; Birgit Grosskopf; Alexander V Sirotkin; Peter Chrenek
Sex-related variation in compact bone microstructure of the femoral diaphysis in juvenile rabbits.
Acta veterinaria Scandinavica 2008;50():15.
2008: Alexander V Sirotkin; P Chrenek; J Rafay; R Omelka; H Vetr; R Jurcík; B R Binder
Some endocrine traits of transgenic rabbits. I. Changes in plasma and milk hormones.
Physiological research / Academia Scientiarum Bohemoslovaca 2008;57(5):735-43.
2008: Alexander V Sirotkin; P Chrenek; K Darlak; F Valenzuela; Z Kuklová
Some endocrine traits of transgenic rabbits. II. Changes in hormone secretion and response of isolated ovarian tissue to FSH and ghrelin.
Physiological research / Academia Scientiarum Bohemoslovaca 2008;57(5):745-51.
2008: Alexander V Sirotkin; M Mlyncek; Alexander V Makarevich; I Florkovicová; L Hetényi
Leptin affects proliferation-, apoptosis- and protein kinase A-related peptides in human ovarian granulosa cells.
Physiological research / Academia Scientiarum Bohemoslovaca 2008;57(3):437-42.
2007: Alexander V Sirotkin; Roland Grossmann
Leptin directly controls proliferation, apoptosis and secretory activity of cultured chicken ovarian cells.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2007;148(2):422-9.
2007: Alexander V Sirotkin; Roland Grossmann
The role of ghrelin and some intracellular mechanisms in controlling the secretory activity of chicken ovarian cells.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2007;147(1):239-46.
2006: Alexander V Sirotkin; Roland Grossmann; M T María-Peon; J Roa; M Tena-Sempere; Sabine Klein
Novel expression and functional role of ghrelin in chicken ovary.
Molecular and cellular endocrinology 2006;257-258():15-25.
2006: Alexander V Sirotkin; Roland Grossmann
The role of protein kinase A and cyclin-dependent (CDC2) kinase in the control of basal and IGF-II-induced proliferation and secretory activity of chicken ovarian cells.
Animal reproduction science 2006;92(1-2):169-81.
2005: Alexander V Sirotkin
Control of reproductive processes by growth hormone: extra- and intracellular mechanisms.
Veterinary journal (London, England : 1997) 2005;170(3):307-17.
2005: Bozena Witek; Ewa Ochwanowska; Jan Rafay; Adam Kolataj; Peter Chrenek; Karin Suvegova; Rastislav Jurcik; Alexander V Sirotkin; Krzysztof Darlak
Effect of ghrelin on activities of some lysosomal hydrolases in rabbits.
Neuro endocrinology letters 2005;26(4):397-400.
2005: Alexander V Sirotkin; M Mlyncek; Ján Kotwica; Alexander V Makarevich; I Florkovicová; L Hetényi
Leptin directly controls secretory activity of human ovarian granulosa cells: possible inter-relationship with the IGF/IGFBP system.
Hormone research 2005;64(4):198-202.
2004: Alexander V Sirotkin; P Sanislo; Hans-Jorg Schaeffer; I Florkovicová; Ján Kotwica; Jozef Bulla; L Hetényi
Thrombopoietin regulates proliferation, apoptosis, secretory activity and intracellular messengers in porcine ovarian follicular cells: involvement of protein kinase A.
The Journal of endocrinology 2004;183(3):595-604.
2004: Alexander V Makarevich; Alexander V Sirotkin; Hans-Gottfried Genieser
Action of protein kinase A regulators on secretory activity of porcine granulosa cells in vitro.
Animal reproduction science 2004;81(1-2):125-36.
2004: Alexander V Makarevich; Alexander V Sirotkin; J Franek; HB Kwon; Jozef Bulla
The role of oxytocin, protein kinase A, and ERK-related MAP-kinase in the control of porcine ovarian follicle functions.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2004;112(2):108-14.
2003: Alexander V Sirotkin; Alexander V Makarevich; HB Kwon; Ján Kotwica
Involvement of MAP kinase in the mediation of GH action on ovarian granulosa cells.
Molecular and cellular endocrinology 2003;205(1-2):193-9.
2003: Alexander V Sirotkin; D Mertin; K Süvegová; Alexander V Makarevich; E Mikulová
Effect of GH and IGF-I treatment on reproduction, growth, and plasma hormone concentrations in domestic nutria (Myocastor coypus).
General and comparative endocrinology 2003;131(3):296-301.
2003: Alexander V Sirotkin; Iveta Florkovicova; Alexander V Makarevich; Hans-Jorg Schaeffer; Ján Kotwica; PIERRE-GUY MARNET; Pavel Sanislo
Oxytocin mediates some effects of insulin-like growth factor-I on porcine ovarian follicles.
The Journal of reproduction and development 2003;49(2):141-9.
2003: Alexander V Sirotkin; Roland Grossmann
Role of tyrosine kinase- and MAP kinase-dependent intracellular mechanisms in control of ovarian functions in the domestic fowl (Gallus domesticus) and in mediating effects of IGF-II.
The Journal of reproduction and development 2003;49(1):99-106.
2002: Alexander V Makarevich; Alexander V Sirotkin; Peter Chrenek; Jozef Bulla
Effect of epidermal growth factor (EGF) on steroid and cyclic nucleotide secretion, proliferation and ERK-related MAP-kinase in cultured rabbit granulosa cells.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2002;110(3):124-9.
2002: Alexander V Sirotkin; Alexander V Makarevich
Growth hormone can regulate functions of porcine ovarian granulosa cells through the cAMP/protein kinase A system.
Animal reproduction science 2002;70(1-2):111-26.
2002: Alexander V Sirotkin; Janka Dukesová; Juraj Pivko; Alexander V Makarevich; Alojz Kúbek
Effect of growth factors on proliferation, apoptosis and protein kinase A expression in cultured porcine cumulus oophorus cells.
Reproduction, nutrition, development 2002;42(1):35-43.
2001: Alexander V Sirotkin; Alexander V Makarevich; HB Kwon; Ján Kotwica; Jozef Bulla; L Hetényi
Do GH, IGF-I and oxytocin interact by regulating the secretory activity of porcine ovarian cells?
The Journal of endocrinology 2001;171(3):475-80.
2001: Alexander V Sirotkin; Alexander V Makarevich; M R Corkins; Ján Kotwica; HB Kwon; Jozef Bulla; L Hetényi
Secretory activity of bovine ovarian granulosa cells transfected with sense and antisense insulin-like growth factor (IGF) binding protein-3 and the response to IGF-I, GH, LH, oxytocin and oestradiol.
Journal of molecular endocrinology 2001;27(3):329-38.
2001: Alexander V Sirotkin; Alexander V Makarevich; M R Corkins; Ján Kotwica; Jozef Bulla
The transfection-induced overexpression of IGF-binding protein-4 affects the secretory activity of porcine ovarian granulosa cells and their response to hormones and IGF-I.
Journal of molecular endocrinology 2001;26(3):241-8.
2000: Alexander V Sirotkin; J Dukesová; Alexander V Makarevich; A Kubek; Jozef Bulla
Evidence that growth factors IGF-I, IGF-II and EGF can stimulate nuclear maturation of porcine oocytes via intracellular protein kinase A.
Reproduction, nutrition, development 2000;40(6):559-69.
2000: Alexander V Sirotkin; Alexander V Makarevich; Juraj Pivko; Ján Kotwica; Hans-Gottfried Genieser; Jozef Bulla
Effect of cGMP analogues and protein kinase G blocker on secretory activity, apoptosis and the cAMP/protein kinase A system in porcine ovarian granulosa cells in vitro.
The Journal of steroid biochemistry and molecular biology 2000;74(1-2):1-9.
2000: Alexander V Makarevich; Alexander V Sirotkin
Presumptive mediators of growth hormone action on insulin-like growth factor I release by porcine ovarian granulosa cells.
Biological signals and receptors 2000;9(5):248-54.
2000: Alexander V Makarevich; Alexander V Sirotkin; Peter Chrenek; Jozef Bulla; L Hetenyi
The role of IGF-I, cAMP/protein kinase A and MAP-kinase in the control of steroid secretion, cyclic nucleotide production, granulosa cell proliferation and preimplantation embryo development in rabbits.
The Journal of steroid biochemistry and molecular biology 2000;73(3-4):123-33.
2000: Alexander V Sirotkin; Alexander V Makarevich; L Hetényi
Effect of growth hormone and inhibitors of protein kinase A on IGF-I, oxytocin and progesterone release by cultured bovine granulosa cells.
Annales d'endocrinologie 2000;61(2):154-8.
2000: Alexander V Sirotkin; D Mertin; K Süvegová; Alexander V Makarevich; Hans-Gottfried Genieser; M R Luck; L V Osadchuk
Effect of restricted food intake on production, catabolism, and effects of IGF-I and cyclic nucleotides in cultured ovarian tissue of domestic nutria (Myocastor coypus).
General and comparative endocrinology 2000;117(2):207-17.
2000: Alexander V Sirotkin; Alexander V Makarevich; Hans-Gottfried Genieser; Ján Kotwica; L Hetényi
Effect of four cGMP analogues with different mechanisms of action on hormone release by porcine ovarian granulosa cells in vitro.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2000;108(3):214-9.
1999: Alexander V Sirotkin; Alexander V Makarevich
GH regulates secretory activity and apoptosis in cultured bovine granulosa cells through the activation of the cAMP/protein kinase A system.
The Journal of endocrinology 1999;163(2):317-27.
1998: Alexander V Sirotkin; Alexander V Makarevich; Ján Kotwica; PIERRE-GUY MARNET; HB Kwon; L Hetenyi
Isolated porcine ovarian follicles as a model for the study of hormone and growth factor action on ovarian secretory activity.
The Journal of endocrinology 1998;159(2):313-21.
1998: Alexander V Sirotkin; T E Taradajnik; Alexander V Makarevich; Jozef Bulla
Effect of follicular cells, IGF-I and tyrosine kinase blockers on oocyte maturation.
Animal reproduction science 1998;51(4):333-44.
1997: Alexander V Makarevich; Alexander V Sirotkin; T Taradajnik; Peter Chrenek
Effects of genistein and lavendustin on reproductive processes in domestic animals in vitro.
The Journal of steroid biochemistry and molecular biology 1997;63(4-6):329-37.
1997: Alexander V Makarevich; Alexander V Sirotkin
The involvement of the GH/IGF-I axis in the regulation of secretory activity by bovine oviduct epithelial cells.
Animal reproduction science 1997;48(2-4):197-207.
1997: Alexander V Sirotkin; Hans-Jorg Schaeffer
Direct regulation of mammalian reproductive organs by serotonin and melatonin.
The Journal of endocrinology 1997;154(1):1-5.
1997: Hans-Jorg Schaeffer; Alexander V Sirotkin
Melatonin and serotonin regulate the release of insulin-like growth factor-I, oxytocin and progesterone by cultured human granulosa cells.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1997;105(2):109-12.
1996: Alexander V Sirotkin
Inter-relationships between nonapeptide hormones and cyclic nucleotides within cultured porcine granulosa cells.
The Journal of endocrinology 1996;150(2):343-8.
1996: Alexander V Sirotkin
Direct action of growth hormone on bovine ovarian cells: effects on estradiol, oxytocin, vasopressin release by granulosa cells and on oocyte maturation and cleavage in vitro.
Annales d'endocrinologie 1996;57(3):219-24.
1996: Alexander V Sirotkin; Hans-Jorg Schaeffer; M Mlyncek; J Missik; Jozef Bulla
Oxytocin affects the release of steroids, insulin-like growth factor-I, prostaglandin F2alpha and cyclic nucleotides by human granulosa cells in vitro.
Human reproduction (Oxford, England) 1996;11(1):152-5.
1995: Hans-Jorg Schaeffer; Alexander V Sirotkin
The release of insulin-like growth factor-I by luteinized human granulosa cells in vitro: regulation by growth hormone, oxytocin, steroids and cAMP-dependent intracellular mechanisms.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1995;103(6):361-6.
1995: Hans-Jorg Schaeffer; Alexander V Sirotkin
Oxytocin regulates the secretory activity of human granulosa cells in vitro.
Advances in experimental medicine and biology 1995;395():549-50.
1995: Hans-Jorg Schaeffer; Alexander V Sirotkin
Melatonin and serotonin directly regulate oxytocin, insulin-like growth factor-I and progesterone secretion by cultured human granulosa cells.
Advances in experimental medicine and biology 1995;395():547-8.
1995: Alexander V Sirotkin; J Nitray; Jozef Bulla
Oxytocin in bovine and porcine granulosa cells. Regulation of secretion and biological effects.
Advances in experimental medicine and biology 1995;395():541-2.
1995: Alexander V Sirotkin; J Mlyncek; J Lavrincik; Jozef Bulla; L Hetenyi
The ability of steroid hormones to control cAMP and cGMP production by human granulosa cells in culture.
Cellular signalling 1995;7(1):61-5.
1994: Alexander V Sirotkin; J Nitray
Growth hormone and prolactin affect oxytocin, vasopressin, progesterone and cyclic nucleotide secretion by bovine granulosa cells in vitro.
The Journal of endocrinology 1994;143(3):417-22.
1994: Alexander V Sirotkin
Direct influence of melatonin on steroid, nonapeptide hormones, and cyclic nucleotide secretion by granulosa cells isolated from porcine ovaries.
Journal of pineal research 1994;17(3):112-7.
1994: Alexander V Sirotkin; L V Tarasenko; J Nitray; Jozef Bulla
Direct action of LH RH and its antagonist on isolated bovine granulosa cells steroidogenesis.
Journal of endocrinological investigation 1994;17(9):723-8.
1994: Alexander V Sirotkin; J Nitray
The role of cAMP- and Ca(2+)-dependent intracellular mechanisms in the control of oxytocin and vasopressin secretion by bovine ovarian granulosa cells in vitro.
Biological signals 1994;3(5):239-46.
1994: Alexander V Sirotkin; J Nitray; J Kolena; Jozef Bulla
Cooperation between LH-RH and LH in the direct action on the ovary: LH-RH stimulation of LH/hCG receptors, basal and LH-induced cAMP and cGMP release by porcine granulosa cells in vitro.
Cellular signalling 1994;6(2):135-40.
1994: Alexander V Sirotkin; J Nitray
Effects of prolactin on estrogen, cAMP and oxytocin secretion by porcine granulosa cells in vitro.
Reproduction, nutrition, development 1994;34(2):141-8.
1994: Alexander V Sirotkin; J Nitray; A Skokanova; V P Politov; J Jurcovicova; G V Marinchenko
Release of a prolactin-like substance by bovine granulosa cells in vitro: effects of ovarian steroids.
Annales d'endocrinologie 1994;55(6):279-82.
1993: Alexander V Sirotkin; J Nitray
Steroid hormones regulate cAMP and cGMP production by porcine granulosa cells in vitro.
The Journal of steroid biochemistry and molecular biology 1993;46(5):573-7.
1993: Alexander V Sirotkin; J Nitray; S V Nikolajev; S V Burov
The action of LH-releasing hormone and five analogues on oestradiol, oxytocin and vasopressin secretion by bovine granulosa cells in culture.
The Journal of endocrinology 1993;136(3):491-6.
1993: J Nitray; Alexander V Sirotkin; J Poltársky; Jozef Bulla
[The effect of recombinant somatotropin hormone on the secretion of ovarian hormones in sexually mature swine in vivo and in vitro].
Veterinární medicína 1993;38(1):53-63.
1992: Alexander V Sirotkin; J Nitray
The interrelationships between nonapeptide and steroid hormones secretion by bovine granulosa cells in vitro.
The Journal of steroid biochemistry and molecular biology 1992;43(6):529-34.
1992: J Nitray; Alexander V Sirotkin; J Poltársky
[Production of progesterone and testosterone in ovarian granulosa cells in sows after administration of nonapeptide hormones in vitro].
Veterinární medicína 1992;37(7):371-7.
1992: J Nitray; Alexander V Sirotkin; J RaFay
Effect of FSH, LH, LH-RH and arginine-vasotocin on the production of steroids, nonapeptide hormones and cGMP by rabbits granulosa cells isolated at different stages of reproductive cycle.
Endocrine regulations 1992;26(2):95-9.
1992: Alexander V Sirotkin; J Nitray
The influence of oxytocin, vasopressin and their analogues on progesterone and testosterone production by porcine granulosa cells in vitro.
Annales d'endocrinologie 1992;53(1):32-6.
1992: J Laurincík; P Kroslák; Poul Hyttel; Juraj Pivko; Alexander V Sirotkin
Bovine cumulus expansion and corona-oocyte disconnection during culture in vitro.
Reproduction, nutrition, development 1992;32(2):151-61.
1992: Alexander V Sirotkin; J Nitray; V P Politov; P Marinchenko
Prolactin-like substance secretion by granulosa cells isolated from bovine ovaries.
Annales d'endocrinologie 1992;53(5-6):196-200.
1992: J Nitray; Alexander V Sirotkin
Reciprocal control of oxytocin and cAMP production by porcine granulosa cells in vitro.
Annales d'endocrinologie 1992;53(1):28-31.
1991: J Nitray; Alexander V Sirotkin; V P Politov; G V Marincenko
[Secretory activity of ovarian granulosa cells in cows in relation to production of prolactin or prolactin-like substances in vitro].
Veterinární medicína 1991;36(10):577-83.