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Sangram Sisodia

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Placanica Lisa; Tarassishin Leonid; Yang Guangli; Peethumnongsin Erica; Kim Seong-Hun; Zheng Hui; Sisodia Sangram S; Li Yue-Ming
Pen2 and presenilin-1 modulate the dynamic equilibrium of presenilin-1 and presenilin-2 gamma-secretase complexes.
Meier Matthias; Kennedy-Darling Julia; Choi Se Hoon; Norstrom Eric M; Sisodia Sangram S; Ismagilov Rustem F
Plug-based microfluidics with defined surface chemistry to miniaturize and control aggregation of amyloidogenic peptides.
Tamboli Irfan Y; Prager Kai; Thal Dietmar R; Thelen Karin M; Dewachter Ilse; Pietrzik Claus U; St George-Hyslop Peter; Sisodia Sangram S; De Strooper Bart; Heneka Michael T; Filippov Mikhail A; Müller Ulrike; van Leuven Fred; Lütjohann Dieter; Walter Jochen
Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.

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All Publications

2009: Placanica Lisa; Tarassishin Leonid; Yang Guangli; Peethumnongsin Erica; Kim Seong-Hun; Zheng Hui; Sisodia Sangram S; Li Yue-Ming
Pen2 and presenilin-1 modulate the dynamic equilibrium of presenilin-1 and presenilin-2 gamma-secretase complexes.
The Journal of biological chemistry 2009;284(5):2967-77.
2009: Meier Matthias; Kennedy-Darling Julia; Choi Se Hoon; Norstrom Eric M; Sisodia Sangram S; Ismagilov Rustem F
Plug-based microfluidics with defined surface chemistry to miniaturize and control aggregation of amyloidogenic peptides.
Angewandte Chemie (International ed. in English) 2009;48(8):1487-9.
2008: Tamboli Irfan Y; Prager Kai; Thal Dietmar R; Thelen Karin M; Dewachter Ilse; Pietrzik Claus U; St George-Hyslop Peter; Sisodia Sangram S; De Strooper Bart; Heneka Michael T; Filippov Mikhail A; Müller Ulrike; van Leuven Fred; Lütjohann Dieter; Walter Jochen
Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(46):12097-106.
2008: Choi Se Hoon; Veeraraghavalu Karthikeyan; Lazarov Orly; Marler Seoan; Ransohoff Richard M; Ramirez Jan Marino; Sisodia Sangram S
Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation.
Neuron 2008;59(4):568-80.
2008: Vetrivel Kulandaivelu S; Zhang Xulun; Meckler Xavier; Cheng Haipeng; Lee Sungho; Gong Ping; Lopes Kryslaine O; Chen Ying; Iwata Nobuhisa; Yin Ke-Jie; Lee Jin-Moo; Parent Angèle T; Saido Takaomi C; Li Yue-Ming; Sisodia Sangram S; Thinakaran Gopal
Evidence that CD147 modulation of beta-amyloid (Abeta) levels is mediated by extracellular degradation of secreted Abeta.
The Journal of biological chemistry 2008;283(28):19489-98.
2008: Chen Qian; Nakajima Akira; Choi Se Hoon; Xiong Xiaoli; Sisodia Sangram S; Tang Ya-Ping
Adult neurogenesis is functionally associated with AD-like neurodegeneration.
Neurobiology of disease 2008;29(2):316-26.
2008: Mirnics Károly; Norstrom Eric M; Garbett Krassimira; Choi Se Hoon; Zhang Xiaoqiong; Ebert Philip; Sisodia Sangram S
Molecular signatures of neurodegeneration in the cortex of PS1/PS2 double knockout mice.
Molecular neurodegeneration 2008;3():14.
2007: Kim Jinoh; Kleizen Bertrand; Choy Regina; Thinakaran Gopal; Sisodia Sangram S; Schekman Randy W
Biogenesis of gamma-secretase early in the secretory pathway.
The Journal of cell biology 2007;179(5):951-63.
2007: Kaneko Hiroyuki; Kakita Akiyoshi; Kasuga Kensaku; Nozaki Hiroaki; Ishikawa Atsushi; Miyashita Akinori; Kuwano Ryozo; Ito Genta; Iwatsubo Takeshi; Takahashi Hitoshi; Nishizawa Masatoyo; Onodera Osamu; Sisodia Sangram S; Ikeuchi Takeshi
Enhanced accumulation of phosphorylated alpha-synuclein and elevated beta-amyloid 42/40 ratio caused by expression of the presenilin-1 deltaT440 mutant associated with familial Lewy body disease and variant Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(48):13092-7.
2007: Im Hookang; Manolopoulou Marika; Malito Enrico; Shen Yuequan; Zhao Ji; Neant-Fery Marie; Sun Ching-Yu; Meredith Stephen C; Sisodia Sangram S; Leissring Malcolm A; Tang Wei-Jen
Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE.
The Journal of biological chemistry 2007;282(35):25453-63.
2007: Lazarov Orly; Morfini Gerardo A; Pigino Gustavo; Gadadhar Archana; Chen Xiangjun; Robinson John; Ho Hanson; Brady Scott T; Sisodia Sangram S
Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(26):7011-20.
2007: Choi Se Hoon; Leight Susan N; Lee Virginia M-Y; Li Tong; Wong Philip C; Johnson Jeffrey A; Saraiva Maria J; Sisodia Sangram S
Accelerated Abeta deposition in APPswe/PS1deltaE9 mice with hemizygous deletions of TTR (transthyretin).
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(26):7006-10.
2007: Peng Chian-Yu; Yajima Hiroshi; Burns Caroline Erter; Zon Leonard I; Sisodia Sangram S; Pfaff Samuel L; Sharma Kamal
Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cord.
Neuron 2007;53(6):813-27.
2006: Hsieh Helen; Boehm Jannic; Sato Chihiro; Iwatsubo Takeshi; Tomita Taisuke; Sisodia Sangram; Malinow Roberto
AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss.
Neuron 2006;52(5):831-43.
2006: Thinakaran Gopal; Sisodia Sangram S
Presenilins and Alzheimer disease: the calcium conspiracy.
Nature neuroscience 2006;9(11):1354-5.
2006: Kim Seong-Hun; Tang Ya-Ping; Sisodia Sangram S
Abeta star: a light onto synaptic dysfunction?
Nature medicine 2006;12(7):760-1; discussion 761.
2006: Cai Dongming; Netzer William J; Zhong Minghao; Lin Yixin; Du Guangwei; Frohman Michael; Foster David A; Sisodia Sangram S; Xu Huaxi; Gorelick Fred S; Greengard Paul
Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(6):1941-6.
2006: Cai Dongming; Zhong Minghao; Wang Runsheng; Netzer William J; Shields Dennis; Zheng Hui; Sisodia Sangram S; Foster David A; Gorelick Fred S; Xu Huaxi; Greengard Paul
Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(6):1936-40.
2006: Lazarov Orly; Peterson Letia D; Peterson Daniel A; Sisodia Sangram S
Expression of a familial Alzheimer's disease-linked presenilin-1 variant enhances perforant pathway lesion-induced neuronal loss in the entorhinal cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(2):429-34.
2005: Unger Travis; Korade Zeljka; Lazarov Orly; Terrano David; Schor Nina F; Sisodia Sangram S; Mirnics Károly
Transcriptome differences between the frontal cortex and hippocampus of wild-type and humanized presenilin-1 transgenic mice.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2005;13(12):1041-51.
2005: Kim Seong-Hun; Sisodia Sangram S
Evidence that the "NF" motif in transmembrane domain 4 of presenilin 1 is critical for binding with PEN-2.
The Journal of biological chemistry 2005;280(51):41953-66.
2005: Mirnics Zeljka Korade; Yan Chaohua; Portugal Carmel; Kim Tae-Wan; Saragovi H Uri; Sisodia Sangram S; Mirnics Karoly; Schor Nina F
P75 neurotrophin receptor regulates expression of neural cell adhesion molecule 1.
Neurobiology of disease 2005;20(3):969-85.
2005: Unger Travis; Korade Zeljka; Lazarov Orly; Terrano David; Sisodia Sangram S; Mirnics Károly
True and false discovery in DNA microarray experiments: transcriptome changes in the hippocampus of presenilin 1 mutant mice.
Methods (San Diego, Calif.) 2005;37(3):261-73.
2005: Perez Sylvia E; Lazarov Orly; Koprich James B; Chen Er-Yun; Rodriguez-Menendez Virginia; Lipton Jack W; Sisodia Sangram S; Mufson Elliott J
Nigrostriatal dysfunction in familial Alzheimer's disease-linked APPswe/PS1DeltaE9 transgenic mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(44):10220-9.
2005: Vetrivel Kulandaivelu S; Cheng Haipeng; Kim Seong-Hun; Chen Ying; Barnes Natalie Y; Parent Angèle T; Sisodia Sangram S; Thinakaran Gopal
Spatial segregation of gamma-secretase and substrates in distinct membrane domains.
The Journal of biological chemistry 2005;280(27):25892-900.
2005: Lazarov Orly; Robinson John; Tang Ya-Ping; Hairston Ilana S; Korade-Mirnics Zeljka; Lee Virginia M-Y; Hersh Louis B; Sapolsky Robert M; Mirnics Karoly; Sisodia Sangram S
Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice.
Cell 2005;120(5):701-13.
2005: Lazarov Orly; Morfini Gerardo A; Lee Edward B; Farah Mohamed H; Szodorai Anita; DeBoer Scott R; Koliatsos Vassilis E; Kins Stefan; Lee Virginia M-Y; Wong Philip C; Price Donald L; Brady Scott T; Sisodia Sangram S
Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(9):2386-95.
2005: Mirnics Károly; Korade Zeljka; Arion Dominique; Lazarov Orly; Unger Travis; Macioce Melissa; Sabatini Michael; Terrano David; Douglass Katherine C; Schor Nina F; Sisodia Sangram S
Presenilin-1-dependent transcriptome changes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(6):1571-8.
2005: Parent Angèle T; Barnes Natalie Y; Taniguchi Yoshihito; Thinakaran Gopal; Sisodia Sangram S
Presenilin attenuates receptor-mediated signaling and synaptic function.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(6):1540-9.
2005: Kim Seong-Hun; Sisodia Sangram S
A sequence within the first transmembrane domain of PEN-2 is critical for PEN-2-mediated endoproteolysis of presenilin 1.
The Journal of biological chemistry 2005;280(3):1992-2001.
2004: Kim Seong-Hun; Yin Ye Ingrid; Li Yue-Ming; Sisodia Sangram S
Evidence that assembly of an active gamma-secretase complex occurs in the early compartments of the secretory pathway.
The Journal of biological chemistry 2004;279(47):48615-9.
2004: Herms Jochen; Anliker Brigitte; Heber Sabine; Ring Sabine; Fuhrmann Martin; Kretzschmar Hans; Sisodia Sangram; Müller Ulrike
Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members.
The EMBO journal 2004;23(20):4106-15.
2004: Louvi Angeliki; Sisodia Sangram S; Grove Elizabeth A
Presenilin 1 in migration and morphogenesis in the central nervous system.
Development (Cambridge, England) 2004;131(13):3093-105.
2003: Mirnics Z K; Mirnics K; Terrano D; Lewis D A; Sisodia S S; Schor N F
DNA microarray profiling of developing PS1-deficient mouse brain reveals complex and coregulated expression changes.
Molecular psychiatry 2003;8(10):863-78.
2003: Kim Seong-Hun; Ikeuchi Takeshi; Yu Chunjiang; Sisodia Sangram S
Regulated hyperaccumulation of presenilin-1 and the "gamma-secretase" complex. Evidence for differential intramembranous processing of transmembrane subatrates.
The Journal of biological chemistry 2003;278(36):33992-4002.
2003: Taniguchi Yoshihito; Kim Seong-Hun; Sisodia Sangram S
Presenilin-dependent "gamma-secretase" processing of deleted in colorectal cancer (DCC).
The Journal of biological chemistry 2003;278(33):30425-8.
2003: Kamenetz Flavio; Tomita Taisuke; Hsieh Helen; Seabrook Guy; Borchelt David; Iwatsubo Takeshi; Sisodia Sangram; Malinow Roberto
APP processing and synaptic function.
Neuron 2003;37(6):925-37.
2003: Ikeuchi Takeshi; Sisodia Sangram S
The Notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent "gamma-secretase" cleavage.
The Journal of biological chemistry 2003;278(10):7751-4.
2003: Ikeuchi Takeshi; Dolios Georgia; Kim Seong-Hun; Wang Rong; Sisodia Sangram S
Familial Alzheimer disease-linked presenilin 1 variants enhance production of both Abeta 1-40 and Abeta 1-42 peptides that are only partially sensitive to a potent aspartyl protease transition state inhibitor of "gamma-secretase".
The Journal of biological chemistry 2003;278(9):7010-8.
2003: Cai Dongming; Leem Jae Yoon; Greenfield Jeffrey P; Wang Pei; Kim Benny S; Wang Runsheng; Lopes Kryslaine O; Kim Seong-Hun; Zheng Hui; Greengard Paul; Sisodia Sangram S; Thinakaran Gopal; Xu Huaxi
Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein.
The Journal of biological chemistry 2003;278(5):3446-54.
2002: Lazarov Orly; Lee Michael; Peterson Daniel A; Sisodia Sangram S
Evidence that synaptically released beta-amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(22):9785-93.
2002: Sisodia Sangram S; St George-Hyslop Peter H
gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?
Nature reviews. Neuroscience 2002;3(4):281-90.
2002: Borchelt David R; Lee Michael K; Gonzales Victoria; Slunt Hilda H; Ratovitski Tamara; Jenkins Nancy A; Copeland Neal G; Price Donald L; Sisodia Sangram S
Accumulation of proteolytic fragments of mutant presenilin 1 and accelerated amyloid deposition are co-regulated in transgenic mice.
Neurobiology of aging 2002;23(2):171-7.
2002: Sisodia Sangram S
Biomedicine. A cargo receptor mystery APParently solved?
Science (New York, N.Y.) 2002;295(5556):805-7.
2002: Mirinics Zeljka Korade; Calafat Jero; Udby Lene; Lovelock Josh; Kjeldsen Lars; Rothermund Kristi; Sisodia Sangram S; Borregaard Niels; Corey Seth J
Identification of the presenilins in hematopoietic cells with localization of presenilin 1 to neutrophil and platelet granules.
Blood cells, molecules & diseases 2002;28(1):28-38.
2002: Kalback Walter; Watson M Desiree; Kokjohn Tyler A; Kuo Yu-Min; Weiss Nicole; Luehrs Dean C; Lopez John; Brune Daniel; Sisodia Sangram S; Staufenbiel Matthias; Emmerling Mark; Roher Alex E
APP transgenic mice Tg2576 accumulate Abeta peptides that are distinct from the chemically modified and insoluble peptides deposited in Alzheimer's disease senile plaques.
Biochemistry 2002;41(3):922-8.
2002: Kim Seong-Hun; Creemers John W M; Chu Su; Thinakaran Gopal; Sisodia Sangram S
Proteolytic processing of familial British dementia-associated BRI variants: evidence for enhanced intracellular accumulation of amyloidogenic peptides.
The Journal of biological chemistry 2002;277(3):1872-7.
2002: Ikeuchi Takesh; Sisodia Sangram S
Cell-free generation of the notch1 intracellular domain (NICD) and APP-CTfgamma: evidence for distinct intramembranous "gamma-secretase" activities.
Neuromolecular medicine 2002;1(1):43-54.
2001: Feng R; Rampon C; Tang Y P; Shrom D; Jin J; Kyin M; Sopher B; Miller M W; Ware C B; Martin G M; Kim S H; Langdon R B; Sisodia S S; Tsien J Z
Deficient neurogenesis in forebrain-specific presenilin-1 knockout mice is associated with reduced clearance of hippocampal memory traces.
Neuron 2001;32(5):911-26.
2001: Sisodia S S; Annaert W; Kim S H; De Strooper B
Gamma-secretase: never more enigmatic.
Trends in neurosciences 2001;24(11 Suppl):S2-6.
2001: Yu C; Kim S H; Ikeuchi T; Xu H; Gasparini L; Wang R; Sisodia S S
Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment gamma. Evidence for distinct mechanisms involved in gamma -secretase processing of the APP and Notch1 transmembrane domains.
The Journal of biological chemistry 2001;276(47):43756-60.
2001: Kim S H; Leem J Y; Lah J J; Slunt H H; Levey A I; Thinakaran G; Sisodia S S
Multiple effects of aspartate mutant presenilin 1 on the processing and trafficking of amyloid precursor protein.
The Journal of biological chemistry 2001;276(46):43343-50.
2001: Benjannet S; Elagoz A; Wickham L; Mamarbachi M; Munzer J S; Basak A; Lazure C; Cromlish J A; Sisodia S; Checler F; Chrétien M; Seidah N G
Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production.
The Journal of biological chemistry 2001;276(14):10879-87.
2000: Martys-Zage J L; Kim S H; Berechid B; Bingham S J; Chu S; Sklar J; Nye J; Sisodia S S
Requirement for presenilin 1 in facilitating lagged 2-mediated endoproteolysis and signaling of notch 1.
Journal of molecular neuroscience : MN 2000;15(3):189-204.
2000: Sato N; Urano F; Yoon Leem J; Kim S H; Li M; Donoviel D; Bernstein A; Lee A S; Ron D; Veselits M L; Sisodia S S; Thinakaran G
Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression.
Nature cell biology 2000;2(12):863-70.
2000: Takahashi M; Doré S; Ferris C D; Tomita T; Sawa A; Wolosker H; Borchelt D R; Iwatsubo T; Kim S H; Thinakaran G; Sisodia S S; Snyder S H
Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease.
Neuron 2000;28(2):461-73.
2000: Heber S; Herms J; Gajic V; Hainfellner J; Aguzzi A; Rülicke T; von Kretzschmar H; von Koch C; Sisodia S; Tremml P; Lipp H P; Wolfer D P; Müller U
Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(21):7951-63.
2000: Sisodia S S
Neuroscience. An accomplice for gamma-secretase brought into focus.
Science (New York, N.Y.) 2000;289(5488):2296-7.
2000: Kim S H; Lah J J; Thinakaran G; Levey A; Sisodia S S
Subcellular localization of presenilins: association with a unique membrane pool in cultured cells.
Neurobiology of disease 2000;7(2):99-117.
2000: Zaman S H; Parent A; Laskey A; Lee M K; Borchelt D R; Sisodia S S; Malinow R
Enhanced synaptic potentiation in transgenic mice expressing presenilin 1 familial Alzheimer's disease mutation is normalized with a benzodiazepine.
Neurobiology of disease 2000;7(1):54-63.
2000: Kim S H; Wang R; Gordon D J; Bass J; Steiner D F; Thinakaran G; Lynn D G; Meredith S C; Sisodia S S
Familial British dementia: expression and metabolism of BRI.
Annals of the New York Academy of Sciences 2000;920():93-9.
2000: Price D L; Wong P C; Markowska A L; Lee M K; Thinakaren G; Cleveland D W; Sisodia S S; Borchelt D R
The value of transgenic models for the study of neurodegenerative diseases.
Annals of the New York Academy of Sciences 2000;920():179-91.
1999: Berechid B E; Thinakaran G; Wong P C; Sisodia S S; Nye J S
Lack of requirement for presenilin1 in Notch1 signaling.
Current biology : CB 1999;9(24):1493-6.
1999: Sisodia S S
Alzheimer's disease: perspectives for the new millennium.
The Journal of clinical investigation 1999;104(9):1169-70.
1999: Kim S H; Wang R; Gordon D J; Bass J; Steiner D F; Lynn D G; Thinakaran G; Meredith S C; Sisodia S S
Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia.
Nature neuroscience 1999;2(11):984-8.
1999: Li X F; Thinakaran G; Sisodia S S; Yu F S
Amyloid precursor-like protein 2 promotes cell migration toward fibronectin and collagen IV.
The Journal of biological chemistry 1999;274(38):27249-56.
1999: Lamb B T; Bardel K A; Kulnane L S; Anderson J J; Holtz G; Wagner S L; Sisodia S S; Hoeger E J
Amyloid production and deposition in mutant amyloid precursor protein and presenilin-1 yeast artificial chromosome transgenic mice.
Nature neuroscience 1999;2(8):695-7.
1999: Sisodia S S; Kim S H; Thinakaran G
Function and dysfunction of the presenilins.
American journal of human genetics 1999;65(1):7-12.
1999: Kang D E; Soriano S; Frosch M P; Collins T; Naruse S; Sisodia S S; Leibowitz G; Levine F; Koo E H
Presenilin 1 facilitates the constitutive turnover of beta-catenin: differential activity of Alzheimer's disease-linked PS1 mutants in the beta-catenin-signaling pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(11):4229-37.
1999: Parent A; Linden D J; Sisodia S S; Borchelt D R
Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1.
Neurobiology of disease 1999;6(1):56-62.
1999: Greenfield J P; Tsai J; Gouras G K; Hai B; Thinakaran G; Checler F; Sisodia S S; Greengard P; Xu H
Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(2):742-7.
1998: Buxbaum J D; Thinakaran G; Koliatsos V; O'Callahan J; Slunt H H; Price D L; Sisodia S S
Alzheimer amyloid protein precursor in the rat hippocampus: transport and processing through the perforant path.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(23):9629-37.
1998: Naruse S; Thinakaran G; Luo J J; Kusiak J W; Tomita T; Iwatsubo T; Qian X; Ginty D D; Price D L; Borchelt D R; Wong P C; Sisodia S S
Effects of PS1 deficiency on membrane protein trafficking in neurons.
Neuron 1998;21(5):1213-21.
1998: Price D L; Sisodia S S; Borchelt D R
Genetic neurodegenerative diseases: the human illness and transgenic models.
Science (New York, N.Y.) 1998;282(5391):1079-83.
1998: Borchelt D R; Wong P C; Sisodia S S; Price D L
Transgenic mouse models of Alzheimer's disease and amyotrophic lateral sclerosis.
Brain pathology (Zurich, Switzerland) 1998;8(4):735-57.
1998: Sisodia S S
Nuclear inclusions in glutamine repeat disorders: are they pernicious, coincidental, or beneficial?
Cell 1998;95(1):1-4.
1998: Sisodia S S; Gallagher M
A role for the beta-amyloid precursor protein in memory?
Proceedings of the National Academy of Sciences of the United States of America 1998;95(21):12074-6.
1998: Tam A; Nouvet F J; Fujimura-Kamada K; Slunt H; Sisodia S S; Michaelis S
Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing.
The Journal of cell biology 1998;142(3):635-49.
1998: Price D L; Sisodia S S; Borchelt D R
Alzheimer disease--when and why?
Nature genetics 1998;19(4):314-6.
1998: Borchelt D R; Wong P C; Becher M W; Pardo C A; Lee M K; Xu Z S; Thinakaran G; Jenkins N A; Copeland N G; Sisodia S S; Cleveland D W; Price D L; Hoffman P N
Axonal transport of mutant superoxide dismutase 1 and focal axonal abnormalities in the proximal axons of transgenic mice.
Neurobiology of disease 1998;5(1):27-35.
1998: Lyckman A W; Confaloni A M; Thinakaran G; Sisodia S S; Moya K L
Post-translational processing and turnover kinetics of presynaptically targeted amyloid precursor superfamily proteins in the central nervous system.
The Journal of biological chemistry 1998;273(18):11100-6.
1998: Thinakaran G; Regard J B; Bouton C M; Harris C L; Price D L; Borchelt D R; Sisodia S S
Stable association of presenilin derivatives and absence of presenilin interactions with APP.
Neurobiology of disease 1998;4(6):438-53.
1998: Xu H; Gouras G K; Greenfield J P; Vincent B; Naslund J; Mazzarelli L; Fried G; Jovanovic J N; Seeger M; Relkin N R; Liao F; Checler F; Buxbaum J D; Chait B T; Thinakaran G; Sisodia S S; Wang R; Greengard P; Gandy S
Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides.
Nature medicine 1998;4(4):447-51.
1998: Davis J A; Naruse S; Chen H; Eckman C; Younkin S; Price D L; Borchelt D R; Sisodia S S; Wong P C
An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos.
Neuron 1998;20(3):603-9.
1998: Guo J; Thinakaran G; Guo Y; Sisodia S S; Yu F X
A role for amyloid precursor-like protein 2 in corneal epithelial wound healing.
Investigative ophthalmology & visual science 1998;39(2):292-300.
1998: Wong P C; Borchelt D R; Lee M K; Pardo C A; Thinakaran G; Martin L J; Sisodia S S; Price D L
Familial amyotrophic lateral sclerosis and Alzheimer's disease. Transgenic models.
Advances in experimental medicine and biology 1998;446():145-59.
1998: Price D L; Tanzi R E; Borchelt D R; Sisodia S S
Alzheimer's disease: genetic studies and transgenic models.
Annual review of genetics 1998;32():461-93.
1998: Price D L; Sisodia S S
Mutant genes in familial Alzheimer's disease and transgenic models.
Annual review of neuroscience 1998;21():479-505.
1997: Bergin A; Kim G; Price D L; Sisodia S S; Lee M K; Rabin B A
Identification and characterization of a mouse homologue of the spinal muscular atrophy-determining gene, survival motor neuron.
Gene 1997;204(1-2):47-53.
1997: von Koch C S; Zheng H; Chen H; Trumbauer M; Thinakaran G; van der Ploeg L H; Price D L; Sisodia S S
Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice.
Neurobiology of aging 1997;18(6):661-9.
1997: Thinakaran G; Harris C L; Ratovitski T; Davenport F; Slunt H H; Price D L; Borchelt D R; Sisodia S S
Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors.
The Journal of biological chemistry 1997;272(45):28415-22.
1997: Borchelt D R; Ratovitski T; van Lare J; Lee M K; Gonzales V; Jenkins N A; Copeland N G; Price D L; Sisodia S S
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.
Neuron 1997;19(4):939-45.
1997: Price D L; Wong P C; Borchelt D R; Pardo C A; Thinakaran G; Doan A P; Lee M K; Martin L J; Sisodia S S
Amyotrophic lateral sclerosis and Alzheimer disease. Lessons from model systems.
Revue neurologique 1997;153(8-9):484-95.
1997: Ratovitski T; Slunt H H; Thinakaran G; Price D L; Sisodia S S; Borchelt D R
Endoproteolytic processing and stabilization of wild-type and mutant presenilin.
The Journal of biological chemistry 1997;272(39):24536-41.
1997: Lamb B T; Call L M; Slunt H H; Bardel K A; Lawler A M; Eckman C B; Younkin S G; Holtz G; Wagner S L; Price D L; Sisodia S S; Gearhart J D
Altered metabolism of familial Alzheimer's disease-linked amyloid precursor protein variants in yeast artificial chromosome transgenic mice.
Human molecular genetics 1997;6(9):1535-41.
1997: Lee M K; Borchelt D R; Kim G; Thinakaran G; Slunt H H; Ratovitski T; Martin L J; Kittur A; Gandy S; Levey A I; Jenkins N; Copeland N; Price D L; Sisodia S S
Hyperaccumulation of FAD-linked presenilin 1 variants in vivo.
Nature medicine 1997;3(7):756-60.
1997: Hendriks L; Thinakaran G; Harris C L; De Jonghe C; Martin J J; Sisodia S S; Van Broeckhoven C
Processing of presenilin 1 in brains of patients with Alzheimer's disease and controls.
Neuroreport 1997;8(7):1717-21.
1997: Wong P C; Zheng H; Chen H; Becher M W; Sirinathsinghji D J; Trumbauer M E; Chen H Y; Price D L; Van der Ploeg L H; Sisodia S S
Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm.
Nature 1997;387(6630):288-92.
1997: Seeger M; Nordstedt C; Petanceska S; Kovacs D M; Gouras G K; Hahne S; Fraser P; Levesque L; Czernik A J; George-Hyslop P S; Sisodia S S; Thinakaran G; Tanzi R E; Greengard P; Gandy S
Evidence for phosphorylation and oligomeric assembly of presenilin 1.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(10):5090-4.
1997: Li H L; Roch J M; Sundsmo M; Otero D; Sisodia S; Thomas R; Saitoh T
Defective neurite extension is caused by a mutation in amyloid beta/A4 (A beta) protein precursor found in familial Alzheimer's disease.
Journal of neurobiology 1997;32(5):469-80.
1997: Xu H; Sweeney D; Wang R; Thinakaran G; Lo A C; Sisodia S S; Greengard P; Gandy S
Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3748-52.
1997: Bruijn L I; Becher M W; Lee M K; Anderson K L; Jenkins N A; Copeland N G; Sisodia S S; Rothstein J D; Borchelt D R; Price D L; Cleveland D W
ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.
Neuron 1997;18(2):327-38.
1997: Zhao B; Chrest F J; Horton W E; Sisodia S S; Kusiak J W
Expression of mutant amyloid precursor proteins induces apoptosis in PC12 cells.
Journal of neuroscience research 1997;47(3):253-63.
1997: Walter J; Capell A; Hung A Y; Langen H; Schnölzer M; Thinakaran G; Sisodia S S; Selkoe D J; Haass C
Ectodomain phosphorylation of beta-amyloid precursor protein at two distinct cellular locations.
The Journal of biological chemistry 1997;272(3):1896-903.
1997: Marquez-Sterling N R; Lo A C; Sisodia S S; Koo E H
Trafficking of cell-surface beta-amyloid precursor protein: evidence that a sorting intermediate participates in synaptic vesicle recycling.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(1):140-51.
1996: Borchelt D R; Davis J; Fischer M; Lee M K; Slunt H H; Ratovitsky T; Regard J; Copeland N G; Jenkins N A; Sisodia S S; Price D L
A vector for expressing foreign genes in the brains and hearts of transgenic mice.
Genetic analysis : biomolecular engineering 1996;13(6):159-63.
1996: Levitan D; Doyle T G; Brousseau D; Lee M K; Thinakaran G; Slunt H H; Sisodia S S; Greenwald I
Assessment of normal and mutant human presenilin function in Caenorhabditis elegans.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(25):14940-4.
1996: Wang R; Sweeney D; Gandy S E; Sisodia S S
The profile of soluble amyloid beta protein in cultured cell media. Detection and quantification of amyloid beta protein and variants by immunoprecipitation-mass spectrometry.
The Journal of biological chemistry 1996;271(50):31894-902.
1996: Lee M K; Slunt H H; Martin L J; Thinakaran G; Kim G; Gandy S E; Seeger M; Koo E; Price D L; Sisodia S S
Expression of presenilin 1 and 2 (PS1 and PS2) in human and murine tissues.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(23):7513-25.
1996: Doan A; Thinakaran G; Borchelt D R; Slunt H H; Ratovitsky T; Podlisny M; Selkoe D J; Seeger M; Gandy S E; Price D L; Sisodia S S
Protein topology of presenilin 1.
Neuron 1996;17(5):1023-30.
1996: Borchelt D R; Thinakaran G; Eckman C B; Lee M K; Davenport F; Ratovitsky T; Prada C M; Kim G; Seekins S; Yager D; Slunt H H; Wang R; Seeger M; Levey A I; Gandy S E; Copeland N G; Jenkins N A; Price D L; Younkin S G; Sisodia S S
Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo.
Neuron 1996;17(5):1005-13.
1996: Price D L; Becher M W; Wong P C; Borchelt D R; Lee M K; Sisodia S S
Inherited neurodegenerative diseases and transgenic models.
Brain pathology (Zurich, Switzerland) 1996;6(4):467-80.
1996: Lee M K; Borchelt D R; Wong P C; Sisodia S S; Price D L
Transgenic models of neurodegenerative diseases.
Current opinion in neurobiology 1996;6(5):651-60.
1996: Bressler S L; Gray M D; Sopher B L; Hu Q; Hearn M G; Pham D G; Dinulos M B; Fukuchi K; Sisodia S S; Miller M A; Disteche C M; Martin G M
cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein.
Human molecular genetics 1996;5(10):1589-98.
1996: Crain B J; Hu W; Sze C I; Slunt H H; Koo E H; Price D L; Thinakaran G; Sisodia S S
Expression and distribution of amyloid precursor protein-like protein-2 in Alzheimer's disease and in normal brain.
The American journal of pathology 1996;149(4):1087-95.
1996: Cleveland D W; Bruijn L I; Wong P C; Marszalek J R; Vechio J D; Lee M K; Xu X S; Borchelt D R; Sisodia S S; Price D L
Mechanisms of selective motor neuron death in transgenic mouse models of motor neuron disease.
Neurology 1996;47(4 Suppl 2):S54-61; discussion S61-2.
1996: Calingasan N Y; Gandy S E; Baker H; Sheu K F; Smith J D; Lamb B T; Gearhart J D; Buxbaum J D; Harper C; Selkoe D J; Price D L; Sisodia S S; Gibson G E
Novel neuritic clusters with accumulations of amyloid precursor protein and amyloid precursor-like protein 2 immunoreactivity in brain regions damaged by thiamine deficiency.
The American journal of pathology 1996;149(3):1063-71.
1996: Borchelt D R; Sisodia S S
Loss of functional prion protein: a role in prion disorders?
Chemistry & biology 1996;3(8):619-21.
1996: Thinakaran G; Borchelt D R; Lee M K; Slunt H H; Spitzer L; Kim G; Ratovitsky T; Davenport F; Nordstedt C; Seeger M; Hardy J; Levey A I; Gandy S E; Jenkins N A; Copeland N G; Price D L; Sisodia S S
Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo.
Neuron 1996;17(1):181-90.
1996: Thinakaran G; Teplow D B; Siman R; Greenberg B; Sisodia S S
Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus.
The Journal of biological chemistry 1996;271(16):9390-7.
1996: Sisodia S S; Thinakaran G; Slunt H H; Kitt C A; Von Koch C S; Reed R R; Zheng H; Price D L
Studies on the metabolism and biological function of APLP2.
Annals of the New York Academy of Sciences 1996;777():77-81.
1996: Zheng H; Jiang M; Trumbauer M E; Hopkins R; Sirinathsinghji D J; Stevens K A; Conner M W; Slunt H H; Sisodia S S; Chen H Y; Van der Ploeg L H
Mice deficient for the amyloid precursor protein gene.
Annals of the New York Academy of Sciences 1996;777():421-6.
1996: Price D L; Borchelt D R; Wong P C; Pardo C A; Thinakaran G; Lee M K; Cleveland D W; Sisodia S S
Neurodegenerative diseases and model systems.
Cold Spring Harbor symposia on quantitative biology 1996;61():725-38.
1996: Price D L; Koliatsos V E; Wong P C; Pardo C A; Borchelt D R; Lee M K; Cleveland D W; Griffin J W; Hoffman P N; Cork L C; Sisodia S S
Motor neuron disease and model systems: aetiologies, mechanisms and therapies.
Ciba Foundation symposium 1996;196():3-13; discussion 13-7.
1995: von Koch C S; Lahiri D K; Mammen A L; Copeland N G; Gilbert D J; Jenkins N A; Sisodia S
The mouse APLP2 gene. Chromosomal localization and promoter characterization.
The Journal of biological chemistry 1995;270(43):25475-80.
1995: Reeves R H; Irving N G; Moran T H; Wohn A; Kitt C; Sisodia S S; Schmidt C; Bronson R T; Davisson M T
A mouse model for Down syndrome exhibits learning and behaviour deficits.
Nature genetics 1995;11(2):177-84.
1995: Price D L; Sisodia S S; Gandy S E
Amyloid beta amyloidosis in Alzheimer's disease.
Current opinion in neurology 1995;8(4):268-74.
1995: Thinakaran G; Slunt H H; Sisodia S S
Novel regulation of chondroitin sulfate glycosaminoglycan modification of amyloid precursor protein and its homologue, APLP2.
The Journal of biological chemistry 1995;270(28):16522-5.
1995: Wong P C; Pardo C A; Borchelt D R; Lee M K; Copeland N G; Jenkins N A; Sisodia S S; Cleveland D W; Price D L
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria.
Neuron 1995;14(6):1105-16.
1995: Lo A C; Thinakaran G; Slunt H H; Sisodia S S
Metabolism of the amyloid precursor-like protein 2 in MDCK cells. Polarized trafficking occurs independent of the chondroitin sulfate glycosaminoglycan chain.
The Journal of biological chemistry 1995;270(21):12641-5.
1995: Sisodia S S; Price D L
Role of the beta-amyloid protein in Alzheimer's disease.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(5):366-70.
1995: Rabizadeh S; Gralla E B; Borchelt D R; Gwinn R; Valentine J S; Sisodia S; Wong P; Lee M; Hahn H; Bredesen D E
Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):3024-8.
1995: Lai A; Sisodia S S; Trowbridge I S
Characterization of sorting signals in the beta-amyloid precursor protein cytoplasmic domain.
The Journal of biological chemistry 1995;270(8):3565-73.
1995: Pardo C A; Xu Z; Borchelt D R; Price D L; Sisodia S S; Cleveland D W
Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(4):954-8.
1995: Borchelt D R; Guarnieri M; Wong P C; Lee M K; Slunt H S; Xu Z S; Sisodia S S; Price D L; Cleveland D W
Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function.
The Journal of biological chemistry 1995;270(7):3234-8.
1995: Zhao B; Sisodia S S; Kusiak J W
Altered processing of a mutant amyloid precursor protein in neuronal and endothelial cells.
Journal of neuroscience research 1995;40(2):261-8.
1995: Sisodia S S; Martin L J; Walker L C; Borchelt D R; Price D L
Cellular and molecular biology of Alzheimer's disease and animal models.
Neuroimaging clinics of North America 1995;5(1):59-68.
1994: Lo A C; Haass C; Wagner S L; Teplow D B; Sisodia S S
Metabolism of the "Swedish" amyloid precursor protein variant in Madin-Darby canine kidney cells.
The Journal of biological chemistry 1994;269(49):30966-73.
1994: Van Nostrand W E; Schmaier A H; Neiditch B R; Siegel R S; Raschke W C; Sisodia S S; Wagner S L
Expression, purification, and characterization of the Kunitz-type proteinase inhibitor domain of the amyloid beta-protein precursor-like protein-2.
Biochimica et biophysica acta 1994;1209(2):165-70.
1994: Thinakaran G; Sisodia S S
Amyloid precursor-like protein 2 (APLP2) is modified by the addition of chondroitin sulfate glycosaminoglycan at a single site.
The Journal of biological chemistry 1994;269(35):22099-104.
1994: Borchelt D R; Lee M K; Slunt H S; Guarnieri M; Xu Z S; Wong P C; Brown R H; Price D L; Sisodia S S; Cleveland D W
Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(17):8292-6.
1994: Borchelt D R; Koliatsos V E; Guarnieri M; Pardo C A; Sisodia S S; Price D L
Rapid anterograde axonal transport of the cellular prion glycoprotein in the peripheral and central nervous systems.
The Journal of biological chemistry 1994;269(20):14711-4.
1994: Slunt H H; Thinakaran G; Von Koch C; Lo A C; Tanzi R E; Sisodia S S
Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP).
The Journal of biological chemistry 1994;269(4):2637-44.
1994: Price D L; Sisodia S S
Cellular and molecular biology of Alzheimer's disease and animal models.
Annual review of medicine 1994;45():435-46.
1994: Sisodia S S
Cellular and molecular genetic approaches in Alzheimer's disease.
Neurobiology of aging 1994;15 Suppl 2():S135-7.
1993: da Cruz e Silva O A; Iverfeldt K; Oltersdorf T; Sinha S; Lieberburg I; Ramabhadran T V; Suzuki T; Sisodia S S; Gandy S; Greengard P
Regulated cleavage of Alzheimer beta-amyloid precursor protein in the absence of the cytoplasmic tail.
Neuroscience 1993;57(4):873-7.
1993: Wasco W; Gurubhagavatula S; Paradis M D; Romano D M; Sisodia S S; Hyman B T; Neve R L; Tanzi R E
Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor.
Nature genetics 1993;5(1):95-100.
1993: Lamb B T; Sisodia S S; Lawler A M; Slunt H H; Kitt C A; Kearns W G; Pearson P L; Price D L; Gearhart J D
Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice [corrected]
Nature genetics 1993;5(1):22-30.
1993: Sisodia S S; Koo E H; Hoffman P N; Perry G; Price D L
Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(7):3136-42.
1993: Price D L; Borchelt D R; Sisodia S S
Alzheimer disease and the prion disorders amyloid beta-protein and prion protein amyloidoses.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(14):6381-4.
1992: Sisodia S S
Secretion of the beta-amyloid precursor protein.
Annals of the New York Academy of Sciences 1992;674():53-7.
1992: Price D L; Martin L J; Clatterbuck R E; Koliatsos V E; Sisodia S S; Walker L C; Cork L C
Neuronal degeneration in human diseases and animal models.
Journal of neurobiology 1992;23(9):1277-94.
1992: Sisodia S S; Price D L
Amyloidogenesis in Alzheimer's disease: basic biology and animal models.
Current opinion in neurobiology 1992;2(5):648-52.
1992: Price D L; Walker L C; Martin L J; Sisodia S S
Amyloidosis in aging and Alzheimer's disease.
The American journal of pathology 1992;141(4):767-72.
1992: Price D L; Borchelt D R; Walker L C; Sisodia S S
Toxicity of synthetic A beta peptides and modeling of Alzheimer's disease.
Neurobiology of aging 1992;13(5):623-5.
1992: Sisodia S S
Beta-amyloid precursor protein cleavage by a membrane-bound protease.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(13):6075-9.
1992: Price D L; Martin L J; Sisodia S S; Walker L C; Cork L C
Alzheimer's disease-type brain abnormalities in animal models.
Progress in clinical and biological research 1992;379():271-87.
1991: Goedert M; Sisodia S S; Price D L
Neurofibrillary tangles and beta-amyloid deposits in Alzheimer's disease.
Current opinion in neurobiology 1991;1(3):441-7.
1991: Wang R; Meschia J F; Cotter R J; Sisodia S S
Secretion of the beta/A4 amyloid precursor protein. Identification of a cleavage site in cultured mammalian cells.
The Journal of biological chemistry 1991;266(25):16960-4.
1991: Price D L; Martin L J; Sisodia S S; Wagster M V; Koo E H; Walker L C; Koliatsos V E; Cork L C
Aged non-human primates: an animal model of age-associated neurodegenerative disease.
Brain pathology (Zurich, Switzerland) 1991;1(4):287-96.
1991: Martin L J; Sisodia S S; Koo E H; Cork L C; Dellovade T L; Weidemann A; Beyreuther K; Masters C; Price D L
Amyloid precursor protein in aged nonhuman primates.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(4):1461-5.
1991: Price D L; Koliatsos V E; Sisodia S S; Koo E H; Martin L J; Walker L C; Appelgate M D; Cork L C
Amyloid-related proteins and nerve growth factor in Alzheimer's disease and animal models.
Clinical neuropharmacology 1991;14 Suppl 1():S9-14.
1991: Abraham C R; Razzaboni B L; Sisodia S S; Koo E H; Price D L; Van Nostrand W E; Papastoitsis G
Studies on the proteolytic degradation of the beta-protein precursor by proteases purified from Alzheimer's disease brain.
Annals of the New York Academy of Sciences 1991;640():161-5.
1990: Sisodia S S; Koo E H; Beyreuther K; Unterbeck A; Price D L
Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing.
Science (New York, N.Y.) 1990;248(4954):492-5.
1990: Koo E H; Sisodia S S; Archer D R; Martin L J; Weidemann A; Beyreuther K; Fischer P; Masters C L; Price D L
Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(4):1561-5.
1990: Koo E H; Sisodia S S; Cork L C; Unterbeck A; Bayney R M; Price D L
Differential expression of amyloid precursor protein mRNAs in cases of Alzheimer's disease and in aged nonhuman primates.
Neuron 1990;4(1):97-104.
1990: Sisodia S S; Gay D A; Cleveland D W
In vivo discrimination among beta-tubulin isotypes: selective degradation of a type IV beta-tubulin isotype following overexpression in cultured animal cells.
The New biologist 1990;2(1):66-76.
1990: Price D L; Sisodia S S; Koo E H; Muma N A; Kitt C A; Walker L C; Martin L J; Troncoso J C; Griffin J W; Hoffman P N
Neuronal disorders: studies of animal models and human diseases.
Toxicologic pathology 1990;18(1 Pt 2):128-37.
1990: Price D L; Koo E H; Sisodia S S; Martin L J; Koliatsos V E; Muma N A; Walker L C; Cork L C
Neuronal responses to injury and aging: lessons from animal models.
Progress in brain research 1990;86():297-308.
1989: Gay D A; Sisodia S S; Cleveland D W
Autoregulatory control of beta-tubulin mRNA stability is linked to translation elongation.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(15):5763-7.
1987: Gabriel A; Sisodia S S; Cleveland D W
Evidence of discontinuous transcription in the trypanosomatid Crithidia fasciculata.
The Journal of biological chemistry 1987;262(33):16192-9.
1987: Sisodia S S; Sollner-Webb B; Cleveland D W
Specificity of RNA maturation pathways: RNAs transcribed by RNA polymerase III are not substrates for splicing or polyadenylation.
Molecular and cellular biology 1987;7(10):3602-12.
1987: Sisodia S S; Cleveland D W; Sollner-Webb B
A combination of RNase H and S1 nuclease circumvents an artefact inherent to conventional S1 analysis of RNA splicing.
Nucleic acids research 1987;15(5):1995-2011.

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