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Jacob Sivak

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Mehdi Rahimi; Jacob G Sivak; Hyun-Yi Youn; David J McCanna; Susan R Mikkelsen
Application of cyclic biamperometry to viability and cytotoxicity assessment in human corneal epithelial cells.
Hyun-Yi Youn; David J McCanna; Jacob G Sivak; Lyndon Jones
In vitro ultraviolet-induced damage in human corneal, lens, and retinal pigment epithelial cells.
Jacob G Sivak
The Charles F. Prentice award lecture 2009: Crystalline lens research and serendipity in science.

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All Publications

2013: Mehdi Rahimi; Jacob G Sivak; Hyun-Yi Youn; David J McCanna; Susan R Mikkelsen
Application of cyclic biamperometry to viability and cytotoxicity assessment in human corneal epithelial cells.
Analytical and bioanalytical chemistry 2013;405(14):4975-9.
2011: Hyun-Yi Youn; David J McCanna; Jacob G Sivak; Lyndon Jones
In vitro ultraviolet-induced damage in human corneal, lens, and retinal pigment epithelial cells.
Molecular vision 2011;17():237-46.
2010: Jacob G Sivak
The Charles F. Prentice award lecture 2009: Crystalline lens research and serendipity in science.
Optometry and vision science : official publication of the American Academy of Optometry 2010;87(9):622-30.
2009: Rasmus Jostrup; Wei Shen; Jeffrey T A Burrows; Jacob G Sivak; Brendan J McConkey; Thomas D Singer
Identification of myopia-related marker proteins in tilapia retinal, RPE, and choroidal tissue following induced form deprivation.
Current eye research 2009;34(11):966-75.
2009: Hyun-Yi Youn; B Ralph Chou; Anthony P Cullen; Jacob G Sivak
Effects of 400 nm, 420 nm, and 435.8 nm radiations on cultured human retinal pigment epithelial cells.
Journal of photochemistry and photobiology. B, Biology 2009;95(1):64-70.
2008: Brian P Danysh; Kirk J Czymmek; Pecos T Olurin; Jacob G Sivak; Melinda K Duncan
Contributions of mouse genetic background and age on anterior lens capsule thickness.
Anatomical record (Hoboken, N.J. : 2007) 2008;291(12):1619-27.
2008: Balamurali Vasudevan; Trefford L Simpson; Jacob G Sivak
Regional variation in the refractive-index of the bovine and human cornea.
Optometry and vision science : official publication of the American Academy of Optometry 2008;85(10):977-81.
2008: Jacob G Sivak
The role of the lens in refractive development of the eye: animal models of ametropia.
Experimental eye research 2008;87(1):3-8.
2008: Vladimir Bantseev; D J McCanna; Jean-Yves Driot; Jacob G Sivak
The effects of toxicological agents on the optics and mitochondria of the lens and the mitochondria of the corneal epithelium.
Seminars in cell & developmental biology 2008;19(2):150-9.
2008: Lesley Ho; Sara Di Carlo; Kelley L Moran; Vladimir Bantseev; Jacob G Sivak
Effect of age on ocular irritancy as measured with in vitro bovine lenses.
Toxicology in vitro : an international journal published in association with BIBRA 2008;22(2):450-6.
2007: Vladimir Bantseev; David J McCanna; Jean-Yves Driot; Keith W Ward; Jacob G Sivak
Biocompatibility of contact lens solutions using confocal laser scanning microscopy and the in vitro bovine cornea.
Eye & contact lens 2007;33(6 Pt 1):308-16.
2007: Wei Shen; Jacob G Sivak
Eyes of a lower vertebrate are susceptible to the visual environment.
Investigative ophthalmology & visual science 2007;48(10):4829-37.
2007: Hyun-Yi Youn; Vladimir Bantseev; Niels C Bols; Anthony P Cullen; Jacob G Sivak
In vitro assays for evaluating the ultraviolet B-induced damage in cultured human retinal pigment epithelial cells.
Journal of photochemistry and photobiology. B, Biology 2007;88(1):21-8.
2007: K Sivasegaran; L Ho; Kelley L Moran; Vladimir Bantseev; Jacob G Sivak
Dose-response of the cultured bovine lens to butyl, methyl and propyl parabens.
International journal of cosmetic science 2007;29(2):103-10.
2007: Alice Banh; Paula A Deschamps; Mathilakath M Vijayan; Jacob G Sivak; Judith A West-Mays
The role of Hsp70 and Hsp90 in TGF-beta-induced epithelial-to-mesenchymal transition in rat lens epithelial explants.
Molecular vision 2007;13():2248-62.
2007: Aphrodite Dracopoulos; D George Dixon; Lyndon Jones; Jacob G Sivak; Vladimir Bantseev
In vitro assessment of medical device toxicity: interactions of benzalkonium chloride with silicone-containing and p-hema-containing hydrogel contact lens materials.
Eye & contact lens 2007;33(1):26-37.
2006: Alice Banh; Paula A Deschamps; Jack Gauldie; Paul A Overbeek; Jacob G Sivak; Judith A West-Mays
Lens-specific expression of TGF-beta induces anterior subcapsular cataract formation in the absence of Smad3.
Investigative ophthalmology & visual science 2006;47(8):3450-60.
2006: Alice Banh; Vladimir Bantseev; Vivian Choh; Kelley L Moran; Jacob G Sivak
The lens of the eye as a focusing device and its response to stress.
Progress in retinal and eye research 2006;25(2):189-206.
2006: Dhruva J Dwivedi; Giuseppe Pino; Alice Banh; Zahra Nathu; Derek Howchin; Peter J Margetts; Jacob G Sivak; Judith A West-Mays
Matrix metalloproteinase inhibitors suppress transforming growth factor-beta-induced subcapsular cataract formation.
The American journal of pathology 2006;168(1):69-79.
2005: Vladimir Bantseev; Jacob G Sivak
Confocal laser scanning microscopy imaging of dynamic TMRE movement in the mitochondria of epithelial and superficial cortical fiber cells of bovine lenses.
Molecular vision 2005;11():518-23.
2005: Kevin L H van Doorn; Jacob G Sivak; Mathilakath M Vijayan
Optical quality changes of the ocular lens during induced parr-to-smolt metamorphosis in Rainbow Trout (Oncorhynchus mykiss). Ocular lens optical quality during induced salmonid metamorphosis.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 2005;191(7):649-57.
2005: Vladimir Bantseev; François Auclair; Réjean Dubuc; Jacob G Sivak
Optical quality of the ocular lens of the sea lamprey (Petromyzon marinus) during the mature and transformer periods of life.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 2005;191(6):505-9.
2005: Wei Shen; Mathilakath Vijayan; Jacob G Sivak
Inducing form-deprivation myopia in fish.
Investigative ophthalmology & visual science 2005;46(5):1797-803.
2005: Vivian Choh; Jacob G Sivak
Lenticular accommodation in relation to ametropia: the chick model.
Journal of vision 2005;5(3):165-76.
2004: Hyun-Yi Youn; Kelley L Moran; Olanrewaju M Oriowo; Niels C Bols; Jacob G Sivak
Surfactant and UV-B-induced damage of the cultured bovine lens.
Toxicology in vitro : an international journal published in association with BIBRA 2004;18(6):841-52.
2004: Vladimir Bantseev; Olanrewaju M Oriowo; Frank J Giblin; Victor R Leverenz; John R Trevithick; Jacob G Sivak
Effect of hyperbaric oxygen on guinea pig lens optical quality and on the refractive state of the eye.
Experimental eye research 2004;78(5):925-31.
2004: Alice Banh; Jacob G Sivak
Laser scanning analysis of cold cataract in young and old bovine lenses.
Molecular vision 2004;10():144-7.
2004: Jacob G Sivak
Through the lens clearly: phylogeny and development: the Proctor lecture.
Investigative ophthalmology & visual science 2004;45(3):740-7; 739.
2003: Andrew T E Hartwick; Jacob G Sivak
Epithelial activity of hexokinase and glucose-6-phosphate dehydrogenase in cultured bovine lenses recovering from pharmaceutical-induced optical damage.
Molecular vision 2003;9():594-600.
2003: W Wong; Jacob G Sivak; Kelley L Moran
Optical response of the cultured bovine lens; testing opaque or partially transparent semi-solid/solid common consumer hygiene products.
Toxicology in vitro : an international journal published in association with BIBRA 2003;17(5-6):785-90.
2003: Vladimir Bantseev; Anthony P Cullen; John R Trevithick; Jacob G Sivak
Optical function and mitochondrial metabolic properties in damage and recovery of bovine lens after in vitro carbonyl cyanide m-chlorophenylhydrazone treatment.
Mitochondrion 2003;3(1):1-11.
2003: Alice Banh; Mathilakath M Vijayan; Jacob G Sivak
Hsp70 in bovine lenses during temperature stress.
Molecular vision 2003;9():323-8.
2003: Vladimir Bantseev; David McCanna; Alice Banh; Winnie W Wong; Kelley L Moran; D George Dixon; John R Trevithick; Jacob G Sivak
Mechanisms of ocular toxicity using the in vitro bovine lens and sodium dodecyl sulfate as a chemical model.
Toxicological sciences : an official journal of the Society of Toxicology 2003;73(1):98-107.
2003: Sharon T Wong; Alexander K Ball; Jacob G Sivak
Model of retinal surface area and neuron distribution in the avian eye.
Journal of neuroscience methods 2003;123(1):1-9.
2002: Sophia Zaidi; Michelle Senchyna; Jacob G Sivak
Quantification of chick lens alphaA- and delta-crystallins in experimentally induced ametropia.
Molecular vision 2002;8():472-6.
2002: Jer R Kuszak; Jacob G Sivak; K L Moran; Sally A Scheib; William Howard Garner; Tai-Lee Ke; Mark R Hellberg; Gustav Graff
Suppression of post-vitrectomy lens changes in the rabbit by novel benzopyranyl esters and amides.
Experimental eye research 2002;75(4):459-73.
2002: Olanrewaju M Oriowo; Anthony P Cullen; Kristin Schirmer; B Ralph Chou; Niels C Bols; Jacob G Sivak
Evaluation of a porcine lens and fluorescence assay approach for in vitro ocular toxicological investigations.
Alternatives to laboratory animals : ATLA 2002;30(5):505-13.
2002: Olanrewaju M Oriowo; Anthony P Cullen; Jacob G Sivak
Impairment of eye lens cell physiology and optics by broadband ultraviolet A-ultraviolet B radiation.
Photochemistry and photobiology 2002;76(3):361-7.
2002: Vivian Choh; Jacob G Sivak; Elizabeth L Irving; Winnie Wong
Ultrasound biomicroscopy of the anterior segment of the enucleated chicken eye during accommodation.
Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) 2002;22(5):401-8.
2002: Vivian Choh; Jacob G Sivak; Stephen D Meriney
A physiological model to measure effects of age on lenticular accommodation and spherical aberration in chickens.
Investigative ophthalmology & visual science 2002;43(1):92-8.
2001: Olanrewaju M Oriowo; Anthony P Cullen; B Ralph Chou; Jacob G Sivak
Action spectrum and recovery for in vitro UV-induced cataract using whole lenses.
Investigative ophthalmology & visual science 2001;42(11):2596-602.
2000: Rhonda C Bell; John C Carlson; K C Storr; KL Herbert; Jacob G Sivak
High-fructose feeding of streptozotocin-diabetic rats is associated with increased cataract formation and increased oxidative stress in the kidney.
The British journal of nutrition 2000;84(4):575-82.
2000: S Priolo; Jacob G Sivak; Jer R Kuszak; Elizabeth L Irving
Effects of experimentally induced ametropia on the morphology and optical quality of the avian crystalline lens.
Investigative ophthalmology & visual science 2000;41(11):3516-22.
2000: Jer R Kuszak; Jacob G Sivak; K L Herbert; Sally A Scheib; William Howard Garner; Gustav Graff
The relationship between rabbit lens optical quality and sutural anatomy after vitrectomy.
Experimental eye research 2000;71(3):267-81.
2000: M T Pardue; Jacob G Sivak
Age-related changes in human ciliary muscle.
Optometry and vision science : official publication of the American Academy of Optometry 2000;77(4):204-10.
2000: Jeffrey Whyte; KL Herbert; Niel Karrow; D George Dixon; Jacob G Sivak; Niels C Bols
Effect of maintaining rainbow trout in creosote microcosms on lens optical properties and liver 7-ethoxyresorufin-O-deethylase (EROD) activity.
Archives of environmental contamination and toxicology 2000;38(3):350-6.
2000: N L Laycock; Kristin Schirmer; Niels C Bols; Jacob G Sivak
Optical properties of rainbow trout lenses after in vitro exposure to polycyclic aromatic hydrocarbons in the presence or absence of ultraviolet radiation.
Experimental eye research 2000;70(2):205-14.
1999: S Priolo; Jacob G Sivak; Jer R Kuszak
Effect of age on the morphology and optical quality of the avian crystalline lens.
Experimental eye research 1999;69(6):629-40.
1999: Vladimir Bantseev; KL Herbert; John R Trevithick; Jacob G Sivak
Mitochondria of rat lenses: distribution near and at the sutures.
Current eye research 1999;19(6):506-16.
1999: KL Herbert; Jacob G Sivak; Rhonda C Bell
Effect of diabetes and fructose/non-fructose diet on the optical quality (cataracts) of the rat lens.
Current eye research 1999;19(4):305-12.
1999: Jer R Kuszak; Kristin J al-Ghoul; Layne A Novak; K L Peterson; K L Herbert; Jacob G Sivak
The internalization of posterior subcapsular cataracts (PSCs) in Royal College of Surgeons (RCS) rats. II. The inter-relationship of optical quality and structure as a function of age.
Molecular vision 1999;5():7.
1999: T A Curry; Jacob G Sivak; Murchison G Callender; Elizabeth L Irving
Afocal magnification does not influence chick eye development.
Optometry and vision science : official publication of the American Academy of Optometry 1999;76(5):316-9.
1997: Keith T Wilson; Jacob G Sivak; Murchison G Callender
Induced refractive anomalies affect chick orbital bone structure.
Experimental eye research 1997;64(5):675-82.
1997: M T Pardue; Jacob G Sivak
The functional anatomy of the ciliary muscle in four avian species.
Brain, behavior and evolution 1997;49(6):295-311.
1996: S S Guo; Jacob G Sivak; M G Callender; K L Herbert
Effects of continuous light on experimental refractive errors in chicks.
Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) 1996;16(6):486-90.
1996: M E Andison; Jacob G Sivak
The naturally occurring accommodative response of the oscar, Astronotus ocellatus, to visual stimuli.
Vision research 1996;36(19):3021-7.
1996: Elizabeth L Irving; Jacob G Sivak; T A Curry; M G Callender
Chick eye optics: zero to fourteen days.
Journal of comparative physiology. A, Sensory, neural, and behavioral physiology 1996;179(2):185-94.
1995: Jacob G Sivak; K L Herbert; Desmond Fonn
In vitro ocular irritancy measure of four contact lens solutions: damage and recovery.
The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc 1995;21(3):169-74.
1995: M T Pardue; C A Luer; M G Callender; B Ralph Chou; Jacob G Sivak
The absence of a photopic influence on the refractive development of the embryonic eye of the clearnose skate (Raja eglanteria).
Vision research 1995;35(12):1675-8.
1995: S S Guo; Jacob G Sivak; M G Callender; B Diehl-Jones
Retinal dopamine and lens-induced refractive errors in chicks.
Current eye research 1995;14(5):385-9.
1995: Elizabeth L Irving; M G Callender; Jacob G Sivak
Inducing ametropias in hatchling chicks by defocus--aperture effects and cylindrical lenses.
Vision research 1995;35(9):1165-74.
1995: J A West; Jacob G Sivak; Michael J Doughty
Microscopical evaluation of the crystalline lens of the squid (Loligo opalescens) during embryonic development.
Experimental eye research 1995;60(1):19-35.
1994: Jer R Kuszak; K L Peterson; Jacob G Sivak; K L Herbert
The interrelationship of lens anatomy and optical quality. II. Primate lenses.
Experimental eye research 1994;59(5):521-35.
1994: Jacob G Sivak; K L Herbert; K L Peterson; Jer R Kuszak
The interrelationship of lens anatomy and optical quality. I. Non-primate lenses.
Experimental eye research 1994;59(5):505-20.
1994: Anthony P Cullen; C A Monteith-McMaster; Jacob G Sivak
Lenticular changes in rainbow trout following chronic exposure to UV radiation.
Current eye research 1994;13(10):731-7.
1994: Jacob G Sivak; J A West; Melanie C W Campbell
Growth and optical development of the ocular lens of the squid (Sepioteuthis lessoniana).
Vision research 1994;34(17):2177-87.
1994: D D Stuart; Anthony P Cullen; Jacob G Sivak; Michael J Doughty
Optical effects of UV-A and UV-B radiation on the cultured bovine lens.
Current eye research 1994;13(5):371-6.
1994: J A West; Jacob G Sivak; J Pasternak; J Piatigorsky
Immunolocalization of S-crystallins in the developing squid (Loligo opalescens) lens.
Developmental dynamics : an official publication of the American Association of Anatomists 1994;199(2):85-92.
1993: A Dovrat; J Horwitz; Jacob G Sivak; O Weinreb; J Scharf; M Silbermann
DL-propranolol inhibits lens hexokinase activity and affects lens optics.
Experimental eye research 1993;57(6):747-51.
1992: R L Pickett-Seltner; Michael J Doughty; J J Pasternak; Jacob G Sivak
Proteins of the vitreous humor during experimentally induced myopia.
Investigative ophthalmology & visual science 1992;33(12):3424-9.
1992: Elizabeth L Irving; Jacob G Sivak; M G Callender
Refractive plasticity of the developing chick eye.
Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) 1992;12(4):448-56.
1992: M E Andison; Jacob G Sivak; D M Bird
The refractive development of the eye of the American kestrel (Falco sparverius): a new avian model.
Journal of comparative physiology. A, Sensory, neural, and behavioral physiology 1992;170(5):565-74.
1992: J A Weerheim; Jacob G Sivak
Scanning laser measure of optical quality of the cultured crystalline lens.
Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) 1992;12(1):72-9.
1991: J A West; Jacob G Sivak; Michael J Doughty
Role of accommodation in experimental myopia in chicks.
Optometry and vision science : official publication of the American Academy of Optometry 1991;68(11):847-52.
1991: Jer R Kuszak; Jacob G Sivak; J A Weerheim
Lens optical quality is a direct function of lens sutural architecture.
Investigative ophthalmology & visual science 1991;32(7):2119-29.
1991: Elizabeth L Irving; M G Callender; Jacob G Sivak
Inducing myopia, hyperopia, and astigmatism in chicks.
Optometry and vision science : official publication of the American Academy of Optometry 1991;68(5):364-8.
1991: D D Stuart; Jacob G Sivak; Anthony P Cullen; J A Weerheim; C A Monteith
UV-B radiation and the optical properties of cultured bovine lenses.
Current eye research 1991;10(2):177-84.
1991: Jacob G Sivak; C A Luer
Optical development of the ocular lens of an elasmobranch, Raja eglanteria [corrected].
Vision research 1991;31(3):373-82.
1990: Jacob G Sivak; M Yoshimura; J Weerheim; A Dovrat
Effect of hydrogen peroxide, DL-propranolol, and prednisone on bovine lens optical function in culture.
Investigative ophthalmology & visual science 1990;31(5):954-63.
1990: Jacob G Sivak; D L Barrie; M G Callender; Michael J Doughty; R L Seltner; J A West
Optical causes of experimental myopia.
Ciba Foundation symposium 1990;155():160-72; discussion 172-7.
1989: Jacob G Sivak; D L Barrie; J A Weerheim
Bilateral experimental myopia in chicks.
Optometry and vision science : official publication of the American Academy of Optometry 1989;66(12):854-8.
1989: Jacob G Sivak; H C Howland; J West; J Weerheim
The eye of the hooded seal, Cystophora cristata, in air and water.
Journal of comparative physiology. A, Sensory, neural, and behavioral physiology 1989;165(6):771-7.
1989: Jacob G Sivak; L A Ryall; J Weerheim; Melanie C W Campbell
Optical constancy of the chick lens during pre- and post-hatching ocular development.
Investigative ophthalmology & visual science 1989;30(5):967-74.
1989: R L Seltner; J A Weerheim; Jacob G Sivak
Role of the lens and vitreous humor in the refractive properties of the eyes of three strains of goldfish.
Vision research 1989;29(6):681-5.
1988: R L Pickett-Seltner; Jacob G Sivak; J J Pasternak
Experimentally induced myopia in chicks: morphometric and biochemical analysis during the first 14 days after hatching.
Vision research 1988;28(2):323-8.
1987: R L Seltner; Jacob G Sivak
A role for the vitreous humor in experimentally-induced myopia.
American journal of optometry and physiological optics 1987;64(12):953-7.
1987: Jacob G Sivak; A Dovrat
Embryonic lens of the human eye as an optical structure.
American journal of optometry and physiological optics 1987;64(8):599-603.
1987: R L Pickett-Seltner; J Weerheim; Jacob G Sivak; J Pasternak
Experimentally induced myopia does not affect post-hatching development of the chick lens.
Vision research 1987;27(10):1779-82.
1986: Jacob G Sivak; D Gershon; A Dovrat; J Weerheim
Computer assisted scanning laser monitor of optical quality of the excised crystalline lens.
Vision research 1986;26(11):1873-9.
1986: Jacob G Sivak; T E Hildebrand; C G Lebert; L M Myshak; L A Ryall
Ocular accommodation in chickens: corneal vs lenticular accommodation and effect of age.
Vision research 1986;26(11):1865-72.
1983: Jacob G Sivak; A Dovrat
Aging and the optical quality of the rat crystalline lens.
Investigative ophthalmology & visual science 1983;24(9):1162-6.
1983: Jacob G Sivak; M Gur; A Dovrat
Spherical aberration of the lens of the ground squirrel (Spermophilis tridecemlineatus).
Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) 1983;3(3):261-5.