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William Sivitz

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Mei-Ling A Joiner; Olha M Koval; Jingdong Li; Elizabeth D Luczak; Peter J Mohler; Steven A Moore; Thomas D Scholz; William I Sivitz; Long-Sheng Song; Stefan Strack; Jinying Yang; Biyi Chen; Brian D Fink; Zhan Gao; Duane D Hall; B Julie He; Chantal Allamargot; Mark E Anderson
CaMKII determines mitochondrial stress responses in heart.
Brian D Fink; Judy A Herlein; Robert J Kerns; Amanda M Fenner; Mark A Yorek; William I Sivitz
Bioenergetic effects of mitochondrial-targeted coenzyme Q analogs in endothelial cells.
Shanming Hu; Brandon M Menke; William I Sivitz; Arthur A Spector; Jianrong Yao; Alexander A Howe; Andrew W Norris
Peroxisome proliferator-activated receptor γ decouples fatty acid uptake from lipid inhibition of insulin signaling in skeletal muscle.

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2012: Mei-Ling A Joiner; Olha M Koval; Jingdong Li; Elizabeth D Luczak; Peter J Mohler; Steven A Moore; Thomas D Scholz; William I Sivitz; Long-Sheng Song; Stefan Strack; Jinying Yang; Biyi Chen; Brian D Fink; Zhan Gao; Duane D Hall; B Julie He; Chantal Allamargot; Mark E Anderson
CaMKII determines mitochondrial stress responses in heart.
Nature 2012;491(7423):269-73.
2012: Brian D Fink; Judy A Herlein; Robert J Kerns; Amanda M Fenner; Mark A Yorek; William I Sivitz
Bioenergetic effects of mitochondrial-targeted coenzyme Q analogs in endothelial cells.
The Journal of pharmacology and experimental therapeutics 2012;342(3):709-19.
2012: Shanming Hu; Brandon M Menke; William I Sivitz; Arthur A Spector; Jianrong Yao; Alexander A Howe; Andrew W Norris
Peroxisome proliferator-activated receptor γ decouples fatty acid uptake from lipid inhibition of insulin signaling in skeletal muscle.
Molecular endocrinology (Baltimore, Md.) 2012;26(6):977-88.
2012: Brian D Fink; Judy A Herlein; Yunxia Q O'Malley; William I Sivitz
Endothelial cell and platelet bioenergetics: effect of glucose and nutrient composition.
PloS one 2012;7(6):e39430.
2011: Judy A Herlein; Brian D Fink; Dorlyne M Henry; Lynn M Teesch; Mark A Yorek; William I Sivitz
Mitochondrial superoxide and coenzyme Q in insulin-deficient rats: increased electron leak.
American journal of physiology. Regulatory, integrative and comparative physiology 2011;301(6):R1616-24.
2011: Rinku Mehra; Eva Tsalikian; Catherine A Chenard; M Bridget Zimmerman; William I Sivitz
Feeding frequency and appetite in lean and obese prepubertal children.
Obesity (Silver Spring, Md.) 2011;19(3):560-7.
2010: William I Sivitz; Mark A Yorek
Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities.
Antioxidants & redox signaling 2010;12(4):537-77.
2010: Judy A Herlein; Brian D Fink; William I Sivitz
Superoxide production by mitochondria of insulin-sensitive tissues: mechanistic differences and effect of early diabetes.
Metabolism: clinical and experimental 2010;59(2):247-57.
2010: Denise E Bonds; Michael E Miller; Richard M Bergenstal; John B Buse; Robert P Byington; Jeff A Cutler; R James Dudl; Faramarz Ismail-Beigi; Angela R Kimel; Byron Hoogwerf; Karen R Horowitz; Peter J Savage; Elizabeth R Seaquist; Debra L Simmons; William I Sivitz; Joann M Speril-Hillen; Mary Ellen Sweeney
The association between symptomatic, severe hypoglycaemia and mortality in type 2 diabetes: retrospective epidemiological analysis of the ACCORD study.
BMJ (Clinical research ed.) 2010;340():b4909.
2009: Rinku Mehra; Ramesh Raman; Margaret L Bayless; William I Sivitz
Antecedent caloric intake and glucose excursion following a subsequent meal in Type 1 diabetes.
Journal of diabetes 2009;1(4):273-7.
2009: Chadi A Calarge; Vicki E Ringold; Bridget Zimmerman; Laura Acion; William I Sivitz; Janet A Schlechte
Leptin gene -2548G/A variants predict risperidone-associated weight gain in children and adolescents.
Psychiatric genetics 2009;19(6):320-7.
2009: Brian D Fink; Yunxia O'Malley; Brian L Dake; Nicolette C Ross; Thomas E Prisinzano; William I Sivitz
Mitochondrial targeted coenzyme Q, superoxide, and fuel selectivity in endothelial cells.
PloS one 2009;4(1):e4250.
2009: Judy A Herlein; Brian D Fink; Yunxia O'Malley; William I Sivitz
Superoxide and respiratory coupling in mitochondria of insulin-deficient diabetic rats.
Endocrinology 2009;150(1):46-55.
2008: Andrew W Norris; Michael F Hirshman; Jianrong Yao; Niels Jessen; Nicolas Musi; Lihong Chen; William I Sivitz; Laurie J Goodyear; C Ronald Kahn
Endogenous peroxisome proliferator-activated receptor-gamma augments fatty acid uptake in oxidative muscle.
Endocrinology 2008;149(11):5374-83.
2007: Brian D Fink; Judy A Herlein; Katrine Almind; Saverio Cinti; C Ronald Kahn; William I Sivitz
Mitochondrial proton leak in obesity-resistant and obesity-prone mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;293(5):R1773-80.
2007: William I Sivitz; Sheila M Wayson; Margaret L Bayless; Christine A Sinkey; William G Haynes
Obesity impairs vascular relaxation in human subjects: hyperglycemia exaggerates adrenergic vasoconstriction arterial dysfunction in obesity and diabetes.
Journal of diabetes and its complications 2007;21(3):149-57.
2007: Katrine Almind; Monia Manieri; William I Sivitz; Saverio Cinti; C Ronald Kahn
Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(7):2366-71.
2006: Yunxia Q O'Malley; Brian D Fink; Nicolette C Ross; Thomas E Prisinzano; William I Sivitz
Reactive oxygen and targeted antioxidant administration in endothelial cell mitochondria.
The Journal of biological chemistry 2006;281(52):39766-75.
2006: Judy A Herlein; Donald A Morgan; Bradley G Phillips; William G Haynes; William I Sivitz
Antecedent hypoglycemia, catecholamine depletion, and subsequent sympathetic neural responses.
Endocrinology 2006;147(6):2781-8.
2005: Saul Genuth; Wanjie Sun; Patricia Cleary; David R Sell; William Dahms; John Malone; William I Sivitz; Vincent M Monnier
Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complications participants with type 1 diabetes.
Diabetes 2005;54(11):3103-11.
2005: Twyla B Bartel; Malik E Juweid; Thomas M O'Dorisio; William I Sivitz; Patricia A Kirby
Scintigraphic detection of benign struma ovarii in a hyperthyroid patient.
The Journal of clinical endocrinology and metabolism 2005;90(6):3771-2.
2005: Brian D Fink; Krzysztof J Reszka; Judy A Herlein; Mary M Mathahs; William I Sivitz
Respiratory uncoupling by UCP1 and UCP2 and superoxide generation in endothelial cell mitochondria.
American journal of physiology. Endocrinology and metabolism 2005;288(1):E71-9.
2004: Jamie W Joseph; Vasilij Koshkin; Monique C Saleh; William I Sivitz; Chen-Yu zhang; Bradford B Lowell; Catherine B Chan; Michael B Wheeler
Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression.
The Journal of biological chemistry 2004;279(49):51049-56.
2004: Darcy M Putz; Whitney S Goldner; Robert S Bar; William G Haynes; William I Sivitz
Adiponectin and C-reactive protein in obesity, type 2 diabetes, and monodrug therapy.
Metabolism: clinical and experimental 2004;53(11):1454-61.
2004: Whitney S Goldner; Vicki L Kraus; William I Sivitz; Stephen K Hunter; Joseph S Dillon
Cyclic changes in glycemia assessed by continuous glucose monitoring system during multiple complete menstrual cycles in women with type 1 diabetes.
Diabetes technology & therapeutics 2004;6(4):473-80.
2004: William I Sivitz
Understanding insulin resistance. What are the clinical implications?
Postgraduate medicine 2004;116(1):41-8.
2003: Judy A Herlein; Brian D Fink; Donald A Morgan; Bradley G Phillips; William G Haynes; William I Sivitz
Leptin administration to normal rats does not alter catecholamine responsiveness to insulin-induced hypoglycemia.
Metabolism: clinical and experimental 2003;52(11):1484-90.
2003: William I Sivitz; Sheila M Wayson; Margaret L Bayless; Linda F Larson; Christine A Sinkey; Robert S Bar; William G Haynes
Leptin and body fat in type 2 diabetes and monodrug therapy.
The Journal of clinical endocrinology and metabolism 2003;88(4):1543-53.
2002: Martin Hausberg; Donald A Morgan; Mark A Chapleau; William I Sivitz; Allyn L Mark; William G Haynes
Differential modulation of leptin-induced sympathoexcitation by baroreflex activation.
Journal of hypertension 2002;20(8):1633-41.
2002: Martin Hausberg; Donald A Morgan; Jennifer L Mitchell; William I Sivitz; Allyn L Mark; William G Haynes
Leptin potentiates thermogenic sympathetic responses to hypothermia: a receptor-mediated effect.
Diabetes 2002;51(8):2434-40.
2002: Allyn L Mark; William I Sivitz
Uncoupling metabolism and coupling leptin to cardiovascular disease.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(6):881-3.
2002: Brian D Fink; Young-Sun Hong; Mary M Mathahs; Thomas D Scholz; Joseph S Dillon; William I Sivitz
UCP2-dependent proton leak in isolated mammalian mitochondria.
The Journal of biological chemistry 2002;277(6):3918-25.
2002: Marcelo L G Correia; Donald A Morgan; William I Sivitz; Allyn L Mark; William G Haynes
Hemodynamic consequences of neuropeptide Y-induced obesity.
American journal of hypertension 2002;15(2 Pt 1):137-42.
2002: Marcelo L G Correia; William G Haynes; Kamal Rahmouni; Donald A Morgan; William I Sivitz; Allyn L Mark
The concept of selective leptin resistance: evidence from agouti yellow obese mice.
Diabetes 2002;51(2):439-42.
2001: Jennifer L Mitchell; Donald A Morgan; Marcelo L G Correia; Allyn L Mark; William I Sivitz; William G Haynes
Does leptin stimulate nitric oxide to oppose the effects of sympathetic activation?
Hypertension 2001;38(5):1081-6.
2001: Marcelo L G Correia; Donald A Morgan; Jennifer L Mitchell; William I Sivitz; Allyn L Mark; William G Haynes
Role of corticotrophin-releasing factor in effects of leptin on sympathetic nerve activity and arterial pressure.
Hypertension 2001;38(3):384-8.
2001: A Jalali; Donald A Morgan; William I Sivitz; Marcelo L G Correia; Allyn L Mark; William G Haynes
Does leptin cause functional peripheral sympatholysis?
American journal of hypertension 2001;14(7 Pt 1):615-8.
2001: Krzysztof Narkiewicz; Masahiko Kato; Bradley G Phillips; CA Pesek; Ian Choe; Mikolaj Winnicki; Paolo Palatini; William I Sivitz; Virend K Somers
Leptin interacts with heart rate but not sympathetic nerve traffic in healthy male subjects.
Journal of hypertension 2001;19(6):1089-94.
2001: William I Sivitz; Judy A Herlein; Donald A Morgan; Brian D Fink; Bradley G Phillips; William G Haynes
Effect of acute and antecedent hypoglycemia on sympathetic neural activity and catecholamine responsiveness in normal rats.
Diabetes 2001;50(5):1119-25.
2001: William I Sivitz
Lipotoxicity and glucotoxicity in type 2 diabetes. Effects on development and progression.
Postgraduate medicine 2001;109(4):55-9, 63-4.
2001: Marcelo L G Correia; Donald A Morgan; William I Sivitz; Allyn L Mark; William G Haynes
Leptin acts in the central nervous system to produce dose-dependent changes in arterial pressure.
Hypertension 2001;37(3):936-42.
2001: Y Hong; Brian D Fink; Joseph S Dillon; William I Sivitz
Effects of adenoviral overexpression of uncoupling protein-2 and -3 on mitochondrial respiration in insulinoma cells.
Endocrinology 2001;142(1):249-56.
2000: Robert P Hoffman; P Vicini; William I Sivitz; C Cobelli
Pubertal adolescent male-female differences in insulin sensitivity and glucose effectiveness determined by the one compartment minimal model.
Pediatric research 2000;48(3):384-8.
1999: William I Sivitz; Brian D Fink; Donald A Morgan; J M Fox; Patricia A Donohoue; William G Haynes
Sympathetic inhibition, leptin, and uncoupling protein subtype expression in normal fasting rats.
The American journal of physiology 1999;277(4 Pt 1):E668-77.
1999: William I Sivitz; Brian D Fink; Patricia A Donohoue
Fasting and leptin modulate adipose and muscle uncoupling protein: divergent effects between messenger ribonucleic acid and protein expression.
Endocrinology 1999;140(4):1511-9.
1999: Krzysztof Narkiewicz; Radoslaw Szczech; Mikolaj Winnicki; Marzena Chrostowska; Ryszard Pawlowski; Wieslawa Lysiak-Szydlowska; Ian Choe; Masahiko Kato; William I Sivitz; Barbara Krupa-Wojciechowska; Virend K Somers
Heritability of plasma leptin levels: a twin study.
Journal of hypertension 1999;17(1):27-31.
1999: William G Haynes; Donald A Morgan; A Djalali; William I Sivitz; Allyn L Mark
Interactions between the melanocortin system and leptin in control of sympathetic nerve traffic.
Hypertension 1999;33(1 Pt 2):542-7.
1998: William I Sivitz; S Walsh; D Morgan; Patricia A Donohoue; William G Haynes; Rudolph L Leibel
Plasma leptin in diabetic and insulin-treated diabetic and normal rats.
Metabolism: clinical and experimental 1998;47(5):584-91.
1998: William G Haynes; Donald A Morgan; Susan A Walsh; William I Sivitz; Allyn L Mark
Cardiovascular consequences of obesity: role of leptin.
Clinical and experimental pharmacology & physiology 1998;25(1):65-9.
1997: William G Haynes; William I Sivitz; Donald A Morgan; Susan A Walsh; Allyn L Mark
Sympathetic and cardiorenal actions of leptin.
Hypertension 1997;30(3 Pt 2):619-23.
1997: A H Talal; Joseph A Murray; J Adam Goeken; William I Sivitz
Celiac disease in an adult population with insulin-dependent diabetes mellitus: use of endomysial antibody testing.
The American journal of gastroenterology 1997;92(8):1280-4.
1997: William I Sivitz; Susan A Walsh; Donald A Morgan; M J Thomas; William G Haynes
Effects of leptin on insulin sensitivity in normal rats.
Endocrinology 1997;138(8):3395-401.
1997: William G Haynes; Donald A Morgan; Susan A Walsh; Allyn L Mark; William I Sivitz
Receptor-mediated regional sympathetic nerve activation by leptin.
The Journal of clinical investigation 1997;100(2):270-8.
1996: William I Sivitz; H L Bailey; Patricia A Donohoue
Rat adipose ob mRNA levels in states of altered circulating glucose and insulin.
Biochemical and biophysical research communications 1996;220(3):520-5.
1995: William I Sivitz; A M Pasley
Glucocorticoid effects on glucose transport and transporter gene expression in L6 muscle cells.
Biochemical and biophysical research communications 1995;206(1):51-6.
1992: William I Sivitz; S L DeSautel; E C Lee; Jeffrey Pessin
Time-dependent regulation of rat adipose tissue glucose transporter (GLUT4) mRNA and protein by insulin in streptozocin-diabetic and normal rats.
Metabolism: clinical and experimental 1992;41(11):1267-72.
1991: G I Bell; H Fukumoto; Charles F Burant; S Seino; William I Sivitz; Jeffrey Pessin
Facilitative glucose transport proteins: structure and regulation of expression in adipose tissue.
International journal of obesity 1991;15 Suppl 2():127-32.
1991: William I Sivitz; E C Lee
Assessment of glucose transporter gene expression using the polymerase chain reaction.
Endocrinology 1991;128(5):2387-94.
1991: Jeffrey Pessin; J M Richardson; William I Sivitz
Regulation of the glucose transporter in animal models of diabetes.
Advances in experimental medicine and biology 1991;293():249-62.
1991: Charles F Burant; William I Sivitz; H Fukumoto; T Kayano; S Nagamatsu; S Seino; Jeffrey Pessin; Graeme I Bell
Mammalian glucose transporters: structure and molecular regulation.
Recent progress in hormone research 1991;47():349-87; discussion 387-8.
1990: William I Sivitz; S L DeSautel; T Kayano; Graeme I Bell; Jeffrey Pessin
Regulation of glucose transporter messenger RNA levels in rat adipose tissue by insulin.
Molecular endocrinology (Baltimore, Md.) 1990;4(4):583-8.
1989: William I Sivitz; S L DeSautel; T Kayano; Graeme I Bell; Jeffrey Pessin
Regulation of glucose transporter messenger RNA in insulin-deficient states.
Nature 1989;340(6228):72-4.
1989: William I Sivitz; S DeSautel; P S Walker; Jeffrey Pessin
Regulation of the glucose transporter in developing rat brain.
Endocrinology 1989;124(4):1875-80.