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Niels Skakkebaek

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Disorders

Anatomy

Testis
Semen

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Denmark

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Publications

TOP 3
Boas Malene; Hegedüs Laszlo; Feldt-Rasmussen Ulla; Skakkebaek Niels E; Hilsted Linda; Main Katharina M
Association of thyroid gland volume, serum insulin-like growth factor-I, and anthropometric variables in euthyroid prepubertal children.
Aksglaede L; Jørgensen N; Skakkebaek N E; Juul A
Low semen volume in 47 adolescents and adults with 47,XXY Klinefelter or 46,XX male syndrome.
Wohlfahrt-Veje Christine; Boisen Kirsten A; Boas Malene; Damgaard Ida N; Kai Claudia M; Schmidt Ida M; Chellakooty Marla; Suomi Anne-Maarit; Toppari Jorma; Skakkebaek Niels E; Main Katharina M
Acquired cryptorchidism is frequent in infancy and childhood.

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All Publications

2009: Boas Malene; Hegedüs Laszlo; Feldt-Rasmussen Ulla; Skakkebaek Niels E; Hilsted Linda; Main Katharina M
Association of thyroid gland volume, serum insulin-like growth factor-I, and anthropometric variables in euthyroid prepubertal children.
The Journal of clinical endocrinology and metabolism 2009;94(10):4031-5.
2009: Aksglaede L; Jørgensen N; Skakkebaek N E; Juul A
Low semen volume in 47 adolescents and adults with 47,XXY Klinefelter or 46,XX male syndrome.
International journal of andrology 2009;32(4):376-84.
2009: Wohlfahrt-Veje Christine; Boisen Kirsten A; Boas Malene; Damgaard Ida N; Kai Claudia M; Schmidt Ida M; Chellakooty Marla; Suomi Anne-Maarit; Toppari Jorma; Skakkebaek Niels E; Main Katharina M
Acquired cryptorchidism is frequent in infancy and childhood.
International journal of andrology 2009;32(4):423-8.
2009: Joensen Ulla Nordström; Bossi Rossana; Leffers Henrik; Jensen Allan Astrup; Skakkebaek Niels E; Jørgensen Niels
Do perfluoroalkyl compounds impair human semen quality?
Environmental health perspectives 2009;117(6):923-7.
2009: Sonne Si Brask; Almstrup Kristian; Dalgaard Marlene; Juncker Agnieszka Sierakowska; Edsgard Daniel; Ruban Ludmila; Harrison Neil J; Schwager Christian; Abdollahi Amir; Huber Peter E; Brunak Søren; Gjerdrum Lise Mette; Moore Harry D; Andrews Peter W; Skakkebaek Niels E; Rajpert-De Meyts Ewa; Leffers Henrik
Analysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyte.
Cancer research 2009;69(12):5241-50.
2009: Aksglaede Lise; Sørensen Kaspar; Petersen Jørgen H; Skakkebaek Niels E; Juul Anders
Recent decline in age at breast development: the Copenhagen Puberty Study.
Pediatrics 2009;123(5):e932-9.
2009: Joensen Ulla Nordström; Skakkebaek Niels E; Jørgensen Niels
Is there a problem with male reproduction?
Nature clinical practice. Endocrinology & metabolism 2009;5(3):144-5.
2009: Main Katharina M; Skakkebaek Niels E; Toppari Jorma
Re: The true incidence of cryptorchidism in Denmark: D. Cortes, E. M. Kjellberg, M. Breddam and J. Thorup, J Urol 2008; 179: 314-318.
The Journal of urology 2009;181(2):922-4.
2009: Teilmann Grete; Petersen Jørgen H; Gormsen Magdalena; Damgaard Karen; Skakkebaek Niels E; Jensen Tina Kold
Early puberty in internationally adopted girls: hormonal and clinical markers of puberty in 276 girls examined biannually over two years.
Hormone research 2009;72(4):236-46.
2009: Main K M; Skakkebaek N E; Toppari J
Cryptorchidism as part of the testicular dysgenesis syndrome: the environmental connection.
Endocrine development 2009;14():167-73.
2008: Blomberg Jensen M; Leffers H; Petersen J H; Daugaard G; Skakkebaek N E; Rajpert-De Meyts E
Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase gamma gene (POLG) with testicular germ-cell cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19(11):1910-4.
2008: Bay Katrine; Cohen Arieh S; Jørgensen Finn Stener; Jørgensen Connie; Lind Anne Marie; Skakkebaek Niels E; Andersson Anna-Maria
Insulin-like factor 3 levels in second-trimester amniotic fluid.
The Journal of clinical endocrinology and metabolism 2008;93(10):4048-51.
2008: Mau Kai C; Juul A; McElreavey K; Ottesen A M; Garn I D; Main K M; Loft A; Jørgensen N; Skakkebaek N E; Andersen A Nyboe; Rajpert-De Meyts E
Sons conceived by assisted reproduction techniques inherit deletions in the azoospermia factor (AZF) region of the Y chromosome and the DAZ gene copy number.
Human reproduction (Oxford, England) 2008;23(7):1669-78.
2008: Kristensen David Møbjerg; Sonne Si Brask; Ottesen Anne Marie; Perrett Rebecca M; Nielsen John E; Almstrup Kristian; Skakkebaek Niels E; Leffers Henrik; Meyts Ewa Rajpert-De
Origin of pluripotent germ cell tumours: the role of microenvironment during embryonic development.
Molecular and cellular endocrinology 2008;288(1-2):111-8.
2008: Aksglaede Lise; Jensen Rikke Beck; Carlsen Elisabeth; Kok Petra; Keenan Daniel M; Veldhuis Johannes; Skakkebaek Niels E; Juul Anders
Increased basal and pulsatile secretion of FSH and LH in young men with 47,XXY or 46,XX karyotypes.
European journal of endocrinology / European Federation of Endocrine Societies 2008;158(6):803-10.
2008: Andersen Helle R; Schmidt Ida M; Grandjean Philippe; Jensen Tina K; Budtz-Jørgensen Esben; Kjaerstad Mia B; Baelum Jesper; Nielsen Jesper B; Skakkebaek Niels E; Main Katharina M
Impaired reproductive development in sons of women occupationally exposed to pesticides during pregnancy.
Environmental health perspectives 2008;116(4):566-72.
2008: Paasch Uwe; Salzbrunn Andrea; Glander Hans Juergen; Plambeck Kai; Salzbrunn Harald; Grunewald Sonja; Stucke Julia; Vierula Matti; Skakkebaek Niels E; Jørgensen Niels
Semen quality in sub-fertile range for a significant proportion of young men from the general German population: a co-ordinated, controlled study of 791 men from Hamburg and Leipzig.
International journal of andrology 2008;31(2):93-102.
2008: Kristensen David M; Nielsen John E; Skakkebaek Niels E; Graem Niels; Jacobsen Grete K; Rajpert-De Meyts Ewa; Leffers Henrik
Presumed pluripotency markers UTF-1 and REX-1 are expressed in human adult testes and germ cell neoplasms.
Human reproduction (Oxford, England) 2008;23(4):775-82.
2008: Sonne Si Brask; Kristensen David Møbjerg; Novotny Guy W; Olesen Inge Ahlmann; Nielsen John E; Skakkebaek Niels E; Rajpert-De Meyts Ewa; Leffers Henrik
Testicular dysgenesis syndrome and the origin of carcinoma in situ testis.
International journal of andrology 2008;31(2):275-87.
2008: Janjua Nadeem Rezaq; Frederiksen Hanne; Skakkebaek Niels E; Wulf Hans Christian; Andersson Anna-Maria
Urinary excretion of phthalates and paraben after repeated whole-body topical application in humans.
International journal of andrology 2008;31(2):118-30.
2008: Jensen Tina Kold; Sobotka Tomás; Hansen Martin A; Pedersen Anette Tønnes; Lutz Wolfgang; Skakkebaek Niels E
Declining trends in conception rates in recent birth cohorts of native Danish women: a possible role of deteriorating male reproductive health.
International journal of andrology 2008;31(2):81-92.
2008: Sharpe Richard M; Skakkebaek Niels E
Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects.
Fertility and sterility 2008;89(2 Suppl):e33-8.
2008: Golub Mari S; Collman Gwen W; Foster Paul M D; Kimmel Carole A; Rajpert-De Meyts Ewa; Reiter Edward O; Sharpe Richard M; Skakkebaek Niels E; Toppari Jorma
Public health implications of altered puberty timing.
Pediatrics 2008;121 Suppl 3():S218-30.
2008: Buck Louis Germaine M; Gray L Earl; Marcus Michele; Ojeda Sergio R; Pescovitz Ora H; Witchel Selma Feldman; Sippell Wolfgang; Abbott David H; Soto Ana; Tyl Rochelle W; Bourguignon Jean-Pierre; Skakkebaek Niels E; Swan Shanna H; Golub Mari S; Wabitsch Martin; Toppari Jorma; Euling Susan Y
Environmental factors and puberty timing: expert panel research needs.
Pediatrics 2008;121 Suppl 3():S192-207.
2008: Euling Susan Y; Selevan Sherry G; Pescovitz Ora Hirsch; Skakkebaek Niels E
Role of environmental factors in the timing of puberty.
Pediatrics 2008;121 Suppl 3():S167-71.
2008: Shen Heqing; Main Katharina M; Andersson Anna-Maria; Damgaard Ida N; Virtanen Helena E; Skakkebaek Niels E; Toppari Jorma; Schramm Karl-Werner
Concentrations of persistent organochlorine compounds in human milk and placenta are higher in Denmark than in Finland.
Human reproduction (Oxford, England) 2008;23(1):201-10.
2008: Aksglaede Lise; Skakkebaek Niels E; Juul Anders
Abnormal sex chromosome constitution and longitudinal growth: serum levels of insulin-like growth factor (IGF)-I, IGF binding protein-3, luteinizing hormone, and testosterone in 109 males with 47,XXY, 47,XYY, or sex-determining region of the Y chromosome (SRY)-positive 46,XX karyotypes.
The Journal of clinical endocrinology and metabolism 2008;93(1):169-76.
2008: Aksglaede L; Molgaard C; Skakkebaek N E; Juul A
Normal bone mineral content but unfavourable muscle/fat ratio in Klinefelter syndrome.
Archives of disease in childhood 2008;93(1):30-4.
2008: Damgaard Ida N; Jensen Tina K; Petersen Jørgen H; Skakkebaek Niels E; Toppari Jorma; Main Katharina M
Risk factors for congenital cryptorchidism in a prospective birth cohort study.
PloS one 2008;3(8):e3051.
2007: Hoei-Hansen Christina E; Rajpert-De Meyts Ewa; Daugaard Gedske; Rorth Mikael; Jorgensen Niels; Skakkebaek Niels E
Does more than one biopsy of the contralateral testis in men with a germ cell tumor add value?
Nature clinical practice. Urology 2007;4(12):652-3.
2007: Andersson Anna-Maria; Jensen Tina K; Juul Anders; Petersen Jørgen H; Jørgensen Torben; Skakkebaek Niels E
Secular decline in male testosterone and sex hormone binding globulin serum levels in Danish population surveys.
The Journal of clinical endocrinology and metabolism 2007;92(12):4696-705.
2007: Juul Anders; Magnusdottir Steinunn; Scheike Thomas; Prytz Sven; Skakkebaek Niels E
Age at voice break in Danish boys: effects of pre-pubertal body mass index and secular trend.
International journal of andrology 2007;30(6):537-42.
2007: Jensen Tina Kold; Jørgensen Niels; Asklund Camilla; Skakkebaek Niels E
Re: "Parental infertility and semen quality in male offspring: a follow-up study".
American journal of epidemiology 2007;166(9):1105.
2007: Jensen Tina K; Jørgensen Niels; Asklund Camilla; Carlsen Elisabeth; Kristensen Tage S; Holm Mette; Skakkebaek Niels Erik
Self-rated health and semen quality among 3,457 young Danish men.
Fertility and sterility 2007;88(5):1366-73.
2007: Bartkova J; Horejsí Z; Sehested M; Nesland J M; Rajpert-De Meyts E; Skakkebaek N E; Stucki M; Jackson S; Lukas J; Bartek J
DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours.
Oncogene 2007;26(53):7414-22.
2007: Main Katharina Maria; Kiviranta Hannu; Virtanen Helena Eeva; Sundqvist Erno; Tuomisto Jouni Tapio; Tuomisto Jouko; Vartiainen Terttu; Skakkebaek Niels Erik; Toppari Jorma
Flame retardants in placenta and breast milk and cryptorchidism in newborn boys.
Environmental health perspectives 2007;115(10):1519-26.
2007: Asklund C; Jørgensen N; Skakkebaek N E; Jensen T K
Increased frequency of reproductive health problems among fathers of boys with hypospadias.
Human reproduction (Oxford, England) 2007;22(10):2639-46.
2007: Rajpert-De Meyts E; Poll S N; Goukasian I; Jeanneau C; Herlihy A S; Bennett E P; Skakkebaek N E; Clausen H; Giwercman A; Mandel U
Changes in the profile of simple mucin-type O-glycans and polypeptide GalNAc-transferases in human testis and testicular neoplasms are associated with germ cell maturation and tumour differentiation.
Virchows Archiv : an international journal of pathology 2007;451(4):805-14.
2007: Bay Katrine; Virtanen Helena E; Hartung Stefan; Ivell Richard; Main Katharina M; Skakkebaek Niels E; Andersson Anna-Maria; Toppari Jorma
Insulin-like factor 3 levels in cord blood and serum from children: effects of age, postnatal hypothalamic-pituitary-gonadal axis activation, and cryptorchidism.
The Journal of clinical endocrinology and metabolism 2007;92(10):4020-7.
2007: Olesen Inge A; Sonne Si Brask; Hoei-Hansen Christina E; Rajpert-DeMeyts Ewa; Skakkebaek Niels E
Environment, testicular dysgenesis and carcinoma in situ testis.
Best practice & research. Clinical endocrinology & metabolism 2007;21(3):462-78.
2007: Aksglaede Lise; Petersen Jørgen H; Main Katharina M; Skakkebaek Niels E; Juul Anders
High normal testosterone levels in infants with non-mosaic Klinefelter's syndrome.
European journal of endocrinology / European Federation of Endocrine Societies 2007;157(3):345-50.
2007: Janjua Nadeem Rezaq; Mortensen Gerda Krogh; Andersson Anna-Maria; Kongshoj Brian; Skakkebaek Niels E; Wulf Hans Christian
Systemic uptake of diethyl phthalate, dibutyl phthalate, and butyl paraben following whole-body topical application and reproductive and thyroid hormone levels in humans.
Environmental science & technology 2007;41(15):5564-70.
2007: Olesen Inge A; Hoei-Hansen Christina E; Skakkebaek Niels E; Petersen Jørgen H; Rajpert-De Meyts Ewa; Jørgensen Niels
Testicular carcinoma in situ in subfertile Danish men.
International journal of andrology 2007;30(4):406-11; discussion 412.
2007: Skakkebaek N E; Rajpert-De Meyts E; Jørgensen N; Main K M; Leffers H; Andersson A-M; Juul A; Jensen T K; Toppari J
Testicular cancer trends as 'whistle blowers' of testicular developmental problems in populations.
International journal of andrology 2007;30(4):198-204; discussion 204-5.
2007: Joensen Ulla N; Jørgensen Niels; Skakkebaek Niels E
Testicular dysgenesis syndrome and carcinoma in situ of the testes.
Nature clinical practice. Urology 2007;4(8):402-3.
2007: Bartkova J; Rajpert-De Meyts E; Skakkebaek N E; Lukas J; Bartek J
DNA damage response in human testes and testicular germ cell tumours: biology and implications for therapy.
International journal of andrology 2007;30(4):282-91; discussion 291.
2007: Novotny G W; Nielsen J E; Sonne S B; Skakkebaek N E; Rajpert-De Meyts E; Leffers H
Analysis of gene expression in normal and neoplastic human testis: new roles of RNA.
International journal of andrology 2007;30(4):316-26; discussion 326-7.
2007: Sørensen K; Andersson A M; Skakkebaek N E; Juul A
Serum sex hormone-binding globulin levels in healthy children and girls with precocious puberty before and during gonadotropin-releasing hormone agonist treatment.
The Journal of clinical endocrinology and metabolism 2007;92(8):3189-96.
2007: Almstrup Kristian; Leffers Henrik; Lothe Ragnhild A; Skakkebaek Niels E; Sonne Si B; Nielsen John E; Rajpert-De Meyts Ewa; Skotheim Rolf I
Improved gene expression signature of testicular carcinoma in situ.
International journal of andrology 2007;30(4):292-302; discussion 303.
2007: Frederiksen Hanne; Skakkebaek Niels E; Andersson Anna-Maria
Metabolism of phthalates in humans.
Molecular nutrition & food research 2007;51(7):899-911.
2007: Juul A; Aksglaede L; Lund A M; Duno M; Skakkebaek N E; Rajpert-De Meyts E
Preserved fertility in a non-mosaic Klinefelter patient with a mutation in the fibroblast growth factor receptor 3 gene: case report.
Human reproduction (Oxford, England) 2007;22(7):1907-11.
2007: Teilmann Grete; Boas Malene; Petersen Jørgen H; Main Katharina M; Gormsen Magdalena; Damgaard Karen; Brocks Vibeke; Skakkebaek Niels E; Jensen Tina Kold
Early pituitary-gonadal activation before clinical signs of puberty in 5- to 8-year-old adopted girls: a study of 99 foreign adopted girls and 93 controls.
The Journal of clinical endocrinology and metabolism 2007;92(7):2538-44.
2007: Mau Kai Claudia; Main Katharina M; Andersen Anders Nyboe; Loft Anne; Skakkebaek Niels E; Juul Anders
Reduced serum testosterone levels in infant boys conceived by intracytoplasmic sperm injection.
The Journal of clinical endocrinology and metabolism 2007;92(7):2598-603.
2007: Virtanen Helena E; Cortes Dina; Rajpert-De Meyts Ewa; Ritzén E Martin; Nordenskjöld Agneta; Skakkebaek Niels E; Toppari Jorma
Development and descent of the testis in relation to cryptorchidism.
Acta paediatrica (Oslo, Norway : 1992) 2007;96(5):622-7.
2007: Toppari Jorma; Kaleva Marko; Virtanen Helena E; Main Katharina M; Skakkebaek Niels E
Luteinizing hormone in testicular descent.
Molecular and cellular endocrinology 2007;269(1-2):34-7.
2007: Klose Marianne; Lange Martin; Rasmussen Aase Krogh; Skakkebaek Niels Erik; Hilsted Linda; Haug Egil; Andersen Marianne; Feldt-Rasmussen Ulla
Factors influencing the adrenocorticotropin test: role of contemporary cortisol assays, body composition, and oral contraceptive agents.
The Journal of clinical endocrinology and metabolism 2007;92(4):1326-33.
2007: Novotny G W; Sonne S B; Nielsen J E; Jonstrup S P; Hansen M A; Skakkebaek N E; Rajpert-De Meyts E; Kjems J; Leffers H
Translational repression of E2F1 mRNA in carcinoma in situ and normal testis correlates with expression of the miR-17-92 cluster.
Cell death and differentiation 2007;14(4):879-82.
2007: Shen Heqing; Main Katharina M; Virtanen Helena E; Damggard Ida N; Haavisto Anne-Maarit; Kaleva M; Boisen K A; Schmidt Ida M; Chellakooty Marla; Skakkebaek Niels E; Toppari Jorma; Schramm Karl-Werner
From mother to child: investigation of prenatal and postnatal exposure to persistent bioaccumulating toxicants using breast milk and placenta biomonitoring.
Chemosphere 2007;67(9):S256-62.
2007: Jensen Tina Kold; Jørgensen Niels; Asklund Camilla; Carlsen Elisabeth; Holm Mette; Skakkebaek Niels E
Fertility treatment and reproductive health of male offspring: a study of 1,925 young men from the general population.
American journal of epidemiology 2007;165(5):583-90.
2007: Asklund Camilla; Jensen T K; Jørgensen N; Tabor A; Sperling L; Skakkebaek N E
Twin pregnancy possibly associated with high semen quality.
Human reproduction (Oxford, England) 2007;22(3):751-5.
2007: Damgaard Ida N; Jensen Tina K; Petersen Jørgen H; Skakkebaek Niels E; Toppari Jorma; Main Katharina M
Cryptorchidism and maternal alcohol consumption during pregnancy.
Environmental health perspectives 2007;115(2):272-7.
2007: Aksglaede Lise; Andersson Anna-Maria; Jørgensen Niels; Jensen Tina Kold; Carlsen Elisabeth; McLachlan Robert I; Skakkebaek Niels E; Petersen Jørgen Holm; Juul Anders
Primary testicular failure in Klinefelter's syndrome: the use of bivariate luteinizing hormone-testosterone reference charts.
Clinical endocrinology 2007;66(2):276-81.
2007: Hoei-Hansen C E; Carlsen E; Jorgensen N; Leffers H; Skakkebaek N E; Rajpert-De Meyts E
Towards a non-invasive method for early detection of testicular neoplasia in semen samples by identification of fetal germ cell-specific markers.
Human reproduction (Oxford, England) 2007;22(1):167-73.
2006: Toppari J; Virtanen H; Skakkebaek N E; Main K M
Environmental effects on hormonal regulation of testicular descent.
The Journal of steroid biochemistry and molecular biology 2006;102(1-5):184-6.
2006: Virtanen Helena E; Tapanainen Anna E; Kaleva Marko M; Suomi Anne-Maarit; Main Katharina M; Skakkebaek Niels E; Toppari Jorma
Mild gestational diabetes as a risk factor for congenital cryptorchidism.
The Journal of clinical endocrinology and metabolism 2006;91(12):4862-5.
2006: Kai Claudia Mau; Main Katharina M; Andersen Anders Nyboe; Loft Anne; Chellakooty Marla; Skakkebaek Niels E; Juul Anders
Serum insulin-like growth factor-I (IGF-I) and growth in children born after assisted reproduction.
The Journal of clinical endocrinology and metabolism 2006;91(11):4352-60.
2006: Aitken R John; Skakkebaek Niels E; Roman Shaun D
Male reproductive health and the environment.
The Medical journal of Australia 2006;185(8):414-5.
2006: Teilmann Grete; Pedersen Carsten B; Skakkebaek Niels E; Jensen Tina Kold
Increased risk of precocious puberty in internationally adopted children in Denmark.
Pediatrics 2006;118(2):e391-9.
2006: Sonne Si Brask; Herlihy Amy S; Hoei-Hansen Christina E; Nielsen John E; Almstrup Kristian; Skakkebaek Niels E; Marks Alexander; Leffers Henrik; Rajpert-De Meyts Ewa
Identity of M2A (D2-40) antigen and gp36 (Aggrus, T1A-2, podoplanin) in human developing testis, testicular carcinoma in situ and germ-cell tumours.
Virchows Archiv : an international journal of pathology 2006;449(2):200-6.
2006: Sonne Si B; Hoei-Hansen Christina E; Nielsen John E; Herlihy Amy S; Andersson Anna-Maria; Almstrup Kristian; Daugaard Gedske; Skakkebaek Niels E; Leffers Henrik; Rajpert-De Meyts Ewa
CDH1 (E-cadherin) in testicular germ cell neoplasia: suppressed translation of mRNA in pre-invasive carcinoma in situ but increased protein levels in advanced tumours.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2006;114(7-8):549-58.
2006: Damgaard Ida N; Skakkebaek Niels E; Toppari Jorma; Virtanen Helena E; Shen Heqing; Schramm Karl-Werner; Petersen Jørgen H; Jensen Tina K; Main Katharina M;
Persistent pesticides in human breast milk and cryptorchidism.
Environmental health perspectives 2006;114(7):1133-8.
2006: Aksglaede Lise; Juul Anders; Leffers Henrik; Skakkebaek Niels E; Andersson Anna-Maria
The sensitivity of the child to sex steroids: possible impact of exogenous estrogens.
Human reproduction update 2006;12(4):341-9.
2006: Main Katharina M; Toppari Jorma; Suomi Anne-Maarit; Kaleva Marko; Chellakooty Marla; Schmidt Ida M; Virtanen Helena E; Boisen Kirsten A; Kai Claudia M; Damgaard Ida N; Skakkebaek Niels E
Larger testes and higher inhibin B levels in Finnish than in Danish newborn boys.
The Journal of clinical endocrinology and metabolism 2006;91(7):2732-7.
2006: Boas Malene; Feldt-Rasmussen Ulla; Skakkebaek Niels E; Main Katharina M
Environmental chemicals and thyroid function.
European journal of endocrinology / European Federation of Endocrine Societies 2006;154(5):599-611.
2006: Hansen Martin A; Nielsen John E; Tanaka Masami; Almstrup Kristian; Skakkebaek Niels E; Leffers Henrik
Identification and expression profiling of 10 novel spermatid expressed CYPT genes.
Molecular reproduction and development 2006;73(5):568-79.
2006: Hoei-Hansen C E; Sehested A; Juhler M; Lau Y-F C; Skakkebaek N E; Laursen H; Rajpert-de Meyts E
New evidence for the origin of intracranial germ cell tumours from primordial germ cells: expression of pluripotency and cell differentiation markers.
The Journal of pathology 2006;209(1):25-33.
2006: Leffers H; Navarro V M; Nielsen John E; Mayen A; Pinilla L; Dalgaard M; Malagon M M; Castaño J P; Skakkebaek N E; Aguilar E; Tena-Sempere M
Increased expression of alpha- and beta-globin mRNAs at the pituitary following exposure to estrogen during the critical period of neonatal sex differentiation in the rat.
The Journal of steroid biochemistry and molecular biology 2006;99(1):33-43.
2006: Bay Katrine; Asklund Camilla; Skakkebaek Niels E; Andersson Anna-Maria
Testicular dysgenesis syndrome: possible role of endocrine disrupters.
Best practice & research. Clinical endocrinology & metabolism 2006;20(1):77-90.
2006: Suomi Anne-Maarit; Main Katharina M; Kaleva Marko; Schmidt Ida Maria; Chellakooty Marla; Virtanen Helena E; Boisen Kirsten A; Damgaard Ida N; Kai Claudia Mau; Skakkebaek Niels E; Toppari Jorma
Hormonal changes in 3-month-old cryptorchid boys.
The Journal of clinical endocrinology and metabolism 2006;91(3):953-8.
2006: Chellakooty M; Juul A; Boisen K A; Damgaard I N; Kai C M; Schmidt I M; Petersen J H; Skakkebaek N E; Main K M
A prospective study of serum insulin-like growth factor I (IGF-I) and IGF-binding protein-3 in 942 healthy infants: associations with birth weight, gender, growth velocity, and breastfeeding.
The Journal of clinical endocrinology and metabolism 2006;91(3):820-6.
2006: Juul A; Teilmann G; Scheike T; Hertel N T; Holm K; Laursen E M; Main K M; Skakkebaek N E
Pubertal development in Danish children: comparison of recent European and US data.
International journal of andrology 2006;29(1):247-55; discussion 286-90.
2006: Almstrup Kristian; Sonne Si Brask; Hoei-Hansen Christina E; Ottesen Anne Marie; Nielsen John E; Skakkebaek Niels E; Leffers Henrik; Rajpert-De Meyts Ewa
From embryonic stem cells to testicular germ cell cancer-- should we be concerned?
International journal of andrology 2006;29(1):211-8.
2006: Lottrup G; Andersson A-M; Leffers H; Mortensen G K; Toppari J; Skakkebaek N E; Main K M
Possible impact of phthalates on infant reproductive health.
International journal of andrology 2006;29(1):172-80; discussion 181-5.
2006: Jørgensen Niels; Asklund Camilla; Carlsen Elisabeth; Skakkebaek Niels E
Coordinated European investigations of semen quality: results from studies of Scandinavian young men is a matter of concern.
International journal of andrology 2006;29(1):54-61; discussion 105-8.
2006: Skakkebaek Niels E; Jørgensen Niels; Main Katharina M; Rajpert-De Meyts Ewa; Leffers Henrik; Andersson Anna-Maria; Juul Anders; Carlsen Elisabeth; Mortensen Gerda Krog; Jensen Tina Kold; Toppari Jorma
Is human fecundity declining?
International journal of andrology 2006;29(1):2-11.
2006: Main Katharina M; Mortensen Gerda K; Kaleva Marko M; Boisen Kirsten A; Damgaard Ida N; Chellakooty Marla; Schmidt Ida M; Suomi Anne-Maarit; Virtanen Helena E; Petersen Dajørgen Vid H; Andersson Anna-Maria; Toppari Jorma; Skakkebaek Niels E
Human breast milk contamination with phthalates and alterations of endogenous reproductive hormones in infants three months of age.
Environmental health perspectives 2006;114(2):270-6.
2006: Boas Malene; Boisen Kirsten A; Virtanen Helena E; Kaleva Marko; Suomi Anne-Maarit; Schmidt Ida M; Damgaard Ida N; Kai Claudia M; Chellakooty Marla; Skakkebaek Niels E; Toppari Jorma; Main Katharina M
Postnatal penile length and growth rate correlate to serum testosterone levels: a longitudinal study of 1962 normal boys.
European journal of endocrinology / European Federation of Endocrine Societies 2006;154(1):125-9.
2006: Aksglaede Lise; Wikström Anne M; Rajpert-De Meyts Ewa; Dunkel Leo; Skakkebaek Niels E; Juul Anders
Natural history of seminiferous tubule degeneration in Klinefelter syndrome.
Human reproduction update 2006;12(1):39-48.
2006: Shen Heqing; Virtanen H E; Main Katharina M; Kaleva M; Andersson A M; Skakkebaek Niels E; Toppari Jorma; Schramm Karl-Werner
Enantiomeric ratios as an indicator of exposure processes for persistent pollutants in human placentas.
Chemosphere 2006;62(3):390-5.
2006: Main K M; Jensen R B; Asklund C; Høi-Hansen C E; Skakkebaek N E
Low birth weight and male reproductive function.
Hormone research 2006;65 Suppl 3():116-22.
2006: Ekbom Pia; Damm Peter; Andersson Anna-Maria; Skakkebaek Niels Erik; Feldt-Rasmussen Ulla; Mathiesen Elisabeth R
Serum levels of activin A and inhibin A are not related to the increased susceptibility to pre-eclampsia in type I diabetic pregnancies.
Acta obstetricia et gynecologica Scandinavica 2006;85(2):143-7.
2005: Skakkebaek N E; Jørgensen N
Testicular dysgenesis and fertility.
Andrologia 2005;37(6):217-8.
2005: Teilmann Grete; Pedersen Carsten B; Jensen Tina Kold; Skakkebaek Niels E; Juul Anders
Prevalence and incidence of precocious pubertal development in Denmark: an epidemiologic study based on national registries.
Pediatrics 2005;116(6):1323-8.
2005: Hoei-Hansen Christina E; Sommer Peter; Meyts Ewa Rajpert-De; Skakkebaek Niels E
A rare diagnosis: testicular dysgenesis with carcinoma in situ detected in a patient with ultrasonic microlithiasis.
Asian journal of andrology 2005;7(4):445-7.
2005: Bang A K; Carlsen E; Holm M; Petersen J H; Skakkebaek N E; Jørgensen N
A study of finger lengths, semen quality and sex hormones in 360 young men from the general Danish population.
Human reproduction (Oxford, England) 2005;20(11):3109-13.
2005: Almstrup Kristian; Ottesen Anne Marie; Sonne Si Brask; Hoei-Hansen Christina E; Leffers Henrik; Rajpert-De Meyts Ewa; Skakkebaek Niels E
Genomic and gene expression signature of the pre-invasive testicular carcinoma in situ.
Cell and tissue research 2005;322(1):159-65.
2005: Kaleva Marko; Virtanen Helena; Haavisto Anne-Maarit; Main Katharina; Skakkebaek Niels E; Huhtaniemi Ilpo; Irjala Kerttu; Toppari Jorma
Does variant luteinizing hormone (V-LH) predispose to improper testicular position in late pregnancy?
Pediatric research 2005;58(3):447-50.
2005: Hoei-Hansen C E; Almstrup K; Nielsen J E; Brask Sonne S; Graem N; Skakkebaek N E; Leffers H; Rajpert-De Meyts E
Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumours.
Histopathology 2005;47(1):48-56.
2005: Shen H; Main K M; Kaleva M; Virtanen H; Haavisto A-M; Skakkebaek N E; Toppari J; Schramm K-W
Prenatal organochlorine pesticides in placentas from Finland: exposure of male infants born during 1997-2001.
Placenta 2005;26(6):512-4.
2005: Boisen K A; Chellakooty M; Schmidt I M; Kai C M; Damgaard I N; Suomi A-M; Toppari J; Skakkebaek N E; Main K M
Hypospadias in a cohort of 1072 Danish newborn boys: prevalence and relationship to placental weight, anthropometrical measurements at birth, and reproductive hormone levels at three months of age.
The Journal of clinical endocrinology and metabolism 2005;90(7):4041-6.
2005: Preiksa R T; Zilaitiene B; Matulevicius V; Skakkebaek N E; Petersen J H; Jørgensen N; Toppari J
Higher than expected prevalence of congenital cryptorchidism in Lithuania: a study of 1204 boys at birth and 1 year follow-up.
Human reproduction (Oxford, England) 2005;20(7):1928-32.
2005: Mortensen Gerda K; Main Katharina M; Andersson Anna-Maria; Leffers Henrik; Skakkebaek Niels E
Determination of phthalate monoesters in human milk, consumer milk, and infant formula by tandem mass spectrometry (LC-MS-MS).
Analytical and bioanalytical chemistry 2005;382(4):1084-92.
2005: Bartkova Jirina; Bakkenist Christopher J; Rajpert-De Meyts Ewa; Skakkebaek Niels E; Sehested Maxwell; Lukas Jiri; Kastan Michael B; Bartek Jiri
ATM activation in normal human tissues and testicular cancer.
Cell cycle (Georgetown, Tex.) 2005;4(6):838-45.
2005: Hoei-Hansen C E; Rajpert-De Meyts E; Daugaard G; Skakkebaek N E
Carcinoma in situ testis, the progenitor of testicular germ cell tumours: a clinical review.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16(6):863-8.
2005: Bay K; Hartung S; Ivell R; Schumacher M; Jürgensen D; Jorgensen N; Holm M; Skakkebaek N E; Andersson A-M
Insulin-like factor 3 serum levels in 135 normal men and 85 men with testicular disorders: relationship to the luteinizing hormone-testosterone axis.
The Journal of clinical endocrinology and metabolism 2005;90(6):3410-8.
2005: Almstrup K; Hoei-Hansen C E; Nielsen J E; Wirkner U; Ansorge W; Skakkebaek N E; Rajpert-De Meyts E; Leffers H
Genome-wide gene expression profiling of testicular carcinoma in situ progression into overt tumours.
British journal of cancer 2005;92(10):1934-41.
2005: Carlsen Elisabeth; Swan Shanna H; Petersen Jørgen Holm; Skakkebaek Niels E
Longitudinal changes in semen parameters in young Danish men from the Copenhagen area.
Human reproduction (Oxford, England) 2005;20(4):942-9.
2005: Overlie Inger; Mørkrid Lars; Andersson Anna-Maria; Skakkebaek Niels E; Moen Mette H; Holte Arne
Inhibin A and B as markers of menopause: a five-year prospective longitudinal study of hormonal changes during the menopausal transition.
Acta obstetricia et gynecologica Scandinavica 2005;84(3):281-5.
2005: Hoei-Hansen C E; Rajpert-De Meyts E; Carlsen E; Almstrup K; Leffers H; Skakkebaek N E
A subfertile patient diagnosed with testicular carcinoma in situ by immunocytological staining for AP-2gamma in semen samples: case report.
Human reproduction (Oxford, England) 2005;20(3):579-82.
2005: Kaleva Marko; Virtanen Helena E; Haavisto Anne-Maarit; Main Katharina M; Reunanen Mikko; Skakkebaek Niels E; Toppari Jorma
Circannual rhythm in the incidence of cryptorchidism in Finland.
International journal of andrology 2005;28(1):53-7.
2005: Jensen Rikke Beck; Jeppesen Katrine Arp; Vielwerth Signe; Michaelsen Kim Fleischer; Main Katharina M; Skakkebaek Niels E; Juul Anders
Insulin-like growth factor I (IGF-I) and IGF-binding protein 3 as diagnostic markers of growth hormone deficiency in infancy.
Hormone research 2005;63(1):15-21.
2004: Hoei-Hansen Christina E; Nielsen John E; Almstrup Kristian; Sonne Si Brask; Graem Niels; Skakkebaek Niels E; Leffers Henrik; Rajpert-De Meyts Ewa
Transcription factor AP-2gamma is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8521-30.
2004: Boisen Kirsten A; Kaleva Marko; Main Katharina M; Virtanen Helena; Haavisto Anne-Maarit; Schmidt Ida Maria; Chellakooty Marla; Damgaard Ida Norgil; Mau Claudia; Reunanen Mikko; Skakkebaek Niels E; Toppari Jorma
[High and increasing prevalence of cryptorchidism in Denmark]
Ugeskrift for laeger 2004;166(48):4372-5.
2004: Jensen Tina Kold; Andersson Anne-Maria; Jørgensen Niels; Andersen Anne-Grethe; Carlsen Elisabeth; Petersen Jørgen Holm; Skakkebaek Niels E
Body mass index in relation to semen quality and reproductive hormones among 1,558 Danish men.
Fertility and sterility 2004;82(4):863-70.
2004: Henriksen Tine Brink; Hjollund Niels Henrik; Jensen Tina Kold; Bonde Jens Peter; Andersson Anna-Maria; Kolstad Henrik; Ernst Erik; Giwercman Aleksander; Skakkebaek Niels Erik; Olsen Jørn
Alcohol consumption at the time of conception and spontaneous abortion.
American journal of epidemiology 2004;160(7):661-7.
2004: Bay Katrine; Andersson Anna-Maria; Skakkebaek Niels E
Estradiol levels in prepubertal boys and girls--analytical challenges.
International journal of andrology 2004;27(5):266-73.
2004: Carlsen Elisabeth; Petersen Jørgen Holm; Andersson Anna-Maria; Skakkebaek Niels E
Effects of ejaculatory frequency and season on variations in semen quality.
Fertility and sterility 2004;82(2):358-66.
2004: Skakkebaek Niels E
Testicular dysgenesis syndrome: new epidemiological evidence.
International journal of andrology 2004;27(4):189-91.
2004: Almstrup Kristian; Hoei-Hansen Christina E; Wirkner Ute; Blake Jonathon; Schwager Christian; Ansorge Wilhelm; Nielsen John E; Skakkebaek Niels E; Rajpert-De Meyts Ewa; Leffers Henrik
Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling.
Cancer research 2004;64(14):4736-43.
2004: Andersson A-M; Jørgensen N; Frydelund-Larsen L; Rajpert-De Meyts E; Skakkebaek N E
Impaired Leydig cell function in infertile men: a study of 357 idiopathic infertile men and 318 proven fertile controls.
The Journal of clinical endocrinology and metabolism 2004;89(7):3161-7.
2004: Janjua Nadeem Rezaq; Mogensen Brian; Andersson Anna-Maria; Petersen Jørgen Holm; Henriksen Mette; Skakkebaek Niels E; Wulf Hans Christian
Systemic absorption of the sunscreens benzophenone-3, octyl-methoxycinnamate, and 3-(4-methyl-benzylidene) camphor after whole-body topical application and reproductive hormone levels in humans.
The Journal of investigative dermatology 2004;123(1):57-61.
2004: Andersson Anna-Maria; Petersen Jørgen H; Jørgensen Niels; Jensen Tina K; Skakkebaek Niels E
Serum inhibin B and follicle-stimulating hormone levels as tools in the evaluation of infertile men: significance of adequate reference values from proven fertile men.
The Journal of clinical endocrinology and metabolism 2004;89(6):2873-9.
2004: Hoei-Hansen C E; Nielsen J E; Almstrup K; Hansen M A; Skakkebaek N E; Rajpert-DeMeyts E; Leffers H
Identification of genes differentially expressed in testes containing carcinoma in situ.
Molecular human reproduction 2004;10(6):423-31.
2004: Rajpert-De Meyts Ewa; Hanstein Regina; Jørgensen Niels; Graem Niels; Vogt Peter H; Skakkebaek Niels E
Developmental expression of POU5F1 (OCT-3/4) in normal and dysgenetic human gonads.
Human reproduction (Oxford, England) 2004;19(6):1338-44.
2004: Almstrup Kristian; Nielsen John E; Hansen Martin A; Tanaka Masami; Skakkebaek Niels E; Leffers Henrik
Analysis of cell-type-specific gene expression during mouse spermatogenesis.
Biology of reproduction 2004;70(6):1751-61.
2004: Asklund C; Jørgensen N; Kold Jensen T; Skakkebaek N E
Biology and epidemiology of testicular dysgenesis syndrome.
BJU international 2004;93 Suppl 3():6-11.
2004: Boisen K A; Kaleva M; Main K M; Virtanen H E; Haavisto A-M; Schmidt I M; Chellakooty M; Damgaard I N; Mau C; Reunanen M; Skakkebaek N E; Toppari J
Difference in prevalence of congenital cryptorchidism in infants between two Nordic countries.
Lancet 2004;363(9417):1264-9.
2004: Ottesen Anne Marie; Larsen Jacob; Gerdes Tommy; Larsen Jørgen K; Lundsteen Claes; Skakkebaek Niels E; Rajpert-De Meyts Ewa
Cytogenetic investigation of testicular carcinoma in situ and early seminoma by high-resolution comparative genomic hybridization analysis of subpopulations flow sorted according to DNA content.
Cancer genetics and cytogenetics 2004;149(2):89-97.
2004: Ottesen A M; Rajpert-De Meyts E; Holm M; Andersen I-L F; Vogt P H; Lundsteen C; Skakkebaek N E
Cytogenetic and molecular analysis of a family with three brothers afflicted with germ-cell cancer.
Clinical genetics 2004;65(1):32-9.
2004: Chellakooty M; Vangsgaard K; Larsen T; Scheike T; Falck-Larsen J; Legarth J; Andersson A M; Main K M; Skakkebaek N E; Juul A
A longitudinal study of intrauterine growth and the placental growth hormone (GH)-insulin-like growth factor I axis in maternal circulation: association between placental GH and fetal growth.
The Journal of clinical endocrinology and metabolism 2004;89(1):384-91.
2004: Jensen Tina Kold; Jørgensen Niels; Punab Margus; Haugen Trine B; Suominen Jyrki; Zilaitiene Birute; Horte Antero; Andersen Anne-Grethe; Carlsen Elisabeth; Magnus Øystein; Matulevicius Valentinas; Nermoen Ingrid; Vierula Matti; Keiding Niels; Toppari Jorma; Skakkebaek Niels E
Association of in utero exposure to maternal smoking with reduced semen quality and testis size in adulthood: a cross-sectional study of 1,770 young men from the general population in five European countries.
American journal of epidemiology 2004;159(1):49-58.
2004: Jensen Martin; Leffers Henrik; Petersen Jørgen H; Nyboe Andersen Anders; Jørgensen Niels; Carlsen Elisabeth; Jensen Tina Kold; Skakkebaek Niels E; Rajpert-De Meyts Ewa
Frequent polymorphism of the mitochondrial DNA polymerase gamma gene (POLG) in patients with normal spermiograms and unexplained subfertility.
Human reproduction (Oxford, England) 2004;19(1):65-70.
2004: Sonne S B; Hoei-Hansen C E; Fisher J S; Leffers H; Rajpert-de Meyts E; Skakkebaek N E
Do environmental factors play a role in the aetiology of carcinoma in situ testis and the testicular dysgenesis syndrome?
Verhandlungen der Deutschen Gesellschaft für Pathologie 2004;88():144-51.
2003: Simpson Joe Leigh; de la Cruz Felix; Swerdloff Ronald S; Samango-Sprouse Carole; Skakkebaek Niels E; Graham John M; Hassold Terry; Aylstock Melissa; Meyer-Bahlburg Heino F L; Willard Huntington F; Hall Judith G; Salameh Wael; Boone Kyle; Staessen Catherine; Geschwind Dan; Giedd Jay; Dobs Adrian S; Rogol Alan; Brinton Bonnie; Paulsen C Alvin
Klinefelter syndrome: expanding the phenotype and identifying new research directions.
Genetics in medicine : official journal of the American College of Medical Genetics 2003;5(6):460-8.
2003: Jørgensen Marianne Hørby; Ott Peter; Juul Anders; Skakkebaek Niels Erik; Michaelsen Kim Fleischer
Does breast feeding influence liver biochemistry?
Journal of pediatric gastroenterology and nutrition 2003;37(5):559-65.
2003: Parent Anne-Simone; Teilmann Grete; Juul Anders; Skakkebaek Niels E; Toppari Jorma; Bourguignon Jean-Pierre
The timing of normal puberty and the age limits of sexual precocity: variations around the world, secular trends, and changes after migration.
Endocrine reviews 2003;24(5):668-93.
2003: Carlsen Elisabeth; Andersson Anna-Maria; Petersen Jørgen Holm; Skakkebaek Niels E
History of febrile illness and variation in semen quality.
Human reproduction (Oxford, England) 2003;18(10):2089-92.
2003: Holm Mette; Hoei-Hansen Christina E; Rajpert-De Meyts Ewa; Skakkebaek Niels E
Increased risk of carcinoma in situ in patients with testicular germ cell cancer with ultrasonic microlithiasis in the contralateral testicle.
The Journal of urology 2003;170(4 Pt 1):1163-7.
2003: Ottesen Anne Marie; Skakkebaek Niels E; Lundsteen Claes; Leffers Henrik; Larsen Jacob; Rajpert-De Meyts Ewa
High-resolution comparative genomic hybridization detects extra chromosome arm 12p material in most cases of carcinoma in situ adjacent to overt germ cell tumors, but not before the invasive tumor development.
Genes, chromosomes & cancer 2003;38(2):117-25.
2003: Frydelund-Larsen Lone; Vogt Peter H; Leffers Henrik; Schadwinkel Alexandra; Daugaard Gedske; Skakkebaek Niels E; Rajpert-De Meyts Ewa
No AZF deletion in 160 patients with testicular germ cell neoplasia.
Molecular human reproduction 2003;9(9):517-21.
2003: Chellakooty M; Schmidt I M; Haavisto A M; Boisen K A; Damgaard I N; Mau C; Petersen J H; Juul A; Skakkebaek N E; Main K M
Inhibin A, inhibin B, follicle-stimulating hormone, luteinizing hormone, estradiol, and sex hormone-binding globulin levels in 473 healthy infant girls.
The Journal of clinical endocrinology and metabolism 2003;88(8):3515-20.
2003: Hoei-Hansen Christina E; Holm Mette; Rajpert-De Meyts Ewa; Skakkebaek Niels E
Histological evidence of testicular dysgenesis in contralateral biopsies from 218 patients with testicular germ cell cancer.
The Journal of pathology 2003;200(3):370-4.
2003: Bouloux Pierre-Marc G; Nieschlag Eberhard; Burger Henry G; Skakkebaek Niels E; Wu Frederick C W; Handelsman David J; Baker Gordon H W; Ochsenkuehn Robert; Syska Annemarie; McLachlan Robert I; Giwercman Aleksander; Conway Ann J; Turner Leo; van Kuijk Jacqueline H M; Voortman Gerrit
Induction of spermatogenesis by recombinant follicle-stimulating hormone (puregon) in hypogonadotropic azoospermic men who failed to respond to human chorionic gonadotropin alone.
Journal of andrology 2003;24(4):604-11.
2003: Bartkova Jirina; Lukas Claudia; Sørensen Claus S; Meyts Ewa Rajpert-De; Skakkebaek Niels E; Lukas Jiri; Bartek Jiri
Deregulation of the RB pathway in human testicular germ cell tumours.
The Journal of pathology 2003;200(2):149-56.
2003: Rajpert-De Meyts E; Jacobsen G K; Bartkova J; Aubry F; Samson M; Bartek J; Skakkebaek N E
The immunohistochemical expression pattern of Chk2, p53, p19INK4d, MAGE-A4 and other selected antigens provides new evidence for the premeiotic origin of spermatocytic seminoma.
Histopathology 2003;42(3):217-26.
2003: Holm Mette; Rajpert-De Meyts Ewa; Andersson Anna-Maria; Skakkebaek Niels E
Leydig cell micronodules are a common finding in testicular biopsies from men with impaired spermatogenesis and are associated with decreased testosterone/LH ratio.
The Journal of pathology 2003;199(3):378-86.
2003: Andersson Anna-Maria; Carlsen Elisabeth; Petersen Jørgen Holm; Skakkebaek Niels Erik
Variation in levels of serum inhibin B, testosterone, estradiol, luteinizing hormone, follicle-stimulating hormone, and sex hormone-binding globulin in monthly samples from healthy men during a 17-month period: possible effects of seasons.
The Journal of clinical endocrinology and metabolism 2003;88(2):932-7.
2003: Christiansen P; Andersson A-M; Skakkebaek N E
Longitudinal studies of inhibin B levels in boys and young adults with Klinefelter syndrome.
The Journal of clinical endocrinology and metabolism 2003;88(2):888-91.
2003: Bartkova Jirina; Rajpert-De Meyts Ewa; Skakkebaek Niels E; Lukas Jiri; Bartek Jiri
Deregulation of the G1/S-phase control in human testicular germ cell tumours.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003;111(1):252-65; discussion 265-6.
2003: Rajpert-De Meyts Ewa; Bartkova Jirina; Samson Michel; Hoei-Hansen Christina E; Frydelund-Larsen Lone; Bartek Jiri; Skakkebaek Niels E
The emerging phenotype of the testicular carcinoma in situ germ cell.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003;111(1):267-78; discussion 278-9.
2003: Petersen Peter Meidahl; Daugaard Gedske; Rørth Mikael; Skakkebaek Niels E
Endocrine function in patients treated for carcinoma in situ in the testis with irradiation.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003;111(1):93-8; discussion 98-9.
2003: Skakkebaek Niels E; Holm Mette; Hoei-Hansen Christina; Jørgensen Niels; Rajpert-De Meyts Ewa
Association between testicular dysgenesis syndrome (TDS) and testicular neoplasia: evidence from 20 adult patients with signs of maldevelopment of the testis.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003;111(1):1-9; discussion 9-11.
2003: Lønberg Ulla; Damm Peter; Andersson Anna-Maria; Main Katharina Maria; Chellakooty Marla; Lauenborg Jeannet; Skakkebaek Niels E; Juul Anders
Increase in maternal placental growth hormone during pregnancy and disappearance during parturition in normal and growth hormone-deficient pregnancies.
American journal of obstetrics and gynecology 2003;188(1):247-51.
2003: Jensen Rikke Bodin Beck; Chellakooty Marla; Vielwerth Signe; Vaag Allan; Larsen Torben; Greisen Gorm; Skakkebaek Niels E; Scheike Thomas; Juul Anders
Intrauterine growth retardation and consequences for endocrine and cardiovascular diseases in adult life: does insulin-like growth factor-I play a role?
Hormone research 2003;60 Suppl 3():136-48.
2003: Skakkebaek Niels E
Testicular dysgenesis syndrome.
Hormone research 2003;60 Suppl 3():49.
2003: Nielsen J E; Hansen M A; Jørgensen M; Tanaka M; Almstrup K; Skakkebaek N E; Leffers H
Germ cell differentiation-dependent and stage-specific expression of LANCL1 in rodent testis.
European journal of histochemistry : EJH 2003;47(3):215-22.
2003: Rajpert-De Meyts Ewa; Toppari Jorma; Høi-Hansen Christina E; Müller Jørn; Skakkebaek Niels E
Testicular neoplasia in childhood and adolescence.
Endocrine development 2003;5():110-23.
2002: Jørgensen Jens O L; Nørrelund Helene; Vahl Nina; Juul Anders; Skakkebaek Niels E; Christiansen Jens Sandahl
Continuation of growth hormone therapy versus placebo in transition-phase patients with growth hormone deficiency: impact on body composition, insulin sensitivity, and thyroid function.
Journal of pediatric endocrinology & metabolism : JPEM 2002;15 Suppl 5():1355-60.
2002: Frydelund-Larsen Lone; Krausz Csilla; Leffers Henrik; Andersson Anna Maria; Carlsen Elisabeth; Bangsboell Susanne; McElreavey Ken; Skakkebaek Niels E; Rajpert-De Meyts Ewa
Inhibin B: a marker for the functional state of the seminiferous epithelium in patients with azoospermia factor C microdeletions.
The Journal of clinical endocrinology and metabolism 2002;87(12):5618-24.
2002: Schmidt Ida Maria; Chellakooty Marla; Haavisto Anne-Maarit; Boisen Kirsten Arntz; Damgaard Ida Norgil; Steendahl Ulla; Toppari Jorma; Skakkebaek Niels Erik; Main Katharina Maria
Gender difference in breast tissue size in infancy: correlation with serum estradiol.
Pediatric research 2002;52(5):682-6.
2002: Rajpert-De Meyts Ewa; Leffers Henrik; Daugaard Gedske; Andersen Charlotte B; Petersen Peter M; Hinrichsen Jane; Pedersen Lene G; Skakkebaek Niels E
Analysis of the polymorphic CAG repeat length in the androgen receptor gene in patients with testicular germ cell cancer.
International journal of cancer. Journal international du cancer 2002;102(2):201-4.
2002: Juul Anders; Skakkebaek Niels E
[Testosterone treatment of elderly men. The so called andropause doesn't exist]
Ugeskrift for laeger 2002;164(42):4941-2.
2002: Skakkebaek N E
Carcinoma in situ of the testis: frequency and relationship to invasive germ cell tumours in infertile men. N. E. Skakkebaek. Histopathology 1978; 2; 157-170.
Histopathology 2002;41(3A):2-3; discussion 3-4.
2002: Juul Anders; Skakkebaek Niels E
Androgens and the ageing male.
Human reproduction update 2002;8(5):423-33.
2002: Almstrup Kristian; Fernández Mariana F; Petersen Jørgen H; Olea Nicolas; Skakkebaek Niels E; Leffers Henrik
Dual effects of phytoestrogens result in u-shaped dose-response curves.
Environmental health perspectives 2002;110(8):743-8.
2002: Jørgensen Niels; Carlsen Elisabeth; Nermoen Ingrid; Punab Margus; Suominen Jyrki; Andersen Anne-Grethe; Andersson Anna-Maria; Haugen Trine B; Horte Antero; Jensen Tina Kold; Magnus Øystein; Petersen Jørgen Holm; Vierula Matti; Toppari Jorma; Skakkebaek Niels E
East-West gradient in semen quality in the Nordic-Baltic area: a study of men from the general population in Denmark, Norway, Estonia and Finland.
Human reproduction (Oxford, England) 2002;17(8):2199-208.
2002: Gravholt Claus Højbjerg; Naeraa Rune Weis; Andersson Anna-Maria; Christiansen Jens Sandahl; Skakkebaek Niels Erik
Inhibin A and B in adolescents and young adults with Turner's syndrome and no sign of spontaneous puberty.
Human reproduction (Oxford, England) 2002;17(8):2049-53.
2002: Punab Margus; Zilaitiene Birute; Jørgensen Niels; Horte Antero; Matulevicius Valentinas; Peetsalu Ants; Skakkebaek Niels E
Regional differences in semen qualities in the Baltic region.
International journal of andrology 2002;25(4):243-52.
2002: Lajer Henrik; Daugaard Gedske; Andersson Anna-Maria; Skakkebaek Niels Erik
Clinical use of serum TRA-1-60 as tumor marker in patients with germ cell cancer.
International journal of cancer. Journal international du cancer 2002;100(2):244-6.
2002: Christiansen P; Andersson A-M; Skakkebaek N E; Juul A
Serum inhibin B, FSH, LH and testosterone levels before and after human chorionic gonadotropin stimulation in prepubertal boys with cryptorchidism.
European journal of endocrinology / European Federation of Endocrine Societies 2002;147(1):95-101.
2002: Lange Martin; Svendsen Ole L; Skakkebaek Niels E; Müller Jørn; Juul Anders; Schmiegelow Marianne; Feldt-Rasmussen Ulla
An audit of the insulin-tolerance test in 255 patients with pituitary disease.
European journal of endocrinology / European Federation of Endocrine Societies 2002;147(1):41-7.
2002: Norgil Damgaard Ida; Main Katharina Maria; Toppari Jorma; Skakkebaek Niels E
Impact of exposure to endocrine disrupters in utero and in childhood on adult reproduction.
Best practice & research. Clinical endocrinology & metabolism 2002;16(2):289-309.
2002: Chellakooty Marla; Skibsted Lillian; Skouby Sven O; Andersson Anna-Maria; Petersen Jørgen H; Main Katharina M; Skakkebaek Niels E; Juul Anders
Longitudinal study of serum placental GH in 455 normal pregnancies: correlation to gestational age, fetal gender, and weight.
The Journal of clinical endocrinology and metabolism 2002;87(6):2734-9.
2002: Jensen Tina Kold; Carlsen Elisabeth; Jørgensen Niels; Berthelsen Jørgen G; Keiding Niels; Christensen Kaare; Petersen Jørgen Holm; Knudsen Lisbeth B; Skakkebaek Niels E
Poor semen quality may contribute to recent decline in fertility rates.
Human reproduction (Oxford, England) 2002;17(6):1437-40.
2002: Teilmann Grete; Juul Anders; Skakkebaek Niels E; Toppari Jorma
Putative effects of endocrine disrupters on pubertal development in the human.
Best practice & research. Clinical endocrinology & metabolism 2002;16(1):105-21.
2002: Mol Nanette M; Sørensen Nicolina; Weihe Pal; Andersson Anna-Maria; Jørgensen Niels; Skakkebaek Niels E; Keiding Niels; Grandjean Philippe
Spermaturia and serum hormone concentrations at the age of puberty in boys prenatally exposed to polychlorinated biphenyls.
European journal of endocrinology / European Federation of Endocrine Societies 2002;146(3):357-63.
2002: Slama R; Eustache F; Ducot B; Jensen T K; Jørgensen N; Horte A; Irvine S; Suominen J; Andersen A G; Auger J; Vierula M; Toppari J; Andersen A N; Keiding N; Skakkebaek N E; Spira A; Jouannet P
Time to pregnancy and semen parameters: a cross-sectional study among fertile couples from four European cities.
Human reproduction (Oxford, England) 2002;17(2):503-15.
2002: Rajpert-De Meyts Ewa; Leffers Henrik; Petersen Jørgen H; Andersen Anne Grethe; Carlsen Elisabeth; Jørgensen Niels; Skakkebaek Niels E
CAG repeat length in androgen-receptor gene and reproductive variables in fertile and infertile men.
Lancet 2002;359(9300):44-6.
2002: Andersen A G; Ziebe S; Jørgensen N; Petersen J H; Skakkebaek N E; Andersen A Nyboe
Time to pregnancy in relation to semen quality assessed by CASA before and after sperm separation.
Human reproduction (Oxford, England) 2002;17(1):173-7.
2002: Main Katharina M; Schmidt Ida M; Toppari Jorma; Skakkebaek Niels E
Early postnatal treatment of hypogonadotropic hypogonadism with recombinant human FSH and LH.
European journal of endocrinology / European Federation of Endocrine Societies 2002;146(1):75-9.
2002: Skakkebaek Niels E
Endocrine disrupters and testicular dysgenesis syndrome.
Hormone research 2002;57 Suppl 2():43.
2002: Christiansen Peter; Skakkebaek Niels E
Pulsatile gonadotropin-releasing hormone treatment of men with idiopathic hypogonadotropic hypogonadism.
Hormone research 2002;57(1-2):32-6.
2001: Sneppen S B; Lange M; Pedersen L M; Kristensen L L Ø; Main K M; Juul A; Skakkebaek N E; Feldt-Rasmussen U
Total and free insulin-like growth factor I, insulin-like growth factor binding protein 3 and acid-labile subunit reflect clinical activity in acromegaly.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2001;11(6):384-91.
2001: Boisen K A; Main K M; Rajpert-De Meyts E; Skakkebaek N E
Are male reproductive disorders a common entity? The testicular dysgenesis syndrome.
Annals of the New York Academy of Sciences 2001;948():90-9.
2001: Auger J; Eustache F; Andersen A G; Irvine D S; Jørgensen N; Skakkebaek N E; Suominen J; Toppari J; Vierula M; Jouannet P
Sperm morphological defects related to environment, lifestyle and medical history of 1001 male partners of pregnant women from four European cities.
Human reproduction (Oxford, England) 2001;16(12):2710-7.
2001: Jensen T K; Slama R; Ducot B; Suominen J; Cawood E H; Andersen A G; Eustache F; Irvine S; Auger S; Jouannet P; Vierula M; Jørgensen N; Toppari J; Skakkebaek N E; Keiding N; Spira A
Regional differences in waiting time to pregnancy among fertile couples from four European cities.
Human reproduction (Oxford, England) 2001;16(12):2697-704.
2001: Bartkova J; Falck J; Rajpert-De Meyts E; Skakkebaek N E; Lukas J; Bartek J
Chk2 tumour suppressor protein in human spermatogenesis and testicular germ-cell tumours.
Oncogene 2001;20(41):5897-902.
2001: Krausz C; Quintana-Murci L; Rajpert-De Meyts E; Jørgensen N; Jobling M A; Rosser Z H; Skakkebaek N E; McElreavey K
Identification of a Y chromosome haplogroup associated with reduced sperm counts.
Human molecular genetics 2001;10(18):1873-7.
2001: Gyllenborg J; Rasmussen S L; Borch-Johnsen K; Heitmann B L; Skakkebaek N E; Juul A
Cardiovascular risk factors in men: The role of gonadal steroids and sex hormone-binding globulin.
Metabolism: clinical and experimental 2001;50(8):882-8.
2001: Lange M; Thulesen J; Feldt-Rasmussen U; Skakkebaek N E; Vahl N; Jørgensen J O; Christiansen J S; Poulsen S S; Sneppen S B; Juul A
Skin morphological changes in growth hormone deficiency and acromegaly.
European journal of endocrinology / European Federation of Endocrine Societies 2001;145(2):147-53.
2001: Andersson A M; Skakkebaek N E
Serum inhibin B levels during male childhood and puberty.
Molecular and cellular endocrinology 2001;180(1-2):103-7.
2001: Krausz C; Rajpert-De Meyts E; Frydelund-Larsen L; Quintana-Murci L; McElreavey K; Skakkebaek N E
Double-blind Y chromosome microdeletion analysis in men with known sperm parameters and reproductive hormone profiles: microdeletions are specific for spermatogenic failure.
The Journal of clinical endocrinology and metabolism 2001;86(6):2638-42.
2001: Schmiegelow M; Lassen S; Poulsen H S; Schmiegelow K; Hertz H; Andersson A M; Skakkebaek N E; Müller J
Gonadal status in male survivors following childhood brain tumors.
The Journal of clinical endocrinology and metabolism 2001;86(6):2446-52.
2001: Leffers H; Naesby M; Vendelbo B; Skakkebaek N E; Jørgensen M
Oestrogenic potencies of Zeranol, oestradiol, diethylstilboestrol, Bisphenol-A and genistein: implications for exposure assessment of potential endocrine disrupters.
Human reproduction (Oxford, England) 2001;16(5):1037-45.
2001: Jørgensen N; Andersen A G; Eustache F; Irvine D S; Suominen J; Petersen J H; Andersen A N; Auger J; Cawood E H; Horte A; Jensen T K; Jouannet P; Keiding N; Vierula M; Toppari J; Skakkebaek N E
Regional differences in semen quality in Europe.
Human reproduction (Oxford, England) 2001;16(5):1012-9.
2001: Skakkebaek N E; Rajpert-De Meyts E; Main K M
Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects.
Human reproduction (Oxford, England) 2001;16(5):972-8.
2001: Mikkelsen A L; Andersson A M; Skakkebaek N E; Lindenberg S
Basal concentrations of oestradiol may predict the outcome of in-vitro maturation in regularly menstruating women.
Human reproduction (Oxford, England) 2001;16(5):862-7.
2001: Fisker S; Nørrelund H; Juul A; Skakkebaek N E; Christiansen J S; Jørgensen J O
The growth hormone (GH)-insulin-like growth factor axis during testosterone replacement therapy in GH-treated hypopituitary males.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2001;11(2):104-9.
2001: Virtanen H E; Kaleva M; Haavisto A M; Schmidt I M; Chellakooty M; Main K M; Skakkebaek N E; Toppari J
The birth rate of hypospadias in the Turku area in Finland.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2001;109(2):96-100.
2001: Ishøy T; Andersson A M; Suadicani P; Guldager B; Appleyard M; Gyntelberg F; Skakkebaek N E;
Major reproductive health characteristics in male Gulf War Veterans. The Danish Gulf War Study.
Danish medical bulletin 2001;48(1):29-32.
2001: Quintana-Murci L; Krausz C; Heyer E; Gromoll J; Seifer I; Barton D E; Barrett T; Skakkebaek N E; Rajpert-De Meyts E; Mitchell M; Lee A C; Jobling M A; McElreavey K
The relationship between Y chromosome DNA haplotypes and Y chromosome deletions leading to male infertility.
Human genetics 2001;108(1):55-8.
2001: Holm M; Lenz S; De Meyts E R; Skakkebaek N E
Microcalcifications and carcinoma in situ of the testis.
BJU international 2001;87(2):144-9.
2001: Kaleva M; Virtanen H; Haavisto A M; Main K; Skakkebaek N E; Toppari J
Incidence of cryptorchidism in Finnish boys.
Hormone research 2001;55(1):54.
2000: Kledal T J; Rajpert-De Meyts E; Skakkebaek N E; Jørgensen K D
A dose-finding study of in utero and lactational exposure to diethylstilboestrol and flutamide in 129/Sv mice.
Pharmacology & toxicology 2000;87(6):255-7.
2000: Main K M; Schmidt I M; Skakkebaek N E
A possible role for reproductive hormones in newborn boys: progressive hypogonadism without the postnatal testosterone peak.
The Journal of clinical endocrinology and metabolism 2000;85(12):4905-7.
2000: Sneppen S B; Main K M; Juul A; Pedersen L M; Kristensen L O; Skakkebaek N E; Feldt-Rasmussen U
Sweat secretion rates in growth hormone disorders.
Clinical endocrinology 2000;53(5):601-8.
2000: Jacobsen R; Bostofte E; Skakkebaek N E; Hansen J; Moller H
Offspring sex ratio of subfertile men and men with abnormal sperm characteristics.
Human reproduction (Oxford, England) 2000;15(11):2369-70.
2000: Kledal T J; Jorgensen M; Mengarda F; Skakkebaek N E; Leffers H
New methods for detection of potential endocrine disruptors.
Andrologia 2000;32(4-5):271-8.
2000: Jacobsen R; Bostofte E; Engholm G; Hansen J; Olsen J H; Skakkebaek N E; Moller H
Risk of testicular cancer in men with abnormal semen characteristics: cohort study.
BMJ (Clinical research ed.) 2000;321(7264):789-92.
2000: Jacobsen R; Bostofte E; Engholm G; Hansen J; Skakkebaek N E; Møller H
Fertility and offspring sex ratio of men who develop testicular cancer: a record linkage study.
Human reproduction (Oxford, England) 2000;15(9):1958-61.
2000: Bartkova J; Thullberg M; Rajpert-De Meyts E; Skakkebaek N E; Bartek J
Lack of p19INK4d in human testicular germ-cell tumours contrasts with high expression during normal spermatogenesis.
Oncogene 2000;19(36):4146-50.
2000: Müller J; Juul A; Andersson A M; Sehested A; Skakkebaek N E
Hormonal changes during GnRH analogue therapy in children with central precocious puberty.
Journal of pediatric endocrinology & metabolism : JPEM 2000;13 Suppl 1():739-46.
2000: Larsen L; Scheike T; Jensen T K; Bonde J P; Ernst E; Hjollund N H; Zhou Y; Skakkebaek N E; Giwercman A
Computer-assisted semen analysis parameters as predictors for fertility of men from the general population. The Danish First Pregnancy Planner Study Team.
Human reproduction (Oxford, England) 2000;15(7):1562-7.
2000: Giwercman A; Kledal T; Schwartz M; Giwercman Y L; Leffers H; Zazzi H; Wedell A; Skakkebaek N E
Preserved male fertility despite decreased androgen sensitivity caused by a mutation in the ligand-binding domain of the androgen receptor gene.
The Journal of clinical endocrinology and metabolism 2000;85(6):2253-9.
2000: Nørrelund H; Vahl N; Juul A; Møller N; Alberti K G; Skakkebaek N E; Christiansen J S; Jørgensen J O
Continuation of growth hormone (GH) therapy in GH-deficient patients during transition from childhood to adulthood: impact on insulin sensitivity and substrate metabolism.
The Journal of clinical endocrinology and metabolism 2000;85(5):1912-7.
2000: Vahl N; Juul A; Jørgensen J O; Orskov H; Skakkebaek N E; Christiansen J S
Continuation of growth hormone (GH) replacement in GH-deficient patients during transition from childhood to adulthood: a two-year placebo-controlled study.
The Journal of clinical endocrinology and metabolism 2000;85(5):1874-81.
2000: Jørgensen M; Vendelbo B; Skakkebaek N E; Leffers H
Assaying estrogenicity by quantitating the expression levels of endogenous estrogen-regulated genes.
Environmental health perspectives 2000;108(5):403-12.
2000: Sehested A; Juul A A; Andersson A M; Petersen J H; Jensen T K; Müller J; Skakkebaek N E
Serum inhibin A and inhibin B in healthy prepubertal, pubertal, and adolescent girls and adult women: relation to age, stage of puberty, menstrual cycle, follicle-stimulating hormone, luteinizing hormone, and estradiol levels.
The Journal of clinical endocrinology and metabolism 2000;85(4):1634-40.
2000: Giwercman A; Hansen L L; Skakkebaek N E
Initiation of sperm production after bilateral orchiopexy: clinical and biological implications.
The Journal of urology 2000;163(4):1255-6.
2000: Juul A; Fisker S; Scheike T; Hertel T; Müller J; Orskov H; Skakkebaek N E
Serum levels of growth hormone binding protein in children with normal and precocious puberty: relation to age, gender, body composition and gonadal steroids.
Clinical endocrinology 2000;52(2):165-72.
2000: Andersen A G; Jensen T K; Carlsen E; Jørgensen N; Andersson A M; Krarup T; Keiding N; Skakkebaek N E
High frequency of sub-optimal semen quality in an unselected population of young men.
Human reproduction (Oxford, England) 2000;15(2):366-72.
2000: Bartkova J; Thullberg M; Rajpert-De Meyts E; Skakkebaek N E; Bartek J
Cell cycle regulators in testicular cancer: loss of p18INK4C marks progression from carcinoma in situ to invasive germ cell tumours.
International journal of cancer. Journal international du cancer 2000;85(3):370-5.
2000: Jensen T K; Vierula M; Hjollund N H; Saaranen M; Scheike T; Saarikoski S; Suominen J; Keiski A; Toppari J; Skakkebaek N E
Semen quality among Danish and Finnish men attempting to conceive. The Danish First Pregnancy Planner Study Team.
European journal of endocrinology / European Federation of Endocrine Societies 2000;142(1):47-52.
2000: Sehested A; Andersson A M; Müller J; Skakkebaek N E
Serum inhibin A and inhibin B in central precocious puberty before and during treatment with GnRH agonists.
Hormone research 2000;54(2):84-91.
1999: Juul A; Bernasconi S; Chatelain P; Hindmarsh P; Hochberg Z; Hokken-Koelega A; de Muinck Keizer-Schrama S M; Kiess W; Oberfield S; Parks J; Strasburger C J; Volta C; Westphal O; Skakkebaek N E
Diagnosis of growth hormone (GH) deficiency and the use of GH in children with growth disorders.
Hormone research 1999;51(6):284-99.
1999: Møller H; Skakkebaek N E
[Occurrence of testicular cancer in subfertile men. A case-control study]
Ugeskrift for laeger 1999;161(47):6490-2.
1999: Rajpert-De Meyts E; Jørgensen N; Graem N; Müller J; Cate R L; Skakkebaek N E
Expression of anti-Müllerian hormone during normal and pathological gonadal development: association with differentiation of Sertoli and granulosa cells.
The Journal of clinical endocrinology and metabolism 1999;84(10):3836-44.
1999: Andersson A M; Skakkebaek N E
Exposure to exogenous estrogens in food: possible impact on human development and health.
European journal of endocrinology / European Federation of Endocrine Societies 1999;140(6):477-85.
1999: Carlsen E; Olsson C; Petersen J H; Andersson A M; Skakkebaek N E
Diurnal rhythm in serum levels of inhibin B in normal men: relation to testicular steroids and gonadotropins.
The Journal of clinical endocrinology and metabolism 1999;84(5):1664-9.
1999: Weidner I S; Møller H; Jensen T K; Skakkebaek N E
Risk factors for cryptorchidism and hypospadias.
The Journal of urology 1999;161(5):1606-9.
1999: Bartkova J; Rajpert-de Meyts E; Skakkebaek N E; Bartek J
D-type cyclins in adult human testis and testicular cancer: relation to cell type, proliferation, differentiation, and malignancy.
The Journal of pathology 1999;187(5):573-81.
1999: Laursen E M; Lanng S; Rasmussen M H; Koch C; Skakkebaek N E; Müller J
Normal spontaneous and stimulated GH levels despite decreased IGF-I concentrations in cystic fibrosis patients.
European journal of endocrinology / European Federation of Endocrine Societies 1999;140(4):315-21.
1999: Petersen P M; Skakkebaek N E; Vistisen K; Rørth M; Giwercman A
Semen quality and reproductive hormones before orchiectomy in men with testicular cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(3):941-7.
1999: Petersen P M; Skakkebaek N E; Rørth M; Giwercman A
Semen quality and reproductive hormones before and after orchiectomy in men with testicular cancer.
The Journal of urology 1999;161(3):822-6.
1999: Gyllenborg J; Skakkebaek N E; Nielsen N C; Keiding N; Giwercman A
Secular and seasonal changes in semen quality among young Danish men: a statistical analysis of semen samples from 1927 donor candidates during 1977-1995.
International journal of andrology 1999;22(1):28-36.
1999: Møller H; Skakkebaek N E
Risk of testicular cancer in subfertile men: case-control study.
BMJ (Clinical research ed.) 1999;318(7183):559-62.
1999: Petersen P M; Giwercman A; Hansen S W; Berthelsen J G; Daugaard G; Rørth M; Skakkebaek N E
Impaired testicular function in patients with carcinoma-in-situ of the testis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(1):173-9.
1999: Petersen P M; Andersson A M; Rørth M; Daugaard G; Skakkebaek N E
Undetectable inhibin B serum levels in men after testicular irradiation.
The Journal of clinical endocrinology and metabolism 1999;84(1):213-5.
1999: Müller J; Ritzén E M; Ivarsson S A; Rajpert-De Meyts E; Norjavaara E; Skakkebaek N E
Management of males with 45,X/46,XY gonadal dysgenesis.
Hormone research 1999;52(1):11-4.
1999: Jørgensen J O; Ovesen P; Juul A; Hansen T K; Skakkebaek N E; Christiansen J S
Impact of growth hormone administration on other hormonal axes.
Hormone research 1999;51 Suppl 3():121-6.
1999: Müller J; Skakkebaek N E; Jacobsen B B; Keller E; Heinrich U; Hartmann K; Hokken-Koelega A C; Delemarre van de Waal H A
Norditropin SimpleXx: a liquid human growth hormone formulation, a pen system and an auto-insertion device.
Hormone research 1999;51 Suppl 3():109-12.
1998: Andersson A M; Müller J; Skakkebaek N E
Different roles of prepubertal and postpubertal germ cells and Sertoli cells in the regulation of serum inhibin B levels.
The Journal of clinical endocrinology and metabolism 1998;83(12):4451-8.
1998: Juul A; Møller S; Mosfeldt-Laursen E; Rasmussen M H; Scheike T; Pedersen S A; Kastrup K W; Yu H; Mistry J; Rasmussen S; Müller J; Henriksen J; Skakkebaek N E
The acid-labile subunit of human ternary insulin-like growth factor binding protein complex in serum: hepatosplanchnic release, diurnal variation, circulating concentrations in healthy subjects, and diagnostic use in patients with growth hormone deficiency.
The Journal of clinical endocrinology and metabolism 1998;83(12):4408-15.
1998: Weidner I S; Møller H; Jensen T K; Skakkebaek N E
Cryptorchidism and hypospadias in sons of gardeners and farmers.
Environmental health perspectives 1998;106(12):793-6.
1998: Jensen T K; Henriksen T B; Hjollund N H; Scheike T; Kolstad H; Giwercman A; Ernst E; Bonde J P; Skakkebaek N E; Olsen J
Adult and prenatal exposures to tobacco smoke as risk indicators of fertility among 430 Danish couples.
American journal of epidemiology 1998;148(10):992-7.
1998: Jensen T K; Hjollund N H; Henriksen T B; Scheike T; Kolstad H; Giwercman A; Ernst E; Bonde J P; Skakkebaek N E; Olsen J
Does moderate alcohol consumption affect fertility? Follow up study among couples planning first pregnancy.
BMJ (Clinical research ed.) 1998;317(7157):505-10.
1998: Jensen T K; Henriksen T B; Hjollund N H; Scheike T; Kolstad H; Giwercman A; Ernst E; Bonde J P; Skakkebaek N E; Olsen J
Caffeine intake and fecundability: a follow-up study among 430 Danish couples planning their first pregnancy.
Reproductive toxicology (Elmsford, N.Y.) 1998;12(3):289-95.
1998: Toppari J; Skakkebaek N E
Sexual differentiation and environmental endocrine disrupters.
Baillière's clinical endocrinology and metabolism 1998;12(1):143-56.
1998: Petersen P M; Giwercman A; Skakkebaek N E; Rørth M
Gonadal function in men with testicular cancer.
Seminars in oncology 1998;25(2):224-33.
1998: Juul A; Vahl N; Jørgensen J O; Christiansen J S; Sneppen S B; Feldt-Rasmussen U; Skakkebaek N E
Consequences of stopping growth hormone (GH) therapy in young GH deficient patients with childhood onset disease.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 1998;8 Suppl A():15-9.
1998: Andersson A M; Toppari J; Haavisto A M; Petersen J H; Simell T; Simell O; Skakkebaek N E
Longitudinal reproductive hormone profiles in infants: peak of inhibin B levels in infant boys exceeds levels in adult men.
The Journal of clinical endocrinology and metabolism 1998;83(2):675-81.
1998: Jørgensen M; Hummel R; Bévort M; Andersson A M; Skakkebaek N E; Leffers H
Detection of oestrogenic chemicals by assaying the expression level of oestrogen regulated genes.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1998;106(1):245-51.
1998: Rajpert-De Meyts E; Jørgensen N; Brøndum-Nielsen K; Müller J; Skakkebaek N E
Developmental arrest of germ cells in the pathogenesis of germ cell neoplasia.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1998;106(1):198-204; discussion 204-6.
1998: Petersen P M; Skakkebaek N E; Giwercman A
Gonadal function in men with testicular cancer: biological and clinical aspects.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1998;106(1):24-34; discussion 34-6.
1998: Skakkebaek N E; Rajpert-De Meyts E; Jørgensen N; Carlsen E; Petersen P M; Giwercman A; Andersen A G; Jensen T K; Andersson A M; Müller J
Germ cell cancer and disorders of spermatogenesis: an environmental connection?
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1998;106(1):3-11; discussion 12.
1998: Skakkebaek N E
Trends in male reproductive health. Environmental aspects.
Advances in experimental medicine and biology 1998;444():1-2; discussion 3-4.
1998: Juul A; Andersson A M; Pedersen S A; Jørgensen J O; Christiansen J S; Groome N P; Skakkebaek N E
Effects of growth hormone replacement therapy on IGF-related parameters and on the pituitary-gonadal axis in GH-deficient males. A double-blind, placebo-controlled crossover study.
Hormone research 1998;49(6):269-78.
1998: Rasmussen A K; Feldt-Rasmussen U; Skakkebaek N E; Jørgensen J O; Christiansen J S; Müller J
Autoimmune thyrotoxicosis developed during growth hormone (GH) treatment of an adult with childhood onset GH-deficiency. A causal relationship?
Autoimmunity 1998;27(1):57-61.
1997: Ottesen A M; Kirchhoff M; De-Meyts E R; Maahr J; Gerdes T; Rose H; Lundsteen C; Petersen P M; Philip J; Skakkebaek N E
Detection of chromosomal aberrations in seminomatous germ cell tumours using comparative genomic hybridization.
Genes, chromosomes & cancer 1997;20(4):412-8.
1997: Jensen T K; Andersson A M; Hjollund N H; Scheike T; Kolstad H; Giwercman A; Henriksen T B; Ernst E; Bonde J P; Olsen J; McNeilly A; Groome N P; Skakkebaek N E
Inhibin B as a serum marker of spermatogenesis: correlation to differences in sperm concentration and follicle-stimulating hormone levels. A study of 349 Danish men.
The Journal of clinical endocrinology and metabolism 1997;82(12):4059-63.
1997: Andersson A M; Juul A; Petersen J H; Müller J; Groome N P; Skakkebaek N E
Serum inhibin B in healthy pubertal and adolescent boys: relation to age, stage of puberty, and follicle-stimulating hormone, luteinizing hormone, testosterone, and estradiol levels.
The Journal of clinical endocrinology and metabolism 1997;82(12):3976-81.
1997: Møller H; Skakkebaek N E
Testicular cancer and cryptorchidism in relation to prenatal factors: case-control studies in Denmark.
Cancer causes & control : CCC 1997;8(6):904-12.
1997: Juul A; Scheike T; Pedersen A T; Main K M; Andersson A M; Pedersen L M; Skakkebaek N E
Changes in serum concentrations of growth hormone, insulin, insulin-like growth factor and insulin-like growth factor-binding proteins 1 and 3 and urinary growth hormone excretion during the menstrual cycle.
Human reproduction (Oxford, England) 1997;12(10):2123-8.
1997: Giwercman A; Thomsen J K; Hertz J; Berthelsen J G; Jensen V; Meinecke B; Thormann L; Storm H H; Skakkebaek N E
Prevalence of carcinoma in situ of the testis in 207 oligozoospermic men from infertile couples: prospective study of testicular biopsies.
BMJ (Clinical research ed.) 1997;315(7114):989-91.
1997: Juul A; Holm K; Kastrup K W; Pedersen S A; Michaelsen K F; Scheike T; Rasmussen S; Müller J; Skakkebaek N E
Free insulin-like growth factor I serum levels in 1430 healthy children and adults, and its diagnostic value in patients suspected of growth hormone deficiency.
The Journal of clinical endocrinology and metabolism 1997;82(8):2497-502.
1997: Petersen P M; Lenz S C; Giwercman A J; Sommer P; Skakkebaek N E
[Testicular carcinoma in situ detected by ultrasound in infertile men]
Ugeskrift for laeger 1997;159(25):3962-3.
1997: Juul A; Müller J; Skakkebaek N E
Prostate specific antigen in boys with precocious puberty before and during gonadal suppression by GnRH agonist treatment.
European journal of endocrinology / European Federation of Endocrine Societies 1997;136(4):401-5.
1997: Juul A; Kastrup K W; Pedersen S A; Skakkebaek N E
Growth hormone (GH) provocative retesting of 108 young adults with childhood-onset GH deficiency and the diagnostic value of insulin-like growth factor I (IGF-I) and IGF-binding protein-3.
The Journal of clinical endocrinology and metabolism 1997;82(4):1195-201.
1997: Jørgensen N; Müller J; Jaubert F; Clausen O P; Skakkebaek N E
Heterogeneity of gonadoblastoma germ cells: similarities with immature germ cells, spermatogonia and testicular carcinoma in situ cells.
Histopathology 1997;30(2):177-86.
1997: Juul A; Skakkebaek N E
Prediction of the outcome of growth hormone provocative testing in short children by measurement of serum levels of insulin-like growth factor I and insulin-like growth factor binding protein 3.
The Journal of pediatrics 1997;130(2):197-204.

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Niels Skakkebaek

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