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Stefanie Bode-Böger

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Gernot Beutel; Stefanie M Bode-Böger; Jan T Kielstein; Jens Martens-Lobenhoffer; Ronny Perthel; Mayuren Suntharalingam; Heike Kielstein
Effect of chronic elevated asymmetric dimethylarginine (ADMA) levels on granulopoiesis.
Anja Kittel; Jörg König; Renke Maas; Jens Martens-Lobenhoffer; Maren Mieth; Stefanie M Bode-Böger; Bernd Hohenstein; Natalia Jarzebska; Norbert Weiss; Roman N Rodionov
In vivo evidence that Agxt2 can regulate plasma levels of dimethylarginines in mice.
Jens Martens-Lobenhoffer; Roman N Rodionov; Stefanie M Bode-Böger
Probing AGXT2 enzyme activity in mouse tissue by applying stable isotope-labeled asymmetric dimethyl arginine as substrate.

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2013: Gernot Beutel; Stefanie M Bode-Böger; Jan T Kielstein; Jens Martens-Lobenhoffer; Ronny Perthel; Mayuren Suntharalingam; Heike Kielstein
Effect of chronic elevated asymmetric dimethylarginine (ADMA) levels on granulopoiesis.
Annals of hematology 2013;92(4):505-8.
2013: Anja Kittel; Jörg König; Renke Maas; Jens Martens-Lobenhoffer; Maren Mieth; Stefanie M Bode-Böger; Bernd Hohenstein; Natalia Jarzebska; Norbert Weiss; Roman N Rodionov
In vivo evidence that Agxt2 can regulate plasma levels of dimethylarginines in mice.
Biochemical and biophysical research communications 2013;430(1):84-9.
2012: Jens Martens-Lobenhoffer; Roman N Rodionov; Stefanie M Bode-Böger
Probing AGXT2 enzyme activity in mouse tissue by applying stable isotope-labeled asymmetric dimethyl arginine as substrate.
Journal of mass spectrometry : JMS 2012;47(12):1594-600.
2012: Uwe Tröger; Rüdiger C Braun-Dullaeus; Andreas Drust; Jens Martens-Lobenhoffer; Ivan Tanev; Stefanie M Bode-Böger
Decreased meropenem levels in Intensive Care Unit patients with augmented renal clearance: benefit of therapeutic drug monitoring.
International journal of antimicrobial agents 2012;40(4):370-2.
2012: Jens Martens-Lobenhoffer; Stefanie M Bode-Böger
Quantification of L-arginine, asymmetric dimethylarginine and symmetric dimethylarginine in human plasma: a step improvement in precision by stable isotope dilution mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2012;904():140-3.
2012: Gabriella Vida; Tibor Ertl; Jens Martens-Lobenhoffer; Endre Sulyok; Stefanie M Bode-Böger
Birth by cesarean section is associated with elevated neonatal plasma levels of dimethylarginines.
Pediatrics international : official journal of the Japan Pediatric Society 2012;54(4):476-9.
2012: Alicja Bukowska; Stefanie M Bode-Böger; Uwe Lendeckel; Andreas Goette
Physiologic and pathophysiologic role of calpain: implications for the occurrence of atrial fibrillation.
Cardiovascular therapeutics 2012;30(3):e115-27.
2012: Andreas Drust; Raimund Firsching; Michael Luchtmann; Jens Martens-Lobenhoffer; Uwe Tröger; Stefanie M Bode-Böger
Recurrent seizures in a levetiracetam-treated patient after subarachnoid hemorrhage: a matter of enhanced renal function?
Epilepsy & behavior : E&B 2012;23(3):394-5.
2012: Jan T Kielstein; Jens Martens-Lobenhoffer; Stefanie M Bode-Böger; Kristin Jäger; Ronny Perthel; Song Rong; Mayuren Suntharalingam; Heike Nave
Asymmetric dimethylarginine may mediate increased heat pain threshold in experimental chronic kidney disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012;27(3):899-902.
2012: Alessandra D'Alessandro; Matthias Hammwöhner; Uwe Lendeckel; Jens Martens-Lobenhoffer; Senad Medunjanin; Ursula Ravens; Fortunato Scalera; Soenke Weinert; Alicja Bukowska; Dobromir Dobrev; Stefanie M Bode-Böger
The impact of rapid atrial pacing on ADMA and endothelial NOS.
International journal of cardiology 2012;154(2):141-6.
2012: Jan-Sören Padberg; Matijs Van Meurs; Jan G Zijlstra; Jens Martens-Lobenhoffer; Stefanie M Bode-Böger; Jan T Kielstein; Csaba P Kovesdy; Philipp Kümpers
Indoleamine-2,3-dioxygenase activity in experimental human endotoxemia.
Experimental & translational stroke medicine 2012;4(1):24.
2012: Aleksandra Jaźwińska-Kozuba; Olga Kruszelnicka; Jens Martens-Lobenhoffer; Jarosław Rycaj; Andrzej Surdacki; Urszula Godula-Stuglik; Stefanie M Bode-Böger
Associations between Endogenous Dimethylarginines and Renal Function in Healthy Children and Adolescents.
International journal of molecular sciences 2012;13(11):15464-74.
2012: Shufen Chen; Milani Deb; Qiang Dong; Annemarie Goldbecker; Jan T Kielstein; Na Li; Ralf Lichtinghagen; Jens Martens-Lobenhoffer; Anita B Tryc; Karin Weissenborn; Stefanie M Bode-Böger; Hans Worthmann
Association of dimethylarginines and mediators of inflammation after acute ischemic stroke.
Journal of neuroinflammation 2012;9():251.
2012: Oktay Tutarel; Mechthild Westhoff-Bleck; Svjetlana Lovric; Jens Martens-Lobenhoffer; Bernhard Schieffer; Johann Bauersachs; Stefanie M Bode-Böger; Agnieszka Denecke; Jan T Kielstein
Asymmetrical dimethylarginine--more sensitive than NT-proBNP to diagnose heart failure in adults with congenital heart disease.
PloS one 2012;7(3):e33795.
2012: Nadja Scherbakov; Gulistan Turhan; Stephan von Haehling; Stefanie M Bode-Böger; Martin Ebinger; Matthias Endres; Thomas Kung; Thomas Liman; Jens Martens-Lobenhoffer; Anja Sandek; Wolfram Doehner
Endothelial dysfunction of the peripheral vascular bed in the acute phase after ischemic stroke.
Cerebrovascular diseases (Basel, Switzerland) 2012;33(1):37-46.
2011: Jens Martens-Lobenhoffer; Roman N Rodionov; Andreas Drust; Stefanie M Bode-Böger
Detection and quantification of α-keto-δ-(N(G),N(G)-dimethylguanidino)valeric acid: a metabolite of asymmetric dimethylarginine.
Analytical biochemistry 2011;419(2):234-40.
2011: Jan T Kielstein; Volker Kliem; Ralf Lichtinghagen; Svjetlana Lovric; Jens Martens-Lobenhoffer; Ronny Perthel; Hendrik Veldink; Hermann Haller; Stefanie M Bode-Böger
Unilateral nephrectomy causes an abrupt increase in inflammatory mediators and a simultaneous decrease in plasma ADMA: a study in living kidney donors.
American journal of physiology. Renal physiology 2011;301(5):F1042-6.
2011: Helge Immo Lehmann; Jens Martens-Lobenhoffer; Friedrich-Wilhelm Röhl; Alicja Bukowska; Ali Ghanem; Alessandra D'Alessandro; Matthias Hammwöhner; Helmut U Klein; Stefanie M Bode-Böger
Asymmetric dimethylarginine predicts appropriate implantable cardioverter-defibrillator intervention in patients with left ventricular dysfunction.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2011;13(10):1428-35.
2011: Jens Martens-Lobenhoffer; Victoria Rupprecht; Stefanie M Bode-Böger
Determination of micafungin and anidulafungin in human plasma: UV- or mass spectrometric quantification?
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2011;879(22):2051-6.
2011: Attila Cziráki; Zénó Ajtay; Zsófia Lenkey; Endre Sulyok; Sándor Szabados; Nasri Alotti; Jens Martens-Lobenhoffer; Csaba Szabó; Ádám Németh; Stefanie M Bode-Böger
Effects of coronary revascularization with or without cardiopulmonary bypass on plasma levels of asymmetric dimethylarginine.
Coronary artery disease 2011;22(4):245-52.
2011: Oktay Tutarel; Agnieszka Denecke; Stefanie M Bode-Böger; Jens Martens-Lobenhoffer; Bernhard Schieffer; Mechthild Westhoff-Bleck; Jan T Kielstein
Symmetrical dimethylarginine outperforms CKD-EPI and MDRD-derived eGFR for the assessment of renal function in patients with adult congenital heart disease.
Kidney & blood pressure research 2011;34(1):41-5.
2011: Jan T Kielstein; Hendrik Veldink; Jens Martens-Lobenhoffer; Hermann Haller; Michael Burg; Johan M Lorenzen; Ralf Lichtinghagen; Stefanie M Bode-Böger; Volker Kliem
SDMA is an early marker of change in GFR after living-related kidney donation.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2011;26(1):324-8.
2011: Ines Reiche; Sabine Westphal; Jens Martens-Lobenhoffer; Uwe Tröger; Claus Luley; Stefanie M Bode-Böger
Pharmacokinetics and dose recommendations of Niaspan® in chronic kidney disease and dialysis patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2011;26(1):276-82.
2010: Alessandra D'Alessandro; Oliver Wolfram; Kathleen Jentsch-Ullrich; Jens Martens-Lobenhoffer; Fortunato Scalera; Uwe Lendeckel; Stefanie M Bode-Böger
The effects of G-CSF-induced mobilization of progenitor cells are limited by ADMA.
International journal of cardiology 2010;143(3):264-70.
2010: Sascha David; Philipp Kümpers; Alexander Lukasz; Danilo Fliser; Jens Martens-Lobenhoffer; Stefanie M Bode-Böger; Volker Kliem; Hermann Haller; Jan T Kielstein
Circulating angiopoietin-2 levels increase with progress of chronic kidney disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2010;25(8):2571-6.
2010: Uwe Tröger; Ines Reiche; Marilene S Jepsen; Christof Huth; Stefanie M Bode-Böger
Esomeprazole-induced rhabdomyolysis in a patient with heart failure.
Intensive care medicine 2010;36(7):1278-9.
2010: Ines Reiche; Uwe Tröger; Jens Martens-Lobenhoffer; Arne Kandulski; Helmut Neumann; Peter Malfertheiner; Stefanie M Bode-Böger
Omeprazole-induced cough in a patient with gastroesophageal reflux disease.
European journal of gastroenterology & hepatology 2010;22(7):880-2.
2010: Svenja K Bahte; Anna Bertram; Olaf Burkhardt; Jens Martens-Lobenhoffer; Vega Goedecke; Stefanie M Bode-Böger; Marcus Hiss; Jan T Kielstein
Therapeutic serum concentrations of daptomycin after intraperitoneal administration in a patient with peritoneal dialysis-associated peritonitis.
The Journal of antimicrobial chemotherapy 2010;65(6):1312-4.
2010: Mathias W Pletz; Frank Bloos; Olaf Burkhardt; Frank M Brunkhorst; Stefanie M Bode-Böger; Jens Martens-Lobenhoffer; Mark W Greer; Heino Stass; Tobias Welte
Pharmacokinetics of moxifloxacin in patients with severe sepsis or septic shock.
Intensive care medicine 2010;36(6):979-83.
2010: Zénó Ajtay; Adám Németh; Endre Sulyok; Attila Cziráki; Sandor Szabados; Jens Martens-Lobenhoffer; Friedemann Awiszus; Csaba Szabó; Stefanie M Bode-Böger
Effects of stent implementation on plasma levels of asymmetric dimethylarginine in patients with or without ST-segment elevation acute myocardial infarction.
International journal of molecular medicine 2010;25(4):617-24.
2010: Jens Martens-Lobenhoffer; Christin Dautz; Stefanie M Bode-Böger
Improved method for the determination of cyclic guanosine monophosphate (cGMP) in human plasma by LC-MS/MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2010;878(3-4):487-91.
2010: Stefanie Henken; Jennifer Bohling; Jens Martens-Lobenhoffer; James C Paton; A David Ogunniyi; David E Briles; Vyvyan C Salisbury; Dirk Wedekind; Stefanie M Bode-Böger; Thomas Welsh; Franz C Bange; Tobias Welte; Ulrich A Maus
Efficacy profiles of daptomycin for treatment of invasive and noninvasive pulmonary infections with Streptococcus pneumoniae.
Antimicrobial agents and chemotherapy 2010;54(2):707-17.
2009: Fortunato Scalera; Birthe Fulge; Jens Martens-Lobenhoffer; Anke Heimburg; Stefanie M Bode-Böger
Red wine decreases asymmetric dimethylarginine via SIRT1 induction in human endothelial cells.
Biochemical and biophysical research communications 2009;390(3):703-9.
2009: Fortunato Scalera; Ellen I Closs; Eva Flick; Jens Martens-Lobenhoffer; Jean P Boissel; Uwe Lendeckel; Anke Heimburg; Stefanie M Bode-Böger
Paradoxical effect of L-arginine: acceleration of endothelial cell senescence.
Biochemical and biophysical research communications 2009;386(4):650-5.
2009: Ines Reiche; Uwe Tröger; Sylvia C Postel; Rainer Wolf; Stefanie M Bode-Böger
Valproic acid-induced myopathy in a patient with schizoaffective disorder.
Journal of clinical psychopharmacology 2009;29(4):402-3.
2009: Jens Martens-Lobenhoffer; Achim Becker; Horst Freude; Stefanie M Bode-Böger
Identification and quantification of the atypical metabolite ornithine-lactam in human plasma by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(23):2284-9.
2009: Zénó Ajtay; Fortunato Scalera; Attila Cziráki; Iván Horváth; Lajos Papp; Endre Sulyok; Csaba Szabó; Jens Martens-Lobenhoffer; Friedemann Awiszus; Stefanie M Bode-Böger
Stent placement in patients with coronary heart disease decreases plasma levels of the endogenous nitric oxide synthase inhibitor ADMA.
International journal of molecular medicine 2009;23(5):651-7.
2009: Jan T Kielstein; Gerrit Hesse; Matthias J Bahr; Dimitrios Tsikas; Christoph Terkamp; Jens Martens-Lobenhoffer; Michael P Manns; Hermann Haller; Bernard Panning; Stefanie M Bode-Böger; Michael Gebel
Procedure-related pulmonary hypertension in patients with hepatocellular carcinoma undergoing percutaneous ethanol injection--role of ethanol, hemolysis, asymmetric dimethylarginine, and the nitric oxide system.
Critical care medicine 2009;37(4):1483-5.
2009: Andrzej Surdacki; Jens Martens-Lobenhoffer; Alicja Wloch; Piotr Gluszko; Tomasz Rakowski; Jacek S Dubiel; Stefanie M Bode-Böger
Plasma asymmetric dimethylarginine is related to anticitrullinated protein antibodies in rheumatoid arthritis of short duration.
Metabolism: clinical and experimental 2009;58(3):316-8.
2009: Gabriella Vida; Endre Sulyok; Orsolya Lakatos; Tibor Ertl; Jens Martens-Lobenhoffer; Stefanie M Bode-Böger
Plasma levels of asymmetric dimethylarginine in premature neonates: its possible involvement in developmental programming of chronic diseases.
Acta paediatrica (Oslo, Norway : 1992) 2009;98(3):437-41.
2008: Jens Martens-Lobenhoffer; Jan T Kielstein; Catrin Oye; Stefanie M Bode-Böger
Validated high performance liquid chromatography-UV detection method for the determination of daptomycin in human plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;875(2):546-50.
2008: Jan T Kielstein; Jens Martens-Lobenhoffer; Stefan Vollmer; Stefanie M Bode-Böger
L-Arginine, ADMA, SDMA, creatinine, MDRD formula: detour to renal function testing.
Journal of nephrology 2008;21(6):959-61.
2008: Fortunato Scalera; Jens Martens-Lobenhoffer; Alicja Bukowska; Uwe Lendeckel; Michael Täger; Stefanie M Bode-Böger
Effect of telmisartan on nitric oxide--asymmetrical dimethylarginine system: role of angiotensin II type 1 receptor gamma and peroxisome proliferator activated receptor gamma signaling during endothelial aging.
Hypertension 2008;51(3):696-703.
2007: Jens Martens-Lobenhoffer; Ines Reiche; Uwe Tröger; Klaus Mönkemüller; Peter Malfertheiner; Stefanie M Bode-Böger
Enantioselective quantification of omeprazole and its main metabolites in human serum by chiral HPLC-atmospheric pressure photoionization tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;857(2):301-7.
2007: Jens Martens-Lobenhoffer; Sylvia Postel; Uwe Tröger; Stefanie M Bode-Böger
Determination of ornithine in human plasma by hydrophilic interaction chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;855(2):271-5.
2007: Jens Martens-Lobenhoffer; Endre Sulyok; Endre Czeiter; András Büki; Jana Kohl; Raimund Firsching; Uwe Tröger; Stefanie M Bode-Böger
Determination of cerebrospinal fluid concentrations of arginine and dimethylarginines in patients with subarachnoid haemorrhage.
Journal of neuroscience methods 2007;164(1):155-60.
2007: Stefanie M Bode-Böger; Fortunato Scalera; Louis J Ignarro
The L-arginine paradox: Importance of the L-arginine/asymmetrical dimethylarginine ratio.
Pharmacology & therapeutics 2007;114(3):295-306.
2007: Jens Martens-Lobenhoffer; Stefanie M Bode-Böger
Chromatographic-mass spectrometric methods for the quantification of L-arginine and its methylated metabolites in biological fluids.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;851(1-2):30-41.
2007: Andrzej Surdacki; Jens Martens-Lobenhoffer; Alicja Wloch; Ewa Marewicz; Tomasz Rakowski; Ewa Wieczorek-Surdacka; Jacek S Dubiel; Juliusz Pryjma; Stefanie M Bode-Böger
Elevated plasma asymmetric dimethyl-L-arginine levels are linked to endothelial progenitor cell depletion and carotid atherosclerosis in rheumatoid arthritis.
Arthritis and rheumatism 2007;56(3):809-19.
2007: Sven Walter; Jörn Kuchenbecker; Peter Banditt; Stefanie M Bode-Böger; Wolfgang Behrens-Baumann
Concentration of moxifloxacin in serum and human aqueous humor following a single 400 mg oral dose.
Journal of cataract and refractive surgery 2007;33(3):553-5.
2007: Andrzej Surdacki; Ewa Stochmal; Magdalena Szurkowska; Stefanie M Bode-Böger; Jens Martens-Lobenhoffer; Anna Stochmal; Artur Klecha; Kalina Kawecka-Jaszcz; Jacek S Dubiel; Bohdan Huszno; Zbigniew Szybiński
Nontraditional atherosclerotic risk factors and extent of coronary atherosclerosis in patients with combined impaired fasting glucose and impaired glucose tolerance.
Metabolism: clinical and experimental 2007;56(1):77-86.
2007: Ewa Wieczorek-Surdacka; Andrzej Surdacki; Stefanie M Bode-Böger; Bibianne Schubert; Wladyslaw Sulowicz
Elevated plasma asymmetric dimethyl-L-arginine in a patient with Gordon syndrome.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007;22(1):268-71.
2006: Jan T Kielstein; Frank Donnerstag; Sandra Gasper; Jan Menne; Anousheh Kielstein; Jens Martens-Lobenhoffer; Fortunato Scalera; john cooke; Danilo Fliser; Stefanie M Bode-Böger
ADMA increases arterial stiffness and decreases cerebral blood flow in humans.
Stroke; a journal of cerebral circulation 2006;37(8):2024-9.
2006: Fortunato Scalera; Jens Martens-Lobenhoffer; Michael Täger; Alicja Bukowska; Uwe Lendeckel; Stefanie M Bode-Böger
Effect of L-arginine on asymmetric dimethylarginine (ADMA) or homocysteine-accelerated endothelial cell aging.
Biochemical and biophysical research communications 2006;345(3):1075-82.
2006: Alessandra D'Alessandro; Matthias Hammwöhner; Jutta Dierkes; Jessica Lachmuth; Juergen Dr.Froelich; Helmut Klein; Stefanie M Bode-Böger
Aortic thrombus and pulmonary embolism in a patient with hyperhomocysteinemia.
Nature clinical practice. Cardiovascular medicine 2006;3(7):396-9; quiz following 399.
2006: Jan Menne; Joon-Keun Park; Rahul Agrawal; Carsten Lindschau; Jan T Kielstein; Torsten Kirsch; Axel Marx; Dominik Muller; Ferdinand H Bahlmann; Matthias Meier; Stefanie M Bode-Böger; Hermann Haller; Danilo Fliser
Cellular and molecular mechanisms of tissue protection by lipophilic calcium channel blockers.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(7):994-6.
2006: Stefanie M Bode-Böger; Fortunato Scalera; Jan T Kielstein; Jens Martens-Lobenhoffer; Günter Breithardt; Manfred Fobker; Holger Reinecke
Symmetrical dimethylarginine: a new combined parameter for renal function and extent of coronary artery disease.
Journal of the American Society of Nephrology : JASN 2006;17(4):1128-34.
2006: Sabine Westphal; Elina Taneva; Steffi Kästner; Jens Martens-Lobenhoffer; Stefanie M Bode-Böger; Siegfried Kropf; Jutta Dierkes; Claus Luley
Endothelial dysfunction induced by postprandial lipemia is neutralized by addition of proteins to the fatty meal.
Atherosclerosis 2006;185(2):313-9.
2006: Jens Martens-Lobenhoffer; Stefanie M Bode-Böger
Fast and efficient determination of arginine, symmetric dimethylarginine, and asymmetric dimethylarginine in biological fluids by hydrophilic-interaction liquid chromatography-electrospray tandem mass spectrometry.
Clinical chemistry 2006;52(3):488-93.
2006: Sabine Westphal; Katrin Borucki; Claus Luley; Jens Martens-Lobenhoffer; Stefanie M Bode-Böger
Treatment with niacin lowers ADMA.
Atherosclerosis 2006;184(2):448-50.
2006: Jan T Kielstein; David Czock; Timo Schöpke; Carsten Hafer; Stefanie M Bode-Böger; Ernst Kuse; Frieder Keller; Danilo Fliser
Pharmacokinetics and total elimination of meropenem and vancomycin in intensive care unit patients undergoing extended daily dialysis.
Critical care medicine 2006;34(1):51-6.
2005: Jens Martens-Lobenhoffer; Sabine Westphal; Friedemann Awiszus; Stefanie M Bode-Böger; Claus Luley
Determination of asymmetric dimethylarginine: liquid chromatography-mass spectrometry or ELISA?
Clinical chemistry 2005;51(11):2188-9.
2005: Uwe Tröger; Hartmut Lins; Jean-M Scherrmann; Claus-Werner Wallesch; Stefanie M Bode-Böger
Tetraparesis associated with colchicine is probably due to inhibition by verapamil of the P-glycoprotein efflux pump in the blood-brain barrier.
BMJ (Clinical research ed.) 2005;331(7517):613.
2005: Stefanie M Bode-Böger; Jens Martens-Lobenhoffer; Michael Täger; Henning Schröder; Fortunato Scalera
Aspirin reduces endothelial cell senescence.
Biochemical and biophysical research communications 2005;334(4):1226-32.
2005: Stefanie M Bode-Böger; G Kojda
Organic nitrates in cardiovascular disease.
Cellular and molecular biology (Noisy-le-Grand, France) 2005;51(3):307-20.
2005: Danilo Fliser; Florian Kronenberg; Jan T Kielstein; Christian Morath; Stefanie M Bode-Böger; Hermann Haller; Eberhard Ritz
Asymmetric dimethylarginine and progression of chronic kidney disease: the mild to moderate kidney disease study.
Journal of the American Society of Nephrology : JASN 2005;16(8):2456-61.
2005: Stefanie M Bode-Böger; Fortunato Scalera; Jens Martens-Lobenhoffer
Asymmetric dimethylarginine (ADMA) accelerates cell senescence.
Vascular medicine (London, England) 2005;10 Suppl 1():S65-71.
2005: Jan T Kielstein; Stefanie M Bode-Böger; Gerrit Hesse; Jens Martens-Lobenhoffer; Attila Takacs; Danilo Fliser; Marius M Hoeper
Asymmetrical dimethylarginine in idiopathic pulmonary arterial hypertension.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(7):1414-8.
2005: Jens Martens-Lobenhoffer; Stefanie M Bode-Böger
Determination of levetiracetam in human plasma with minimal sample pretreatment.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;819(1):197-200.
2005: Fortunato Scalera; Jan T Kielstein; Jens Martens-Lobenhoffer; Sylvia C Postel; Michael Täger; Stefanie M Bode-Böger
Erythropoietin increases asymmetric dimethylarginine in endothelial cells: role of dimethylarginine dimethylaminohydrolase.
Journal of the American Society of Nephrology : JASN 2005;16(4):892-8.
2004: Jens Martens-Lobenhoffer; Olga Krug; Stefanie M Bode-Böger
Determination of arginine and asymmetric dimethylarginine (ADMA) in human plasma by liquid chromatography/mass spectrometry with the isotope dilution technique.
Journal of mass spectrometry : JMS 2004;39(11):1287-94.
2004: Jan T Kielstein; Rainer H Böger; Stefanie M Bode-Böger; Jens Martens-Lobenhoffer; Gerhard Lonnemann; Jürgen C Frölich; Hermann Haller; D Fliser
Low dialysance of asymmetric dimethylarginine (ADMA)--in vivo and in vitro evidence of significant protein binding.
Clinical nephrology 2004;62(4):295-300.
2004: Fortunato Scalera; Jürgen Borlak; Bibiana Beckmann; Jens Martens-Lobenhoffer; Thomas Thum; Michael Täger; Stefanie M Bode-Böger
Endogenous nitric oxide synthesis inhibitor asymmetric dimethyl L-arginine accelerates endothelial cell senescence.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(10):1816-22.
2004: Rainer H Böger; Dimitrios Tsikas; Stefanie M Bode-Böger; Laddaval Phivthong-Ngam; Edzard Schwedhelm; Jürgen C Frölich
Hypercholesterolemia impairs basal nitric oxide synthase turnover rate: a study investigating the conversion of L-[guanidino-(15)N(2)]-arginine to (15)N-labeled nitrate by gas chromatography--mass spectrometry.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2004;11(1):1-8.
2004: Karsten Sydow; Burkhard Hornig; Naoshi Arakawa; Stefanie M Bode-Böger; Dimitrios Tsikas; Thomas Münzel; Rainer H Böger
Endothelial dysfunction in patients with peripheral arterial disease and chronic hyperhomocysteinemia: potential role of ADMA.
Vascular medicine (London, England) 2004;9(2):93-101.
2004: Jutta Dierkes; Sabine Westphal; Jens Martens-Lobenhoffer; Claus Luley; Stefanie M Bode-Böger
Fenofibrate increases the L-arginine:ADMA ratio by increase of L-arginine concentration but has no effect on ADMA concentration.
Atherosclerosis 2004;173(2):239-44.
2004: Jan T Kielstein; Burcu Impraim; Solveig Simmel; Stefanie M Bode-Böger; Dimitrios Tsikas; Juergen Dr.Froelich; Marius M Hoeper; Hermann Haller; Danilo Fliser
Cardiovascular effects of systemic nitric oxide synthase inhibition with asymmetrical dimethylarginine in humans.
Circulation 2004;109(2):172-7.
2004: Jan T Kielstein; S Simmel; Stefanie M Bode-Böger; Heinz Jürgen Roth; Heinrich Schmidt-Gayk; Hermann Haller; D Fliser
Subpressor dose asymmetric dimethylarginine modulates renal function in humans through nitric oxide synthase inhibition.
Kidney & blood pressure research 2004;27(3):143-7.
2003: Jens Martens-Lobenhoffer; Stefanie M Bode-Böger
Simultaneous detection of arginine, asymmetric dimethylarginine, symmetric dimethylarginine and citrulline in human plasma and urine applying liquid chromatography-mass spectrometry with very straightforward sample preparation.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;798(2):231-9.
2003: Jan T Kielstein; Stefanie M Bode-Böger; Hermann Haller; Danilo Fliser
Functional changes in the ageing kidney: is there a role for asymmetric dimethylarginine?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(7):1245-8.
2003: Stefanie M Bode-Böger; Jochen Muke; Andrzej Surdacki; Georg Brabant; Rainer H Böger; Jürgen C Frölich
Oral L-arginine improves endothelial function in healthy individuals older than 70 years.
Vascular medicine (London, England) 2003;8(2):77-81.
2003: Danilo Fliser; Jan T Kielstein; Hermann Haller; Stefanie M Bode-Böger
Asymmetric dimethylarginine: a cardiovascular risk factor in renal disease?
Kidney international. Supplement 2003;(84):S37-40.
2003: Jan T Kielstein; Stefanie M Bode-Böger; Juergen Dr.Froelich; Eberhard Ritz; Hermann Haller; Danilo Fliser
Asymmetric dimethylarginine, blood pressure, and renal perfusion in elderly subjects.
Circulation 2003;107(14):1891-5.
2003: Karsten Sydow; Edzard Schwedhelm; Naoshi Arakawa; Stefanie M Bode-Böger; Dimitrios Tsikas; Burkhard Hornig; Jürgen C Frölich; Rainer H Böger
ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins.
Cardiovascular research 2003;57(1):244-52.
2002: Uwe Tröger; Stefanie M Bode-Böger
Methotrexate treatment and mortality in rheumatoid arthritis.
Lancet 2002;360(9339):1096; author reply 1097-8.
2002: Jan T Kielstein; Rainer H Böger; Stefanie M Bode-Böger; Jürgen C Frölich; Hermann Haller; Eberhard Ritz; Danilo Fliser
Marked increase of asymmetric dimethylarginine in patients with incipient primary chronic renal disease.
Journal of the American Society of Nephrology : JASN 2002;13(1):170-6.
2001: Rainer H Böger; S R Lentz; Stefanie M Bode-Böger; H R Knapp; W G Haynes
Elevation of asymmetrical dimethylarginine may mediate endothelial dysfunction during experimental hyperhomocyst(e)inaemia in humans.
Clinical science (London, England : 1979) 2001;100(2):161-7.
2001: Jan T Kielstein; Stefanie M Bode-Böger; Juergen Dr.Froelich; Hermann Haller; R H Böger
Relationship of asymmetric dimethylarginine to dialysis treatment and atherosclerotic disease.
Kidney international. Supplement 2001;78():S9-13.
2000: Dimitrios Tsikas; Rainer H Böger; Jörg Sandmann; Stefanie M Bode-Böger; Jürgen C Frölich
Endogenous nitric oxide synthase inhibitors are responsible for the L-arginine paradox.
FEBS letters 2000;478(1-2):1-3.
2000: Rainer H Böger; Karsten Sydow; Jürgen Borlak; Thomas Thum; Henrike Lenzen; B Schubert; Dimitrios Tsikas; Stefanie M Bode-Böger
LDL cholesterol upregulates synthesis of asymmetrical dimethylarginine in human endothelial cells: involvement of S-adenosylmethionine-dependent methyltransferases.
Circulation research 2000;87(2):99-105.
2000: Rainer H Böger; Stefanie M Bode-Böger; Karsten Sydow; D D Heistad; S R Lentz
Plasma concentration of asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, is elevated in monkeys with hyperhomocyst(e)inemia or hypercholesterolemia.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(6):1557-64.
2000: Stefanie M Bode-Böger; Rainer H Böger; Jan T Kielstein; M Löffler; J Schäffer; Jürgen C Frölich
Role of endogenous nitric oxide in circadian blood pressure regulation in healthy humans and in patients with hypertension or atherosclerosis.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2000;48(2):125-32.
1999: Jan T Kielstein; Rainer H Böger; Stefanie M Bode-Böger; J Schäffer; MM Barbey; Karl-Martin Koch; Jürgen C Frölich
Asymmetric dimethylarginine plasma concentrations differ in patients with end-stage renal disease: relationship to treatment method and atherosclerotic disease.
Journal of the American Society of Nephrology : JASN 1999;10(3):594-600.
1999: Stefanie M Bode-Böger; Rainer H Böger; M Löffler; D Tsikas; G Brabant; Jürgen C Frölich
L-arginine stimulates NO-dependent vasodilation in healthy humans--effect of somatostatin pretreatment.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 1999;47(1):43-50.
1999: RP Brandes; A Behra; C Lebherz; Rainer H Böger; Stefanie M Bode-Böger; A Mügge
Lovastatin maintains nitric oxide--but not EDHF-mediated endothelium-dependent relaxation in the hypercholesterolemic rabbit carotid artery.
Atherosclerosis 1999;142(1):97-104.
1998: Stefanie M Bode-Böger; Rainer H Böger; M Schubert; Jürgen C Frölich
Effects of very low dose and enteric-coated acetylsalicylic acid on prostacyclin and thromboxane formation and on bleeding time in healthy subjects.
European journal of clinical pharmacology 1998;54(9-10):707-14.
1998: Rainer H Böger; Stefanie M Bode-Böger; Laddaval Phivthong-Ngam; RP Brandes; Edzard Schwedhelm; A Mügge; M Böhme; Dimitrios Tsikas; Jürgen C Frölich
Dietary L-arginine and alpha-tocopherol reduce vascular oxidative stress and preserve endothelial function in hypercholesterolemic rabbits via different mechanisms.
Atherosclerosis 1998;141(1):31-43.
1998: Stefanie M Bode-Böger; Rainer H Böger; A Galland; Dimitrios Tsikas; Jürgen C Frölich
L-arginine-induced vasodilation in healthy humans: pharmacokinetic-pharmacodynamic relationship.
British journal of clinical pharmacology 1998;46(5):489-97.
1998: Rainer H Böger; Stefanie M Bode-Böger; W Thiele; Andreas Creutzig; K Alexander; Jürgen C Frölich
Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease.
Journal of the American College of Cardiology 1998;32(5):1336-44.
1998: Laddaval Phivthong-Ngam; Stefanie M Bode-Böger; Rainer H Böger; M Böhme; RP Brandes; A Mügge; Jürgen C Frölich
Dietary L-arginine normalizes endothelin-induced vascular contractions in cholesterol-fed rabbits.
Journal of cardiovascular pharmacology 1998;32(2):300-7.
1998: Stefanie M Bode-Böger; Rainer H Böger; S Kienke; M Böhme; Laddaval Phivthong-Ngam; Dimitrios Tsikas; Jürgen C Frölich
Chronic dietary supplementation with L-arginine inhibits platelet aggregation and thromboxane A2 synthesis in hypercholesterolaemic rabbits in vivo.
Cardiovascular research 1998;37(3):756-64.
1998: Stefanie M Bode-Böger; Rainer H Böger; A Galland; Jürgen C Frölich
Differential inhibition of human platelet aggregation and thromboxane A2 formation by L-arginine in vivo and in vitro.
Naunyn-Schmiedeberg's archives of pharmacology 1998;357(2):143-50.
1998: Rainer H Böger; Stefanie M Bode-Böger; S Kienke; Alexandru C Stan; R Nafe; Jürgen C Frölich
Dietary L-arginine decreases myointimal cell proliferation and vascular monocyte accumulation in cholesterol-fed rabbits.
Atherosclerosis 1998;136(1):67-77.
1997: RP Brandes; A Behra; C Lebherz; Rainer H Böger; Stefanie M Bode-Böger; Laddaval Phivthong-Ngam; A Mügge
N(G)-nitro-L-arginine- and indomethacin-resistant endothelium-dependent relaxation in the rabbit renal artery: effect of hypercholesterolemia.
Atherosclerosis 1997;135(1):49-55.
1997: Rainer H Böger; Stefanie M Bode-Böger; RP Brandes; Laddaval Phivthong-Ngam; M Böhme; R Nafe; A Mügge; Jürgen C Frölich
Dietary L-arginine reduces the progression of atherosclerosis in cholesterol-fed rabbits: comparison with lovastatin.
Circulation 1997;96(4):1282-90.
1997: Rainer H Böger; Stefanie M Bode-Böger
[Endothelial dysfunction in peripheral arterial occlusive disease: from basic research to clinical use].
VASA. Zeitschrift für Gefässkrankheiten 1997;26(3):180-4.
1997: Sebastian M Schellong; Rainer H Böger; Wolfgang Burchert; Stefanie M Bode-Böger; A Galland; Jürgen C Frölich; H Hundeshagen; K Alexander
Dose-related effect of intravenous L-arginine on muscular blood flow of the calf in patients with peripheral vascular disease: a H215O positron emission tomography study.
Clinical science (London, England : 1979) 1997;93(2):159-65.
1997: Rainer H Böger; Stefanie M Bode-Böger; W Thiele; W Junker; K Alexander; Jürgen C Frölich
Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease.
Circulation 1997;95(8):2068-74.
1996: Rainer H Böger; C Skamira; Stefanie M Bode-Böger; G Brabant; A von zur Muhlen; J C Frolich
Nitric oxide may mediate the hemodynamic effects of recombinant growth hormone in patients with acquired growth hormone deficiency. A double-blind, placebo-controlled study.
The Journal of clinical investigation 1996;98(12):2706-13.
1996: Rainer H Böger; Stefanie M Bode-Böger; P Kramme; Dimitrios Tsikas; Frank-Mathias Gutzki; Jürgen C Frölich
Effect of captopril on prostacyclin and nitric oxide formation in healthy human subjects: interaction with low dose acetylsalicylic acid.
British journal of clinical pharmacology 1996;42(6):721-7.
1996: Rainer H Böger; Stefanie M Bode-Böger; Jürgen C Frölich
The L-arginine-nitric oxide pathway: role in atherosclerosis and therapeutic implications.
Atherosclerosis 1996;127(1):1-11.
1996: Stefanie M Bode-Böger; Rainer H Böger; M Kuhn; Jörg Radermacher; Jürgen C Frölich
Recombinant human erythropoietin enhances vasoconstrictor tone via endothelin-1 and constrictor prostanoids.
Kidney international 1996;50(4):1255-61.
1996: Rainer H Böger; A Mügge; Stefanie M Bode-Böger; D Heinzel; M M Höper; J C Frölich
Differential systemic and pulmonary hemodynamic effects of L-arginine in patients with coronary artery disease or primary pulmonary hypertension.
International journal of clinical pharmacology and therapeutics 1996;34(8):323-8.
1996: A Mügge; S Kurucay; Rainer H Böger; Stefanie M Bode-Böger; H J Schäfers; T Wahlers; J C Frölich; P R Lichtlen
Urinary nitrate excretion is increased in cardiac transplanted patients with acute graft rejection.
Clinical transplantation 1996;10(3):298-305.
1996: Stefanie M Bode-Böger; Rainer H Böger; S Kienke; W Junker; Jürgen C Frölich
Elevated L-arginine/dimethylarginine ratio contributes to enhanced systemic NO production by dietary L-arginine in hypercholesterolemic rabbits.
Biochemical and biophysical research communications 1996;219(2):598-603.
1996: Rainer H Böger; Stefanie M Bode-Böger; Jürgen C Frölich
[Pathogenetic aspects of the L-arginine-NO metabolic pathway in arteriosclerosis and possible therapeutic aspects].
VASA. Zeitschrift für Gefässkrankheiten 1996;25(4):305-16.
1996: Rainer H Böger; Stefanie M Bode-Böger; Heiko Alfke
[Restenosis after percutaneous transluminal angioplasty: II. Possibilities for pharmacologic intervention].
VASA. Zeitschrift für Gefässkrankheiten 1996;25(1):21-31.
1996: Heiko Alfke; Rainer H Böger; Stefanie M Bode-Böger
[Restenosis after percutaneous transluminal angioplasty: I. Etiology and clinical significance].
VASA. Zeitschrift für Gefässkrankheiten 1996;25(1):13-20.
1996: Stefanie M Bode-Böger; Rainer H Böger; Heiko Alfke; D Heinzel; Dimitrios Tsikas; A Creutzig; K Alexander; Jürgen C Frölich
L-arginine induces nitric oxide-dependent vasodilation in patients with critical limb ischemia. A randomized, controlled study.
Circulation 1996;93(1):85-90.
1995: Rainer H Böger; Stefanie M Bode-Böger; A Mügge; S Kienke; R Brandes; A Dwenger; Jürgen C Frölich
Supplementation of hypercholesterolaemic rabbits with L-arginine reduces the vascular release of superoxide anions and restores NO production.
Atherosclerosis 1995;117(2):273-84.
1995: Rainer H Böger; Stefanie M Bode-Böger; Jürgen C Frölich
[Intravenous immunoglobulins. Basic principles, selection criteria and indications for preventive and therapeutic administration].
Medizinische Klinik (Munich, Germany : 1983) 1995;90(9):520-6.
1995: Stefanie M Bode-Böger; Rainer H Böger; J C Frölich
[Comments on the contribution by Prof. Dr. S. H. Hohnloser. Sotalol].
Der Internist 1995;36(7):744.
1995: Rainer H Böger; Stefanie M Bode-Böger; E P Schröder; Dimitrios Tsikas; Jürgen C Frölich
Increased prostacyclin production during exercise in untrained and trained men: effect of low-dose aspirin.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;78(5):1832-8.
1994: A Mügge; R P Brandes; Rainer H Böger; A Dwenger; Stefanie M Bode-Böger; S Kienke; Jürgen C Frölich; P R Lichtlen
Vascular release of superoxide radicals is enhanced in hypercholesterolemic rabbits.
Journal of cardiovascular pharmacology 1994;24(6):994-8.
1994: Dimitrios Tsikas; Rainer H Böger; Stefanie M Bode-Böger; Frank-Mathias Gutzki; Jürgen C Frölich
Quantification of nitrite and nitrate in human urine and plasma as pentafluorobenzyl derivatives by gas chromatography-mass spectrometry using their 15N-labelled analogs.
Journal of chromatography. B, Biomedical applications 1994;661(2):185-91.
1994: Stefanie M Bode-Böger; Rainer H Böger; A Creutzig; Dimitrios Tsikas; Frank-Mathias Gutzki; K Alexander; Jürgen C Frölich
L-arginine infusion decreases peripheral arterial resistance and inhibits platelet aggregation in healthy subjects.
Clinical science (London, England : 1979) 1994;87(3):303-10.
1994: C Ranke; Andreas Creutzig; G Luska; H H Wagner; M Galanski; Stefanie M Bode-Böger; Jürgen C Frölich; H J Avenarius; H Hecker; K Alexander
Controlled trial of high- versus low-dose aspirin treatment after percutaneous transluminal angioplasty in patients with peripheral vascular disease.
The Clinical investigator 1994;72(9):673-80.
1994: Dirk O Stichtenoth; Frank-Mathias Gutzki; Dimitrios Tsikas; N Selve; Stefanie M Bode-Böger; Rainer H Böger; Jürgen C Frölich
Increased urinary nitrate excretion in rats with adjuvant arthritis.
Annals of the rheumatic diseases 1994;53(8):547-9.
1994: Stefanie M Bode-Böger; Rainer H Böger; E P Schröder; J C Frölich
Exercise increases systemic nitric oxide production in men.
Journal of cardiovascular risk 1994;1(2):173-8.
1994: Rainer H Böger; Stefanie M Bode-Böger; U Gerecke; Jürgen C Frölich
Long-term administration of L-arginine, L-NAME, and the exogenous NO donor molsidomine modulates urinary nitrate and cGMP excretion in rats.
Cardiovascular research 1994;28(4):494-9.
1993: C Ranke; Andreas Creutzig; G Luska; H H Wagner; M Galanski; Stefanie M Bode-Böger; Jürgen C Frölich; H J Avenarius; H Hecker; K Alexander
[Dose-dependent side effects of acetylsalicylic acid therapy. Results of a prospective randomized clinical study in patients with peripheral arterial occlusive disease].
Medizinische Klinik (Munich, Germany : 1983) 1993;88(10):571-6.
1993: Rainer H Böger; Stefanie M Bode-Böger; Jürgen C Frölich
[Volume replacement therapy with human albumin. Basic principles, differential indications, alternatives].
Medizinische Klinik (Munich, Germany : 1983) 1993;88(6):371-6.
1993: Rainer H Böger; Stefanie M Bode-Böger; Frank-Mathias Gutzki; Dimitrios Tsikas; H P Weskott; Jürgen C Frölich
Rapid and selective inhibition of platelet aggregation and thromboxane formation by intravenous low dose aspirin in man.
Clinical science (London, England : 1979) 1993;84(5):517-24.
1993: Stefanie M Bode-Böger; Rainer H Böger; J C Frölich
[Therapeutic drug monitoring in general practice--indications and interpretation].
Zeitschrift für ärztliche Fortbildung 1993;87(3):201-10.
1992: Stefanie M Bode-Böger; Rainer H Böger; M Kuhn; Jörg Radermacher; Jürgen C Frölich
Endothelin release and shift in prostaglandin balance are involved in the modulation of vascular tone by recombinant erythropoietin.
Journal of cardiovascular pharmacology 1992;20 Suppl 12():S25-8.