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Helge Bode

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Sebastian W Fuchs; Florian Grundmann; Darko Kresovic; Nicholas R Waterfield; Kenan A J Bozhüyük; Alexander O Brachmann; Veronica Dill; Helge B Bode
Formation of 1,3-cyclohexanediones and resorcinols catalyzed by a widely occuring ketosynthase.
Anna Proschak; Gottfried Wilharm; Veronique De Berardinis; Peter Grün; Frank Löhr; Patrice Lubuta; Helge B Bode
Structure and biosynthesis of fimsbactins A-F, siderophores from Acinetobacter baumannii and Acinetobacter baylyi.
Claudia Hornung; Kirsten Jung; Ines Krohn-Molt; Laure Plener; Anja Poehlein; Andrea Pohlen; Andreas Pommerening-Röser; Christel Schmeisser; Martina Schmidt; Hinrich Schulenburg; Eva Spieck; Melanie Blokesch; Edna Bode; Helge B Bode; Andreas Bonge; Rolf Daniel; Katja Dierking; Frederike S Haack; Gabriele Timmermann; Christian Utpatel; Wolfgang R. Streit
The Janthinobacterium sp. HH01 genome encodes a homologue of the V. cholerae CqsA and L. pneumophila LqsA autoinducer synthases.

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All Publications

2013: Sebastian W Fuchs; Florian Grundmann; Darko Kresovic; Nicholas R Waterfield; Kenan A J Bozhüyük; Alexander O Brachmann; Veronica Dill; Helge B Bode
Formation of 1,3-cyclohexanediones and resorcinols catalyzed by a widely occuring ketosynthase.
Angewandte Chemie (International ed. in English) 2013;52(15):4108-12.
2013: Anna Proschak; Gottfried Wilharm; Veronique De Berardinis; Peter Grün; Frank Löhr; Patrice Lubuta; Helge B Bode
Structure and biosynthesis of fimsbactins A-F, siderophores from Acinetobacter baumannii and Acinetobacter baylyi.
Chembiochem : a European journal of chemical biology 2013;14(5):633-8.
2013: Claudia Hornung; Kirsten Jung; Ines Krohn-Molt; Laure Plener; Anja Poehlein; Andrea Pohlen; Andreas Pommerening-Röser; Christel Schmeisser; Martina Schmidt; Hinrich Schulenburg; Eva Spieck; Melanie Blokesch; Edna Bode; Helge B Bode; Andreas Bonge; Rolf Daniel; Katja Dierking; Frederike S Haack; Gabriele Timmermann; Christian Utpatel; Wolfgang R. Streit
The Janthinobacterium sp. HH01 genome encodes a homologue of the V. cholerae CqsA and L. pneumophila LqsA autoinducer synthases.
PloS one 2013;8(2):e55045.
2012: Alexander O Brachmann; Yannick Kopp; Wolfram Lorenzen; Jörn Piel; Daniela Reimer; Eduardo Augusto Alonso; Helge B Bode
Reciprocal cross talk between fatty acid and antibiotic biosynthesis in a nematode symbiont.
Angewandte Chemie (International ed. in English) 2012;51(48):12086-9.
2012: Qiuqin Zhou; James Baum; Ulrich Brandt; Andrea Dowling; Richard H ffrench-Constant; Heinrich Heide; Jens Wöhnert; Helge B Bode
Xentrivalpeptides A-Q: depsipeptide diversification in Xenorhabdus.
Journal of natural products 2012;75(10):1717-22.
2012: Sebastian W Fuchs; Michael Karas; Carsten Kegler; Friederike I Nollmann; Christian C Sachs; Helge B Bode
Neutral loss fragmentation pattern based screening for arginine-rich natural products in Xenorhabdus and Photorhabdus.
Analytical chemistry 2012;84(16):6948-55.
2012: Helge B Bode; Alexander O Brachmann; Christina Dauth; Sebastian W Fuchs; Carsten Kegler; Ferdinand Kirchner; Wolfram Lorenzen; Daniela Reimer; Peter Grün
Determination of the absolute configuration of peptide natural products by using stable isotope labeling and mass spectrometry.
Chemistry (Weinheim an der Bergstrasse, Germany) 2012;18(8):2342-8.
2012: Florian Grundmann; Aunchalee Thanwisai; Edna Bode; Narisara Chantratita; Veronika Dill; Andrea Dowling; Richard H ffrench-Constant; Helge B Bode
Identification and isolation of insecticidal oxazoles from Pseudomonas spp.
Beilstein journal of organic chemistry 2012;8():749-52.
2012: Aunchalee Thanwisai; Nicholas R Waterfield; Helge B Bode; Phan Ke Long; Sharon J Peacock; Natnaree Saiprom; Sarunporn Tandhavanant; Narisara Chantratita
Diversity of Xenorhabdus and Photorhabdus spp. and their symbiotic entomopathogenic nematodes from Thailand.
PloS one 2012;7(9):e43835.
2012: Dawid Brat; Wolfram Lorenzen; Christian Weber; Helge B Bode; Eckhard Boles
Cytosolic re-localization and optimization of valine synthesis and catabolism enables inseased isobutanol production with the yeast Saccharomyces cerevisiae.
Biotechnology for biofuels 2012;5(1):65.
2012: Friederike I Nollmann; Klaus Deckmann; Andrea Dowling; Richard H ffrench-Constant; Sabine Grösch; Marcel Kaiser; Helge B Bode
Synthesis of szentiamide, a depsipeptide from entomopathogenic Xenorhabdus szentirmaii with activity against Plasmodium falciparum.
Beilstein journal of organic chemistry 2012;8():528-33.
2011: Daniela Reimer; Marco Thines; Peter Grün; Klaas M Pos; Helge B Bode
A natural prodrug activation mechanism in nonribosomal peptide synthesis.
Nature chemical biology 2011;7(12):888-90.
2011: Anna Proschak; Katharina Schultz; Alexander O Brachmann; Andrea J Dowling; Richard ffrench-Constant; Jennifer Herrmann; Rolf Müller; Helge B Bode
Cytotoxic fatty acid amides from Xenorhabdus.
Chembiochem : a European journal of chemical biology 2011;12(13):2011-5.
2011: Sebastian W Fuchs; Anna Proschak; Thorsten W Jaskolla; Michael Karas; Helge B Bode
Structure elucidation and biosynthesis of lysine-rich cyclic peptides in Xenorhabdus nematophila.
Organic & biomolecular chemistry 2011;9(9):3130-2.
2011: Maren Kopp; Herbert Irschik; Katja Gemperlein; Kathrin Buntin; Peter Meiser; Kira J Weissman; Helge B Bode; Rolf Müller
Insights into the complex biosynthesis of the leupyrrins in Sorangium cellulosum So ce690.
Molecular bioSystems 2011;7(5):1549-63.
2009: Egbert Hoiczyk; Michael W Ring; Colleen A McHugh; Gertrud Schwär; Edna Bode; Daniel Krug; Matthias O Altmeyer; Jeff Zhiqiang Lu; Helge B Bode
Lipid body formation plays a central role in cell fate determination during developmental differentiation of Myxococcus xanthus.
Molecular microbiology 2009;74(2):497-517.
2009: Dongjin Park; Kristin Ciezki; Ransome van der Hoeven; Swati Singh; Daniela Reimer; Helge B Bode; Steven Forst
Genetic analysis of xenocoumacin antibiotic production in the mutualistic bacterium Xenorhabdus nematophila.
Molecular microbiology 2009;73(5):938-49.
2009: Wolfram Lorenzen; Michael W Ring; Gertrud Schwär; Helge B Bode
Isoprenoids are essential for fruiting body formation in Myxococcus xanthus.
Journal of bacteriology 2009;191(18):5849-53.
2009: Daniela Reimer; Eva Luxenburger; Alexander O Brachmann; Helge B Bode
A new type of pyrrolidine biosynthesis is involved in the late steps of xenocoumacin production in Xenorhabdus nematophila.
Chembiochem : a European journal of chemical biology 2009;10(12):1997-2001.
2009: Michael W Ring; Gertrud Schwär; Helge B Bode
Biosynthesis of 2-hydroxy and iso-even fatty acids is connected to sphingolipid formation in myxobacteria.
Chembiochem : a European journal of chemical biology 2009;10(12):2003-10.
2009: Michael W Ring; Edna Bode; Gertrud Schwär; Helge B Bode
Functional analysis of desaturases from the myxobacterium Myxococcus xanthus.
FEMS microbiology letters 2009;296(1):124-30.
2009: Helge B Bode
Entomopathogenic bacteria as a source of secondary metabolites.
Current opinion in chemical biology 2009;13(2):224-30.
2009: Andy Zöllner; Calin-Aurel Dragan; Dominik Pistorius; Rolf Müller; Helge B Bode; Frank T Peters; Hans H Maurer; Matthias Bureik
Human CYP4Z1 catalyzes the in-chain hydroxylation of lauric acid and myristic acid.
Biological chemistry 2009;390(4):313-7.
2009: Helge B Bode; Michael W Ring; Gertrud Schwär; Matthias O Altmeyer; Carsten Kegler; Ivy R Jose; Mitchell Singer; Rolf Müller
Identification of additional players in the alternative biosynthesis pathway to isovaleryl-CoA in the myxobacterium Myxococcus xanthus.
Chembiochem : a European journal of chemical biology 2009;10(1):128-40.
2009: Helge B Bode
Insects: true pioneers in anti-infective therapy and what we can learn from them.
Angewandte Chemie (International ed. in English) 2009;48(35):6394-6.
2009: Birgit Ohlendorf; Wolfram Lorenzen; Stefan Kehraus; Anja Krick; Helge B Bode; Gabriele M König
Myxotyrosides A and B, Unusual rhamnosides from Myxococcus sp.
Journal of natural products 2009;72(1):82-6.
2008: Silke C Wenzel; Helge B Bode; Irene Kochems; Rolf Müller
A type I/type III polyketide synthase hybrid biosynthetic pathway for the structurally unique ansa compound kendomycin.
Chembiochem : a European journal of chemical biology 2008;9(16):2711-21.
2008: Nicholas R Waterfield; Maria Sanchez-Contreras; Ioannis Eleftherianos; Andrea Dowling; Guowei Yang; Paul Wilkinson; Julian Parkhill; Nicholas Thomson; Stuart E Reynolds; Helge B Bode; Steven Dorus; Richard H ffrench-Constant
Rapid Virulence Annotation (RVA): identification of virulence factors using a bacterial genome library and multiple invertebrate hosts.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(41):15967-72.
2008: Peter Meiser; Kira J Weissman; Helge B Bode; Daniel Krug; Jeroen S Dickschat; Axel Sandmann; Rolf Müller
DKxanthene biosynthesis--understanding the basis for diversity-oriented synthesis in myxobacterial secondary metabolism.
Chemistry & biology 2008;15(8):771-81.
2008: Susan A Joyce; Alexander O Brachmann; Itamar Glazer; Lea Lango; Gertrud Schwär; David J Clarke; Helge B Bode
Bacterial biosynthesis of a multipotent stilbene.
Angewandte Chemie (International ed. in English) 2008;47(10):1942-5.
2007: Helge B Bode; Peter Meiser; Thorsten Klefisch; Niña Socorro d j Cortina; Daniel Krug; Anke Göhring; Gertrud Schwär; Taifo Mahmud; Yasser A Elnakady; Rolf Müller
Mutasynthesis-derived myxalamids and origin of the isobutyryl-CoA starter unit of myxalamid B.
Chembiochem : a European journal of chemical biology 2007;8(17):2139-44.
2007: Bettina Frank; Silke C Wenzel; Helge B Bode; Maren Scharfe; Helmut Blöcker; Rolf Müller
From genetic diversity to metabolic unity: studies on the biosynthesis of aurafurones and aurafuron-like structures in myxobacteria and streptomycetes.
Journal of molecular biology 2007;374(1):24-38.
2007: Alexander O Brachmann; Susan A Joyce; Holger Jenke-Kodama; Gertrud Schwär; David J Clarke; Helge B Bode
A type II polyketide synthase is responsible for anthraquinone biosynthesis in Photorhabdus luminescens.
Chembiochem : a European journal of chemical biology 2007;8(14):1721-8.
2007: Phil Latreille; Stacie Norton; Barry Goldman; John Henkhaus; Nancy Miller; Brad Barbazuk; Helge B Bode; Creg Darby; Zijin Du; Steven Forst; Sophie Gaudriault; Brad Goodner; Heidi Goodrich-Blair; Steven C Slater
Optical mapping as a routine tool for bacterial genome sequence finishing.
BMC genomics 2007;8():321.
2007: Helge B Bode; Rolf Müller
Reversible sugar transfer by glycosyltransferases as a tool for natural product (bio)synthesis.
Angewandte Chemie (International ed. in English) 2007;46(13):2147-50.
2006: Peter Meiser; Helge B Bode; Rolf Müller
The unique DKxanthene secondary metabolite family from the myxobacterium Myxococcus xanthus is required for developmental sporulation.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(50):19128-33.
2006: Alexander O Brachmann; Steven Forst; Ghazala M Furgani; Andras Fodor; Helge B Bode
Xenofuranones A and B: phenylpyruvate dimers from Xenorhabdus szentirmaii.
Journal of natural products 2006;69(12):1830-2.
2006: Helge B Bode
No need to be pure: mix the cultures!
Chemistry & biology 2006;13(12):1245-6.
2006: Michael W Ring; Gertrud Schwär; Verena Thiel; Jeroen S Dickschat; Reiner M Kroppenstedt; Stefan Schulz; Helge B Bode
Novel iso-branched ether lipids as specific markers of developmental sporulation in the myxobacterium Myxococcus xanthus.
The Journal of biological chemistry 2006;281(48):36691-700.
2006: Helge B Bode; Michael W Ring; Gertrud Schwär; Reiner M Kroppenstedt; Armin Dale Kaiser; Rolf Müller
3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation.
Journal of bacteriology 2006;188(18):6524-8.
2006: Helge B Bode; Michael W Ring; Armin Dale Kaiser; Anna C David; Reiner M Kroppenstedt; Gertrud Schwär
Straight-chain fatty acids are dispensable in the myxobacterium Myxococcus xanthus for vegetative growth and fruiting body formation.
Journal of bacteriology 2006;188(15):5632-4.
2006: Helge B Bode; Rolf Müller
Analysis of myxobacterial secondary metabolism goes molecular.
Journal of industrial microbiology & biotechnology 2006;33(7):577-88.
2005: Jeroen S Dickschat; Helge B Bode; Silke C Wenzel; Rolf Müller; Stefan Schulz
Biosynthesis and identification of volatiles released by the myxobacterium Stigmatella aurantiaca.
Chembiochem : a European journal of chemical biology 2005;6(11):2023-33.
2005: Helge B Bode; Rolf Müller
The impact of bacterial genomics on natural product research.
Angewandte Chemie (International ed. in English) 2005;44(42):6828-46.
2005: Jeroen S Dickschat; Helge B Bode; Reiner M Kroppenstedt; Rolf Müller; Stefan Schulz
Biosynthesis of iso-fatty acids in myxobacteria.
Organic & biomolecular chemistry 2005;3(15):2824-31.
2005: Jeroen S Dickschat; Helge B Bode; Taifo Mahmud; Rolf Müller; Stefan Schulz
A novel type of geosmin biosynthesis in myxobacteria.
The Journal of organic chemistry 2005;70(13):5174-82.
2005: Taifo Mahmud; Silke C Wenzel; Eva Wan; Kwun Wah Wen; Helge B Bode; Nikolaos Gaitatzis; Rolf Müller
A biosynthetic pathway to isovaleryl-CoA in myxobacteria: the involvement of the mevalonate pathway.
Chembiochem : a European journal of chemical biology 2005;6(2):322-30.
2005: Helge B Bode; Jeroen S Dickschat; Reiner M Kroppenstedt; Stefan Schulz; Rolf Müller
Biosynthesis of iso-fatty acids in myxobacteria: iso-even fatty acids are derived by alpha-oxidation from iso-odd fatty acids.
Journal of the American Chemical Society 2005;127(2):532-3.
2004: Silke C Wenzel; Helge B Bode
Novel polyene carboxylic acids from Streptomyces.
Journal of natural products 2004;67(9):1631-3.
2004: Helge B Bode; Silke C Wenzel; Herbert Irschik; Gerhard Höfle; Rolf Müller
Unusual biosynthesis of leupyrrins in the myxobacterium Sorangium cellulosum.
Angewandte Chemie (International ed. in English) 2004;43(32):4163-7.
2004: Jeroen S Dickschat; Silke C Wenzel; Helge B Bode; Rolf Müller; Stefan Schulz
Biosynthesis of volatiles by the myxobacterium Myxococcus xanthus.
Chembiochem : a European journal of chemical biology 2004;5(6):778-87.
2003: Helge B Bode; Herbert Irschik; Silke C Wenzel; Hans Reichenbach; Rolf Müller; Gerhard Höfle
The leupyrrins: a structurally unique family of secondary metabolites from the myxobacterium Sorangium cellulosum.
Journal of natural products 2003;66(9):1203-6.
2003: Helge B Bode; Rolf Müller
Possibility of bacterial recruitment of plant genes associated with the biosynthesis of secondary metabolites.
Plant physiology 2003;132(3):1153-61.
2003: Silke Busch; Helge B Bode; Axel A Brakhage; Gerhard H Braus
Impact of the cross-pathway control on the regulation of lysine and penicillin biosynthesis in Aspergillus nidulans.
Current genetics 2003;42(4):209-19.
2003: Helge B Bode; Bernd Zeggel; Barbara Silakowski; Silke C Wenzel; Hans Reichenbach; Rolf Müller
Steroid biosynthesis in prokaryotes: identification of myxobacterial steroids and cloning of the first bacterial 2,3(S)-oxidosqualene cyclase from the myxobacterium Stigmatella aurantiaca.
Molecular microbiology 2003;47(2):471-81.
2002: Taifo Mahmud; Helge B Bode; Barbara Silakowski; Reiner M Kroppenstedt; Mingjie Xu; Sonja Nordhoff; Gerhard Höfle; Rolf Müller
A novel biosynthetic pathway providing precursors for fatty acid biosynthesis and secondary metabolite formation in myxobacteria.
The Journal of biological chemistry 2002;277(36):32768-74.
2002: Helge B Bode; Barbara Bethe; Regina Höfs; Axel Zeeck
Big effects from small changes: possible ways to explore nature's chemical diversity.
Chembiochem : a European journal of chemical biology 2002;3(7):619-27.
2001: Helge B Bode; K Kerkhoff; D Jendrossek
Bacterial degradation of natural and synthetic rubber.
Biomacromolecules 2001;2(1):295-303.
2000: Helge B Bode; Axel Zeeck
UV mutagenesis and enzyme inhibitors as tools to elucidate the late biosynthesis of the spirobisnaphthalenes.
Phytochemistry 2000;55(4):311-6.
2000: Helge B Bode; Axel Zeeck; K Plückhahn; D Jendrossek
Physiological and chemical investigations into microbial degradation of synthetic Poly(cis-1,4-isoprene).
Applied and environmental microbiology 2000;66(9):3680-5.
2000: Helge B Bode; Axel Zeeck
Sphaerolone and dihydrosphaerolone, two bisnaphthyl-pigments from the fungus Sphaeropsidales sp. F-24'707.
Phytochemistry 2000;54(6):597-601.
2000: Helge B Bode; B Wegner; Axel Zeeck
Biosynthesis of cladospirone bisepoxide, a member of the spirobisnaphthalene family.
The Journal of antibiotics 2000;53(2):153-7.