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Larry Sklar

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J Jacob Strouse; George Tegos; Oleg Ursu; Anna Waller; Susan M Young; Cristian Bologa; Mark B Carter; Bruce S Edwards; Annette M Evangelisti; Irena Ivnitski-Steele; Richard Larson; Tudor I Oprea; Dominique Perez; VM Salas; Larry A Sklar
Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters.
J Jacob Strouse; George P Tegos; Oleg Ursu; Anna Waller; Warren S Weiner; Tuanli Yao; Susan M Young; Jeffrey Aubé; Cristian Bologa; Mark B Carter; Stephanie E Chavez; Bruce S Edwards; Annette M Evangelisti; Terry D Foutz; Matthew J Garcia; Jennifer E Golden; Kristine Gouveia; Irena Ivnitski-Steele; Hadya M Khawaja; Richard Larson; Kelin Li; Brooks E Maki; Tudor I Oprea; Dominique Perez; Jerec Ricci; VM Salas; Chad E Schroeder; Denise S Simpson; Larry A Sklar
A selective ATP-binding cassette subfamily g member 2 efflux inhibitor revealed via high-throughput flow cytometry.
Jacob O Agola; Jeffrey Aubé; Tione Buranda; Jennifer E Golden; Lin Hong; Tudor I Oprea; Chad E Schroeder; Denise S Simpson; Larry A Sklar; J Jacob Strouse; Zurab Surviladze; Oleg Ursu; Anna Waller; Angela Wandinger-Ness
A competitive nucleotide binding inhibitor: in vitro characterization of Rab7 GTPase inhibition.

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All Publications

2013: J Jacob Strouse; George Tegos; Oleg Ursu; Anna Waller; Susan M Young; Cristian Bologa; Mark B Carter; Bruce S Edwards; Annette M Evangelisti; Irena Ivnitski-Steele; Richard Larson; Tudor I Oprea; Dominique Perez; VM Salas; Larry A Sklar
Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters.
Analytical biochemistry 2013;437(1):77-87.
2013: J Jacob Strouse; George P Tegos; Oleg Ursu; Anna Waller; Warren S Weiner; Tuanli Yao; Susan M Young; Jeffrey Aubé; Cristian Bologa; Mark B Carter; Stephanie E Chavez; Bruce S Edwards; Annette M Evangelisti; Terry D Foutz; Matthew J Garcia; Jennifer E Golden; Kristine Gouveia; Irena Ivnitski-Steele; Hadya M Khawaja; Richard Larson; Kelin Li; Brooks E Maki; Tudor I Oprea; Dominique Perez; Jerec Ricci; VM Salas; Chad E Schroeder; Denise S Simpson; Larry A Sklar
A selective ATP-binding cassette subfamily g member 2 efflux inhibitor revealed via high-throughput flow cytometry.
Journal of biomolecular screening 2013;18(1):26-38.
2012: Jacob O Agola; Jeffrey Aubé; Tione Buranda; Jennifer E Golden; Lin Hong; Tudor I Oprea; Chad E Schroeder; Denise S Simpson; Larry A Sklar; J Jacob Strouse; Zurab Surviladze; Oleg Ursu; Anna Waller; Angela Wandinger-Ness
A competitive nucleotide binding inhibitor: in vitro characterization of Rab7 GTPase inhibition.
ACS chemical biology 2012;7(6):1095-108.
2012: Bruce S Edwards; Steven W Graves; Mark B Carter; Jun Chen; John J G Tesmer; David M Thal; Jingshu Zhu; Larry A Sklar
Cluster cytometry for high-capacity bioanalysis.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2012;81(5):419-29.
2012: Jun Chen; Claudio de Virgilio; Bruce S Edwards; Terry D Foutz; Jennifer E Golden; Huining Kang; Robbie J Loewith; Nicolas Panchaud; Marie-Pierre Péli-Gulli; Blake R Peterson; Andrew Seeber; Chris Allen; Jeffrey Aubé; Cristian Bologa; Mark B Carter; J Jacob Strouse; Oleg Ursu; Anna Waller; Margaret Werner-Washburne; Tuanli Yao; Susan M Young; Larry A Sklar
Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry.
ACS chemical biology 2012;7(4):715-22.
2012: Chun-Yuan Chan; Sahba Charkhzarrin; Leyma P De Haro; Samuel A Lee; Sandra D Melman; Catherine Prudom; Summer M Raines; Larry A Sklar; Chris Allen; KJ Parra
Inhibitors of V-ATPase proton transport reveal uncoupling functions of tether linking cytosolic and membrane domains of V0 subunit a (Vph1p).
The Journal of biological chemistry 2012;287(13):10236-50.
2012: Alexandre Chigaev; Larry A Sklar
Aspects of VLA-4 and LFA-1 regulation that may contribute to rolling and firm adhesion.
Frontiers in immunology 2012;3():242.
2012: Zurab Surviladze; Susan M Young; Larry A Sklar
High-throughput flow cytometry bead-based multiplex assay for identification of Rho GTPase inhibitors.
Methods in molecular biology (Clifton, N.J.) 2012;827():253-70.
2012: Alexandre Chigaev; Larry A Sklar
Overview: assays for studying integrin-dependent cell adhesion.
Methods in molecular biology (Clifton, N.J.) 2012;757():3-14.
2011: Alexandre Chigaev; Stuart S Winter; Larry A Sklar
Is prolonged stem cell mobilization detrimental for hematopoiesis?
Medical hypotheses 2011;77(6):1111-3.
2011: Megan K Dennis; Angela S Field; Helen J Hathaway; Shin-Ichi Hayashi; Tudor I Oprea; Whitney K Petrie; Jeffrey B Arterburn; Cristian Bologa; Ritwik Burai; Chinnasamy Ramesh; Larry A Sklar; Yuri Yamaguchi; Eric R Prossnitz
Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity.
The Journal of steroid biochemistry and molecular biology 2011;127(3-5):358-66.
2011: Ramona F Curpan; Bruce S Edwards; Tudor I Oprea; John C Reed; Arnold C Satterthwait; Peter C Simons; Cristian Bologa; Mark B Carter; Susan M Young; Dayong Zhai; Larry A Sklar
High-throughput screen for the chemical inhibitors of antiapoptotic bcl-2 family proteins by multiplex flow cytometry.
Assay and drug development technologies 2011;9(5):465-74.
2011: Haixun Guo; Fabio Gallazzi; Larry A Sklar; Yubin Miao
A novel indium-111-labeled gonadotropin-releasing hormone peptide for human prostate cancer imaging.
Bioorganic & medicinal chemistry letters 2011;21(18):5184-7.
2011: Peter C Simons; Mark B Carter; Bruce S Edwards; John C Reed; Anna Waller; Susan M Young; Dayong Zhai; Larry A Sklar
Simultaneous in vitro molecular screening of protein-peptide interactions by flow cytometry, using six Bcl-2 family proteins as examples.
Nature protocols 2011;6(7):943-52.
2011: Gordon J Zwartz; Alexandre Chigaev; Bruce Edwards; Terry D Foutz; Larry A Sklar
A miniature Couette to generate shear for flow cytometry: studying real-time modulation of intracellular calcium in monocytic cells.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2011;79(3):233-40.
2011: Alexandre Chigaev; Yelena Smagley; Larry A Sklar
Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion.
BMC immunology 2011;12():28.
2011: George P Tegos; J Jacob Strouse; Cristian Bologa; Mark Haynes; Mohiuddin Md T Khan; Tudor I Oprea; Larry A Sklar
Microbial efflux pump inhibition: tactics and strategies.
Current pharmaceutical design 2011;17(13):1291-302.
2011: Tione Buranda; Yang Wu; Larry A Sklar
Quantum dots for quantitative flow cytometry.
Methods in molecular biology (Clifton, N.J.) 2011;699():67-84.
2010: Matthew J Saunders; Bruce S Edwards; Jingshu Zhu; Larry A Sklar; Steven W Graves
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Current protocols in cytometry / editorial board, J. Paul Robinson, managing editor ... [et al.] 2010;Chapter 13():Unit 13.12.1-17.
2010: Tapan K Nayak; Megan K Dennis; Chinnasamy Ramesh; Ritwik Burai; Robert W Atcher; Larry A Sklar; Jeffrey P Norenberg; Helen J Hathaway; Jeffrey B Arterburn; Eric R Prossnitz
Influence of charge on cell permeability and tumor imaging of GPR30-targeted 111in-labeled nonsteroidal imaging agents.
ACS chemical biology 2010;5(7):681-90.
2010: Tione Buranda; Yang Wu; Dominique Perez; Stephen D Jett; Virginie BonduHawkins; Chunyan Ye; Bruce Edwards; Pamela Hall; Richard Larson; Gabriel P Lopez; Larry A Sklar; Brian Hjelle
Recognition of decay accelerating factor and alpha(v)beta(3) by inactivated hantaviruses: Toward the development of high-throughput screening flow cytometry assays.
Analytical biochemistry 2010;402(2):151-60.
2010: Ritwik Burai; Chinnasamy Ramesh; Marvin Shorty; Ramona Curpan; Cristian Bologa; Larry A Sklar; Tudor I Oprea; Eric R Prossnitz; Jeffrey B Arterburn
Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs.
Organic & biomolecular chemistry 2010;8(9):2252-9.
2010: Rebecca M Johnson; Chris Allen; Sandra D Melman; Anna Waller; Susan M Young; Larry A Sklar; KJ Parra
Identification of inhibitors of vacuolar proton-translocating ATPase pumps in yeast by high-throughput screening flow cytometry.
Analytical biochemistry 2010;398(2):203-11.
2010: Chinnasamy Ramesh; Tapan K Nayak; Ritwik Burai; Megan K Dennis; Helen J Hathaway; Larry A Sklar; Eric R Prossnitz; Jeffrey B Arterburn
Synthesis and characterization of iodinated tetrahydroquinolines targeting the G protein-coupled estrogen receptor GPR30.
Journal of medicinal chemistry 2010;53(3):1004-14.
2010: Tione Buranda; Yang Wu; Dominique Perez; Alexandre Chigaev; Larry A Sklar
Real-time partitioning of octadecyl rhodamine B into bead-supported lipid bilayer membranes revealing quantitative differences in saturable binding sites in DOPC and 1:1:1 DOPC/SM/cholesterol membranes.
The journal of physical chemistry. B 2010;114(3):1336-49.
2010: Zurab Surviladze; Anna Waller; Yang Wu; Elsa Romero; Bruce S Edwards; Angela Wandinger-Ness; Larry A Sklar
Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay.
Journal of biomolecular screening 2010;15(1):10-20.
2009: Haixun Guo; Jianquan Yang; Fabio Gallazzi; Eric R Prossnitz; Larry A Sklar; Yubin Miao
Effect of DOTA position on melanoma targeting and pharmacokinetic properties of 111In-labeled lactam bridge-cyclized alpha-melanocyte stimulating hormone peptide.
Bioconjugate chemistry 2009;20(11):2162-8.
2009: Irena Ivnitski-Steele; Ann R Holmes; Erwin Lamping; Brian C Monk; Richard D Cannon; Larry A Sklar
Identification of Nile red as a fluorescent substrate of the Candida albicans ATP-binding cassette transporters Cdr1p and Cdr2p and the major facilitator superfamily transporter Mdr1p.
Analytical biochemistry 2009;394(1):87-91.
2009: Ben H Njus; Alexandre Chigaev; Anna Waller; Danuta Wlodek; Liliana Ostopovici-Halip; Oleg Ursu; Wei Wang; Tudor I Oprea; Cristian Bologa; Larry A Sklar
Conformational mAb as a tool for integrin ligand discovery.
Assay and drug development technologies 2009;7(5):507-15.
2009: Tudor I Oprea; Cristian Bologa; Scott Boyer; Ramona F Curpan; Robert C Glen; Andrew L Hopkins; Christopher A Lipinski; Garland R Marshall; Yvonne C Martin; Liliana Ostopovici-Halip; Gilbert Rishton; Oleg Ursu; Roy J Vaz; Chris Waller; Herbert Waldmann; Larry A Sklar
A crowdsourcing evaluation of the NIH chemical probes.
Nature chemical biology 2009;5(7):441-7.
2009: Mark K Haynes; J Jacob Strouse; Anna Waller; Andrei Leitao; Ramona F Curpan; Cristian Bologa; Tudor I Oprea; Eric R Prossnitz; Bruce S Edwards; Larry A Sklar; Todd A Thompson
Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system.
Journal of biomolecular screening 2009;14(6):596-609.
2009: Megan K Dennis; Ritwik Burai; Chinnasamy Ramesh; Whitney K Petrie; Sara N Alcon; Tapan K Nayak; Cristian Bologa; Andrei Leitao; Eugen Brailoiu; Elena Deliu; Nae J Dun; Larry A Sklar; Helen J Hathaway; Jeffrey B Arterburn; Tudor I Oprea; Eric R Prossnitz
In vivo effects of a GPR30 antagonist.
Nature chemical biology 2009;5(6):421-7.
2009: Alexandre Chigaev; Anna Waller; Or Amit; Liliana Halip; Cristian G Bologa; Larry A Sklar
Real-time analysis of conformation-sensitive antibody binding provides new insights into integrin conformational regulation.
The Journal of biological chemistry 2009;284(21):14337-46.
2009: Haixun Guo; Nalini Shenoy; Benjamin M Gershman; Jianquan Yang; Larry A Sklar; Yubin Miao
Metastatic melanoma imaging with an (111)In-labeled lactam bridge-cyclized alpha-melanocyte-stimulating hormone peptide.
Nuclear medicine and biology 2009;36(3):267-76.
2009: J Jacob Strouse; Susan M Young; Hugh D Mitchell; Richard D Ye; Eric R Prossnitz; Larry A Sklar; Bruce S Edwards
A novel fluorescent cross-reactive formylpeptide receptor/formylpeptide receptor-like 1 hexapeptide ligand.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2009;75(3):264-70.
2009: Susan M Young; Cristian M Bologa; Dan Fara; Bj K Bryant; Juan Jacob Strouse; Jeffrey B Arterburn; Richard D Ye; Tudor I Oprea; Eric R Prossnitz; Larry A Sklar; Bruce S Edwards
Duplex high-throughput flow cytometry screen identifies two novel formylpeptide receptor family probes.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2009;75(3):253-63.
2009: Jeffrey B Arterburn; Tudor I Oprea; Eric R Prossnitz; Bruce S Edwards; Larry A Sklar
Discovery of selective probes and antagonists for G-protein-coupled receptors FPR/FPRL1 and GPR30.
Current topics in medicinal chemistry 2009;9(13):1227-36.
2009: Tione Buranda; Yang Wu; Larry A Sklar
Chapter 11. Subsecond analyses of G-protein coupled-receptor ternary complex dynamics by rapid mix flow cytometry.
Methods in enzymology 2009;461():227-47.
2009: Bruce S Edwards; Susan M Young; Irena Ivnitsky-Steele; Richard D Ye; Eric R Prossnitz; Larry A Sklar
High-content screening: flow cytometry analysis.
Methods in molecular biology (Clifton, N.J.) 2009;486():151-65.
2008: Samantha L Schwartz; Mathewos Tessema; Tione Buranda; Olena Pylypenko; Alexey Rak; Peter C Simons; Zurab Surviladze; Larry A Sklar; Angela Wandinger-Ness
Flow cytometry for real-time measurement of guanine nucleotide binding and exchange by Ras-like GTPases.
Analytical biochemistry 2008;381(2):258-66.
2008: Tapan K Nayak; Helen J Hathaway; Chinnasamy Ramesh; Jeffrey B Arterburn; Donghai Dai; Larry A Sklar; Jeffrey P Norenberg; Eric R Prossnitz
Preclinical development of a neutral, estrogen receptor-targeted, tridentate 99mTc(I)-estradiol-pyridin-2-yl hydrazine derivative for imaging of breast and endometrial cancers.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(6):978-86.
2008: Megan K Dennis; Harmony J C Bowles; Debra A MacKenzie; Scott W Burchiel; Bruce S Edwards; Larry A Sklar; Eric R Prossnitz; Todd A Thompson
A multifunctional androgen receptor screening assay using the high-throughput Hypercyt flow cytometry system.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2008;73(5):390-9.
2008: Reema Zeineldin; Menake E Piyasena; Larry A Sklar; David G Whitten; Gabriel P Lopez
Detection of membrane biointeractions based on fluorescence superquenching.
Langmuir : the ACS journal of surfaces and colloids 2008;24(8):4125-31.
2008: Irena Ivnitski-Steele; Richard Larson; Debbie M Lovato; Hadya M Khawaja; Stuart S Winter; Tudor I Oprea; Larry A Sklar; Bruce S Edwards
High-throughput flow cytometry to detect selective inhibitors of ABCB1, ABCC1, and ABCG2 transporters.
Assay and drug development technologies 2008;6(2):263-76.
2008: Stuart S Winter; Debbie M Lovato; Hadya M Khawaja; Bruce S Edwards; Irena D Steele; Susan M Young; Tudor I Oprea; Larry A Sklar; Richard Larson
High-throughput screening for daunorubicin-mediated drug resistance identifies mometasone furoate as a novel ABCB1-reversal agent.
Journal of biomolecular screening 2008;13(3):185-93.
2008: Eric R Prossnitz; Larry A Sklar; Tudor I Oprea; Jeffrey B Arterburn
GPR30: a novel therapeutic target in estrogen-related disease.
Trends in pharmacological sciences 2008;29(3):116-23.
2008: Alexandre Chigaev; Anna Waller; Or Amit; Larry A Sklar
Galphas-coupled receptor signaling actively down-regulates alpha4beta1-integrin affinity: a possible mechanism for cell de-adhesion.
BMC immunology 2008;9():26.
2008: VM Salas; Bruce S Edwards; Larry A Sklar
Advances in multiple analyte profiling.
Advances in clinical chemistry 2008;45():47-74.
2008: Eric R Prossnitz; Jeffrey B Arterburn; Harriet O Smith; Tudor I Oprea; Larry A Sklar; Helen J Hathaway
Estrogen signaling through the transmembrane G protein-coupled receptor GPR30.
Annual review of physiology 2008;70():165-90.
2007: Yang Wu; Tione Buranda; Peter C Simons; Gabriel P Lopez; William E McIntire; James C Garrison; Eric R Prossnitz; Larry A Sklar
Rapid-mix flow cytometry measurements of subsecond regulation of G protein-coupled receptor ternary complex dynamics by guanine nucleotides.
Analytical biochemistry 2007;371(1):10-20.
2007: Mark A Naivar; Jimmie D Parson; Mark E Wilder; Robert C Habbersett; Bruce S Edwards; Larry A Sklar; John P Nolan; Steven W Graves; John C Martin; James H Jett; James P Freyer
Open, reconfigurable cytometric acquisition system: ORCAS.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2007;71(11):915-24.
2007: Larry A Sklar; Mark B Carter; Bruce S Edwards
Flow cytometry for drug discovery, receptor pharmacology and high-throughput screening.
Current opinion in pharmacology 2007;7(5):527-34.
2007: Chetana M Revankar; Hugh D Mitchell; Angela S Field; Ritwik Burai; Cesear Corona; Chinnasamy Ramesh; Larry A Sklar; Jeffrey B Arterburn; Eric R Prossnitz
Synthetic estrogen derivatives demonstrate the functionality of intracellular GPR30.
ACS chemical biology 2007;2(8):536-44.
2007: Peter C Simons; Susan M Young; Veronica Gibaja; Wen-Cherng Lee; Serene Josiah; Bruce S Edwards; Larry A Sklar
Duplexed, bead-based competitive assay for inhibitors of protein kinases.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2007;71(7):451-9.
2007: Alexandre Chigaev; Anna Waller; Gordon Zwartz; Tione Buranda; Larry A Sklar
Regulation of cell adhesion by affinity and conformational unbending of alpha4beta1 integrin.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(11):6828-39.
2007: Yang Wu; Samuel Campos; Gabriel P Lopez; Michelle A Ozbun; Larry A Sklar; Tione Buranda
The development of quantum dot calibration beads and quantitative multicolor bioassays in flow cytometry and microscopy.
Analytical biochemistry 2007;364(2):180-92.
2007: Yang Wu; Gabriel P Lopez; Larry A Sklar; Tione Buranda
Spectroscopic characterization of streptavidin functionalized quantum dots.
Analytical biochemistry 2007;364(2):193-203.
2007: Eric R Prossnitz; Jeffrey B Arterburn; Larry A Sklar
GPR30: A G protein-coupled receptor for estrogen.
Molecular and cellular endocrinology 2007;265-266():138-42.
2007: Tione Buranda; Anna Waller; Yang Wu; Peter C Simons; Sean M Biggs; Eric R Prossnitz; Larry A Sklar
Some mechanistic insights into GPCR activation from detergent-solubilized ternary complexes on beads.
Advances in protein chemistry 2007;74():95-135.
2006: Chinnasamy Ramesh; Bj Bryant; Tapan K Nayak; Chetana M Revankar; Tamara Anderson; Kathryn E Carlson; John A Katzenellenbogen; Larry A Sklar; Jeffrey P Norenberg; Eric R Prossnitz; Jeffrey B Arterburn
Linkage effects on binding affinity and activation of GPR30 and estrogen receptors ERalpha/beta with tridentate pyridin-2-yl hydrazine tricarbonyl-Re/(99m)Tc(I) chelates.
Journal of the American Chemical Society 2006;128(45):14476-7.
2006: Eric R Prossnitz; Larry A Sklar; Jeffrey B Arterburn; Bruce S Edwards; Tudor I Oprea
Steroid-binding G-protein-coupled receptors: new drug discovery targets for old ligands.
Expert opinion on drug discovery 2006;1(2):137-50.
2006: Matthew J Saunders; Heungbok Kim; Travis A Woods; John P Nolan; Larry A Sklar; Bruce S Edwards; Steven W Graves
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2006;69(5):342-52.
2006: Reema Zeineldin; Menake E Piyasena; Troy S Bergstedt; Larry A Sklar; David G Whitten; Gabriel P Lopez
Superquenching as a detector for microsphere-based flow cytometric assays.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2006;69(5):335-41.
2006: Mathewos Tessema; Peter C Simons; Daniel F Cimino; Lilliana Sanchez; Anna Waller; Richard G Posner; Angela Wandinger-Ness; Eric R Prossnitz; Larry A Sklar
Glutathione-S-transferase-green fluorescent protein fusion protein reveals slow dissociation from high site density beads and measures free GSH.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2006;69(5):326-34.
2006: Cristian Bologa; Chetana M Revankar; Susan M Young; Bruce S Edwards; Jeffrey B Arterburn; Alexander S Kiselyov; Matthew A Parker; Sergey E Tkachenko; Nikolay P Savchuck; Larry A Sklar; Tudor I Oprea; Eric R Prossnitz
Virtual and biomolecular screening converge on a selective agonist for GPR30.
Nature chemical biology 2006;2(4):207-12.
2006: Ilya Okun; Sergei Malarchuk; Elena Dubrovskaya; Alexander Khvat; Sergey E Tkachenko; Volodymyr Kysil; Alexey Ilyin; Dmitry Kravchenko; Eric R Prossnitz; Larry A Sklar; Alexandre V Ivachtchenko
Screening for caspase-3 inhibitors: a new class of potent small-molecule inhibitors of caspase-3.
Journal of biomolecular screening 2006;11(3):277-85.
2006: Yang Wu; Tione Buranda; Robert L Metzenberg; Larry A Sklar; Gabriel P Lopez
Diazo coupling method for covalent attachment of proteins to solid substrates.
Bioconjugate chemistry 2006;17(2):359-65.
2006: Eric R Prossnitz; Larry A Sklar
Modulation of GPCR conformations by ligands, G-proteins, and arrestins.
Ernst Schering Foundation symposium proceedings 2006;(2):211-28.
2006: Bruce S Edwards; Susan M Young; Tudor I Oprea; Cristian Bologa; Eric R Prossnitz; Larry A Sklar
Biomolecular screening of formylpeptide receptor ligands with a sensitive, quantitative, high-throughput flow cytometry platform.
Nature protocols 2006;1(1):59-66.
2005: Bruce S Edwards; Cristian Bologa; Susan M Young; Konstantin V Balakin; Eric R Prossnitz; Nikolay P Savchuck; Larry A Sklar; Tudor I Oprea
Integration of virtual screening with high-throughput flow cytometry to identify novel small molecule formylpeptide receptor antagonists.
Molecular pharmacology 2005;68(5):1301-10.
2005: Yang Wu; Gordon Zwartz; Gabriel P Lopez; Larry A Sklar; Tione Buranda
Small-volume rapid-mix device for subsecond kinetic analysis in flow cytometry.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2005;67(1):37-44.
2005: Tudor I Oprea; Cristian Bologa; Bruce S Edwards; Eric R Prossnitz; Larry A Sklar
Post-high-throughput screening analysis: an empirical compound prioritization scheme.
Journal of biomolecular screening 2005;10(5):419-26.
2005: Yang Wu; Peter C Simons; Gabriel P Lopez; Larry A Sklar; Tione Buranda
Dynamics of fluorescence dequenching of ostrich-quenched fluorescein biotin: a multifunctional quantitative assay for biotin.
Analytical biochemistry 2005;342(2):221-8.
2005: Susan M Young; Cristian Bologa; Eric R Prossnitz; Tudor I Oprea; Larry A Sklar; Bruce S Edwards
High-throughput screening with HyperCyt flow cytometry to detect small molecule formylpeptide receptor ligands.
Journal of biomolecular screening 2005;10(4):374-82.
2005: Shalon E Babbitt; Alexi Kiss; Andrew E Deffenbaugh; Yie-Hwa Chang; Eric Bailly; Hediye Erdjument-Bromage; Paul Tempst; Tione Buranda; Larry A Sklar; Jennifer Baumler; Edward Gogol; Dorota Skowyra
ATP hydrolysis-dependent disassembly of the 26S proteasome is part of the catalytic cycle.
Cell 2005;121(4):553-65.
2005: Richard Larson; Terry Davis; Cristian Bologa; Gloria Semenuk; Sreejith Vijayan; Yu Li; Tudor I Oprea; Alexandre Chigaev; Tione Buranda; Carston R Wagner; Larry A Sklar
Dissociation of I domain and global conformational changes in LFA-1: refinement of small molecule-I domain structure-activity relationships.
Biochemistry 2005;44(11):4322-31.
2005: Chetana M Revankar; Daniel F Cimino; Larry A Sklar; Jeffrey B Arterburn; Eric R Prossnitz
A transmembrane intracellular estrogen receptor mediates rapid cell signaling.
Science (New York, N.Y.) 2005;307(5715):1625-30.
2005: T Alexander Key; Charlotte Vines; Brant M Wagener; Vsevolod V Gurevich; Larry A Sklar; Eric R Prossnitz
Inhibition of chemoattractant N-formyl peptide receptor trafficking by active arrestins.
Traffic (Copenhagen, Denmark) 2005;6(2):87-99.
2004: Anna Waller; Peter C Simons; Sean M Biggs; Bruce S Edwards; Eric R Prossnitz; Larry A Sklar
Techniques: GPCR assembly, pharmacology and screening by flow cytometry.
Trends in pharmacological sciences 2004;25(12):663-9.
2004: Menake E Piyasena; Tione Buranda; Yang Wu; Jinman Huang; Larry A Sklar; Gabriel P Lopez
Near-simultaneous and real-time detection of multiple analytes in affinity microcolumns.
Analytical chemistry 2004;76(21):6266-73.
2004: Gordon Zwartz; Alexandre Chigaev; Denise C Dwyer; Terry D Foutz; Bruce S Edwards; Larry A Sklar
Real-time analysis of very late antigen-4 affinity modulation by shear.
The Journal of biological chemistry 2004;279(37):38277-86.
2004: Bruce S Edwards; Tudor I Oprea; Eric R Prossnitz; Larry A Sklar
Flow cytometry for high-throughput, high-content screening.
Current opinion in chemical biology 2004;8(4):392-8.
2004: Alexandre Chigaev; Gordon Zwartz; Tione Buranda; Bruce S Edwards; Eric R Prossnitz; Larry A Sklar
Conformational regulation of alpha 4 beta 1-integrin affinity by reducing agents. "Inside-out" signaling is independent of and additive to reduction-regulated integrin activation.
The Journal of biological chemistry 2004;279(31):32435-43.
2004: Joseph W Bartsch; Hy D Tran; Anna Waller; Andrea A Mammoli; Tione Buranda; Larry A Sklar; Bruce S Edwards
An investigation of liquid carryover and sample residual for a high-throughput flow cytometer sample delivery system.
Analytical chemistry 2004;76(13):3810-7.
2004: Valerie Hernandez-Hansen; Alexander J Smith; Zurab Surviladze; Alexandre Chigaev; Tomas Mazel; Janet Kalesnikoff; Clifford A Lowell; Gerald Krystal; Larry A Sklar; Bridget S Wilson; Janet M Oliver
Dysregulated FcepsilonRI signaling and altered Fyn and SHIP activities in Lyn-deficient mast cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(1):100-12.
2004: Larry A Sklar; H Tsuji; Bruce S Edwards; Richard Larson; Mark Schuyler
Eosinophil traffic in the circulation following allergen challenge.
Allergy 2004;59(6):596-605.
2004: Peter C Simons; Sean M Biggs; Anna Waller; Terry D Foutz; Daniel F Cimino; Qing Guo; Richard Neubig; Wei-Jen Tang; Eric R Prossnitz; Larry A Sklar
Real-time analysis of ternary complex on particles: direct evidence for partial agonism at the agonist-receptor-G protein complex assembly step of signal transduction.
The Journal of biological chemistry 2004;279(14):13514-21.
2004: Susan M Young; Mark S Curry; John T Ransom; Juan A Ballesteros; Eric R Prossnitz; Larry A Sklar; Bruce S Edwards
High-throughput microfluidic mixing and multiparametric cell sorting for bioactive compound screening.
Journal of biomolecular screening 2004;9(2):103-11.
2004: Gordon Zwartz; Alexandre Chigaev; Terry D Foutz; Richard Larson; Richard G Posner; Larry A Sklar
Relationship between molecular and cellular dissociation rates for VLA-4/VCAM-1 interaction in the absence of shear stress.
Biophysical journal 2004;86(2):1243-52.
2003: Alexandre Chigaev; Tione Buranda; Denise C Dwyer; Eric R Prossnitz; Larry A Sklar
FRET detection of cellular alpha4-integrin conformational activation.
Biophysical journal 2003;85(6):3951-62.
2003: Peter C Simons; Mei Shi; Terry D Foutz; Daniel F Cimino; Jeremy Lewis; Tione Buranda; William K Lim; Richard Neubig; William E McIntire; James C Garrison; Eric R Prossnitz; Larry A Sklar
Ligand-receptor-G-protein molecular assemblies on beads for mechanistic studies and screening by flow cytometry.
Molecular pharmacology 2003;64(5):1227-38.
2003: Alexandre Chigaev; Gordon Zwartz; Steven W Graves; Denise C Dwyer; Hisashi Tsuji; Terry D Foutz; Bruce S Edwards; Eric R Prossnitz; Richard Larson; Larry A Sklar
Alpha4beta1 integrin affinity changes govern cell adhesion.
The Journal of biological chemistry 2003;278(40):38174-82.
2003: Andrew E Deffenbaugh; kenneth Scaglione; Lingxiao Zhang; Johnnie M Moore; Tione Buranda; Larry A Sklar; Dorota Skowyra
Release of ubiquitin-charged Cdc34-S - Ub from the RING domain is essential for ubiquitination of the SCF(Cdc4)-bound substrate Sic1.
Cell 2003;114(5):611-22.
2003: Mei Shi; Teresa A Bennett; Daniel F Cimino; Diane C Maestas; Terry D Foutz; Vsevolod V Gurevich; Larry A Sklar; Eric R Prossnitz
Functional capabilities of an N-formyl peptide receptor-G(alpha)(i)(2) fusion protein: assemblies with G proteins and arrestins.
Biochemistry 2003;42(24):7283-93.
2003: R A Truesdell; Peter Vorobieff; Larry A Sklar; Andrea A Mammoli
Mixing of a continuous flow of two fluids due to unsteady flow.
Physical review. E, Statistical, nonlinear, and soft matter physics 2003;67(6 Pt 2):066304.
2003: Anna Waller; Peter C Simons; Eric R Prossnitz; Bruce S Edwards; Larry A Sklar
High throughput screening of G-protein coupled receptors via flow cytometry.
Combinatorial chemistry & high throughput screening 2003;6(4):389-97.
2003: Sergio Ramirez; Charity T Aiken; Brett Andrzejewski; Larry A Sklar; Bruce S Edwards
High-throughput flow cytometry: validation in microvolume bioassays.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2003;53(1):55-65.
2003: T Alexander Key; Terry D Foutz; Vsevolod V Gurevich; Larry A Sklar; Eric R Prossnitz
N-formyl peptide receptor phosphorylation domains differentially regulate arrestin and agonist affinity.
The Journal of biological chemistry 2003;278(6):4041-7.
2002: Richard G Posner; Paul B Savage; Adam S Peters; Angelica Macias; Jamael DelGado; Gordon Zwartz; Larry A Sklar; William S Hlavacek
A quantitative approach for studying IgE-FcepsilonRI aggregation.
Molecular immunology 2002;38(16-18):1221-8.
2002: Christopher L Kepley; Ronald P Andrews; David C Brown; Alexandre Chigaev; Larry A Sklar; Janet M Oliver; Richard Larson
Regulation of human basophil adhesion to endothelium under flow conditions: Different very late antigen 4 regulation on umbilical cord blood-derived and peripheral blood basophils.
The Journal of allergy and clinical immunology 2002;110(3):469-75.
2002: W Coyt Jackson; Teresa A Bennett; Bruce S Edwards; Eric R Prossnitz; Gabriel P Lopez; Larry A Sklar
Performance of in-line microfluidic mixers in laminar flow for high-throughput flow cytometry.
BioTechniques 2002;33(1):220-6.
2002: Ross M Potter; T Alexander Key; Vsevolod V Gurevich; Larry A Sklar; Eric R Prossnitz
Arrestin variants display differential binding characteristics for the phosphorylated N-formyl peptide receptor carboxyl terminus.
The Journal of biological chemistry 2002;277(11):8970-8.
2002: Tione Buranda; Jinman Huang; Victor H Perez-Luna; Brett Schreyer; Larry A Sklar; Gabriel P Lopez
Biomolecular recognition on well-characterized beads packed in microfluidic channels.
Analytical chemistry 2002;74(5):1149-56.
2002: W Coyt Jackson; FW Kuckuck; Bruce S Edwards; Andrea A Mammoli; C M Gallegos; Gabriel P Lopez; Tione Buranda; Larry A Sklar
Mixing small volumes for continuous high-throughput flow cytometry: performance of a mixing Y and peristaltic sample delivery.
Cytometry 2002;47(3):183-91.
2002: Steven W Graves; John P Nolan; James H Jett; John C Martin; Larry A Sklar
Nozzle design parameters and their effects on rapid sample delivery in flow cytometry.
Cytometry 2002;47(2):127-37.
2002: Larry A Sklar; Bruce S Edwards; Steven W Graves; John P Nolan; Eric R Prossnitz
Flow cytometric analysis of ligand-receptor interactions and molecular assemblies.
Annual review of biophysics and biomolecular structure 2002;31():97-119.
2002: Víctor H Pérez-Luna; Saipeng Yang; Emmanuil M Rabinovich; Tione Buranda; Larry A Sklar; Philip D Hampton; Gabriel P López
Fluorescence biosensing strategy based on energy transfer between fluorescently labeled receptors and a metallic surface.
Biosensors & bioelectronics 2002;17(1-2):71-8.
2002: John P Nolan; Larry A Sklar
Suspension array technology: evolution of the flat-array paradigm.
Trends in biotechnology 2002;20(1):9-12.
2001: Alexandre Chigaev; A M Blenc; J V Braaten; N Kumaraswamy; Christopher L Kepley; Ronald P Andrews; Janet M Oliver; Bruce S Edwards; Eric R Prossnitz; Richard Larson; Larry A Sklar
Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn(2+) or antibody activation.
The Journal of biological chemistry 2001;276(52):48670-8.
2001: Teresa A Bennett; Terry D Foutz; Vsevolod V Gurevich; Larry A Sklar; Eric R Prossnitz
Partial phosphorylation of the N-formyl peptide receptor inhibits G protein association independent of arrestin binding.
The Journal of biological chemistry 2001;276(52):49195-203.
2001: T Alexander Key; Teresa A Bennett; Terry D Foutz; Vsevolod V Gurevich; Larry A Sklar; Eric R Prossnitz
Regulation of formyl peptide receptor agonist affinity by reconstitution with arrestins and heterotrimeric G proteins.
The Journal of biological chemistry 2001;276(52):49204-12.
2001: Tione Buranda; Gabriel P Lopez; Peter C Simons; Andrzej Pastuszyn; Larry A Sklar
Detection of epitope-tagged proteins in flow cytometry: fluorescence resonance energy transfer-based assays on beads with femtomole resolution.
Analytical biochemistry 2001;298(2):151-62.
2001: Teresa A Bennett; T Alexander Key; Vsevolod V Gurevich; Richard Neubig; Eric R Prossnitz; Larry A Sklar
Real-time analysis of G protein-coupled receptor reconstitution in a solubilized system.
The Journal of biological chemistry 2001;276(25):22453-60.
2001: FW Kuckuck; Bruce S Edwards; Larry A Sklar
High throughput flow cytometry.
Cytometry 2001;44(1):83-90.
2001: Bruce S Edwards; FW Kuckuck; Eric R Prossnitz; John T Ransom; Larry A Sklar
HTPS flow cytometry: a novel platform for automated high throughput drug discovery and characterization.
Journal of biomolecular screening 2001;6(2):83-90.
2001: Bruce S Edwards; FW Kuckuck; Eric R Prossnitz; A Okun; John T Ransom; Larry A Sklar
Plug flow cytometry extends analytical capabilities in cell adhesion and receptor pharmacology.
Cytometry 2001;43(3):211-6.
2000: Scott W Burchiel; Bruce S Edwards; FW Kuckuck; Fredine T Lauer; Eric R Prossnitz; John T Ransom; Larry A Sklar
Analysis of free intracellular calcium by flow cytometry: multiparameter and pharmacologic applications.
Methods (San Diego, Calif.) 2000;21(3):221-30.
2000: Bruce S Edwards; Mark S Curry; H Tsuji; D Brown; Richard Larson; Larry A Sklar
Expression of P-selectin at low site density promotes selective attachment of eosinophils over neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(1):404-10.
2000: Larry A Sklar; J Vilven; E Lynam; D Neldon; Teresa A Bennett; Eric R Prossnitz
Solubilization and display of G protein-coupled receptors on beads for real-time fluorescence and flow cytometric analysis.
BioTechniques 2000;28(5):976-80, 982-5.
2000: Teresa A Bennett; Bruce S Edwards; Larry A Sklar; S Rogelj
Sulfhydryl regulation of L-selectin shedding: phenylarsine oxide promotes activation-independent L-selectin shedding from leukocytes.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(8):4120-9.
1999: Bruce S Edwards; FW Kuckuck; Larry A Sklar
Plug flow cytometry: An automated coupling device for rapid sequential flow cytometric sample analysis.
Cytometry 1999;37(2):156-9.
1999: Tione Buranda; Gabriel P Lopez; J Keij; R Harris; Larry A Sklar
Peptides, antibodies, and FRET on beads in flow cytometry: A model system using fluoresceinated and biotinylated beta-endorphin.
Cytometry 1999;37(1):21-31.
1999: Eric R Prossnitz; TL Gilbert; S Chiang; J J Campbell; S Qin; W Newman; Larry A Sklar; Richard D Ye
Multiple activation steps of the N-formyl peptide receptor.
Biochemistry 1999;38(8):2240-7.
1999: LC Seamer; FW Kuckuck; Larry A Sklar
Sheath fluid control to permit stable flow in rapid mix flow cytometry.
Cytometry 1999;35(1):75-9.
1999: TL Gilbert; Eric R Prossnitz; Larry A Sklar
The uncoupled state of the human formyl peptide receptor.
Journal of receptor and signal transduction research 1999;19(1-4):327-40.
1999: G M Jones; Carla Wofsy; C Aurell; Larry A Sklar
Analysis of vertical fluorescence resonance energy transfer from the surface of a small-diameter sphere.
Biophysical journal 1999;76(1 Pt 1):517-27.
1998: E Lynam; Larry A Sklar; AD Taylor; Sriram Neelamegham; Bruce S Edwards; C Wayne Smith; Scott I Simon
Beta2-integrins mediate stable adhesion in collisional interactions between neutrophils and ICAM-1-expressing cells.
Journal of leukocyte biology 1998;64(5):622-30.
1998: J C Vilven; M Domalewski; Eric R Prossnitz; Richard D Ye; N Muthukumaraswamy; R B Harris; R J Freer; Larry A Sklar
Strategies for positioning fluorescent probes and crosslinkers on formyl peptide ligands.
Journal of receptor and signal transduction research 1998;18(2-3):187-221.
1997: A L Hall; Bridget S Wilson; Janet R Pfeiffer; Janet M Oliver; Larry A Sklar
Relationship of ligand-receptor dynamics to actin polymerization in RBL-2H3 cells transfected with the human formyl peptide receptor.
Journal of leukocyte biology 1997;62(4):535-46.
1997: Richard Larson; David C Brown; Larry A Sklar
Retinoic acid induces aggregation of the acute promyelocytic leukemia cell line NB-4 by utilization of LFA-1 and ICAM-2.
Blood 1997;90(7):2747-56.
1997: RJ Lee; DE Lujan; A L Hall; Larry A Sklar; Bridget S Wilson; Janet M Oliver
Cooperation between the Fc epsilonR1 and formyl peptide receptor signaling pathways in RBL(FPR) cells: the contribution of receptor-specific Ca2+ mobilization responses.
Biochemical and biophysical research communications 1997;235(3):812-9.
1997: M C Roslaniec; CS Bell-Prince; Harry A Crissman; John J Fawcett; Peter M Goodwin; Robert C Habbersett; James H Jett; Richard A Keller; John C Martin; Babetta L Marrone; John P Nolan; M S Park; BL Sailer; Larry A Sklar; John A Steinkamp; L Scott Cram
New flow cytometric technologies for the 21st century.
Human cell 1997;10(1):3-10.
1996: C Deka; Bruce E Lehnert; NM Lehnert; G M Jones; Larry A Sklar; John A Steinkamp
Analysis of fluorescence lifetime and quenching of FITC-conjugated antibodies on cells by phase-sensitive flow cytometry.
Cytometry 1996;25(3):271-9.
1996: D A Guyer; K L Moore; E B Lynam; C M Schammel; S Rogelj; R P McEver; Larry A Sklar
P-selectin glycoprotein ligand-1 (PSGL-1) is a ligand for L-selectin in neutrophil aggregation.
Blood 1996;88(7):2415-21.
1996: John P Nolan; B Shen; MS Park; Larry A Sklar
Kinetic analysis of human flap endonuclease-1 by flow cytometry.
Biochemistry 1996;35(36):11668-76.
1996: E B Lynam; S Rogelj; B S Edwards; Larry A Sklar
Enhanced aggregation of human neutrophils by MnCl2 or DTT differentiates the roles of L-selectin and beta 2-integrins.
Journal of leukocyte biology 1996;60(3):356-64.
1996: T A Bennett; E B Lynam; Larry A Sklar; S Rogelj
Hydroxamate-based metalloprotease inhibitor blocks shedding of L-selectin adhesion molecule from leukocytes: functional consequences for neutrophil aggregation.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(9):3093-7.
1996: B Shen; John P Nolan; Larry A Sklar; MS Park
Essential amino acids for substrate binding and catalysis of human flap endonuclease 1.
The Journal of biological chemistry 1996;271(16):9173-6.
1996: C A Wiström; G M Jones; P S Tobias; Larry A Sklar
Fluorescence resonance energy transfer analysis of lipopolysaccharide in detergent micelles.
Biophysical journal 1996;70(2):988-97.
1996: M D Domalewski; D A Guyer; R J Freer; N Muthukumaraswamy; Larry A Sklar
Fixation traps formyl peptide receptors in high and low affinity forms that can be regulated by GTP[S] in the absence of ligand.
Journal of receptor and signal transduction research 1996;16(1-2):59-75.
1995: C Deka; L Scott Cram; Robert C Habbersett; J C Martin; Larry A Sklar; John A Steinkamp
Simultaneous dual-frequency phase-sensitive flow cytometric measurements for rapid identification of heterogeneous fluorescence decays in fluorochrome-labeled cells and particles.
Cytometry 1995;21(4):318-28.
1995: John P Nolan; Richard G Posner; J C Martin; Robert C Habbersett; Larry A Sklar
A rapid mix flow cytometer with subsecond kinetic resolution.
Cytometry 1995;21(3):223-9.
1995: T A Bennett; C M Schammel; E B Lynam; D A Guyer; A Mellors; B Edwards; S Rogelj; Larry A Sklar
Evidence for a third component in neutrophil aggregation: potential roles of O-linked glycoproteins as L-selectin counter-structures.
Journal of leukocyte biology 1995;58(5):510-8.
1995: Scott I Simon; Alan R Burns; AD Taylor; P K Gopalan; E B Lynam; Larry A Sklar; C Wayne Smith
L-selectin (CD62L) cross-linking signals neutrophil adhesive functions via the Mac-1 (CD11b/CD18) beta 2-integrin.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(3):1502-14.
1994: C Deka; Larry A Sklar; John A Steinkamp
Fluorescence lifetime measurements in a flow cytometer by amplitude demodulation using digital data acquisition technique.
Cytometry 1994;17(1):94-101.
1994: E B Lynam; Scott I Simon; Y P Rochon; Larry A Sklar
Lipopolysaccharide enhances CD11b/CD18 function but inhibits neutrophil aggregation.
Blood 1994;83(11):3303-11.
1994: Y P Rochon; Scott I Simon; E B Lynam; Larry A Sklar
A role for lectin interactions during human neutrophil aggregation.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(3):1385-93.
1994: Richard G Posner; S P Fay; M D Domalewski; Larry A Sklar
Continuous spectrofluorometric analysis of formyl peptide receptor ternary complex interactions.
Molecular pharmacology 1994;45(1):65-73.
1993: Scott I Simon; Y P Rochon; E B Lynam; C Wayne Smith; D C Anderson; Larry A Sklar
Beta 2-integrin and L-selectin are obligatory receptors in neutrophil aggregation.
Blood 1993;82(4):1097-106.
1993: J D Chambers; Scott I Simon; E M Berger; Larry A Sklar; KE Arfors
Endocytosis of beta 2 integrins by stimulated human neutrophils analyzed by flow cytometry.
Journal of leukocyte biology 1993;53(4):462-9.
1993: S P Fay; M D Domalewski; Larry A Sklar
Evidence for protonation in the human neutrophil formyl peptide receptor binding pocket.
Biochemistry 1993;32(6):1627-31.
1992: Scott I Simon; J D Chambers; Eugene C Butcher; Larry A Sklar
Neutrophil aggregation is beta 2-integrin- and L-selectin-dependent in blood and isolated cells.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(8):2765-71.
1991: S P Fay; Richard G Posner; W N Swann; Larry A Sklar
Real-time analysis of the assembly of ligand, receptor, and G protein by quantitative fluorescence flow cytometry.
Biochemistry 1991;30(20):5066-75.
1991: Johannes Norgauer; M Eberle; S P Fay; H D Lemke; Larry A Sklar
Kinetics of N-formyl peptide receptor up-regulation during stimulation in human neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(3):975-80.
1991: Larry A Sklar; S P Fay; H Mueller; R J Freer; N Muthukumaraswamy; D Magde
Conformational dynamics of the formyl peptide receptor: a prototype for studies of receptor dynamics and binding pocket structure.
Agents and actions. Supplements 1991;35():11-6.
1990: Scott I Simon; J D Chambers; Larry A Sklar
Flow cytometric analysis and modeling of cell-cell adhesive interactions: the neutrophil as a model.
The Journal of cell biology 1990;111(6 Pt 1):2747-56.
1990: M Eberle; Alexis E Traynor-Kaplan; Larry A Sklar; Johannes Norgauer
Is there a relationship between phosphatidylinositol trisphosphate and F-actin polymerization in human neutrophils?
The Journal of biological chemistry 1990;265(28):16725-8.
1990: Larry A Sklar; S P Fay; B E Seligmann; R J Freer; N Muthukumaraswamy; H Mueller
Fluorescence analysis of the size of a binding pocket of a peptide receptor at natural abundance.
Biochemistry 1990;29(2):313-6.