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Mark Sleeman

Research Profile

Chemicals & Drugs

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Pectobacterium

Phenomena

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Mass Spectrometry

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Publications

TOP 3
Mark C Sleeman; John L Sorensen; Edward T Batchelar; Michael McDonough; Christopher J Schofield
Structural and mechanistic studies on carboxymethylproline synthase (CarB), a unique member of the crotonase superfamily catalyzing the first step in carbapenem biosynthesis.
Nadia J Kershaw; Matthew E C Caines; Mark C Sleeman; Christopher J Schofield
The enzymology of clavam and carbapenem biosynthesis.
John L Sorensen; Mark C Sleeman; Christopher J Schofield
Synthesis of deuterium labelled L- and D-glutamate semialdehydes and their evaluation as substrates for carboxymethylproline synthase (CarB)--implications for carbapenem biosynthesis.

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All Publications

2005: Mark C Sleeman; John L Sorensen; Edward T Batchelar; Michael McDonough; Christopher J Schofield
Structural and mechanistic studies on carboxymethylproline synthase (CarB), a unique member of the crotonase superfamily catalyzing the first step in carbapenem biosynthesis.
The Journal of biological chemistry 2005;280(41):34956-65.
2005: Nadia J Kershaw; Matthew E C Caines; Mark C Sleeman; Christopher J Schofield
The enzymology of clavam and carbapenem biosynthesis.
Chemical communications (Cambridge, England) 2005;(34):4251-63.
2005: John L Sorensen; Mark C Sleeman; Christopher J Schofield
Synthesis of deuterium labelled L- and D-glutamate semialdehydes and their evaluation as substrates for carboxymethylproline synthase (CarB)--implications for carbapenem biosynthesis.
Chemical communications (Cambridge, England) 2005;(9):1155-7.
2004: Mark C Sleeman; Paul Smith; Barrie Kellam; Siri Ram Chhabra; Barrie W Bycroft; Christopher J Schofield
Biosynthesis of carbapenem antibiotics: new carbapenam substrates for carbapenem synthase (CarC).
Chembiochem : a European journal of chemical biology 2004;5(6):879-82.
2004: Mark C Sleeman; Christopher J Schofield
Carboxymethylproline synthase (CarB), an unusual carbon-carbon bond-forming enzyme of the crotonase superfamily involved in carbapenem biosynthesis.
The Journal of biological chemistry 2004;279(8):6730-6.

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