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Guido Slegers

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Eva Vandermeulen; Hamphrey R Ham; André A Dobbeleir; Carlos De Sadeleer; Amy Piepsz; Tim Waelbers; Simon Vermeire; Guido Slegers; Kathelijne Y Peremans
(99m)Tc-DMSA absolute and relative renal uptake in cats: procedure and normal values.
Kathelijne Peremans; S Vermeire; André Dobbeleir; Ingrid M Gielen; Y Samoy; K Piron; E Vandermeulen; Guido Slegers; Henri van Bree; B De Spiegeleer; K Dik
Recognition of anatomical predilection sites in canine elbow pathology on bone scans using micro-single photon emission tomography.
Eva Vandermeulen; Carlos De Sadeleer; Amy Piepsz; Hamphrey R Ham; André A Dobbeleir; Simon Vermeire; Ingrid M Van Hoek; sylvie daminet; Guido Slegers; Kathelijne Y Peremans
Determination of optimal sampling times for a two blood sample clearance method using (51)Cr-EDTA in cats.

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2011: Eva Vandermeulen; Hamphrey R Ham; André A Dobbeleir; Carlos De Sadeleer; Amy Piepsz; Tim Waelbers; Simon Vermeire; Guido Slegers; Kathelijne Y Peremans
(99m)Tc-DMSA absolute and relative renal uptake in cats: procedure and normal values.
Journal of feline medicine and surgery 2011;13(6):387-92.
2011: Kathelijne Peremans; S Vermeire; André Dobbeleir; Ingrid M Gielen; Y Samoy; K Piron; E Vandermeulen; Guido Slegers; Henri van Bree; B De Spiegeleer; K Dik
Recognition of anatomical predilection sites in canine elbow pathology on bone scans using micro-single photon emission tomography.
Veterinary journal (London, England : 1997) 2011;188(1):64-72.
2010: Eva Vandermeulen; Carlos De Sadeleer; Amy Piepsz; Hamphrey R Ham; André A Dobbeleir; Simon Vermeire; Ingrid M Van Hoek; sylvie daminet; Guido Slegers; Kathelijne Y Peremans
Determination of optimal sampling times for a two blood sample clearance method using (51)Cr-EDTA in cats.
Journal of feline medicine and surgery 2010;12(8):577-83.
2009: Sylvie Rottey; Bieke Van Den Bossche; Guido Slegers; Simon Van Belle; Christophe Van De Wiele
Influence of chemotherapy on the biodistribution of [99mTc]hydrazinonicotinamide annexin V in cancer patients.
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutical Chemistry and Biology 2009;53(2):127-32.
2008: Mario De Decker; Klaus Bacher; Hubert Thierens; Guido Slegers; Rudi A Dierckx; Filip De Vos
In vitro and in vivo evaluation of direct rhenium-188-labeled anti-CD52 monoclonal antibody alemtuzumab for radioimmunotherapy of B-cell chronic lymphocytic leukemia.
Nuclear medicine and biology 2008;35(5):599-604.
2008: Veerle Kersemans; Valentijn G.L.P. Vergote; Virginie de Gelder; Indira Madani; Hubert Thierens; Wilfried De Neve; John Mertens; Guido Slegers; Christian Burvenich; Kathelijne Peremans; Bart De Spiegeleer
The use of [123I]-2-iodo-L-phenylalanine as an early radiotherapy evaluation tool: in vitro R1M rabdomyosarcoma cell and in vivo mouse experiments.
Cancer biotherapy & radiopharmaceuticals 2008;23(2):192-201.
2008: Valentijn G.L.P. Vergote; Bram Baert; Eva Vandermeulen; Kathelijne Peremans; Henri van Bree; Guido Slegers; Christian Burvenich; Bart De Spiegeleer
LC-UV/MS characterization and DOE optimization of the iodinated peptide obestatin.
Journal of pharmaceutical and biomedical analysis 2008;46(1):127-36.
2008: David Loose; Hubert Vermeersch; Filip De Vos; Philippe Deron; Guido Slegers; Christophe Van De Wiele
Prognostic value of 99mTc-HYNIC annexin-V imaging in squamous cell carcinoma of the head and neck.
European journal of nuclear medicine and molecular imaging 2008;35(1):47-52.
2007: Bram Baert; Eric Deconinck; Mireille Van Gele; Marian Slodicka; Paul Stoppie; Samuel Bodé; Guido Slegers; Yvan Vander Heyden; Julien Lambert; Johan Beetens; Bart De Spiegeleer
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Bioorganic & medicinal chemistry 2007;15(22):6943-55.
2007: Kathelijne Peremans; Veerle Kersemans; Tiziana Liuti; E Vandermeulen; Bart Cornelissen; Ingrid M Gielen; Bart De Spiegeleer; John Mertens; Christian Burvenich; Guido Slegers
Use of [123I]-2-iodo-L-phenylalanine as a tumor imaging agent in two dogs with synovial cell sarcoma.
Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association 2007;48(5):471-4.
2007: Ingeborg Goethals; Myriam Vervaet; Kurt Audenaert; Filip Jacobs; Hamphrey Ham; Christophe Van De Wiele; Marleen Vandecapelle; Guido Slegers; Rudi Dierckx; Cees Van Heeringen
Differences of cortical 5-HT2A receptor binding index with SPECT in subtypes of anorexia nervosa: relationship with personality traits?
Journal of psychiatric research 2007;41(5):455-8.
2007: Samuel Bodé; Bram Baert; M Vangele; Julien Lambert; Christian Burvenich; Guido Slegers; Bart De Spiegeleer
Stability of the OECD model compound benzoic acid in receptor fluids of Franz diffusion cells.
Die Pharmazie 2007;62(6):470-1.
2007: Bart De Spiegeleer; Bram Baert; N Diericx; Dave Seghers; Francis Verpoort; Lieven Van Vooren; Christian Burvenich; Guido Slegers
Assessment of the solid-state composition of an active salicylanilide compound by FT-Raman spectroscopy.
Journal of pharmaceutical and biomedical analysis 2007;44(1):254-7.
2007: Valentijn G.L.P. Vergote; Samuel Bodé; Kathelijne Peremans; H Vanbree; Bram Baert; Guido Slegers; Christian Burvenich; Bart De Spiegeleer
Analysis of iodinated peptides by LC-DAD/ESI ion trap mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;850(1-2):213-20.
2007: Ingrid Burvenich; Steve Schoonooghe; Peter Blanckaert; Klaus Bacher; Liesbet Vervoort; Elisabeth Coene; Nico Mertens; Filip De Vos; Guido Slegers
Biodistribution and planar gamma camera imaging of (123)I- and (131)I-labeled F(ab')(2) and Fab fragments of monoclonal antibody 14C5 in nude mice bearing an A549 lung tumor.
Nuclear medicine and biology 2007;34(3):257-65.
2007: Patrice Pétillot; Christophe Lahorte; Elena Bonanno; Alberto Signore; Steve Lancel; Philippe MARCHETTI; Benoit Vallet; Guido Slegers; Remi Neviere
Annexin V detection of lipopolysaccharide-induced cardiac apoptosis.
Shock (Augusta, Ga.) 2007;27(1):69-74.
2006: Sylvie Rottey; Guido Slegers; Simon Van Belle; Ingeborg Goethals; Christophe Van De Wiele
Sequential 99mTc-hydrazinonicotinamide-annexin V imaging for predicting response to chemotherapy.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(11):1813-8.
2006: Bieke Lambert; Leo de Ridder; Filip De Vos; Guido Slegers; Virginie de Gelder; Christophe Van De Wiele; Hubert Thierens
Assessment of supra-additive effects of cytotoxic drugs and low dose rate irradiation in an in vitro model for hepatocellular carcinoma.
Canadian journal of physiology and pharmacology 2006;84(10):1021-8.
2006: Rien H Siaens; Vincent G H Eijsink; Gustav Vaaje-Kolstad; Katia Vandenbulcke; Bart Cornelissen; Claude Cuvelier; Rudi Dierckx; Guido Slegers
Synthesis and evaluation of a 99mTechnetium labeled chitin-binding protein as potential specific radioligand for the detection of fungal infections in mice.
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutical Chemistry and Biology 2006;50(3):155-66.
2006: Katia Vandenbulcke; Hubert Thierens; Filip De Vos; Jan Philippé; Fritz Offner; Ann Janssens; Christos Apostolidis; Alfred Morgenstern; Klaus Bacher; Virginie de Gelder; Rudi A Dierckx; Guido Slegers
In vitro screening for synergism of high-linear energy transfer 213Bi-radiotherapy with other therapeutic agents for the treatment of B-cell chronic lymphocytic leukemia.
Cancer biotherapy & radiopharmaceuticals 2006;21(4):364-72.
2006: Veerle Kersemans; Bart Cornelissen; Ken Kersemans; Matthias Bauwens; Rudi A Dierckx; Bart De Spiegeleer; John Mertens; Guido Slegers
123/125I-labelled 2-iodo-L: -phenylalanine and 2-iodo-D: -phenylalanine: comparative uptake in various tumour types and biodistribution in mice.
European journal of nuclear medicine and molecular imaging 2006;33(8):919-27.
2006: Veerle Kersemans; Ken Kersemans; Bart Cornelissen; Ludovicus Staelens; Bart De Spiegeleer; John Mertens; Guido Slegers
Optimization by experimental design of precursor synthesis and radiolabeling of 2-iodo-L-phenylalanine, a novel amino acid for tumor imaging.
Cancer biotherapy & radiopharmaceuticals 2006;21(3):235-42.
2006: Bart De Spiegeleer; E Wattyn; Guido Slegers; P Veys; G Derrieu; Lieven Van Vooren
Characterisation of a preservative system in an oily preparation.
Die Pharmazie 2006;61(6):545-51.
2006: Katia Vandenbulcke; Lada-Ivana Laenen Horvat; Martine De Mil; Guido Slegers; Hilde Beele
Evaluation of the antibacterial activity and toxicity of 2 new hydrogels: a pilot study.
The international journal of lower extremity wounds 2006;5(2):109-14.
2006: Ruth Oltenfreiter; Ludovicus Staelens; Veerle Kersemans; Bart Cornelissen; Francis Frankenne; Jean-Michel Foidart; Christophe Van De Wiele; Guido Slegers
Valine-based biphenylsulphonamide matrix metalloproteinase inhibitors as tumor imaging agents.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2006;64(6):677-85.
2006: Bart De Spiegeleer; E Wattyn; Guido Slegers; Paul Van der Meeren; K Vlaminck; Lieven Van Vooren
The importance of the cosolvent propylene glycol on the antimicrobial preservative efficacy of a pharmaceutical formulation by DOE-ruggedness testing.
Pharmaceutical development and technology 2006;11(3):275-84.
2006: Veerle Kersemans; Bart De Spiegeleer; John Mertens; Guido Slegers
Influence of sedation and data acquisition method on tracer uptake in animal models: [123I]-2-iodo-L-phenylalanine in pentobarbital-sedated tumor-bearing athymic mice.
Nuclear medicine and biology 2006;33(1):119-23.
2006: Veerle Kersemans; Bart Cornelissen; Ken Kersemans; Rudi A Dierckx; Bart De Spiegeleer; John Mertens; Guido Slegers
Comparative biodistribution study of the new tumor tracer [123I]-2-iodo-L-phenylalanine with [123I]-2-iodo-L-tyrosine.
Nuclear medicine and biology 2006;33(1):111-7.
2005: Ruth Oltenfreiter; Ludovicus Staelens; Soraya Labied; Veerle Kersemans; Francis Frankenne; Agnès Noël; Christophe Van De Wiele; Guido Slegers
Tryptophane-based biphenylsulfonamide matrix metalloproteinase inhibitors as tumor imaging agents.
Cancer biotherapy & radiopharmaceuticals 2005;20(6):639-47.
2005: Veerle Kersemans; Bart Cornelissen; Klaus Bacher; Ken Kersemans; Hubert Thierens; Rudi A Dierckx; Bart De Spiegeleer; Guido Slegers; John Mertens
In vivo evaluation and dosimetry of 123I-2-iodo-D-phenylalanine, a new potential tumor-specific tracer for SPECT, in an R1M rhabdomyosarcoma athymic mouse model.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46(12):2104-11.
2005: Stefanie Dedeurwaerdere; Bart Cornelissen; Koen Van Laere; Kristl Vonck; Eric Achten; Guido Slegers; Paul Boon
Small animal positron emission tomography during vagus nerve stimulation in rats: a pilot study.
Epilepsy research 2005;67(3):133-41.
2005: Ingrid Burvenich; Steve Schoonooghe; Bart Cornelissen; Peter Blanckaert; Elisabeth Coene; Claude Cuvelier; Nico Mertens; Guido Slegers
In vitro and in vivo targeting properties of iodine-123- or iodine-131-labeled monoclonal antibody 14C5 in a non-small cell lung cancer and colon carcinoma model.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(20):7288-96.
2005: Bart De Spiegeleer; Dave Seghers; R Wieme; J Schaubroeck; Francis Verpoort; Guido Slegers; Lieven Van Vooren
Determination of the relative amounts of three crystal forms of a benzimidazole drug in complex finished formulations by FT-Raman spectroscopy.
Journal of pharmaceutical and biomedical analysis 2005;39(1-2):275-80.
2005: Bart Cornelissen; Ruth Oltenfreiter; Veerle Kersemans; Ludovicus Staelens; Francis Frankenne; Jean-Michel Foidart; Guido Slegers
In vitro and in vivo evaluation of [123I]-VEGF165 as a potential tumor marker.
Nuclear medicine and biology 2005;32(5):431-6.
2005: Ruth Oltenfreiter; Ludovicus Staelens; Ulrik Hillaert; An Heremans; Agnès Noël; Francis Frankenne; Guido Slegers
Synthesis, radiosynthesis, in vitro and preliminary in vivo evaluation of biphenyl carboxylic and hydroxamic matrix metalloproteinase (MMP) inhibitors as potential tumor imaging agents.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2005;62(6):903-13.
2005: Peter Blanckaert; Ingrid Burvenich; Ludovicus Staelens; Rudi A Dierckx; Guido Slegers
Synthesis, radiosynthesis and in vivo evaluation in mice of [123I]-(4-fluorophenyl) {1-[2-(4-iodophenyl)ethyl]piperidin-4-yl}methanone for visualization of the 5-HT2A receptor with SPECT.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2005;62(5):737-43.
2005: Ludovicus Staelens; Ruth Oltenfreiter; Peter Blanckaert; Veerle Kersemans; Katia Vandenbulcke; Christophe Van De Wiele; Guido Slegers
In vivo evaluation of [(123)I]-3-(4-iodobenzyl)-1,2,3,4-tetrahydro-8-hydroxychromeno[3,4-c]pyridin-5-one: a presumed dopamine D4 receptor ligand for SPECT studies.
Nuclear medicine and biology 2005;32(3):293-9.
2005: Bart Cornelissen; Christophe Lahorte; Veerle Kersemans; Gabriela Capriotti; Elena Bonanno; Alberto Signore; Christophe Van De Wiele; Rudi A Dierckx; Guido Slegers
In vivo apoptosis detection with radioiodinated Annexin V in LoVo tumour-bearing mice following Tipifarnib (Zarnestra, R115777) farnesyltransferase inhibitor therapy.
Nuclear medicine and biology 2005;32(3):233-9.
2005: Bart Cornelissen; Veerle Kersemans; L Jans; Ludovicus Staelens; Ruth Oltenfreiter; Thomas Thonissen; Eric Achten; Guido Slegers
Comparison between 1 T MRI and non-MRI based volumetry in inoculated tumours in mice.
The British journal of radiology 2005;78(928):338-42.
2005: Veerle Kersemans; Bart Cornelissen; Ken Kersemans; Matthias Bauwens; Eric Achten; Rudi A Dierckx; John Mertens; Guido Slegers
In vivo characterization of 123/125I-2-iodo-L-phenylalanine in an R1M rhabdomyosarcoma athymic mouse model as a potential tumor tracer for SPECT.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46(3):532-9.
2005: Ludovicus Staelens; Ruth Oltenfreiter; Filip Dumont; Rikki N Waterhouse; Katia Vandenbulcke; Peter Blanckaert; Rudi A Dierckx; Guido Slegers
In vivo evaluation of [123I]-4-iodo-N-(4-(4-(2-methoxyphenyl)-piperazin-1-yl)butyl)-benzamide: a potential sigma receptor ligand for SPECT studies.
Nuclear medicine and biology 2005;32(2):193-200.
2005: Bart Cornelissen; Veerle Kersemans; Ingrid Burvenich; Ruth Oltenfreiter; Jean-Luc Vanderheyden; Otto Boerman; Christophe Vandewiele; Guido Slegers
Synthesis, biodistribution and effects of farnesyltransferase inhibitor therapy on tumour uptake in mice of 99mTc labelled epidermal growth factor.
Nuclear medicine communications 2005;26(2):147-53.
2004: Rien H Siaens; Huub J Rennen; Otto Boerman; Rudi Dierckx; Guido Slegers
Synthesis and comparison of 99mTc-enrofloxacin and 99mTc-ciprofloxacin.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(12):2088-94.
2004: Katia Vandenbulcke; Hubert Thierens; Fritz Offner; Ann Janssens; Virginie de Gelder; Klaus Bacher; Jan Philippé; Filip De Vos; Rudi Dierckx; Christos Apostolidis; Alfred Morgenstern; Guido Slegers
Importance of receptor density in alpha radioimmunotherapy in B cell malignancies: an in-vitro study.
Nuclear medicine communications 2004;25(11):1131-6.
2004: Ingeborg Goethals; Myriam Vervaet; Kurt Audenaert; Christophe Van De Wiele; Hamphrey Ham; Marleen Vandecapelle; Guido Slegers; Rudi Dierckx; Cees Van Heeringen
Comparison of cortical 5-HT2A receptor binding in bulimia nervosa patients and healthy volunteers.
The American journal of psychiatry 2004;161(10):1916-8.
2004: John Mertens; Veerle Kersemans; Matthias Bauwens; C Joos; Tony Lahoutte; Axel Bossuyt; Guido Slegers
Synthesis, radiosynthesis, and in vitro characterization of [125I]-2- iodo-L-phenylalanine in a R1M rhabdomyosarcoma cell model as a new potential tumor tracer for SPECT.
Nuclear medicine and biology 2004;31(6):739-46.
2004: Bart Cornelissen; Thomas Thonissen; Veerle Kersemans; Christophe Van De Wiele; Christophe Lahorte; Rudi A Dierckx; Guido Slegers
Influence of farnesyl transferase inhibitor treatment on epidermal growth factor receptor status.
Nuclear medicine and biology 2004;31(6):679-89.
2004: Rien H Siaens; Vincent G H Eijsink; Rudi Dierckx; Guido Slegers
(123)I-Labeled chitinase as specific radioligand for in vivo detection of fungal infections in mice.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(7):1209-16.
2004: Jan Courtyn; Bart Cornelissen; Ruth Oltenfreiter; Marleen Vandecapelle; Guido Slegers; Karel Strijckmans
Synthesis and assessment of [11C]acetylhomotaurine as an imaging agent for the study of the pharmacodynamic properties of acamprosate by positron emission tomography.
Nuclear medicine and biology 2004;31(5):649-54.
2004: Hubert Vermeersch; Kris Mervillie; Christophe Lahorte; David Loose; Rudi Andre Dierck; Neil Steinmetz; Claude Cuvelier; Guido Slegers; Christophe Van De Wiele
Relationship of 99mTc-HYNIC annexin V uptake to microvessel density, FasL and MMP-9 expression, and the number of tumour-infiltrating lymphocytes in head and neck carcinoma.
European journal of nuclear medicine and molecular imaging 2004;31(7):1016-21.
2004: Christophe Lahorte; Klaus Bacher; Ingrid Burvenich; Elisabeth Coene; Claude Cuvelier; Christian R De Potter; Hubert Thierens; Christophe Van De Wiele; Rudi A Dierckx; Guido Slegers
Radiolabeling, biodistribution, and dosimetry of (123)I-mAb 14C5: a new mAb for radioimmunodetection of tumor growth and metastasis in vivo.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(6):1065-73.
2004: Christophe Lahorte; Jean-Luc Vanderheyden; Neil Steinmetz; Christophe Van De Wiele; Rudi A Dierckx; Guido Slegers
Apoptosis-detecting radioligands: current state of the art and future perspectives.
European journal of nuclear medicine and molecular imaging 2004;31(6):887-919.
2004: Ruth Oltenfreiter; Ludovicus Staelens; Annabelle Lejeune; Filip Dumont; Francis Frankenne; Jean-Michel Foidart; Guido Slegers
New radioiodinated carboxylic and hydroxamic matrix metalloproteinase inhibitor tracers as potential tumor imaging agents.
Nuclear medicine and biology 2004;31(4):459-68.
2004: Hubert Vermeersch; David Loose; Christophe Lahorte; Kris Mervillie; Rudi Dierckx; Neil Steinmetz; Jean-Luc Vanderheyden; Claude Cuvelier; Guido Slegers; Christophe Van De Wiele
99mTc-HYNIC Annexin-V imaging of primary head and neck carcinoma.
Nuclear medicine communications 2004;25(3):259-63.
2004: Frederica Corsetti; Marco Chianelli; Bart Cornelissen; Christophe Van De Wiele; Calogero D'Alessandria; Guido Slegers; Stephen J Mather; Umberto Di Mario; Sebastiano Filetti; Francesco Scopinaro; Alberto Signore
Radioiodinated recombinant human TSH: a novel radiopharmaceutical for thyroid cancer metastases detection.
Cancer biotherapy & radiopharmaceuticals 2004;19(1):57-63.
2004: Bieke Lambert; Leo de Ridder; Guido Slegers; Virginie de Gelder; Rudi A Dierckx; Hubert Thierens
Screening for supra-additive effects of cytotoxic drugs and gamma irradiation in an in vitro model for hepatocellular carcinoma.
Canadian journal of physiology and pharmacology 2004;82(2):146-52.
2003: Kathelijne Peremans; Kurt Audenaert; Frank Coopman; Peter Blanckaert; Filip Jacobs; Andreas Otte; Francis Verschooten; Henri van Bree; Kees van Heeringen; John Mertens; Guido Slegers; Rudi Dierckx
Estimates of regional cerebral blood flow and 5-HT2A receptor density in impulsive, aggressive dogs with 99mTc-ECD and 123I-5-I-R91150.
European journal of nuclear medicine and molecular imaging 2003;30(11):1538-46.
2003: Katia Vandenbulcke; Filip De Vos; Fritz Offner; Jan Philippé; Christos Apostolidis; Roger Molinet; Tuomo K Nikula; Klaus Bacher; Virginie de Gelder; Anne Vral; Christophe Lahorte; Hubert Thierens; Rudi A Dierckx; Guido Slegers
In vitro evaluation of 213Bi-rituximab versus external gamma irradiation for the treatment of B-CLL patients: relative biological efficacy with respect to apoptosis induction and chromosomal damage.
European journal of nuclear medicine and molecular imaging 2003;30(10):1357-64.
2003: Christophe Van De Wiele; Christophe Lahorte; Hubert Vermeersch; David Loose; Kris Mervillie; Neil Steinmetz; Jean-Luc Vanderheyden; Claude Cuvelier; Guido Slegers; Rudi Andre Dierck
Quantitative tumor apoptosis imaging using technetium-99m-HYNIC annexin V single photon emission computed tomography.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(18):3483-7.
2003: Christophe Lahorte; Christophe Van De Wiele; Klaus Bacher; Bieke Van Den Bossche; Hubert Thierens; Simon Van Belle; Guido Slegers; Rudi A Dierckx
Biodistribution and dosimetry study of 123I-rh-annexin V in mice and humans.
Nuclear medicine communications 2003;24(8):871-80.
2003: Jan Versijpt; Koen Van Laere; Filip Dumont; Danny Decoo; Marleen Vandecapelle; Patrick Santens; Ingeborg Goethals; Kurt Audenaert; Guido Slegers; Rudi A Dierckx; Jakob Korf
Imaging of the 5-HT2A system: age-, gender-, and Alzheimer's disease-related findings.
Neurobiology of aging 2003;24(4):553-61.
2003: Kathelijne Peremans; Kurt Audenaert; Frank Coopman; Filip Jacobs; Filip Dumont; Guido Slegers; Francis Verschooten; Henri van Bree; John Mertens; Rudi Dierckx
Regional binding index of the radiolabeled selective 5-HT2A antagonist 123I-5-I-R91150 in the normal canine brain imaged with single photon emission computed tomography.
Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association 2003;44(3):344-51.
2003: Jan C Debruyne; Jan Versijpt; Koen Van Laere; Filip De Vos; J Keppens; Karel Strijckmans; Eric Achten; Guido Slegers; Rudi A Dierckx; Jakob Korf; Jacques de Reuck
PET visualization of microglia in multiple sclerosis patients using [11C]PK11195.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2003;10(3):257-64.
2003: Cees Van Heeringen; Kurt Audenaert; Koen Van Laere; Filip Dumont; Guido Slegers; John Mertens; Rudi A Dierckx
Prefrontal 5-HT2a receptor binding index, hopelessness and personality characteristics in attempted suicide.
Journal of affective disorders 2003;74(2):149-58.
2003: Kurt Audenaert; Koen Van Laere; Filip Dumont; Myriam Vervaet; Ingeborg Goethals; Guido Slegers; John Mertens; Cees Van Heeringen; Rudi A Dierckx
Decreased 5-HT2a receptor binding in patients with anorexia nervosa.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003;44(2):163-9.
2003: Jan Versijpt; Koen Van Laere; Rudi A Dierckx; Filip Dumont; P P De Deyn; Guido Slegers; Jakob Korf
Scintigraphic visualization of inflammation in neurodegenerative disorders.
Nuclear medicine communications 2003;24(2):209-21.
2003: Jan Versijpt; Filip Dumont; Koen Van Laere; Danny Decoo; Patrick Santens; Kurt Audenaert; Eric Achten; Guido Slegers; Rudi A Dierckx; Jakob Korf
Assessment of neuroinflammation and microglial activation in Alzheimer's disease with radiolabelled PK11195 and single photon emission computed tomography. A pilot study.
European neurology 2003;50(1):39-47.
2003: Christophe Van De Wiele; Christophe Lahorte; Wim Oyen; Otto Boerman; Ingeborg Goethals; Guido Slegers; Rudi A Dierckx
Nuclear medicine imaging to predict response to radiotherapy: a review.
International journal of radiation oncology, biology, physics 2003;55(1):5-15.
2002: Kathelijne Peremans; Kurt Audenaert; Peter Blanckaert; Filip Jacobs; Frank Coopman; Francis Verschooten; Henri van Bree; Cees Van Heeringen; John Mertens; Guido Slegers; Rudi Dierckx
Effects of aging on brain perfusion and serotonin-2A receptor binding in the normal canine brain measured with single photon emission tomography.
Progress in neuro-psychopharmacology & biological psychiatry 2002;26(7-8):1393-404.
2002: Kathelijne Peremans; Kurt Audenaert; Filip Jacobs; Filip Dumont; Filip De Vos; Christophe Van De Wiele; Marleen Vandecapelle; Henri van Bree; Francis Verschooten; Guido Slegers; John Mertens; Rudi Dierckx
Biodistribution and displacement studies of the selective 5-HT2A receptor antagonist 123I-5-I-R91150 in the normal dog.
Nuclear medicine communications 2002;23(10):1019-27.
2002: Jan C Debruyne; Koen Van Laere; Jan Versijpt; Filip De Vos; Johan Keppens Eng; Karel Strijckmans; Patrick Santens; Eric Achten; Guido Slegers; Jakob Korf; Rudi A Dierckx; Jacques de Reuck
Semiquantification of the peripheral-type benzodiazepine ligand [11C]PK11195 in normal human brain and application in multiple sclerosis patients.
Acta neurologica Belgica 2002;102(3):127-35.
2002: Lieven Van Vooren; Bart De Spiegeleer; Thomas Thonissen; Philippe Joye; Joost Van Durme; Guido Slegers
Statistical analysis of tablet breakability methods.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2002;5(2):190-8.
2002: Christophe Van De Wiele; Ruth Oltenfreiter; Olivier De Winter; Alberto Signore; Guido Slegers; Rudi A Dierckx
Tumour angiogenesis pathways: related clinical issues and implications for nuclear medicine imaging.
European journal of nuclear medicine and molecular imaging 2002;29(5):699-709.
2001: Christophe Van De Wiele; Veronique Cocquyt; R VandenBroecke; Filip De Vos; Simon Van Belle; Karl Dhaene; Guido Slegers; Rudi A Dierckx
Iodine-labeled tamoxifen uptake in primary human breast carcinoma.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2001;42(12):1818-20.
2001: Christophe Van De Wiele; Filip Dumont; Rudi A Dierckx; SH Peers; JR Thornback; Guido Slegers; Hubert Thierens
Biodistribution and dosimetry of (99m)Tc-RP527, a gastrin-releasing peptide (GRP) agonist for the visualization of GRP receptor-expressing malignancies.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2001;42(11):1722-7.
2001: Marleen Vandecapelle; Filip De Vos; H Vermeirsch; G De Ley; Kurt Audenaert; D Leysen; Rudi A Dierckx; Guido Slegers
In vivo evaluation of 4-[123I]iodo-N-[2[4-(6-trifluoromethyl-2-pyridinyl)-1-piperazinyl]ethyl]benzamide, a potential SPECT radioligand for the 5-HT1A receptor.
Nuclear medicine and biology 2001;28(6):639-43.
2001: Jan Versijpt; Danny Decoo; Koen Van Laere; Eric Achten; Kurt Audenaert; Yves D'Asseler; Guido Slegers; Rudi A Dierckx; Jakob Korf
57Co SPECT, 99mTc-ECD SPECT, MRI and neuropsychological testing in senile dementia of the Alzheimer type.
Nuclear medicine communications 2001;22(6):713-9.
2001: Frederic De Winter; Christophe Van De Wiele; Filip Dumont; J Van Durme; K Solanki; K Britton; Guido Slegers; Rudi A Dierckx; Hubert Thierens
Biodistribution and dosimetry of 99mTc-ciprofloxacin, a promising agent for the diagnosis of bacterial infection.
European journal of nuclear medicine 2001;28(5):570-4.
2001: Filip De Vos; Christophe Van De Wiele; Marleen Vandecapelle; Rudi A Dierckx; Guido Slegers
High performance liquid chromatographic determination of 123-I labeled tamoxifen metabolites in human plasma.
Nuclear medicine and biology 2001;28(3):335-8.
2001: Kurt Audenaert; Koen Van Laere; Filip Dumont; Guido Slegers; John Mertens; Cees Van Heeringen; Rudi A Dierckx
Decreased frontal serotonin 5-HT 2a receptor binding index in deliberate self-harm patients.
European journal of nuclear medicine 2001;28(2):175-82.
2001: Christophe Van De Wiele; Filip Dumont; Simon Van Belle; Guido Slegers; SH Peers; Rudi A Dierckx
Is there a role for agonist gastrin-releasing peptide receptor radioligands in tumour imaging?
Nuclear medicine communications 2001;22(1):5-15.
2001: Christophe Lahorte; Guido Slegers; Jan Philippé; Christophe Van De Wiele; Rudi A Dierckx
Synthesis and in vitro evaluation of 123I-labelled human recombinant annexin V.
Biomolecular engineering 2001;17(2):51-3.
2001: Patrick Santens; Jan L De Bleecker; Peter L M Goethals; Karel Strijckmans; Ignace Lemahieu; Guido Slegers; Rudi Dierckx; Jacques de Reuck
Differential regional cerebral uptake of (18)F-fluoro-2-deoxy-D-glucose in Alzheimer's disease and frontotemporal dementia at initial diagnosis.
European neurology 2001;45(1):19-27.
2000: Filip De Vos; Patrick Santens; H Vermeirsch; I Dewolf; Filip Dumont; Guido Slegers; Rudi A Dierckx
Pharmacological evaluation of [11C]donepezil as a tracer for visualization of acetylcholinesterase by PET.
Nuclear medicine and biology 2000;27(8):745-7.
2000: Christophe Van De Wiele; Filip Dumont; R Vanden Broecke; W Oosterlinck; Veronique Cocquyt; Rudolphe F Serreyn; SH Peers; JR Thornback; Guido Slegers; Rudi A Dierckx
Technetium-99m RP527, a GRP analogue for visualisation of GRP receptor-expressing malignancies: a feasibility study.
European journal of nuclear medicine 2000;27(11):1694-9.
2000: Johan De Sutter; Christophe Lahorte; Yves Taeymans; Rudi Dierckx; Guido Slegers
Cell death in myocardial infarction.
Lancet 2000;356(9239):1439-40.
2000: Christophe Van De Wiele; Filip De Vos; Guido Slegers; Simon Van Belle; Rudi A Dierckx
Radiolabeled estradiol derivatives to predict response to hormonal treatment in breast cancer: a review.
European journal of nuclear medicine 2000;27(9):1421-33.
2000: Jan Versijpt; Filip Dumont; Hubert Thierens; H Jansen; Filip De Vos; Guido Slegers; Patrick Santens; Rudi A Dierckx; Jakob Korf
Biodistribution and dosimetry of [123I]iodo-PK 11195: a potential agent for SPET imaging of the peripheral benzodiazepine receptor.
European journal of nuclear medicine 2000;27(9):1326-33.
1999: Filip De Vos; Filip Dumont; Patrick Santens; Guido Slegers; Rudi Dierckx; J De Reuck
High-performance liquid chromatographic determination of [11C]1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinoline carboxamide in mouse plasma and tissue and in human plasma.
Journal of chromatography. B, Biomedical sciences and applications 1999;736(1-2):61-6.
1999: Christophe Van De Wiele; Filip De Vos; Johan De Sutter; Filip Dumont; Guido Slegers; Rudi A Dierckx; Hubert Thierens
Biodistribution and dosimetry of (iodine-123)-iodomethyl-N, N-diethyltamoxifen, an (anti)oestrogen receptor radioligand.
European journal of nuclear medicine 1999;26(10):1259-64.
1999: Patrick Santens; Filip De Vos; D Bouden; Guido Slegers; Ignace Lemahieu; P Boon; Jacques de Reuck
The pharmacokinetics of [11C]methoxy-norchloroprogabidic acid, a potential PET tracer for GABA receptors in the brain.
Nuclear medicine and biology 1999;26(3):323-5.
1999: Filip Dumont; Filip De Vos; Jan Versijpt; H M Jansen; Jakob Korf; Rudi A Dierckx; Guido Slegers
In vivo evaluation in mice and metabolism in blood of human volunteers of [123I]iodo-PK11195: a possible single-photon emission tomography tracer for visualization of inflammation.
European journal of nuclear medicine 1999;26(3):194-200.
1998: Patrick Santens; Filip De Vos; Hubert Thierens; Danny Decoo; Guido Slegers; Rudi A Dierckx; Jacques de Reuck
Biodistribution and dosimetry of carbon-11-methoxyprogabidic acid, a possible ligand for GABA-receptors in the brain.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1998;39(2):307-10.
1997: F Dumont; Guido Slegers
Synthesis and in vivo evaluation of 7-chloro-5-[123I]iodo-4-oxo-1,4-dihydroquinoline-2-carboxylic acid.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 1997;48(9):1173-7.
1991: G S Mannens; Guido Slegers; Peter L M Goethals; A Claeys
Enzymatic synthesis of 11C-N-acetyl-D-glucosamine.
Acta radiologica. Supplementum 1991;376():106.
1990: G Mannens; Guido Slegers
Immobilization of acetyl-CoA:arylamine N-acetyltransferase and the preparation of an enzyme reactor for the synthesis of N-[11C]acetylserotonin.
Biochimica et biophysica acta 1990;1038(1):68-73.
1990: G Mannens; Guido Slegers; A Claeys
Assay for acetyl-CoA:arylamine N-acetyltransferase by high-performance liquid chromatography applied to serotonin N-acetylation.
Biochimica et biophysica acta 1990;1037(1):1-6.
1990: Peter L M Goethals; M Coene; Guido Slegers; D Vogelaers; J Everaert; Ignace Lemahieu; F Colardyn; G R Heyndrickx
Production of carrier-free 66Ga and labeling of antimyosin antibody for positron imaging of acute myocardial infarction.
European journal of nuclear medicine 1990;16(4-6):237-40.
1989: E Poupeye; R E Counsell; A De Leenheer; Guido Slegers; Peter L M Goethals
Synthesis of 11C-labelled thymidine for tumor visualization using positron emission tomography.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1989;40(1):57-61.
1988: B De Spiegeleer; Peter L M Goethals; Guido Slegers; E Gillis; W Van den Bossche; P De Moerloose
Synthesis and radiopharmaceutical preparation of (ethylenediamine) (1-carbon-11-malonate) platinum(II) for PET studies.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1988;29(6):1107-13.
1988: G Mannens; Guido Slegers; R Lambrecht; A Claeys
Immobilization of acetylcoenzyme A synthetase and the preparation of an enzyme reactor for the synthesis of [11C]acetylcoenzyme A.
Biochimica et biophysica acta 1988;959(3):214-9.
1988: Peter L M Goethals; M Coene; Guido Slegers; P Agon; J Deman; K Schelstraete
Cyclotron production of carrier-free 66Ga as a positron emitting label of albumin colloids for clinical use.
European journal of nuclear medicine 1988;14(3):152-4.
1987: K De Vis; K Schelstraete; J Deman; F L Vermeulen; J Sambre; Peter L M Goethals; Dirk Van Haver; Guido Slegers; C Vandecasteele; A De Schryver
Clinical comparison of 11C-ACPC (aminocyclopentane carboxylic acid) and 13N-ammonia as tumour tracers.
Acta oncologica (Stockholm, Sweden) 1987;26(2):105-11.
1986: B De Spiegeleer; G Mannens; Guido Slegers; W Van den Bossche; A Claeys
Direct assay for phosphotransacetylase and acetyl-coenzyme A carboxylase by high-performance liquid chromatography.
Analytical biochemistry 1986;158(1):195-200.
1986: B De Spiegeleer; Guido Slegers; C Vandecasteele; W Van den Bossche; K Schelstraete; A Claeys; P De Moerloose
Microscale synthesis of nitrogen-13-labeled cisplatin.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1986;27(3):399-403.
1986: B De Spiegeleer; Guido Slegers; W Van den Bossche; P De Moerloose
[Antitumor activity of cisplatin and its derivatives].
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 1986;48(3):142-62.
1985: K Schelstraete; J Deman; F L Vermeulen; K Strijckmans; C Vandecasteele; Guido Slegers; A De Schryver
Kinetics of 13N-ammonia incorporation in human tumours.
Nuclear medicine communications 1985;6(8):461-70.
1985: T Vandewalle; C Vandecasteele; F De Guchteneire; L Meulewaeter; Dirk Van Haver; H Denutte; Peter L M Goethals; Guido Slegers
Fully automatic, microprocessor-controlled system for the production of 11CO2, 11CH3I and 11C-labeled radiopharmaceuticals.
The International journal of applied radiation and isotopes 1985;36(6):469-74.
1984: B De Spiegeleer; Guido Slegers; W Van den Bossche; P De Moerloose
Quantitative analysis of cis-dichlorodiammineplatinum(II) by high-performance thin-layer chromatography.
Journal of chromatography 1984;315():481-7.
1984: Guido Slegers; R H Lambrecht; T Vandewalle; L Meulewaeter; C Vandecasteele
Enzymatic synthesis of C-11 formaldehyde: concise communication.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1984;25(3):338-42.
1982: K Schelstraete; M Simons; J Deman; F L Vermeulen; Guido Slegers; C Vandecasteele; Peter L M Goethals; A De Schryver
Uptake of 13N-ammonia by human tumours as studied by positron emission tomography.
The British journal of radiology 1982;55(659):797-804.