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Stephen Sligar

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TOP 3
Michael Gregory; Piotr J Mak; Stephen G Sligar; James R Kincaid
Differential Hydrogen Bonding in Human CYP17 Dictates Hydroxylation versus Lyase Chemistry.
Michael T Marty; William L Klein; Kyle C Wilcox; Stephen G Sligar
Nanodisc-solubilized membrane protein library reflects the membrane proteome.
Courtney D Kuhnline Sloan; Michael T Marty; Stephen G Sligar; Ryan C Bailey
Interfacing lipid bilayer nanodiscs and silicon photonic sensor arrays for multiplexed protein-lipid and protein-membrane protein interaction screening.

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All Publications

2013: Michael Gregory; Piotr J Mak; Stephen G Sligar; James R Kincaid
Differential Hydrogen Bonding in Human CYP17 Dictates Hydroxylation versus Lyase Chemistry.
Angewandte Chemie (International ed. in English) 2013;52(20):5342-5.
2013: Michael T Marty; William L Klein; Kyle C Wilcox; Stephen G Sligar
Nanodisc-solubilized membrane protein library reflects the membrane proteome.
Analytical and bioanalytical chemistry 2013;405(12):4009-16.
2013: Courtney D Kuhnline Sloan; Michael T Marty; Stephen G Sligar; Ryan C Bailey
Interfacing lipid bilayer nanodiscs and silicon photonic sensor arrays for multiplexed protein-lipid and protein-membrane protein interaction screening.
Analytical chemistry 2013;85(5):2970-6.
2013: Yelena V Grinkova; Mark A McLean; Ilia G Denisov; Stephen G Sligar
Oxidase uncoupling in heme monooxygenases: human cytochrome P450 CYP3A4 in Nanodiscs.
Biochemical and biophysical research communications 2013;430(4):1223-7.
2013: A Luthra; Ilia Denisov; M Gregory; Yelena V Grinkova; Stephen G Sligar
Nanodiscs in the studies of membrane-bound cytochrome P450 enzymes.
Methods in molecular biology (Clifton, N.J.) 2013;987():115-27.
2013: Mary A Schuler; Ilia G Denisov; Stephen G Sligar
Nanodiscs as a new tool to examine lipid-protein interactions.
Methods in molecular biology (Clifton, N.J.) 2013;974():415-33.
2012: Michael T Marty; Robert E Blankenship; Weidong Cui; Michael L Gross; Hao Zhang; Stephen G Sligar
Native mass spectrometry characterization of intact nanodisc lipoprotein complexes.
Analytical chemistry 2012;84(21):8957-60.
2012: Michael T Marty; Ryan C Bailey; Courtney D Kuhnline Sloan; Stephen G Sligar
Nonlinear analyte concentration gradients for one-step kinetic analysis employing optical microring resonators.
Analytical chemistry 2012;84(13):5556-64.
2012: James H Morrissey; Stephen G Sligar; Emadeddin Emadeddin Tajkhorshid; Chad M Rienstra
Tissue factor/factor VIIa complex: role of the membrane surface.
Thrombosis research 2012;129 Suppl 2():S8-10.
2012: Ilia G Denisov; Stephen G Sligar
A novel type of allosteric regulation: functional cooperativity in monomeric proteins.
Archives of biochemistry and biophysics 2012;519(2):91-102.
2012: Kush Dalal; Catherine S Chan; Stephen G Sligar; Franck Duong
Two copies of the SecY channel and acidic lipids are necessary to activate the SecA translocation ATPase.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(11):4104-9.
2012: Linda Näsvik Öjemyr; Stephen G Sligar; Christoph von Ballmoos; Robert B Gennis; Peter Brzezinski
Reconstitution of respiratory oxidases in membrane nanodiscs for investigation of proton-coupled electron transfer.
FEBS letters 2012;586(5):640-5.
2012: I G Denisov; A Y Shih; Stephen G Sligar
Structural differences between soluble and membrane bound cytochrome P450s.
Journal of inorganic biochemistry 2012;108():150-8.
2012: Ilia Denisov; Yelena V Grinkova; Stephen G Sligar
Cryoradiolysis and cryospectroscopy for studies of heme-oxygen intermediates in cytochromes p450.
Methods in molecular biology (Clifton, N.J.) 2012;875():375-91.
2012: Michael T Marty; Aditi Das; Stephen G Sligar
Ultra-thin layer MALDI mass spectrometry of membrane proteins in nanodiscs.
Analytical and bioanalytical chemistry 2012;402(2):721-9.
2011: Brett R Goldsmith; Timothy H Bayburt; Joseph G Brand; Ana Castro; Bohdana M Discher; Alan Gelperin; Ryan A Jones; Jesusa Josue; Samuel M Khamis; Mitchell B Lerner; Charles W Luetje; Joseph J Mitala; Paul A Rhodes; Stephen G Sligar; A T Charlie Johnson
Biomimetic chemical sensors using nanoelectronic readout of olfactory receptor proteins.
ACS nano 2011;5(7):5408-16.
2011: Abhinav Luthra; Ilia G Denisov; Stephen G Sligar
Temperature derivative spectroscopy to monitor the autoxidation decay of cytochromes P450.
Analytical chemistry 2011;83(13):5394-9.
2011: Venugopal Karunakaran; Ilia Denisov; Stephen G Sligar; Paul M Champion
Investigation of the low frequency dynamics of heme proteins: native and mutant cytochrome P450(cam) and redox partner complexes.
The journal of physical chemistry. B 2011;115(18):5665-77.
2011: Abhinav Luthra; Ilia Denisov; Stephen G Sligar
Spectroscopic features of cytochrome P450 reaction intermediates.
Archives of biochemistry and biophysics 2011;507(1):26-35.
2011: Daniel J Frank; Ilia Denisov; Stephen G Sligar
Analysis of heterotropic cooperativity in cytochrome P450 3A4 using alpha-naphthoflavone and testosterone.
The Journal of biological chemistry 2011;286(7):5540-5.
2011: Piotr J Mak; Ilia Denisov; Yelena V Grinkova; Stephen G Sligar; James R Kincaid
Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450.
Journal of the American Chemical Society 2011;133(5):1357-66.
2011: Timothy H Bayburt; Sergey A Vishnivetskiy; Mark A McLean; Takefumi Morizumi; Chih-Chin Huang; John J G Tesmer; Oliver P Ernst; Stephen G Sligar; Vsevolod V Gurevich
Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding.
The Journal of biological chemistry 2011;286(2):1420-8.
2011: Ilia G Denisov; Stephen G Sligar
Cytochromes P450 in nanodiscs.
Biochimica et biophysica acta 2011;1814(1):223-9.
2010: Stephen G Sligar
Chemistry. Glimpsing the critical intermediate in cytochrome P450 oxidations.
Science (New York, N.Y.) 2010;330(6006):924-5.
2010: Aleksandra Kijac; Amy Y Shih; Andrew J Nieuwkoop; Klaus Schulten; Stephen G Sligar; Chad M Rienstra
Lipid-protein correlations in nanoscale phospholipid bilayers determined by solid-state nuclear magnetic resonance.
Biochemistry 2010;49(43):9190-8.
2010: Moon-Ho Ham; Jong Hyun Choi; Ardemis A Boghossian; Esther S Jeng; Rachel A Graff; Daniel A Heller; Alice C Chang; Aidas Mattis; Timothy H Bayburt; Yelena V Grinkova; Adam S Zeiger; Krystyn J Van Vliet; Erik K Hobbie; Stephen G Sligar; Colin A Wraight; Michael Strano
Photoelectrochemical complexes for solar energy conversion that chemically and autonomously regenerate.
Nature chemistry 2010;2(11):929-36.
2010: Yelena V Grinkova; Ilia G Denisov; Stephen G Sligar
Engineering extended membrane scaffold proteins for self-assembly of soluble nanoscale lipid bilayers.
Protein engineering, design & selection : PEDS 2010;23(11):843-8.
2010: Soo-Hyun Tark; Aditi Das; Stephen G Sligar; Vinayak P Dravid
Nanomechanical detection of cholera toxin using microcantilevers functionalized with ganglioside nanodiscs.
Nanotechnology 2010;21(43):435502.
2010: Nicholas Skar-Gislinge; Jens Bæk Simonsen; Kell Mortensen; Robert Feidenhans'l; Stephen G Sligar; Birger Lindberg Møller; Thomas Bjørnholm; Lise Arleth
Elliptical structure of phospholipid bilayer nanodiscs encapsulated by scaffold proteins: casting the roles of the lipids and the protein.
Journal of the American Chemical Society 2010;132(39):13713-22.
2010: Virginie Früh; Yunpeng Zhou; Dan Chen; Caroline Loch; Eiso Ab; Yelena N Grinkova; Herman Verheij; Stephen G Sligar; John H Bushweller; Gregg Siegal
Application of fragment-based drug discovery to membrane proteins: identification of ligands of the integral membrane enzyme DsbB.
Chemistry & biology 2010;17(8):881-91.
2010: Yelena V Grinkova; Ilia Denisov; Stephen G Sligar
Functional reconstitution of monomeric CYP3A4 with multiple cytochrome P450 reductase molecules in Nanodiscs.
Biochemical and biophysical research communications 2010;398(2):194-8.
2010: Carsten Grashoff; Brenton D Hoffman; Michael D Brenner; Ruobo Zhou; Maddy Parsons; Michael T Yang; Mark A McLean; Stephen G Sligar; Christopher S Chen; Taekjip Ha; Martin A Schwartz
Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics.
Nature 2010;466(7303):263-6.
2010: Timothy H Bayburt; Stephen G Sligar
Membrane protein assembly into Nanodiscs.
FEBS letters 2010;584(9):1721-7.
2010: Dmitri R Davydov; Elena Sineva; Srinivas Sistla; Nadezhda Y Davydova; Daniel J Frank; Stephen G Sligar; James Halpert
Electron transfer in the complex of membrane-bound human cytochrome P450 3A4 with the flavin domain of P450BM-3: the effect of oligomerization of the heme protein and intermittent modulation of the spin equilibrium.
Biochimica et biophysica acta 2010;1797(3):378-90.
2010: Feng Ye; Guiqing Hu; Dianne Taylor; Boris Ratnikov; Andrey A Bobkov; Mark A McLean; Stephen G Sligar; Kenneth A Taylor; Mark H Ginsberg
Recreation of the terminal events in physiological integrin activation.
The Journal of cell biology 2010;188(1):157-73.
2009: Aditi Das; Stephen G Sligar
Modulation of the cytochrome P450 reductase redox potential by the phospholipid bilayer.
Biochemistry 2009;48(51):12104-12.
2009: Ilia G Denisov; Daniel J Frank; Stephen G Sligar
Cooperative properties of cytochromes P450.
Pharmacology & therapeutics 2009;124(2):151-67.
2009: Amy Y Shih; Stephen G Sligar; Klaus Schulten
Maturation of high-density lipoproteins.
Journal of the Royal Society, Interface / the Royal Society 2009;6(39):863-71.
2009: Stephanie L Gantt; Ilia Denisov; Yelena V Grinkova; Stephen G Sligar
The critical iron-oxygen intermediate in human aromatase.
Biochemical and biophysical research communications 2009;387(1):169-73.
2009: Daniel J Frank; Ilia Denisov; Stephen G Sligar
Mixing apples and oranges: Analysis of heterotropic cooperativity in cytochrome P450 3A4.
Archives of biochemistry and biophysics 2009;488(2):146-52.
2009: James Morrissey; Vincent Pureza; Rebecca L Davis-Harrison; Stephen G Sligar; Chad M Rienstra; A Z Kijac; Y Z Ohkubo; Emadeddin Emadeddin Tajkhorshid
Protein-membrane interactions: blood clotting on nanoscale bilayers.
Journal of thrombosis and haemostasis : JTH 2009;7 Suppl 1():169-72.
2009: Aditi Das; Jing Zhao; George C Schatz; Stephen G Sligar; Richard P Van Duyne
Screening of type I and II drug binding to human cytochrome P450-3A4 in nanodiscs by localized surface plasmon resonance spectroscopy.
Analytical chemistry 2009;81(10):3754-9.
2009: Kush Dalal; Nham Nguyen; Meriem Alami; Jennifer Tan; Trevor F Moraes; Woo Cheol Lee; Robert Maurus; Stephen G Sligar; Gary D Brayer; Franck Duong
Structure, binding, and activity of Syd, a SecY-interacting protein.
The Journal of biological chemistry 2009;284(12):7897-902.
2009: Mark A McLean; Zenon Rajfur; Zaozao Chen; David Humphrey; Bing Yang; Stephen G Sligar; Ken Jacobson
Mechanism of chromophore assisted laser inactivation employing fluorescent proteins.
Analytical chemistry 2009;81(5):1755-61.
2009: T K Ritchie; Yelena V Grinkova; T H Bayburt; Ilia Denisov; J K Zolnerciks; William M Atkins; Stephen G Sligar
Chapter 11 - Reconstitution of membrane proteins in phospholipid bilayer nanodiscs.
Methods in enzymology 2009;464():211-31.
2008: Ilia Denisov; Piotr J Mak; Thomas M Makris; Stephen G Sligar; James R Kincaid
Resonance Raman characterization of the peroxo and hydroperoxo intermediates in cytochrome P450.
The journal of physical chemistry. A 2008;112(50):13172-9.
2008: Huiying Li; Aditi Das; Hiruy Sibhatu; Joumana Jamal; Stephen G Sligar; Thomas L Poulos
Exploring the electron transfer properties of neuronal nitric-oxide synthase by reversal of the FMN redox potential.
The Journal of biological chemistry 2008;283(50):34762-72.
2008: Edgar D Goluch; Andrew W Shaw; Stephen G Sligar; Chang Liu
Microfluidic patterning of nanodisc lipid bilayers and multiplexed analysis of protein interaction.
Lab on a chip 2008;8(10):1723-8.
2008: Jonas Borch; Federico Torta; Stephen G Sligar; Peter Roepstorff
Nanodiscs for immobilization of lipid bilayers and membrane receptors: kinetic analysis of cholera toxin binding to a glycolipid receptor.
Analytical chemistry 2008;80(16):6245-52.
2008: Yelena V Grinkova; Ilia Denisov; Michael R Waterman; Miharu Arase; Norio Kagawa; Stephen G Sligar
The ferrous-oxy complex of human aromatase.
Biochemical and biophysical research communications 2008;372(2):379-82.
2008: Karin Kühnel; Na Ke; Max J Cryle; Stephen G Sligar; Mary A Schuler; Ilme Schlichting
Crystal structures of substrate-free and retinoic acid-bound cyanobacterial cytochrome P450 CYP120A1.
Biochemistry 2008;47(25):6552-9.
2008: Martin E. Newcomb; James A Halgrimson; John H Horner; Erik C Wasinger; Lin X Chen; Stephen G Sligar
X-ray absorption spectroscopic characterization of a cytochrome P450 compound II derivative.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(24):8179-84.
2008: Amy Y Shih; Stephen G Sligar; Klaus Schulten
Molecular models need to be tested: the case of a solar flares discoidal HDL model.
Biophysical journal 2008;94(12):L87-9.
2008: Florin Gruia; Dan Ionascu; Minoru Kubo; Xiong Ye; John H Dawson; Robert L Osborne; Stephen G Sligar; Ilia Denisov; Aditi Das; T L Poulos; James Terner; Paul Champion
Low-frequency dynamics of Caldariomyces fumago chloroperoxidase probed by femtosecond coherence spectroscopy.
Biochemistry 2008;47(18):5156-67.
2008: Brian Hall; Mark A McLean; Kathryn Davis; James E Casanova; Stephen G Sligar; Martin A Schwartz
A fluorescence resonance energy transfer activation sensor for Arf6.
Analytical biochemistry 2008;374(2):243-9.
2008: James Morrissey; Vincent Pureza; Rebecca L Davis-Harrison; Stephen G Sligar; Y Zenmei Ohkubo; Emadeddin Emadeddin Tajkhorshid
Blood clotting reactions on nanoscale phospholipid bilayers.
Thrombosis research 2008;122 Suppl 1():S23-6.
2007: Thomas M Makris; Konstanze von Koenig; Ilme Schlichting; Stephen G Sligar
Alteration of P450 distal pocket solvent leads to impaired proton delivery and changes in heme geometry.
Biochemistry 2007;46(49):14129-40.
2007: Aleksandra Z Kijac; Ying Li; Stephen G Sligar; Chad M Rienstra
Magic-angle spinning solid-state NMR spectroscopy of nanodisc-embedded human CYP3A4.
Biochemistry 2007;46(48):13696-703.
2007: Ilia Denisov; John H Dawson; Lowell P Hager; Stephen G Sligar
The ferric-hydroperoxo complex of chloroperoxidase.
Biochemical and biophysical research communications 2007;363(4):954-8.
2007: Aditi Das; Yelena V Grinkova; Stephen G Sligar
Redox potential control by drug binding to cytochrome P450 3A4.
Journal of the American Chemical Society 2007;129(45):13778-9.
2007: Abhinav Nath; Yelena V Grinkova; Stephen G Sligar; William M Atkins
Ligand binding to cytochrome P450 3A4 in phospholipid bilayer nanodiscs: the effect of model membranes.
The Journal of biological chemistry 2007;282(39):28309-20.
2007: Amy Y Shih; Anton Arkhipov; Peter L Freddolino; Stephen G Sligar; Klaus Schulten
Assembly of lipids and proteins into lipoprotein particles.
The journal of physical chemistry. B 2007;111(38):11095-104.
2007: Ilia Denisov; Yelena V Grinkova; Mark A McLean; Stephen G Sligar
The one-electron autoxidation of human cytochrome P450 3A4.
The Journal of biological chemistry 2007;282(37):26865-73.
2007: Novelle Kimmich; Aditi Das; Irina F Sevrioukova; Yergalem T Meharenna; Stephen G Sligar; Thomas L Poulos
Electron transfer between cytochrome P450cin and its FMN-containing redox partner, cindoxin.
The Journal of biological chemistry 2007;282(37):27006-11.
2007: Dmitri Davydov; Bradley J Baas; Stephen G Sligar; James Halpert
Allosteric mechanisms in cytochrome P450 3A4 studied by high-pressure spectroscopy: pivotal role of substrate-induced changes in the accessibility and degree of hydration of the heme pocket.
Biochemistry 2007;46(26):7852-64.
2007: Amy Y Shih; Peter L Freddolino; Stephen G Sligar; Klaus Schulten
Disassembly of nanodiscs with cholate.
Nano letters 2007;7(6):1692-6.
2007: Q Zhao; G Sigalov; V Dimitrov; B Dorvel; Utkur Mirsaidov; Stephen G Sligar; Aleksij Aksimentiev; Gregory Timp
Detecting SNPs using a synthetic nanopore.
Nano letters 2007;7(6):1680-5.
2007: Piotr J Mak; Ilia Denisov; Doreen Victoria; Thomas M Makris; Tianjing Deng; Stephen G Sligar; James R Kincaid
Resonance Raman detection of the hydroperoxo intermediate in the cytochrome P450 enzymatic cycle.
Journal of the American Chemical Society 2007;129(20):6382-3.
2007: Timothy H Bayburt; Andrew J Leitz; Guifu Xie; Daniel D Oprian; Stephen G Sligar
Transducin activation by nanoscale lipid bilayers containing one and two rhodopsins.
The Journal of biological chemistry 2007;282(20):14875-81.
2007: Antoinette Chougnet; Yelena Grinkova; David Ricard; Stephen G Sligar; Wolf-D Woggon
Fluorescent probes for rapid screening of potential drug-drug interactions at the CYP3A4 level.
ChemMedChem 2007;2(5):717-24.
2007: Meriem Alami; Kush Dalal; Barbara Lelj-Garolla; Stephen G Sligar; Franck Duong
Nanodiscs unravel the interaction between the SecYEG channel and its cytosolic partner SecA.
The EMBO journal 2007;26(8):1995-2004.
2007: Ilia Denisov; Bradley J Baas; Yelena V Grinkova; Stephen G Sligar
Cooperativity in cytochrome P450 3A4: linkages in substrate binding, spin state, uncoupling, and product formation.
The Journal of biological chemistry 2007;282(10):7066-76.
2007: Andrew W Shaw; Vincent Pureza; Stephen G Sligar; James Morrissey
The local phospholipid environment modulates the activation of blood clotting.
The Journal of biological chemistry 2007;282(9):6556-63.
2007: Abhinav Nath; William M Atkins; Stephen G Sligar
Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins.
Biochemistry 2007;46(8):2059-69.
2007: Violeta L Marin; Timothy H Bayburt; Stephen G Sligar; Milan Mrksich
Functional assays of membrane-bound proteins with SAMDI-TOF mass spectrometry.
Angewandte Chemie (International ed. in English) 2007;46(46):8796-8.
2007: Stephen G Sligar; Ilia Denisov
Understanding cooperativity in human p450 mediated drug-drug interactions.
Drug metabolism reviews 2007;39(2-3):567-79.
2006: Ying Li; Aleksandra Z Kijac; Stephen G Sligar; Chad M Rienstra
Structural analysis of nanoscale self-assembled discoidal lipid bilayers by solid-state NMR spectroscopy.
Biophysical journal 2006;91(10):3819-28.
2006: Jing Zhao; Aditi Das; Xiaoyu Zhang; George C Schatz; Stephen G Sligar; Richard P Van Duyne
Resonance surface plasmon spectroscopy: low molecular weight substrate binding to cytochrome p450.
Journal of the American Chemical Society 2006;128(34):11004-5.
2006: Ilia Denisov; Yelena V Grinkova; Bradley J Baas; Stephen G Sligar
The ferrous-dioxygen intermediate in human cytochrome P450 3A4. Substrate dependence of formation and decay kinetics.
The Journal of biological chemistry 2006;281(33):23313-8.
2006: Thomas Boldog; Stephen Grimme; Mingshan Li; Stephen G Sligar; Gerald L Hazelbauer
Nanodiscs separate chemoreceptor oligomeric states and reveal their signaling properties.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(31):11509-14.
2006: Timothy H Bayburt; Yelena V Grinkova; Stephen G Sligar
Assembly of single bacteriorhodopsin trimers in bilayer nanodiscs.
Archives of biochemistry and biophysics 2006;450(2):215-22.
2006: Andrew J Leitz; Timothy H Bayburt; Alexander N Barnakov; Barry A Springer; Stephen G Sligar
Functional reconstitution of Beta2-adrenergic receptors utilizing self-assembling Nanodisc technology.
BioTechniques 2006;40(5):601-2, 604, 606, passim.
2006: Martin E. Newcomb; Rui Zhang; Ranepuradewage Chandrasena; James A Halgrimson; John H Horner; Thomas M Makris; Stephen G Sligar
Cytochrome p450 compound I.
Journal of the American Chemical Society 2006;128(14):4580-1.
2006: Thomas M Makris; Konstanze von Koenig; Ilme Schlichting; Stephen G Sligar
The status of high-valent metal oxo complexes in the P450 cytochromes.
Journal of inorganic biochemistry 2006;100(4):507-18.
2006: Jiunn B Heng; Aleksij Aksimentiev; Chien Ho; P Marks; Yelena V Grinkova; Stephen G Sligar; Klaus Schulten; Gregory Timp
The electromechanics of DNA in a synthetic nanopore.
Biophysical journal 2006;90(3):1098-106.
2005: Stephen G Sligar; Thomas M Makris; Ilia Denisov
Thirty years of microbial P450 monooxygenase research: peroxo-heme intermediates--the central bus station in heme oxygenase catalysis.
Biochemical and biophysical research communications 2005;338(1):346-54.
2005: Dmitri Davydov; Harshica Fernando; Bradley J Baas; Stephen G Sligar; James Halpert
Kinetics of dithionite-dependent reduction of cytochrome P450 3A4: heterogeneity of the enzyme caused by its oligomerization.
Biochemistry 2005;44(42):13902-13.
2005: Jiunn B Heng; Aleksij Aksimentiev; Chuen Ho; Patrick Marks; Yelena V Grinkova; Stephen G Sligar; Klaus Schulten; Gregory Timp
Stretching DNA using the electric field in a synthetic nanopore.
Nano letters 2005;5(10):1883-8.
2005: Ilia Denisov; Mark A McLean; Andrew W Shaw; Yelena V Grinkova; Stephen G Sligar
Thermotropic phase transition in soluble nanoscale lipid bilayers.
The journal of physical chemistry. B 2005;109(32):15580-8.
2005: Ilia Denisov; Thomas M Makris; Stephen G Sligar; Ilme Schlichting
Structure and chemistry of cytochrome P450.
Chemical reviews 2005;105(6):2253-77.
2005: Na Ke; Jerome Baudry; Thomas M Makris; Mary A Schuler; Stephen G Sligar
A retinoic acid binding cytochrome P450: CYP120A1 from Synechocystis sp. PCC 6803.
Archives of biochemistry and biophysics 2005;436(1):110-20.
2005: Masanori Sono; Roshan Perera; Shengxi Jin; Thomas M Makris; Stephen G Sligar; Thomas A Bryson; John H Dawson
The influence of substrate on the spectral properties of oxyferrous wild-type and T252A cytochrome P450-CAM.
Archives of biochemistry and biophysics 2005;436(1):40-9.
2005: Amy Y Shih; Ilia Denisov; James C Phillips; Stephen G Sligar; Klaus Schulten
Molecular dynamics simulations of discoidal bilayers assembled from truncated human lipoproteins.
Biophysical journal 2005;88(1):548-56.
2004: Bradley J Baas; Ilia Denisov; Stephen G Sligar
Homotropic cooperativity of monomeric cytochrome P450 3A4 in a nanoscale native bilayer environment.
Archives of biochemistry and biophysics 2004;430(2):218-28.
2004: Jiunn B Heng; Chuen Ho; Taekyung Kim; Rolf J Timp; Aleksij Aksimentiev; Yelena V Grinkova; Stephen G Sligar; Klaus Schulten; Gregory Timp
Sizing DNA using a nanometer-diameter pore.
Biophysical journal 2004;87(4):2905-11.
2004: Hui Duan; Natanya Civjan; Stephen G Sligar; Mary A Schuler
Co-incorporation of heterologously expressed Arabidopsis cytochrome P450 and P450 reductase into soluble nanoscale lipid bilayers.
Archives of biochemistry and biophysics 2004;424(2):141-53.
2004: Ilia Denisov; Yelena V Grinkova; A A Lazarides; Stephen G Sligar
Directed self-assembly of monodisperse phospholipid bilayer Nanodiscs with controlled size.
Journal of the American Chemical Society 2004;126(11):3477-87.
2004: Volker Schünemann; Friedhelm Lendzian; Christiane Jung; Jörg Contzen; Anne-Laure Barra; Stephen G Sligar; Alfred X Trautwein
Tyrosine radical formation in the reaction of wild type and mutant cytochrome P450cam with peroxy acids: a multifrequency EPR study of intermediates on the millisecond time scale.
The Journal of biological chemistry 2004;279(12):10919-30.
2004: Andrew W Shaw; Mark A McLean; Stephen G Sligar
Phospholipid phase transitions in homogeneous nanometer scale bilayer discs.
FEBS letters 2004;556(1-3):260-4.
2003: Stephen G Sligar
Finding a single-molecule solution for membrane proteins.
Biochemical and biophysical research communications 2003;312(1):115-9.
2003: Minor J Coon; Stephen G Sligar
Irwin C. Gunsalus, versatile and creative scientist.
Biochemical and biophysical research communications 2003;312(1):1-6, 9-27.
2003: Mohammed Ibrahim; Ilia Denisov; Thomas M Makris; James R Kincaid; Stephen G Sligar
Resonance Raman spectroscopic studies of hydroperoxo-myoglobin at cryogenic temperatures.
Journal of the American Chemical Society 2003;125(45):13714-8.
2003: Timothy H Bayburt; Stephen G Sligar
Self-assembly of single integral membrane proteins into soluble nanoscale phospholipid bilayers.
Protein science : a publication of the Protein Society 2003;12(11):2476-81.
2003: Natanya Civjan; Timothy H Bayburt; Mary A Schuler; Stephen G Sligar
Direct solubilization of heterologously expressed membrane proteins by incorporation into nanoscale lipid bilayers.
BioTechniques 2003;35(3):556-60, 562-3.
2003: Gjalt Huisman; Stephen G Sligar
Evolution of protein technologies from voodoo to science.
Current opinion in biotechnology 2003;14(4):357-9.
2003: Thomas M Makris; Ilia Denisov; Stephen G Sligar
Haem-oxygen reactive intermediates: catalysis by the two-step.
Biochemical Society transactions 2003;31(Pt 3):516-9.
2003: Shengxi Jin; Thomas M Makris; Thomas A Bryson; Stephen G Sligar; John H Dawson
Epoxidation of olefins by hydroperoxo-ferric cytochrome P450.
Journal of the American Chemical Society 2003;125(12):3406-7.
2002: Ilia Denisov; Masao Ikeda-Saito; Tadashi Yoshida; Stephen G Sligar
Cryogenic absorption spectra of hydroperoxo-ferric heme oxygenase, the active intermediate of enzymatic heme oxygenation.
FEBS letters 2002;532(1-2):203-6.
2002: Ilia Denisov; Thomas M Makris; Stephen G Sligar
Formation and decay of hydroperoxo-ferric heme complex in horseradish peroxidase studied by cryoradiolysis.
The Journal of biological chemistry 2002;277(45):42706-10.
2002: Thomas M Makris; Roman Davydov; Ilia Denisov; Brian M Hoffman; Stephen G Sligar
Mechanistic enzymology of oxygen activation by the cytochromes P450.
Drug metabolism reviews 2002;34(4):691-708.
2002: Sam-Yong Park; Kazuhide Yamane; Shin-ichi Adachi; Yoshitsugu Shiro; Kara E Weiss; Shelley A Maves; Stephen G Sligar
Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties.
Journal of inorganic biochemistry 2002;91(4):491-501.
2002: Kevin E Sanders; John Lo; Stephen G Sligar
Intersubunit circular permutation of human hemoglobin.
Blood 2002;100(1):299-305.
2002: Timothy H Bayburt; Stephen G Sligar
Single-molecule height measurements on microsomal cytochrome P450 in nanometer-scale phospholipid bilayer disks.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):6725-30.
2002: Gaston Hui Bon Hoa; Mark A McLean; Stephen G Sligar
High pressure, a tool for exploring heme protein active sites.
Biochimica et biophysica acta 2002;1595(1-2):297-308.
2002: Thomas W Lynch; Stephen G Sligar
Experimental and theoretical high pressure strategies for investigating protein-nucleic acid assemblies.
Biochimica et biophysica acta 2002;1595(1-2):277-82.
2002: David G Kellner; Shao-Ching Hung; Kara E Weiss; Stephen G Sligar
Kinetic characterization of compound I formation in the thermostable cytochrome P450 CYP119.
The Journal of biological chemistry 2002;277(12):9641-4.
2002: Masashi Unno; James F Christian; Theodore SJodin; David E Benson; Iain D G Macdonald; Stephen G Sligar; Paul Champion
Complex formation of cytochrome P450cam with Putidaredoxin. Evidence for protein-specific interactions involving the proximal thiolate ligand.
The Journal of biological chemistry 2002;277(4):2547-53.
2002: Ivan J Dmochowski; Alexander R Dunn; Jonathan J Wilker; Brian R Crane; Michael T Green; John H Dawson; Stephen G Sligar; Jay R Winkler; Harry B Gray
Sensitizer-linked substrates and ligands: ruthenium probes of cytochrome P450 structure and mechanism.
Methods in enzymology 2002;357():120-33.
2002: Ilia Denisov; Thomas M Makris; Stephen G Sligar
Cryoradiolysis for the study of P450 reaction intermediates.
Methods in enzymology 2002;357():103-15.
2002: Thomas W Lynch; Dorina Kosztin; Mark A McLean; Klaus Schulten; Stephen G Sligar
Dissecting the molecular origins of specific protein-nucleic acid recognition: hydrostatic pressure and molecular dynamics.
Biophysical journal 2002;82(1 Pt 1):93-8.
2001: Ilia Denisov; S C Hung; Kara E Weiss; Mark A McLean; Yoshitsugu Shiro; Sam-Yong Park; Paul Champion; Stephen G Sligar
Characterization of the oxygenated intermediate of the thermophilic cytochrome P450 CYP119.
Journal of inorganic biochemistry 2001;87(4):215-26.
2001: Yuri D Ivanov; IP Kanaeva; II Karuzina; S A Usanov; Gaston Hui Bon Hoa; Stephen G Sligar; Alexander I Archakov
Revelation of ternary complexes between redox partners in cytochrome P450-containing monooxygenase systems by the optical biosensor method.
Journal of inorganic biochemistry 2001;87(4):175-84.
2001: Yuri D Ivanov; IP Kanaeva; II Karuzina; Alexander I Archakov; Gaston Hui Bon Hoa; Stephen G Sligar
Molecular recognition in the p450cam monooxygenase system: direct monitoring of protein-protein interactions by using optical biosensor.
Archives of biochemistry and biophysics 2001;391(2):255-64.
2001: Theodore SJodin; James F Christian; Iain D G Macdonald; R Davydov; Masashi Unno; Stephen G Sligar; B M Hoffman; Paul Champion
Resonance Raman and EPR investigations of the D251N oxycytochrome P450cam/putidaredoxin complex.
Biochemistry 2001;40(23):6852-9.
2001: Ilia Denisov; Thomas M Makris; Stephen G Sligar
Cryotrapped reaction intermediates of cytochrome p450 studied by radiolytic reduction with phosphorus-32.
The Journal of biological chemistry 2001;276(15):11648-52.
2001: Roman Davydov; Thomas M Makris; Viktoria Kofman; D E Werst; Stephen G Sligar; Brian M Hoffman
Hydroxylation of camphor by reduced oxy-cytochrome P450cam: mechanistic implications of EPR and ENDOR studies of catalytic intermediates in native and mutant enzymes.
Journal of the American Chemical Society 2001;123(7):1403-15.
2001: Tianjing Deng; Iain D G Macdonald; M C Simianu; M Sykora; James R Kincaid; Stephen G Sligar
Hydrogen-bonding interactions in the active sites of cytochrome P450cam and its site-directed mutants.
Journal of the American Chemical Society 2001;123(2):269-78.
2001: Shelley A Maves; Stephen G Sligar
Understanding thermostability in cytochrome P450 by combinatorial mutagenesis.
Protein science : a publication of the Protein Society 2001;10(1):161-8.
2000: Thomas W Lynch; Stephen G Sligar
Macromolecular hydration changes associated with BamHI binding and catalysis.
The Journal of biological chemistry 2000;275(39):30561-5.
2000: M L Shank-Retzlaff; Stephen G Sligar
Analyte gradient-surface plasmon resonance: a one-step method for determining kinetic rates and macromolecular binding affinities.
Analytical chemistry 2000;72(17):4212-20.
2000: Sam-Yong Park; K Yamane; S Adachi; Yoshitsugu Shiro; Kara E Weiss; Stephen G Sligar
Crystallization and preliminary X-ray diffraction analysis of a cytochrome P450 (CYP119) from Sulfolobus solfataricus.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 9):1173-5.
2000: S E Bondos; Stephen G Sligar; J Jonas
High-pressure denaturation of apomyoglobin.
Biochimica et biophysica acta 2000;1480(1-2):353-64.
2000: Ilme Schlichting; Joel Berendzen; K Chu; A M Stock; Shelley A Maves; David E Benson; RM Sweet; D Ringe; G A Petsko; Stephen G Sligar
The catalytic pathway of cytochrome p450cam at atomic resolution.
Science (New York, N.Y.) 2000;287(5458):1615-22.
1999: Tianjing Deng; Leonard M Proniewicz; James R Kincaid; H Yeom; Iain D G Macdonald; Stephen G Sligar
Resonance Raman studies of cytochrome P450BM3 and its complexes with exogenous ligands.
Biochemistry 1999;38(41):13699-706.
1999: Joachim D Müller; B H McMahon; E Y Chien; Stephen G Sligar; G Ulrich Nienhaus
Connection between the taxonomic substates and protonation of histidines 64 and 97 in carbonmonoxy myoglobin.
Biophysical journal 1999;77(2):1036-51.
1999: Stephen G Sligar
Nature's universal oxygenases: the cytochromes P450.
Essays in biochemistry 1999;34():71-83.
1998: Mark A McLean; Shelley A Maves; Kara E Weiss; S Krepich; Stephen G Sligar
Characterization of a cytochrome P450 from the acidothermophilic archaea Sulfolobus solfataricus.
Biochemical and biophysical research communications 1998;252(1):166-72.
1998: M L Shank-Retzlaff; Gregory M Raner; Minor J Coon; Stephen G Sligar
Membrane topology of cytochrome P450 2B4 in Langmuir-Blodgett monolayers.
Archives of biochemistry and biophysics 1998;359(1):82-8.
1998: Timothy H Bayburt; Joseph Carlson; Stephen G Sligar
Reconstitution and imaging of a membrane protein in a nanometer-size phospholipid bilayer.
Journal of structural biology 1998;123(1):37-44.
1998: Eric S Peterson; Joel Mitchel Friedman; E Y Chien; Stephen G Sligar
Functional implications of the proximal hydrogen-bonding network in myoglobin: a resonance Raman and kinetic study of Leu89, Ser92, His97, and F-helix swap mutants.
Biochemistry 1998;37(35):12301-19.
1998: M Vidakovic; Stephen G Sligar; H Li; T L Poulos
Understanding the role of the essential Asp251 in cytochrome p450cam using site-directed mutagenesis, crystallography, and kinetic solvent isotope effect.
Biochemistry 1998;37(26):9211-9.
1998: Y Wu; E Y Chien; Stephen G Sligar; Gerd N La Mar
Influence of proximal side mutations on the molecular and electronic structure of cyanomet myoglobin: an 1H NMR study.
Biochemistry 1998;37(19):6979-90.
1998: CR Robinson; Y Liu; R O'Brien; Stephen G Sligar; Julian M Sturtevant
A differential scanning calorimetric study of the thermal unfolding of apo- and holo-cytochrome b562.
Protein science : a publication of the Protein Society 1998;7(4):961-5.
1998: Laura D Kwiatkowski; Hilda L Hui; Anita Wierzba; Robert W Noble; R Y Walder; Eric S Peterson; Stephen G Sligar; K E Sanders
Preparation and kinetic characterization of a series of betaW37 variants of human hemoglobin A: evidence for high-affinity T quaternary structures.
Biochemistry 1998;37(13):4325-35.
1998: CR Robinson; Stephen G Sligar
Changes in solvation during DNA binding and cleavage are critical to altered specificity of the EcoRI endonuclease.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2186-91.
1998: Mark A McLean; Carmelo Di Primo; Eric Deprez; Gaston Hui Bon Hoa; Stephen G Sligar
Photoacoustic calorimetry of proteins.
Methods in enzymology 1998;295():316-30.
1997: CR Robinson; Y Liu; J A Thomson; Julian M Sturtevant; Stephen G Sligar
Energetics of heme binding to native and denatured states of cytochrome b562.
Biochemistry 1997;36(51):16141-6.
1997: James F Christian; Masashi Unno; J Timothy Sage; Paul Champion; E Chien; Stephen G Sligar
Spectroscopic effects of polarity and hydration in the distal heme pocket of deoxymyoglobin.
Biochemistry 1997;36(37):11198-204.
1997: Shelley A Maves; H Yeom; Mark A McLean; Stephen G Sligar
Decreased substrate affinity upon alteration of the substrate-docking region in cytochrome P450(BM-3).
FEBS letters 1997;414(2):213-8.
1997: Joseph Carlson; Ana Jonas; Stephen G Sligar
Imaging and manipulation of high-density lipoproteins.
Biophysical journal 1997;73(3):1184-9.
1997: D G Kellner; Shelley A Maves; Stephen G Sligar
Engineering cytochrome P450s for bioremediation.
Current opinion in biotechnology 1997;8(3):274-8.
1997: David E Benson; Kenneth S Suslick; Stephen G Sligar
Reduced oxy intermediate observed in D251N cytochrome P450cam.
Biochemistry 1997;36(17):5104-7.
1997: J G Pearson; B Montez; H Le; Eric Oldfield; E Y Chien; Stephen G Sligar
Assignment and analysis of fluorine nuclear magnetic resonance spectra of 4-fluorotryptophan myoglobins and hemoglobins.
Biochemistry 1997;36(12):3590-9.
1997: H Yeom; Stephen G Sligar
Oxygen activation by cytochrome P450BM-3: effects of mutating an active site acidic residue.
Archives of biochemistry and biophysics 1997;337(2):209-16.
1997: Carmelo Di Primo; Eric Deprez; Stephen G Sligar; Gaston Hui Bon Hoa
Origin of the photoacoustic signal in cytochrome P-450cam: role of the Arg186-Asp251-Lys178 bifurcated salt bridge.
Biochemistry 1997;36(1):112-8.
1996: S R Blanke; Susan A Martinis; Stephen G Sligar; Lowell P Hager; J J Rux; John H Dawson
Probing the heme iron coordination structure of alkaline chloroperoxidase.
Biochemistry 1996;35(46):14537-43.
1996: Susan A Martinis; S R Blanke; Lowell P Hager; Stephen G Sligar; G H Hoa; J J Rux; John H Dawson
Probing the heme iron coordination structure of pressure-induced cytochrome P420cam.
Biochemistry 1996;35(46):14530-6.
1996: C R Robinson; Stephen G Sligar
Participation of water in Hin recombinase--DNA recognition.
Protein science : a publication of the Protein Society 1996;5(10):2119-24.
1996: K E Sanders; G Ackers; Stephen G Sligar
Engineering and design of blood substitutes.
Current opinion in structural biology 1996;6(4):534-40.
1996: W D Tian; J Timothy Sage; Paul Champion; E Chien; Stephen G Sligar
Probing heme protein conformational equilibration rates with kinetic selection.
Biochemistry 1996;35(11):3487-502.
1996: Christiane Jung; Otto Ristau; H Schulze; Stephen G Sligar
The CO stretching mode infrared spectrum of substrate-free cytochrome P-450cam-CO: the effect of solvent conditions, temperature, and pressure.
European journal of biochemistry / FEBS 1996;235(3):660-9.
1996: Mark A McLean; H Yeom; Stephen G Sligar
Carbon monoxide binding to cytochrome P450BM-3: evidence for a substrate-dependent conformational change.
Biochimie 1996;78(8-9):700-5.
1995: H Yeom; Stephen G Sligar; H Li; T L Poulos; A J Fulco
The role of Thr268 in oxygen activation of cytochrome P450BM-3.
Biochemistry 1995;34(45):14733-40.
1995: R A Hernan; Stephen G Sligar
Tetrameric hemoglobin expressed in Escherichia coli. Evidence of heterogeneous subunit assembly.
The Journal of biological chemistry 1995;270(44):26257-64.
1995: A Dumoulin; Laurent Kiger; R Jiang; V Baudin; C Vasseur; Stephen G Sligar; Michael C Marden; Josée Pagnier; Claude Poyart
Loss of allosteric behaviour in recombinant hemoglobin alpha 2 beta 2(92)(F8) His-->Ala: restoration upon addition of strong effectors.
FEBS letters 1995;374(1):39-42.
1995: M A McLean; Stephen G Sligar
Thermodynamic characterization of the interaction between cytochrome b5 and cytochrome c.
Biochemical and biophysical research communications 1995;215(1):316-20.
1995: Bill Durham; J L Fairris; M McLean; Francis Millett; Jill Scott; Stephen G Sligar; A Willie
Electron transfer from cytochrome b5 to cytochrome c.
Journal of bioenergetics and biomembranes 1995;27(3):331-40.
1995: Y Abadan; E Y Chien; K Chu; C D Eng; G Ulrich Nienhaus; Stephen G Sligar
Ligand binding to heme proteins. V. Light-induced relaxation in proximal mutants L89I and H97F of carbonmonoxymyoglobin.
Biophysical journal 1995;68(6):2497-504.
1995: W D Tian; A V Wells; Paul Champion; Carmelo Di Primo; N Gerber; Stephen G Sligar
Measurements of CO geminate recombination in cytochromes P450 and P420.
The Journal of biological chemistry 1995;270(15):8673-9.
1995: C R Robinson; Stephen G Sligar
Heterogeneity in molecular recognition by restriction endonucleases: osmotic and hydrostatic pressure effects on BamHI, Pvu II, and EcoRV specificity.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3444-8.
1995: P J Loida; Stephen G Sligar; M D Paulsen; G E Arnold; RL Ornstein
Stereoselective hydroxylation of norcamphor by cytochrome P450cam. Experimental verification of molecular dynamics simulations.
The Journal of biological chemistry 1995;270(10):5326-30.
1995: Clifford R Robinson; Stephen G Sligar
Hydrostatic and osmotic pressure as tools to study macromolecular recognition.
Methods in enzymology 1995;259():395-427.
1994: Eric Deprez; N C Gerber; Carmelo Di Primo; P Douzou; Stephen G Sligar; Gaston Hui Bon Hoa
Electrostatic control of the substrate access channel in cytochrome P-450cam.
Biochemistry 1994;33(48):14464-8.
1994: Gerd N La Mar; F Dalichow; X Zhao; Y Dou; Masao Ikeda-Saito; M L Chiu; Stephen G Sligar
1H NMR investigation of distal mutant deoxy myoglobins. Interpretation of proximal His contact shifts in terms of a localized distal water molecule.
The Journal of biological chemistry 1994;269(47):29629-35.
1994: Serge Pin; Bernard Alpert; R Cortès; Isabella Ascone; M L Chiu; Stephen G Sligar
The heme iron coordination complex in His64(E7)Tyr recombinant sperm whale myoglobin.
Biochemistry 1994;33(38):11618-23.
1994: Y Thériault; T C Pochapsky; C Dalvit; M L Chiu; Stephen G Sligar; Peter Wright
1H and 15N resonance assignments and secondary structure of the carbon monoxide complex of sperm whale myoglobin.
Journal of biomolecular NMR 1994;4(4):491-504.
1994: K Rajarathnam; J Qin; Gerd N La Mar; M L Chiu; Stephen G Sligar
Correlation between the steric bulk of the distal E7 and E11 residues and the tilt of the FeCN unit in cyanometmyoglobin as determined by NMR from the orientation of the magnetic axes in single and double point mutants.
Biochemistry 1994;33(18):5493-501.
1994: C R Robinson; Stephen G Sligar
Hydrostatic pressure reverses osmotic pressure effects on the specificity of EcoRI-DNA interactions.
Biochemistry 1994;33(13):3787-93.
1994: N C Gerber; Stephen G Sligar
A role for Asp-251 in cytochrome P-450cam oxygen activation.
The Journal of biological chemistry 1994;269(6):4260-6.
1994: J E Erman; Lowell P Hager; Stephen G Sligar
Cytochrome P-450 and peroxidase chemistry.
Advances in inorganic biochemistry 1994;10():71-118.
1994: Y Feng; Stephen G Sligar; A J Wand
Solution structure of apocytochrome b562.
Nature structural biology 1994;1(1):30-5.
1993: D P Braunstein; K Chu; K D Egeberg; H Frauenfelder; J R Mourant; G Ulrich Nienhaus; Pál Ormos; Stephen G Sligar; B A Springer; R D Young
Ligand binding to heme proteins: III. FTIR studies of His-E7 and Val-E11 mutants of carbonmonoxymyoglobin.
Biophysical journal 1993;65(6):2447-54.
1993: B Nölting; Stephen G Sligar
Adiabatic compressibility of molten globules.
Biochemistry 1993;32(46):12319-23.
1993: C R Robinson; Stephen G Sligar
Molecular recognition mediated by bound water. A mechanism for star activity of the restriction endonuclease EcoRI.
Journal of molecular biology 1993;234(2):302-6.
1993: P J Loida; Stephen G Sligar
Molecular recognition in cytochrome P-450: mechanism for the control of uncoupling reactions.
Biochemistry 1993;32(43):11530-8.
1993: K B Lee; Gerd N La Mar; K E Mansfield; K M Smith; T C Pochapsky; Stephen G Sligar
Interpretation of hyperfine shift patterns in ferricytochromes b5 in terms of angular position of the heme: a sensitive probe for peripheral heme protein interactions.
Biochimica et biophysica acta 1993;1202(2):189-99.
1993: T Koch; J D Ropp; Stephen G Sligar; G B Schuster
Photocleavage of DNA: irradiation of quinone-containing reagents converts supercoiled to linear DNA.
Photochemistry and photobiology 1993;58(4):554-8.
1993: M A McLean; P S Stayton; Stephen G Sligar
Engineering protein orientation at surfaces to control macromolecular recognition events.
Analytical chemistry 1993;65(19):2676-8.
1993: J D Ropp; I C Gunsalus; Stephen G Sligar
Cloning and expression of a member of a new cytochrome P-450 family: cytochrome P-450lin (CYP111) from Pseudomonas incognita.
Journal of bacteriology 1993;175(18):6028-37.
1993: A Willie; M McLean; R Q Liu; S Hilgen-Willis; Aleister J Saunders; Gary J Pielak; Stephen G Sligar; Bill Durham; Francis Millett
Intracomplex electron transfer between ruthenium-65-cytochrome b5 and position-82 variants of yeast iso-1-cytochrome c.
Biochemistry 1993;32(29):7519-25.
1993: K Rajarathnam; J Qin; Gerd N La Mar; M L Chiu; Stephen G Sligar
Solution structure determination of the heme cavity in the E7 His-->Val cyano-met myoglobin point mutant based on the 1H NMR detected dipolar field of the iron: evidence for contraction of the heme pocket.
Biochemistry 1993;32(21):5670-80.
1993: C R Robinson; Stephen G Sligar
Electrostatic stabilization in four-helix bundle proteins.
Protein science : a publication of the Protein Society 1993;2(5):826-37.
1993: Carmelo Di Primo; Gaston Hui Bon Hoa; Eric Deprez; P Douzou; Stephen G Sligar
Conformational dynamics of cytochrome P-450cam as monitored by photoacoustic calorimetry.
Biochemistry 1993;32(14):3671-6.
1993: M D Paulsen; D Filipovic; Stephen G Sligar; RL Ornstein
Controlling the regiospecificity and coupling of cytochrome P450cam: T185F mutant increases coupling and abolishes 3-hydroxynorcamphor product.
Protein science : a publication of the Protein Society 1993;2(3):357-65.
1993: P J Loida; Stephen G Sligar
Engineering cytochrome P-450cam to increase the stereospecificity and coupling of aliphatic hydroxylation.
Protein engineering 1993;6(2):207-12.
1992: D Filipovic; M D Paulsen; P J Loida; Stephen G Sligar; RL Ornstein
Ethylbenzene hydroxylation by cytochrome P450cam.
Biochemical and biophysical research communications 1992;189(1):488-95.
1992: M D Davies; Stephen G Sligar
Genetic variants in the putidaredoxin-cytochrome P-450cam electron-transfer complex: identification of the residue responsible for redox-state-dependent conformers.
Biochemistry 1992;31(46):11383-9.
1992: Carmelo Di Primo; Stephen G Sligar; G H Hoa; P Douzou
A critical role of protein-bound water in the catalytic cycle of cytochrome P-450 camphor.
FEBS letters 1992;312(2-3):252-4.
1992: Carmelo Di Primo; Gaston Hui Bon Hoa; P Douzou; Stephen G Sligar
Heme-pocket-hydration change during the inactivation of cytochrome P-450camphor by hydrostatic pressure.
European journal of biochemistry / FEBS 1992;209(2):583-8.
1992: R A Hernan; Hilda L Hui; M E Andracki; Robert W Noble; Stephen G Sligar; J A Walder; Roxanne Y Walder
Human hemoglobin expression in Escherichia coli: importance of optimal codon usage.
Biochemistry 1992;31(36):8619-28.
1992: B R Van Dyke; D A Bakan; K A Glover; J C Hegenauer; P Saltman; B A Springer; Stephen G Sligar
Site-directed mutagenesis of histidine residues involved in Cu(II) binding and reduction by sperm whale myoglobin.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(17):8016-9.
1992: A Willie; P S Stayton; Stephen G Sligar; Bill Durham; Francis Millett
Genetic engineering of redox donor sites: measurement of intracomplex electron transfer between ruthenium-65-cytochrome b5 and cytochrome c.
Biochemistry 1992;31(32):7237-42.
1992: W Fu; P M Drozdzewski; M D Davies; Stephen G Sligar; Michael K Johnson
Resonance Raman and magnetic circular dichroism studies of reduced [2Fe-2S] proteins.
The Journal of biological chemistry 1992;267(22):15502-10.
1992: Stephen G Sligar; Francis Salemme
Protein engineering for molecular electronics.
Current opinion in biotechnology 1992;3(4):388-93.
1992: A V Wells; P Li; Paul Champion; Susan A Martinis; Stephen G Sligar
Resonance Raman investigations of Escherichia coli-expressed Pseudomonas putida cytochrome P450 and P420.
Biochemistry 1992;31(18):4384-93.
1991: H Frauenfelder; Stephen G Sligar; P G Wolynes
The energy landscapes and motions of proteins.
Science (New York, N.Y.) 1991;254(5038):1598-603.
1991: H Nikkila; Robert B Gennis; Stephen G Sligar
Cloning and expression of the gene encoding the soluble cytochrome b562 of Escherichia coli.
European journal of biochemistry / FEBS 1991;202(2):309-13.
1991: R Raag; Susan A Martinis; Stephen G Sligar; Thomas L Poulos
Crystal structure of the cytochrome P-450CAM active site mutant Thr252Ala.
Biochemistry 1991;30(48):11420-9.
1991: Y Q Feng; Stephen G Sligar
Effect of heme binding on the structure and stability of Escherichia coli apocytochrome b562.
Biochemistry 1991;30(42):10150-5.
1991: Karla K. Rodgers; Stephen G Sligar
Mapping electrostatic interactions in macromolecular associations.
Journal of molecular biology 1991;221(4):1453-60.
1991: Y Q Feng; A Joshua Wand; Stephen G Sligar
1H and 15N NMR resonance assignments and preliminary structural characterization of Escherichia coli apocytochrome b562.
Biochemistry 1991;30(31):7711-7.
1991: Theodore E Carver; John S Olson; Stephen John Smerdon; S Krzywda; Anthony J Wilkinson; Quentin H Gibson; R S Blackmore; J D Ropp; Stephen G Sligar
Contributions of residue 45(CD3) and heme-6-propionate to the biomolecular and geminate recombination reactions of myoglobin.
Biochemistry 1991;30(19):4697-705.
1991: Francesca Cutruzzolà; C T Allocatelli; Paolo Ascenzi; M Bolognesi; Stephen G Sligar; Maurizio Brunori
Control and recognition of anionic ligands in myoglobin.
FEBS letters 1991;282(2):281-4.
1991: K D Park; K M Guo; F Adebodun; M L Chiu; Stephen G Sligar; Eric Oldfield
Distal and proximal ligand interactions in heme proteins: correlations between C-O and Fe-C vibrational frequencies, oxygen-17 and carbon-13 nuclear magnetic resonance chemical shifts, and oxygen-17 nuclear quadrupole coupling constants in C17O- and 13CO-labeled species.
Biochemistry 1991;30(9):2333-47.
1991: J Z Wu; Gerd N La Mar; L P Yu; K B Lee; F A Walker; M L Chiu; Stephen G Sligar
1H NMR study of the solution molecular and electronic structure of Escherichia coli ferricytochrome b562: evidence for S = 1/2 in equilibrium S = 5/2 spin equilibrium for intact His/Met ligation.
Biochemistry 1991;30(8):2156-65.
1991: P S Stayton; Stephen G Sligar
Structural microheterogeneity of a tryptophan residue required for efficient biological electron transfer between putidaredoxin and cytochrome P-450cam.
Biochemistry 1991;30(7):1845-51.
1991: Stephen G Sligar; D Filipovic; P S Stayton
Mutagenesis of cytochromes P450cam and b5.
Methods in enzymology 1991;206():31-49.
1990: Theodore E Carver; R J Rohlfs; John S Olson; Quentin H Gibson; R S Blackmore; B A Springer; Stephen G Sligar
Analysis of the kinetic barriers for ligand binding to sperm whale myoglobin using site-directed mutagenesis and laser photolysis techniques.
The Journal of biological chemistry 1990;265(32):20007-20.
1990: Andrea Bellelli; Giovanni Antonini; Maurizio Brunori; B A Springer; Stephen G Sligar
Transient spectroscopy of the reaction of cyanide with ferrous myoglobin. Effect of distal side residues.
The Journal of biological chemistry 1990;265(31):18898-901.
1990: Carmelo Di Primo; Gaston Hui Bon Hoa; P Douzou; Stephen G Sligar
Effect of the tyrosine 96 hydrogen bond on the inactivation of cytochrome P-450cam induced by hydrostatic pressure.
European journal of biochemistry / FEBS 1990;193(2):383-6.
1990: K D Egeberg; B A Springer; Susan A Martinis; Stephen G Sligar; D Morikis; Paul Champion
Alteration of sperm whale myoglobin heme axial ligation by site-directed mutagenesis.
Biochemistry 1990;29(42):9783-91.
1990: K B Lee; Gerd N La Mar; L A Kehres; E M Fujinari; K M Smith; T C Pochapsky; Stephen G Sligar
1H NMR study of the influence of hydrophobic contacts on protein-prosthetic group recognition in bovine and rat ferricytochrome b5.
Biochemistry 1990;29(41):9623-31.
1990: P S Stayton; Stephen G Sligar
The cytochrome P-450cam binding surface as defined by site-directed mutagenesis and electrostatic modeling.
Biochemistry 1990;29(32):7381-6.
1990: Mustak A Kaderbhai; Stephen G Sligar; T Barnfield; T Reames; J Gallagher; M He; E I Mercer; Naheed N Kaderbhai
A novel series of pEX-PINK expression vectors for screening high-level production of (un)fused foreign proteins by rapid visual detection of PINK Escherichia coli clones.
Nucleic acids research 1990;18(15):4629-30.
1990: D Morikis; Paul Champion; B A Springer; K D Egebey; Stephen G Sligar
Resonance Raman studies of iron spin and axial coordination in distal pocket mutants of ferric myoglobin.
The Journal of biological chemistry 1990;265(21):12143-5.
1990: Gaston Hui Bon Hoa; Carmelo Di Primo; M Geze; P Douzou; Jack A Kornblatt; Stephen G Sligar
The formation of cytochrome P-450 from cytochrome P-420 is promoted by spermine.
Biochemistry 1990;29(29):6810-5.
1990: J A Westrick; K S Peters; J D Ropp; Stephen G Sligar
Role of the arginine-45 salt bridge in ligand dissociation from sperm whale carboxymyoglobin as probed by photoacoustic calorimetry.
Biochemistry 1990;29(28):6741-6.
1990: K D Egeberg; B A Springer; Stephen G Sligar; Theodore E Carver; R J Rohlfs; John S Olson
The role of Val68(E11) in ligand binding to sperm whale myoglobin. Site-directed mutagenesis of a synthetic gene.
The Journal of biological chemistry 1990;265(20):11788-95.
1990: N C Gerber; T Horiuchi; H Koga; Stephen G Sligar
Identification of 2Fe-2S cysteine ligands in putidaredoxin.
Biochemical and biophysical research communications 1990;169(3):1016-20.
1990: Carmelo Di Primo; Gaston Hui Bon Hoa; P Douzou; Stephen G Sligar
Mutagenesis of a single hydrogen bond in cytochrome P-450 alters cation binding and heme solvation.
The Journal of biological chemistry 1990;265(10):5361-3.
1990: R J Rohlfs; A J Mathews; Theodore E Carver; John S Olson; B A Springer; K D Egeberg; Stephen G Sligar
The effects of amino acid substitution at position E7 (residue 64) on the kinetics of ligand binding to sperm whale myoglobin.
The Journal of biological chemistry 1990;265(6):3168-76.
1990: W M Atkins; Stephen G Sligar
Tyrosine-96 as a natural spectroscopic probe of the cytochrome P-450cam active site.
Biochemistry 1990;29(5):1271-5.
1990: George N Phillips; R M Arduini; B A Springer; Stephen G Sligar
Crystal structure of myoglobin from a synthetic gene.
Proteins 1990;7(4):358-65.
1989: P S Stayton; T L Poulos; Stephen G Sligar
Putidaredoxin competitively inhibits cytochrome b5-cytochrome P-450cam association: a proposed molecular model for a cytochrome P-450cam electron-transfer complex.
Biochemistry 1989;28(20):8201-5.
1989: D Morikis; Paul Champion; B A Springer; Stephen G Sligar
Resonance raman investigations of site-directed mutants of myoglobin: effects of distal histidine replacement.
Biochemistry 1989;28(11):4791-800.
1989: B A Springer; K D Egeberg; Stephen G Sligar; R J Rohlfs; A J Mathews; John S Olson
Discrimination between oxygen and carbon monoxide and inhibition of autooxidation by myoglobin. Site-directed mutagenesis of the distal histidine.
The Journal of biological chemistry 1989;264(6):3057-60.
1989: Gaston Hui Bon Hoa; Carmelo Di Primo; I Dondaine; Stephen G Sligar; I C Gunsalus; P Douzou
Conformational changes of cytochromes P-450cam and P-450lin induced by high pressure.
Biochemistry 1989;28(2):651-6.
1989: Susan A Martinis; C Sotiriou; C K Chang; Stephen G Sligar
Characterization of cytochrome b5 reconstituted with a ferric chlorin and a ferric oxochlorin.
Biochemistry 1989;28(2):879-84.
1988: W M Atkins; Stephen G Sligar
The roles of active site hydrogen bonding in cytochrome P-450cam as revealed by site-directed mutagenesis.
The Journal of biological chemistry 1988;263(35):18842-9.
1988: John S Olson; A J Mathews; R J Rohlfs; B A Springer; K D Egeberg; Stephen G Sligar; Jeremy R H Tame; J P Renaud; K Nagai
The role of the distal histidine in myoglobin and haemoglobin.
Nature 1988;336(6196):265-6.
1988: G Padbury; Stephen G Sligar; R Labeque; Lawrence J Marnett
Ferric bleomycin catalyzed reduction of 10-hydroperoxy-8,12-octadecadienoic acid: evidence for homolytic O-O bond scission.
Biochemistry 1988;27(20):7846-52.
1988: P S Stayton; M T Fisher; Stephen G Sligar
Determination of cytochrome b5 association reactions. Characterization of metmyoglobin and cytochrome P-450cam binding to genetically engineered cytochromeb5.
The Journal of biological chemistry 1988;263(27):13544-8.
1988: Karla K. Rodgers; T C Pochapsky; Stephen G Sligar
Probing the mechanisms of macromolecular recognition: the cytochrome b5-cytochrome c complex.
Science (New York, N.Y.) 1988;240(4859):1657-9.
1988: W M Atkins; Stephen G Sligar
Deuterium isotope effects in norcamphor metabolism by cytochrome P-450cam: kinetic evidence for the two-electron reduction of a high-valent iron-oxo intermediate.
Biochemistry 1988;27(5):1610-6.
1987: B A Springer; Stephen G Sligar
High-level expression of sperm whale myoglobin in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(24):8961-5.
1987: D R Jollie; Stephen G Sligar; M Schuler
Purification and Characterization of Microsomal Cytochrome b(5) and NADH Cytochrome b(5) Reductase from Pisum sativum.
Plant physiology 1987;85(2):457-62.
1987: M T Fisher; Stephen G Sligar
Temperature jump relaxation kinetics of the P-450cam spin equilibrium.
Biochemistry 1987;26(15):4797-803.
1986: S Beck von Bodman; M A Schuler; D R Jollie; Stephen G Sligar
Synthesis, bacterial expression, and mutagenesis of the gene coding for mammalian cytochrome b5.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(24):9443-7.
1986: O Bangcharoenpaurpong; Apostolos Rizos; Paul Champion; D Jollie; Stephen G Sligar
Resonance Raman detection of bound dioxygen in cytochrome P-450cam.
The Journal of biological chemistry 1986;261(18):8089-92.
1986: Y Y Huang; T Hara; Stephen G Sligar; M J Coon; T Kimura
Thermodynamic properties of oxidation-reduction reactions of bacterial, microsomal, and mitochondrial cytochromes P-450: an entropy-enthalpy compensation effect.
Biochemistry 1986;25(6):1390-4.
1986: B P Unger; I C Gunsalus; Stephen G Sligar
Nucleotide sequence of the Pseudomonas putida cytochrome P-450cam gene and its expression in Escherichia coli.
The Journal of biological chemistry 1986;261(3):1158-63.
1985: M T Fisher; Stephen G Sligar
Tyrosine motions in relation to the ferric spin equilibrium of cytochrome P-450cam.
Biochemistry 1985;24(23):6696-701.
1985: W L Backes; P P Tamburini; I Jansson; G G Gibson; Stephen G Sligar; John B Schenkman
Kinetics of cytochrome P-450 reduction: evidence for faster reduction of the high-spin ferric state.
Biochemistry 1985;24(19):5130-6.
1985: G Padbury; Stephen G Sligar
Chemical reactivities of bleomycin.
The Journal of biological chemistry 1985;260(13):7820-3.
1985: M T Fisher; S F Scarlata; Stephen G Sligar
High-pressure investigations of cytochrome P-450 spin and substrate binding equilibria.
Archives of biochemistry and biophysics 1985;240(1):456-63.
1985: J M Werneke; Stephen G Sligar; M A Schuler
Development of broad-host-range vectors for expression of cloned genes in Pseudomonas.
Gene 1985;38(1-3):73-84.
1985: S R Keyes; D C Heimbrook; P M Fracasso; S Rockwell; Stephen G Sligar; A C Sartorelli
Chemotherapeutic attack of hypoxic tumor cells by the bioreductive alkylating agent mitomycin C.
Advances in enzyme regulation 1985;23():291-307.
1984: S R Keyes; P M Fracasso; D C Heimbrook; S Rockwell; Stephen G Sligar; A C Sartorelli
Role of NADPH:cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C1.
Cancer research 1984;44(12 Pt 1):5638-43.
1984: P P Tamburini; G G Gibson; W L Backes; Stephen G Sligar; John B Schenkman
Reduction kinetics of purified rat liver cytochrome P-450. Evidence for a sequential reaction mechanism dependent on the hemoprotein spin state.
Biochemistry 1984;23(20):4526-33.
1984: R E White; M B McCarthy; K D Egeberg; Stephen G Sligar
Regioselectivity in the cytochromes P-450: control by protein constraints and by chemical reactivities.
Archives of biochemistry and biophysics 1984;228(2):493-502.
1984: Stephen G Sligar; M H Gelb; D C Heimbrook
Bio-organic chemistry and cytochrome P-450-dependent catalysis.
Xenobiotica; the fate of foreign compounds in biological systems 1984;14(1-2):63-86.
1983: B A Lewis; Stephen G Sligar
Structural studies of cytochrome P-450 using small angle x-ray scattering.
The Journal of biological chemistry 1983;258(6):3599-601.
1982: M H Gelb; W A Toscano; Stephen G Sligar
Chemical mechanisms for cytochrome P-450 oxidation: spectral and catalytic properties of a manganese-substituted protein.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(19):5758-62.
1982: K A Kennedy; Stephen G Sligar; L Polomski; A C Sartorelli
Metabolic activation of mitomycin C by liver microsomes and nuclei.
Biochemical pharmacology 1982;31(11):2011-6.
1982: W L Backes; Stephen G Sligar; John B Schenkman
Kinetics of hepatic cytochrome P-450 reduction: correlation with spin state of the ferric heme.
Biochemistry 1982;21(6):1324-30.
1982: M H Gelb; P Malkonen; Stephen G Sligar
Cytochrome P450cam catalyzed epoxidation of dehydrocamphor.
Biochemical and biophysical research communications 1982;104(3):853-8.
1982: M H Gelb; D C Heimbrook; P Mälkönen; Stephen G Sligar
Stereochemistry and deuterium isotope effects in camphor hydroxylation by the cytochrome P450cam monoxygenase system.
Biochemistry 1982;21(2):370-7.
1981: P E Cole; Stephen G Sligar
Temperature-jump measurement of the spin state relaxation rate of cytochrome P450cam.
FEBS letters 1981;133(2):252-4.
1981: P V Gould; M H Gelb; Stephen G Sligar
Interaction of 5-bromocamphor with cytochrome P-450 cam. Production of 5-ketocamphor from a mixed spin state hemoprotein.
The Journal of biological chemistry 1981;256(13):6686-91.
1981: D C Heimbrook; Stephen G Sligar
Multiple mechanisms of cytochrome P450-catalyzed substrate hydroxylations.
Biochemical and biophysical research communications 1981;99(2):530-5.
1981: J B Schenkman; Stephen G Sligar; D L Cinti
Substrate interaction with cytochrome P-450.
Pharmacology & therapeutics 1981;12(1):43-71.
1980: W L Backes; Stephen G Sligar; John B Schenkman
Cytochrome P-450 reduction exhibits burst kinetics.
Biochemical and biophysical research communications 1980;97(3):860-7.
1980: R E White; Stephen G Sligar; M J Coon
Evidence for a homolytic mechanism of peroxide oxygen--oxygen bond cleavage during substrate hydroxylation by cytochrome P-450.
The Journal of biological chemistry 1980;255(23):11108-11.
1980: G G Gibson; D L Cinti; Stephen G Sligar; J B Schenkman
The effect of microsomal fatty acids and other lipids on the spin state of partially purified cytochrome P-450.
The Journal of biological chemistry 1980;255(5):1867-73.
1980: Stephen G Sligar; K A Kennedy; D C Pearson
Chemical mechanisms for cytochrome P-450 hydroxylation: evidence for acylation of heme-bound dioxygen.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(3):1240-4.
1980: J B Henes; M S Briggs; Stephen G Sligar; J S Fruton
Fluorescence energy transfer studies on the active site of papain.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(2):940-3.
1980: G G Gibson; Stephen G Sligar; D L Cinti; J B Schenkman
Purified cytochrome P-450: spin-state control of the haemoprotein redox potential [proceedings].
Biochemical Society transactions 1980;8(1):101-2.
1979: G G Gibson; D L Cinti; Stephen G Sligar; J B Schenkman
The effect of microsomal lipids on the spin state of purified de-lipidated cytochrome P-450 [proceedings].
Biochemical Society transactions 1979;7(6):1289-90.
1979: Stephen G Sligar; D L Cinti; G G Gibson; J B Schenkman
Spin state control of the hepatic cytochrome P450 redox potential.
Biochemical and biophysical research communications 1979;90(3):925-32.
1979: Stephen G Sligar
A thermoelectric cuvette cooler for optical studies in cryobiochemistry.
Cryobiology 1979;16(5):506-8.
1979: Stephen G Sligar; I C Gunsalus
Proton coupling in the cytochrome P-450 spin and redox equilibria.
Biochemistry 1979;18(11):2290-5.
1979: D L Cinti; Stephen G Sligar; G G Gibson; J B Schenkman
Temperature-dependent spin equilibrium of microsomal and solubilized cytochrome P-450 from rat liver.
Biochemistry 1979;18(1):36-42.
1978: I C Gunsalus; Stephen G Sligar
Oxygen reduction by the P450 monoxygenase systems.
Advances in enzymology and related areas of molecular biology 1978;47():1-44.
1977: I C Gunsalus; Stephen G Sligar; T Nordlund; H Frauenfelder
Oxygen sensing heme proteins: monoxygenases, myoglobin and hemoglobin.
Advances in experimental medicine and biology 1977;78():37-50.
1976: Stephen G Sligar
Coupling of spin, substrate, and redox equilibria in cytochrome P450.
Biochemistry 1976;15(24):5399-406.
1976: L K Hanson; William Eaton; Stephen G Sligar; I C Gunsalus; M Gouterman; C R Connell
Letter: Origin of the anomalous Soret spectra of carboxycytochrome P-450.
Journal of the American Chemical Society 1976;98(9):2672-4.
1976: Stephen G Sligar; I C Gunsalus
A thermodynamic model of regulation: modulation of redox equilibria in camphor monoxygenase.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(4):1078-82.
1976: J D Lipscomb; Stephen G Sligar; M J Namtvedt; I C Gunsalus
Autooxidation and hydroxylation reactions of oxygenated cytochrome P-450cam.
The Journal of biological chemistry 1976;251(4):1116-24.
1976: I C Gunsalus; Stephen G Sligar
Redox regulation of cytochrome P450cam mixed function oxidation by putidaredoxin and camphor ligation.
Biochimie 1976;58(1-2):143-7.
1976: I C Gunsalus; Stephen G Sligar
Equilibrium states and dynamic reactions of iron in the camphor monoxygenase system.
Advances in experimental medicine and biology 1976;74():254-62.
1975: I C Gunsalus; T C Pederson; Stephen G Sligar
Oxygenase-catalyzed biological hydroxylations.
Annual review of biochemistry 1975;44():377-407.
1974: Stephen G Sligar; J D Lipscomb; P G Debrunner; I C Gunsalus
Superoxide anion production by the autoxidation of cytochrome P450cam.
Biochemical and biophysical research communications 1974;61(1):290-6.
1974: Stephen G Sligar; P G Debrunner; J D Lipscomb; M J Namtvedt; I C Gunsalus
A role of the putidaredoxin COOH-terminus in P-450cam (cytochrome m) hydroxylations.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(10):3906-10.