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Caroline Small

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Nina M Semjonous; Kirsty L Smith; James R C Parkinson; D J L Gunner; Y-L Liu; Kevin G Murphy; Mohammad A Ghatei; Stephen R Bloom; Caroline J Small
Coordinated changes in energy intake and expenditure following hypothalamic administration of neuropeptides involved in energy balance.
James R C Parkinson; Waljit S Dhillo; Caroline J Small; Owais B Chaudhri; Gavin A Bewick; Iain Pritchard; Stanley Moore; Mohammed A Ghatei; Stephen R Bloom
PYY3-36 injection in mice produces an acute anorexigenic effect followed by a delayed orexigenic effect not observed with other anorexigenic gut hormones.
Nicholas E White; Waljit S Dhillo; Y-L Liu; Caroline J Small; G A Kennett; James V Gardiner; Mohammad A Ghatei; Stephen R Bloom
Co-administration of SR141716 with peptide YY3-36 or oxyntomodulin has additive effects on food intake in mice.

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2009: Nina M Semjonous; Kirsty L Smith; James R C Parkinson; D J L Gunner; Y-L Liu; Kevin G Murphy; Mohammad A Ghatei; Stephen R Bloom; Caroline J Small
Coordinated changes in energy intake and expenditure following hypothalamic administration of neuropeptides involved in energy balance.
International journal of obesity (2005) 2009;33(7):775-85.
2008: James R C Parkinson; Waljit S Dhillo; Caroline J Small; Owais B Chaudhri; Gavin A Bewick; Iain Pritchard; Stanley Moore; Mohammed A Ghatei; Stephen R Bloom
PYY3-36 injection in mice produces an acute anorexigenic effect followed by a delayed orexigenic effect not observed with other anorexigenic gut hormones.
American journal of physiology. Endocrinology and metabolism 2008;294(4):E698-708.
2008: Nicholas E White; Waljit S Dhillo; Y-L Liu; Caroline J Small; G A Kennett; James V Gardiner; Mohammad A Ghatei; Stephen R Bloom
Co-administration of SR141716 with peptide YY3-36 or oxyntomodulin has additive effects on food intake in mice.
Diabetes, obesity & metabolism 2008;10(2):167-70.
2007: Yu-Ting Kuo; James R C Parkinson; Owais B Chaudhri; Amy H Herlihy; Po-Wah So; Waljit S Dhillo; Caroline J Small; Stephen R Bloom; Jimmy D Bell
The temporal sequence of gut peptide CNS interactions tracked in vivo by magnetic resonance imaging.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(45):12341-8.
2007: Niamh M Martin; Caroline J Small; J L Lee; S Ellis; Waljit S Dhillo; Kirsty L Smith; Wing May Kong; Gary S Frost; Stephen R Bloom
Low-dose oral tri-iodothyronine does not directly increase food intake in man.
Diabetes, obesity & metabolism 2007;9(3):435-7.
2007: David R Jesudason; Mariana P Monteiro; B M C McGowan; Nicola M Neary; Adrian J Park; Elena Philippou; Caroline J Small; Gary S Frost; Mohammad A Ghatei; Stephen R Bloom
Low-dose pancreatic polypeptide inhibits food intake in man.
The British journal of nutrition 2007;97(3):426-9.
2006: Katie Wynne; Adrian J Park; Caroline J Small; Karim Meeran; Mohammad A Ghatei; Gary S Frost; Stephen R Bloom
Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in overweight and obese humans: a randomised controlled trial.
International journal of obesity (2005) 2006;30(12):1729-36.
2006: B M C McGowan; Sarah A Stanley; Kirsty L Smith; J S Minnion; J Donovan; Emily L Thompson; Michael Patterson; M M Connolly; Caroline R Abbott; Caroline J Small; James V Gardiner; Mohammad A Ghatei; Stephen R Bloom
Effects of acute and chronic relaxin-3 on food intake and energy expenditure in rats.
Regulatory peptides 2006;136(1-3):72-7.
2006: Preeti Jethwa; Kirsty L Smith; Caroline J Small; Caroline R Abbott; Sarah J Darch; Kevin G Murphy; Asha Seth; Nina M Semjonous; Sejal R Patel; Jeannie F Todd; Mohammad A Ghatei; Stephen R Bloom
Neuromedin U partially mediates leptin-induced hypothalamo-pituitary adrenal (HPA) stimulation and has a physiological role in the regulation of the HPA axis in the rat.
Endocrinology 2006;147(6):2886-92.
2006: Niamh M Martin; Pamela A Houston; Michael Patterson; Arshia Sajedi; D F Carmignac; Mohammad A Ghatei; Stephen R Bloom; Caroline J Small
Abnormalities of the somatotrophic axis in the obese agouti mouse.
International journal of obesity (2005) 2006;30(3):430-8.
2006: Niamh M Martin; Kirsty L Smith; Stephen R Bloom; Caroline J Small
Interactions between the melanocortin system and the hypothalamo-pituitary-thyroid axis.
Peptides 2006;27(2):333-9.
2006: Maralyn R Druce; Nicola M Neary; Caroline J Small; J Milton; M Monteiro; Michael Patterson; Mohammad A Ghatei; Stephen R Bloom
Subcutaneous administration of ghrelin stimulates energy intake in healthy lean human volunteers.
International journal of obesity (2005) 2006;30(2):293-6.
2006: Caroline R Abbott; Caroline J Small; Arshia Sajedi; Kirsty L Smith; James R C Parkinson; L L Broadhead; Mohammad A Ghatei; Stephen R Bloom
The importance of acclimatisation and habituation to experimental conditions when investigating the anorectic effects of gastrointestinal hormones in the rat.
International journal of obesity (2005) 2006;30(2):288-92.
2006: Nicola M Neary; Maralyn R Druce; Caroline J Small; Stephen R Bloom
Acylated ghrelin stimulates food intake in the fed and fasted states but desacylated ghrelin has no effect.
Gut 2006;55(1):135.
2005: Nicola M Neary; Caroline J Small; Maralyn R Druce; Adrian J Park; Sandra M Ellis; Nina M Semjonous; Catherine L Dakin; Karin Filipsson; Fang Wang; Aysha S Kent; Gary S Frost; Mohammad A Ghatei; Stephen R Bloom
Peptide YY3-36 and glucagon-like peptide-17-36 inhibit food intake additively.
Endocrinology 2005;146(12):5120-7.
2005: Katie Wynne; Adrian J Park; Caroline J Small; Michael Patterson; Sandra M Ellis; Kevin G Murphy; Alison M Wren; Gary S Frost; Karim Meeran; Mohammad A Ghatei; Stephen R Bloom
Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects: a double-blind, randomized, controlled trial.
Diabetes 2005;54(8):2390-5.
2005: Preeti Jethwa; Caroline J Small; Kirsty L Smith; Asha Seth; Sarah J Darch; Caroline R Abbott; Kevin G Murphy; Jeannie F Todd; Mohammad A Ghatei; Stephen R Bloom
Neuromedin U has a physiological role in the regulation of food intake and partially mediates the effects of leptin.
American journal of physiology. Endocrinology and metabolism 2005;289(2):E301-5.
2005: Carel W le Roux; Nicola M Neary; T J Halsey; Caroline J Small; A M Martinez-Isla; Mohammad A Ghatei; N A Theodorou; Stephen R Bloom
Ghrelin does not stimulate food intake in patients with surgical procedures involving vagotomy.
The Journal of clinical endocrinology and metabolism 2005;90(8):4521-4.
2005: Caroline R Abbott; Mariana Monteiro; Caroline J Small; Arshia Sajedi; Kirsty L Smith; James R C Parkinson; Mohammad A Ghatei; Stephen R Bloom
The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway.
Brain research 2005;1044(1):127-31.
2005: Caroline R Abbott; Caroline J Small; Adam R Kennedy; Nicola M Neary; Arshia Sajedi; Mohammad A Ghatei; Stephen R Bloom
Blockade of the neuropeptide Y Y2 receptor with the specific antagonist BIIE0246 attenuates the effect of endogenous and exogenous peptide YY(3-36) on food intake.
Brain research 2005;1043(1-2):139-44.
2005: Caroline J Small; Stephen R Bloom
The therapeutic potential of gut hormone peptide YY3-36 in the treatment of obesity.
Expert opinion on investigational drugs 2005;14(5):647-53.
2005: Ulrika Andersson; Jonas T Treebak; Jakob N Nielsen; Kirsty L Smith; Caroline R Abbott; Caroline J Small; David Carling; Erik A Richter
Exercise in rats does not alter hypothalamic AMP-activated protein kinase activity.
Biochemical and biophysical research communications 2005;329(2):719-25.
2005: Caroline J Small; James R C Parkinson; Stephen R Bloom
Novel therapeutic targets for appetite regulation.
Current opinion in investigational drugs (London, England : 2000) 2005;6(4):369-72.
2004: Niamh M Martin; Caroline J Small; Arshia Sajedi; Xiao H Liao; Roy E Weiss; James V Gardiner; Mohammad A Ghatei; Stephen R Bloom
Abnormalities of the hypothalamo-pituitary-thyroid axis in the pro-opiomelanocortin deficient mouse.
Regulatory peptides 2004;122(3):169-72.
2004: Wing May Kong; Niamh M Martin; Kirsty L Smith; James V Gardiner; Ian P Connoley; David A Stephens; Waljit S Dhillo; Mohammad A Ghatei; Caroline J Small; Stephen R Bloom
Triiodothyronine stimulates food intake via the hypothalamic ventromedial nucleus independent of changes in energy expenditure.
Endocrinology 2004;145(11):5252-8.
2004: Emily L Thompson; Kevin G Murphy; Jeannie F Todd; Niamh M Martin; Caroline J Small; Mohammad A Ghatei; Stephen R Bloom
Chronic administration of NMU into the paraventricular nucleus stimulates the HPA axis but does not influence food intake or body weight.
Biochemical and biophysical research communications 2004;323(1):65-71.
2004: Caroline J Small; Stephen R Bloom
Gut hormones as peripheral anti obesity targets.
Current drug targets. CNS and neurological disorders 2004;3(5):379-88.
2004: Sarah A Stanley; Kevin G Murphy; Gavin A Bewick; Wing May Kong; Jolanta Opacka-Juffry; James V Gardiner; Mohammad A Ghatei; Caroline J Small; Stephen R Bloom
Regulation of rat pituitary cocaine- and amphetamine-regulated transcript (CART) by CRH and glucocorticoids.
American journal of physiology. Endocrinology and metabolism 2004;287(3):E583-90.
2004: Caroline J Small; Stephen R Bloom
Gut hormones and the control of appetite.
Trends in endocrinology and metabolism: TEM 2004;15(6):259-63.
2004: Niamh M Martin; Caroline J Small; Arshia Sajedi; Michael Patterson; Mohammad A Ghatei; Stephen R Bloom
Pre-obese and obese agouti mice are sensitive to the anorectic effects of peptide YY(3-36) but resistant to ghrelin.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2004;28(7):886-93.
2004: Nicola M Neary; Caroline J Small; Alison M Wren; Jennifer L Lee; Maralyn R Druce; Carlo Palmieri; Gary S Frost; Mohammad A Ghatei; R Charles Coombes; Stephen R Bloom
Ghrelin increases energy intake in cancer patients with impaired appetite: acute, randomized, placebo-controlled trial.
The Journal of clinical endocrinology and metabolism 2004;89(6):2832-6.
2004: Maralyn R Druce; Caroline J Small; Stephen R Bloom
Minireview: Gut peptides regulating satiety.
Endocrinology 2004;145(6):2660-5.
2004: Catherine L Dakin; Caroline J Small; Rachel L Batterham; Nicola M Neary; Mark A Cohen; Michael Patterson; Mohammad A Ghatei; Stephen R Bloom
Peripheral oxyntomodulin reduces food intake and body weight gain in rats.
Endocrinology 2004;145(6):2687-95.
2004: Ulrika Andersson; Karin Filipsson; Caroline R Abbott; Angela Woods; Kirsty Smith; Stephen R Bloom; David Carling; Caroline J Small
AMP-activated protein kinase plays a role in the control of food intake.
The Journal of biological chemistry 2004;279(13):12005-8.
2003: Caroline R Abbott; Adam R Kennedy; Alison M Wren; Michela Rossi; Kevin G Murphy; Leighton J Seal; Jeannie F Todd; Mohammad A Ghatei; Caroline J Small; Stephen R Bloom
Identification of hypothalamic nuclei involved in the orexigenic effect of melanin-concentrating hormone.
Endocrinology 2003;144(9):3943-9.
2003: Nicola M Neary; Caroline J Small; Stephen R Bloom
Gut and mind.
Gut 2003;52(7):918-21.
2003: Sarah A Stanley; S Davies; Caroline J Small; James V Gardiner; Mohammad A Ghatei; David M Smith; Stephen R Bloom
gamma-MSH increases intracellular cAMP accumulation and GnRH release in vitro and LH release in vivo.
FEBS letters 2003;543(1-3):66-70.
2003: Caroline J Small; Yong-Ling Liu; S A Stanley; Ian P Connoley; A Kennedy; Michael J Stock; Stephen R Bloom
Chronic CNS administration of Agouti-related protein (Agrp) reduces energy expenditure.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2003;27(4):530-3.
2003: Waljit S Dhillo; Caroline J Small; Preeti Jethwa; Sabina H Russell; James V Gardiner; Gavin A Bewick; Asha Seth; Kevin G Murphy; Mohammad A Ghatei; Stephen R Bloom
Paraventricular nucleus administration of calcitonin gene-related peptide inhibits food intake and stimulates the hypothalamo-pituitary-adrenal axis.
Endocrinology 2003;144(4):1420-5.
2003: Waljit S Dhillo; Caroline J Small; James V Gardiner; Gavin A Bewick; EJ Whitworth; Preeti Jethwa; Leighton J Seal; Mohammad A Ghatei; Joy P Hinson; Stephen R Bloom
Agouti-related protein has an inhibitory paracrine role in the rat adrenal gland.
Biochemical and biophysical research communications 2003;301(1):102-7.
2002: Catherine L Dakin; Caroline J Small; Adrian J Park; Asha Seth; Mohammad A Ghatei; Stephen R Bloom
Repeated ICV administration of oxyntomodulin causes a greater reduction in body weight gain than in pair-fed rats.
American journal of physiology. Endocrinology and metabolism 2002;283(6):E1173-7.
2002: Andrea Bacon; Fiona E Holmes; Caroline J Small; Mohammad A Ghatei; Sally-Ann Mahoney; Steve Bloom; David Wynick
Transgenic over-expression of galanin in injured primary sensory neurons.
Neuroreport 2002;13(16):2129-32.
2002: Caroline J Small; S A Stanley; Stephen R Bloom
Appetite control and reproduction: leptin and beyond.
Seminars in reproductive medicine 2002;20(4):389-98.
2002: Alison M Wren; Caroline J Small; Charlotte V Fribbens; Nicola M Neary; Helen L Ward; Leighton J Seal; Mohammad A Ghatei; Stephen R Bloom
The hypothalamic mechanisms of the hypophysiotropic action of ghrelin.
Neuroendocrinology 2002;76(5):316-24.
2002: Alison M Wren; Caroline J Small; Caroline R Abbott; Preeti Jethwa; Adam R Kennedy; Kevin G Murphy; Sarah A Stanley; A N Zollner; Mohammad A Ghatei; Stephen R Bloom
Hypothalamic actions of neuromedin U.
Endocrinology 2002;143(11):4227-34.
2002: Waljit S Dhillo; Caroline J Small; Sarah A Stanley; Preeti Jethwa; Leighton J Seal; Kevin G Murphy; Mohammad A Ghatei; Stephen R Bloom
Hypothalamic interactions between neuropeptide Y, agouti-related protein, cocaine- and amphetamine-regulated transcript and alpha-melanocyte-stimulating hormone in vitro in male rats.
Journal of neuroendocrinology 2002;14(9):725-30.
2002: Rachel L Batterham; Michael Alexander cowley; Caroline J Small; Herbert Herzog; Mark A Cohen; Catherine L Dakin; Alison M Wren; Audrey E Brynes; Malcolm J Low; Mohammad A Ghatei; Roger D Cone; Stephen R Bloom
Gut hormone PYY(3-36) physiologically inhibits food intake.
Nature 2002;418(6898):650-4.
2002: Leighton J Seal; Caroline J Small; Waljit S Dhillo; Adam R Kennedy; Mohammad A Ghatei; Stephen R Bloom
Prolactin-releasing peptide releases corticotropin-releasing hormone and increases plasma adrenocorticotropin via the paraventricular nucleus of the hypothalamus.
Neuroendocrinology 2002;76(2):70-8.
2002: Waljit S Dhillo; Caroline J Small; Leighton J Seal; Min-Seon Kim; Sarah A Stanley; Kevin G Murphy; Mohammad A Ghatei; Stephen R Bloom
The hypothalamic melanocortin system stimulates the hypothalamo-pituitary-adrenal axis in vitro and in vivo in male rats.
Neuroendocrinology 2002;75(4):209-16.
2002: Min-Seon Kim; Caroline J Small; Sabina H Russell; D G A Morgan; Caroline R Abbott; Samaher AlAhmed; D L Hay; Mohammad A Ghatei; David M Smith; Stephen R Bloom
Effects of melanocortin receptor ligands on thyrotropin-releasing hormone release: evidence for the differential roles of melanocortin 3 and 4 receptors.
Journal of neuroendocrinology 2002;14(4):276-82.
2002: Sabina H Russell; Caroline J Small; D Sunter; I Morgan; Catherine L Dakin; Mark A Cohen; Stephen R Bloom
Chronic intraparaventricular nuclear administration of orexin A in male rats does not alter thyroid axis or uncoupling protein-1 in brown adipose tissue.
Regulatory peptides 2002;104(1-3):61-8.
2001: Sabina H Russell; Caroline J Small; Adam R Kennedy; Sarah A Stanley; Asha Seth; Kevin G Murphy; Shahrad Taheri; Mohammad A Ghatei; Stephen R Bloom
Orexin A interactions in the hypothalamo-pituitary gonadal axis.
Endocrinology 2001;142(12):5294-302.
2001: Alison M Wren; Caroline J Small; Caroline R Abbott; Waljit S Dhillo; Leighton J Seal; Mark A Cohen; Rachel L Batterham; Shahrad Taheri; Sarah A Stanley; Mohammad A Ghatei; Stephen R Bloom
Ghrelin causes hyperphagia and obesity in rats.
Diabetes 2001;50(11):2540-7.
2001: Catherine L Dakin; I Gunn; Caroline J Small; C Mark Edwards; D L Hay; David M Smith; Mohammad A Ghatei; Stephen R Bloom
Oxyntomodulin inhibits food intake in the rat.
Endocrinology 2001;142(10):4244-50.
2001: Leighton J Seal; Caroline J Small; Waljit S Dhillo; Sarah A Stanley; Caroline R Abbott; Mohammad A Ghatei; Stephen R Bloom
PRL-releasing peptide inhibits food intake in male rats via the dorsomedial hypothalamic nucleus and not the paraventricular hypothalamic nucleus.
Endocrinology 2001;142(10):4236-43.
2001: Caroline R Abbott; Michela Rossi; Alison M Wren; Kevin G Murphy; Adam R Kennedy; Sarah A Stanley; A N Zollner; D G A Morgan; I Morgan; Mohammad A Ghatei; Caroline J Small; Stephen R Bloom
Evidence of an orexigenic role for cocaine- and amphetamine-regulated transcript after administration into discrete hypothalamic nuclei.
Endocrinology 2001;142(8):3457-63.
2001: Helen L Ward; Caroline J Small; Kevin G Murphy; Adam R Kennedy; Mohammad A Ghatei; Stephen R Bloom
The actions of tuberoinfundibular peptide on the hypothalamo-pituitary axes.
Endocrinology 2001;142(8):3451-6.
2001: Adam R Kennedy; Jeannie F Todd; Sarah A Stanley; Caroline R Abbott; Caroline J Small; Mohammad A Ghatei; S R Bloom
Melanin-concentrating hormone (MCH) suppresses thyroid stimulating hormone (TSH) release, in vivo and in vitro, via the hypothalamus and the pituitary.
Endocrinology 2001;142(7):3265-8.
2001: Sabina H Russell; Caroline J Small; Catherine L Dakin; Caroline R Abbott; D G A Morgan; Mohammad A Ghatei; Stephen R Bloom
The central effects of orexin-A in the hypothalamic-pituitary-adrenal axis in vivo and in vitro in male rats.
Journal of neuroendocrinology 2001;13(6):561-6.
2001: Sarah A Stanley; Caroline J Small; Kevin G Murphy; E Rayes; Caroline R Abbott; Leighton J Seal; D G A Morgan; D Sunter; Catherine L Dakin; Min-Seon Kim; R Hunter; Michael J Kuhar; Mohammad A Ghatei; Stephen R Bloom
Actions of cocaine- and amphetamine-regulated transcript (CART) peptide on regulation of appetite and hypothalamo-pituitary axes in vitro and in vivo in male rats.
Brain research 2001;893(1-2):186-94.
2001: Sabina H Russell; Caroline J Small; Sarah A Stanley; S Franks; Mohammad A Ghatei; Stephen R Bloom
The in vitro role of tumour necrosis factor-alpha and interleukin-6 in the hypothalamic-pituitary gonadal axis.
Journal of neuroendocrinology 2001;13(3):296-301.
2001: Caroline J Small; Min-Seon Kim; Sarah A Stanley; J R Mitchell; K Murphy; D G A Morgan; Mohammad A Ghatei; Stephen R Bloom
Effects of chronic central nervous system administration of agouti-related protein in pair-fed animals.
Diabetes 2001;50(2):248-54.
2000: Sabina H Russell; Min-Seon Kim; Caroline J Small; Caroline R Abbott; D G A Morgan; Shahrad Taheri; Kevin G Murphy; Jeannie F Todd; Mohammad A Ghatei; Stephen R Bloom
Central administration of orexin A suppresses basal and domperidone stimulated plasma prolactin.
Journal of neuroendocrinology 2000;12(12):1213-8.
2000: Alison M Wren; Caroline J Small; Helen L Ward; Kevin G Murphy; Catherine L Dakin; Shahrad Taheri; Adam R Kennedy; G H Roberts; D G A Morgan; Mohammad A Ghatei; Stephen R Bloom
The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion.
Endocrinology 2000;141(11):4325-8.
2000: Sarah A Stanley; Jeannie F Todd; Caroline J Small; Min-Seon Kim; MM Heath; Praveen Anand; Mohammad A Ghatei; Stephen R Bloom
The effects of ciliary neurotrophic factor on the hypothalamo-pituitary gonadal axis in vitro in female rats.
Journal of neuroendocrinology 2000;12(10):1009-13.
2000: Leighton J Seal; Caroline J Small; Min-Seon Kim; Sarah A Stanley; Shahrad Taheri; Mohammad A Ghatei; Stephen R Bloom
Prolactin releasing peptide (PrRP) stimulates luteinizing hormone (LH) and follicle stimulating hormone (FSH) via a hypothalamic mechanism in male rats.
Endocrinology 2000;141(5):1909-12.
2000: Min-Seon Kim; Caroline J Small; Sarah A Stanley; D G A Morgan; Leighton J Seal; Wing May Kong; C Mark Edwards; S Abusnana; D Sunter; Mohammad A Ghatei; Stephen R Bloom
The central melanocortin system affects the hypothalamo-pituitary thyroid axis and may mediate the effect of leptin.
The Journal of clinical investigation 2000;105(7):1005-11.
2000: F Satoh; SA Beak; Caroline J Small; M Falzon; Mohammad A Ghatei; Stephen R Bloom; David M Smith
Characterization of human and rat glucagon-like peptide-1 receptors in the neurointermediate lobe: lack of coupling to either stimulation or inhibition of adenylyl cyclase.
Endocrinology 2000;141(4):1301-9.
2000: Min-Seon Kim; Michela Rossi; S Abusnana; D Sunter; D G A Morgan; Caroline J Small; C Mark Edwards; MM Heath; Sarah A Stanley; Leighton J Seal; J R Bhatti; David M Smith; Mohammad A Ghatei; Stephen R Bloom
Hypothalamic localization of the feeding effect of agouti-related peptide and alpha-melanocyte-stimulating hormone.
Diabetes 2000;49(2):177-82.
1999: Michela Rossi; SA Beak; SJ Choi; Caroline J Small; D G A Morgan; Mohammad A Ghatei; David M Smith; Stephen R Bloom
Investigation of the feeding effects of melanin concentrating hormone on food intake--action independent of galanin and the melanocortin receptors.
Brain research 1999;846(2):164-70.
1999: Sarah A Stanley; Caroline J Small; Min-Seon Kim; MM Heath; Leighton J Seal; Sabina H Russell; Mohammad A Ghatei; Stephen R Bloom
Agouti related peptide (Agrp) stimulates the hypothalamo pituitary gonadal axis in vivo & in vitro in male rats.
Endocrinology 1999;140(11):5459-62.
1999: Karim Meeran; D O'Shea; C Mark Edwards; MD Turton; MM Heath; I Gunn; S Abusnana; Michela Rossi; Caroline J Small; Anthony P Goldstone; GM Taylor; D Sunter; J Steere; SJ Choi; Mohammad A Ghatei; Stephen R Bloom
Repeated intracerebroventricular administration of glucagon-like peptide-1-(7-36) amide or exendin-(9-39) alters body weight in the rat.
Endocrinology 1999;140(1):244-50.
1998: David Wynick; Caroline J Small; S R Bloom; Vassilis Pachnis
Targeted disruption of the murine galanin gene.
Annals of the New York Academy of Sciences 1998;863():22-47.
1998: David Wynick; Caroline J Small; Andrea Bacon; Fiona E Holmes; M Norman; Christopher J Ormandy; E Kilic; Niall C H Kerr; Mohammad A Ghatei; F Talamantes; S R Bloom; Vassilis Pachnis
Galanin regulates prolactin release and lactotroph proliferation.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(21):12671-6.
1998: Michela Rossi; Min-Seon Kim; D G A Morgan; Caroline J Small; C Mark Edwards; D Sunter; S Abusnana; Anthony P Goldstone; Sabina H Russell; Sarah A Stanley; David M Smith; K Yagaloff; Mohammad A Ghatei; Stephen R Bloom
A C-terminal fragment of Agouti-related protein increases feeding and antagonizes the effect of alpha-melanocyte stimulating hormone in vivo.
Endocrinology 1998;139(10):4428-31.
1998: Jeannie F Todd; Caroline J Small; Karen Akinsanya; Sarah A Stanley; David M Smith; Stephen R Bloom
Galanin is a paracrine inhibitor of gonadotroph function in the female rat.
Endocrinology 1998;139(10):4222-9.
1998: D G A Morgan; Caroline J Small; S Abusnana; MD Turton; I Gunn; M Heath; Michela Rossi; Anthony P Goldstone; D O'Shea; Karim Meeran; Mohammad A Ghatei; David M Smith; Steve Bloom
The NPY Y1 receptor antagonist BIBP 3226 blocks NPY induced feeding via a non-specific mechanism.
Regulatory peptides 1998;75-76():377-82.
1998: Caroline J Small; Jeannie F Todd; Mohammad A Ghatei; David M Smith; Stephen R Bloom
Neuropeptide Y (NPY) actions on the corticotroph cell of the anterior pituitary gland are not mediated by a direct effect.
Regulatory peptides 1998;75-76():301-7.
1998: SA Beak; MM Heath; Caroline J Small; D G A Morgan; Mohammad A Ghatei; AD Taylor; Julia C Buckingham; Stephen R Bloom; David M Smith
Glucagon-like peptide-1 stimulates luteinizing hormone-releasing hormone secretion in a rodent hypothalamic neuronal cell line.
The Journal of clinical investigation 1998;101(6):1334-41.
1997: Caroline J Small; D G A Morgan; Karim Meeran; MM Heath; I Gunn; C Mark Edwards; J Gardiner; GM Taylor; JD Hurley; Michela Rossi; Anthony P Goldstone; D O'Shea; David M Smith; Mohammad A Ghatei; Stephen R Bloom
Peptide analogue studies of the hypothalamic neuropeptide Y receptor mediating pituitary adrenocorticotrophic hormone release.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(21):11686-91.
1997: Karim Meeran; D O'Shea; P D Upton; Caroline J Small; Mohammad A Ghatei; P H Byfield; Stephen R Bloom
Circulating adrenomedullin does not regulate systemic blood pressure but increases plasma prolactin after intravenous infusion in humans: a pharmacokinetic study.
The Journal of clinical endocrinology and metabolism 1997;82(1):95-100.
1997: D O'Shea; D G A Morgan; Karim Meeran; C Mark Edwards; MD Turton; SJ Choi; MM Heath; I Gunn; GM Taylor; Jane K Howard; C I Bloom; Caroline J Small; O Haddo; J J Ma; W Callinan; David M Smith; Mohammad A Ghatei; Stephen R Bloom
Neuropeptide Y induced feeding in the rat is mediated by a novel receptor.
Endocrinology 1997;138(1):196-202.
1996: S A Beak; Caroline J Small; I Ilovaiskaia; J D Hurley; Mohammad A Ghatei; Stephen R Bloom; David M Smith
Glucagon-like peptide-1 (GLP-1) releases thyrotropin (TSH): characterization of binding sites for GLP-1 on alpha-TSH cells.
Endocrinology 1996;137(10):4130-8.