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Bård Smedsrød

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Dmitri Svistounov; Svetlana N Zykova; Karen Kristine Sørensen; Peter A G McCourt; Robert S McCuskey; Andrew J McLachlan; Ana Oteiza; Bård Smedsrød
Hepatic disposal of advanced glycation end products during maturation and aging.
Karen Kristine Sørensen; Kenjiro Wake; David Le Couteur; Trond Berg; Clive Crossley; Peter McCourt; Bård Smedsrød
The scavenger endothelial cell: a new player in homeostasis and immunity.
Dmitri Svistounov; Alessandra Warren; Dusan Zencak; Svetlana N Zykova; Harry Crane; Thomas Huser; David G Le Couteur; Gregory P McNerney; Dylan M Owen; Ronald J Quinn; Bård Smedsrød; Victoria C Cogger
The Relationship between fenestrations, sieve plates and rafts in liver sinusoidal endothelial cells.

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2013: Dmitri Svistounov; Svetlana N Zykova; Karen Kristine Sørensen; Peter A G McCourt; Robert S McCuskey; Andrew J McLachlan; Ana Oteiza; Bård Smedsrød
Hepatic disposal of advanced glycation end products during maturation and aging.
Experimental gerontology 2013;48(6):549-56.
2012: Karen Kristine Sørensen; Kenjiro Wake; David Le Couteur; Trond Berg; Clive Crossley; Peter McCourt; Bård Smedsrød
The scavenger endothelial cell: a new player in homeostasis and immunity.
American journal of physiology. Regulatory, integrative and comparative physiology 2012;303(12):R1217-30.
2012: Dmitri Svistounov; Alessandra Warren; Dusan Zencak; Svetlana N Zykova; Harry Crane; Thomas Huser; David G Le Couteur; Gregory P McNerney; Dylan M Owen; Ronald J Quinn; Bård Smedsrød; Victoria C Cogger
The Relationship between fenestrations, sieve plates and rafts in liver sinusoidal endothelial cells.
PloS one 2012;7(9):e46134.
2011: Cristina Ionica Øie; Helle Heibroch Petersen; Bård Smedsrød; Rupa Shree Appa; Albrecht Gruhler; Ida Hilden; John-Bjarne Hansen
Rat liver sinusoidal endothelial cells (LSECs) express functional low density lipoprotein receptor-related protein-1 (LRP-1).
Journal of hepatology 2011;55(6):1346-52.
2011: Ana Oteiza; Bård Smedsrød; Ruomei Li; Robert S McCuskey; Karen Kristine Sørensen
Effects of oxidized low-density lipoproteins on the hepatic microvasculature.
American journal of physiology. Gastrointestinal and liver physiology 2011;301(4):G684-93.
2011: Petter K Risøe; Arkady Rutkovskiy; Una Ryg; Bård Smedsrød; Guro Valen; Yun Yong Wang; Maria K Dahle
Cecal ligation and puncture sepsis is associated with attenuated expression of adenylyl cyclase 9 and increased miR142-3p.
Shock (Augusta, Ga.) 2011;36(4):390-5.
2011: Ruomei Li; Ana Oteiza; Karen Kristine Sørensen; Peter A G McCourt; Randi Olsen; Bård Smedsrød; Dmitri Svistounov
Role of liver sinusoidal endothelial cells and stabilins in elimination of oxidized low-density lipoproteins.
American journal of physiology. Gastrointestinal and liver physiology 2011;300(1):G71-81.
2010: Jaione Simon-Santamaria; Ivana Malovic; Alessandra Warren; Ana Oteiza; DAVID LE COUTEUR; Bård Smedsrød; Peter A G McCourt; Karen Kristine Sørensen
Age-related changes in scavenger receptor-mediated endocytosis in rat liver sinusoidal endothelial cells.
The journals of gerontology. Series A, Biological sciences and medical sciences 2010;65(9):951-60.
2010: Victoria C Cogger; Gregory P McNerney; Tun Nyunt; Laurie D DeLeve; Peter McCourt; Bård Smedsrød; David G Le Couteur; Thomas Huser
Three-dimensional structured illumination microscopy of liver sinusoidal endothelial cell fenestrations.
Journal of structural biology 2010;171(3):382-8.
2010: Beatriz Arteta; Nerea Lasuen; Aritz Lopategi; Baldur Sveinbjörnsson; Bård Smedsrød; Fernando Vidal-Vanaclocha
Colon carcinoma cell interaction with liver sinusoidal endothelium inhibits organ-specific antitumor immunity through interleukin-1-induced mannose receptor in mice.
Hepatology (Baltimore, Md.) 2010;51(6):2172-82.
2009: Hong Qian; Sophie Johansson; Peter McCourt; Bård Smedsrød; Marja Ekblom; Staffan Johansson
Stabilins are expressed in bone marrow sinusoidal endothelial cells and mediate scavenging and cell adhesive functions.
Biochemical and biophysical research communications 2009;390(3):883-6.
2009: Ruomei Li; Peter A G McCourt; Kai Schledzewski; Sergij Goerdt; Gerhard Moldenhauer; Xipu Liu; Bård Smedsrød; Karen Kristine Sørensen
Endocytosis of advanced glycation end-products in bovine choriocapillaris endothelial cells.
Microcirculation (New York, N.Y. : 1994) 2009;16(7):640-55.
2009: Geir I Nedredal; Kjetil Elvevold; Lars M Ytrebø; Ole-Martin Fuskevåg; Ingvild Pettersen; Peter A G McCourt; Kjell Bertheussen; Bård Smedsrød; Arthur Revhaug
Porcine liver sinusoidal endothelial cells contribute significantly to intrahepatic ammonia metabolism.
Hepatology (Baltimore, Md.) 2009;50(3):900-8.
2009: Bård Smedsrød; david le couteur; Kenichi Ikejima; Hartmut Jaeschke; Norifumi Kawada; Makoto Naito; Percy Knolle; Laura Nagy; Haruki Senoo; Fernando Vidal-Vanaclocha; Noriko Yamaguchi
Hepatic sinusoidal cells in health and disease: update from the 14th International Symposium.
Liver international : official journal of the International Association for the Study of the Liver 2009;29(4):490-501.
2008: Kjetil Elvevold; Jaione Simon-Santamaria; Hege Hasvold; Peter A G McCourt; Bård Smedsrød; Karen Sorensen
Liver sinusoidal endothelial cells depend on mannose receptor-mediated recruitment of lysosomal enzymes for normal degradation capacity.
Hepatology (Baltimore, Md.) 2008;48(6):2007-15.
2008: Sandra Sagmeister; Claudia Drucker; Annemarie Losert; Michael Grusch; Anahita Daryabeigi; Wolfram Parzefall; Natascha Rohr-Udilova; Christoph Bichler; Bård Smedsrød; Daniela Kandioler; Thomas Grünberger; Fritz Wrba; Rolf Schulte-Hermann; Bettina Grasl-Kraupp
HB-EGF is a paracrine growth stimulator for early tumor prestages in inflammation-associated hepatocarcinogenesis.
Journal of hepatology 2008;49(6):955-64.
2008: DAVID LE COUTEUR; Alessandra Warren; Victoria C Cogger; Bård Smedsrød; Karen Sorensen; Rafael de Cabo; Robin Fraser; Robert S McCuskey
Old age and the hepatic sinusoid.
Anatomical record (Hoboken, N.J. : 2007) 2008;291(6):672-83.
2008: Kjetil Elvevold; Bård Smedsrød; Inigo Martinez
The liver sinusoidal endothelial cell: a cell type of controversial and confusing identity.
American journal of physiology. Gastrointestinal and liver physiology 2008;294(2):G391-400.
2008: Cristina Ionica Oie; Randi Olsen; Bård Smedsrød; John-Bjarne Hansen
Liver sinusoidal endothelial cells are the principal site for elimination of unfractionated heparin from the circulation.
American journal of physiology. Gastrointestinal and liver physiology 2008;294(2):G520-8.
2008: Inigo Martinez; Geir I Nedredal; Cristina I Øie; Alessandra Warren; Oddmund Johansen; DAVID LE COUTEUR; Bård Smedsrød
The influence of oxygen tension on the structure and function of isolated liver sinusoidal endothelial cells.
Comparative hepatology 2008;7():4.
2008: Montserrat Martin-Armas; Svetlana N Zykova; Bård Smedsrød
Effects of CpG-oligonucleotides, poly I:C and LPS on Atlantic cod scavenger endothelial cells (SEC).
Developmental and comparative immunology 2008;32(2):100-7.
2007: Montserrat Martin-Armas; Ann-Inger Sommer; Bård Smedsrød
Studies on uptake and intracellular processing of infectious pancreatic necrosis virus by Atlantic cod scavenger endothelial cells.
Journal of fish diseases 2007;30(11):701-10.
2007: Yoshiya Ito; Karen Sorensen; Nancy W Bethea; Dmitri Svistounov; Margaret K McCuskey; Bård Smedsrød; Robert S McCuskey
Age-related changes in the hepatic microcirculation in mice.
Experimental gerontology 2007;42(8):789-97.
2007: Geir I Nedredal; Kjetil Elvevold; Lars M Ytrebø; Ole-Martin Fuskevåg; Ingvild Pettersen; Kjell Bertheussen; Bodil Langbakk; Bård Smedsrød; Arthur Revhaug
Significant contribution of liver nonparenchymal cells to metabolism of ammonia and lactate and cocultivation augments the functions of a bioartificial liver.
American journal of physiology. Gastrointestinal and liver physiology 2007;293(1):G75-83.
2007: Ivana Malovic; Karen Sorensen; Kjetil Elvevold; Geir I Nedredal; Steinar Paulsen; Alexander V Erofeev; Bård Smedsrød; Peter A G McCourt
The mannose receptor on murine liver sinusoidal endothelial cells is the main denatured collagen clearance receptor.
Hepatology (Baltimore, Md.) 2007;45(6):1454-61.
2006: Berit Falkowska-Hansen; Inger Oynebråten; Lars Uhlin-Hansen; Bård Smedsrød
Endocytosis and degradation of serglycin in liver sinusoidal endothelial cells.
Molecular and cellular biochemistry 2006;287(1-2):43-52.
2006: Montserrat Martin-Armas; Jaione Simon-Santamaria; Ingvild Pettersen; Ugo Moens; Bård Smedsrød; Baldur Sveinbjørnsson
Toll-like receptor 9 (TLR9) is present in murine liver sinusoidal endothelial cells (LSECs) and mediates the effect of CpG-oligonucleotides.
Journal of hepatology 2006;44(5):939-46.
2005: Ingvild Pettersen; Wenche H Bakkelund; Bård Smedsrød; Baldur Sveinbjørnsson
Osteoprotegerin is expressed in colon carcinoma cells.
Anticancer research 2005;25(6B):3809-16.
2005: Kjetil Elvevold; Geir I Nedredal; Arthur Revhaug; Kjell Bertheussen; Bård Smedsrød
Long-term preservation of high endocytic activity in primary cultures of pig liver sinusoidal endothelial cells.
European journal of cell biology 2005;84(9):749-64.
2005: Berit Hansen; Paola Longati; Kjetil Elvevold; Geir I Nedredal; Kai Schledzewski; Randi Olsen; Martin Falkowski; Julia Kzhyshkowska; Fredrik Carlsson; Sophie Johansson; Bård Smedsrød; Sergij Goerdt; Sophie Johansson; Peter A G McCourt
Stabilin-1 and stabilin-2 are both directed into the early endocytic pathway in hepatic sinusoidal endothelium via interactions with clathrin/AP-2, independent of ligand binding.
Experimental cell research 2005;303(1):160-73.
2004: Dmitri Svistounov; Bård Smedsrød
Hepatic clearance of advanced glycation end products (AGEs)--myth or truth?
Journal of hepatology 2004;41(6):1038-40.
2003: Petra Holmström; Vijole Dzikaite; Rolf Hultcrantz; ojar melefors; Kristina Eckes; Per Stål; Nils Kinnman; Bård Smedsrød; Mats Gåfvels; Gösta Eggertsen
Structure and liver cell expression pattern of the HFE gene in the rat.
Journal of hepatology 2003;39(3):308-14.
2003: Bård Smedsrød; Staffan Johansson; Sergij Goerdt
Shooting HARE.
Glycobiology 2003;13(5):11G-12G; author reply 12G.
2003: Gunhild Øverland; Sigfried Morath; Arne Yndestad; Thomas Hartung; Christoph Thiemermann; Simon J Foster; Bård Smedsrød; Øystein Mathisen; Pål Aukrust; Ansgar O Aasen; Jacob E Wang
Lipoteichoic acid is a potent inducer of cytokine production in rat and human Kupffer cells in vitro.
Surgical infections 2003;4(2):181-91.
2002: Berit Hansen; Beatriz Arteta; Bård Smedsrød
The physiological scavenger receptor function of hepatic sinusoidal endothelial and Kupffer cells is independent of scavenger receptor class A type I and II.
Molecular and cellular biochemistry 2002;240(1-2):1-8.
2002: Berit Hansen; Dmitri Svistounov; Randi Olsen; R Nagai; Seikoh Horiuchi; Bård Smedsrød
Advanced glycation end products impair the scavenger function of rat hepatic sinusoidal endothelial cells.
Diabetologia 2002;45(10):1379-88.
2002: Tore Seternes; Karen Sorensen; Bård Smedsrød
Scavenger endothelial cells of vertebrates: a nonperipheral leukocyte system for high-capacity elimination of waste macromolecules.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(11):7594-7.
2002: Berit Hansen; Jukka Melkko; Bård Smedsrød
Serum is a rich source of ligands for the scavenger receptor of hepatic sinusoidal endothelial cells.
Molecular and cellular biochemistry 2002;229(1-2):63-72.
2001: Tore Seternes; Roy A Dalmo; J Hoffman; Jarl Bøgwald; Svetlana N Zykova; Bård Smedsrød
Scavenger-receptor-mediated endocytosis of lipopolysaccharide in Atlantic cod (Gadus morhua L.).
The Journal of experimental biology 2001;204(Pt 23):4055-64.
2001: V Langaas; Susan Shahzidi; John Inge Johnsen; Bård Smedsrød; Baldur Sveinbjørnsson
Interferon-gamma modulates TRAIL-mediated apoptosis in human colon carcinoma cells.
Anticancer research 2001;21(6A):3733-8.
2001: Karen Sorensen; Ole-Kristian Tollersrud; Gry Evjen; Bård Smedsrød
Mannose-receptor-mediated clearance of lysosomal alpha-mannosidase in scavenger endothelium of cod endocardium.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2001;129(2-3):615-30.
2001: Tore Seternes; Inger Øynbråten; Karen Sorensen; Bård Smedsrød
Specific endocytosis and catabolism in the scavenger endothelial cells of cod (Gadus morhua L.) generate high-energy metabolites.
The Journal of experimental biology 2001;204(Pt 9):1537-46.
2001: Kanako Wake; Y Kawai; Bård Smedsrød
Re-evaluation of the reticulo-endothelial system.
Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia 2001;106(2 Suppl 1):261-9.
2000: Inger Oynebråten; Berit Hansen; Bård Smedsrød; Lars Uhlin-Hansen
Serglycin secreted by leukocytes is efficiently eliminated from the circulation by sinusoidal scavenger endothelial cells in the liver.
Journal of leukocyte biology 2000;67(2):183-8.
1999: Peter A G McCourt; Bård Smedsrød; Jukka Melkko; Sophie Johansson
Characterization of a hyaluronan receptor on rat sinusoidal liver endothelial cells and its functional relationship to scavenger receptors.
Hepatology (Baltimore, Md.) 1999;30(5):1276-86.
1999: C Rushfeldt; Baldur Sveinbjørnsson; Rolf Seljelid; Bård Smedsrød
Early events of hepatic metastasis formation in mice: role of Kupffer and NK-cells in natural and interferon-gamma-stimulated defense.
The Journal of surgical research 1999;82(2):209-15.
1998: T Hellevik; I Martinez; Randi Olsen; B H Toh; P Webster; Bård Smedsrød
Transport of residual endocytosed products into terminal lysosomes occurs slowly in rat liver endothelial cells.
Hepatology (Baltimore, Md.) 1998;28(5):1378-89.
1998: Karen Sorensen; Jukka Melkko; Bård Smedsrød
Scavenger-receptor-mediated endocytosis in endocardial endothelial cells of Atlantic cod Gadus morhua.
The Journal of experimental biology 1998;201(Pt 11):1707-18.
1998: Baldur Sveinbjørnsson; C Rushfeldt; Rolf Seljelid; Bård Smedsrød
Inhibition of establishment and growth of mouse liver metastases after treatment with interferon gamma and beta-1,3-D-glucan.
Hepatology (Baltimore, Md.) 1998;27(5):1241-8.
1998: Y Kawai; Bård Smedsrød; Kjetil Elvevold; Kanako Wake
Uptake of lithium carmine by sinusoidal endothelial and Kupffer cells of the rat liver: new insights into the classical vital staining and the reticulo-endothelial system.
Cell and tissue research 1998;292(2):395-410.
1997: Baldur Sveinbjørnsson; C Rushfeldt; Randi Olsen; Bård Smedsrød; Rolf Seljelid
Cytotoxic effect of cytokines on murine colon carcinoma cells involves TNF-mediated apoptosis.
Biochemical and biophysical research communications 1997;233(1):270-5.
1997: Bård Smedsrød; Jukka Melkko; N Araki; H Sano; Seikoh Horiuchi
Advanced glycation end products are eliminated by scavenger-receptor-mediated endocytosis in hepatic sinusoidal Kupffer and endothelial cells.
The Biochemical journal 1997;322 ( Pt 2)():567-73.
1996: A Asumendi; A Alvarez; I Martinez; Bård Smedsrød; Fernando Vidal-Vanaclocha
Hepatic sinusoidal endothelium heterogeneity with respect to mannose receptor activity is interleukin-1 dependent.
Hepatology (Baltimore, Md.) 1996;23(6):1521-9.
1996: I Martinez; Baldur Sveinbjørnsson; Bård Smedsrød
Nitric oxide down-regulates endocytosis in rat liver endothelial cells.
Biochemical and biophysical research communications 1996;222(3):688-93.
1996: T Hellevik; A Bondevik; Bård Smedsrød
Intracellular fate of endocytosed collagen in rat liver endothelial cells.
Experimental cell research 1996;223(1):39-49.
1995: I Martinez; Baldur Sveinbjørnsson; Fernando Vidal-Vanaclocha; A Asumendi; Bård Smedsrød
Differential cytokine-mediated modulation of endocytosis in rat liver endothelial cells.
Biochemical and biophysical research communications 1995;212(1):235-41.
1995: Bård Smedsrød
Non-invasive means to study the functional status of sinusoidal liver endothelial cells.
Journal of gastroenterology and hepatology 1995;10 Suppl 1():S81-3.
1995: G Ostgaard; T Hellevik; Rolf K Reed; Bård Smedsrød
Lymphatic transport and organ uptake of gelatin and hyaluronan injected into the rat mesentery.
Acta physiologica Scandinavica 1995;153(1):51-60.
1994: Bård Smedsrød; Pieter De Bleser; Filip Braet; P Lovisetti; Karin Vanderkerken; Eddie Wisse; Albert Geerts
Cell biology of liver endothelial and Kupffer cells.
Gut 1994;35(11):1509-16.
1994: Filip Braet; Ronald de Zanger; T Sasaoki; M Baekeland; P Janssens; Bård Smedsrød; Eddie Wisse
Assessment of a method of isolation, purification, and cultivation of rat liver sinusoidal endothelial cells.
Laboratory investigation; a journal of technical methods and pathology 1994;70(6):944-52.
1994: Z Konopski; Bård Smedsrød; Rolf Seljelid; T Eskeland
A novel immunomodulator soluble aminated beta-1,3-D-glucan: binding characteristics to mouse peritoneal macrophages.
Biochimica et biophysica acta 1994;1221(1):61-5.
1994: Jukka Melkko; T Hellevik; Leila Risteli; Juha Risteli; Bård Smedsrød
Clearance of NH2-terminal propeptides of types I and III procollagen is a physiological function of the scavenger receptor in liver endothelial cells.
The Journal of experimental medicine 1994;179(2):405-12.
1993: Nils-Erik Huseby; Bente Mortensen; Bård Smedsrød
Clearance of circulating gamma-glutamyltransferase by the hepatic galactose receptor. Variability in clearance rate due to carbohydrate heterogeneity of the enzyme.
Biochimica et biophysica acta 1993;1156(3):283-7.
1993: C Rushfeldt; Bård Smedsrød
Distribution of colon cancer cells permanently labeled by lectin-mediated endocytosis of a trap label.
Cancer research 1993;53(3):658-62.
1991: Bård Smedsrød; Rolf Seljelid
Fate of intravenously injected aminated beta(1----3) polyglucose derivatized with 125I-tyraminyl cellobiose.
Immunopharmacology 1991;21(3):149-58.
1990: Bård Smedsrød; Jukka Melkko; L Risteli; Juha Risteli
Circulating C-terminal propeptide of type I procollagen is cleared mainly via the mannose receptor in liver endothelial cells.
The Biochemical journal 1990;271(2):345-50.
1990: Bård Smedsrød; H Pertoft; S Gustafson; T C Laurent
Scavenger functions of the liver endothelial cell.
The Biochemical journal 1990;266(2):313-27.
1990: Bård Smedsrød; M Einarsson
Clearance of tissue plasminogen activator by mannose and galactose receptors in the liver.
Thrombosis and haemostasis 1990;63(1):60-6.
1990: Bård Smedsrød
Receptor-mediated endocytosis of connective tissue macromolecules in liver endothelial cells.
Scandinavian journal of clinical and laboratory investigation. Supplementum 1990;202():148-51.
1989: Bård Smedsrød; M Paulsson; S Johansson
Uptake and degradation in vivo and in vitro of laminin and nidogen by rat liver cells.
The Biochemical journal 1989;261(1):37-42.
1988: L B Dahl; T C Laurent; Bård Smedsrød
Preparation of biologically intact radioiodinated hyaluronan of high specific radioactivity: coupling of 125I-tyramine-cellobiose to amino groups after partial N-deacetylation.
Analytical biochemistry 1988;175(2):397-407.
1988: Bård Smedsrød; M Malmgren; J Ericsson; T C Laurent
Morphological studies on endocytosis of chondroitin sulphate proteoglycan by rat liver endothelial cells.
Cell and tissue research 1988;253(1):39-45.
1988: Bård Smedsrød
Aminoterminal propeptide of type III procollagen is cleared from the circulation by receptor-mediated endocytosis in liver endothelial cells.
Collagen and related research 1988;8(4):375-88.
1988: M Einarsson; Bård Smedsrød; H Pertoft
Uptake and degradation of tissue plasminogen activator in rat liver.
Thrombosis and haemostasis 1988;59(3):474-9.
1988: Bård Smedsrød; M Einarsson; H Pertoft
Tissue plasminogen activator is endocytosed by mannose and galactose receptors of rat liver cells.
Thrombosis and haemostasis 1988;59(3):480-4.
1986: T C Laurent; J R Fraser; H Pertoft; Bård Smedsrød
Binding of hyaluronate and chondroitin sulphate to liver endothelial cells.
The Biochemical journal 1986;234(3):653-8.
1985: Bård Smedsrød; H Pertoft
Preparation of pure hepatocytes and reticuloendothelial cells in high yield from a single rat liver by means of Percoll centrifugation and selective adherence.
Journal of leukocyte biology 1985;38(2):213-30.
1985: Bård Smedsrød; L Kjellén; H Pertoft
Endocytosis and degradation of chondroitin sulphate by liver endothelial cells.
The Biochemical journal 1985;229(1):63-71.
1985: Bård Smedsrød; S Johansson; H Pertoft
Studies in vivo and in vitro on the uptake and degradation of soluble collagen alpha 1(I) chains in rat liver endothelial and Kupffer cells.
The Biochemical journal 1985;228(2):415-24.
1985: Bård Smedsrød; H Pertoft; G Eggertsen; C Sundström
Functional and morphological characterization of cultures of Kupffer cells and liver endothelial cells prepared by means of density separation in Percoll, and selective substrate adherence.
Cell and tissue research 1985;241(3):639-49.
1984: Bård Smedsrød; H Pertoft; S Eriksson; J R Fraser; T C Laurent
Studies in vitro on the uptake and degradation of sodium hyaluronate in rat liver endothelial cells.
The Biochemical journal 1984;223(3):617-26.
1983: S Eriksson; J R Fraser; T C Laurent; H Pertoft; Bård Smedsrød
Endothelial cells are a site of uptake and degradation of hyaluronic acid in the liver.
Experimental cell research 1983;144(1):223-8.