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Annette Smith

Research Profile

Living Beings

Chemicals & Drugs

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Two-Hybrid System Techniques

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Publications

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Jessica E Young; Gwenn A Garden; Refugio A Martinez; Fumiaki Tanaka; C Miguel Sandoval; Annette C Smith; Bryce L Sopher; Amy Lin; Kenneth H Fischbeck; Lisa M Ellerby; Richard S Morrison; J. Paul Taylor; Albert R La Spada
Polyglutamine-expanded androgen receptor truncation fragments activate a Bax-dependent apoptotic cascade mediated by DP5/Hrk.
Patrick Weydt; Victor V Pineda; Anne E Torrence; Randell T Libby; Terrence F Satterfield; Eduardo R Lazarowski; Merle L Gilbert; Gregory J Morton; Theodor K Bammler; Andrew D Strand; Libin Cui; Richard P Beyer; Courtney N Easley; Annette C Smith; Dimitri Krainc; Serge Luquet; Ian R Sweet; Michael W Schwartz; Albert R La Spada
Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration.
Yuxin Fan; Pornprot Limprasert; Ian V J Murray; Annette C Smith; Virginia M-Y Lee; John Q Trojanowski; Bryce L Sopher; Albert R La Spada
Beta-synuclein modulates alpha-synuclein neurotoxicity by reducing alpha-synuclein protein expression.

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All Publications

2009: Jessica E Young; Gwenn A Garden; Refugio A Martinez; Fumiaki Tanaka; C Miguel Sandoval; Annette C Smith; Bryce L Sopher; Amy Lin; Kenneth H Fischbeck; Lisa M Ellerby; Richard S Morrison; J. Paul Taylor; Albert R La Spada
Polyglutamine-expanded androgen receptor truncation fragments activate a Bax-dependent apoptotic cascade mediated by DP5/Hrk.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(7):1987-97.
2006: Patrick Weydt; Victor V Pineda; Anne E Torrence; Randell T Libby; Terrence F Satterfield; Eduardo R Lazarowski; Merle L Gilbert; Gregory J Morton; Theodor K Bammler; Andrew D Strand; Libin Cui; Richard P Beyer; Courtney N Easley; Annette C Smith; Dimitri Krainc; Serge Luquet; Ian R Sweet; Michael W Schwartz; Albert R La Spada
Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration.
Cell metabolism 2006;4(5):349-62.
2006: Yuxin Fan; Pornprot Limprasert; Ian V J Murray; Annette C Smith; Virginia M-Y Lee; John Q Trojanowski; Bryce L Sopher; Albert R La Spada
Beta-synuclein modulates alpha-synuclein neurotoxicity by reducing alpha-synuclein protein expression.
Human molecular genetics 2006;15(20):3002-11.
2006: Lisa Chakrabarti; James T Neal; Michael Miles; Refugio A Martinez; Annette C Smith; Bryce L Sopher; Albert R La Spada
The Purkinje cell degeneration 5J mutation is a single amino acid insertion that destabilizes Nna1 protein.
Mammalian genome : official journal of the International Mammalian Genome Society 2006;17(2):103-10.
2004: Shiming Chen; Guang-Hua Peng; Xuejiao Wang; Annette C Smith; Sara K Grote; Bryce L Sopher; Albert R La Spada
Interference of Crx-dependent transcription by ataxin-7 involves interaction between the glutamine regions and requires the ataxin-7 carboxy-terminal region for nuclear localization.
Human molecular genetics 2004;13(1):53-67.
2002: Gwenn A Garden; Randell T Libby; Ying-Hui Fu; Yoshito Kinoshita; Jing Huang; Daniel E Possin; Annette C Smith; Refugio A Martinez; Gabriel C Fine; Sara K Grote; Carol B Ware; David D Einum; Richard S Morrison; Louis J Ptacek; Bryce L Sopher; Albert R La Spada
Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(12):4897-905.
2001: Albert R La Spada; Ying-Hui Fu; Bryce L Sopher; Randell T Libby; X Wang; L Y Li; David D Einum; Jing Huang; Daniel E Possin; Annette C Smith; Refugio A Martinez; KL Koszdin; piper meigs treuting; Carol B Ware; James B Hurley; Louis J Ptácek; S Chen
Polyglutamine-expanded ataxin-7 antagonizes CRX function and induces cone-rod dystrophy in a mouse model of SCA7.
Neuron 2001;31(6):913-27.
2001: Bryce L Sopher; KL Koszdin; M E McClain; S B Myrick; Refugio A Martinez; Annette C Smith; Albert R La Spada
Genomic organization, chromosome location, and expression analysis of mouse beta-synuclein, a candidate for involvement in neurodegeneration.
Cytogenetics and cell genetics 2001;93(1-2):117-23.
2000: Bryce L Sopher; S B Myrick; J Y Hong; Annette C Smith; Albert R La Spada
In vivo expansion of trinucleotide repeats yields plasmid and YAC constructs for targeting and transgenesis.
Gene 2000;261(2):383-90.