FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Andrew Smith

Research Profile

Living Beings

Chemicals & Drugs

Anatomy

Livers

Disorders

Physiology

Devices

Oligonucleotide Array Sequence Analysis

Procedures

Gene Expression Profiling

Co-author Network

Publications

TOP 3
Andrew G Smith; Emma Lloyd Raven; Tatyana Chernova
The regulatory role of heme in neurons.
Tatyana Chernova; Joern Steinert; Paul Richards; Rajendra Mistry; R A John Challiss; Rebekah Jukes-Jones; Kelvin Cain; Andrew G Smith; Ian D Forsythe
Early failure of N-methyl-D-aspartate receptors and deficient spine formation induced by reduction of regulatory heme in neurons.
Madhuvanthi Kannan; Joern Steinert; Ian D Forsythe; Andrew G Smith; Tatyana Chernova
Mevastatin accelerates loss of synaptic proteins and neurite degeneration in aging cortical neurons in a heme-independent manner.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Andrew Smith (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2011: Andrew G Smith; Emma Lloyd Raven; Tatyana Chernova
The regulatory role of heme in neurons.
Metallomics : integrated biometal science 2011;3(10):955-62.
2011: Tatyana Chernova; Joern Steinert; Paul Richards; Rajendra Mistry; R A John Challiss; Rebekah Jukes-Jones; Kelvin Cain; Andrew G Smith; Ian D Forsythe
Early failure of N-methyl-D-aspartate receptors and deficient spine formation induced by reduction of regulatory heme in neurons.
Molecular pharmacology 2011;79(5):844-54.
2010: Madhuvanthi Kannan; Joern Steinert; Ian D Forsythe; Andrew G Smith; Tatyana Chernova
Mevastatin accelerates loss of synaptic proteins and neurite degeneration in aging cortical neurons in a heme-independent manner.
Neurobiology of aging 2010;31(9):1543-53.
2010: Andrew G Smith; George H Elder
Complex gene-chemical interactions: hepatic uroporphyria as a paradigm.
Chemical research in toxicology 2010;23(4):712-23.
2010: Katie Ridd; Sonia Dhir; Andrew G Smith; Timothy W Gant
Defective TPA signalling compromises HaCat cells as a human in vitro skin carcinogenesis model.
Toxicology in vitro : an international journal published in association with BIBRA 2010;24(3):910-5.
2008: Tatyana Chernova; Fiona M Higginson; Reginald Davies; Andrew G Smith
B2 SINE retrotransposon causes polymorphic expression of mouse 5-aminolevulinic acid synthase 1 gene.
Biochemical and biophysical research communications 2008;377(2):515-20.
2008: Colin D Glen; Andrew G Smith; Yuri E Dubrova
Single-molecule PCR analysis of germ line mutation induction by anticancer drugs in mice.
Cancer research 2008;68(10):3630-6.
2008: Andrew G Smith; Marriane Hansson; Antonio Rodriguez-Pichardo; Ana Ferrer-Dufol; Reinhard T Neubert; Jessie R Webb; Christopher Rappe; Diether Neubert
Polychlorinated dibenzo-p-dioxins and the human immune system: 4 studies on two Spanish families with increased body burdens of highly chlorinated PCDDs.
Environment international 2008;34(3):330-44.
2008: Reginald Davies; Bruce Clothier; Susan W Robinson; Richard E Edwards; Peter Greaves; Jinli Luo; Timothy W Gant; Tatyana Chernova; Andrew G Smith
Essential role of the AH receptor in the dysfunction of heme metabolism induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Chemical research in toxicology 2008;21(2):330-40.
2007: Tatyana Chernova; Joern Steinert; Christopher J Guerin; Pierluigi Nicotera; Ian D Forsythe; Andrew G Smith
Neurite degeneration induced by heme deficiency mediated via inhibition of NMDA receptor-dependent extracellular signal-regulated kinase 1/2 activation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(32):8475-85.
2006: Chang Kee Lim; Malcolm Danton; Bruce Clothier; Andrew G Smith
Dihydroxy-, hydroxyspirolactone-, and dihydroxyspirolactone-urochlorins induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the liver of mice.
Chemical research in toxicology 2006;19(12):1660-7.
2006: Katie Ridd; Shu-Dong Zhang; Richard E Edwards; Reginald Davies; Peter Greaves; Alison Wolfreys; Andrew G Smith; Timothy W Gant
Association of gene expression with sequential proliferation, differentiation and tumor formation in murine skin.
Carcinogenesis 2006;27(8):1556-66.
2006: Gemma R Grant; Susan W Robinson; Richard E Edwards; Bruce Clothier; Reginald Davies; David J Judah; Karl W Broman; Andrew G Smith
Multiple polymorphic loci determine basal hepatic and splenic iron status in mice.
Hepatology (Baltimore, Md.) 2006;44(1):174-85.
2006: Tatyana Chernova; Pierluigi Nicotera; Andrew G Smith
Heme deficiency is associated with senescence and causes suppression of N-methyl-D-aspartate receptor subunits expression in primary cortical neurons.
Molecular pharmacology 2006;69(3):697-705.
2005: Karen L-A Burr; Andrew G Smith; Yuri E Dubrova
p53 deficiency does not affect mutation rate in the mouse germline.
Oncogene 2005;24(26):4315-8.
2005: Peter Greaves; Bruce Clothier; Reginald Davies; Fiona M Higginson; Richard E Edwards; Timothy P Dalton; Daniel W Nebert; Andrew G Smith
Uroporphyria and hepatic carcinogenesis induced by polychlorinated biphenyls-iron interaction: absence in the Cyp1a2(-/-) knockout mouse.
Biochemical and biophysical research communications 2005;331(1):147-52.
2005: Reginald Davies; Arenda Schuurman; Colin R Barker; Bruce Clothier; Tatyana Chernova; Fiona M Higginson; David J Judah; David Dinsdale; Richard E Edwards; Peter Greaves; Timothy W Gant; Andrew G Smith
Hepatic gene expression in protoporphyic Fech mice is associated with cholestatic injury but not a marked depletion of the heme regulatory pool.
The American journal of pathology 2005;166(4):1041-53.
2005: Andrew Green; Jerry A Styles; Emma L Parrott; Douglas Gray; Richard E Edwards; Andrew G Smith; Timothy W Gant; Peter Greaves; Farook Al-Azzawi; Ian N H White
Neonatal tamoxifen treatment of mice leads to adenomyosis but not uterine cancer.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2005;56(4-5):255-63.
2003: Carles vilarino-guell; Andrew G Smith; Yuri E Dubrova
Germline mutation induction at mouse repeat DNA loci by chemical mutagens.
Mutation research 2003;526(1-2):63-73.
2003: Andrew G Smith; Reginald Davies; Timothy P Dalton; Marian L Miller; David J Judah; Joan Riley; Timothy W Gant; Daniel W Nebert
Intrinsic hepatic phenotype associated with the Cyp1a2 gene as shown by cDNA expression microarray analysis of the knockout mouse.
EHP toxicogenomics : journal of the National Institute of Environmental Health Sciences 2003;111(1T):45-51.
2003: Timothy W Gant; Petra R Baus; Bruce Clothier; Joan Riley; Reginald Davies; David J Judah; Richard E Edwards; Elisabeth George; Peter Greaves; Andrew G Smith
Gene expression profiles associated with inflammation, fibrosis, and cholestasis in mouse liver after griseofulvin.
EHP toxicogenomics : journal of the National Institute of Environmental Health Sciences 2003;111(1T):37-43.
2002: Sarah Donald; Richard D Verschoyle; Richard Edwards; David J Judah; Reginald Davies; Joan Riley; David Dinsdale; Luis Lopez-Lazaro; Andrew G Smith; Timothy W Gant; Peter Greaves; Andreas J Gescher
Hepatobiliary damage and changes in hepatic gene expression caused by the antitumor drug ecteinascidin-743 (ET-743) in the female rat.
Cancer research 2002;62(15):4256-62.
2002: Ruth A Akhtar; Akhilesh Reddy; Elizabeth S Maywood; Jonathan D Clayton; Verdun M King; Andrew G Smith; Timothy W Gant; Michael H Hastings; Charalambos P Kyriacou
Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus.
Current biology : CB 2002;12(7):540-50.
2002: Susan W Robinson; Bruce Clothier; Ruth A Akhtar; Ai Li Yang; Isabelle Latour; Carola Van Ijperen; Michael F W Festing; Andrew G Smith
Non-ahr gene susceptibility Loci for porphyria and liver injury induced by the interaction of 'dioxin' with iron overload in mice.
Molecular pharmacology 2002;61(3):674-81.
2001: Andrew G Smith; Bruce Clothier; P Carthew; Nicole L Childs; Peter R Sinclair; Daniel W Nebert; Timothy P Dalton
Protection of the Cyp1a2(-/-) null mouse against uroporphyria and hepatic injury following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Toxicology and applied pharmacology 2001;173(2):89-98.
2001: N J Turton; David J Judah; Joan Riley; Reginald Davies; Doron Lipson; Jerry A Styles; Andrew G Smith; Timothy W Gant
Gene expression and amplification in breast carcinoma cells with intrinsic and acquired doxorubicin resistance.
Oncogene 2001;20(11):1300-6.
2000: Ruth Barber; Mark Plumb; Andrew G Smith; C E Cesar; Emma Boulton; Alec J Jeffreys; Yuri E Dubrova
No correlation between germline mutation at repeat DNA and meiotic crossover in male mice exposed to X-rays or cisplatin.
Mutation research 2000;457(1-2):79-91.
2000: Bruce Clothier; S Robinson; Ruth A Akhtar; J E Francis; T J Peters; K Raja; Andrew G Smith
Genetic variation of basal iron status, ferritin and iron regulatory protein in mice: potential for modulation of oxidative stress.
Biochemical pharmacology 2000;59(2):115-22.
1999: Ai Li Yang; Andrew G Smith; Ruth A Akhtar; Bruce Clothier; S Robinson; M MacFarlane; Michael F W Festing
Low levels of p53 are associated with resistance to tetrachlorodibenzo-p-dioxin toxicity in DBA/2 mice.
Pharmacogenetics 1999;9(2):183-8.
1998: Ruth A Akhtar; Andrew G Smith
Chromosomal linkage analysis of porphyria in mice induced by hexachlorobenzene-iron synergism: a model of sporadic porphyria cutanea tarda.
Pharmacogenetics 1998;8(6):485-94.
1998: Andrew G Smith; Bruce Clothier; S Robinson; M J Scullion; P Carthew; R Edwards; J Luo; Chang Kee Lim; M Toledano
Interaction between iron metabolism and 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice with variants of the Ahr gene: a hepatic oxidative mechanism.
Molecular pharmacology 1998;53(1):52-61.
1997: P Carthew; BM Nolan; Andrew G Smith; Richard E Edwards
Iron promotes DEN initiated GST-P foci in rat liver.
Carcinogenesis 1997;18(3):599-603.
1997: Andrew G Smith; Bruce Clothier; J E Francis; Anthony H Gibbs; Francesco De Matteis; R C Hider
Protoporphyria induced by the orally active iron chelator 1,2-diethyl-3-hydroxypyridin-4-one in C57BL/10ScSn mice.
Blood 1997;89(3):1045-51.
1996: D Constantin; J E Francis; R A Akhtar; Bruce Clothier; Andrew G Smith
Uroporphyria induced by 5-aminolaevulinic acid alone in Ahrd SWR mice.
Biochemical pharmacology 1996;52(9):1407-13.
1996: S Madra; F Mann; J E Francis; Margaret M Manson; Andrew G Smith
Modulation by iron of hepatic microsomal and nuclear cytochrome P450, and cytosolic glutathione S-transferase and peroxidase in C57BL/10ScSn mice induced with polychlorinated biphenyls (Aroclor 1254).
Toxicology and applied pharmacology 1996;136(1):79-86.
1995: Andrew G Smith; P Carthew; Bruce Clothier; D Constantin; J E Francis; S Madra
Synergy of iron in the toxicity and carcinogenicity of polychlorinated biphenyls (PCBs) and related chemicals.
Toxicology letters 1995;82-83():945-50.
1995: Andrew G Smith
Do fruit juices stimulate iron absorption and toxicity?
Human & experimental toxicology 1995;14(10):851-3.
1995: S Madra; Jerry A Styles; Andrew G Smith
Perturbation of hepatocyte nuclear populations induced by iron and polychlorinated biphenyls in C57BL/10ScSn mice during carcinogenesis.
Carcinogenesis 1995;16(4):719-27.
1994: P Carthew; Andrew G Smith
Pathological mechanisms of hepatic tumour formation in rats exposed chronically to dietary hexachlorobenzene.
Journal of applied toxicology : JAT 1994;14(6):447-52.
1994: P Carthew; Andrew G Smith; R C Hider; B Dorman; Richard E Edwards; J E Francis
Potentiation of iron accumulation in cardiac myocytes during the treatment of iron overload in gerbils with the hydroxypyridinone iron chelator CP94.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 1994;7(4):267-71.
1994: Andrew G Smith; P Carthew; J E Francis; K Ingebrigtsen
Influence of iron on the induction of hepatic tumors and porphyria by octachlorostyrene in C57BL/10ScSn mice.
Cancer letters 1994;81(2):145-50.
1993: Andrew G Smith
Toxicology of the lung. An overview of a joint meeting of the British Toxicology Society and the British Association for Lung Research, University of Wales, Cardiff, UK, 24-25 September, 1992.
Human & experimental toxicology 1993;12(5):415-6.
1993: P Carthew; B M Dorman; Richard E Edwards; J E Francis; Andrew G Smith
A unique rodent model for both the cardiotoxic and hepatotoxic effects of prolonged iron overload.
Laboratory investigation; a journal of technical methods and pathology 1993;69(2):217-22.
1991: P Carthew; Richard E Edwards; Andrew G Smith; B Dorman; J E Francis
Rapid induction of hepatic fibrosis in the gerbil after the parenteral administration of iron-dextran complex.
Hepatology (Baltimore, Md.) 1991;13(3):534-9.
1990: P Carthew; Richard E Edwards; Andrew G Smith
Immunotoxic effects of hexachlorobenzene on the pathogenesis of systemic, pneumonic and hepatic virus infections in the mouse.
Human & experimental toxicology 1990;9(6):403-11.