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Bradley Smith

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Chemicals & Drugs

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Publications

TOP 3
Haiying Gan; Allen G Oliver; Bradley D Smith
Fluorine NMR reporter for phosphate anions.
Jung-Jae Lee; Douglas R Rice; Alexander G White; Bradley D Smith
In vivo imaging using polymeric nanoparticles stained with near-infrared chemiluminescent and fluorescent squaraine catenane endoperoxide.
Adam J Plaunt; Meghan B Courbanou; Katrina D Cuison; Kara M Harmatys; Bradley D Smith
Selective non-covalent triggered release from liposomes.

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All Publications

2013: Haiying Gan; Allen G Oliver; Bradley D Smith
Fluorine NMR reporter for phosphate anions.
Chemical communications (Cambridge, England) 2013;49(44):5070-2.
2013: Jung-Jae Lee; Douglas R Rice; Alexander G White; Bradley D Smith
In vivo imaging using polymeric nanoparticles stained with near-infrared chemiluminescent and fluorescent squaraine catenane endoperoxide.
Chemical communications (Cambridge, England) 2013;49(29):3016-8.
2012: Adam J Plaunt; Meghan B Courbanou; Katrina D Cuison; Kara M Harmatys; Bradley D Smith
Selective non-covalent triggered release from liposomes.
Chemical communications (Cambridge, England) 2012;48(65):8123-5.
2012: Erin L Cole; Bryan A Smith; Easwaran Arunkumar; Shuzhang Xiao; Bradley D Smith
Water-soluble, deep-red fluorescent squaraine rotaxanes.
Organic & biomolecular chemistry 2012;10(30):5769-73.
2012: Alexander G White; Brian D Gray; Koon Yan Pak; Bradley D Smith
Deep-red fluorescent imaging probe for bacteria.
Bioorganic & medicinal chemistry letters 2012;22(8):2833-6.
2012: Bryan A Smith; Erin L Cole; James R Johnson; Andrew J Lampkins; Jung-Jae Lee; Edward J O'Neil; Bradley D Smith
Evaluation of fluorescent phosphatidylserine substrates for the aminophospholipid flippase in mammalian cells.
Journal of fluorescence 2012;22(1):93-101.
2011: Carleton G Collins; Jeffrey M Baumes; Bradley D Smith
Thermally-activated chemiluminescent squaraine rotaxane endoperoxide with green emission.
Chemical communications (Cambridge, England) 2011;47(45):12352-4.
2011: Jung-Jae Lee; Allen G Oliver; Jeffrey M Baumes; Richard D Connell; Bradley D Smith
Squaraine [2]catenanes: synthesis, structure and molecular dynamics.
Chemical communications (Cambridge, England) 2011;47(25):7188-90.
2011: Bryan A Smith; Shuzhang Xiao; William R Wolter; James Wheeler; Mark A Suckow; Bradley D Smith
In vivo targeting of cell death using a synthetic fluorescent molecular probe.
Apoptosis : an international journal on programmed cell death 2011;16(7):722-31.
2011: Bryan A Smith; Seth T Gammon; Shuzhang Xiao; Wei Wang; Sarah Chapman; Ryan McDermott; Mark A Suckow; James R Johnson; David Piwnica-Worms; George W Gokel; Bradley D Smith; W Matthew Leevy
In vivo optical imaging of acute cell death using a near-infrared fluorescent zinc-dipicolylamine probe.
Molecular pharmaceutics 2011;8(2):583-90.
2011: Ivan Murgu; Jeffrey M Baumes; Jens Eberhard; Jeremiah J Gassensmith; Easwaran Arunkumar; Bradley D Smith
Macrocycle breathing in [2]rotaxanes with tetralactam macrocycles.
The Journal of organic chemistry 2011;76(2):688-91.
2010: Alexander G White; Na Fu; W Matthew Leevy; Jung-Jae Lee; Michael A Blasco; Bradley D Smith
Optical imaging of bacterial infection in living mice using deep-red fluorescent squaraine rotaxane probes.
Bioconjugate chemistry 2010;21(7):1297-304.
2010: Jeremiah J Gassensmith; Sarah Matthys; Jung-Jae Lee; Aleksandra Wojcik; Prashant V Kamat; Bradley D Smith
Squaraine rotaxane as a reversible optical chloride sensor.
Chemistry (Weinheim an der Bergstrasse, Germany) 2010;16(9):2916-21.
2010: Jung-Jae Lee; Alexander G White; Jeffrey M Baumes; Bradley D Smith
Microwave-assisted slipping synthesis of fluorescent squaraine rotaxane probe for bacterial imaging.
Chemical communications (Cambridge, England) 2010;46(7):1068-9.
2010: Bryan A Smith; Akers Walter; W Matthew Leevy; Andrew J Lampkins; Shuzhang Xiao; William Wolter; Mark A Suckow; Samuel achilefu; Bradley D Smith
Optical imaging of mammary and prostate tumors in living animals using a synthetic near infrared zinc(II)-dipicolylamine probe for anionic cell surfaces.
Journal of the American Chemical Society 2010;132(1):67-9.
2010: Shuzhang Xiao; Na Fu; Kaitlin Peckham; Bradley D Smith
Efficient synthesis of fluorescent squaraine rotaxane dendrimers.
Organic letters 2010;12(1):140-3.
2009: Jeremiah J Gassensmith; Jeffrey M Baumes; Bradley D Smith
Discovery and early development of squaraine rotaxanes.
Chemical communications (Cambridge, England) 2009;(42):6329-38.
2009: Na Fu; Jeffrey M Baumes; Easwaran Arunkumar; Bruce C Noll; Bradley D Smith
Squaraine rotaxanes with boat conformation macrocycles.
The Journal of organic chemistry 2009;74(17):6462-8.
2009: Jeremiah J Gassensmith; Jeffrey M Baumes; Jens Eberhard; Bradley D Smith
Cycloaddition to an anthracene-derived macrocyclic receptor with supramolecular control of regioselectivity.
Chemical communications (Cambridge, England) 2009;(18):2517-9.
2009: Jung-Jae Lee; Bradley D Smith
Fluorescent chemosensor for reactive organohalides in micellar solution with an example of autocatalysis.
Chemical communications (Cambridge, England) 2009;(15):1962-3.
2008: Beth A McNally; Edward J O'Neil; Anh Nguyen; Bradley D Smith
Membrane transporters for anions that use a relay mechanism.
Journal of the American Chemical Society 2008;130(51):17274-5.
2008: Andrew J Lampkins; Edward J O'Neil; Bradley D Smith
Bio-orthogonal phosphatidylserine conjugates for delivery and imaging applications.
The Journal of organic chemistry 2008;73(16):6053-8.
2008: W Matthew Leevy; Timothy N Lambert; James R Johnson; Joshua Morris; Bradley D Smith
Quantum dot probes for bacteria distinguish Escherichia coli mutants and permit in vivo imaging.
Chemical communications (Cambridge, England) 2008;(20):2331-3.
2008: James R Johnson; Hua Jiang; Bradley D Smith
Zinc(II)-coordinated oligotyrosine: a new class of cell penetrating peptide.
Bioconjugate chemistry 2008;19(5):1033-9.
2008: Jung-Jae Lee; Bruce C Noll; Bradley D Smith
Fluorescent chemosensor for chloroalkanes.
Organic letters 2008;10(9):1735-8.
2008: W Matthew Leevy; Seth T Gammon; James R Johnson; Andrew J Lampkins; Hua Jiang; Manuel Marquez; David Piwnica-Worms; Mark A Suckow; Bradley D Smith
Noninvasive optical imaging of staphylococcus aureus bacterial infection in living mice using a Bis-dipicolylamine-Zinc(II) affinity group conjugated to a near-infrared fluorophore.
Bioconjugate chemistry 2008;19(3):686-92.
2008: Kristy M DiVittorio; W Matthew Leevy; Edward J O'Neil; James R Johnson; Sergei B Vakulenko; Joshua D Morris; Kristine D Rosek; Nathan Serazin; Sarah Hilkert; Scott Hurley; Manuel Marquez; Bradley D Smith
Zinc(II) coordination complexes as membrane-active fluorescent probes and antibiotics.
Chembiochem : a European journal of chemical biology 2008;9(2):286-93.
2008: Beth A McNally; Atanas Koulov; Timothy N Lambert; Bradley D Smith; Jean-Baptiste Joos; Adam L Sisson; John P Clare; Valentina Sgarlata; Luke W Judd; Germinal Magro; Anthony P Davis
Structure-activity relationships in cholapod anion carriers: enhanced transmembrane chloride transport through substituent tuning.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(31):9599-606.
2008: Roger G Hanshaw; Robert V Stahelin; Bradley D Smith
Noncovalent keystone interactions controlling biomembrane structure.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(6):1690-7.
2007: Keith J Stanger; Jung-Jae Lee; Bradley D Smith
Dramatic acceleration of the Menschutkin reaction and distortion of halide leaving-group order.
The Journal of organic chemistry 2007;72(25):9663-8.
2007: Jeremiah Gassensmith; Easwaran Arunkumar; Lorna Barr; Jeffrey M Baumes; Kristy M DiVittorio; James R Johnson; Bruce C Noll; Bradley D Smith
Self-assembly of fluorescent inclusion complexes in competitive media including the interior of living cells.
Journal of the American Chemical Society 2007;129(48):15054-9.
2007: Anthony P Davis; David N Sheppard; Bradley D Smith
Development of synthetic membrane transporters for anions.
Chemical Society reviews 2007;36(2):348-57.
2007: Edward J O'Neil; Kristy M DiVittorio; Bradley D Smith
Phosphatidylcholine-derived bolaamphiphiles via click chemistry.
Organic letters 2007;9(2):199-202.
2007: James R Johnson; Na Fu; Easwaran Arunkumar; W Matthew Leevy; Seth T Gammon; David Piwnica-Worms; Bradley D Smith
Squaraine rotaxanes: superior substitutes for Cy-5 in molecular probes for near-infrared fluorescence cell imaging.
Angewandte Chemie (International ed. in English) 2007;46(29):5528-31.
2006: W Matthew Leevy; Seth T Gammon; Hua Jiang; James R Johnson; Dustin J Maxwell; Erin N Jackson; Manuel Marquez; David Piwnica-Worms; Bradley D Smith
Optical imaging of bacterial infection in living mice using a fluorescent near-infrared molecular probe.
Journal of the American Chemical Society 2006;128(51):16476-7.
2006: Christopher C Forbes; Kristy M DiVittorio; Bradley D Smith
Bolaamphiphiles promote phospholipid translocation across vesicle membranes.
Journal of the American Chemical Society 2006;128(28):9211-8.
2006: Easwaran Arunkumar; Na Fu; Bradley D Smith
Squaraine-derived rotaxanes: highly stable, fluorescent near-IR dyes.
Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(17):4684-90.
2006: Kristy M DiVittorio; James R Johnson; Emma Johansson; Aaron J Reynolds; Katrina A Jolliffe; Bradley D Smith
Synthetic peptides with selective affinity for apoptotic cells.
Organic & biomolecular chemistry 2006;4(10):1966-76.
2006: W Matthew Leevy; James R Johnson; C Lakshmi; Joshua Morris; Manuel Marquez; Bradley D Smith
Selective recognition of bacterial membranes by zinc(II)-coordination complexes.
Chemical communications (Cambridge, England) 2006;(15):1595-7.
2006: Hua Jiang; Bradley D Smith
Dynamic molecular recognition on the surface of vesicle membranes.
Chemical communications (Cambridge, England) 2006;(13):1407-9.
2005: Roger G Hanshaw; C Lakshmi; Timothy N Lambert; James R Johnson; Bradley D Smith
Fluorescent detection of apoptotic cells by using zinc coordination complexes with a selective affinity for membrane surfaces enriched with phosphatidylserine.
Chembiochem : a European journal of chemical biology 2005;6(12):2214-20.
2005: Roger G Hanshaw; Bradley D Smith
New reagents for phosphatidylserine recognition and detection of apoptosis.
Bioorganic & medicinal chemistry 2005;13(17):5035-42.
2005: John P Clare; Alan J Ayling; Jean-Baptiste Joos; Adam L Sisson; Germinal Magro; M Nieves Pérez-Payán; Timothy N Lambert; Rameshwer Shukla; Bradley D Smith; Anthony P Davis
Substrate discrimination by cholapod anion receptors: geometric effects and the "affinity-selectivity principle".
Journal of the American Chemical Society 2005;127(30):10739-46.
2005: Kristy M DiVittorio; Timothy N Lambert; Bradley D Smith
Steroid-derived phospholipid scramblases induce exposure of phosphatidylserine on the surface of red blood cells.
Bioorganic & medicinal chemistry 2005;13(14):4485-90.
2005: Hua Jiang; Edward J O'neil; Kristy M DiVittorio; Bradley D Smith
Anion-mediated phase transfer of Zinc(II)-coordinated tyrosine derivatives.
Organic letters 2005;7(14):3013-6.
2005: Jung-Jae Lee; Keith J Stanger; Bruce C Noll; Carlos Gonzalez; Manuel Marquez; Bradley D Smith
Rapid fixation of methylene chloride by a macrocyclic amine.
Journal of the American Chemical Society 2005;127(12):4184-5.
2005: Easwaran Arunkumar; Christopher C Forbes; Bruce C Noll; Bradley D Smith
Squaraine-derived rotaxanes: sterically protected fluorescent near-IR dyes.
Journal of the American Chemical Society 2005;127(10):3288-9.
2005: Joseph M Mahoney; Kenneth A Stucker; Hua Jiang; Ian Carmichael; Nicole R Brinkmann; Alicia M Beatty; Bruce C Noll; Bradley D Smith
Molecular recognition of trigonal oxyanions using a ditopic salt receptor: evidence for anisotropic shielding surface around nitrate anion.
Journal of the American Chemical Society 2005;127(9):2922-8.
2005: Beth A McNally; Atanas Koulov; Bradley D Smith; Jean-Baptiste Joos; Anthony P Davis
A fluorescent assay for chloride transport; identification of a synthetic anionophore with improved activity.
Chemical communications (Cambridge, England) 2005;(8):1087-9.
2004: Joseph M Mahoney; Alicia M Beatty; Bradley D Smith
Selective solid-liquid extraction of lithium halide salts using a ditopic macrobicyclic receptor.
Inorganic chemistry 2004;43(24):7617-21.
2004: Joseph M Mahoney; Gayathri U Nawaratna; Alicia M Beatty; Peter J Duggan; Bradley D Smith
Transport of alkali halides through a liquid organic membrane containing a ditopic salt-binding receptor.
Inorganic chemistry 2004;43(19):5902-7.
2004: Rameshwer Shukla; Yoshihiro Sasaki; Viktor Krchnák; Bradley D Smith
Identification of synthetic phosphatidylserine translocases from a combinatorial library prepared by directed split-and-pool synthesis.
Journal of combinatorial chemistry 2004;6(5):703-9.
2004: Yoshihiro Sasaki; Rameshwer Shukla; Bradley D Smith
Facilitated phosphatidylserine flip-flop across vesicle and cell membranes using urea-derived synthetic translocases.
Organic & biomolecular chemistry 2004;2(2):214-9.
2003: Lauri Vares; Atanas Koulov; Bradley D Smith
Synthesis and supramolecular properties of conformationally restricted and flexible phospholipids.
The Journal of organic chemistry 2003;68(26):10073-8.
2003: Joseph M Mahoney; John P Davis; Alicia M Beatty; Bradley D Smith
Molecular recognition of alkylammonium contact ion-pairs using a ditopic receptor.
The Journal of organic chemistry 2003;68(25):9819-20.
2003: Atanas Koulov; Timothy N Lambert; Rameshwer Shukla; Mahim Jain; J Middleton Boon; Bradley D Smith; Hongyu Li; David N Sheppard; Jean-Baptiste Joos; John P Clare; Anthony P Davis
Chloride transport across vesicle and cell membranes by steroid-based receptors.
Angewandte Chemie (International ed. in English) 2003;42(40):4931-3.
2003: Bradley D Smith; Timothy N Lambert
Molecular ferries: membrane carriers that promote phospholipid flip-flop and chloride transport.
Chemical communications (Cambridge, England) 2003;(18):2261-8.
2003: J Middleton Boon; Timothy N Lambert; Adam L Sisson; Anthony P Davis; Bradley D Smith
Facilitated phosphatidylserine (PS) flip-flop and thrombin activation using a synthetic PS scramblase.
Journal of the American Chemical Society 2003;125(27):8195-201.
2003: Atanas Koulov; Joseph M Mahoney; Bradley D Smith
Facilitated transport of sodium or potassium chloride across vesicle membranes using a ditopic salt-binding macrobicycle.
Organic & biomolecular chemistry 2003;1(1):27-9.
2002: J Middleton Boon; Bradley D Smith
Synthetic membrane transporters.
Current opinion in chemical biology 2002;6(6):749-56.
2002: Atanas Koulov; Lauri Vares; Mahim Jain; Bradley D Smith
Cationic triple-chain amphiphiles facilitate vesicle fusion compared to double-chain or single-chain analogues.
Biochimica et biophysica acta 2002;1564(2):459-65.
2002: Yvonne R Vandenburg; Bradley D Smith; Eric Biron; Normand Voyer
Membrane disruption ability of facially amphiphilic helical peptides.
Chemical communications (Cambridge, England) 2002;(16):1694-5.
2002: Lauri Vares; Atanas Koulov; Bradley D Smith
Highly impermeable vesicles composed of conformationally restricted phosphatidylethanolamine.
Chemical communications (Cambridge, England) 2002;(14):1482-3.
2002: Martin J Deetz; Christopher C Forbes; Marco Jonas; Jeremiah P Malerich; Bradley D Smith; Olaf Wiest
Unusually low barrier to carbamate C-N rotation.
The Journal of organic chemistry 2002;67(11):3949-52.
2002: Timothy N Lambert; J Middleton Boon; Bradley D Smith; M Nieves Pérez-Payán; Anthony P Davis
Facilitated phospholipid flip-flop using synthetic steroid-derived translocases.
Journal of the American Chemical Society 2002;124(19):5276-7.
2002: J Middleton Boon; Bradley D Smith
Chemical control of phospholipid distribution across bilayer membranes.
Medicinal research reviews 2002;22(3):251-81.
2002: J Middleton Boon; Timothy N Lambert; Bradley D Smith; Alicia M Beatty; Vesela Ugrinova; Seth N Brown
Structure/activity study of tris(2-aminoethyl)amine-derived translocases for phosphatidylcholine.
The Journal of organic chemistry 2002;67(7):2168-74.
2002: Joseph M Mahoney; Rameshwer Shukla; R Andrew Marshall; Alicia M Beatty; Jaroslav Zajicek; Bradley D Smith
Templated conversion of a crown ether-containing macrobicycle into [2]rotaxanes.
The Journal of organic chemistry 2002;67(5):1436-40.
2002: J Middleton Boon; Rameshwer Shukla; Bradley D Smith; Giulia Licini; Paolo Scrimin
Selective phosphatidylethanolamine translocation across vesicle membranes using synthetic translocases.
Chemical communications (Cambridge, England) 2002;(3):260-1.
2001: C C Forbes; Alicia M Beatty; Bradley D Smith
Using pentafluorophenyl as a Lewis acid to stabilize a cis secondary amide conformation.
Organic letters 2001;3(22):3595-8.
2001: J Middleton Boon; Bradley D Smith
Facilitated phosphatidylcholine flip-flop across erythrocyte membranes using low molecular weight synthetic translocases.
Journal of the American Chemical Society 2001;123(26):6221-6.
2001: Joseph M Mahoney; Alicia M Beatty; Bradley D Smith
Selective recognition of an alkali halide contact ion-pair.
Journal of the American Chemical Society 2001;123(24):5847-8.
2000: Z Y Zhang; Bradley D Smith
High-generation polycationic dendrimers are unusually effective at disrupting anionic vesicles: membrane bending model.
Bioconjugate chemistry 2000;11(6):805-14.
1999: Z Y Zhang; Bradley D Smith
Synthesis and characterization of NVOC-DOPE, a caged photoactivatable derivative of dioleoylphosphatidylethanolamine.
Bioconjugate chemistry 1999;10(6):1150-2.