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David Smith

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Procedures

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequence

Physiology

Protein Folding

Anatomy

Crystalline Lens

Concepts & Ideas

Disorders

Protein Denaturation

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Network (preview)

Co-Publications
Name
25
Smith, Jean
10
Lapko, Veniamin
5
Wang, Lintao
4
Ma, Z
4
Chen, J
4
David, Larry
4
Deng, Y
4
Hanson, Stephen
3
Jiang, XY
3
Lampi, Kirsten
3
Engen, John
3
Smithgall, Thomas
3
Song, Pill-Soon
3
Pan, Hai
3
Gmeiner, William

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Publications

TOP 3
Wang Lintao; Smith David L
Capsid structure and dynamics of a human rhinovirus probed by hydrogen exchange mass spectrometry.
Wintrode Patrick L; Rojsajjakul Teerapat; Vadrevu Ramakrishna; Matthews C Robert; Smith David L
An obligatory intermediate controls the folding of the alpha-subunit of tryptophan synthase, a TIM barrel protein.
Lapko Veniamin N; Cerny Ronald L; Smith David L; Smith Jean B
Modifications of human betaA1/betaA3-crystallins include S-methylation, glutathiolation, and truncation.

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All Publications

2005: Wang Lintao; Smith David L
Capsid structure and dynamics of a human rhinovirus probed by hydrogen exchange mass spectrometry.
Protein science : a publication of the Protein Society 2005;14(6):1661-72.
2005: Wintrode Patrick L; Rojsajjakul Teerapat; Vadrevu Ramakrishna; Matthews C Robert; Smith David L
An obligatory intermediate controls the folding of the alpha-subunit of tryptophan synthase, a TIM barrel protein.
Journal of molecular biology 2005;347(5):911-9.
2005: Lapko Veniamin N; Cerny Ronald L; Smith David L; Smith Jean B
Modifications of human betaA1/betaA3-crystallins include S-methylation, glutathiolation, and truncation.
Protein science : a publication of the Protein Society 2005;14(1):45-54.
2004: Swaim Catherine L; Smith David L; Smith Jean B
The reaction of alpha-crystallin with the cross-linker 3,3'-dithiobis(sulfosuccinimidyl propionate) demonstrates close proximity of the C termini of alphaA and alphaB in the native assembly.
Protein science : a publication of the Protein Society 2004;13(10):2832-5.
2004: Rojsajjakul Teerapat; Wintrode Patrick; Vadrevu Ramakrishna; Robert Matthews C; Smith David L
Multi-state unfolding of the alpha subunit of tryptophan synthase, a TIM barrel protein: insights into the secondary structure of the stable equilibrium intermediates by hydrogen exchange mass spectrometry.
Journal of molecular biology 2004;341(1):241-53.
2004: Swaim Catherine L; Smith Jean B; Smith David L
Unexpected products from the reaction of the synthetic cross-linker 3,3'-dithiobis(sulfosuccinimidyl propionate), DTSSP with peptides.
Journal of the American Society for Mass Spectrometry 2004;15(5):736-49.
2004: Pan Hai; Raza Ashraf S; Smith David L
Equilibrium and kinetic folding of rabbit muscle triosephosphate isomerase by hydrogen exchange mass spectrometry.
Journal of molecular biology 2004;336(5):1251-63.
2004: Hasan Azeem; Yu Jiong; Smith David L; Smith Jean B
Thermal stability of human alpha-crystallins sensed by amide hydrogen exchange.
Protein science : a publication of the Protein Society 2004;13(2):332-41.
2004: Raza A S; Smith D L
Optimization of conditions for studies of protein unfolding by hydrogen exchange/mass spectrometry.
European journal of mass spectrometry (Chichester, England) 2004;10(2):289-94.
2003: Wintrode Patrick L; Friedrich Kenneth L; Vierling Elizabeth; Smith Jean B; Smith David L
Solution structure and dynamics of a heat shock protein assembly probed by hydrogen exchange and mass spectrometry.
Biochemistry 2003;42(36):10667-73.
2003: Lapko Veniamin N; Smith David L; Smith Jean B
Expression of betaA2-crystallin in human lenses.
Experimental eye research 2003;77(3):383-5.
2003: Zhang Zhongli; Smith David L; Smith Jean B
Human beta-crystallins modified by backbone cleavage, deamidation and oxidation are prone to associate.
Experimental eye research 2003;77(3):259-72.
2003: Lapko Veniamin N; Smith David L; Smith Jean B
Methylation and carbamylation of human gamma-crystallins.
Protein science : a publication of the Protein Society 2003;12(8):1762-74.
2003: Pan Hai; Smith David L
Quaternary structure of aldolase leads to differences in its folding and unfolding intermediates.
Biochemistry 2003;42(19):5713-21.
2003: Wang Lintao; Smith David L
Downsizing improves sensitivity 100-fold for hydrogen exchange-mass spectrometry.
Analytical biochemistry 2003;314(1):46-53.
2002: Hasan Azeem; Smith David L; Smith Jean B
Alpha-crystallin regions affected by adenosine 5'-triphosphate identified by hydrogen-deuterium exchange.
Biochemistry 2002;41(52):15876-82.
2002: Lapko Veniamin N; Smith David L; Smith Jean B
S-methylated cysteines in human lens gamma S-crystallins.
Biochemistry 2002;41(50):14645-51.
2002: Wang Lintao; Smith David L
Probing protein structure and dynamics by hydrogen exchange-mass spectrometry.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2002;Chapter 17():Unit 17.6.
2002: Lapko Veniamin N; Purkiss Andrew G; Smith David L; Smith Jean B
Deamidation in human gamma S-crystallin from cataractous lenses is influenced by surface exposure.
Biochemistry 2002;41(27):8638-48.
2002: Wang Lintao; Pan Hai; Smith David L
Hydrogen exchange-mass spectrometry: optimization of digestion conditions.
Molecular & cellular proteomics : MCP 2002;1(2):132-8.
2001: Zhang Z; Smith D L; Smith J B
Multiple separations facilitate identification of protein variants by mass spectrometry.
Proteomics 2001;1(8):1001-9.
2001: Chen J; Walter S; Horwich A L; Smith D L
Folding of malate dehydrogenase inside the GroEL-GroES cavity.
Nature structural biology 2001;8(8):721-8.
2001: Zhang Z; David L L; Smith D L; Smith J B
Resistance of human betaB2-crystallin to in vivo modification.
Experimental eye research 2001;73(2):203-11.
2001: Wang L; Lane L C; Smith D L
Detecting structural changes in viral capsids by hydrogen exchange and mass spectrometry.
Protein science : a publication of the Protein Society 2001;10(6):1234-43.
2001: Lapko V N; Smith D L; Smith J B
In vivo carbamylation and acetylation of water-soluble human lens alphaB-crystallin lysine 92.
Protein science : a publication of the Protein Society 2001;10(6):1130-6.
2001: Chen J; Smith D L
Amide hydrogen exchange shows that malate dehydrogenase is a folded monomer at pH 5.
Protein science : a publication of the Protein Society 2001;10(5):1079-83.
2000: Hanson S R; Hasan A; Smith D L; Smith J B
The major in vivo modifications of the human water-insoluble lens crystallins are disulfide bonds, deamidation, methionine oxidation and backbone cleavage.
Experimental eye research 2000;71(2):195-207.
2000: Raza A S; Dharmasiri K; Smith D L
Identification of non-covalent structure in apocytochrome c by hydrogen exchange and mass spectrometry.
Journal of mass spectrometry : JMS 2000;35(5):612-7.
2000: Lapko V N; Smith D L; Smith J B
Identification of an artifact in the mass spectrometry of proteins derivatized with iodoacetamide.
Journal of mass spectrometry : JMS 2000;35(4):572-5.
2000: Feng J; Smith D L; Smith J B
Human lens beta-crystallin solubility.
The Journal of biological chemistry 2000;275(16):11585-90.
2000: Chen J; Smith D L
Unfolding and disassembly of the chaperonin GroEL occurs via a tetradecameric intermediate with a folded equatorial domain.
Biochemistry 2000;39(15):4250-8.
1999: Deng Y; Smith D L
Rate and equilibrium constants for protein unfolding and refolding determined by hydrogen exchange-mass spectrometry.
Analytical biochemistry 1999;276(2):150-60.
1999: Deng Y; Smith D L
Hydrogen exchange demonstrates three domains in aldolase unfold sequentially.
Journal of molecular biology 1999;294(1):247-58.
1999: Deng Y; Zhang Z; Smith D L
Comparison of continuous and pulsed labeling amide hydrogen exchange/mass spectrometry for studies of protein dynamics.
Journal of the American Society for Mass Spectrometry 1999;10(8):675-84.
1999: Engen J R; Gmeiner W H; Smithgall T E; Smith D L
Hydrogen exchange shows peptide binding stabilizes motions in Hck SH2.
Biochemistry 1999;38(28):8926-35.
1999: Lapko V N; Jiang X Y; Smith D L; Song P S
Mass spectrometric characterization of oat phytochrome A: isoforms and posttranslational modifications.
Protein science : a publication of the Protein Society 1999;8(5):1032-44.
1999: Engen J R; Smithgall T E; Gmeiner W H; Smith D L
Comparison of SH3 and SH2 domain dynamics when expressed alone or in an SH(3+2) construct: the role of protein dynamics in functional regulation.
Journal of molecular biology 1999;287(3):645-56.
1998: Hanson S R; Smith D L; Smith J B
Deamidation and disulfide bonding in human lens gamma-crystallins.
Experimental eye research 1998;67(3):301-12.
1998: Lapko V N; Jiang X Y; Smith D L; Song P S
Surface topography of phytochrome A deduced from specific chemical modification with iodoacetamide.
Biochemistry 1998;37(36):12526-35.
1998: Chen J; Smith D L; Griep M A
The role of the 6 lysines and the terminal amine of Escherichia coli single-strand binding protein in its binding of single-stranded DNA.
Protein science : a publication of the Protein Society 1998;7(8):1781-8.
1998: Lampi K J; Ma Z; Hanson S R; Azuma M; Shih M; Shearer T R; Smith D L; Smith J B; David L L
Age-related changes in human lens crystallins identified by two-dimensional electrophoresis and mass spectrometry.
Experimental eye research 1998;67(1):31-43.
1998: Ma Z; Hanson S R; Lampi K J; David L L; Smith D L; Smith J B
Age-related changes in human lens crystallins identified by HPLC and mass spectrometry.
Experimental eye research 1998;67(1):21-30.
1998: Lin P P; Barry R C; Smith D L; Smith J B
In vivo acetylation identified at lysine 70 of human lens alphaA-crystallin.
Protein science : a publication of the Protein Society 1998;7(6):1451-7.
1998: Deng Y; Smith D L
Identification of unfolding domains in large proteins by their unfolding rates.
Biochemistry 1998;37(18):6256-62.
1998: Smith D L
Local structure and dynamics in proteins characterized by hydrogen exchange and mass spectrometry.
Biochemistry. Biokhimii?a 1998;63(3):285-93.
1997: Yang H; Smith D L
Kinetics of cytochrome c folding examined by hydrogen exchange and mass spectrometry.
Biochemistry 1997;36(48):14992-9.
1997: Engen J R; Smithgall T E; Gmeiner W H; Smith D L
Identification and localization of slow, natural, cooperative unfolding in the hematopoietic cell kinase SH3 domain by amide hydrogen exchange and mass spectrometry.
Biochemistry 1997;36(47):14384-91.
1997: Lin P; Smith D L; Smith J B
In vivo modification of the C-terminal lysine of human lens alphaB-crystallin.
Experimental eye research 1997;65(5):673-80.
1997: Lapko V N; Jiang X Y; Smith D L; Song P S
Posttranslational modification of oat phytochrome A: phosphorylation of a specific serine in a multiple serine cluster.
Biochemistry 1997;36(34):10595-9.
1997: Ajaz M S; Ma Z; Smith D L; Smith J B
Size of human lens beta-crystallin aggregates are distinguished by N-terminal truncation of betaB1.
The Journal of biological chemistry 1997;272(17):11250-5.
1997: Smith D L; Deng Y; Zhang Z
Probing the non-covalent structure of proteins by amide hydrogen exchange and mass spectrometry.
Journal of mass spectrometry : JMS 1997;32(2):135-46.
1997: Lampi K J; Ma Z; Shih M; Shearer T R; Smith J B; Smith D L; David L L
Sequence analysis of betaA3, betaB3, and betaA4 crystallins completes the identification of the major proteins in young human lens.
The Journal of biological chemistry 1997;272(4):2268-75.
1996: Lund A L; Smith J B; Smith D L
Modifications of the water-insoluble human lens alpha-crystallins.
Experimental eye research 1996;63(6):661-72.
1996: Zhang Z; Smith D L
Thermal-induced unfolding domains in aldolase identified by amide hydrogen exchange and mass spectrometry.
Protein science : a publication of the Protein Society 1996;5(7):1282-9.
1996: Zhang Z; Post C B; Smith D L
Amide hydrogen exchange determined by mass spectrometry: application to rabbit muscle aldolase.
Biochemistry 1996;35(3):779-91.

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