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David Smith

Research Profile

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Kevin J Barnham; Vijaya Kenche; Giuseppe D Ciccotosto; David P Smith; Deborah J Tew; Xiang Liu; Keyla Perez; Greg A Cranston; Timothy J Johanssen; Irene Volitakis; Ashley I Bush; Colin L Masters; Anthony R White; Jeffrey P Smith; Robert A Cherny; Roberto Cappai
Platinum-based inhibitors of amyloid-beta as therapeutic agents for Alzheimer's disease.
Deborah J Tew; Stephen P Bottomley; David P Smith; Giuseppe D Ciccotosto; jeffrey babon; Mark G Hinds; Colin L Masters; Roberto Cappai; Kevin J Barnham
Stabilization of neurotoxic soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptide.
David P Smith; Deborah J Tew; Andrew Hill; Stephen P Bottomley; Colin L Masters; Kevin J Barnham; Roberto Cappai
Formation of a high affinity lipid-binding intermediate during the early aggregation phase of alpha-synuclein.

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All Publications

2008: Kevin J Barnham; Vijaya Kenche; Giuseppe D Ciccotosto; David P Smith; Deborah J Tew; Xiang Liu; Keyla Perez; Greg A Cranston; Timothy J Johanssen; Irene Volitakis; Ashley I Bush; Colin L Masters; Anthony R White; Jeffrey P Smith; Robert A Cherny; Roberto Cappai
Platinum-based inhibitors of amyloid-beta as therapeutic agents for Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(19):6813-8.
2008: Deborah J Tew; Stephen P Bottomley; David P Smith; Giuseppe D Ciccotosto; jeffrey babon; Mark G Hinds; Colin L Masters; Roberto Cappai; Kevin J Barnham
Stabilization of neurotoxic soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptide.
Biophysical journal 2008;94(7):2752-66.
2008: David P Smith; Deborah J Tew; Andrew Hill; Stephen P Bottomley; Colin L Masters; Kevin J Barnham; Roberto Cappai
Formation of a high affinity lipid-binding intermediate during the early aggregation phase of alpha-synuclein.
Biochemistry 2008;47(5):1425-34.
2008: Eleni Giannakis; Lin-Wai Hung; Keyla Perez Camacaro; David P Smith; Kevin J Barnham; John D Wade
Analysis of Abeta interactions using ProteinChip technology.
Methods in molecular biology (Clifton, N.J.) 2008;494():71-86.
2007: Michelle T Fodero-Tavoletti; David P Smith; Catriona A McLean; Paul A Adlard; Kevin J Barnham; Lisa E Foster; Laura Leone; Keyla Perez; Mikhalina Cortés; Janetta G Culvenor; Qiao-Xin Li; Katrina M Laughton; Christopher C Rowe; Colin L Masters; Roberto Cappai; Victor L Villemagne
In vitro characterization of Pittsburgh compound-B binding to Lewy bodies.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(39):10365-71.
2007: David P Smith; Giuseppe D Ciccotosto; Deborah J Tew; Michelle T Fodero-Tavoletti; Timothy Johanssen; Colin L Masters; Kevin J Barnham; Roberto Cappai
Concentration dependent Cu2+ induced aggregation and dityrosine formation of the Alzheimer's disease amyloid-beta peptide.
Biochemistry 2007;46(10):2881-91.
2006: James A Duce; David P Smith; Rachel E Blake; Peter J Crouch; Qiao-Xin Li; Colin L Masters; Ian A Trounce
Linker histone H1 binds to disease associated amyloid-like fibrils.
Journal of molecular biology 2006;361(3):493-505.
2006: David P Smith; Danielle G Smith; Cyril C Curtain; John F Boas; John R Pilbrow; Giuseppe D Ciccotosto; Tong-Lay Crystal Lau; Deborah J Tew; Keyla Perez; John D Wade; Ashley I Bush; Simon C Drew; Frances Separovic; Colin L Masters; Roberto Cappai; Kevin J Barnham
Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge.
The Journal of biological chemistry 2006;281(22):15145-54.
2005: Roberto Cappai; Su-Ling Leck; Deborah J Tew; Nicholas A Williamson; David P Smith; Denise Galatis; Robyn A Sharples; Cyril C Curtain; Feda E Ali; Robert A Cherny; Janetta G Culvenor; Stephen P Bottomley; Colin L Masters; Kevin J Barnham; Andrew Hill
Dopamine promotes alpha-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(10):1377-9.