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Gary Smith

Research Profile

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Publications

TOP 3
James E Swain; Shuichi Takayama; D Lai; Gary D Smith
Thinking big by thinking small: application of microfluidic technology to improve ART.
Kristopher R Schwab; Gary D Smith; Gregory R Dressler
Arrested spermatogenesis and evidence for DNA damage in PTIP mutant testes.
Yun Seok Heo; Gary D Smith; Charles L Bormann; Lourdes M Cabrera; Shuichi Takayama
Real time culture and analysis of embryo metabolism using a microfluidic device with deformation based actuation.

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All Publications

2013: James E Swain; Shuichi Takayama; D Lai; Gary D Smith
Thinking big by thinking small: application of microfluidic technology to improve ART.
Lab on a chip 2013;13(7):1213-24.
2013: Kristopher R Schwab; Gary D Smith; Gregory R Dressler
Arrested spermatogenesis and evidence for DNA damage in PTIP mutant testes.
Developmental biology 2013;373(1):64-71.
2012: Yun Seok Heo; Gary D Smith; Charles L Bormann; Lourdes M Cabrera; Shuichi Takayama
Real time culture and analysis of embryo metabolism using a microfluidic device with deformation based actuation.
Lab on a chip 2012;12(12):2240-6.
2012: Gary D Smith; Andre Monteiro da Rocha
Advances in embryo culture systems.
Seminars in reproductive medicine 2012;30(3):214-21.
2012: Claudia Gomes; Jeremy Konheim; Mariana Merlini; Eduardo L A Motta; Paulo Serafini; Edmund C Baracat; Gary D Smith
Oocyte meiotic-stage-specific differences in spindle depolymerization in response to temperature changes monitored with polarized field microscopy and immunocytochemistry.
Fertility and sterility 2012;97(3):714-9.
2012: Gary D Smith; Shuichi Takayama; Jason Swain
Rethinking in vitro embryo culture: new developments in culture platforms and potential to improve assisted reproductive technologies.
Biology of reproduction 2012;86(3):62.
2012: Jason Swain; X Xu; L Cabrera; Gary D Smith
Microdrop preparation factors influence culture-media osmolality, which can impair mouse embryo preimplantation development.
Reproductive biomedicine online 2012;24(2):142-7.
2012: André Monteiro da Rocha; Gary D Smith
Culture systems: fluid dynamic embryo culture systems (microfluidics).
Methods in molecular biology (Clifton, N.J.) 2012;912():355-65.
2012: Gary D Smith
Utility of animal models for human embryo culture development: rodents.
Methods in molecular biology (Clifton, N.J.) 2012;912():19-26.
2011: Gary D Smith; Eduardo E Motta; Paulo Serafini
Theoretical and experimental basis of oocyte vitrification.
Reproductive biomedicine online 2011;23(3):298-306.
2011: Himabindu Nandivada; K Sue O'Shea; Gary D Smith; Luis G Villa-Diaz; Paul H Krebsbach; Joerg Lahann
Fabrication of synthetic polymer coatings and their use in feeder-free culture of human embryonic stem cells.
Nature protocols 2011;6(7):1037-43.
2011: Charles L Bormann; Vasantha Padmanabhan; Gary D Smith; Theresa M Lee
Prenatal testosterone and dihydrotestosterone exposure disrupts ovine testicular development.
Reproduction (Cambridge, England) 2011;142(1):167-73.
2011: Jun Ding; Jason Swain; Gary D Smith
Aurora kinase-A regulates microtubule organizing center (MTOC) localization, chromosome dynamics, and histone-H3 phosphorylation in mouse oocytes.
Molecular reproduction and development 2011;78(2):80-90.
2011: Paulo Serafini; Gary D Smith; Eduardo Leme Alves Da Motta; André Monteiro da Rocha; Edmund Chada Baracat
Laboratory methods in the study of endometrial Claudin-4.
Methods in molecular biology (Clifton, N.J.) 2011;762():281-90.
2011: Gary D Smith; Jason Swain; C L Bormann
Microfluidics for gametes, embryos, and embryonic stem cells.
Seminars in reproductive medicine 2011;29(1):5-14.
2010: Robert E Jackson; Charles L Bormann; Pericles A Hassun; André M Rocha; Eduardo L A Motta; Paulo C Serafini; Gary D Smith
Effects of semen storage and separation techniques on sperm DNA fragmentation.
Fertility and sterility 2010;94(7):2626-30.
2010: Gary D Smith; Paulo Serafini; Joyce Fioravanti; Isaac Yadid; Marcio Coslovsky; Pericles Hassun; José Roberto Alegretti; Eduardo L A Motta
Prospective randomized comparison of human oocyte cryopreservation with slow-rate freezing or vitrification.
Fertility and sterility 2010;94(6):2088-95.
2010: Peter E Newburger; Talia N Pindyck; Zhiqing Zhu; Audrey Anna Bolyard; Andrew A G Aprikyan; David C Dale; Gary D Smith; Laurence A Boxer
Cyclic neutropenia and severe congenital neutropenia in patients with a shared ELANE mutation and paternal haplotype: evidence for phenotype determination by modifying genes.
Pediatric blood & cancer 2010;55(2):314-7.
2010: Luis G Villa-Diaz; Jun Ding; Paul H Krebsbach; Joerg Lahann; Himabindu Nandivada; Naiara C Nogueira-de-Souza; K Sue O'Shea; Gary D Smith
Synthetic polymer coatings for long-term growth of human embryonic stem cells.
Nature biotechnology 2010;28(6):581-3.
2010: Ryan T Schulte; Dana A Ohl; Mark Sigman; Gary D Smith
Sperm DNA damage in male infertility: etiologies, assays, and outcomes.
Journal of assisted reproduction and genetics 2010;27(1):3-12.
2009: Paulo Serafini; André Monteiro Da Rocha; Cyntia Aparecida Bueno De Toledo Osório; Gary D Smith; Pericles Assad Hassun; Ismael Guerreiro Dale Cotrim Guerreiro da Silva; Eduardo Leme Alves Da Motta; Edmund C Baracat
Protein profile of the luteal phase endometrium by tissue microarray assessment.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2009;25(9):587-92.
2009: Luis Gerardo Villa-Diaz; Yu-Suke Torisawa; Tomoyuki Uchida; Jun Ding; Naiara Correa Nogueira-de-Souza; K Sue O'Shea; Shuichi Takayama; Gary D Smith
Microfluidic culture of single human embryonic stem cell colonies.
Lab on a chip 2009;9(12):1749-55.
2009: Eduardo L Motta; Gary D Smith; Paulo C Serafini; Marcio Coslovsky; Pericles Hassun; Andre M Rocha; Isaac Yadid
Human choriogonadotropin prior to controlled ovarian stimulation and in vitro fertilization improves implantation, and pregnancy rates.
Journal of assisted reproduction and genetics 2009;26(6):305-11.
2009: Luis G Villa-Diaz; Crystal Pacut; Nicole A Slawny; Jun Ding; K Sue O'Shea; Gary D Smith
Analysis of the factors that limit the ability of feeder cells to maintain the undifferentiated state of human embryonic stem cells.
Stem cells and development 2009;18(4):641-51.
2009: Paulo C Serafini; I D C G Silva; Gary D Smith; Eduardo L A Motta; Andreia Maria Camargos Rocha; Edmund C Baracat
Endometrial claudin-4 and leukemia inhibitory factor are associated with assisted reproduction outcome.
Reproductive biology and endocrinology : RB&E 2009;7():30.
2008: Meghan B Oakes; Claudia Messias Gomes; Joyce Fioravanti; Paulo Serafini; Eduardo L A Motta; Gary D Smith
A case of oocyte and embryo vitrification resulting in clinical pregnancy.
Fertility and sterility 2008;90(5):2013.e5-8.
2008: Claudia Messias Gomes; Cristine Ane Silva E Silva; Nicole Acevedo; Edmund Baracat; Paulo Serafini; Gary D Smith
Influence of vitrification on mouse metaphase II oocyte spindle dynamics and chromatin alignment.
Fertility and sterility 2008;90(4 Suppl):1396-404.
2008: Ryan T Schulte; Laura M Keller; Melissa R Hiner; Dana A Ohl; Gary D Smith
Temporal decreases in sperm motility: which patients should have motility checked at both 1 and 2 hours after collection?
Journal of andrology 2008;29(5):558-63.
2008: Jason Swain; Jun Ding; Jingwen Wu; Gary D Smith
Regulation of spindle and chromatin dynamics during early and late stages of oocyte maturation by aurora kinases.
Molecular human reproduction 2008;14(5):291-9.
2008: Shahryar K Kavoussi; Senait Fisseha; Yolanda R Smith; Gary D Smith; Gregory M Christman; L April Gago
Oocyte cryopreservation in a woman with mosaic Turner syndrome: a case report.
The Journal of reproductive medicine 2008;53(3):223-6.
2007: Mei-yu Yu; Lixin Song; Amy D Seetoo; Cuijuan Cai; Gary D Smith; Deborah Oakley
Culturally competent training program: a key to training lay health advisors for promoting breast cancer screening.
Health education & behavior : the official publication of the Society for Public Health Education 2007;34(6):928-41.
2007: David S Morris; Rodney L Dunn; Timothy G Schuster; Dana A Ohl; Gary D Smith
Ideal culture time for improvement in sperm motility from testicular sperm aspirates of men with azoospermia.
The Journal of urology 2007;178(5):2087-91; discussion 2091.
2007: Nicole Acevedo; Jun Ding; Gary D Smith
Insulin signaling in mouse oocytes.
Biology of reproduction 2007;77(5):872-9.
2007: Gary D Smith; Shuichi Takayama
Gamete and embryo isolation and culture with microfluidics.
Theriogenology 2007;68 Suppl 1():S190-5.
2007: Jason Swain; Jun Ding; David L Brautigan; Emma Villa-Moruzzi; Gary D Smith
Proper chromatin condensation and maintenance of histone H3 phosphorylation during mouse oocyte meiosis requires protein phosphatase activity.
Biology of reproduction 2007;76(4):628-38.
2007: Yun Seok Heo; Lourdes M Cabrera; Jonathan Song; Nobuyuki Futai; Yi-Chung Tung; Gary D Smith; Shuichi Takayama
Characterization and resolution of evaporation-mediated osmolality shifts that constrain microfluidic cell culture in poly(dimethylsiloxane) devices.
Analytical chemistry 2007;79(3):1126-34.
2007: Herkanwal S Khaira; Timothy G Schuster; Wen-Xiang Zhang; Rodney Dunn; Gary D Smith; Dana A Ohl
Epididymal obstruction results in isolated sperm heads in post-vasectomy rats.
International journal of andrology 2007;30(1):56-60.
2007: Nicole Acevedo; Xia Wang; Rodney L Dunn; Gary D Smith
Glycogen synthase kinase-3 regulation of chromatin segregation and cytokinesis in mouse preimplantation embryos.
Molecular reproduction and development 2007;74(2):178-88.
2007: Jason Swain; Gary D Smith
Reversible phosphorylation and regulation of mammalian oocyte meiotic chromatin remodeling and segregation.
Society of Reproduction and Fertility supplement 2007;63():343-58.
2006: Gregory B Less; Nathan W Ockwig; Paul G Rasmussen; Gary D Smith; Laura M Keller; John C Drach
Vanadium complex of 2-(2'-Pyridyl)-4,5-dicyanoimidazole showing spermicidal and cytotoxic properties.
Inorganic chemistry 2006;45(18):7105-10.
2006: Roland P S Kwok; Xiao-Tie Liu; Gary D Smith
Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.
Molecular reproduction and development 2006;73(7):885-94.
2006: Jason M Wu; Yaokuang Chung; Kimberly J Belford; Gary D Smith; Shuichi Takayama; Joerg Lahann
A surface-modified sperm sorting device with long-term stability.
Biomedical microdevices 2006;8(2):99-107.
2006: Ronald S Suh; Xiaoyue Zhu; Nandita Phadke; Dana A Ohl; Shuichi Takayama; Gary D Smith
IVF within microfluidic channels requires lower total numbers and lower concentrations of sperm.
Human reproduction (Oxford, England) 2006;21(2):477-83.
2006: Yaokuang Chung; Xiaoyue Zhu; Wei Gu; Gary D Smith; Shuichi Takayama
Microscale integrated sperm sorter.
Methods in molecular biology (Clifton, N.J.) 2006;321():227-44.
2005: Ronald S Suh; Shuichi Takayama; Gary D Smith
Microfluidic applications for andrology.
Journal of andrology 2005;26(6):664-70.
2005: Herkanwal S Khaira; Derek McLean; Dana A Ohl; Gary D Smith
Spermatogonial stem cell isolation, storage, and transplantation.
Journal of andrology 2005;26(4):442-50.
2005: Gary D Smith
Andrology: pursuit of the scientific trinity.
Journal of andrology 2005;26(3):304-5.
2005: Nicole Acevedo; Gary D Smith
Oocyte-specific gene signaling and its regulation of mammalian reproductive potential.
Frontiers in bioscience : a journal and virtual library 2005;10():2335-45.
2004: Xia Wang; Jason Swain; Mathieu Bollen; Xiao-Tie Liu; Dana A Ohl; Gary D Smith
Endogenous regulators of protein phosphatase-1 during mouse oocyte development and meiosis.
Reproduction (Cambridge, England) 2004;128(5):493-502.
2004: Jason Swain; Rodney L Dunn; Daniel S McConnell; Janis Gonzalez-Martinez; Gary D Smith
Direct effects of leptin on mouse reproductive function: regulation of follicular, oocyte, and embryo development.
Biology of reproduction 2004;71(5):1446-52.
2004: Gary D Smith; Cristine Ane Silva E Silva
Developmental consequences of cryopreservation of mammalian oocytes and embryos.
Reproductive biomedicine online 2004;9(2):171-8.
2004: Brian Eisner; Timothy G Schuster; Phillip Eugene Rodgers; Muzammil Ahmed; Gary J Faerber; Gary D Smith; Dana A Ohl
A randomized clinical trial of the effect of intraoperative saline perfusion on postvasectomy azoospermia.
Annals of family medicine 2004;2(3):221-3.
2004: Fawaz Alkazaleh; Sandra Viero; Michal J Simchen; M Walker; Gary D Smith; C Laskin; Rory Windrim; John Kingdom
Ultrasound diagnosis of severe thrombotic placental damage in the second trimester: an observational study.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2004;23(5):472-6.
2004: Marcia Leonard; Karen Hammelef; Gary D Smith
Fertility considerations, counseling, and semen cryopreservation for males prior to the initiation of cancer therapy.
Clinical journal of oncology nursing 2004;8(2):127-31, 145.
2003: Allen W Ayres; Daniel W Carr; Daniel S McConnell; Richard W Lieberman; Gary D Smith
Expression and intracellular localization of protein phosphatases 2A and 2B, protein kinase a, A-Kinase anchoring protein (AKAP79), and binding of the regulatory (RII) subunit of protein kinase a to AKAP79 in human myometrium.
Journal of the Society for Gynecologic Investigation 2003;10(7):428-37.
2003: Ronald S Suh; Nandita Phadke; Dana A Ohl; Shuichi Takayama; Gary D Smith
Rethinking gamete/embryo isolation and culture with microfluidics.
Human reproduction update 2003;9(5):451-61.
2003: Timothy G Schuster; Brenda Cho; Laura M Keller; Shuichi Takayama; Gary D Smith
Isolation of motile spermatozoa from semen samples using microfluidics.
Reproductive biomedicine online 2003;7(1):75-81.
2003: Timothy G Schuster; Kathryn Hickner-Cruz; Dana A Ohl; Edward Goldman; Gary D Smith
Legal considerations for cryopreservation of sperm and embryos.
Fertility and sterility 2003;80(1):61-6.
2003: Jason Swain; Xia Wang; Thomas L Saunders; Rodney Dunn; Gary D Smith
Specific inhibition of mouse oocyte nuclear protein phosphatase-1 stimulates germinal vesicle breakdown.
Molecular reproduction and development 2003;65(1):96-103.
2003: Brenda S Cho; Timothy G Schuster; Xiaoyue Zhu; David Chang; Gary D Smith; Shuichi Takayama
Passively driven integrated microfluidic system for separation of motile sperm.
Analytical chemistry 2003;75(7):1671-5.
2003: Timothy G Schuster; Laura M Keller; Rodney L Dunn; Dana A Ohl; Gary D Smith
Ultra-rapid freezing of very low numbers of sperm using cryoloops.
Human reproduction (Oxford, England) 2003;18(4):788-95.
2003: Xia Wang; Xiao-Tie Liu; Rodney Dunn; Dana A Ohl; Gary D Smith
Glycogen synthase kinase-3 regulates mouse oocyte homologue segregation.
Molecular reproduction and development 2003;64(1):96-105.
2002: Lawrence C Layman; David P Cohen; Jun Xie; Gary D Smith
Clinical phenotype and infertility treatment in a male with hypogonadotropic hypogonadism due to mutations Ala129Asp/Arg262Gln of the gonadotropin-releasing hormone receptor.
Fertility and sterility 2002;78(6):1317-20.
2002: David C Miller; Brent K Hollenbeck; Gary D Smith; John F Randolph Jr; Gregory M Christman; Yolanda R Smith; Dan I Lebovic; Dana A Ohl
Processed total motile sperm count correlates with pregnancy outcome after intrauterine insemination.
Urology 2002;60(3):497-501.
2002: Qing Lu; Gary D Smith; Da-Yuan Chen; Zhi-Ming Han; Qing-Yuan Sun
Activation of protein kinase C induces mitogen-activated protein kinase dephosphorylation and pronucleus formation in rat oocytes.
Biology of reproduction 2002;67(1):64-9.
2002: Gary D Smith; Leslie M Jackson; Douglas L Foster
Leptin regulation of reproductive function and fertility.
Theriogenology 2002;57(1):73-86.
2002: Qing Lu; Rodney L Dunn; Rowena Angeles; Gary D Smith
Regulation of spindle formation by active mitogen-activated protein kinase and protein phosphatase 2A during mouse oocyte meiosis.
Biology of reproduction 2002;66(1):29-37.
2001: Gary D Smith
In vitro maturation of oocytes.
Current women's health reports 2001;1(2):143-51.
2001: Qing Lu; Gary D Smith; Da-Yuan Chen; Z Yang; Zhi-Ming Han; Heide Schatten; Qing-Yuan Sun
Phosphorylation of mitogen-activated protein kinase is regulated by protein kinase C, cyclic 3',5'-adenosine monophosphate, and protein phosphatase modulators during meiosis resumption in rat oocytes.
Biology of reproduction 2001;64(5):1444-50.
2001: Joseph Welk; Amanda Charlesworth; Gary D Smith; Angus M MacNicol
Identification and characterization of the gene encoding human cytoplasmic polyadenylation element binding protein.
Gene 2001;263(1-2):113-20.
2000: Gary D Smith; X T Liu; Mark Phillippe
Divergence in murine myometrium spontaneous and oxytocin-stimulated contractile responses to serine/threonine protein phosphatase-1 inhibition.
Biology of reproduction 2000;63(3):781-8.
1999: Gary D Smith; Ian M Steele; Randall B Barnes; L A Levine
Identification of seminiferous tubule aberrations and a low incidence of testicular microliths associated with the development of azoospermia.
Fertility and sterility 1999;72(3):467-71.
1999: Gary D Smith; Don P Wolf; K C Trautman; S Vijayaraghavan
Motility potential of macaque epididymal sperm: the role of protein phosphatase and glycogen synthase kinase-3 activities.
Journal of andrology 1999;20(1):47-53.
1998: Gary D Smith; Annamma Sadhu; S Mathies; D P Wolf
Characterization of protein phosphatases in mouse oocytes.
Developmental biology 1998;204(2):537-49.
1998: Gary D Smith; Annamma Sadhu; D P Wolf
Transient exposure of rhesus macaque oocytes to calyculin-A and okadaic acid stimulates germinal vesicle breakdown permitting subsequent development and fertilization.
Biology of reproduction 1998;58(4):880-6.
1998: Kimberly C Sippel; Rebecca E. Fraioli; Gary D Smith; M E Schalkoff; Joanne Sutherland; B L Gallie; Thaddeus P Dryja
Frequency of somatic and germ-line mosaicism in retinoblastoma: implications for genetic counseling.
American journal of human genetics 1998;62(3):610-9.
1996: B M Alak; Gary D Smith; T K Woodruff; Richard L Stouffer; Don P Wolf
Enhancement of primate oocyte maturation and fertilization in vitro by inhibin A and activin A.
Fertility and sterility 1996;66(4):646-53.
1996: Gary D Smith; Don P Wolf; K C Trautman; E F da Cruz e Silva; Paul Greengard; S Vijayaraghavan
Primate sperm contain protein phosphatase 1, a biochemical mediator of motility.
Biology of reproduction 1996;54(3):719-27.
1996: S Vijayaraghavan; D T Stephens; K Trautman; Gary D Smith; B Khatra; E F da Cruz e Silva; Paul Greengard
Sperm motility development in the epididymis is associated with decreased glycogen synthase kinase-3 and protein phosphatase 1 activity.
Biology of reproduction 1996;54(3):709-18.
1986: B L Carter; C E Driscoll; Gary D Smith
Theophylline clearance during pregnancy.
Obstetrics and gynecology 1986;68(4):555-9.