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Gerald Smith
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Research Profile (preview)
Physiology
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Chemicals & Drugs
Genes & Molecular Sequences
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Network (preview)
17
Taylor, Andrew
10
Cromie, Gareth
7
Farah, Joseph
7
Amundsen, Susan
7
Hyppa, Randy
6
Steiner, Walter
5
Schultz, Dennis
5
Davis, Luther
3
Ellermeier, Chad
2
Martín-Castellanos, Cristina
2
Moreno, Sergio
1
Russell, Paul
1
Salama, Nina
1
San-Segundo, Pedro
1
Shanahan, Paul
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All Publications
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2009: Milman Neta; Higuchi Emily; Smith Gerald R
Meiotic DNA double-strand break repair requires two nucleases, MRN and Ctp1, to produce a single size class of Rec12 (Spo11)-oligonucleotide complexes.
Molecular and cellular biology 2009;29(22):5998-6005.
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2009: Farah Joseph A; Cromie Gareth A; Smith Gerald R
Ctp1 and Exonuclease 1, alternative nucleases regulated by the MRN complex, are required for efficient meiotic recombination.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(23):9356-61.
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2009: Hyppa Randy W; Smith Gerald R
Using Schizosaccharomyces pombe meiosis to analyze DNA recombination intermediates.
Methods in molecular biology (Clifton, N.J.) 2009;557():235-52.
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2009: Smith Gerald R
Genetic analysis of meiotic recombination in Schizosaccharomyces pombe.
Methods in molecular biology (Clifton, N.J.) 2009;557():65-76.
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2008: Hyppa Randy W; Cromie Gareth A; Smith Gerald R
Indistinguishable landscapes of meiotic DNA breaks in rad50+ and rad50S strains of fission yeast revealed by a novel rad50+ recombination intermediate.
PLoS genetics 2008;4(11):e1000267.
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2008: Smith Gerald R
Meeting DNA palindromes head-to-head.
Genes & development 2008;22(19):2612-20.
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2008: Amundsen Susan K; Fero Jutta; Hansen Lori M; Cromie Gareth A; Solnick Jay V; Smith Gerald R; Salama Nina R
Helicobacter pylori AddAB helicase-nuclease and RecA promote recombination-related DNA repair and survival during stomach colonization.
Molecular microbiology 2008;69(4):994-1007.
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2008: Cromie Gareth A; Hyppa Randy W; Smith Gerald R
The fission yeast BLM homolog Rqh1 promotes meiotic recombination.
Genetics 2008;179(3):1157-67.
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2008: Davis Luther; Rozalén Ana E; Moreno Sergio; Smith Gerald R; Martín-Castellanos Cristina
Rec25 and Rec27, novel linear-element components, link cohesin to meiotic DNA breakage and recombination.
Current biology : CB 2008;18(11):849-54.
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2007: Amundsen Susan K; Taylor Andrew F; Reddy Manjula; Smith Gerald R
Intersubunit signaling in RecBCD enzyme, a complex protein machine regulated by Chi hot spots.
Genes & development 2007;21(24):3296-307.
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2007: Cromie Gareth A; Smith Gerald R
Branching out: meiotic recombination and its regulation.
Trends in cell biology 2007;17(9):448-55.
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2007: Cromie Gareth A; Hyppa Randy W; Cam Hugh P; Farah Joseph A; Grewal Shiv I S; Smith Gerald R
A discrete class of intergenic DNA dictates meiotic DNA break hotspots in fission yeast.
PLoS genetics 2007;3(8):e141.
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2007: Amundsen Susan K; Smith Gerald R
Chi hotspot activity in Escherichia coli without RecBCD exonuclease activity: implications for the mechanism of recombination.
Genetics 2007;175(1):41-54.
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2006: Cromie Gareth A; Hyppa Randy W; Taylor Andrew F; Zakharyevich Kseniya; Hunter Neil; Smith Gerald R
Single Holliday junctions are intermediates of meiotic recombination.
Cell 2006;127(6):1167-78.
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2006: Davis Luther; Smith Gerald R
The meiotic bouquet promotes homolog interactions and restricts ectopic recombination in Schizosaccharomyces pombe.
Genetics 2006;174(1):167-77.
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2005: Farah Joseph A; Cromie Gareth; Davis Luther; Steiner Walter W; Smith Gerald R
Activation of an alternative, rec12 (spo11)-independent pathway of fission yeast meiotic recombination in the absence of a DNA flap endonuclease.
Genetics 2005;171(4):1499-511.
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2005: Martín-Castellanos Cristina; Blanco Miguel; Rozalén Ana E; Pérez-Hidalgo Livia; García Ana I; Conde Francisco; Mata Juan; Ellermeier Chad; Davis Luther; San-Segundo Pedro; Smith Gerald R; Moreno Sergio
A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.
Current biology : CB 2005;15(22):2056-62.
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2005: Steiner Walter W; Smith Gerald R
Natural meiotic recombination hot spots in the Schizosaccharomyces pombe genome successfully predicted from the simple sequence motif M26.
Molecular and cellular biology 2005;25(20):9054-62.
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2005: Ellermeier Chad; Smith Gerald R
Cohesins are required for meiotic DNA breakage and recombination in Schizosaccharomyces pombe.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(31):10952-7.
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2005: Davis Luther; Smith Gerald R
Dynein promotes achiasmate segregation in Schizosaccharomyces pombe.
Genetics 2005;170(2):581-90.
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2005: Steiner Walter W; Smith Gerald R
Optimizing the nucleotide sequence of a meiotic recombination hotspot in Schizosaccharomyces pombe.
Genetics 2005;169(4):1973-83.
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2005: Farah Joseph A; Cromie Gareth; Steiner Walter W; Smith Gerald R
A novel recombination pathway initiated by the Mre11/Rad50/Nbs1 complex eliminates palindromes during meiosis in Schizosaccharomyces pombe.
Genetics 2005;169(3):1261-74.
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2005: Cromie Gareth A; Rubio Claudia A; Hyppa Randy W; Smith Gerald R
A natural meiotic DNA break site in Schizosaccharomyces pombe is a hotspot of gene conversion, highly associated with crossing over.
Genetics 2005;169(2):595-605.
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2004: Ellermeier Chad; Schmidt Henning; Smith Gerald R
Swi5 acts in meiotic DNA joint molecule formation in Schizosaccharomyces pombe.
Genetics 2004;168(4):1891-8.
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2004: Young Jennifer A; Hyppa Randy W; Smith Gerald R
Conserved and nonconserved proteins for meiotic DNA breakage and repair in yeasts.
Genetics 2004;167(2):593-605.
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2004: Smith Gerald R
How homologous recombination is initiated: unexpected evidence for single-strand nicks from v(d)j site-specific recombination.
Cell 2004;117(2):146-8.
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2003: Smith Gerald R; Boddy Michael N; Shanahan Paul; Russell Paul
Fission yeast Mus81.Eme1 Holliday junction resolvase is required for meiotic crossing over but not for gene conversion.
Genetics 2003;165(4):2289-93.
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2003: Taylor Andrew F; Smith Gerald R
RecBCD enzyme is a DNA helicase with fast and slow motors of opposite polarity.
Nature 2003;423(6942):889-93.
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2003: Amundsen Susan K; Smith Gerald R
Interchangeable parts of the Escherichia coli recombination machinery.
Cell 2003;112(6):741-4.
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2002: Amundsen Susan K; Taylor Andrew F; Smith Gerald R
A domain of RecC required for assembly of the regulatory RecD subunit into the Escherichia coli RecBCD holoenzyme.
Genetics 2002;161(2):483-92.
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2002: Farah Joseph A; Hartsuiker Edgar; Mizuno Ken-Ichi; Ohta Kunihiro; Smith Gerald R
A 160-bp palindrome is a Rad50.Rad32-dependent mitotic recombination hotspot in Schizosaccharomyces pombe.
Genetics 2002;161(1):461-8.
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2002: Steiner Walter W; Schreckhise Randall W; Smith Gerald R
Meiotic DNA breaks at the S. pombe recombination hot spot M26.
Molecular cell 2002;9(4):847-55.
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2002: Young Jennifer A; Schreckhise Randall W; Steiner Walter W; Smith Gerald R
Meiotic recombination remote from prominent DNA break sites in S. pombe.
Molecular cell 2002;9(2):253-63.
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2001: Davis L; Smith G R
Meiotic recombination and chromosome segregation in Schizosaccharomyces pombe.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(15):8395-402.
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2001: Smith G R
Homologous recombination near and far from DNA breaks: alternative roles and contrasting views.
Annual review of genetics 2001;35():243-74.
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2000: Fox M E; Yamada T; Ohta K; Smith G R
A family of cAMP-response-element-related DNA sequences with meiotic recombination hotspot activity in Schizosaccharomyces pombe.
Genetics 2000;156(1):59-68.
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2000: Amundsen S K; Taylor A F; Smith G R
The RecD subunit of the Escherichia coli RecBCD enzyme inhibits RecA loading, homologous recombination, and DNA repair.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):7399-404.
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2000: Cervantes M D; Farah J A; Smith G R
Meiotic DNA breaks associated with recombination in S. pombe.
Molecular cell 2000;5(5):883-8.
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1999: Taylor A F; Smith G R
Regulation of homologous recombination: Chi inactivates RecBCD enzyme by disassembly of the three subunits.
Genes & development 1999;13(7):890-900.
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1998: Ding R; Smith G R
Global control of meiotic recombination genes by Schizosaccharomyces pombe rec16 (rep1).
Molecular & general genetics : MGG 1998;258(6):663-70.
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1998: Amundsen S K; Taylor A F; Smith G R
A stimulatory RNA associated with RecBCD enzyme.
Nucleic acids research 1998;26(9):2125-31.
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1998: Fox M E; Smith G R
Control of meiotic recombination in Schizosaccharomyces pombe.
Progress in nucleic acid research and molecular biology 1998;61():345-78.
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1997: Farah J A; Smith G R
The RecBCD enzyme initiation complex for DNA unwinding: enzyme positioning and DNA opening.
Journal of molecular biology 1997;272(5):699-715.
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1997: Evans D H; Li Y F; Fox M E; Smith G R
A WD repeat protein, Rec14, essential for meiotic recombination in Schizosaccharomyces pombe.
Genetics 1997;146(4):1253-64.
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1997: Fox M E; Virgin J B; Metzger J; Smith G R
Position- and orientation-independent activity of the Schizosaccharomyces pombe meiotic recombination hot spot M26.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7446-51.
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1997: Li Y F; Smith G R
The Schizosaccharomyces pombe rec16 gene product regulates multiple meiotic events.
Genetics 1997;146(1):57-67.
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1997: Dabert P; Smith G R
Gene replacement with linear DNA fragments in wild-type Escherichia coli: enhancement by Chi sites.
Genetics 1997;145(4):877-89.
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1997: Li Y F; Numata M; Wahls W P; Smith G R
Region-specific meiotic recombination in Schizosaccharomyces pombe: the rec11 gene.
Molecular microbiology 1997;23(5):869-78.
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1996: Szankasi P; Smith G R
Requirement of S. pombe exonuclease II, a homologue of S. cerevisiae Sep1, for normal mitotic growth and viability.
Current genetics 1996;30(4):284-93.
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1995: Taylor A F; Smith G R
Strand specificity of nicking of DNA at Chi sites by RecBCD enzyme. Modulation by ATP and magnesium levels.
The Journal of biological chemistry 1995;270(41):24459-67.
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1995: Taylor A F; Smith G R
Monomeric RecBCD enzyme binds and unwinds DNA.
The Journal of biological chemistry 1995;270(41):24451-8.
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1995: Virgin J B; Metzger J; Smith G R
Active and inactive transplacement of the M26 recombination hotspot in Schizosaccharomyces pombe.
Genetics 1995;141(1):33-48.
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1995: Lin Y; Smith G R
An intron-containing meiosis-induced recombination gene, rec15, of Schizosaccharomyces pombe.
Molecular microbiology 1995;17(3):439-48.
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1995: Lin Y; Smith G R
Molecular cloning of the meiosis-induced rec10 gene of Schizosaccharomyces pombe.
Current genetics 1995;27(5):440-6.
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1995: Szankasi P; Smith G R
A role for exonuclease I from S. pombe in mutation avoidance and mismatch correction.
Science (New York, N.Y.) 1995;267(5201):1166-9.
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1995: Smith G R; Amundsen S K; Dabert P; Taylor A F
The initiation and control of homologous recombination in Escherichia coli.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1995;347(1319):13-20.
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1994: Wahls W P; Smith G R
A heteromeric protein that binds to a meiotic homologous recombination hot spot: correlation of binding and hot spot activity.
Genes & development 1994;8(14):1693-702.
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1994: Smith G R
Hotspots of homologous recombination.
Experientia 1994;50(3):234-41.
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1994: Lin Y; Smith G R
Transient, meiosis-induced expression of the rec6 and rec12 genes of Schizosaccharomyces pombe.
Genetics 1994;136(3):769-79.
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1994: DeVeaux L C; Smith G R
Region-specific activators of meiotic recombination in Schizosaccharomyces pombe.
Genes & development 1994;8(2):203-10.
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1993: Wahls W P; Song J M; Smith G R
Single-stranded DNA binding activity of C1-tetrahydrofolate synthase enzymes.
The Journal of biological chemistry 1993;268(32):23792-8.
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1993: Ganesan S; Smith G R
Strand-specific binding to duplex DNA ends by the subunits of the Escherichia coli RecBCD enzyme.
Journal of molecular biology 1993;229(1):67-78.
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1992: Holbeck S L; Smith G R
Chi enhances heteroduplex DNA levels during recombination.
Genetics 1992;132(4):879-91.
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1992: Lin Y; Larson K L; Dorer R; Smith G R
Meiotically induced rec7 and rec8 genes of Schizosaccharomyces pombe.
Genetics 1992;132(1):75-85.
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1992: Szankasi P; Smith G R
A single-stranded DNA exonuclease from Schizosaccharomyces pombe.
Biochemistry 1992;31(29):6769-73.
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1992: Taylor A F; Smith G R
RecBCD enzyme is altered upon cutting DNA at a chi recombination hotspot.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(12):5226-30.
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1992: Szankasi P; Smith G R
A DNA exonuclease induced during meiosis of Schizosaccharomyces pombe.
The Journal of biological chemistry 1992;267(5):3014-23.
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1992: De Veaux L C; Hoagland N A; Smith G R
Seventeen complementation groups of mutations decreasing meiotic recombination in Schizosaccharomyces pombe.
Genetics 1992;130(2):251-62.
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1992: Ponticelli A S; Smith G R
Chromosomal context dependence of a eukaryotic recombinational hot spot.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(1):227-31.
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1991: Smith G R
Conjugational recombination in E. coli: myths and mechanisms.
Cell 1991;64(1):19-27.
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1990: Amundsen S K; Neiman A M; Thibodeaux S M; Smith G R
Genetic dissection of the biochemical activities of RecBCD enzyme.
Genetics 1990;126(1):25-40.
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1990: Taylor A F; Smith G R
Action of RecBCD enzyme on cruciform DNA.
Journal of molecular biology 1990;211(1):117-34.
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1989: McKittrick N H; Smith G R
Activation of Chi recombinational hotspots by RecBCD-like enzymes from enteric bacteria.
Journal of molecular biology 1989;210(3):485-95.
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1989: Ponticelli A S; Smith G R
Meiotic recombination-deficient mutants of Schizosaccharomyces pombe.
Genetics 1989;123(1):45-54.
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1989: Smith G R
Homologous recombination in E. coli: multiple pathways for multiple reasons.
Cell 1989;58(5):807-9.
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1989: Cheng K C; Smith G R
Distribution of Chi-stimulated recombinational exchanges and heteroduplex endpoints in phage lambda.
Genetics 1989;123(1):5-17.
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1989: Braedt G; Smith G R
Strand specificity of DNA unwinding by RecBCD enzyme.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(3):871-5.
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1989: Smith G R
Homologous recombination in prokaryotes: enzymes and controlling sites.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1989;31(2):520-7.
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1988: Ponticelli A S; Sena E P; Smith G R
Genetic and physical analysis of the M26 recombination hotspot of Schizosaccharomyces pombe.
Genetics 1988;119(3):491-7.
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1987: Cheng K C; Smith G R
Cutting of chi-like sequences by the RecBCD enzyme of Escherichia coli.
Journal of molecular biology 1987;194(4):747-50.
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1987: Smith G R
Mechanism and control of homologous recombination in Escherichia coli.
Annual review of genetics 1987;21():179-201.
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1986: Amundsen S K; Taylor A F; Chaudhury A M; Smith G R
recD: the gene for an essential third subunit of exonuclease V.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(15):5558-62.
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1986: Smith G R; Roberts C M; Schultz D W
Activity of Chi recombinational hotspots in Salmonella typhimurium.
Genetics 1986;112(3):429-39.
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1985: Taylor A F; Schultz D W; Ponticelli A S; Smith G R
RecBC enzyme nicking at Chi sites during DNA unwinding: location and orientation-dependence of the cutting.
Cell 1985;41(1):153-63.
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1985: Ponticelli A S; Schultz D W; Taylor A F; Smith G R
Chi-dependent DNA strand cleavage by RecBC enzyme.
Cell 1985;41(1):145-51.
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1984: Smith G R; Amundsen S K; Chaudhury A M; Cheng K C; Ponticelli A S; Roberts C M; Schultz D W; Taylor A F
Roles of RecBC enzyme and chi sites in homologous recombination.
Cold Spring Harbor symposia on quantitative biology 1984;49():485-95.
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1983: Schultz D W; Taylor A F; Smith G R
Escherichia coli RecBC pseudorevertants lacking chi recombinational hotspot activity.
Journal of bacteriology 1983;155(2):664-80.
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