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Zamal Ahmed

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Kin Man Suen; Chi-Chuan Lin; Fernando A Melo; Zamal Ahmed; Stefan T Arold; Swathi Arur; Eleanor R Biggs; Melanie N Drake; Roger George; John E Ladbury
Interaction with Shc prevents aberrant Erk activation in the absence of extracellular stimuli.
Zamal Ahmed; James A Levitt; Chi-Chuan Lin; Fernando A Melo; Kin M Suen; Klaus Suhling; John E Ladbury
Grb2 controls phosphorylation of FGFR2 by inhibiting receptor kinase and Shp2 phosphatase activity.
Chi-Chuan Lin; Fernando A Melo; Loren J Stagg; Kin M Suen; Zamal Ahmed; Stefan T Arold; Ragini Ghosh; John Kirkpatrick; John E Ladbury
Inhibition of basal FGF receptor signaling by dimeric Grb2.

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All Publications

2013: Kin Man Suen; Chi-Chuan Lin; Fernando A Melo; Zamal Ahmed; Stefan T Arold; Swathi Arur; Eleanor R Biggs; Melanie N Drake; Roger George; John E Ladbury
Interaction with Shc prevents aberrant Erk activation in the absence of extracellular stimuli.
Nature structural & molecular biology 2013;20(5):620-7.
2013: Zamal Ahmed; James A Levitt; Chi-Chuan Lin; Fernando A Melo; Kin M Suen; Klaus Suhling; John E Ladbury
Grb2 controls phosphorylation of FGFR2 by inhibiting receptor kinase and Shp2 phosphatase activity.
The Journal of cell biology 2013;200(4):493-504.
2012: Chi-Chuan Lin; Fernando A Melo; Loren J Stagg; Kin M Suen; Zamal Ahmed; Stefan T Arold; Ragini Ghosh; John Kirkpatrick; John E Ladbury
Inhibition of basal FGF receptor signaling by dimeric Grb2.
Cell 2012;149(7):1514-24.
2010: Claire N Stevens; Ann-Marie Simeone; Susan John; Zamal Ahmed; Orso M Lucherini; Cosima T Baldari; John E Ladbury
T-cell receptor early signalling complex activation in response to interferon-alpha receptor stimulation.
The Biochemical journal 2010;428(3):429-37.
2010: Zamal Ahmed; Roger George; Chi-Chuan Lin; Kin Man Suen; James A Levitt; Klaus Suhling; John E Ladbury
Direct binding of Grb2 SH3 domain to FGFR2 regulates SHP2 function.
Cellular signalling 2010;22(1):23-33.
2009: R George; H-L Chan; Zamal Ahmed; K M Suen; C N Stevens; J A Levitt; Klaus Suhling; J Timms; John E Ladbury
A complex of Shc and Ran-GTPase localises to the cell nucleus.
Cellular and molecular life sciences : CMLS 2009;66(4):711-20.
2008: Annika C Schüller; Zamal Ahmed; James A Levitt; Kin M Suen; Klaus Suhling; John E Ladbury
Indirect recruitment of the signalling adaptor Shc to the fibroblast growth factor receptor 2 (FGFR2).
The Biochemical journal 2008;416(2):189-99.
2008: Zamal Ahmed; Annika C Schüller; Klaus Suhling; Carolyn Tregidgo; John E Ladbury
Extracellular point mutations in FGFR2 elicit unexpected changes in intracellular signalling.
The Biochemical journal 2008;413(1):37-49.
2008: Annika C Schüller; Zamal Ahmed; John E Ladbury
Extracellular point mutations in FGFR2 result in elevated ERK1/2 activation and perturbation of neuronal differentiation.
The Biochemical journal 2008;410(1):205-11.
2005: Zamal Ahmed; Carolyn A Beeton; Mark A Williams; Darran Clements; Cosima T Baldari; John E Ladbury
Distinct spatial and temporal distribution of ZAP70 and Lck following stimulation of interferon and T-cell receptors.
Journal of molecular biology 2005;353(5):1001-10.
2003: Zamal Ahmed; Tahir S Pillay
Adapter protein with a pleckstrin homology (PH) and an Src homology 2 (SH2) domain (APS) and SH2-B enhance insulin-receptor autophosphorylation, extracellular-signal-regulated kinase and phosphoinositide 3-kinase-dependent signalling.
The Biochemical journal 2003;371(Pt 2):405-12.
2001: Zamal Ahmed; Tahir S Pillay
Functional effects of APS and SH2-B on insulin receptor signalling.
Biochemical Society transactions 2001;29(Pt 4):529-34.
2000: Zamal Ahmed; B J Smith; Tahir S Pillay
The APS adapter protein couples the insulin receptor to the phosphorylation of c-Cbl and facilitates ligand-stimulated ubiquitination of the insulin receptor.
FEBS letters 2000;475(1):31-4.
1999: Zamal Ahmed; B J Smith; K Kotani; P Wilden; Tahir S Pillay
APS, an adapter protein with a PH and SH2 domain, is a substrate for the insulin receptor kinase.
The Biochemical journal 1999;341 ( Pt 3)():665-8.