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Jeffrey Smith

Research Profile

Chemicals & Drugs

Living Beings

Saccharomyces cerevisiae

Physiology

Genes & Molecular Sequences

Genes, Fungal

Anatomy

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Publications

TOP 3
Julie M McClure; Nazif Maqani; Margaret B Wierman; Jeffrey S Smith
Isonicotinamide enhances Sir2 protein-mediated silencing and longevity in yeast by raising intracellular NAD+ concentration.
Sarah L French; Martha L Sikes; Robert D Hontz; Yvonne N Osheim; Tashima E Lambert; Aziz El Hage; Mitchell M Smith; David Tollervey; Jeffrey S Smith; Ann L Beyer
Distinguishing the roles of Topoisomerases I and II in relief of transcription-induced torsional stress in yeast rRNA genes.
Mingguang Li; Brian J Petteys; Julie M McClure; Veena Valsakumar; Stefan Bekiranov; Elizabeth L Frank; Jeffrey S Smith
Thiamine biosynthesis in Saccharomyces cerevisiae is regulated by the NAD+-dependent histone deacetylase Hst1.

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All Publications

2012: Julie M McClure; Nazif Maqani; Margaret B Wierman; Jeffrey S Smith
Isonicotinamide enhances Sir2 protein-mediated silencing and longevity in yeast by raising intracellular NAD+ concentration.
The Journal of biological chemistry 2012;287(25):20957-66.
2011: Sarah L French; Martha L Sikes; Robert D Hontz; Yvonne N Osheim; Tashima E Lambert; Aziz El Hage; Mitchell M Smith; David Tollervey; Jeffrey S Smith; Ann L Beyer
Distinguishing the roles of Topoisomerases I and II in relief of transcription-induced torsional stress in yeast rRNA genes.
Molecular and cellular biology 2011;31(3):482-94.
2010: Mingguang Li; Brian J Petteys; Julie M McClure; Veena Valsakumar; Stefan Bekiranov; Elizabeth L Frank; Jeffrey S Smith
Thiamine biosynthesis in Saccharomyces cerevisiae is regulated by the NAD+-dependent histone deacetylase Hst1.
Molecular and cellular biology 2010;30(13):3329-41.
2010: Mirela Matecic; Daniel L Smith; Xuewen Pan; Nazif Maqani; Stefan Bekiranov; Jef Boeke; Jeffrey S Smith
A microarray-based genetic screen for yeast chronological aging factors.
PLoS genetics 2010;6(4):e1000921.
2009: Daniel L Smith; Chonghua Li; Mirela Matecic; Nazif Maqani; Mary Bryk; Jeffrey S Smith
Calorie restriction effects on silencing and recombination at the yeast rDNA.
Aging cell 2009;8(6):633-42.
2009: Robert D Hontz; Rachel O Niederer; Joseph M Johnson; Jeffrey S Smith
Genetic identification of factors that modulate ribosomal DNA transcription in Saccharomyces cerevisiae.
Genetics 2009;182(1):105-19.
2008: Robert D Hontz; Sarah L French; Melanie L Oakes; Prasad Tongaonkar; Masayasu Nomura; Ann L Beyer; Jeffrey S Smith
Transcription of multiple yeast ribosomal DNA genes requires targeting of UAF to the promoter by Uaf30.
Molecular and cellular biology 2008;28(21):6709-19.
2008: Julie M McClure; Christopher M Gallo; Daniel L Smith; Mirela Matecic; Robert D Hontz; Stephen W Buck; Frances G Racette; Jeffrey S Smith
Pnc1p-mediated nicotinamide clearance modifies the epigenetic properties of rDNA silencing in Saccharomyces cerevisiae.
Genetics 2008;180(2):797-810.
2007: Daniel L Smith; Julie M McClure; Mirela Matecic; Jeffrey S Smith
Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins.
Aging cell 2007;6(5):649-62.
2007: Arindam Dasgupta; Rebekka O Sprouse; Sarah French; Pavel Aprikian; Robert Hontz; Sarah A Juedes; Jeffrey S Smith; Ann L Beyer; David T Auble
Regulation of rRNA synthesis by TATA-binding protein-associated factor Mot1.
Molecular and cellular biology 2007;27(8):2886-96.
2004: Arindam Dasgupta; Kerrington L Ramsey; Jeffrey S Smith; David T Auble
Sir Antagonist 1 (San1) is a ubiquitin ligase.
The Journal of biological chemistry 2004;279(26):26830-8.
2004: Stephen W Buck; Christopher M Gallo; Jeffrey S Smith
Diversity in the Sir2 family of protein deacetylases.
Journal of leukocyte biology 2004;75(6):939-50.
2004: Christopher M Gallo; Daniel L Smith; Jeffrey S Smith
Nicotinamide clearance by Pnc1 directly regulates Sir2-mediated silencing and longevity.
Molecular and cellular biology 2004;24(3):1301-12.
2002: Stephen W Buck; Joseph J Sandmeier; Jeffrey S Smith
RNA polymerase I propagates unidirectional spreading of rDNA silent chromatin.
Cell 2002;111(7):1003-14.
2002: Joseph J Sandmeier; Sarah French; Yvonne N Osheim; Wang L Cheung; Christopher M Gallo; Ann L Beyer; Jeffrey S Smith
RPD3 is required for the inactivation of yeast ribosomal DNA genes in stationary phase.
The EMBO journal 2002;21(18):4959-68.
2002: Joseph J Sandmeier; Ivana Celic; Jef Boeke; Jeffrey S Smith
Telomeric and rDNA silencing in Saccharomyces cerevisiae are dependent on a nuclear NAD(+) salvage pathway.
Genetics 2002;160(3):877-89.
2002: Jeffrey S Smith; José L Avalos; Ivana Celic; Shabazz Muhammad; Cynthia Wolberger; Jef Boeke
SIR2 family of NAD(+)-dependent protein deacetylases.
Methods in enzymology 2002;353():282-300.
2001: Jeffrey S Smith; Jef Boeke
Transcription. Is S phase important for transcriptional silencing?
Science (New York, N.Y.) 2001;291(5504):608-9.
2000: Jeffrey S Smith; CB Brachmann; Ivana Celic; M A Kenna; Shabazz Muhammad; Vincent Starai; José L Avalos; Jorge C Escalante-Semerena; C Grubmeyer; Cynthia Wolberger; Jef Boeke
A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6658-63.
1999: Jeffrey S Smith; Emerita M Caputo; Jef Boeke
A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors.
Molecular and cellular biology 1999;19(4):3184-97.
1998: Jeffrey S Smith; CB Brachmann; Lorraine Pillus; Jef Boeke
Distribution of a limited Sir2 protein pool regulates the strength of yeast rDNA silencing and is modulated by Sir4p.
Genetics 1998;149(3):1205-19.
1997: Jeffrey S Smith; Jef Boeke
An unusual form of transcriptional silencing in yeast ribosomal DNA.
Genes & development 1997;11(2):241-54.