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Martin Smith

Research Profile

Chemicals & Drugs

Disorders

DNA Damage

Physiology

Living Beings

Mouse

Genes & Molecular Sequences

Genes, p53

Anatomy

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Comet Assay

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Molecular Sequence Data

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Publications

TOP 3
Joshua L Fischer; M A Suresh Kumar; Travis W Day; Tabitha M Hardy; Shari Hamilton; Cynthia Besch-Williford; Ahmad R Safa; Karen E Pollok; Martin L Smith
The Xpc gene markedly affects cell survival in mouse bone marrow.
Hwa Jin Jung; E H Kim; J-Y Mun; S Park; Martin L Smith; S S Han; Young Rok Seo
Base excision DNA repair defect in Gadd45a-deficient cells.
Joshua L Fischer; Elaine M Mihelc; Karen E Pollok; Martin L Smith
Chemotherapeutic selectivity conferred by selenium: a role for p53-dependent DNA repair.

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All Publications

2009: Joshua L Fischer; M A Suresh Kumar; Travis W Day; Tabitha M Hardy; Shari Hamilton; Cynthia Besch-Williford; Ahmad R Safa; Karen E Pollok; Martin L Smith
The Xpc gene markedly affects cell survival in mouse bone marrow.
Mutagenesis 2009;24(4):309-16.
2007: Hwa Jin Jung; E H Kim; J-Y Mun; S Park; Martin L Smith; S S Han; Young Rok Seo
Base excision DNA repair defect in Gadd45a-deficient cells.
Oncogene 2007;26(54):7517-25.
2007: Joshua L Fischer; Elaine M Mihelc; Karen E Pollok; Martin L Smith
Chemotherapeutic selectivity conferred by selenium: a role for p53-dependent DNA repair.
Molecular cancer therapeutics 2007;6(1):355-61.
2007: Melissa L Fishel; Ying He; Martin L Smith; Mark R Kelley
Manipulation of base excision repair to sensitize ovarian cancer cells to alkylating agent temozolomide.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(1):260-7.
2006: Joshua L Fischer; Jody K Lancia; Anita Mathur; Martin L Smith
Selenium protection from DNA damage involves a Ref1/p53/Brca1 protein complex.
Anticancer research 2006;26(2A):899-904.
2005: Lindsey D Mayo; Young Rok Seo; Mark Jackson; Martin L Smith; Javier Rivera Guzman; Chandrashekhar K Korgaonkar; David B Donner
Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified.
The Journal of biological chemistry 2005;280(28):25953-9.
2005: Marc S Mendonca; Brendan M Mayhugh; Berry McDowell; Helen Chin-Sinex; Martin L Smith; Joseph R Dynlacht; Dan F Spandau; Davina A Lewis
A radiation-induced acute apoptosis involving TP53 and BAX precedes the delayed apoptosis and neoplastic transformation of CGL1 human hybrid cells.
Radiation research 2005;163(6):614-22.
2005: Jaime M Ranieri; Jeffrey D Wagner; Eric A Wiebke; Rafael Azuaje; Martin L Smith; Stacie Wenck; Joanne Daggy; John J Coleman
Lack of prognostic importance of reverse-transcriptase polymerase chain reaction detection of circulating messenger RNA in patients with melanoma.
Plastic and reconstructive surgery 2005;115(4):1058-63.
2004: Martin L Smith; Jody K Lancia; Timothy I Mercer; C Ip
Selenium compounds regulate p53 by common and distinctive mechanisms.
Anticancer research 2004;24(3a):1401-8.
2003: Melissa L Fishel; Young R Seo; Martin L Smith; Mark R Kelley
Imbalancing the DNA base excision repair pathway in the mitochondria; targeting and overexpressing N-methylpurine DNA glycosylase in mitochondria leads to enhanced cell killing.
Cancer research 2003;63(3):608-15.
2002: Young R Seo; Mark R Kelley; Martin L Smith
Selenomethionine regulation of p53 by a ref1-dependent redox mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(22):14548-53.
2002: Young R Seo; Christopher Sweeney; Martin L Smith
Selenomethionine induction of DNA repair response in human fibroblasts.
Oncogene 2002;21(23):3663-9.
2002: Young R Seo; Edmund I-T Chen; Martin L Smith
Sensitivity of p53-deficient cells to oxaliplatin and thio-TEPA (N, N', N" triethylenethiophosphoramide).
Breast cancer research and treatment 2002;72(3):255-63.
2002: Martin L Smith; Young R Seo
p53 regulation of DNA excision repair pathways.
Mutagenesis 2002;17(2):149-56.
2002: Young R Seo; Melissa L Fishel; Sally A Amundson; Mark R Kelley; Martin L Smith
Implication of p53 in base excision DNA repair: in vivo evidence.
Oncogene 2002;21(5):731-7.
2002: Martin L Smith; Albert J Fornace
Chemotherapeutic targeting of p53.
Cancer biology & therapy 2002;1(1):56-7.
2001: Jae-Chun Ryu; Young Rok Seo; Martin L Smith; Sung Sik Han
The effect of methyl methanesulfonate (MMS)-induced excision repair on p53-dependent apoptosis in human lymphoid cells.
Research communications in molecular pathology and pharmacology 2001;109(1-2):35-51.
2000: Martin L Smith; Young R Seo
Sensitivity of cyclin E-overexpressing cells to cisplatin/taxol combinations.
Anticancer research 2000;20(4):2537-9.
1999: Martin L Smith
Mdm2 sensitizes MCF7 breast cancer cells to cisplatin or carboplatin.
Breast cancer research and treatment 1999;58(2):99-105.
1999: Dai-Wu Seol; Q Chen; Martin L Smith; Rasa Zarnegar
Regulation of the c-met proto-oncogene promoter by p53.
The Journal of biological chemistry 1999;274(6):3565-72.
1999: Young Rok Seo; Martin L Smith; Sung Sik Han; DW Fairbairn; Kim L O'Neill; Jae-Chun Ryu
Mild hyperthermia-induced apoptosis is dependent on p53 in human lymphoid cells.
Research communications in molecular pathology and pharmacology 1999;104(3):285-92.
1997: Martin L Smith; A J Fornace
Correspondence re: J. S. DeFrank et al., p53-null cells are more sensitive to ultraviolet light only in the presence of caffeine. Cancer Res., 56: 5365-5368, 1996.
Cancer research 1997;57(23):5434-6.
1997: Martin L Smith; Albert J Fornace
p53-mediated protective responses to UV irradiation.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(23):12255-7.
1996: Martin L Smith; A J Fornace
The two faces of tumor suppressor p53.
The American journal of pathology 1996;148(4):1019-22.
1995: Katherine E Kilpatrick; France Carrier; Martin L Smith; C Y Chen; A J Lee; D W Rusnak; Michael B Kastan; A J Fornace; BR Champion; Tona M Gilmer
The production and characterization of murine monoclonal antibodies to human Gadd45 raised against a recombinant protein.
Hybridoma 1995;14(4):355-9.
1995: Martin L Smith; A J Fornace
Genomic instability and the role of p53 mutations in cancer cells.
Current opinion in oncology 1995;7(1):69-75.
1993: Xiaoying Yin; Martin L Smith; Theresa L Whiteside; Jonas T Johnson; Ronald Herberman; Joseph Locker
Abnormalities in the p53 gene in tumors and cell lines of human squamous-cell carcinomas of the head and neck.
International journal of cancer. Journal international du cancer 1993;54(2):322-7.
1993: Martin L Smith; L Yeleswarapu; P Scalamogna; Joseph Locker; B Lombardi
p53 mutations in hepatocellular carcinomas induced by a choline-devoid diet in male Fischer 344 rats.
Carcinogenesis 1993;14(3):503-10.
1993: Martin L Smith; L Yeleswarapu; B Lombardi; Hisashi Shinozuka
Lack of mutations of the p53 tumor suppressor gene in hepatocellular carcinomas induced in rats by a peroxisome proliferator.
Molecular carcinogenesis 1993;7(2):89-93.
1993: Martin L Smith; N Chandar; B Lombardi
Low frequency of retinoblastoma gene alterations in rat hepatocellular carcinomas.
Molecular carcinogenesis 1993;8(4):228-33.
1991: Martin L Smith; L Yeleswarapu; Joseph Locker; B Lombardi
Expression of p53 mutant protein(s) in diethylnitrosamine-induced foci of enzyme-altered hepatocytes in male Fischer-344 rats.
Carcinogenesis 1991;12(6):1137-41.
1990: Martin L Smith; P J Mitchell; G F Crouse
Analysis of the mouse Dhfr/Rep-3 major promoter region by using linker-scanning and internal deletion mutations and DNase I footprinting.
Molecular and cellular biology 1990;10(11):6003-12.
1989: Martin L Smith; G F Crouse
Construction of linker-scanning mutations using a kanamycin-resistance cassette with multiple symmetric restriction sites.
Gene 1989;84(1):159-64.
1988: G F Crouse; L A Stivaletta; Martin L Smith
Analysis of gene expression using episomal mouse dihydrofolate reductase minigenes.
Nucleic acids research 1988;16(14B):7025-42.