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Martyn Smith

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Luoping Zhang; Bryan A Bassig; John D Curry; Yichen Ge; Weihong Guo; Wei Hu; Hanlin Huang; Zhiying Ji; Laiyu Li; Songwang Liu; Cliona M McHale; Joseph L Mora; Mark P Purdue; Chuangyi Qiu; Boris Reiss; Nathaniel Rothman; Min Shen; Martyn T Smith; Xiaojiang Tang; Roel Vermeulen; Fei Yue; Qing Lan
Alterations in serum immunoglobulin levels in workers occupationally exposed to trichloroethylene.
H Dean Hosgood; Ming Hua; Hanlin Huang; Zhiying Ji; Mariko Azuma; Aaron Blair; Laura Beane Freeman; Noe Galvan; Yichen Ge; Weihong Guo; Zhenyue Hao; Laiyu Li; Senhua Li; Songwang Liu; Chuangyi Qiu; Boris Reiss; Nathaniel Rothman; Xiaolin Ruan; Min Shen; Martyn T Smith; Xiaojiang Tang; Roel Vermeulen; Yuxuan Xie; Kerry X Xin; Jun Xiong; Luoping Zhang; Qing Lan
Occupational exposure to formaldehyde and alterations in lymphocyte subsets.
T Kevin Howcroft; Martyn T Smith; Bradley Wise; Tony Wyss-Coray; Alison Deckhut Augustine; Judith Campisi; Ron Kohanski; Germaine Buck Louis; Janet E McElhaney; Felipe Sierra
The role of inflammation in age-related disease.

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2013: Luoping Zhang; Bryan A Bassig; John D Curry; Yichen Ge; Weihong Guo; Wei Hu; Hanlin Huang; Zhiying Ji; Laiyu Li; Songwang Liu; Cliona M McHale; Joseph L Mora; Mark P Purdue; Chuangyi Qiu; Boris Reiss; Nathaniel Rothman; Min Shen; Martyn T Smith; Xiaojiang Tang; Roel Vermeulen; Fei Yue; Qing Lan
Alterations in serum immunoglobulin levels in workers occupationally exposed to trichloroethylene.
Carcinogenesis 2013;34(4):799-802.
2013: H Dean Hosgood; Ming Hua; Hanlin Huang; Zhiying Ji; Mariko Azuma; Aaron Blair; Laura Beane Freeman; Noe Galvan; Yichen Ge; Weihong Guo; Zhenyue Hao; Laiyu Li; Senhua Li; Songwang Liu; Chuangyi Qiu; Boris Reiss; Nathaniel Rothman; Xiaolin Ruan; Min Shen; Martyn T Smith; Xiaojiang Tang; Roel Vermeulen; Yuxuan Xie; Kerry X Xin; Jun Xiong; Luoping Zhang; Qing Lan
Occupational exposure to formaldehyde and alterations in lymphocyte subsets.
American journal of industrial medicine 2013;56(2):252-7.
2013: T Kevin Howcroft; Martyn T Smith; Bradley Wise; Tony Wyss-Coray; Alison Deckhut Augustine; Judith Campisi; Ron Kohanski; Germaine Buck Louis; Janet E McElhaney; Felipe Sierra
The role of inflammation in age-related disease.
Aging 2013;5(1):84-93.
2013: Xuefeng Ren; Martyn T Smith; Maycky Tang; Jessica Yuh; Jessica Bersonda; Zhiying Ji; Cliona M McHale; Luoping Zhang
The impact of FANCD2 deficiency on formaldehyde-induced toxicity in human lymphoblastoid cell lines.
Archives of toxicology 2013;87(1):189-96.
2012: Luoping Zhang; M Shen; Martyn T Smith; Roel Vermeulen; Songnian Yin; W Guo; Richard Hayes; Alan E Hubbard; Z Ji; Qing Lan; Guilan Li; M S Linet; Cliona M McHale; Stephen M Rappaport; Nathaniel Rothman
Leukemia-related chromosomal loss detected in hematopoietic progenitor cells of benzene-exposed workers.
Leukemia 2012;26(12):2494-8.
2012: Michele Fromowitz; Zhiying Ji; Matthew North; Joe Shuga; Martyn T Smith; Chris D Vulpe; Antonio Yip Wlassowsky; Luoping Zhang
Bone marrow genotoxicity of 2,5-dimethylfuran, a green biofuel candidate.
Environmental and molecular mutagenesis 2012;53(6):488-91.
2012: Christine F Skibola; Martyn T Smith; Elizabeth Trachtenberg; N K Akers; F Cohen; L Conde; Henry A Erlich; D Goodridge; S K Hawbecker; M Ladner; F Ribas; Paige M Bracci
Multi-locus HLA class I and II allele and haplotype associations with follicular lymphoma.
Tissue antigens 2012;79(4):279-86.
2012: Cliona M McHale; Luoping Zhang; Martyn T Smith
Current understanding of the mechanism of benzene-induced leukemia in humans: implications for risk assessment.
Carcinogenesis 2012;33(2):240-52.
2012: Sean Timothy Francis O'Connor; Martyn T Smith; Luoping Zhang; April Z Gu; Jiaqi Lan; Alex Loguinov; Matthew North; Christopher D Vulpe
Genome-Wide Functional and Stress Response Profiling Reveals Toxic Mechanism and Genes Required for Tolerance to Benzo[a]pyrene in S. cerevisiae.
Frontiers in genetics 2012;3():316.
2011: N K Akers; Paige M Bracci; John D Curry; Martyn T Smith; Christine F Skibola
Multiplexed, ligation-dependent probe amplification for rapid and inexpensive HLA-DQB1 allelotyping.
Tissue antigens 2011;78(4):275-80.
2011: Min Shen; Martyn T Smith; Roel Vermeulen; Songnian Yin; Luoping Zhang; STEPHEN CHANOCK; H Dean Hosgood; Kyoung-Mu Lee; Guilan Li; Nathaniel Rothman; Qing Lan
Polymorphisms in genes involved in innate immunity and susceptibility to benzene-induced hematotoxicity.
Experimental & molecular medicine 2011;43(6):374-8.
2011: Martyn T Smith; Luoping Zhang; Cliona M McHale; Christine F Skibola; Stephen M Rappaport
Benzene, the exposome and future investigations of leukemia etiology.
Chemico-biological interactions 2011;192(1-2):155-9.
2011: Xuefeng Ren; Maria Aleshin; William J Jo; Russel Dills; David A Kalman; Christopher D Vulpe; Martyn T Smith; Luoping Zhang
Involvement of N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) in arsenic biomethylation and its role in arsenic-induced toxicity.
Environmental health perspectives 2011;119(6):771-7.
2011: Cliona M McHale; Luoping Zhang; Qing Lan; Roel Vermeulen; Guilan Li; Alan E Hubbard; Kristin E Porter; Reuben Thomas; Christopher J Portier; Min Shen; Stephen M Rappaport; Songnian Yin; Martyn T Smith; Nathaniel Rothman
Global gene expression profiling of a population exposed to a range of benzene levels.
Environmental health perspectives 2011;119(5):628-34.
2011: Luoping Zhang; Qing Lan; Weihong Guo; Alan E Hubbard; Guilan Li; Stephen M Rappaport; Cliona M McHale; Min Shen; Zhiying Ji; Roel Vermeulen; Songnian Yin; Nathaniel Rothman; Martyn T Smith
Chromosome-wide aneuploidy study (CWAS) in workers exposed to an established leukemogen, benzene.
Carcinogenesis 2011;32(4):605-12.
2011: Richard Novak; Yong Zeng; Joe Shuga; Gautham Venugopalan; Daniel A Fletcher; Martyn T Smith; Richard A Mathies
Single-cell multiplex gene detection and sequencing with microfluidically generated agarose emulsions.
Angewandte Chemie (International ed. in English) 2011;50(2):390-5.
2011: Martyn T Smith; Paul A Schulte; Paolo Boffetta; STEPHEN CHANOCK; Pierre Hainaut; Frederica Perera; Nathaniel Rothman
Future perspectives on molecular epidemiology.
IARC scientific publications 2011;(163):493-500.
2011: Joe Shuga; Pierre Hainaut; Martyn T Smith
Assessment of genetic damage in healthy and diseased tissue.
IARC scientific publications 2011;(163):63-97.
2011: H Dean Hosgood; Hanlin Huang; Zhiying Ji; Noe Galvan; Yichen Ge; Weihong Guo; Zhenyue Hao; Jian He; Laiyu Li; Songwang Liu; Chuangyi Qiu; Boris Reiss; Nathaniel Rothman; Min Shen; Martyn T Smith; Xiaojiang Tang; Roel Vermeulen; Yuxuan Xie; Jun Xiong; Luoping Zhang; Qing Lan
Decreased Numbers of CD4(+) Naive and Effector Memory T Cells, and CD8(+) Naïve T Cells, are Associated with Trichloroethylene Exposure.
Frontiers in oncology 2011;1():53.
2011: Matthew North; Martyn T Smith; Vickram J Tandon; Reuben Thomas; Inna Gerlovina; Alan E Hubbard; Alex Loguinov; Luoping Zhang; Christopher D Vulpe
Genome-wide functional profiling reveals genes required for tolerance to benzene metabolites in yeast.
PloS one 2011;6(8):e24205.
2011: Xuefeng Ren; Sophia Lim; Zhiying Ji; Jessica Yuh; Vivian Peng; Martyn T Smith; Luoping Zhang
Comparison of proliferation and genomic instability responses to WRN silencing in hematopoietic HL60 and TK6 cells.
PloS one 2011;6(1):e14546.
2011: Nicholas K Akers; John D Curry; Lucia Conde; Paige M Bracci; Martyn T Smith; Christine F Skibola
Association of HLA-DQB1 alleles with risk of follicular lymphoma.
Leukemia & lymphoma 2011;52(1):53-8.
2011: Craig Steinmaus; Allan H Smith; Martyn T Smith
Regarding "meta-analysis and causal inference: a case study of benzene and non-Hodgkin lymphoma": an incomplete analysis.
Annals of epidemiology 2011;21(1):67-9; author reply 70-1.
2011: Xuefeng Ren; Cliona M McHale; Christine F Skibola; Allan H Smith; Martyn T Smith; Luoping Zhang
An emerging role for epigenetic dysregulation in arsenic toxicity and carcinogenesis.
Environmental health perspectives 2011;119(1):11-9.
2010: Cliona M McHale; Luoping Zhang; Alan E Hubbard; Martyn T Smith
Toxicogenomic profiling of chemically exposed humans in risk assessment.
Mutation research 2010;705(3):172-83.
2010: Stephen M Rappaport; Martyn T Smith
Epidemiology. Environment and disease risks.
Science (New York, N.Y.) 2010;330(6003):460-1.
2010: Joseph L Wiemels; Michelle Kang; Jeffrey S Chang; Lily Zheng; Carina Kouyoumji; Luoping Zhang; Martyn T Smith; Ghislaine Scelo; Catherine Metayer; Patricia A Buffler; John K Wiencke
Backtracking RAS mutations in high hyperdiploid childhood acute lymphoblastic leukemia.
Blood cells, molecules & diseases 2010;45(3):186-91.
2010: Joe Shuga; Yong Zeng; Richard Novak; Richard A Mathies; Pierre Hainaut; Martyn T Smith
Selected technologies for measuring acquired genetic damage in humans.
Environmental and molecular mutagenesis 2010;51(8-9):851-70.
2010: Qing Lan; Luoping Zhang; Xiaojiang Tang; Min Shen; Martyn T Smith; Chuangyi Qiu; Yichen Ge; Zhiying Ji; Jun Xiong; Jian He; Boris Reiss; Zhenyue Hao; Songwang Liu; Yuxuan Xie; Weihong Guo; Mark P Purdue; Noe Galvan; Kerry X Xin; Wei Hu; Laura E Beane Freeman; Aaron E Blair; Laiyu Li; Nathaniel Rothman; Roel Vermeulen; Hanlin Huang
Occupational exposure to trichloroethylene is associated with a decline in lymphocyte subsets and soluble CD27 and CD30 markers.
Carcinogenesis 2010;31(9):1592-6.
2010: Kristin E Porter; Anamika Basu; Alan E Hubbard; Michael N Bates; David Kalman; Omar A Rey; Allan Smith; Martyn T Smith; Craig Steinmaus; Christine F Skibola
Association of genetic variation in cystathionine-beta-synthase and arsenic metabolism.
Environmental research 2010;110(6):580-7.
2010: Tracy Lightfoot; Eve Roman; Martyn T Smith; Christine F Skibola
Acute lymphoblastic leukaemia in children - is there a role for MTHFR?
British journal of haematology 2010;149(5):797-8; author reply 799-800.
2010: Tracy Lightfoot; W Thomas Johnston; Dan Painter; Jill Simpson; Eve Roman; Christine F Skibola; Martyn T Smith; James M Allan; G Malcolm Taylor
Genetic variation in the folate metabolic pathway and risk of childhood leukemia.
Blood 2010;115(19):3923-9.
2010: Z Ji; Luoping Zhang; V Peng; X Ren; Cliona M McHale; Martyn T Smith
A comparison of the cytogenetic alterations and global DNA hypomethylation induced by the benzene metabolite, hydroquinone, with those induced by melphalan and etoposide.
Leukemia 2010;24(5):986-91.
2010: Yong Zeng; Richard Novak; Joe Shuga; Martyn T Smith; Richard A Mathies
High-performance single cell genetic analysis using microfluidic emulsion generator arrays.
Analytical chemistry 2010;82(8):3183-90.
2010: Luoping Zhang; Laura E Beane Freeman; Jun Nakamura; Stephen S Hecht; John J Vandenberg; Martyn T Smith; Babasaheb R Sonawane
Formaldehyde and leukemia: epidemiology, potential mechanisms, and implications for risk assessment.
Environmental and molecular mutagenesis 2010;51(3):181-91.
2010: Stephen M Rappaport; Sungkyoon Kim; Qing Lan; Guilan Li; Roel Vermeulen; Suramya Waidyanatha; Luoping Zhang; Songnian Yin; Martyn T Smith; Nathaniel Rothman
Human benzene metabolism following occupational and environmental exposures.
Chemico-biological interactions 2010;184(1-2):189-95.
2010: Luoping Zhang; Cliona M McHale; Nathaniel Rothman; Guilan Li; Zhiying Ji; Roel Vermeulen; Alan E Hubbard; Xuefeng Ren; Min Shen; Stephen M Rappaport; Matthew North; Christine F Skibola; Songnian Yin; Christopher Vulpe; STEPHEN CHANOCK; Martyn T Smith; Qing Lan
Systems biology of human benzene exposure.
Chemico-biological interactions 2010;184(1-2):86-93.
2010: Martyn T Smith
Advances in understanding benzene health effects and susceptibility.
Annual review of public health 2010;31():133-48 2 p following 148.
2009: Xiaojiang Tang; Yang Bai; Anh Duong; Martyn T Smith; Laiyu Li; Luoping Zhang
Formaldehyde in China: production, consumption, exposure levels, and health effects.
Environment international 2009;35(8):1210-24.
2009: Christine F Skibola; Paige M Bracci; Eran Halperin; Lucia Conde; David Craig; Luz Agana; Kelly Iyadurai; Nikolaus Becker; Angela Brooks-Wilson; John D Curry; John Spinelli; Elizabeth A Holly; Jacques Riby; Luoping Zhang; Alexandra Nieters; Martyn T Smith; Kevin Brown
Genetic variants at 6p21.33 are associated with susceptibility to follicular lymphoma.
Nature genetics 2009;41(8):873-5.
2009: Zhiying Ji; Luoping Zhang; Weihong Guo; Cliona M McHale; Martyn T Smith
The benzene metabolite, hydroquinone and etoposide both induce endoreduplication in human lymphoblastoid TK6 cells.
Mutagenesis 2009;24(4):367-72.
2009: Stephen M Rappaport; Sungkyoon Kim; Qing Lan; Roel Vermeulen; Suramya Waidyanatha; Luoping Zhang; Guilan Li; Songnian Yin; Richard B Hayes; Nathaniel Rothman; Martyn T Smith
Evidence that humans metabolize benzene via two pathways.
Environmental health perspectives 2009;117(6):946-52.
2009: Cliona M McHale; Luoping Zhang; Qing Lan; Guilan Li; Alan E Hubbard; Matthew Forrest; Roel Vermeulen; Jinsong Chen; Min Shen; Stephen M Rappaport; Songnian Yin; Martyn T Smith; Nathaniel Rothman
Changes in the peripheral blood transcriptome associated with occupational benzene exposure identified by cross-comparison on two microarray platforms.
Genomics 2009;93(4):343-9.
2009: Luoping Zhang; Craig Steinmaus; David A Eastmond; Xianjun K Xin; Martyn T Smith
Formaldehyde exposure and leukemia: a new meta-analysis and potential mechanisms.
Mutation research 2009;681(2-3):150-68.
2009: Xuefeng Ren; Sophia Lim; Martyn T Smith; Luoping Zhang
Werner syndrome protein, WRN, protects cells from DNA damage induced by the benzene metabolite hydroquinone.
Toxicological sciences : an official journal of the Society of Toxicology 2009;107(2):367-75.
2009: Ghislaine Scélo; Catherine Metayer; Luoping Zhang; Joseph L Wiemels; Melinda C Aldrich; Steve Selvin; Stacy Month; Martyn T Smith; Patricia A Buffler
Household exposure to paint and petroleum solvents, chromosomal translocations, and the risk of childhood leukemia.
Environmental health perspectives 2009;117(1):133-9.
2009: Qing Lan; Luoping Zhang; Min Shen; William J Jo; Roel Vermeulen; Guilan Li; Christopher Vulpe; Sophia Lim; Xuefeng Ren; Stephen M Rappaport; Sonja I Berndt; Meredith Yeager; Jeff Yuenger; Richard Hayes; Martha Linet; Songnian Yin; STEPHEN CHANOCK; Martyn T Smith; Nathaniel Rothman
Large-scale evaluation of candidate genes identifies associations between DNA repair and genomic maintenance and development of benzene hematotoxicity.
Carcinogenesis 2009;30(1):50-8.
2008: Joseph L Wiemels; Jerry Hofmann; Michelle Kang; Rebecca Selzer; Roland Green; Mi Zhou; Sheng Zhong; Luoping Zhang; Martyn T Smith; Carmen Marsit; Mignon L Loh; Patricia A Buffler; Ru-Fang Yeh
Chromosome 12p deletions in TEL-AML1 childhood acute lymphoblastic leukemia are associated with retrotransposon elements and occur postnatally.
Cancer research 2008;68(23):9935-44.
2008: Christine M Hegedus; Christine F Skibola; Marcella Warner; Danica R Skibola; David Alexander; Sophia Lim; Nygerma L Dangleben; Luoping Zhang; Michael Clark; Ruth M Pfeiffer; Craig Steinmaus; Allan H Smith; Martyn T Smith; Lee E Moore
Decreased urinary beta-defensin-1 expression as a biomarker of response to arsenic.
Toxicological sciences : an official journal of the Society of Toxicology 2008;106(1):74-82.
2008: Craig Steinmaus; Allan H Smith; Rachael Jones ; Martyn T Smith
Meta-analysis of benzene exposure and non-Hodgkin lymphoma: biases could mask an important association.
Occupational and environmental medicine 2008;65(6):371-8.
2008: Christine F Skibola; Alexandra Nieters; Paige M Bracci; John D Curry; Luz Agana; Danica R Skibola; Alan Hubbard; Nikolaus Becker; Martyn T Smith; Elizabeth A Holly
A functional TNFRSF5 gene variant is associated with risk of lymphoma.
Blood 2008;111(8):4348-54.
2008: Martyn T Smith
Misuse of genomics in assigning causation in relation to benzene exposure.
International journal of occupational and environmental health 2008;14(2):144-6.
2008: Noé Galván; Sophia Lim; Stephan Zmugg; Martyn T Smith; Luoping Zhang
Depletion of WRN enhances DNA damage in HeLa cells exposed to the benzene metabolite, hydroquinone.
Mutation research 2008;649(1-2):54-61.
2008: Cliona M McHale; Qing Lan; Chiara Corso; Guilan Li; Luoping Zhang; Roel Vermeulen; John D Curry; Min Shen; Rustam Turakulov; Russell Higuchi; Soren Germer; Songnian Yin; Nathaniel Rothman; Martyn T Smith
Chromosome translocations in workers exposed to benzene.
Journal of the National Cancer Institute. Monographs 2008;(39):74-7.
2008: Christine F Skibola; Paige M Bracci; Eran Halperin; Alexandra Nieters; Alan Hubbard; Randi A Paynter; Danica R Skibola; Luz Agana; Nikolaus Becker; Patrick Tressler; Matthew Forrest; Sriram Sankararaman; Lucia Conde; Elizabeth A Holly; Martyn T Smith
Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma.
PloS one 2008;3(7):e2816.
2007: Patricia A Escobar; Martyn T Smith; Ananth Vasishta; Alan E Hubbard; Luoping Zhang
Leukaemia-specific chromosome damage detected by comet with fluorescence in situ hybridization (comet-FISH).
Mutagenesis 2007;22(5):321-7.
2007: Luoping Zhang; Nathaniel Rothman; Guilan Li; Weihong Guo; Wei Yang; Alan E Hubbard; Richard Hayes; Songnian Yin; Wei Lu; Martyn T Smith
Aberrations in chromosomes associated with lymphoma and therapy-related leukemia in benzene-exposed workers.
Environmental and molecular mutagenesis 2007;48(6):467-74.
2007: Martyn T Smith; Rachael Jones ; Allan H Smith
Benzene exposure and risk of non-Hodgkin lymphoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(3):385-91.
2007: Christine M Hegedus; Christine F Skibola; Paige M Bracci; Elizabeth A Holly; Martyn T Smith
Screening the human serum proteome for genotype-phenotype associations: an analysis of the IL6 -174G>C polymorphism.
Proteomics 2007;7(4):548-57.
2007: Sara Rollinson; Alexandra Smith; James M Allan; Peter J Adamson; Kathryn Scott; Christine F Skibola; Martyn T Smith; Gareth J Morgan
RAD51 homologous recombination repair gene haplotypes and risk of acute myeloid leukaemia.
Leukemia research 2007;31(2):169-74.
2007: Cliona M McHale; Luoping Zhang; Alan E Hubbard; Xin Zhao; Andrea Baccarelli; Angela C Pesatori; Martyn T Smith; Maria Teresa Landi
Microarray analysis of gene expression in peripheral blood mononuclear cells from dioxin-exposed human subjects.
Toxicology 2007;229(1-2):101-13.
2006: Randi A Paynter; Danica R Skibola; Christine F Skibola; Patricia A Buffler; Joseph L Wiemels; Martyn T Smith
Accuracy of multiplexed Illumina platform-based single-nucleotide polymorphism genotyping compared between genomic and whole genome amplified DNA collected from multiple sources.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(12):2533-6.
2006: Roel Vermeulen; Qing Lan; Guilan Li; Stephen M Rappaport; Sungkyoon Kim; Berna Van-Wendel-de-Joode; Min Shen; Xu Bohong; Martyn T Smith; Luoping Zhang; Songnian Yin; Nathaniel Rothman
Assessment of dermal exposure to benzene and toluene in shoe manufacturing by activated carbon cloth patches.
Journal of environmental monitoring : JEM 2006;8(11):1143-8.
2006: Andrew J Olaharski; Zhiying Ji; Ji-Young Woo; Sophia Lim; Alan E Hubbard; Luoping Zhang; Martyn T Smith
The histone deacetylase inhibitor trichostatin a has genotoxic effects in human lymphoblasts in vitro.
Toxicological sciences : an official journal of the Society of Toxicology 2006;93(2):341-7.
2006: Min Shen; Qing Lan; Luoping Zhang; STEPHEN CHANOCK; Guilan Li; Roel Vermeulen; Stephen M Rappaport; Weihong Guo; Richard Hayes; Martha Linet; Songnian Yin; Meredith Yeager; Robert Welch; Matthew Forrest; Nathaniel Rothman; Martyn T Smith
Polymorphisms in genes involved in DNA double-strand break repair pathway and susceptibility to benzene-induced hematotoxicity.
Carcinogenesis 2006;27(10):2083-9.
2006: Tracy Lightfoot; Christine F Skibola; Alexandra Smith; Matthew Forrest; Peter J Adamson; Gareth J Morgan; Paige M Bracci; Eve Roman; Martyn T Smith; Elizabeth A Holly
Polymorphisms in the oxidative stress genes, superoxide dismutase, glutathione peroxidase and catalase and risk of non-Hodgkin's lymphoma.
Haematologica 2006;91(9):1222-7.
2006: Matthew Forrest; Christine F Skibola; Tracy Lightfoot; Paige M Bracci; Eleanor V Willett; Martyn T Smith; Elizabeth A Holly; Eve Roman
Polymorphisms in innate immunity genes and risk of non-Hodgkin lymphoma.
British journal of haematology 2006;134(2):180-3.
2006: Melinda C Aldrich; Luoping Zhang; Joseph L Wiemels; Xiaomei Ma; Mignon L Loh; Catherine Metayer; Steve Selvin; James Feusner; Martyn T Smith; Patricia A Buffler
Cytogenetics of Hispanic and White children with acute lymphoblastic leukemia in California.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(3):578-81.
2006: Merrill D Birkner; Alan E Hubbard; Mark J van der Laan; Christine F Skibola; Christine M Hegedus; Martyn T Smith
Issues of processing and multiple testing of SELDI-TOF MS proteomic data.
Statistical applications in genetics and molecular biology 2006;5():Article11.
2005: Tracy Lightfoot; Christine F Skibola; Eleanor V Willett; Danica R Skibola; James M Allan; Fabio Coppede; Peter J Adamson; Gareth J Morgan; Eve Roman; Martyn T Smith
Risk of non-Hodgkin lymphoma associated with polymorphisms in folate-metabolizing genes.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(12):2999-3003.
2005: Andrew J Olaharski; Jasper Rine; Brett L Marshall; Joshua Babiarz; Luoping Zhang; Eric Verdin; Martyn T Smith
The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases.
PLoS genetics 2005;1(6):e77.
2005: Roel Vermeulen; Qing Lan; Luoping Zhang; Laura Gunn; Diane McCarthy; Ronald L Woodbury; Marielena McGuire; Vladimir N Podust; Guilan Li; Nilanjan Chatterjee; Ruidong Mu; Songnian Yin; Nathaniel Rothman; Martyn T Smith
Decreased levels of CXC-chemokines in serum of benzene-exposed workers identified by array-based proteomics.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(47):17041-6.
2005: Qing Lan; Luoping Zhang; Min Shen; Martyn T Smith; Guilan Li; Roel Vermeulen; Stephen M Rappaport; Matthew Forrest; Richard Hayes; Martha Linet; Mustafa Dosemeci; BLANCHE ALTER; Rona S Weinberg; Songnian Yin; Meredith Yeager; Robert Welch; Suramya Waidyanatha; Sungkyoon Kim; STEPHEN CHANOCK; Nathaniel Rothman
Polymorphisms in cytokine and cellular adhesion molecule genes and susceptibility to hematotoxicity among workers exposed to benzene.
Cancer research 2005;65(20):9574-81.
2005: Eleanor V Willett; Christine F Skibola; P Adamson; Danica R Skibola; Gareth J Morgan; Martyn T Smith; Eve Roman
Non-Hodgkin's lymphoma, obesity and energy homeostasis polymorphisms.
British journal of cancer 2005;93(7):811-6.
2005: Christine F Skibola; Paige M Bracci; Randi A Paynter; Matthew Forrest; Luz Agana; Trevor Woodage; Karl J Guegler; Martyn T Smith; Elizabeth A Holly
Polymorphisms and haplotypes in the cytochrome P450 17A1, prolactin, and catechol-O-methyltransferase genes and non-Hodgkin lymphoma risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(10):2391-401.
2005: Christine M Hegedus; Laura Gunn; Christine F Skibola; Luoping Zhang; R Shiao; S Fu; E A Dalmasso; Catherine Metayer; G V Dahl; Patricia A Buffler; Martyn T Smith
Proteomic analysis of childhood leukemia.
Leukemia 2005;19(10):1713-8.
2005: Martyn T Smith; Cliona M McHale; Joseph L Wiemels; Luoping Zhang; John K Wiencke; Shichun Zheng; Laura Gunn; Christine F Skibola; Xiaomei Ma; Patricia A Buffler
Molecular biomarkers for the study of childhood leukemia.
Toxicology and applied pharmacology 2005;206(2):237-45.
2005: Matthew Forrest; Qing Lan; Alan E Hubbard; Luoping Zhang; Roel Vermeulen; Xin Zhao; Guilan Li; Yen-Ying Wu; Min Shen; Songnian Yin; STEPHEN CHANOCK; Nathaniel Rothman; Martyn T Smith
Discovery of novel biomarkers by microarray analysis of peripheral blood mononuclear cell gene expression in benzene-exposed workers.
Environmental health perspectives 2005;113(6):801-7.
2005: Christine F Skibola; Tracy Lightfoot; Luz Agana; Alexandra Smith; Sara Rollinson; Andrew Kao; Peter Adamson; Gareth J Morgan; Martyn T Smith; Eve Roman
Polymorphisms in cytochrome P450 17A1 and risk of non-Hodgkin lymphoma.
British journal of haematology 2005;129(5):618-21.
2005: Martyn T Smith; Roel Vermeulen; Guilan Li; Luoping Zhang; Qing Lan; Alan E Hubbard; Matthew Forrest; Cliona M McHale; Xin Zhao; Laura Gunn; Min Shen; Stephen M Rappaport; Songnian Yin; STEPHEN CHANOCK; Nathaniel Rothman
Use of 'Omic' technologies to study humans exposed to benzene.
Chemico-biological interactions 2005;153-154():123-7.
2005: Luoping Zhang; Qing Lan; Weihong Guo; Guilan Li; Wei Yang; Alan E Hubbard; Roel Vermeulen; Stephen M Rappaport; Songnian Yin; Nathaniel Rothman; Martyn T Smith
Use of OctoChrome fluorescence in situ hybridization to detect specific aneuploidy among all 24 chromosomes in benzene-exposed workers.
Chemico-biological interactions 2005;153-154():117-22.
2005: Qing Lan; Luoping Zhang; Frances T Hakim; Min Shen; Sarfraz A Memon; Guilan Li; Roel Vermeulen; Martyn T Smith; Stephen M Rappaport; Richard Hayes; Martha Linet; Songnian Yin; Nathaniel Rothman; Charles S Rabkin
Lymphocyte toxicity and T cell receptor excision circles in workers exposed to benzene.
Chemico-biological interactions 2005;153-154():111-5.
2005: Danica R Skibola; Martyn T Smith; Paige M Bracci; Alan E Hubbard; Luz Agana; Shawn Chi; Elizabeth A Holly
Polymorphisms in ghrelin and neuropeptide Y genes are associated with non-Hodgkin lymphoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(5):1251-6.
2005: Luoping Zhang; Wei Yang; Alan E Hubbard; Martyn T Smith
Nonrandom aneuploidy of chromosomes 1, 5, 6, 7, 8, 9, 11, 12, and 21 induced by the benzene metabolites hydroquinone and benzenetriol.
Environmental and molecular mutagenesis 2005;45(4):388-96.
2005: Joseph L Wiemels; Y Zhang; J Chang; Shichun Zheng; Catherine Metayer; Luoping Zhang; Martyn T Smith; Xiaomei Ma; Steve Selvin; Patricia A Buffler; John K Wiencke
RAS mutation is associated with hyperdiploidy and parental characteristics in pediatric acute lymphoblastic leukemia.
Leukemia 2005;19(3):415-9.
2005: Christine F Skibola; John D Curry; Catherine A VandeVoort; Alan J Conley; Martyn T Smith
Brown kelp modulates endocrine hormones in female sprague-dawley rats and in human luteinized granulosa cells.
The Journal of nutrition 2005;135(2):296-300.
2005: Lee E Moore; R Pfeiffer; M Warner; M Clark; C Skibola; C Steinmous; Juan Alguacil; Nathaniel Rothman; Martyn T Smith; A H Smith
Identification of biomarkers of arsenic exposure and metabolism in urine using SELDI technology.
Journal of biochemical and molecular toxicology 2005;19(3):176.
2004: Qing Lan; Luoping Zhang; Guilan Li; Roel Vermeulen; Rona S Weinberg; Mustafa Dosemeci; Stephen M Rappaport; Min Shen; BLANCHE ALTER; Yongji Wu; William Kopp; Suramya Waidyanatha; Charles S Rabkin; Weihong Guo; STEPHEN CHANOCK; Richard Hayes; Martha Linet; Sungkyoon Kim; Songnian Yin; Nathaniel Rothman; Martyn T Smith
Hematotoxicity in workers exposed to low levels of benzene.
Science (New York, N.Y.) 2004;306(5702):1774-6.
2004: Christine F Skibola; Matthew Forrest; Fabio Coppedé; Luz Agana; Alan Hubbard; Martyn T Smith; Paige M Bracci; Elizabeth A Holly
Polymorphisms and haplotypes in folate-metabolizing genes and risk of non-Hodgkin lymphoma.
Blood 2004;104(7):2155-62.
2004: Sara Rollinson; James M Allan; Graham Law; Philippa L Roddam; Martyn T Smith; Christine F Skibola; Alexandra Smith; Matthew Forrest; Kathryn Sibley; Russell Higuchi; Søren Germer; Gareth J Morgan
High-throughput association testing on DNA pools to identify genetic variants that confer susceptibility to acute myeloid leukemia.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(5):795-800.
2004: Christine F Skibola; Elizabeth A Holly; Matthew Forrest; Alan Hubbard; Paige M Bracci; Danica R Skibola; Christine M Hegedus; Martyn T Smith
Body mass index, leptin and leptin receptor polymorphisms, and non-hodgkin lymphoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(5):779-86.
2004: Cliona M McHale; Martyn T Smith
Prenatal origin of chromosomal translocations in acute childhood leukemia: implications and future directions.
American journal of hematology 2004;75(4):254-7.
2004: Shichun Zheng; Xiaomei Ma; Luoping Zhang; Laura Gunn; Martyn T Smith; Joseph L Wiemels; Kenneth Leung; Patricia A Buffler; John K Wiencke
Hypermethylation of the 5' CpG island of the FHIT gene is associated with hyperdiploid and translocation-negative subtypes of pediatric leukemia.
Cancer research 2004;64(6):2000-6.
2004: Luoping Zhang; Richard Hayes; Weihong Guo; Cliona M McHale; Songnian Yin; John K Wiencke; J Patrick O'Neill; Nathaniel Rothman; Gui-Lan Li; Martyn T Smith
Lack of increased genetic damage in 1,3-butadiene-exposed Chinese workers studied in relation to EPHX1 and GST genotypes.
Mutation research 2004;558(1-2):63-74.
2004: Roel Vermeulen; Guilan Li; Qing Lan; Mustafa Dosemeci; Stephen M Rappaport; Xu Bohong; Martyn T Smith; Luoping Zhang; Richard Hayes; Martha Linet; Ruidong Mu; Lan Wang; Jianing Xu; Songnian Yin; Nathaniel Rothman
Detailed exposure assessment for a molecular epidemiology study of benzene in two shoe factories in China.
The Annals of occupational hygiene 2004;48(2):105-16.
2004: Laura Gunn; Martyn T Smith
Emerging biomarker technologies.
IARC scientific publications 2004;(157):437-50.
2004: Martyn T Smith; Christine F Skibola; James M Allan; Gareth J Morgan
Causal models of leukaemia and lymphoma.
IARC scientific publications 2004;(157):373-92.
2004: Anneclaire J De Roos; Martyn T Smith; STEPHEN CHANOCK; Nathaniel Rothman
Toxicological considerations in the application and interpretation of susceptibility biomarkers in epidemiological studies.
IARC scientific publications 2004;(157):105-25.
2003: Kathryn Sibley; Sara Rollinson; James M Allan; Alexandra Smith; Graham Law; Philippa L Roddam; Christine F Skibola; Martyn T Smith; Gareth J Morgan
Functional FAS promoter polymorphisms are associated with increased risk of acute myeloid leukemia.
Cancer research 2003;63(15):4327-30.
2003: John D Curry; Martyn T Smith
Measurement of SIL-TAL1 fusion gene transcripts associated with human T-cell lymphocytic leukemia by real-time reverse transcriptase-PCR.
Leukemia research 2003;27(7):575-82.
2003: Martyn T Smith
Mechanisms of troglitazone hepatotoxicity.
Chemical research in toxicology 2003;16(6):679-87.
2003: Nina T Holland; Martyn T Smith; Brenda Eskenazi; Maria Bastaki
Biological sample collection and processing for molecular epidemiological studies.
Mutation research 2003;543(3):217-34.
2003: Cliona M McHale; Joseph L Wiemels; Luoping Zhang; Xiaomei Ma; Patricia A Buffler; James Feusner; Katherine Matthay; Gary Dahl; Martyn T Smith
Prenatal origin of childhood acute myeloid leukemias harboring chromosomal rearrangements t(15;17) and inv(16).
Blood 2003;101(11):4640-1.
2003: Cliona M McHale; Joseph L Wiemels; Luoping Zhang; Xiaomei Ma; Patricia A Buffler; Weihong Guo; Mignon L Loh; Martyn T Smith
Prenatal origin of TEL-AML1-positive acute lymphoblastic leukemia in children born in California.
Genes, chromosomes & cancer 2003;37(1):36-43.
2003: David T Bowen; Marion E Frew; Sara Rollinson; Philippa L Roddam; Ann M Dring; Martyn T Smith; Stephen E Langabeer; Gareth J Morgan
CYP1A1*2B (Val) allele is overrepresented in a subgroup of acute myeloid leukemia patients with poor-risk karyotype associated with NRAS mutation, but not associated with FLT3 internal tandem duplication.
Blood 2003;101(7):2770-4.
2002: Martyn T Smith; Yunxia Wang; Christine F Skibola; Diana J Slater; Luca Lo Nigro; Peter C Nowell; Beverly J Lange; Carolyn A Felix
Low NAD(P)H:quinone oxidoreductase activity is associated with increased risk of leukemia with MLL translocations in infants and children.
Blood 2002;100(13):4590-3.
2002: Nina T Holland; Paurene Duramad; Nathaniel Rothman; Larry W Figgs; Aaron Blair; Alan Hubbard; Martyn T Smith
Micronucleus frequency and proliferation in human lymphocytes after exposure to herbicide 2,4-dichlorophenoxyacetic acid in vitro and in vivo.
Mutation research 2002;521(1-2):165-78.
2002: Joseph L Wiemels; Brian C Leonard; Yunxia Wang; Mark Segal; Stephen P Hunger; Martyn T Smith; Vonda Crouse; Xiaomei Ma; Patricia A Buffler; Sharon R Pine
Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(23):15101-6.
2002: Xiaomei Ma; Patricia A Buffler; Robert B Gunier; Gary Dahl; Martyn T Smith; Kyndaron Reinier; Peggy Reynolds
Critical windows of exposure to household pesticides and risk of childhood leukemia.
Environmental health perspectives 2002;110(9):955-60.
2002: Joseph L Wiemels; Zhijian Xiao; Patricia A Buffler; Ana Teresa Maia; Xiaomei Ma; Brian M Dicks; Martyn T Smith; Luoping Zhang; James Feusner; John K Wiencke; Kathy Pritchard-Jones; Helena Kempski; Mel Greaves
In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemia.
Blood 2002;99(10):3801-5.
2002: Christine F Skibola; Martyn T Smith; Alan Hubbard; Barry Shane; Abby C Roberts; Graham Law; Sara Rollinson; Eve Roman; Ray A Cartwright; Gareth J Morgan
Polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and risk of adult acute lymphocytic leukemia.
Blood 2002;99(10):3786-91.
2002: John Curry; Cliona M McHale; Martyn T Smith
Low efficiency of the Moloney murine leukemia virus reverse transcriptase during reverse transcription of rare t(8;21) fusion gene transcripts.
BioTechniques 2002;32(4):768, 770, 772, 754-5.
2002: Gareth J Morgan; Martyn T Smith
Metabolic enzyme polymorphisms and susceptibility to acute leukemia in adults.
American journal of pharmacogenomics : genomics-related research in drug development and clinical practice 2002;2(2):79-92.
2002: Luoping Zhang; David A Eastmond; Martyn T Smith
The nature of chromosomal aberrations detected in humans exposed to benzene.
Critical reviews in toxicology 2002;32(1):1-42.
2001: John D Curry; M C Glaser; Martyn T Smith
Real-time reverse transcription polymerase chain reaction detection and quantification of t(1;19) (E2A-PBX1) fusion genes associated with leukaemia.
British journal of haematology 2001;115(4):826-30.
2001: S Zheng; Xiaomei Ma; Patricia A Buffler; Martyn T Smith; John K Wiencke
Whole genome amplification increases the efficiency and validity of buccal cell genotyping in pediatric populations.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(6):697-700.
2001: Richard Hayes; Luoping Zhang; James A Swenberg; SN Yin; Liqiang Xi; J Wiencke; William E Bechtold; M Yao; Nathaniel Rothman; R Haas; J P O'Neill; Joseph L Wiemels; Mustafa Dosemeci; Guilan Li; Martyn T Smith
Markers for carcinogenicity among butadiene-polymer workers in China.
Chemico-biological interactions 2001;135-136():455-64.
2001: Martyn T Smith; Y Wang; EV Kane; Sara Rollinson; Joseph L Wiemels; Eve Roman; Philippa L Roddam; Ray A Cartwright; G Morgan
Low NAD(P)H:quinone oxidoreductase 1 activity is associated with increased risk of acute leukemia in adults.
Blood 2001;97(5):1422-6.
2001: Martyn T Smith
Chromosome damage from biological reactive intermediates of benzene and 1,3-butadiene in leukemia.
Advances in experimental medicine and biology 2001;500():279-87.
2001: T A McDonald; Nina T Holland; C Skibola; Paurene Duramad; Martyn T Smith
Hypothesis: phenol and hydroquinone derived mainly from diet and gastrointestinal flora activity are causal factors in leukemia.
Leukemia 2001;15(1):10-20.
2000: Martyn T Smith; Nathaniel Rothman
Biomarkers in the molecular epidemiology of benzene-exposed workers.
Journal of toxicology and environmental health. Part A 2000;61(5-6):439-45.
2000: Richard Hayes; Songnian Yin; Nathaniel Rothman; Mustafa Dosemeci; Guilan Li; L T Travis; Martyn T Smith; Martha S Linet
Benzene and lymphohematopoietic malignancies in China.
Journal of toxicology and environmental health. Part A 2000;61(5-6):419-32.
2000: Martyn T Smith; Luoping Zhang; M Jeng; Y Wang; W Guo; Paurene Duramad; Alan E Hubbard; G Hofstadler; Nina T Holland
Hydroquinone, a benzene metabolite, increases the level of aneusomy of chromosomes 7 and 8 in human CD34-positive blood progenitor cells.
Carcinogenesis 2000;21(8):1485-90.
2000: Larry W Figgs; Nina T Holland; N Rothmann; S H Zahm; R E Tarone; R Hill; R F Vogt; Martyn T Smith; CD Boysen; F F Holmes; K VanDyck; A Blair
Increased lymphocyte replicative index following 2,4-dichlorophenoxyacetic acid herbicide exposure.
Cancer causes & control : CCC 2000;11(4):373-80.
2000: Richard Hayes; Luoping Zhang; Songnian Yin; James A Swenberg; Liqiang Xi; J Wiencke; William E Bechtold; M Yao; Nathaniel Rothman; R Haas; J P O'Neill; D Zhang; Joseph L Wiemels; Mustafa Dosemeci; Guilan Li; Martyn T Smith
Genotoxic markers among butadiene polymer workers in China.
Carcinogenesis 2000;21(1):55-62.
1999: Christine F Skibola; Martyn T Smith; EV Kane; Eve Roman; Sara Rollinson; Ray A Cartwright; G Morgan
Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12810-5.
1999: Martyn T Smith
Benzene, NQO1, and genetic susceptibility to cancer.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(14):7624-6.
1999: Joseph L Wiemels; John K Wiencke; A Varykoni; Martyn T Smith
Modulation of the toxicity and macromolecular binding of benzene metabolites by NAD(P)H:Quinone oxidoreductase in transfected HL-60 cells.
Chemical research in toxicology 1999;12(6):467-75.
1999: Nina Holland; T Ahlborn; K Turteltaub; C Markee; D Moore; Andrew J Wyrobek; Martyn T Smith
Acrylamide causes preimplantation abnormalities in embryos and induces chromatin-adducts in male germ cells of mice.
Reproductive toxicology (Elmsford, N.Y.) 1999;13(3):167-78.
1999: Joseph L Wiemels; Martyn T Smith
Enhancement of myeloid cell growth by benzene metabolites via the production of active oxygen species.
Free radical research 1999;30(2):93-103.
1999: Luoping Zhang; Nathaniel Rothman; Y Wang; Richard Hayes; Songnian Yin; N Titenko-Holland; M Dosemeci; Y Z Wang; P Kolachana; W Lu; Liqiang Xi; G L Li; Martyn T Smith
Benzene increases aneuploidy in the lymphocytes of exposed workers: a comparison of data obtained by fluorescence in situ hybridization in interphase and metaphase cells.
Environmental and molecular mutagenesis 1999;34(4):260-8.
1998: Luoping Zhang; Nathaniel Rothman; Y Wang; Richard Hayes; Guilan Li; M Dosemeci; Songnian Yin; P Kolachana; N Titenko-Holland; Martyn T Smith
Increased aneusomy and long arm deletion of chromosomes 5 and 7 in the lymphocytes of Chinese workers exposed to benzene.
Carcinogenesis 1998;19(11):1955-61.
1998: Nathaniel Rothman; William E Bechtold; SN Yin; Mustafa Dosemeci; GL Li; Y Z Wang; W C Griffith; Martyn T Smith; Richard Hayes
Urinary excretion of phenol, catechol, hydroquinone, and muconic acid by workers occupationally exposed to benzene.
Occupational and environmental medicine 1998;55(10):705-11.
1998: N Titenko-Holland; Robert A Jacob; N Shang; A Balaraman; Martyn T Smith
Micronuclei in lymphocytes and exfoliated buccal cells of postmenopausal women with dietary changes in folate.
Mutation research 1998;417(2-3):101-14.
1998: Martyn T Smith; Luoping Zhang
Biomarkers of leukemia risk: benzene as a model.
Environmental health perspectives 1998;106 Suppl 4():937-46.
1998: Martyn T Smith; Luoping Zhang; Y Wang; Richard Hayes; Guilan Li; Joseph L Wiemels; M Dosemeci; N Titenko-Holland; Liqiang Xi; P Kolachana; Songnian Yin; Nathaniel Rothman
Increased translocations and aneusomy in chromosomes 8 and 21 among workers exposed to benzene.
Cancer research 1998;58(10):2176-81.
1998: Luoping Zhang; Y Wang; N Shang; Martyn T Smith
Benzene metabolites induce the loss and long arm deletion of chromosomes 5 and 7 in human lymphocytes.
Leukemia research 1998;22(2):105-13.
1998: N Titenko-Holland; J Shao; Luoping Zhang; Liqiang Xi; H Ngo; N Shang; Martyn T Smith
Studies on the genotoxicity of molybdenum salts in human cells in vitro and in mice in vivo.
Environmental and molecular mutagenesis 1998;32(3):251-9.
1998: N Titenko-Holland; T Ahlborn; Xiu R Lowe; N Shang; Martyn T Smith; Andrew J Wyrobek
Micronuclei and developmental abnormalities in 4-day mouse embryos after paternal treatment with acrylamide.
Environmental and molecular mutagenesis 1998;31(3):206-17.
1997: Lee E Moore; Allan H Smith; Claudia Hopenhayn-Rich; Mary L Biggs; David Kalman; Martyn T Smith
Decrease in bladder cell micronucleus prevalence after intervention to lower the concentration of arsenic in drinking water.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(12):1051-6.
1997: Liqiang Xi; Luoping Zhang; Y Wang; Martyn T Smith
Induction of chromosome-specific aneuploidy and micronuclei in human lymphocytes by metabolites of 1,3-butadiene.
Carcinogenesis 1997;18(9):1687-93.
1997: Nathaniel Rothman; Martyn T Smith; Richard Hayes; R D Traver; B Hoener; Sharan L Campleman; GL Li; Mustafa Dosemeci; Martha Linet; Li Zhang; Liqiang Xi; Sholom Wacholder; W Lu; K B Meyer; N Titenko-Holland; J T Stewart; Songnian Yin; D Ross
Benzene poisoning, a risk factor for hematological malignancy, is associated with the NQO1 609C-->T mutation and rapid fractional excretion of chlorzoxazone.
Cancer research 1997;57(14):2839-42.
1997: Mary L Biggs; David Kalman; Lee E Moore; Claudia Hopenhayn-Rich; Martyn T Smith; Allan H Smith
Relationship of urinary arsenic to intake estimates and a biomarker of effect, bladder cell micronuclei.
Mutation research 1997;386(3):185-95.
1997: Martyn T Smith; E W Fanning
Report on the workshop entitled: "Modeling chemically induced leukemia--implications for benzene risk assessment".
Leukemia research 1997;21(5):361-74.
1997: N Titenko-Holland; GC Windham; P Kolachana; F Reinisch; S Parvatham; A M Osorio; Martyn T Smith
Genotoxicity of malathion in human lymphocytes assessed using the micronucleus assay in vitro and in vivo: a study of malathion-exposed workers.
Mutation research 1997;388(1):85-95.
1997: Lee E Moore; Allan H Smith; Claudia Hopenhayn-Rich; Mary L Biggs; David Kalman; Martyn T Smith
Micronuclei in exfoliated bladder cells among individuals chronically exposed to arsenic in drinking water.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(1):31-6.
1996: N Titenko-Holland; A J Levine; Martyn T Smith; P J Quintana; Mark F Boeniger; R Hayes; A Suruda; Paul A Schulte
Quantification of epithelial cell micronuclei by fluorescence in situ hybridization (FISH) in mortuary science students exposed to formaldehyde.
Mutation research 1996;371(3-4):237-48.
1996: Frederic Yves Bois; E T Jackson; K Pekari; Martyn T Smith
Population toxicokinetics of benzene.
Environmental health perspectives 1996;104 Suppl 6():1405-11.
1996: Nathaniel Rothman; Martyn T Smith; Richard Hayes; GL Li; Richard D Irons; M Dosemeci; R Haas; WS Stillman; M Linet; Liqiang Xi; William E Bechtold; Joseph L Wiemels; S Campleman; L Zhang; P J Quintana; N Titenko-Holland; Y Z Wang; W Lu; P Kolachana; K B Meyer; Songnian Yin
An epidemiologic study of early biologic effects of benzene in Chinese workers.
Environmental health perspectives 1996;104 Suppl 6():1365-70.
1996: L Zhang; Nathaniel Rothman; Y Wang; Richard Hayes; W Bechtold; P Venkatesh; Songnian Yin; Y Wang; M Dosemeci; Guilan Li; W Lu; Martyn T Smith
Interphase cytogenetics of workers exposed to benzene.
Environmental health perspectives 1996;104 Suppl 6():1325-9.
1996: Martyn T Smith
The mechanism of benzene-induced leukemia: a hypothesis and speculations on the causes of leukemia.
Environmental health perspectives 1996;104 Suppl 6():1219-25.
1996: J Shao; L Zhang; J C Semenza; B Beach; Martyn T Smith
Tetrasomy 8 detected by interphase cytogenetics in a child with acute lymphocytic leukemia.
Cancer genetics and cytogenetics 1996;92(2):135-40.
1996: Richard Hayes; Liqiang Xi; William E Bechtold; Nathaniel Rothman; M Yao; R Henderson; L Zhang; Martyn T Smith; D Zhang; Joseph L Wiemels; M Dosemeci; Songnian Yin; J P O'Neill
hprt mutation frequency among workers exposed to 1,3-butadiene in China.
Toxicology 1996;113(1-3):100-5.
1996: Nathaniel Rothman; GL Li; M Dosemeci; William E Bechtold; G E Marti; Y Z Wang; M Linet; L Q Xi; W Lu; Martyn T Smith; N Titenko-Holland; L P Zhang; William J Blot; SN Yin; Richard Hayes
Hematotoxicity among Chinese workers heavily exposed to benzene.
American journal of industrial medicine 1996;29(3):236-46.
1996: Martyn T Smith
Overview of benzene-induced aplastic anaemia.
European journal of haematology. Supplementum 1996;60():107-10.
1996: Martyn T Smith
Mechanistic studies of benzene toxicity -- implications for risk assessment.
Advances in experimental medicine and biology 1996;387():259-66.
1996: Lee E Moore; M L Warner; Allan H Smith; David Kalman; Martyn T Smith
Use of the fluorescent micronucleus assay to detect the genotoxic effects of radiation and arsenic exposure in exfoliated human epithelial cells.
Environmental and molecular mutagenesis 1996;27(3):176-84.
1994: M L Warner; Lee E Moore; Martyn T Smith; David Kalman; E Fanning; Allan H Smith
Increased micronuclei in exfoliated bladder cells of individuals who chronically ingest arsenic-contaminated water in Nevada.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1994;3(7):583-90.
1994: P Kolachana; Martyn T Smith
Induction of kinetochore-positive micronuclei in human lymphocytes by the anti-fungal drug griseofulvin.
Mutation research 1994;322(3):151-9.
1994: L Zhang; P Venkatesh; M L Creek; Martyn T Smith
Detection of 1,2,4-benzenetriol induced aneuploidy and microtubule disruption by fluorescence in situ hybridization and immunocytochemistry.
Mutation research 1994;320(4):315-27.
1994: N Titenko-Holland; Lee E Moore; Martyn T Smith
Measurement and characterization of micronuclei in exfoliated human cells by fluorescence in situ hybridization with a centromeric probe.
Mutation research 1994;312(1):39-50.
1994: Martyn T Smith; W A Suk
Application of molecular biomarkers in epidemiology.
Environmental health perspectives 1994;102 Suppl 1():229-35.
1993: Lee E Moore; N Titenko-Holland; P J Quintana; Martyn T Smith
Novel biomarkers of genetic damage in humans: use of fluorescence in situ hybridization to detect aneuploidy and micronuclei in exfoliated cells.
Journal of toxicology and environmental health 1993;40(2-3):349-57.
1993: Allan H Smith; Claudia Hopenhayn-Rich; M Warner; Mary L Biggs; L Moore; Martyn T Smith
Rationale for selecting exfoliated bladder cell micronuclei as potential biomarkers for arsenic genotoxicity.
Journal of toxicology and environmental health 1993;40(2-3):223-34.
1993: P Kolachana; Subrahmanyam Vangala; K B Meyer; L Zhang; Martyn T Smith
Benzene and its phenolic metabolites produce oxidative DNA damage in HL60 cells in vitro and in the bone marrow in vivo.
Cancer research 1993;53(5):1023-6.
1993: P J Compton-Quintana; R H Jensen; William L Bigbee; S G Grant; Richard G Langlois; Martyn T Smith; Stephen M Rappaport
Use of the glycophorin A human mutation assay to study workers exposed to styrene.
Environmental health perspectives 1993;99():297-301.
1993: L Zhang; M L Robertson; P Kolachana; A J Davison; Martyn T Smith
Benzene metabolite, 1,2,4-benzenetriol, induces micronuclei and oxidative DNA damage in human lymphocytes and HL60 cells.
Environmental and molecular mutagenesis 1993;21(4):339-48.
1993: M S Sandy; J William Langston; Martyn T Smith; Donato A Di Monte
PCR analysis of platelet mtDNA: lack of specific changes in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 1993;8(1):74-82.
1993: Lee E Moore; N Titenko-Holland; Martyn T Smith
Use of fluorescence in situ hybridization to detect chromosome-specific changes in exfoliated human bladder and oral mucosa cells.
Environmental and molecular mutagenesis 1993;22(3):130-7.
1992: Allan H Smith; Claudia Hopenhayn-Rich; M N Bates; H M Goeden; Irva Hertz-Picciotto; H M Duggan; R Wood; M J Kosnett; Martyn T Smith
Cancer risks from arsenic in drinking water.
Environmental health perspectives 1992;97():259-67.
1992: K Mithöfer; M S Sandy; Martyn T Smith; Donato A Di Monte
Mitochondrial poisons cause depletion of reduced glutathione in isolated hepatocytes.
Archives of biochemistry and biophysics 1992;295(1):132-6.
1991: P J Compton; K Hooper; Martyn T Smith
Human somatic mutation assays as biomarkers of carcinogenesis.
Environmental health perspectives 1991;94():135-41.
1991: M L Robertson; D A Eastmond; Martyn T Smith
Two benzene metabolites, catechol and hydroquinone, produce a synergistic induction of micronuclei and toxicity in cultured human lymphocytes.
Mutation research 1991;249(1):201-9.
1991: Frederic Yves Bois; Martyn T Smith; R C Spear
Mechanisms of benzene carcinogenesis: application of a physiological model of benzene pharmacokinetics and metabolism.
Toxicology letters 1991;56(3):283-98.
1991: Subrahmanyam Vangala; P Kolachana; Martyn T Smith
Metabolism of hydroquinone by human myeloperoxidase: mechanisms of stimulation by other phenolic compounds.
Archives of biochemistry and biophysics 1991;286(1):76-84.
1991: D Ting; Martyn T Smith; P Doane-Setzer; J Woodlee; Stephen M Rappaport
Measurement of styrene-oxide cysteine adducts in hemoglobin by selective catalytic reduction.
Advances in experimental medicine and biology 1991;283():837-41.
1991: P Kolachana; Subrahmanyam Vangala; D A Eastmond; Martyn T Smith
Metabolism of phenylhydroquinone by prostaglandin (H) synthase: possible implications in o-phenylphenol carcinogenesis.
Carcinogenesis 1991;12(1):145-9.
1991: Subrahmanyam Vangala; D Ross; D A Eastmond; Martyn T Smith
Potential role of free radicals in benzene-induced myelotoxicity and leukemia.
Free radical biology & medicine 1991;11(5):495-515.
1991: Subrahmanyam Vangala; P Kolachana; Martyn T Smith
Hydroxylation of phenol to hydroquinone catalyzed by a human myeloperoxidase-superoxide complex: possible implications in benzene-induced myelotoxicity.
Free radical research communications 1991;15(5):285-96.
1991: Subrahmanyam Vangala; P Kolachana; Martyn T Smith
Effect of phenol and catechol on the kinetics of human myeloperoxidase-dependent hydroquinone metabolism.
Advances in experimental medicine and biology 1991;283():377-81.
1990: E Y Wu; Martyn T Smith; G Bellomo; Donato A Di Monte
Relationships between the mitochondrial transmembrane potential, ATP concentration, and cytotoxicity in isolated rat hepatocytes.
Archives of biochemistry and biophysics 1990;282(2):358-62.
1990: Subrahmanyam Vangala; P Doane-Setzer; K L Steinmetz; D Ross; Martyn T Smith
Phenol-induced stimulation of hydroquinone bioactivation in mouse bone marrow in vivo: possible implications in benzene myelotoxicity.
Toxicology 1990;62(1):107-16.
1990: D Ting; Martyn T Smith; P Doane-Setzer; Stephen M Rappaport
Analysis of styrene oxide-globin adducts based upon reaction with Raney nickel.
Carcinogenesis 1990;11(5):755-60.
1990: J W Yager; D A Eastmond; M L Robertson; W M Paradisin; Martyn T Smith
Characterization of micronuclei induced in human lymphocytes by benzene metabolites.
Cancer research 1990;50(2):393-9.
1990: Martyn T Smith; M L Robertson; J W Yager; D A Eastmond
Role of metabolism in benzene-induced myelotoxicity and leukemogenesis.
Progress in clinical and biological research 1990;340B():125-36.
1989: Donato A Di Monte; E Y Wu; Martyn T Smith
Commentary on "Biochemical mechanism of action of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)'.
Toxicology letters 1989;48(2):117-9.
1989: Martyn T Smith; J W Yager; K L Steinmetz; D A Eastmond
Peroxidase-dependent metabolism of benzene's phenolic metabolites and its potential role in benzene toxicity and carcinogenicity.
Environmental health perspectives 1989;82():23-9.
1989: Martyn T Smith; C G Evans; P Doane-Setzer; V M Castro; M K Tahir; B Mannervik
Denitrosation of 1,3-bis(2-chloroethyl)-1-nitrosourea by class mu glutathione transferases and its role in cellular resistance in rat brain tumor cells.
Cancer research 1989;49(10):2621-5.
1988: Donato A Di Monte; M S Sandy; L Blank; Martyn T Smith
Fructose prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced ATP depletion and toxicity in isolated hepatocytes.
Biochemical and biophysical research communications 1988;153(2):734-40.
1988: M S Sandy; Donato A Di Monte; Martyn T Smith
Relationships between intracellular vitamin E, lipid peroxidation, and chemical toxicity in hepatocytes.
Toxicology and applied pharmacology 1988;93(2):288-97.
1988: Donato A Di Monte; T Shinka; M S Sandy; Neal Castagnoli; Martyn T Smith
Quantitative analysis of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolism in isolated rat hepatocytes.
Drug metabolism and disposition: the biological fate of chemicals 1988;16(2):250-5.
1988: M S Sandy; Donato A Di Monte; P Cohen; Martyn T Smith
Role of active oxygen in paraquat and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) cytotoxicity.
Basic life sciences 1988;49():795-801.
1987: M S Sandy; P Moldeus; D Ross; Martyn T Smith
Cytotoxicity of the redox cycling compound diquat in isolated hepatocytes: involvement of hydrogen peroxide and transition metals.
Archives of biochemistry and biophysics 1987;259(1):29-37.
1987: Donato A Di Monte; M S Sandy; Martyn T Smith
Increased efflux rather than oxidation is the mechanism of glutathione depletion by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Biochemical and biophysical research communications 1987;148(1):153-60.
1987: D A Eastmond; Martyn T Smith; R D Irons
An interaction of benzene metabolites reproduces the myelotoxicity observed with benzene exposure.
Toxicology and applied pharmacology 1987;91(1):85-95.
1987: G Ekström; Donato A Di Monte; M S Sandy; Martyn T Smith
Comparative toxicity and antioxidant activity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its monoamine oxidase B-generated metabolites in isolated hepatocytes and liver microsomes.
Archives of biochemistry and biophysics 1987;255(1):14-8.
1987: C G Evans; W J Bodell; K Tokuda; P Doane-Setzer; Martyn T Smith
Glutathione and related enzymes in rat brain tumor cell resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea and nitrogen mustard.
Cancer research 1987;47(10):2525-30.
1987: Martyn T Smith; G Ekström; M S Sandy; Donato A Di Monte
Studies on the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine cytotoxicity in isolated hepatocytes.
Life sciences 1987;40(8):741-8.
1987: Martyn T Smith; M S Sandy; Donato A Di Monte
Free radicals, lipid peroxidation, and Parkinson's disease.
Lancet 1987;1(8523):38.
1987: Donato A Di Monte; G Ekström; T Shinka; Martyn T Smith; A J Trevor; Neal Castagnoli
Role of 1-methyl-4-phenylpyridinium ion formation and accumulation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity to isolated hepatocytes.
Chemico-biological interactions 1987;62(2):105-16.
1987: D A Eastmond; R C French; D Ross; Martyn T Smith
Metabolic activation of 1-naphthol and phenol by a simple superoxide-generating system and human leukocytes.
Chemico-biological interactions 1987;63(1):47-62.
1986: M S Sandy; P Moldeus; D Ross; Martyn T Smith
Role of redox cycling and lipid peroxidation in bipyridyl herbicide cytotoxicity. Studies with a compromised isolated hepatocyte model system.
Biochemical pharmacology 1986;35(18):3095-101.
1986: Donato A Di Monte; S A Jewell; G Ekström; M S Sandy; Martyn T Smith
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridine (MPP+) cause rapid ATP depletion in isolated hepatocytes.
Biochemical and biophysical research communications 1986;137(1):310-5.
1986: Donato A Di Monte; M S Sandy; G Ekström; Martyn T Smith
Comparative studies on the mechanisms of paraquat and 1-methyl-4-phenylpyridine (MPP+) cytotoxicity.
Biochemical and biophysical research communications 1986;137(1):303-9.