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Nicolas Smith

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Publications

TOP 3
Eoin R Hyde; Jack Lee; Christian Michler; David A Nordsletten; Radek Chabiniok; Andrew N Cookson; Nicolas P Smith
Parameterisation of multi-scale continuum perfusion models from discrete vascular networks.
Sander Land; William E Louch; Steven A Niederer; Ole M Sejersted; Ivar Sjaastad; Jan Magnus Aronsen; Geir Christensen; Nicolas P Smith
Beta-adrenergic stimulation maintains cardiac function in Serca2 knockout mice.
Liren Li; William E Louch; Steven A Niederer; Ole M Sejersted; Jan M Aronsen; Geir Christensen; Nicolas P Smith
Sodium accumulation in SERCA knockout-induced heart failure.

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All Publications

2013: Eoin R Hyde; Jack Lee; Christian Michler; David A Nordsletten; Radek Chabiniok; Andrew N Cookson; Nicolas P Smith
Parameterisation of multi-scale continuum perfusion models from discrete vascular networks.
Medical & biological engineering & computing 2013;51(5):557-70.
2013: Sander Land; William E Louch; Steven A Niederer; Ole M Sejersted; Ivar Sjaastad; Jan Magnus Aronsen; Geir Christensen; Nicolas P Smith
Beta-adrenergic stimulation maintains cardiac function in Serca2 knockout mice.
Biophysical journal 2013;104(6):1349-56.
2012: Liren Li; William E Louch; Steven A Niederer; Ole M Sejersted; Jan M Aronsen; Geir Christensen; Nicolas P Smith
Sodium accumulation in SERCA knockout-induced heart failure.
Biophysical journal 2012;102(9):2039-48.
2012: Sander Land; Steven A Niederer; Nicolas P Smith
Efficient computational methods for strongly coupled cardiac electromechanics.
IEEE transactions on bio-medical engineering 2012;59(5):1219-28.
2012: Steven A Niederer; Gernot Plank; R Razavi; A K Shetty; Nicolas P Smith; J Bostock; C A Rinaldi
Biophysical modeling to simulate the response to multisite left ventricular stimulation using a quadripolar pacing lead.
Pacing and clinical electrophysiology : PACE 2012;35(2):204-14.
2011: O Camara; M De Craene; Hervé Delingette; A F Frangi; P Lamata; H Liu; Steven A Niederer; A Pashaei; G Plank; M Pop; J Relan; D Romero; R Sebastian; Maxime Sermesant; P Shi; Nicolas P Smith; L Wang; K C L Wong; N Ayache; H Zhang; G A Wright
Inter-model consistency and complementarity: learning from ex-vivo imaging and electrophysiological data towards an integrated understanding of cardiac physiology.
Progress in biophysics and molecular biology 2011;107(1):122-33.
2011: L Li; W E Louch; Steven A Niederer; K B Andersson; G Christensen; Ole M Sejersted; Nicolas P Smith
Calcium dynamics in the ventricular myocytes of SERCA2 knockout mice: A modeling study.
Biophysical journal 2011;100(2):322-31.
2011: Martin Fink; Steven A Niederer; Elizabeth M Cherry; Flavio H Fenton; Jussi T Koivumäki; Gunnar Seemann; Rüdiger Thul; Henggui Zhang; Frank B Sachse; Dan Beard; Edmund J Crampin; Nicolas P Smith
Cardiac cell modelling: observations from the heart of the cardiac physiome project.
Progress in biophysics and molecular biology 2011;104(1-3):2-21.
2011: D A Nordsletten; Steven A Niederer; Martyn P Nash; Peter J Hunter; Nicolas P Smith
Coupling multi-physics models to cardiac mechanics.
Progress in biophysics and molecular biology 2011;104(1-3):77-88.
2010: L Li; Steven A Niederer; W Idigo; Y H Zhang; Pawel Swietach; Barbara Casadei; Nicolas P Smith
A mathematical model of the murine ventricular myocyte: a data-driven biophysically based approach applied to mice overexpressing the canine NCX isoform.
American journal of physiology. Heart and circulatory physiology 2010;299(4):H1045-63.
2010: Hayley Reynolds; Cameron Walker; P Rod Dunbar; Michael J O'Sullivan; Roger F Uren; John F Thompson; Nicolas P Smith
Functional anatomy of the lymphatics draining the skin: a detailed statistical analysis.
Journal of anatomy 2010;216(3):344-55.
2010: Kenneth Tran; Nicolas P Smith; Denis S Loiselle; Edmund J Crampin
A metabolite-sensitive, thermodynamically constrained model of cardiac cross-bridge cycling: implications for force development during ischemia.
Biophysical journal 2010;98(2):267-76.
2009: Hayley Reynolds; Nicolas P Smith; Roger F Uren; John F Thompson; P Rod Dunbar
Three-dimensional visualization of skin lymphatic drainage patterns of the head and neck.
Head & neck 2009;31(10):1316-25.
2009: R A Faville; Andrew J Pullan; K M Sanders; S D Koh; C M Lloyd; Nicolas P Smith
Biophysically based mathematical modeling of interstitial cells of Cajal slow wave activity generated from a discrete unitary potential basis.
Biophysical journal 2009;96(12):4834-52.
2009: Steven A Niederer; H E D J Ter Keurs; Nicolas P Smith
Modelling and measuring electromechanical coupling in the rat heart.
Experimental physiology 2009;94(5):529-40.
2009: Steven A Niederer; Martin Fink; Denis Noble; Nicolas P Smith
A meta-analysis of cardiac electrophysiology computational models.
Experimental physiology 2009;94(5):486-95.
2009: Steven A Niederer; Nicolas P Smith
The role of the Frank-Starling law in the transduction of cellular work to whole organ pump function: a computational modeling analysis.
PLoS computational biology 2009;5(4):e1000371.
2009: Kenneth Tran; Nicolas P Smith; Denis S Loiselle; Edmund J Crampin
A thermodynamic model of the cardiac sarcoplasmic/endoplasmic Ca(2+) (SERCA) pump.
Biophysical journal 2009;96(5):2029-42.
2008: Jack Lee; Nicolas P Smith
Theoretical modeling in hemodynamics of microcirculation.
Microcirculation (New York, N.Y. : 1994) 2008;15(8):699-714.
2008: Jonna R Terkildsen; Steven A Niederer; Edmund J Crampin; Peter Hunter; Nicolas P Smith
Using Physiome standards to couple cellular functions for rat cardiac excitation-contraction.
Experimental physiology 2008;93(7):919-29.
2008: R A Faville; A J Pullan; K M Sanders; Nicolas P Smith
A biophysically based mathematical model of unitary potential activity in interstitial cells of Cajal.
Biophysical journal 2008;95(1):88-104.
2008: Denis S Loiselle; Edmund J Crampin; Steven A Niederer; Nicolas P Smith; C J Barclay
Energetic consequences of mechanical loads.
Progress in biophysics and molecular biology 2008;97(2-3):348-66.
2008: Steven A Niederer; Pawel Swietach; D A Wilson; Nicolas P Smith; Richard D Vaughan-Jones
Measuring and modeling chloride-hydroxyl exchange in the Guinea-pig ventricular myocyte.
Biophysical journal 2008;94(6):2385-403.
2008: Steven A Niederer; Nicolas P Smith
An improved numerical method for strong coupling of excitation and contraction models in the heart.
Progress in biophysics and molecular biology 2008;96(1-3):90-111.
2007: Jonna R Terkildsen; Edmund J Crampin; Nicolas P Smith
The balance between inactivation and activation of the Na+-K+ pump underlies the triphasic accumulation of extracellular K+ during myocardial ischemia.
American journal of physiology. Heart and circulatory physiology 2007;293(5):H3036-45.
2007: Hayley Reynolds; P Rod Dunbar; Roger F Uren; Shane A Blackett; John F Thompson; Nicolas P Smith
Three-dimensional visualisation of lymphatic drainage patterns in patients with cutaneous melanoma.
The lancet oncology 2007;8(9):806-12.
2007: Hayley Reynolds; P Rod Dunbar; Roger F Uren; John F Thompson; Nicolas P Smith
Mapping melanoma lymphoscintigraphy data onto a 3D anatomically based model.
Annals of biomedical engineering 2007;35(8):1444-57.
2007: Steven A Niederer; Nicolas P Smith
A mathematical model of the slow force response to stretch in rat ventricular myocytes.
Biophysical journal 2007;92(11):4030-44.
2007: Nicolas P Smith; Edmund J Crampin; Steven A Niederer; James B Bassingthwaighte; Daniel A Beard
Computational biology of cardiac myocytes: proposed standards for the physiome.
The Journal of experimental biology 2007;210(Pt 9):1576-83.
2007: Sarah L Cox; Kumar Mithraratne; Nicolas P Smith
An anatomically based finite element model of the lower limbs in the seated posture.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2007;2007():6327-30.
2006: Rebecca A B Burton; Gernot Plank; Jürgen E Schneider; Vicente Grau; Helmut Ahammer; Stephen L Keeling; Jack Lee; Nicolas P Smith; David J Gavaghan; Natalia Trayanova; Tahir Mansoori
Three-dimensional models of individual cardiac histoanatomy: tools and challenges.
Annals of the New York Academy of Sciences 2006;1080():301-19.
2006: Anita Shu-Han Lin; Martin L Buist; Nicolas P Smith; Andrew J Pullan
Modelling slow wave activity in the small intestine.
Journal of theoretical biology 2006;242(2):356-62.
2006: Anita Shu-Han Lin; Martin L Buist; Leo Cheng; Nicolas P Smith; Andrew J Pullan
Computational simulations of the human magneto- and electroenterogram.
Annals of biomedical engineering 2006;34(8):1322-31.
2006: David A Nordsletten; Shane Blackett; Michael D Bentley; Erik L Ritman; Nicolas P Smith
Structural morphology of renal vasculature.
American journal of physiology. Heart and circulatory physiology 2006;291(1):H296-309.
2006: Edmund J Crampin; Nicolas P Smith; A Elise Langham; Richard H Clayton; Clive H Orchard
Acidosis in models of cardiac ventricular myocytes.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 2006;364(1842):1171-86.
2006: Edmund J Crampin; Nicolas P Smith
A dynamic model of excitation-contraction coupling during acidosis in cardiac ventricular myocytes.
Biophysical journal 2006;90(9):3074-90.
2006: Steven A Niederer; Peter J Hunter; Nicolas P Smith
A quantitative analysis of cardiac myocyte relaxation: a simulation study.
Biophysical journal 2006;90(5):1697-722.
2006: T D S Mabotuwana; Leo Cheng; Nicolas P Smith; Andrew J Pullan
Modeling blood flow in the gastrointestinal system.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2006;1():1810-3.
2006: Hayley Reynolds; P Rod Dunbar; Roger F Uren; Nicolas P Smith
Computer modeling provides a new tool for clinically diagnosing melanoma spread through the lymphatics.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2006;1():5307-10.
2005: Nicolas P Smith; Christopher J Barclay; Denis S Loiselle
The efficiency of muscle contraction.
Progress in biophysics and molecular biology 2005;88(1):1-58.
2005: Martin L Buist; Nicolas P Smith; Andrew J Pullan
Cardiac electromechanics and the forward/inverse problems of electrocardiology.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2005;7():7198-200.
2004: Edmund J Crampin; Nicolas P Smith; Peter J Hunter
Multi-scale modelling and the IUPS physiome project.
Journal of molecular histology 2004;35(7):707-14.
2004: Nicolas P Smith
A computational study of the interaction between coronary blood flow and myocardial mechanics.
Physiological measurement 2004;25(4):863-77.
2004: Nicolas P Smith; Edmund J Crampin
Development of models of active ion transport for whole-cell modelling: cardiac sodium-potassium pump as a case study.
Progress in biophysics and molecular biology 2004;85(2-3):387-405.
2004: Nicolas P Smith; Edmund J Crampin
Modelling cellular and tissue function.
Progress in biophysics and molecular biology 2004;85(2-3):117-9.
2004: Anita Shu-Han Lin; Nicolas P Smith; Andrew J Pullan; Martin L Buist
An anatomically based model of small intestine excitation.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2004;2():887-9.
2004: Rita Yassi; Leo Cheng; Saad Al-Ali; Nicolas P Smith; Andrew J Pullan; John Windsor
An anatomically based mathematical model of the gastroesophageal junction.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2004;1():635-8.
2004: J C J Lee; Andrew J Pullan; Nicolas P Smith
A computational model of microcirculatory network structure and transient coronary microcirculation.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2004;5():3808-11.
2004: Steven A Niederer; Martin L Buist; Andrew J Pullan; Nicolas P Smith
Computing work in the ischemic heart.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2004;5():3646-9.
2003: Nicolas P Smith
From sarcomere to cell: an efficient algorithm for linking mathematical models of muscle contraction.
Bulletin of mathematical biology 2003;65(6):1141-62.
2003: Nicolas P Smith; Martin L Buist; Andrew J Pullan
Altered T wave dynamics in a contracting cardiac model.
Journal of cardiovascular electrophysiology 2003;14(10 Suppl):S203-9.
2003: Andrew J Pullan; Martin L Buist; Gregory Sands; Leo Cheng; Nicolas P Smith
Cardiac electrical activity--from heart to body surface and back again.
Journal of electrocardiology 2003;36 Suppl():63-7.
2000: Nicolas P Smith; Andrew J Pullan; Peter J Hunter
Generation of an anatomically based geometric coronary model.
Annals of biomedical engineering 2000;28(1):14-25.