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Patrice Smith

Research Profile

Chemicals & Drugs

Physiology

Cell Death

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Publications

TOP 3
Matthew P Mount; Arman Lira; David Grimes; Patrice D Smith; Sylvie Faucher; Ruth Slack; Hymie Anisman; Shawn Hayley; David Park
Involvement of interferon-gamma in microglial-mediated loss of dopaminergic neurons.
Patrice D Smith; Matthew P Mount; Raj Shree; Steven M Callaghan; ruth slack; Hymie Anisman; Inez Vincent; Xuemin Wang; Zixu Mao; David Park
Calpain-regulated p35/cdk5 plays a central role in dopaminergic neuron death through modulation of the transcription factor myocyte enhancer factor 2.
Stephen J Crocker; Shawn Hayley; Patrice D Smith; Matthew P Mount; Wiplove R Lamba; Steven M Callaghan; ruth slack; David Park
Regulation of axotomy-induced dopaminergic neuron death and c-Jun phosphorylation by targeted inhibition of cdc42 or mixed lineage kinase.

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All Publications

2007: Matthew P Mount; Arman Lira; David Grimes; Patrice D Smith; Sylvie Faucher; Ruth Slack; Hymie Anisman; Shawn Hayley; David Park
Involvement of interferon-gamma in microglial-mediated loss of dopaminergic neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(12):3328-37.
2006: Patrice D Smith; Matthew P Mount; Raj Shree; Steven M Callaghan; ruth slack; Hymie Anisman; Inez Vincent; Xuemin Wang; Zixu Mao; David Park
Calpain-regulated p35/cdk5 plays a central role in dopaminergic neuron death through modulation of the transcription factor myocyte enhancer factor 2.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(2):440-7.
2006: Stephen J Crocker; Shawn Hayley; Patrice D Smith; Matthew P Mount; Wiplove R Lamba; Steven M Callaghan; ruth slack; David Park
Regulation of axotomy-induced dopaminergic neuron death and c-Jun phosphorylation by targeted inhibition of cdc42 or mixed lineage kinase.
Journal of neurochemistry 2006;96(2):489-99.
2005: Raymond H Kim; Patrice D Smith; Hossein Aleyasin; Shawn Hayley; Matthew P Mount; Scott Pownall; Andrew Wakeham; Annick J You-Ten; Suneil K Kalia; Patrick Horne; David Westaway; Andres M Lozano; Hymie Anisman; David Park; Tak W Mak
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(14):5215-20.
2004: Suneil K Kalia; Sang Lee; Patrice D Smith; Li Liu; Stephen J Crocker; Thorhildur E Thorarinsdottir; John R Glover; Edward A Fon; David Park; Andres M Lozano
BAG5 inhibits parkin and enhances dopaminergic neuron degeneration.
Neuron 2004;44(6):931-45.
2004: Patrice D Smith; Michael J O'Hare; David Park
CDKs: taking on a role as mediators of dopaminergic loss in Parkinson's disease.
Trends in molecular medicine 2004;10(9):445-51.
2004: Patrice D Smith; Michael J O'Hare; David Park
Emerging pathogenic role for cyclin dependent kinases in neurodegeneration.
Cell cycle (Georgetown, Tex.) 2004;3(3):289-91.
2004: Shawn Hayley; Stephen J Crocker; Patrice D Smith; Tanaya Shree; Vernice Jackson-Lewis; Serge Przedborski; Matthew P Mount; Ruth Slack; Hymie Anisman; David Park
Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(8):2045-53.
2003: Patrice D Smith; Stephen J Crocker; Vernice Jackson-Lewis; Kelly L Jordan-Sciutto; Shawn Hayley; Matthew P Mount; Michael J O'Hare; Steven M Callaghan; ruth slack; Serge Przedborski; Hymie Anisman; David Park
Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(23):13650-5.
2003: Stephen J Crocker; Patrice D Smith; Vernice Jackson-Lewis; Wiplove R Lamba; Shawn Hayley; Erich Grimm; Steven M Callaghan; ruth slack; Edon Melloni; Serge Przedborski; George S Robertson; Hymie Anisman; Zul Merali; David Park
Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(10):4081-91.
2003: Stephen J Crocker; Peter Liston; Hymie Anisman; C J Lee; Patrice D Smith; N Earl; Charlie S Thompson; David Park; Robert G Korneluk; George S Robertson
Attenuation of MPTP-induced neurotoxicity and behavioural impairment in NSE-XIAP transgenic mice.
Neurobiology of disease 2003;12(2):150-61.
2001: Stephen J Crocker; Wiplove R Lamba; Patrice D Smith; Steven M Callaghan; ruth slack; Hymie Anisman; David Park
c-Jun mediates axotomy-induced dopamine neuron death in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):13385-90.