FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Richard Smith

Research Profile

Living Beings

Physiology

Disorders

Procedures

Anatomy

Chemicals & Drugs

Eye Proteins

Co-author Network

Publications

TOP 3
Xianjun Zhu; Roderick T Bronson; Wilhelmine N de Vries; Richard T Libby; Kevin Seburn; Richard S Smith; Dana L Wright; Simon W M John
Mutations in a P-type ATPase gene cause axonal degeneration.
K Saidas Nair; Mounira Hmani-Aifa; Zain Ali; Alison L Kearney; Danilo G Macalinao; Ioan M Cosma; Walid Bouassida; Bochra Hakim; Zeineb Benzina; Ileana Soto; Peter Söderkvist; Gareth R Howell; Richard S Smith; Hammadi Ayadi; Salma Ben Salem; Simon W M John
Alteration of the serine protease PRSS56 causes angle-closure glaucoma in mice and posterior microphthalmia in humans and mice.
Jungyeon Won; Caralina Marín de Evsikova; Richard S Smith; Wanda L Hicks; Malia M Edwards; Chantal M Longo-Guess; Tiansen Li; Jürgen K Naggert; Patsy M Nishina
NPHP4 is necessary for normal photoreceptor ribbon synapse maintenance and outer segment formation, and for sperm development.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Richard Smith (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Xianjun Zhu; Roderick T Bronson; Wilhelmine N de Vries; Richard T Libby; Kevin Seburn; Richard S Smith; Dana L Wright; Simon W M John
Mutations in a P-type ATPase gene cause axonal degeneration.
PLoS genetics 2012;8(8):e1002853.
2011: K Saidas Nair; Mounira Hmani-Aifa; Zain Ali; Alison L Kearney; Danilo G Macalinao; Ioan M Cosma; Walid Bouassida; Bochra Hakim; Zeineb Benzina; Ileana Soto; Peter Söderkvist; Gareth R Howell; Richard S Smith; Hammadi Ayadi; Salma Ben Salem; Simon W M John
Alteration of the serine protease PRSS56 causes angle-closure glaucoma in mice and posterior microphthalmia in humans and mice.
Nature genetics 2011;43(6):579-84.
2011: Jungyeon Won; Caralina Marín de Evsikova; Richard S Smith; Wanda L Hicks; Malia M Edwards; Chantal M Longo-Guess; Tiansen Li; Jürgen K Naggert; Patsy M Nishina
NPHP4 is necessary for normal photoreceptor ribbon synapse maintenance and outer segment formation, and for sperm development.
Human molecular genetics 2011;20(3):482-96.
2011: YongSuk Lee; Richard S Smith; Wanda Jordan; Benjamin L King; Jungyeon Won; Jose M Valpuesta; Jürgen K Naggert; Patsy M Nishina
Prefoldin 5 is required for normal sensory and neuronal development in a murine model.
The Journal of biological chemistry 2011;286(1):726-36.
2010: Malia M Edwards; Elmina Mammadova-Bach; Fabien Alpy; Annick Klein; Wanda L Hicks; Michel Roux; Patricia Simon-Assmann; Richard S Smith; Gertraud Orend; Jiang Wu; Neal S Peachey; Jürgen K Naggert; Olivier Lefebvre; Patsy M Nishina
Mutations in Lama1 disrupt retinal vascular development and inner limiting membrane formation.
The Journal of biological chemistry 2010;285(10):7697-711.
2008: Dennis M Maddox; Kirstan A Vessey; Gary L Yarbrough; Brandon M Invergo; Donald R Cantrell; Samsoon Inayat; Victoria Balannik; Wanda L Hicks; Norman L Hawes; Shannon Byers; Richard S Smith; Ronald E Hurd; Douglas Howell; Ronald G Gregg; Bo Chang; Jürgen K Naggert; John B Troy; Lawrence H Pinto; Patsy M Nishina; Maureen A McCall
Allelic variance between GRM6 mutants, Grm6nob3 and Grm6nob4 results in differences in retinal ganglion cell visual responses.
The Journal of physiology 2008;586(Pt 18):4409-24.
2008: Jungyeon Won; Richard S Smith; Neal S Peachey; Jiang Wu; Wanda L Hicks; Jürgen K Naggert; Patsy M Nishina
Membrane frizzled-related protein is necessary for the normal development and maintenance of photoreceptor outer segments.
Visual neuroscience 2008;25(4):563-74.
2007: Gareth R Howell; Richard T Libby; Tatjana C Jakobs; Richard S Smith; F Campbell Phalan; Joseph W Barter; Jessica M Barbay; Jeffrey K Marchant; Nagaraju Mahesh; Vittorio porciatti; Alan V Whitmore; Richard H Masland; Simon W M John
Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma.
The Journal of cell biology 2007;179(7):1523-37.
2007: Douglas B Gould; Jeffrey K Marchant; Olga V Savinova; Richard S Smith; Simon W M John
Col4a1 mutation causes endoplasmic reticulum stress and genetically modifiable ocular dysgenesis.
Human molecular genetics 2007;16(7):798-807.
2007: Richard T Libby; Gareth R Howell; Iok-Hou Pang; Olga V Savinova; Adrienne K Mehalow; Joseph W Barter; Richard S Smith; Abbot F Clark; Simon W M John
Inducible nitric oxide synthase, Nos2, does not mediate optic neuropathy and retinopathy in the DBA/2J glaucoma model.
BMC neuroscience 2007;8():108.
2007: Gareth R Howell; Richard T Libby; Jeffrey K Marchant; Lawriston A Wilson; Ioan M Cosma; Richard S Smith; Michael G Anderson; Simon W M John
Absence of glaucoma in DBA/2J mice homozygous for wild-type versions of Gpnmb and Tyrp1.
BMC genetics 2007;8():45.
2006: Neena B Haider; Paul J DeMarco; Arne M Nystuen; Xiaona Huang; Richard S Smith; Maureen A McCall; Jürgen K Naggert; Patsy M Nishina
The transcription factor Nr2e3 functions in retinal progenitors to suppress cone cell generation.
Visual neuroscience 2006;23(6):917-29.
2006: Douglas B Gould; Mark Reedy; Lawriston A Wilson; Richard S Smith; Randy L Johnson; Simon W M John
Mutant myocilin nonsecretion in vivo is not sufficient to cause glaucoma.
Molecular and cellular biology 2006;26(22):8427-36.
2006: Babette Gwynn; Richard S Smith; Lucy B Rowe; Benjamin A Taylor; Luanne L Peters
A mouse TRAPP-related protein is involved in pigmentation.
Genomics 2006;88(2):196-203.
2006: Bonnie L Lyons; Richard S Smith; Ronald E Hurd; Norman L Hawes; Lisa M Burzenski; Steven Nusinowitz; Muneer G Hasham; Bo Chang; Leonard D Shultz
Deficiency of SHP-1 protein-tyrosine phosphatase in "viable motheaten" mice results in retinal degeneration.
Investigative ophthalmology & visual science 2006;47(3):1201-9.
2006: Michael G Anderson; Richard T Libby; Mao Mao; Ioan M Cosma; Lawriston A Wilson; Richard S Smith; Simon W M John
Genetic context determines susceptibility to intraocular pressure elevation in a mouse pigmentary glaucoma.
BMC biology 2006;4():20.
2005: Yongsuk Lee; Shuhei Kameya; Gregory A Cox; Jennifer Hsu; Wanda Hicks; Terry P Maddatu; Richard S Smith; Jürgen K Naggert; Neal S Peachey; Patsy M Nishina
Ocular abnormalities in Large(myd) and Large(vls) mice, spontaneous models for muscle, eye, and brain diseases.
Molecular and cellular neurosciences 2005;30(2):160-72.
2005: Richard T Libby; Michael G Anderson; Iok-Hou Pang; Zachary H Robinson; Olga V Savinova; Ioan M Cosma; Amy Snow; Lawriston A Wilson; Richard S Smith; Abbot F Clark; Simon W M John
Inherited glaucoma in DBA/2J mice: pertinent disease features for studying the neurodegeneration.
Visual neuroscience 2005;22(5):637-48.
2005: Gayle B Collin; E Cyr; R Bronson; Jan D Marshall; Elaine J Gifford; W Hicks; Stephen A Murray; Qing Yin Zheng; Richard S Smith; Patsy M Nishina; Jürgen K Naggert
Alms1-disrupted mice recapitulate human Alström syndrome.
Human molecular genetics 2005;14(16):2323-33.
2005: Richard T Libby; Yan Li; Olga V Savinova; Joseph Barter; Richard S Smith; Robert W Nickells; Simon W M John
Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage.
PLoS genetics 2005;1(1):17-26.
2005: Douglas B Gould; F Campbell Phalan; Guido J Breedveld; Saskia E van Mil; Richard S Smith; John C Schimenti; Umberto Aguglia; Marjo S van der Knaap; Peter Heutink; Simon W M John
Mutations in Col4a1 cause perinatal cerebral hemorrhage and porencephaly.
Science (New York, N.Y.) 2005;308(5725):1167-71.
2005: Michael G Anderson; Richard T Libby; Douglas B Gould; Richard S Smith; Simon W M John
High-dose radiation with bone marrow transfer prevents neurodegeneration in an inherited glaucoma.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(12):4566-71.
2004: Douglas B Gould; Laura Miceli-Libby; Olga V Savinova; Mario Torrado; Stanislav I Tomarev; Richard S Smith; Simon W M John
Genetically increasing Myoc expression supports a necessary pathologic role of abnormal proteins in glaucoma.
Molecular and cellular biology 2004;24(20):9019-25.
2004: Douglas B Gould; Richard S Smith; Simon W M John
Anterior segment development relevant to glaucoma.
The International journal of developmental biology 2004;48(8-9):1015-29.
2003: Adrienne K Mehalow; Shuhei Kameya; Richard S Smith; Norman L Hawes; James M Denegre; James A Young; Lesley Bechtold; Neena B Haider; Ulrich Tepass; John R Heckenlively; Bo Chang; Jürgen K Naggert; Patsy M Nishina
CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina.
Human molecular genetics 2003;12(17):2179-89.
2003: Jun-Song Mo; Michael G Anderson; Meredith Gregory; Richard S Smith; Olga V Savinova; David V Serreze; Bruce R Ksander; J Wayne Streilein; Simon W M John
By altering ocular immune privilege, bone marrow-derived cells pathogenically contribute to DBA/2J pigmentary glaucoma.
The Journal of experimental medicine 2003;197(10):1335-44.
2003: Sakae Ikeda; Leslie A Cunningham; Dawnalyn Boggess; Norman L Hawes; Craig D Hobson; John P Sundberg; Jürgen K Naggert; Richard S Smith; Patsy M Nishina
Aberrant actin cytoskeleton leads to accelerated proliferation of corneal epithelial cells in mice deficient for destrin (actin depolymerizing factor).
Human molecular genetics 2003;12(9):1029-37.
2003: Richard T Libby; Richard S Smith; Olga V Savinova; Adriana Zabaleta; Janice E Martin; Frank J Gonzalez; Simon W M John
Modification of ocular defects in mouse developmental glaucoma models by tyrosinase.
Science (New York, N.Y.) 2003;299(5612):1578-81.
2002: Kelly A Young; Melissa L Berry; Connie L Mahaffey; Jennifer R Saionz; Norman L Hawes; Bo Chang; Qing Yin Zheng; Richard S Smith; Roderick T Bronson; Randy J Nelson; Elizabeth M Simpson
Fierce: a new mouse deletion of Nr2e1; violent behaviour and ocular abnormalities are background-dependent.
Behavioural brain research 2002;132(2):145-58.
2002: Richard S Smith; Donald Korb; Simon W M John
A goniolens for clinical monitoring of the mouse iridocorneal angle and optic nerve.
Molecular vision 2002;8():26-31.
2002: Richard S Smith; James V Miller; John P Sundberg
Intraocular teratoma in a mouse.
Comparative medicine 2002;52(1):68-72.
2002: Michael G Anderson; Richard S Smith; Norman L Hawes; Adriana Zabaleta; Bo Chang; Janey L Wiggs; Simon W M John
Mutations in genes encoding melanosomal proteins cause pigmentary glaucoma in DBA/2J mice.
Nature genetics 2002;30(1):81-5.
2001: B S Kim; Olga V Savinova; M V Reedy; J Martin; YZ Lun; Lin Gan; Richard S Smith; Stanislav I Tomarev; Simon W M John; Randy L Johnson
Targeted Disruption of the Myocilin Gene (Myoc) Suggests that Human Glaucoma-Causing Mutations Are Gain of Function.
Molecular and cellular biology 2001;21(22):7707-13.
2001: Dieter Näf; Lawriston A Wilson; Rebecca A Bergstrom; Richard S Smith; N C Goodwin; A Verkerk; G J van Ommen ; Susan L Ackerman; Wayne N Frankel; John C Schimenti
Mouse models for the Wolf-Hirschhorn deletion syndrome.
Human molecular genetics 2001;10(2):91-8.
2001: Bo Chang; Richard S Smith; M Peters; Olga V Savinova; Norman L Hawes; Adriana Zabaleta; Steven Nusinowitz; Janice E Martin; M L Davisson; C L Cepko; Brigid L M Hogan; Simon W M John
Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure.
BMC genetics 2001;2():18.
2001: Olga V Savinova; Fumihiro Sugiyama; Janice E Martin; Stanislav I Tomarev; B J Paigen; Richard S Smith; Simon W M John
Intraocular pressure in genetically distinct mice: an update and strain survey.
BMC genetics 2001;2():12.
2001: Richard S Smith; Adriana Zabaleta; Olga V Savinova; Simon W M John
The mouse anterior chamber angle and trabecular meshwork develop without cell death.
BMC developmental biology 2001;1():3.
2001: Michael G Anderson; Richard S Smith; Olga V Savinova; Norman L Hawes; Bo Chang; Adriana Zabaleta; R Wilpan; John R Heckenlively; Muriel T Davisson; Simon W M John
Genetic modification of glaucoma associated phenotypes between AKXD-28/Ty and DBA/2J mice.
BMC genetics 2001;2():1.
2000: Babette Gwynn; Steven L Ciciotte; S J Hunter; Linda L Washburn; Richard S Smith; Sabra G Andersen; Richard T Swank; Esteban C Dell'Angelica; Juan Bonifacino; Eva M Eicher; Luanne L Peters
Defects in the cappuccino (cno) gene on mouse chromosome 5 and human 4p cause Hermansky-Pudlak syndrome by an AP-3-independent mechanism.
Blood 2000;96(13):4227-35.
2000: Norman L Hawes; Bo Chang; G S Hageman; Steven Nusinowitz; Patsy M Nishina; B S Schneider; Richard S Smith; TH Roderick; Muriel T Davisson; John R Heckenlively
Retinal degeneration 6 (rd6): a new mouse model for human retinitis punctata albescens.
Investigative ophthalmology & visual science 2000;41(10):3149-57.
2000: Richard S Smith; Adriana Zabaleta; T Kume; Olga V Savinova; Susan H Kidson; Janice E Martin; Darryl Y Nishimura; Wallace L M Alward; Brigid L M Hogan; Simon W M John
Haploinsufficiency of the transcription factors FOXC1 and FOXC2 results in aberrant ocular development.
Human molecular genetics 2000;9(7):1021-32.
2000: Richard S Smith; Simon W M John; A Zabeleta; Muriel T Davisson; Norman L Hawes; Bo Chang
The bst locus on mouse chromosome 16 is associated with age-related subretinal neovascularization.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(5):2191-5.
2000: Richard S Smith; Norman L Hawes; Bo Chang; TH Roderick; Ellen C Akeson; John R Heckenlively; X Gong; X Wang; Muriel T Davisson
Lop12, a mutation in mouse Crygd causing lens opacity similar to human Coppock cataract.
Genomics 2000;63(3):314-20.
2000: Sakae Ikeda; N Shiva; Akihiro Ikeda; Richard S Smith; Steven Nusinowitz; G Yan; T R Lin; S Chu; John R Heckenlively; M A North; Jürgen K Naggert; Patsy M Nishina; M P Duyao
Retinal degeneration but not obesity is observed in null mutants of the tubby-like protein 1 gene.
Human molecular genetics 2000;9(2):155-63.
1999: Simon W M John; Michael G Anderson; Richard S Smith
Mouse genetics: a tool to help unlock the mechanisms of glaucoma.
Journal of glaucoma 1999;8(6):400-12.
1999: Norman L Hawes; Richard S Smith; Bo Chang; Muriel T Davisson; John R Heckenlively; Simon W M John
Mouse fundus photography and angiography: a catalogue of normal and mutant phenotypes.
Molecular vision 1999;5():22.
1999: Bo Chang; Norman L Hawes; TH Roderick; Richard S Smith; John R Heckenlively; J Horwitz; Muriel T Davisson
Identification of a missense mutation in the alphaA-crystallin gene of the lop18 mouse.
Molecular vision 1999;5():21.
1999: S Ikeda; Norman L Hawes; Bo Chang; C S Avery; Richard S Smith; Patsy M Nishina
Severe ocular abnormalities in C57BL/6 but not in 129/Sv p53-deficient mice.
Investigative ophthalmology & visual science 1999;40(8):1874-8.
1999: Bo Chang; Richard S Smith; Norman L Hawes; Michael G Anderson; Adriana Zabaleta; Olga V Savinova; TH Roderick; John R Heckenlively; Muriel T Davisson; Simon W M John
Interacting loci cause severe iris atrophy and glaucoma in DBA/2J mice.
Nature genetics 1999;21(4):405-9.
1998: Simon W M John; Richard S Smith; Olga V Savinova; Norman L Hawes; Bo Chang; Daniel Turnbull; Muriel T Davisson; TH Roderick; John R Heckenlively
Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice.
Investigative ophthalmology & visual science 1998;39(6):951-62.
1996: Bo Chang; Norman L Hawes; Richard S Smith; John R Heckenlively; Muriel T Davisson; TH Roderick
Chromosomal localization of a new mouse lens opacity gene (lop18)
Genomics 1996;36(1):171-3.
1996: Richard S Smith; Norman L Hawes; S D Kuhlmann; John R Heckenlively; Bo Chang; TH Roderick; J P Sundberg
Corn1: a mouse model for corneal surface disease and neovascularization.
Investigative ophthalmology & visual science 1996;37(2):397-404.