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Oliver Smithies

Research Profile

Living Beings

Chemicals & Drugs

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Blood Pressure

Genes & Molecular Sequences

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Recombination, Genetic

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TOP 3
Masao Kakoki; Yukako Kayashima; Hyung-Suk Kim; Feng Li; Mykola Mamenko; Kota Matsuki; Oleh Pochynyuk; Alejandro M Bertorello; Ruriko Grant; John R Hagaman; Catherine M Hathaway; S Hiller; Hirofumi Tomita; Longquan Xu; Oleg L Zaika; Oliver Smithies
Primary aldosteronism and impaired natriuresis in mice underexpressing TGFβ1.
Hirofumi Tomita; Ryan B Sanford; Oliver Smithies; Masao Kakoki
The kallikrein-kinin system in diabetic nephropathy.
Kumar Pandya; Youichiro Wada; Mika Kobayashi; Tatsuhiko Kodama; Takahide Kohro; Imari Mimura; Oliver Smithies
Distribution of histone3 lysine 4 trimethylation at T3-responsive loci in the heart during reversible changes in gene expression.

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All Publications

2013: Masao Kakoki; Yukako Kayashima; Hyung-Suk Kim; Feng Li; Mykola Mamenko; Kota Matsuki; Oleh Pochynyuk; Alejandro M Bertorello; Ruriko Grant; John R Hagaman; Catherine M Hathaway; S Hiller; Hirofumi Tomita; Longquan Xu; Oleg L Zaika; Oliver Smithies
Primary aldosteronism and impaired natriuresis in mice underexpressing TGFβ1.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(14):5600-5.
2012: Hirofumi Tomita; Ryan B Sanford; Oliver Smithies; Masao Kakoki
The kallikrein-kinin system in diabetic nephropathy.
Kidney international 2012;81(8):733-44.
2012: Kumar Pandya; Youichiro Wada; Mika Kobayashi; Tatsuhiko Kodama; Takahide Kohro; Imari Mimura; Oliver Smithies
Distribution of histone3 lysine 4 trimethylation at T3-responsive loci in the heart during reversible changes in gene expression.
Gene expression 2012;15(4):183-98.
2012: Oliver Smithies
How it all began: a personal history of gel electrophoresis.
Methods in molecular biology (Clifton, N.J.) 2012;869():1-21.
2012: Yukako Kayashima; Oliver Smithies; Masao Kakoki
The kallikrein-kinin system and oxidative stress.
Current opinion in nephrology and hypertension 2012;21(1):92-6.
2011: Kumar Pandya; Oliver Smithies
β-MyHC and cardiac hypertrophy: size does matter.
Circulation research 2011;109(6):609-10.
2011: Raymond Fox; Hyung-Suk Kim; Robert L Reddick; Gregory C Kujoth; Tomas A Prolla; Shuichi Tsutsumi; Youichiro Wada; Oliver Smithies; Nobuyo Maeda
Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(21):8779-84.
2011: Seigo Hatada; William Walton; Tomoko Hatada; Anne Wofford; Raymond Fox; Naiyou Liu; Michael C Lill; Jeffrey Fair; Suzanne L Kirby; Oliver Smithies
Therapeutic benefits in thalassemic mice transplanted with long-term-cultured bone marrow cells.
Experimental hematology 2011;39(3):375-83, 383.e1-4.
2011: Chih-Hong Wang; Feng Li; S Hiller; Hyung-Suk Kim; Nobuyo Maeda; Oliver Smithies; Nobuyuki Takahashi
A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(5):2070-5.
2010: Tetsuo Konno; Dan Chen; Libin Wang; Hiroko Wakimoto; Polakit Teekakirikul; Matthew Nayor; Masataka Kawana; Seda Eminaga; Joshua M Gorham; Kumar Pandya; Oliver Smithies; Francisco J Naya; Eric N Olson; Jonathan G Seidman; Christine E Seidman
Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(42):18097-102.
2010: Masao Kakoki; Kelli A Sullivan; Carey Backus; John M Hayes; Sang Su Oh; Kunjie Hua; Adil M H Gasim; Hirofumi Tomita; Ruriko Grant; Sarah B Nossov; Hyung-Suk Kim; J Charles Jennette; Eva L Feldman; Oliver Smithies
Lack of both bradykinin B1 and B2 receptors enhances nephropathy, neuropathy, and bone mineral loss in Akita diabetic mice.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(22):10190-5.
2010: Kumar Pandya; Benjamin Pulli; Scott Bultman; Oliver Smithies
Reversible epigenetic modifications of the two cardiac myosin heavy chain genes during changes in expression.
Gene expression 2010;15(2):51-9.
2009: Nicola J A Scott; Leigh J Ellmers; John G Lainchbury; Nobuyo Maeda; Oliver Smithies; A Mark Richards; Vicky A Cameron
Influence of natriuretic peptide receptor-1 on survival and cardiac hypertrophy during development.
Biochimica et biophysica acta 2009;1792(12):1175-84.
2009: Frank C Brosius III; Charles E Alpers; Erwin P Bottinger; Matthew D Breyer; Thomas M Coffman; Susan B Gurley; Raymond C Harris; Masao Kakoki; Matthias Kretzler; Edward H Leiter; Moshe Levi; McIndoe Richard; Kumar Sharma; Oliver Smithies; Katalin Susztak; Nobuyuki Takahashi; Takamune Takahashi
Mouse models of diabetic nephropathy.
Journal of the American Society of Nephrology : JASN 2009;20(12):2503-12.
2009: Yau-Sheng Tsai; Lonquan Xu; Oliver Smithies; Nobuyo Maeda
Genetic variations in peroxisome proliferator-activated receptor gamma expression affect blood pressure.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(45):19084-9.
2009: Kumar Pandya; Kristine Porter; Howard A Rockman; Oliver Smithies
Decreased beta-adrenergic responsiveness following hypertrophy occurs only in cardiomyocytes that also re-express beta-myosin heavy chain.
European journal of heart failure 2009;11(7):648-52.
2009: Masao Kakoki; Oliver Smithies
The kallikrein-kinin system in health and in diseases of the kidney.
Kidney international 2009;75(10):1019-30.
2009: Saovaros Svasti; Thipparat Suwanmanee; Suthat Fucharoen; Hong M Moulton; Michelle H Nelson; Nobuyo Maeda; Oliver Smithies; Ryszard Kole
RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(4):1205-10.
2009: Anne-Cécile Huby; Maria Pia Rastaldi; Kathleen M Caron; Oliver Smithies; Jean-Claude Dussaule; Christos Chatziantoniou
Restoration of podocyte structure and improvement of chronic renal disease in transgenic mice overexpressing renin.
PloS one 2009;4(8):e6721.
2009: Jessica Epple-Farmer; Bisrat Debeb; Oliver Smithies; Bert Binas
Gender-dependent survival of allogeneic trophoblast stem cells in liver.
Cell transplantation 2009;18(7):769-76.
2008: Kumar Pandya; John Cowhig; Joe Brackhan; Hyung-Suk Kim; John R Hagaman; Mauricio Rojas; Charles Carter; Lan Mao; Howard A Rockman; Nobuyo Maeda; Oliver Smithies
Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(35):13063-8.
2008: Oliver Smithies
Tea with Dr Oliver Smithies, 2007 Nobel laureate in physiology and medicine. Interview by Dr. Anthony Viera.
Journal of clinical hypertension (Greenwich, Conn.) 2008;10(8):640-3.
2008: Oliver Smithies
Turning pages (Nobel lecture).
Chembiochem : a European journal of chemical biology 2008;9(9):1342-59.
2008: K Bridget Brosnihan; Jeffrey B Hodgin; Oliver Smithies; Nobuyo Maeda; Patricia Gallagher
Tissue-specific regulation of ACE/ACE2 and AT1/AT2 receptor gene expression by oestrogen in apolipoprotein E/oestrogen receptor-alpha knock-out mice.
Experimental physiology 2008;93(5):658-64.
2008: Natalia Makhanova; John R Hagaman; Hyung-Suk Kim; Oliver Smithies
Salt-sensitive blood pressure in mice with increased expression of aldosterone synthase.
Hypertension 2008;51(1):134-40.
2007: Zeenat S Hakim; Laura A DiMichele; Jason T Doherty; Jonathon W Homeister; Hilary E Beggs; Louis F Reichardt; Robert J Schwartz; Joseph Brackhan; Oliver Smithies; Christopher P Mack; Joan M Taylor
Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment.
Molecular and cellular biology 2007;27(15):5352-64.
2007: Ryan Dackor; Kimberly L Fritz-Six; Oliver Smithies; Kathleen M Caron
Receptor activity-modifying proteins 2 and 3 have distinct physiological functions from embryogenesis to old age.
The Journal of biological chemistry 2007;282(25):18094-9.
2007: Masao Kakoki; Robert W McGarrah; Hyung-Suk Kim; Oliver Smithies
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(18):7576-81.
2007: Naohiro Yamaguchi; Nobuyuki Takahashi; Le Xu; Oliver Smithies; Gerhard Meissner
Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca release channel.
The Journal of clinical investigation 2007;117(5):1344-53.
2007: Kathleen M Caron; John Hagaman; Toshio Nishikimi; Hyung-Suk Kim; Oliver Smithies
Adrenomedullin gene expression differences in mice do not affect blood pressure but modulate hypertension-induced pathology in males.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3420-5.
2007: Leigh J Ellmers; Nicola J A Scott; Jarkko Piuhola; Nobuyo Maeda; Oliver Smithies; Christopher M Frampton; A Mark Richards; Vicky A Cameron
Npr1-regulated gene pathways contributing to cardiac hypertrophy and fibrosis.
Journal of molecular endocrinology 2007;38(1-2):245-57.
2006: Natalia Makhanova; Maria Luisa S Sequeira Lopez; R Ariel Gomez; Hyung-Suk Kim; Oliver Smithies
Disturbed homeostasis in sodium-restricted mice heterozygous and homozygous for aldosterone synthase gene disruption.
Hypertension 2006;48(6):1151-9.
2006: Steven D Crowley; Susan B Gurley; Maria J Herrera; Phillip Ruiz; Robert Griffiths; Anil P Kumar; Hyung-Suk Kim; Oliver Smithies; Thu H Le; Thomas M Coffman
Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(47):17985-90.
2006: Kumar Pandya; Hyung-Suk Kim; Oliver Smithies
Fibrosis, not cell size, delineates beta-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(45):16864-9.
2006: Manyu Li; Della Yee; Terry Magnuson; Oliver Smithies; Kathleen M Caron
Reduced maternal expression of adrenomedullin disrupts fertility, placentation, and fetal growth in mice.
The Journal of clinical investigation 2006;116(10):2653-62.
2006: Osamu Yasuda; Keisuke Fukuo; Xin Sun; Masahito Nishitani; Takamori Yotsui; Masayoshi Higuchi; Takashi Suzuki; Hiromi Rakugi; Oliver Smithies; Nobuyo Maeda; Toshio Ogihara
Apop-1, a novel protein inducing cyclophilin D-dependent but Bax/Bak-related channel-independent apoptosis.
The Journal of biological chemistry 2006;281(33):23899-907.
2006: Masao Kakoki; Hyung-Suk Kim; Cora-Jean S Edgell; Nobuyo Maeda; Oliver Smithies; David L Mattson
Amino acids as modulators of endothelium-derived nitric oxide.
American journal of physiology. Renal physiology 2006;291(2):F297-304.
2006: Dominic Ciavatta; Sundeep Kalantry; Terry Magnuson; Oliver Smithies
A DNA insulator prevents repression of a targeted X-linked transgene but not its random or imprinted X inactivation.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(26):9958-63.
2006: Cinzia Perrino; Sathyamangla V Naga Prasad; Lan Mao; Takahisa Noma; Zhen Yan; Hyung-Suk Kim; Oliver Smithies; Howard A Rockman
Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction.
The Journal of clinical investigation 2006;116(6):1547-60.
2006: Masao Kakoki; Catherine M Kizer; Xianwen Yi; Nobuyuki Takahashi; Hyung-Suk Kim; Charles Bagnell; Cora-Jean S Edgell; Nobuyo Maeda; John Jennette; Oliver Smithies
Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors.
The Journal of clinical investigation 2006;116(5):1302-9.
2006: Ryan Dackor; Kimberly L Fritz-Six; William P Dunworth; Carrie L Gibbons; Oliver Smithies; Kathleen M Caron
Hydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the calcitonin receptor-like receptor gene.
Molecular and cellular biology 2006;26(7):2511-8.
2006: Natalia Makhanova; Gene Lee; Nobuyuki Takahashi; Maria Luisa S Sequeira Lopez; R Ariel Gomez; Hyung-Suk Kim; Oliver Smithies
Kidney function in mice lacking aldosterone.
American journal of physiology. Renal physiology 2006;290(1):F61-9.
2005: Seigo Hatada; LW Arnold; Tomoko Hatada; John E Cowhig; Dominic Ciavatta; Oliver Smithies
Isolating gene-corrected stem cells without drug selection.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(45):16357-61.
2005: John R Hagaman; Simon John; Lonquan Xu; Oliver Smithies; Nobuyo Maeda
An improved technique for tail-cuff blood pressure measurements with dark-tailed mice.
Contemporary topics in laboratory animal science / American Association for Laboratory Animal Science 2005;44(5):43-6.
2005: Gene Lee; Natalia Makhanova; Kathleen M Caron; Maria Luisa S Sequeira Lopez; R Ariel Gomez; Oliver Smithies; Hyung-Suk Kim
Homeostatic responses in the adrenal cortex to the absence of aldosterone in mice.
Endocrinology 2005;146(6):2650-6.
2005: Oliver Smithies
An interview with... Oliver Smithies [interviewed by Magdalena Skipper].
Nature reviews. Genetics 2005;6(5):350.
2005: Oliver Smithies
Many little things: one geneticist's view of complex diseases.
Nature reviews. Genetics 2005;6(5):419-25.
2005: Steven D Crowley; Susan B Gurley; Michael I Oliverio; A Kathy Pazmino; Robert Griffiths; Patrick J Flannery; Robert F Spurney; Hyung-Suk Kim; Oliver Smithies; Thu H Le; Thomas M Coffman
Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system.
The Journal of clinical investigation 2005;115(4):1092-9.
2005: Toshio Nishikimi; John R Hagaman; Nobuyuki Takahashi; Hyung-Suk Kim; Hiroaki Matsuoka; Oliver Smithies; Nobuyo Maeda
Increased susceptibility to heart failure in response to volume overload in mice lacking natriuretic peptide receptor-A gene.
Cardiovascular research 2005;66(1):94-103.
2005: Jeffrey Fair; Bruce A Cairns; Michael Lapaglia; Montserrat Caballero; W Andrew Pleasant; Seigo Hatada; Hyung-Suk Kim; Tong Gui; Larysa Pevny; Anthony A Meyer; Darrel W Stafford; Oliver Smithies; Jeffrey Frelinger
Correction of factor IX deficiency in mice by embryonic stem cells differentiated in vitro.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(8):2958-63.
2005: Kathleen M Caron; Leighton R James; Gene Lee; Hyung-Suk Kim; Oliver Smithies
Lifelong genetic minipumps.
Physiological genomics 2005;20(2):203-9.
2005: Nobuyuki Takahashi; Maria Luisa S Sequeira Lopez; John E Cowhig; Melissa A Taylor; Tomoko Hatada; Emily Riggs; Gene Lee; R Ariel Gomez; Hyung-Suk Kim; Oliver Smithies
Ren1c homozygous null mice are hypotensive and polyuric, but heterozygotes are indistinguishable from wild-type.
Journal of the American Society of Nephrology : JASN 2005;16(1):125-32.
2004: Masao Kakoki; Nobuyuki Takahashi; John Jennette; Oliver Smithies
Diabetic nephropathy is markedly enhanced in mice lacking the bradykinin B2 receptor.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(36):13302-5.
2004: Stephanie M Cohen; Seigo Hatada; Bruna P Brylawski; Oliver Smithies; David G Kaufman; Marila Cordeiro-Stone
Complementation of replication origin function in mouse embryonic stem cells by human DNA sequences.
Genomics 2004;84(3):475-84.
2004: Yi Jiang; Kumar Pandya; Oliver Smithies; Edward W Hsu
Three-dimensional diffusion tensor microscopy of fixed mouse hearts.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2004;52(3):453-60.
2004: Thu H Le; Michael I Oliverio; Hyung-Suk Kim; Harmony R Salzler; Rajesh C Dash; David N Howell; Oliver Smithies; Sarah Bronson; Thomas M Coffman
A gammaGT-AT1A receptor transgene protects renal cortical structure in AT1 receptor-deficient mice.
Physiological genomics 2004;18(3):290-8.
2004: Jennifer L Goulet; Amy J Pace; Mikelle Key-Solle; Robert S Byrum; MyTrang Nguyen; Stephen L Tilley; Scott G Morham; Robert Langenbach; Jeffrey L Stock; John McNeish; Oliver Smithies; Thomas M Coffman; Beverly H Koller
E-prostanoid-3 receptors mediate the proinflammatory actions of prostaglandin E2 in acute cutaneous inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):1321-6.
2004: Maria Luisa S Sequeira López; Ellen Steward Pentz; Takayo Nomasa; Oliver Smithies; R Ariel Gomez
Renin cells are precursors for multiple cell types that switch to the renin phenotype when homeostasis is threatened.
Developmental cell 2004;6(5):719-28.
2004: Masao Kakoki; Yau-Sheng Tsai; Hyung-Suk Kim; Seigo Hatada; Dominic Ciavatta; Nobuyuki Takahashi; LW Arnold; Nobuyo Maeda; Oliver Smithies
Altering the expression in mice of genes by modifying their 3' regions.
Developmental cell 2004;6(4):597-606.
2004: Kathleen M Caron; Leighton R James; Hyung-Suk Kim; Josh Knowles; Rick Uhlir; Lan Mao; John R Hagaman; Wayne E Cascio; Howard A Rockman; Oliver Smithies
Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(9):3106-11.
2004: Nobuyuki Takahashi; Oliver Smithies
Human genetics, animal models and computer simulations for studying hypertension.
Trends in genetics : TIG 2004;20(3):136-45.
2003: Thu H Le; Hyung-Suk Kim; Andrew M Allen; Robert F Spurney; Oliver Smithies; Thomas M Coffman
Physiological impact of increased expression of the AT1 angiotensin receptor.
Hypertension 2003;42(4):507-14.
2003: Shang-Jin Shi; Elangovan Vellaichamy; So Yeon Chin; Oliver Smithies; L Gabriel Navar; Kailash N Pandey
Natriuretic peptide receptor A mediates renal sodium excretory responses to blood volume expansion.
American journal of physiology. Renal physiology 2003;285(4):F694-702.
2003: Joan Garey; Andrew Goodwillie; Jonathan Frohlich; Maria Morgan; Jan-�ke GUSTAFSSON; Oliver Smithies; Kenneth S Korach; Sonoko Ogawa; Donald Pfaff
Genetic contributions to generalized arousal of brain and behavior.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(19):11019-22.
2003: Jeffrey Fair; Bruce A Cairns; Michael Lapaglia; Jian Wang; Anthony A Meyer; Hyung-Suk Kim; Seigo Hatada; Oliver Smithies; Larysa Pevny
Induction of hepatic differentiation in embryonic stem cells by co-culture with embryonic cardiac mesoderm.
Surgery 2003;134(2):189-96.
2003: Nobuyuki Takahashi; John R Hagaman; Hyung-Suk Kim; Oliver Smithies
Minireview: computer simulations of blood pressure regulation by the renin-angiotensin system.
Endocrinology 2003;144(6):2184-90.
2003: Oliver Smithies
Why the kidney glomerulus does not clog: a gel permeation/diffusion hypothesis of renal function.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):4108-13.
2002: Kathleen E McDougall; Mark J Perry; Rachel L Gibson; J M Bright; Shane M Colley; Jeffrey B Hodgin; Oliver Smithies; Jonathan H Tobias
Estrogen-induced osteogenesis in intact female mice lacking ERbeta.
American journal of physiology. Endocrinology and metabolism 2002;283(4):E817-23.
2002: Eun-Hee Shim; Jong-Il Kim; Eui-Suk Bang; Jun-Seok Heo; Jae-Seon Lee; Eun-Young Kim; Jong-Eun Lee; Woong-Yang Park; Soon-Hee Kim; Hyung-Suk Kim; Oliver Smithies; Ja-Joon Jang; Dong-Il Jin; Jeong-Sun Seo
Targeted disruption of hsp70.1 sensitizes to osmotic stress.
EMBO reports 2002;3(9):857-61.
2002: Leigh J Ellmers; J W Knowles; H-S Kim; Oliver Smithies; Nobuyo Maeda; Vicky A Cameron
Ventricular expression of natriuretic peptides in Npr1(-/-) mice with cardiac hypertrophy and fibrosis.
American journal of physiology. Heart and circulatory physiology 2002;283(2):H707-14.
2002: Kathleen M Caron; Leighton R James; Hyung-Suk Kim; Scott G Morham; Maria Luisa S Sequeira Lopez; R Ariel Gomez; Timothy L Reudelhuber; Oliver Smithies
A genetically clamped renin transgene for the induction of hypertension.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):8248-52.
2002: Masayoshi Nomura; Larissa Durbak; Johnny Chan; Oliver Smithies; Jan-�ke GUSTAFSSON; Kenneth S Korach; Donald Pfaff; Sonoko Ogawa
Genotype/age interactions on aggressive behavior in gonadally intact estrogen receptor beta knockout (betaERKO) male mice.
Hormones and behavior 2002;41(3):288-96.
2002: Hyung-Suk Kim; Gene Lee; Simon W M John; Nobuyo Maeda; Oliver Smithies
Molecular phenotyping for analyzing subtle genetic effects in mice: application to an angiotensinogen gene titration.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4602-7.
2002: Kathleen M Caron; Oliver Smithies
Multiple roles of adrenomedullin revealed by animal models.
Microscopy research and technique 2002;57(1):55-9.
2002: Yasuhiko Makino; Donald N Cook; Oliver Smithies; Olivia Y Hwang; Eric G Neilson; Laurence A Turka; Hiroshi Sato; Andrew D Wells; Theodore M Danoff
Impaired T cell function in RANTES-deficient mice.
Clinical immunology (Orlando, Fla.) 2002;102(3):302-9.
2002: Nobuyuki Takahashi; Heddwen L Brooks; James B Wade; Wen Liu; Yoshiaki Kondo; Sadayoshi Ito; Mark A Knepper; Oliver Smithies
Posttranscriptional compensation for heterozygous disruption of the kidney-specific NaK2Cl cotransporter gene.
Journal of the American Society of Nephrology : JASN 2002;13(3):604-10.
2002: Jeffrey B Hodgin; Joshua W Knowles; Hyung-Suk Kim; Oliver Smithies; Nobuyo Maeda
Interactions between endothelial nitric oxide synthase and sex hormones in vascular protection in mice.
The Journal of clinical investigation 2002;109(4):541-8.
2002: Yan Zhu; Zhao Bian; Ping Lu; Richard H Karas; Lin Bao; Daniel Cox; Jeffrey B Hodgin; Philip W Shaul; Peter Thoren; Oliver Smithies; Jan-�ke GUSTAFSSON; Michael Mendelsohn
Abnormal vascular function and hypertension in mice deficient in estrogen receptor beta.
Science (New York, N.Y.) 2002;295(5554):505-8.
2002: James R Klinger; Rod R Warburton; Linda Pietras; Paula Oliver; Jennifer Fox; Oliver Smithies; Nicholas S Hill
Targeted disruption of the gene for natriuretic peptide receptor-A worsens hypoxia-induced cardiac hypertrophy.
American journal of physiology. Heart and circulatory physiology 2002;282(1):H58-65.
2001: Krairerk Athirakul; Hyung-Suk Kim; Laurent P Audoly; Oliver Smithies; Thomas M Coffman
Deficiency of COX-1 causes natriuresis and enhanced sensitivity to ACE inhibition.
Kidney international 2001;60(6):2324-9.
2001: Miriam E Gerlofs-Nijland; Karel J M Assmann; Henry B P M Dijkman; Jurgen Dieker; Jacco P H F van Son; Stef Mentzel; Jorge P van Kats; Alexander Hessel Jan Danser; Oliver Smithies; Patricia J T A Groenen; Jack F M Wetzels
Albuminuria in mice after injection of antibodies against aminopeptidase A: role of angiotensin II.
Journal of the American Society of Nephrology : JASN 2001;12(12):2711-20.
2001: W Huang; Yves Gallois; Nadine Bouby; Patrick Bruneval; Didier Heudes; Marie-France Belair; John Krege; Pierre Meneton; Michel Marre; Oliver Smithies; François Alhenc-Gelas
Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):13330-4.
2001: Oliver Smithies
Forty years with homologous recombination.
Nature medicine 2001;7(10):1083-6.
2001: R C Gilmore; J Baker; S Dempsey; R Marchan; R N Corprew; G Byrd; Nobuyo Maeda; Oliver Smithies; Richard D Bukoski; Ken R Harewood; Pradeep K Chatterjee
Using PAC nested deletions to order contigs and microsatellite markers at the high repetitive sequence containing Npr3 gene locus.
Gene 2001;275(1):65-72.
2001: Michael F Goy; Paula M Oliver; K E Purdy; Joshua W Knowles; JE Fox; P J Mohler; X Qian; Oliver Smithies; Nobuyo Maeda
Evidence for a novel natriuretic peptide receptor that prefers brain natriuretic peptide over atrial natriuretic peptide.
The Biochemical journal 2001;358(Pt 2):379-87.
2001: Ellen Steward Pentz; Maria Luisa S Sequeira Lopez; Hyung-Suk Kim; Oscar Carretero; Oliver Smithies; R Ariel Gomez
Ren1d and Ren2 cooperate to preserve homeostasis: evidence from mice expressing GFP in place of Ren1d.
Physiological genomics 2001;6(1):45-55.
2001: Joshua W Knowles; G Esposito; L Mao; John R Hagaman; JE Fox; Oliver Smithies; Howard A Rockman; Nobuyo Maeda
Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice.
The Journal of clinical investigation 2001;107(8):975-84.
2001: Jeffrey B Hodgin; John Krege; Robert L Reddick; Kenneth S Korach; Oliver Smithies; Nobuyo Maeda
Estrogen receptor alpha is a major mediator of 17beta-estradiol's atheroprotective effects on lesion size in Apoe-/- mice.
The Journal of clinical investigation 2001;107(3):333-40.
2001: Charles D Loftin; Darshini B Trivedi; Howard F Tiano; J A Clark; Christopher A Lee; J A Epstein; Scott G Morham; Matthew D Breyer; M Nguyen; B M Hawkins; J L Goulet; Oliver Smithies; Beverly H Koller; Robert Langenbach
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(3):1059-64.
2001: Kathleen M Caron; Oliver Smithies
Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(2):615-9.
2000: Sonoko Ogawa; A E Chester; Sylvia Curtis Hewitt; Vickie R Walker; Jan-�ke GUSTAFSSON; Oliver Smithies; Kenneth S Korach; Donald Pfaff
Abolition of male sexual behaviors in mice lacking estrogen receptors alpha and beta (alpha beta ERKO).
Proceedings of the National Academy of Sciences of the United States of America 2000;97(26):14737-41.
2000: Seigo Hatada; K Nikkuni; Stuart Bentley; Suzanne L Kirby; Oliver Smithies
Gene correction in hematopoietic progenitor cells by homologous recombination.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(25):13807-11.
2000: Victoria F Norwood; S G Morham; Oliver Smithies
Postnatal development and progression of renal dysplasia in cyclooxygenase-2 null mice.
Kidney international 2000;58(6):2291-300.
2000: Oliver Smithies; Hyung-Suk Kim; Nobuyuki Takahashi; Marshall Hall Edgell
Importance of quantitative genetic variations in the etiology of hypertension.
Kidney international 2000;58(6):2265-80.
2000: Patricia C Chulada; M B Thompson; JF Mahler; C M Doyle; B W Gaul; C Lee; Howard F Tiano; Scott G Morham; Oliver Smithies; Robert Langenbach
Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice.
Cancer research 2000;60(17):4705-8.
2000: Suzanne L Kirby; W Walton; Oliver Smithies
Hematopoietic stem cells with controllable tEpoR transgenes have a competitive advantage in bone marrow transplantation.
Blood 2000;95(12):3710-5.
2000: Nobuyuki Takahashi; Daniel R Chernavvsky; R Ariel Gomez; P Igarashi; H J Gitelman; Oliver Smithies
Uncompensated polyuria in a mouse model of Bartter's syndrome.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5434-9.
2000: Olivier Morteau; Scott G Morham; Rance K Sellon; Levinus A Dieleman; Robert Langenbach; Oliver Smithies; Ryan Sartor
Impaired mucosal defense to acute colonic injury in mice lacking cyclooxygenase-1 or cyclooxygenase-2.
The Journal of clinical investigation 2000;105(4):469-78.
2000: J W Knowles; Robert L Reddick; John Jennette; Edward Shesely; Oliver Smithies; Nobuyo Maeda
Enhanced atherosclerosis and kidney dysfunction in eNOS(-/-)Apoe(-/-) mice are ameliorated by enalapril treatment.
The Journal of clinical investigation 2000;105(4):451-8.
2000: Michael I Oliverio; CF Best; Oliver Smithies; Thomas M Coffman
Regulation of sodium balance and blood pressure by the AT(1A) receptor for angiotensin II.
Hypertension 2000;35(2):550-4.
2000: Michael I Oliverio; M Delnomdedieu; CF Best; P Li; Mariana Morris; M F Callahan; G Allan Johnson; Oliver Smithies; Thomas M Coffman
Abnormal water metabolism in mice lacking the type 1A receptor for ANG II.
American journal of physiology. Renal physiology 2000;278(1):F75-82.
1999: Richard H Karas; Jeffrey B Hodgin; M Kwoun; John Krege; Mark Aronovitz; William C Mackey; Jan-�ke GUSTAFSSON; Kenneth S Korach; Oliver Smithies; Michael Mendelsohn
Estrogen inhibits the vascular injury response in estrogen receptor beta-deficient female mice.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):15133-6.
1999: Chandra Nataraj; Michael I Oliverio; Roslyn B Mannon; PJ Mannon; Laurent P Audoly; C S Amuchastegui; Phillip Ruiz; Oliver Smithies; Thomas M Coffman
Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway.
The Journal of clinical investigation 1999;104(12):1693-701.
1999: Kailash N Pandey; Paula M Oliver; Nobuyo Maeda; Oliver Smithies
Hypertension associated with decreased testosterone levels in natriuretic peptide receptor-A gene-knockout and gene-duplicated mutant mouse models.
Endocrinology 1999;140(11):5112-9.
1999: Nobuyuki Takahashi; Oliver Smithies
Gene targeting approaches to analyzing hypertension.
Journal of the American Society of Nephrology : JASN 1999;10(7):1598-605.
1999: N Matsukawa; Wojciech J Grzesik; Nobuyuki Takahashi; K N Pandey; S Pang; Mitsuo Yamauchi; Oliver Smithies
The natriuretic peptide clearance receptor locally modulates the physiological effects of the natriuretic peptide system.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7403-8.
1999: Hyung-Suk Kim; Nobuyo Maeda; G T Oh; Lucas Guillermo Fernandez; R Ariel Gomez; Oliver Smithies
Homeostasis in mice with genetically decreased angiotensinogen is primarily by an increased number of renin-producing cells.
The Journal of biological chemistry 1999;274(20):14210-7.
1999: Tim R Traynor; Tianxin Yang; Yuning G Huang; John Krege; Josephine Briggs; Oliver Smithies; Jurgen Schnermann
Tubuloglomerular feedback in ACE-deficient mice.
The American journal of physiology 1999;276(5 Pt 2):F751-7.
1999: James R Klinger; Rod R Warburton; Linda Pietras; Oliver Smithies; R Swift; Nicholas S Hill
Genetic disruption of atrial natriuretic peptide causes pulmonary hypertension in normoxic and hypoxic mice.
The American journal of physiology 1999;276(5 Pt 1):L868-74.
1999: Donald N Cook; Oliver Smithies; R M Strieter; Jeffrey Frelinger; Jonathan S Serody
CD8+ T cells are a biologically relevant source of macrophage inflammatory protein-1 alpha in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(9):5423-8.
1999: Seigo Hatada; William Kuziel; Oliver Smithies; Nobuyo Maeda
The influence of chromosomal location on the expression of two transgenes in mice.
The Journal of biological chemistry 1999;274(2):948-55.
1999: Oliver Smithies
Alexander George Ogston: 30 January 1911-29 June 1996.
Biographical memoirs of fellows of the Royal Society. Royal Society (Great Britain) 1999;45():351-64.
1999: Oliver Smithies
Quantitative genetic variations and essential hypertension.
Harvey lectures 1999;95():1-20.
1999: R J Fern; C M Yesko; Barbara A Thornhill; Hyo-Soo Kim; Oliver Smithies; Robert L Chevalier
Reduced angiotensinogen expression attenuates renal interstitial fibrosis in obstructive nephropathy in mice.
The Journal of clinical investigation 1999;103(1):39-46.
1998: John Krege; Jeffrey B Hodgin; John F Couse; E Enmark; M Warner; J F Mahler; M Sar; Kenneth S Korach; Jan-�ke GUSTAFSSON; Oliver Smithies
Generation and reproductive phenotypes of mice lacking estrogen receptor beta.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15677-82.
1998: Michael I Oliverio; Hyung-Suk Kim; M Ito; T Le; Laurent P Audoly; CF Best; S Hiller; Kimberly D Kluckman; Nobuyo Maeda; Oliver Smithies; Thomas M Coffman
Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15496-501.
1998: Dennis W Thomas; Roslyn B Mannon; PJ Mannon; Anne M Latour; J A Oliver; Maureane Hoffman; Oliver Smithies; Beverly H Koller; Thomas M Coffman
Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2.
The Journal of clinical investigation 1998;102(11):1994-2001.
1998: Randy J Thresher; Martha Hotz Vitaterna; Y Miyamoto; A Kazantsev; DS Hsu; C Petit; Christopher P Selby; L Dawut; Oliver Smithies; Joseph S Takahashi; Aziz Sancar
Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses.
Science (New York, N.Y.) 1998;282(5393):1490-4.
1998: Terrence M Tumpey; H Cheng; Donald N Cook; Oliver Smithies; John E Oakes; Robert N Lausch
Absence of macrophage inflammatory protein-1alpha prevents the development of blinding herpes stromal keratitis.
Journal of virology 1998;72(5):3705-10.
1998: Jada Lewis; B Yang; R Kim; Halina Sierakowska; Ryszard Kole; Oliver Smithies; Nobuyo Maeda
A common human beta globin splicing mutation modeled in mice.
Blood 1998;91(6):2152-6.
1998: John R Hagaman; Jeffrey S Moyer; E S Bachman; M Sibony; Patricia L Magyar; Jeffrey E Welch; Oliver Smithies; John Krege; Deborah A O'Brien
Angiotensin-converting enzyme and male fertility.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2552-7.
1998: Paula M Oliver; S W John; K E Purdy; R Kim; Nobuyo Maeda; Michael F Goy; Oliver Smithies
Natriuretic peptide receptor 1 expression influences blood pressures of mice in a dose-dependent manner.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2547-51.
1998: Radu Daniel Rudic; Edward Shesely; Nobuyo Maeda; Oliver Smithies; Steven S Segal; William C Sessa
Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling.
The Journal of clinical investigation 1998;101(4):731-6.
1998: J B Whitney; A Leder; Jada Lewis; R A Popp; C Paszty; E M Rubin; W R Shehee; T M Townes; Oliver Smithies
Rapid genotyping of mice with hemoglobinopathies and globin transgenes.
Biochemical genetics 1998;36(1-2):65-77.
1998: Michael I Oliverio; K Madsen; CF Best; M Ito; Nobuyo Maeda; Oliver Smithies; Thomas M Coffman
Renal growth and development in mice lacking AT1A receptors for angiotensin II.
The American journal of physiology 1998;274(1 Pt 2):F43-50.
1997: Paula M Oliver; JE Fox; R Kim; Howard A Rockman; Hyung-Suk Kim; Robert L Reddick; Kailash N Pandey; Sharon L Milgram; Oliver Smithies; Nobuyo Maeda
Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14730-5.
1997: Oliver Smithies
Theodore Cooper Memorial Lecture. A mouse view of hypertension.
Hypertension 1997;30(6):1318-24.
1997: Hui-Feng Lin; Nobuyo Maeda; Oliver Smithies; David L Straight; Darrel W Stafford
A coagulation factor IX-deficient mouse model for human hemophilia B.
Blood 1997;90(10):3962-6.
1997: William Kuziel; S J Morgan; Tracey C Dawson; S Griffin; Oliver Smithies; K Ley; Nobuyo Maeda
Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(22):12053-8.
1997: Olga V Savinova; N Matsukawa; Oliver Smithies; Simon W M John
Mouse natriuretic peptide receptor 3 gene maps to proximal chromosome 15.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(10):788.
1997: John Krege; Jeffrey S Moyer; L L Langenbach; Lin Peng; S H Zhang; Nobuyo Maeda; Robert L Reddick; Oliver Smithies
Angiotensin-converting enzyme gene and atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(7):1245-50.
1997: B Tian; Qing C Meng; Yiu-Fai Chen; John Krege; Oliver Smithies; Suzanne Oparil
Blood pressures and cardiovascular homeostasis in mice having reduced or absent angiotensin-converting enzyme gene function.
Hypertension 1997;30(1 Pt 1):128-33.
1997: H Tsuda; C E Maynard-Currie; L H Reid; T Yoshida; K Edamura; Nobuyo Maeda; Oliver Smithies; Aya Jakobovits
Inactivation of the mouse HPRT locus by a 203-bp retroposon insertion and a 55-kb gene-targeted deletion: establishment of new HPRT-deficient mouse embryonic stem cell lines.
Genomics 1997;42(3):413-21.
1997: Michael I Oliverio; CF Best; Hyung-Suk Kim; William J Arendshorst; Oliver Smithies; Thomas M Coffman
Angiotensin II responses in AT1A receptor-deficient mice: a role for AT1B receptors in blood pressure regulation.
The American journal of physiology 1997;272(4 Pt 2):F515-20.
1997: TE MacTaggart; M Ito; Oliver Smithies; Simon W M John
Mouse angiotensin receptor genes Agtr1a and Agtr1b map to chromosomes 13 and 3.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(4):294-5.
1997: Robin L Davisson; Hyo-Soo Kim; John Krege; Donna J Lager; Oliver Smithies; Curt D Sigmund
Complementation of reduced survival, hypotension, and renal abnormalities in angiotensinogen-deficient mice by the human renin and human angiotensinogen genes.
The Journal of clinical investigation 1997;99(6):1258-64.
1997: Scott G Morham; Robert Langenbach; JF Mahler; Oliver Smithies
Characterization of prostaglandin H synthase 2 deficient mice and implications for mechanisms of NSAID action.
Advances in experimental medicine and biology 1997;407():131-8.
1997: Karl F Hilgers; Vasantha Reddi; John Krege; Oliver Smithies; R Ariel Gomez
Aberrant renal vascular morphology and renin expression in mutant mice lacking angiotensin-converting enzyme.
Hypertension 1997;29(1 Pt 2):216-21.
1997: John Krege; Hyung-Suk Kim; Jeffrey S Moyer; John Jennette; Lin Peng; S K Hiller; Oliver Smithies
Angiotensin-converting enzyme gene mutations, blood pressures, and cardiovascular homeostasis.
Hypertension 1997;29(1 Pt 2):150-7.
1996: Scott G Morham; K D Kluckman; N Voulomanos; Oliver Smithies
Targeted disruption of the mouse topoisomerase I gene by camptothecin selection.
Molecular and cellular biology 1996;16(12):6804-9.
1996: Edward Shesely; Nobuyo Maeda; Hyung-Suk Kim; K M Desai; John Krege; Victor E Laubach; P A Sherman; William C Sessa; Oliver Smithies
Elevated blood pressures in mice lacking endothelial nitric oxide synthase.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(23):13176-81.
1996: L R Toth; T J Smith; C Jones; H V de Silva; Oliver Smithies; Nobuyo Maeda
Two distinct apolipoprotein B alleles in mice generated by a single 'in-out' targeting.
Gene 1996;178(1-2):161-8.
1996: P T Bozza; J L Payne; Scott G Morham; R Langenbach; Oliver Smithies; Peter Weller
Leukocyte lipid body formation and eicosanoid generation: cyclooxygenase-independent inhibition by aspirin.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(20):11091-6.
1996: Suzanne L Kirby; Donald N Cook; W Walton; Oliver Smithies
Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(18):9402-7.
1996: S K Bronson; E G Plaehn; K D Kluckman; J R Hagaman; Nobuyo Maeda; Oliver Smithies
Single-copy transgenic mice with chosen-site integration.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):9067-72.
1996: Simon W M John; AT Veress; U Honrath; C K Chong; L Peng; Oliver Smithies; H Sonnenberg
Blood pressure and fluid-electrolyte balance in mice with reduced or absent ANP.
The American journal of physiology 1996;271(1 Pt 2):R109-14.
1996: Jada Lewis; B Yang; P Detloff; Oliver Smithies
Gene modification via "plug and socket" gene targeting.
The Journal of clinical investigation 1996;97(1):3-5.
1995: B Yang; Suzanne L Kirby; Jada Lewis; P J Detloff; Nobuyo Maeda; Oliver Smithies
A mouse model for beta 0-thalassemia.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(25):11608-12.
1995: Victor E Laubach; Edward Shesely; Oliver Smithies; P A Sherman
Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(23):10688-92.
1995: Robert Langenbach; Scott G Morham; Howard F Tiano; Charles D Loftin; B I Ghanayem; Patricia C Chulada; Joel Mahler; Christopher A Lee; Eugenia H Goulding; K D Kluckman; Hyung-Suk Kim; Oliver Smithies
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.
Cell 1995;83(3):483-92.
1995: Scott G Morham; Robert Langenbach; Charles D Loftin; Howard F Tiano; N Vouloumanos; John Jennette; Joel Mahler; K D Kluckman; A Ledford; Christopher A Lee; Oliver Smithies
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse.
Cell 1995;83(3):473-82.
1995: John F Couse; S W Curtis; T F Washburn; Jonathan Lindzey; T S Golding; D B Lubahn; Oliver Smithies; Kenneth S Korach
Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene.
Molecular endocrinology (Baltimore, Md.) 1995;9(11):1441-54.
1995: Donald N Cook; Melinda A Beck; T M Coffman; Suzanne L Kirby; john sheridan; I B Pragnell; Oliver Smithies
Requirement of MIP-1 alpha for an inflammatory response to viral infection.
Science (New York, N.Y.) 1995;269(5230):1583-5.
1995: Oliver Smithies; Nobuyo Maeda
Gene targeting approaches to complex genetic diseases: atherosclerosis and essential hypertension.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5266-72.
1995: John Krege; Simon W M John; L L Langenbach; Jeffrey B Hodgin; J R Hagaman; E S Bachman; John Jennette; Deborah A O'Brien; Oliver Smithies
Male-female differences in fertility and blood pressure in ACE-deficient mice.
Nature 1995;375(6527):146-8.
1995: John Krege; Jeffrey B Hodgin; J R Hagaman; Oliver Smithies
A noninvasive computerized tail-cuff system for measuring blood pressure in mice.
Hypertension 1995;25(5):1111-5.
1995: M Ito; Michael I Oliverio; PJ Mannon; CF Best; Nobuyo Maeda; Oliver Smithies; Thomas M Coffman
Regulation of blood pressure by the type 1A angiotensin II receptor gene.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3521-5.
1995: S K Bronson; Oliver Smithies; J T Mascarello
High incidence of XXY and XYY males among the offspring of female chimeras from embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3120-3.
1995: Hyung-Suk Kim; John Krege; K D Kluckman; J R Hagaman; Jeffrey B Hodgin; CF Best; John Jennette; Thomas M Coffman; Nobuyo Maeda; Oliver Smithies
Genetic control of blood pressure and the angiotensinogen locus.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2735-9.
1995: Simon W M John; John Krege; Paula M Oliver; J R Hagaman; Jeffrey B Hodgin; S C Pang; T G Flynn; Oliver Smithies
Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension.
Science (New York, N.Y.) 1995;267(5198):679-81.
1995: Oliver Smithies
Early days of gel electrophoresis.
Genetics 1995;139(1):1-4.
1994: S K Bronson; Oliver Smithies
Altering mice by homologous recombination using embryonic stem cells.
The Journal of biological chemistry 1994;269(44):27155-8.
1994: P J Detloff; Jada Lewis; Simon W M John; W R Shehee; Robert Langenbach; Nobuyo Maeda; Oliver Smithies
Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy.
Molecular and cellular biology 1994;14(10):6936-43.
1994: Oliver Smithies; Hyung-Suk Kim
Targeted gene duplication and disruption for analyzing quantitative genetic traits in mice.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(9):3612-5.
1993: D B Lubahn; Jeffrey S Moyer; T S Golding; John F Couse; Kenneth S Korach; Oliver Smithies
Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11162-6.
1993: T Coffman; S Geier; S Ibrahim; R Griffiths; Robert F Spurney; Oliver Smithies; Beverly H Koller; Alfred P. Sanfilippo
Improved renal function in mouse kidney allografts lacking MHC class I antigens.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(1):425-35.
1993: N C Luetteke; T H Qiu; Robert Peiffer Jr; P Oliver; Oliver Smithies; David C Lee
TGF alpha deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice.
Cell 1993;73(2):263-78.
1993: W R Shehee; Paula M Oliver; Oliver Smithies
Lethal thalassemia after insertional disruption of the mouse major adult beta-globin gene.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3177-81.
1993: Oliver Smithies
Animal models of human genetic diseases.
Trends in genetics : TIG 1993;9(4):112-6.
1993: Niraj Desai; H Bassiri; J Kim; Beverly H Koller; Oliver Smithies; Clyde F Barker; Ali Naji; James F Markmann
Islet allograft, islet xenograft, and skin allograft survival in CD8+ T lymphocyte-deficient mice.
Transplantation 1993;55(4):718-22.
1993: Niraj Desai; H Bassiri; J S Odorico; Beverly H Koller; Oliver Smithies; Ali Naji; Clyde F Barker; James F Markmann
Pancreatic islet allograft and xenograft survival in CD8+ T-lymphocyte-deficient recipients.
Transplantation proceedings 1993;25(1 Pt 2):961-2.
1993: Hyung-Suk Kim; K M Lyons; Eiichi Saitoh; Edwin Azen; Oliver Smithies; Nobuyo Maeda
The structure and evolution of the human salivary proline-rich protein gene family.
Mammalian genome : official journal of the International Mammalian Genome Society 1993;4(1):3-14.
1992: James F Markmann; H Bassiri; Niraj Desai; J S Odorico; J I Kim; Beverly H Koller; Oliver Smithies; Clyde F Barker
Indefinite survival of MHC class I-deficient murine pancreatic islet allografts.
Transplantation 1992;54(6):1085-9.
1992: L L Clarke; Barbara R Grubb; Sherif E Gabriel; Oliver Smithies; Beverly H Koller; Richard C Boucher
Defective epithelial chloride transport in a gene-targeted mouse model of cystic fibrosis.
Science (New York, N.Y.) 1992;257(5073):1125-8.
1992: John N Snouwaert; K K Brigman; Anne M Latour; Nadia Anderson; Richard C Boucher; Oliver Smithies; Beverly H Koller
An animal model for cystic fibrosis made by gene targeting.
Science (New York, N.Y.) 1992;257(5073):1083-8.
1992: Melanie Spriggs; Beverly H Koller; T Sato; PJ Morrissey; W C Fanslow; Oliver Smithies; R F Voice; M B Widmer; Charles R Maliszewski
Beta 2-microglobulin-, CD8+ T-cell-deficient mice survive inoculation with high doses of vaccinia virus and exhibit altered IgG responses.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(13):6070-4.
1992: Beverly H Koller; Oliver Smithies
Altering genes in animals by gene targeting.
Annual review of immunology 1992;10():705-30.
1991: Beverly H Koller; Hyung-Suk Kim; Anne M Latour; K Brigman; Richard C Boucher; P Scambler; B Wainwright; Oliver Smithies
Toward an animal model of cystic fibrosis: targeted interruption of exon 10 of the cystic fibrosis transmembrane regulator gene in embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(23):10730-4.
1991: F Schwartz; Nobuyo Maeda; Oliver Smithies; Robert Hickey; Winfried Edelmann; Arthur I Skoultchi; R Kucherlapati
A dominant positive and negative selectable gene for use in mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(23):10416-20.
1991: V Valancius; Oliver Smithies
Double-strand gap repair in a mammalian gene targeting reaction.
Molecular and cellular biology 1991;11(9):4389-97.
1991: Hyung-Suk Kim; B W Popovich; W R Shehee; Edward Shesely; Oliver Smithies
Problems encountered in detecting a targeted gene by the polymerase chain reaction.
Gene 1991;103(2):227-33.
1991: Edward Shesely; Hyung-Suk Kim; W R Shehee; T Papayannopoulou; Oliver Smithies; B W Popovich
Correction of a human beta S-globin gene by gene targeting.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(10):4294-8.
1991: A B Metzenberg; G Wurzer; T H Huisman; Oliver Smithies
Homology requirements for unequal crossing over in humans.
Genetics 1991;128(1):143-61.
1991: LH Reid; Edward Shesely; Hyung-Suk Kim; Oliver Smithies
Cotransformation and gene targeting in mouse embryonic stem cells.
Molecular and cellular biology 1991;11(5):2769-77.
1991: V Valancius; Oliver Smithies
Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells.
Molecular and cellular biology 1991;11(3):1402-8.
1990: Beverly H Koller; P Marrack; J W Kappler; Oliver Smithies
Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.
Science (New York, N.Y.) 1990;248(4960):1227-30.
1990: LH Reid; R G Gregg; Oliver Smithies; Beverly H Koller
Regulatory elements in the introns of the human HPRT gene are necessary for its expression in embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(11):4299-303.
1990: Hyung-Suk Kim; Oliver Smithies; Nobuyo Maeda
A physical map of the human salivary proline-rich protein gene cluster covers over 700 kbp of DNA.
Genomics 1990;6(2):260-7.
1990: Paula S Henthorn; Oliver Smithies; D L Mager
Molecular analysis of deletions in the human beta-globin gene cluster: deletion junctions and locations of breakpoints.
Genomics 1990;6(2):226-37.
1989: Beverly H Koller; Oliver Smithies
Inactivating the beta 2-microglobulin locus in mouse embryonic stem cells by homologous recombination.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(22):8932-5.
1989: Beverly H Koller; L J Hagemann; T Doetschman; J R Hagaman; S Huang; P J Williams; N L First; Nobuyo Maeda; Oliver Smithies
Germ-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(22):8927-31.
1989: D J Endean; Oliver Smithies
Replication of plasmid DNA in fertilized Xenopus eggs is sensitive to both the topology and size of the injected template.
Chromosoma 1989;97(4):307-14.
1988: T Doetschman; Nobuyo Maeda; Oliver Smithies
Targeted mutation of the Hprt gene in mouse embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(22):8583-7.
1988: Nobuyo Maeda; D L Ebert; T M Doers; M Newman; J Hasler-Rapacz; Alan D Attie; J Rapacz; Oliver Smithies
Molecular genetics of the apolipoprotein B gene in pigs in relation to atherosclerosis.
Gene 1988;70(2):213-29.
1988: Hyung-Suk Kim; Oliver Smithies
Recombinant fragment assay for gene targetting based on the polymerase chain reaction.
Nucleic acids research 1988;16(18):8887-903.
1988: K M Lyons; Edwin Azen; P A Goodman; Oliver Smithies
Many protein products from a few loci: assignment of human salivary proline-rich proteins to specific loci.
Genetics 1988;120(1):255-65.
1988: K M Lyons; J H Stein; Oliver Smithies
Length polymorphisms in human proline-rich protein genes generated by intragenic unequal crossing over.
Genetics 1988;120(1):267-78.
1988: A K Nandi; R S Roginski; R G Gregg; Oliver Smithies; Arthur I Skoultchi
Regulated expression of genes inserted at the human chromosomal beta-globin locus by homologous recombination.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(11):3845-9.
1988: Eiichi Saitoh; S Isemura; K Sanada; Hyung-Suk Kim; Oliver Smithies; Nobuyo Maeda
Cystatin superfamily. Evidence that family II cystatin genes are evolutionarily related to family III cystatin genes.
Biological chemistry Hoppe-Seyler 1988;369 Suppl():191-7.
1987: T Doetschman; R G Gregg; Nobuyo Maeda; M L Hooper; David W Melton; S Thompson; Oliver Smithies
Targetted correction of a mutant HPRT gene in mouse embryonic stem cells.
Nature 1987;330(6148):576-8.
1987: K Y Song; F Schwartz; Nobuyo Maeda; Oliver Smithies; R Kucherlapati
Accurate modification of a chromosomal plasmid by homologous recombination in human cells.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(19):6820-4.
1987: E Saitoh; Hyung-Suk Kim; Oliver Smithies; Nobuyo Maeda
Human cysteine-proteinase inhibitors: nucleotide sequence analysis of three members of the cystatin gene family.
Gene 1987;61(3):329-38.
1987: Arthur I Skoultchi; A Nandi; R S Roginski; R G Gregg; Oliver Smithies
Expression of genes inserted at the human beta-globin locus by homologous recombination.
Progress in clinical and biological research 1987;251():581-94.
1986: S S Boggs; R G Gregg; N Borenstein; Oliver Smithies
Efficient transformation and frequent single-site, single-copy insertion of DNA can be obtained in mouse erythroleukemia cells transformed by electroporation.
Experimental hematology 1986;14(10):988-94.
1986: Nobuyo Maeda; S M McEvoy; H F Harris; T H Huisman; Oliver Smithies
Polymorphisms in the human haptoglobin gene cluster: chromosomes with multiple haptoglobin-related (Hpr) genes.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(19):7395-9.
1986: Paula S Henthorn; D L Mager; T H Huisman; Oliver Smithies
A gene deletion ending within a complex array of repeated sequences 3' to the human beta-globin gene cluster.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(14):5194-8.
1986: P A Powers; Oliver Smithies
Short gene conversions in the human fetal globin gene region: a by-product of chromosome pairing during meiosis?
Genetics 1986;112(2):343-58.
1986: Oliver Smithies; P A Powers
Gene conversions and their relation to homologous chromosome pairing.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1986;312(1154):291-302.
1986: R G Gregg; Oliver Smithies
Targeted modification of human chromosomal genes.
Cold Spring Harbor symposia on quantitative biology 1986;51 Pt 2():1093-9.
1986: Oliver Smithies
Direct alteration of a gene in the human genome.
Journal of inherited metabolic disease 1986;9 Suppl 1():92-7.
1986: Nobuyo Maeda; Oliver Smithies
The evolution of multigene families: human haptoglobin genes.
Annual review of genetics 1986;20():81-108.
1985: Q Li; P A Powers; Oliver Smithies
Nucleotide sequence of 16-kilobase pairs of DNA 5' to the human epsilon-globin gene.
The Journal of biological chemistry 1985;260(28):14901-10.
1985: D L Mager; Paula S Henthorn; Oliver Smithies
A Chinese G gamma + (A gamma delta beta)zero thalassemia deletion: comparison to other deletions in the human beta-globin gene cluster and sequence analysis of the breakpoints.
Nucleic acids research 1985;13(18):6559-75.
1985: Oliver Smithies; R G Gregg; S S Boggs; M A Koralewski; R S Kucherlapati
Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination.
Nature 1985;317(6034):230-4.
1985: Nobuyo Maeda; Hyung-Suk Kim; E A Azen; Oliver Smithies
Differential RNA splicing and post-translational cleavages in the human salivary proline-rich protein gene system.
The Journal of biological chemistry 1985;260(20):11123-30.
1985: P S Henthorn; Oliver Smithies; T Nakatsuji; Alex E Felice; M B Gardiner; A L Reese; TH Huisman
(A gamma delta beta)0-Thalassaemia in Blacks is due to a deletion of 34 kbp of DNA.
British journal of haematology 1985;59(2):343-56.
1984: P A Powers; C Altay; T H Huisman; Oliver Smithies
Two novel arrangements of the human fetal globin genes: G gamma-G gamma and A gamma-A gamma.
Nucleic acids research 1984;12(18):7023-34.
1984: Edwin Azen; K M Lyons; T McGonigal; N L Barrett; L S Clements; Nobuyo Maeda; E F Vanin; D M Carlson; Oliver Smithies
Clones from the human gene complex coding for salivary proline-rich proteins.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(17):5561-5.
1984: Nobuyo Maeda; Funmei Yang; D R Barnett; B H Bowman; Oliver Smithies
Duplication within the haptoglobin Hp2 gene.
Nature 1984;309(5964):131-5.
1984: R S Kucherlapati; E M Eves; K Y Song; B S Morse; Oliver Smithies
Homologous recombination between plasmids in mammalian cells can be enhanced by treatment of input DNA.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(10):3153-7.
1984: J Devereux; P Haeberli; Oliver Smithies
A comprehensive set of sequence analysis programs for the VAX.
Nucleic acids research 1984;12(1 Pt 1):387-95.
1984: Oliver Smithies; M A Koralewski; K Y Song; R S Kucherlapati
Homologous recombination with DNA introduced into mammalian cells.
Cold Spring Harbor symposia on quantitative biology 1984;49():161-70.
1983: E F Vanin; P S Henthorn; D Kioussis; Frank Grosveld; Oliver Smithies
Unexpected relationships between four large deletions in the human beta-globin gene cluster.
Cell 1983;35(3 Pt 2):701-9.
1983: R S Roginski; Arthur I Skoultchi; P Henthorn; Oliver Smithies; N Hsiung; R Kucherlapati
Coordinate modulation of transfected HSV thymidine kinase and human globin genes.
Cell 1983;35(1):149-55.
1983: Nobuyo Maeda; J B Bliska; Oliver Smithies
Recombination and balanced chromosome polymorphism suggested by DNA sequences 5' to the human delta-globin gene.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(16):5012-6.
1982: S H Shen; Oliver Smithies
Human globin psi B2 is not a globin-related sequence.
Nucleic acids research 1982;10(23):7809-18.
1982: N Hsiung; R S Roginski; P Henthorn; Oliver Smithies; R Kucherlapati; Arthur I Skoultchi
Introduction and expression of a fetal human globin gene in mouse fibroblasts.
Molecular and cellular biology 1982;2(4):401-11.
1982: Oliver Smithies
The control of globin and other eukaryotic genes.
Journal of cellular physiology. Supplement 1982;1():137-43.
1981: Oliver Smithies; W R Engels; J R Devereux; Jerry L Slightom; S Shen
Base substitutions, length differences and DNA strand asymmetries in the human G gamma and A gamma fetal globin gene region.
Cell 1981;26(3 Pt 1):345-53.
1981: S H Shen; Jerry L Slightom; Oliver Smithies
A history of the human fetal globin gene duplication.
Cell 1981;26(2 Pt 2):191-203.
1981: M D Poulik; C S Shinnick; Oliver Smithies
Partial amino acid sequences of human and dog post-gamma globulins.
Molecular immunology 1981;18(6):569-72.
1980: Jerry L Slightom; A E Blechl; Oliver Smithies
Human fetal G gamma- and A gamma-globin genes: complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genes.
Cell 1980;21(3):627-38.
1980: A Efstratiadis; J W Posakony; T Maniatis; R M Lawn; C O'Connell; R A Spritz; J K DeRiel; B G Forget; S M Weissman; Jerry L Slightom; A E Blechl; Oliver Smithies; F E Baralle; C C Shoulders; N J Proudfoot
The structure and evolution of the human beta-globin gene family.
Cell 1980;21(3):653-68.
1980: E F Vanin; G I Goldberg; P W Tucker; Oliver Smithies
A mouse alpha-globin-related pseudogene lacking intervening sequences.
Nature 1980;286(5770):222-6.
1979: M D Poulik; Oliver Smithies
Partial amino acid sequences of rabbit and rat beta 2-microglobulins.
Molecular immunology 1979;16(9):731-4.
1978: Oliver Smithies; A E Blechl; K Denniston-Thompson; N Newell; Julia E Richards; Jerry L Slightom; P W Tucker; F R Blattner
Cloning human fetal gamma globin and mouse alpha-type globin DNA: characterization and partial sequencing.
Science (New York, N.Y.) 1978;202(4374):1284-9.
1978: F R Blattner; A E Blechl; K Denniston-Thompson; H E Faber; Julia E Richards; Jerry L Slightom; P W Tucker; Oliver Smithies
Cloning human fetal gamma globin and mouse alpha-type globin DNA: preparation and screening of shotgun collections.
Science (New York, N.Y.) 1978;202(4374):1279-84.
1978: Blas Frangione; E C Franklin; Oliver Smithies
Unusual genes at the aminoterminus of human immunoglobulin variants.
Nature 1978;273(5661):400-1.
1978: E F Freedlender; L Taichman; Oliver Smithies
Segregation of some chromosomal proteins during cell replication.
Cold Spring Harbor symposia on quantitative biology 1978;42 Pt 1():417-20.
1977: B Ballou; Oliver Smithies
A simplified chloral hydrate electrophoresis system for analysis of biological membranes.
Analytical biochemistry 1977;80(2):616-23.
1977: E F Freedlender; L Taichman; Oliver Smithies
Nonrandom distribution of chromosomal proteins during cell replication.
Biochemistry 1977;16(9):1802-8.
1977: F R Blattner; B G Williams; A E Blechl; K Denniston-Thompson; H E Faber; L Furlong; D J Grunwald; D O Kiefer; D D Moore; J W Schumm; E L Sheldon; Oliver Smithies
Charon phages: safer derivatives of bacteriophage lambda for DNA cloning.
Science (New York, N.Y.) 1977;196(4286):161-9.
1976: B Ballou; D J McKean; E F Freedlender; Oliver Smithies
HLA membrane antigens: sequencing by intrinsic radioactivity.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(12):4487-91.
1976: H E Faber; R S Kucherlapati; M D Poulik; F H Ruddle; Oliver Smithies
beta2-microglobulin locus on human chromosome 15.
Somatic cell genetics 1976;2(2):141-53.
1976: R S Kucherlapati; H E Faber; M D Poulik; F H Ruddle; Oliver Smithies
Assignment of the gene for beta-2-microglobulin to human chromosome 15.
Cytogenetics and cell genetics 1976;16(1-5):178-80.
1975: M D Poulik; D Farrah; G H Malek; C J Shinnick; Oliver Smithies
Low molecular weight urinary proteins. I. Partial amino acid sequences of the retinol-binding proteins of man and dog.
Biochimica et biophysica acta 1975;412(2):326-34.
1975: T M Shinnick; E Lund; Oliver Smithies; F R Blattner
Hybridization of labeled RNA to DNA in agarose gels.
Nucleic acids research 1975;2(10):1911-29.
1974: Oliver Smithies
Letter: Recombinant DNA molecules.
Genetics 1974;77(4):819-20.
1974: D J McKean; E H Peters; J I Waldby; Oliver Smithies
Amino acid sequence determination with radioactive proteins.
Biochemistry 1974;13(15):3048-51.
1974: J S Finlayson; M Potter; C S Shinnick; Oliver Smithies
Components of the major urinary protein complex of inbred mice: determination of NH2-terminal sequences and comparison with homologous components from wild mice.
Biochemical genetics 1974;11(4):325-35.
1974: Oliver Smithies
Immunoglobulin genes: arranged in tandem or in parallel?
Cold Spring Harbor symposia on quantitative biology 1974;38():725-37.
1973: J W Fett; H F Deutsch; Oliver Smithies
Hinge-region deletion localized in the IgG-globulin Mcg.
Immunochemistry 1973;10(2):115-8.
1972: Oliver Smithies; M D Poulik
Dog homologue of human 2 -microglobulin.
Proceedings of the National Academy of Sciences of the United States of America 1972;69(10):2914-7.
1972: S E Kornguth; L R Kozel; Oliver Smithies
Probable identity of tissue specific histone with encephalitogenic protein.
Nature: New biology 1972;237(71):49-50.
1972: Oliver Smithies; M D Poulik
Initiation of protein synthesis at an unusual position in an immunoglobulin gene?
Science (New York, N.Y.) 1972;175(4018):187-9.
1971: Oliver Smithies; D Gibson; E M Fanning; R M Goodfliesh; J G Gilman; D L Ballantyne
Quantitative procedures for use with the Edman-Begg sequenator. Partial sequences of two unusual immunoglobulin light chains, Rzf and Sac.
Biochemistry 1971;10(26):4912-21.
1971: M D Poulik; D L Ballantyne; C J Shinnick; Oliver Smithies
Partial amino acid sequences of two urinary proteins characteristic of tubular proteinemia.
The Journal of laboratory and clinical medicine 1971;78(5):822.
1971: D Gibson; M Levanon; Oliver Smithies
Heterogeneity of normal human immunoglobulin light chains. Nonallelic variation in the constant region of lambda chains.
Biochemistry 1971;10(16):3114-22.
1971: Oliver Smithies; D M Gibson; E M Fanning; M E Percy; D M Parr; G E Connell
Deletions in immunoglobulin polypeptide chains as evidence for breakage and repair in DNA.
Science (New York, N.Y.) 1971;172(3983):574-7.
1971: M T Sung; G H Dixon; Oliver Smithies
Phosphorylation and synthesis of histones in regenerating rat liver.
The Journal of biological chemistry 1971;246(5):1358-64.
1970: Oliver Smithies
Pathways through networks of branched DNA.
Science (New York, N.Y.) 1970;169(3948):882-3.
1969: E A Azen; Oliver Smithies; O Hiller
High-voltage starch-gel electrophoresis in the study of post-albumin proteins and C'3(beta 1-c-globulin) polymorphism.
Biochemical genetics 1969;3(3):215-28.
1969: M Sung; Oliver Smithies
Differential elution of histones from gel-trapped nuclei.
Biopolymers 1969;7(1):39-58.
1968: E A Azen; Oliver Smithies
Genetic polymorphism of C'3(beta1C-globulin) in human serum.
Science (New York, N.Y.) 1968;162(3856):905-7.
1968: Oliver Smithies
Genetics of variability.
Brookhaven symposia in biology 1968;21(1):243-58.
1968: J G Gilman; Oliver Smithies
Fetal hemoglobin variants in mice.
Science (New York, N.Y.) 1968;160(3830):885-6.
1968: T G Wegmann; Oliver Smithies
Improvement of the microtiter hemagglutination method.
Transfusion 1968;8(1):47.
1967: A J Claflin; Oliver Smithies
Antibody-producing cells in division.
Science (New York, N.Y.) 1967;157(3796):1561-2.
1967: Oliver Smithies
Antibody variability. Somatic recombination between the elements of "antibody gene pairs" may explain antibody variability.
Science (New York, N.Y.) 1967;157(3786):267-73.
1966: G E Connell; Oliver Smithies; G H Dixon
Gene action in the human haptoglobins. II. Isolation and physical characterization of alpha polypeptide chains.
Journal of molecular biology 1966;21(2):225-9.
1966: Oliver Smithies; G E Connell; G H Dixon
Gene action in the human haptoglobins. I. Dissociation into constituent polypeptide chains.
Journal of molecular biology 1966;21(2):213-24.
1966: A J Claflin; Oliver Smithies; R K Meyer
Antibody responses in bursa-deficient chickens.
Journal of immunology (Baltimore, Md. : 1950) 1966;97(5):693-9.
1966: Oliver Smithies
Somatic mutations and proteins.
Proceedings of the Royal Society of London. Series B, Containing papers of a Biological character. Royal Society (Great Britain) 1966;164(995):320-7.
1966: R Ceppellini; S Dray; J L Fahey; E C Franklin; H Fudenberg; P G Gell; H C Goodman; R Grubb; M Harboe; R L Kirk; J Oudin; C Ropartz; Oliver Smithies; A G Steinberg; Z Trnka
[Nomenclature of genetically determined characteristics of human immunoglobulins].
Humangenetik 1966;2(3):317-22.
1965: Oliver Smithies
Disulfide-bond cleavage and formation in proteins.
Science (New York, N.Y.) 1965;150(3703):1595-8.
1965: Oliver Smithies
CHARACTERIZATION OF GENETIC VARIANTS OF BLOOD PROTEINS.
Vox sanguinis 1965;10():359-62.
1965: E A AZEN; S ORR; Oliver Smithies
STARCH-GEL ELECTROPHORESIS OF ERYTHROCYTE STROMA.
The Journal of laboratory and clinical medicine 1965;65():440-9.
1965: Oliver Smithies
Chromosomal rearrangements and protein structure.
Bibliotheca haematologica 1965;23():373-4.
1965: Oliver Smithies
Characterization of genetic variants of blood proteins.
Bibliotheca haematologica 1965;23():1175-7.
1964: Oliver Smithies
GEL ELECTROPHORESIS: INTRODUCTORY REMARKS.
Annals of the New York Academy of Sciences 1964;121():309.
1964: Oliver Smithies
STARCH-GEL ELECTROPHORESIS.
Metabolism: clinical and experimental 1964;13():SUPPL:974-84.
1964: Oliver Smithies
CHROMOSOMAL REARRANGEMENTS AND PROTEIN STRUCTURE.
Cold Spring Harbor symposia on quantitative biology 1964;29():309-19.
1963: W E NANCE; A CLAFLIN; Oliver Smithies
LACTIC DEHYDROGENASE: GENETIC CONTROL IN MAN.
Science (New York, N.Y.) 1963;142(3595):1075-7.
1963: Oliver Smithies
GAMMA-GLOBULIN VARIABILITY: A GENETIC HYPOTHESIS.
Nature 1963;199():1231-6.
1963: W E NANCE; Oliver Smithies
New haptoglobin alleles: a prediction confirmed.
Nature 1963;198():869-70.
1962: Oliver Smithies; G E CONNELL; G H DIXON
Chromosomal rearrangements and the evolution of haptoglobin genes.
Nature 1962;196():232-6.
1962: J O Mueller; Oliver Smithies; M R Irwin
Transferrin Variation in Columbidae.
Genetics 1962;47(10):1385-92.
1962: Oliver Smithies
Molecular size and starch-gel electrophoresis.
Archives of biochemistry and biophysics 1962;Suppl 1():125-31.
1962: N E SIMPSON; H H GUNSON; Oliver Smithies
Frequencies of blood groups, serum haptoglobins and levels of slow alpha2-globulin in diabetics and their relatives.
Diabetes 1962;11():329-33.
1962: Oliver Smithies; G E CONNELL; G H DIXON
Inheritance of haptoglobin subtypes.
American journal of human genetics 1962;14():14-21.
1962: G E CONNELL; G H DIXON; Oliver Smithies
Subdivision of the three common haptoglobin types based on 'hidden' diffrences.
Nature 1962;193():505-6.
1960: H HARRIS; S D LAWLER; E B ROBSON; Oliver Smithies
The occurrence of two unusual serum protein phenotypes in a single pedigree.
Annals of human genetics 1960;24():63-9.
1959: E R GIBLETT; C G HICKMAN; Oliver Smithies
Serum transferrins.
Nature 1959;183(4675):1589-90.
1959: Oliver Smithies; O HILLER
The genetic control of transferrins in humans.
The Biochemical journal 1959;72(1):121-6.
1959: G E CONNELL; Oliver Smithies
Human haptoglobins: estimation and purification.
The Biochemical journal 1959;72(1):115-21.
1959: Oliver Smithies
An improved procedure for starch-gel electrophoresis: further variations in the serum proteins of normal individuals.
The Biochemical journal 1959;71(3):585-7.
1959: Oliver Smithies
Zone electrophoresis in starch gels and its application to studies of serum proteins.
Advances in protein chemistry 1959;14():65-113.
1958: W R HORSFALL; Oliver Smithies
Genetic control of some human serum beta-globulins.
Science (New York, N.Y.) 1958;128(3314):35.
1958: Oliver Smithies; C G Hickman
Inherited Variations in the Serum Proteins of Cattle.
Genetics 1958;43(3):374-85.
1958: Oliver Smithies
Third allele at the serum beta-globulin locus in humans.
Nature 1958;181(4617):1203-4.
1958: M D POULIK; Oliver Smithies
Comparison and combination of the starch-gel and filter-paper electrophoretic methods applied to human sera: two-dimensional electrophoresis.
The Biochemical journal 1958;68(4):636-43.
1957: Oliver Smithies
Variations in human serum beta-globulins.
Nature 1957;180(4600):1482-3.
1957: G H DIXON; Oliver Smithies
Zone electrophoresis of cabbage enzymes in starch gels.
Biochimica et biophysica acta 1957;23(1):198-9.
1956: Oliver Smithies; N F WALKER
Notation for serum-protein groups and the genes controlling their inheritance.
Nature 1956;178(4535):694-5.
1956: Oliver Smithies; M D POULIK
Two-dimensional electrophoresis of serum proteins.
Nature 1956;177(4518):1033.
1955: Oliver Smithies; N F WALKER
Genetic control of some serum proteins in normal humans.
Nature 1955;176(4496):1265-6.
1955: Oliver Smithies
Zone electrophoresis in starch gels: group variations in the serum proteins of normal human adults.
The Biochemical journal 1955;61(4):629-41.
1955: Oliver Smithies
Grouped variations in the occurrence of new protein components in normal human serum.
Nature 1955;175(4450):307-8.
1954: Oliver Smithies
The application of four methods for assessing protein homogeneity to crystalline beta-lactoglobulin: an anomaly in phase rule solubility tests.
The Biochemical journal 1954;58(1):31-8.
1953: Oliver Smithies
A dynamic osmometer for accurate measurements on small quantities of material: osmotic pressures of isoelectric beta-lactoglobulin solutions.
The Biochemical journal 1953;55(1):57-67.
1948: A G OGSTON; Oliver Smithies
Some thermodynamic and kinetic aspects of metabolic phosphorylation.
Physiological reviews 1948;28(3):283-303.