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Paul Smits

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Anna M J Thijs; Winette T A van der Graaf; C M L van Herpen; Anneke Geurts-Moespot; Paul Smits; Fred C G J Sweep; Gerard A Rongen
Role of endogenous vascular endothelial growth factor in endothelium-dependent vasodilation in humans.
Joris van Drongelen; Carlijn R Hooijmans; Fred K Lotgering; Paul Smits; Marc E A Spaanderman
Adaptive changes of mesenteric arteries in pregnancy: a meta-analysis.
Bart P Ramakers; Niels P Riksen; Gerard A Rongen; Paul Smits; Petra H H van den Broek; Johannes G van der Hoeven; Kimberley E Wever; Matthijs Kox; Rosalinde Masereeuw; Faustin Mbuyi; Peter Pickkers
How systemic inflammation modulates adenosine metabolism and adenosine receptor expression in humans in vivo.

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2013: Anna M J Thijs; Winette T A van der Graaf; C M L van Herpen; Anneke Geurts-Moespot; Paul Smits; Fred C G J Sweep; Gerard A Rongen
Role of endogenous vascular endothelial growth factor in endothelium-dependent vasodilation in humans.
Hypertension 2013;61(5):1060-5.
2012: Joris van Drongelen; Carlijn R Hooijmans; Fred K Lotgering; Paul Smits; Marc E A Spaanderman
Adaptive changes of mesenteric arteries in pregnancy: a meta-analysis.
American journal of physiology. Heart and circulatory physiology 2012;303(6):H639-57.
2012: Bart P Ramakers; Niels P Riksen; Gerard A Rongen; Paul Smits; Petra H H van den Broek; Johannes G van der Hoeven; Kimberley E Wever; Matthijs Kox; Rosalinde Masereeuw; Faustin Mbuyi; Peter Pickkers
How systemic inflammation modulates adenosine metabolism and adenosine receptor expression in humans in vivo.
Critical care medicine 2012;40(9):2609-16.
2012: Richard Engbersen; Rosalinde Masereeuw; MM Moons; Helene L M Siero; Paul Smits; Miriam A van Gestel; Frans G M Russel
Differential effects of sulfonylurea derivatives on vascular ATP-sensitive potassium channels.
European journal of pharmacology 2012;681(1-3):75-9.
2012: Richard Engbersen; Patrick Meijer; Marc J Mol; Wim J G Oyen; Niels P Riksen; Gerard A Rongen; Otto C Boerman; Bert Bravenboer; Cees Tack; Paul Smits
Improved resistance to ischemia and reperfusion, but impaired protection by ischemic preconditioning in patients with type 1 diabetes mellitus: a pilot study.
Cardiovascular diabetology 2012;11():124.
2012: Constantijn W Wouters; Paul Smits; Otto C Boerman; Geert W J Frederix; Carola I F Janssen; Patrick Meijer; Wim J Oyen; Gerard A Rongen
Atorvastatin does not affect ischaemia-induced phosphatidylserine exposition in humans in-vivo.
Journal of atherosclerosis and thrombosis 2012;19(3):285-91.
2011: Marlies Bosselaar; Paul Smits; Luc J C van Loon; Cees J Tack
Intravenous AICAR during hyperinsulinemia induces systemic hemodynamic changes but has no local metabolic effect.
Journal of clinical pharmacology 2011;51(10):1449-58.
2011: Bart P Ramakers; Niels P Riksen; Paul Smits; Johannes G van der Hoeven; Peter Pickkers
Modulation of innate immunity by adenosine receptor stimulation.
Shock (Augusta, Ga.) 2011;36(3):208-15.
2011: Joris van Drongelen; Alfons Wouterse; Fred C G J Sweep; Rob Hermsen; Fred K Lotgering; Jeanne Pertijs; Paul Smits; Marc E A Spaanderman
Contribution of different local vascular responses to mid-gestational vasodilation.
American journal of obstetrics and gynecology 2011;205(2):155.e12-7.
2011: Patrick Meijer; Constantijn W Wouters; Wim J Oyen; Otto C Boerman; Gert Jan Scheffer; Paul Smits; Gerard A Rongen
Angiotensin II type 1 receptor blockade does not enhance apoptotic cell death during ischemia and reperfusion in humans in vivo.
Journal of cardiovascular pharmacology 2011;57(6):702-6.
2011: Joris van Drongelen; Ivo H J Ploemen; Jeanne Pertijs; Jonathan H Gooi; Fred C G J Sweep; Fred K Lotgering; Marc E A Spaanderman; Paul Smits
Aging attenuates the vasodilator response to relaxin.
American journal of physiology. Heart and circulatory physiology 2011;300(5):H1609-15.
2011: B J J W Schouwenberg; Paul Smits; Cees J Tack; Bastiaan E De Galan
The effect of antecedent hypoglycaemia on β₂-adrenergic sensitivity in healthy participants with the Arg16Gly polymorphism of the β₂-adrenergic receptor.
Diabetologia 2011;54(5):1212-8.
2011: A J Rennings; Frans G M Russel; Y Li; P M Deen; R Masereeuw; Cees J Tack; Paul Smits
Preserved response to diuretics in rosiglitazone-treated subjects with insulin resistance: a randomized double-blind placebo-controlled crossover study.
Clinical pharmacology and therapeutics 2011;89(4):587-94.
2011: Douwe Dekker; Mirrin J Dorresteijn; Margot Pijnenburg; Suzanne Heemskerk; Anja Rasing-Hoogveld; David M Burger; Frank A D T G Wagener; Paul Smits
The bilirubin-increasing drug atazanavir improves endothelial function in patients with type 2 diabetes mellitus.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(2):458-63.
2011: Marinette van der Graaf; Jacco H de Haan; Paul Smits; Alexandra H Mulder; Arend Heerschap; Cees J Tack
The effect of acute exercise on glycogen synthesis rate in obese subjects studied by 13C MRS.
European journal of applied physiology 2011;111(2):275-83.
2011: Bart P Ramakers; Niels P Riksen; Paul Smits; Thijmen H Stal; Petra van den Broek; Johannes G van der Hoeven; Suzanne Heemskerk; Wilbert H M Peters; Peter Pickkers
Dipyridamole augments the antiinflammatory response during human endotoxemia.
Critical care (London, England) 2011;15(6):R289.
2011: Bart P Ramakers; Niels P Riksen; Paul Smits; Petra van den Broek; Johannes G van der Hoeven; Barbara Franke; Wilbert H M Peters; Peter Pickkers
Circulating adenosine increases during human experimental endotoxemia but blockade of its receptor does not influence the immune response and subsequent organ injury.
Critical care (London, England) 2011;15(1):R3.
2011: Niels P Riksen; Paul Smits; Gerard A Rongen
The cardiovascular effects of methylxanthines.
Handbook of experimental pharmacology 2011;(200):413-37.
2010: Jan T Groothuis; Gerard A Rongen; Alexander C H Geurts; Paul Smits; Maria T E Hopman
Effect of different sympathetic stimuli-autonomic dysreflexia and head-up tilt-on leg vascular resistance in spinal cord injury.
Archives of physical medicine and rehabilitation 2010;91(12):1930-5.
2010: Marc E Gomes; Cees J Tack; Freek W Verheugt; Paul Smits; Jacques W M Lenders
Sympathoinhibition by atorvastatin in hypertensive patients.
Circulation journal : official journal of the Japanese Circulation Society 2010;74(12):2622-6.
2010: Marc E R Gomes; Alexandra Mulder; Louise Bellersen; Freek W A Verheugt; Paul Smits; Cees J Tack
Alpha-receptor blockade improves muscle perfusion and glucose uptake in heart failure.
European journal of heart failure 2010;12(10):1061-6.
2010: Patrick Meijer; Constantijn W Wouters; Petra H H van den Broek; Maarten de Rooij; Gert Jan Scheffer; Paul Smits; Gerard A Rongen
Upregulation of ecto-5'-nucleotidase by rosuvastatin increases the vasodilator response to ischemia.
Hypertension 2010;56(4):722-7.
2010: Jan T Groothuis; Dick H J Thijssen; Gerard A Rongen; jaap deinum; Alexander Hessel Jan Danser; Alexander C H Geurts; Paul Smits; Maria T E Hopman
Angiotensin II contributes to the increased baseline leg vascular resistance in spinal cord-injured individuals.
Journal of hypertension 2010;28(10):2094-101.
2010: A J Rennings; Paul Smits; M W Stewart; Cees J Tack
Autonomic neuropathy predisposes to rosiglitazone-induced vascular leakage in insulin-treated patients with type 2 diabetes: a randomised, controlled trial on thiazolidinedione-induced vascular leakage.
Diabetologia 2010;53(9):1856-66.
2010: Marc E Gomes; Wim R M Aengevaeren; Jacques W Lenders; Freek W Verheugt; Paul Smits; Cees J Tack
Improving myocardial perfusion by percutaneous coronary intervention reduces central sympathetic activity in stable angina.
Clinical cardiology 2010;33(6):E16-21.
2010: Alexander J Rennings; Patrick Meijer; Dominique J van Uden; Cees J Tack; Paul Smits; Otto Boerman; Wim J Oyen; Gerard A Rongen
Rosiglitazone reduces ischaemia-reperfusion injury in patients with the metabolic syndrome.
European heart journal 2010;31(8):983.
2010: Jan T Groothuis; Gerard A Rongen; jaap deinum; Peter Pickkers; Alexander Hessel Jan Danser; Alexander C H Geurts; Paul Smits; Maria T E Hopman
Sympathetic nonadrenergic transmission contributes to autonomic dysreflexia in spinal cord-injured individuals.
Hypertension 2010;55(3):636-43.
2010: Marc E Gomes; Paul Smits; Freek W Verheugt; Cees J Tack
Effect of PCI on inflammatory markers, adiponectin and insulin resistance.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 2010;5(7):838-40.
2009: Marlies Bosselaar; Hanneke Boon; Luc van Loon; Petra H H van den Broek; Paul Smits; Cees J Tack
Intra-arterial AICA-riboside administration induces NO-dependent vasodilation in vivo in human skeletal muscle.
American journal of physiology. Endocrinology and metabolism 2009;297(3):E759-66.
2009: Patrick Meijer; Wim J G Oyen; Douwe Dekker; Petra H H van den Broek; Constatijn W Wouters; Otto Boerman; Gert Jan Scheffer; Paul Smits; Gerard A Rongen
Rosuvastatin increases extracellular adenosine formation in humans in vivo: a new perspective on cardiovascular protection.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(6):963-8.
2009: Miriam Kooijman; Gerard A Rongen; Paul Smits; H J M van Kuppevelt; Maria T E Hopman
The role of the alpha-adrenergic receptor in the leg vasoconstrictor response to orthostatic stress.
Acta physiologica (Oxford, England) 2009;195(3):357-66.
2009: Niels P Riksen; Gerard A Rongen; Paul Smits
Acute and long-term cardiovascular effects of coffee: implications for coronary heart disease.
Pharmacology & therapeutics 2009;121(2):185-91.
2009: Martijn G H Van Oijen; Christine Barthélémy; Marcel J R Janssen; Etienne Joiris; Wilbert H M Peters; Robert J F Laheij; Paul Smits; Pascal Odou; Jan B M J Jansen
Effect of genetic polymorphisms in UDP-glucuronosyltransferase 1A6 (UGT1A6) on acetylsalicylic acid metabolism in healthy female volunteers.
Pharmacology 2009;83(4):237-42.
2008: Bart P Ramakers; P Pickkers; A Deussen; Gerard A Rongen; P van den Broek; J G van der Hoeven; Paul Smits; Niels P Riksen
Measurement of the endogenous adenosine concentration in humans in vivo: methodological considerations.
Current drug metabolism 2008;9(8):679-85.
2008: Niels P Riksen; Barbara Franke; Petra van den Broek; Marlies Naber; Paul Smits; Gerard A Rongen
The 22G>A polymorphism in the adenosine deaminase gene impairs catalytic function but does not affect reactive hyperaemia in humans in vivo.
Pharmacogenetics and genomics 2008;18(10):843-6.
2008: Niels P Riksen; Gerard A Rongen; Derek Yellon; Paul Smits
Human in vivo research on the vascular effects of adenosine.
European journal of pharmacology 2008;585(2-3):220-7.
2008: Dick H J Thijssen; Miriam Kooijman; Patricia C E de Groot; Michiel W P Bleeker; Paul Smits; Daniel J Green; Maria T E Hopman
Endothelium-dependent and -independent vasodilation of the superficial femoral artery in spinal cord-injured subjects.
Journal of applied physiology (Bethesda, Md. : 1985) 2008;104(5):1387-93.
2008: Alexandra H Mulder; Arie P J van Dijk; Paul Smits; Cees J Tack
Real-time contrast imaging: a new method to monitor capillary recruitment in human forearm skeletal muscle.
Microcirculation (New York, N.Y. : 1994) 2008;15(3):203-13.
2008: B J J W Schouwenberg; Bart A Veldman; Wilko Spiering; Marieke Coenen; Barbara Franke; Cees J Tack; Bastiaan E De Galan; Paul Smits
The Arg16Gly variant of the beta2-adrenergic receptor predisposes to hypoglycemia unawareness in type 1 diabetes mellitus.
Pharmacogenetics and genomics 2008;18(4):369-72.
2008: P Meijer; C W Wouters; Petra H H van den Broek; G J Scheffer; Niels P Riksen; Paul Smits; Gerard A Rongen
Dipyridamole enhances ischaemia-induced reactive hyperaemia by increased adenosine receptor stimulation.
British journal of pharmacology 2008;153(6):1169-76.
2008: Miriam Kooijman; Dick H J Thijssen; Patricia C E de Groot; Michiel W P Bleeker; H J M van Kuppevelt; Daniel J Green; Gerard A Rongen; Paul Smits; Maria T E Hopman
Flow-mediated dilatation in the superficial femoral artery is nitric oxide mediated in humans.
The Journal of physiology 2008;586(4):1137-45.
2008: Dick H J Thijssen; Gerard A Rongen; Paul Smits; Maria T E Hopman
Physical (in)activity and endothelium-derived constricting factors: overlooked adaptations.
The Journal of physiology 2008;586(2):319-24.
2007: Miriam Kooijman; M de Hoog; Gerard A Rongen; H J M van Kuppevelt; Paul Smits; Maria T E Hopman
Local vasoconstriction in spinal cord-injured and able-bodied individuals.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;103(3):1070-7.
2007: Dick H J Thijssen; Gerard A Rongen; Arie van Dijk; Paul Smits; Maria T E Hopman
Enhanced endothelin-1-mediated leg vascular tone in healthy older subjects.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;103(3):852-7.
2007: Niels P Riksen; Barbara Franke; Petra van den Broek; Paul Smits; Gerard A Rongen
The 1976C>T polymorphism in the adenosine A2A receptor gene does not affect the vasodilator response to adenosine in humans in vivo.
Pharmacogenetics and genomics 2007;17(7):551-4.
2007: Dick H J Thijssen; Patricia C E de Groot; Paul Smits; Maria T E Hopman
Vascular adaptations to 8-week cycling training in older men.
Acta physiologica (Oxford, England) 2007;190(3):221-8.
2007: Niels P Riksen; Marlies Bosselaar; Stephan J L Bakker; Robert J Heine; Gerard A Rongen; Cees J Tack; Paul Smits
Acute elevation of plasma non-esterified fatty acids increases pulse wave velocity and induces peripheral vasodilation in humans in vivo.
Clinical science (London, England : 1979) 2007;113(1):33-40.
2007: Lucas T G J van Eijk; Mirrin J Dorresteijn; Paul Smits; Johannes G van der Hoeven; Mihai G Netea; Peter Pickkers
Gender differences in the innate immune response and vascular reactivity following the administration of endotoxin to human volunteers.
Critical care medicine 2007;35(6):1464-9.
2007: Niels P Riksen; Barbara Franke; Wim J G Oyen; George F Borm; Petra van den Broek; Otto Boerman; Paul Smits; Gerard A Rongen
Augmented hyperaemia and reduced tissue injury in response to ischaemia in subjects with the 34C > T variant of the AMPD1 gene.
European heart journal 2007;28(9):1085-91.
2007: Miriam Kooijman; Fleur Poelkens; Gerard A Rongen; Paul Smits; Maria T E Hopman
Leg blood flow measurements using venous occlusion plethysmography during head-up tilt.
Clinical autonomic research : official journal of the Clinical Autonomic Research Society 2007;17(2):106-11.
2007: Niels P Riksen; Gerard A Rongen; Paul Smits; P L C M van Riel; Pilar Barrera
Effect of the 34C>T variant in the AMPD1 gene on the clinical response to methotrexate in patients with rheumatoid arthritis: comment on the article by Wessels et al.
Arthritis and rheumatism 2007;56(2):694; author reply 694-5.
2007: Dick H J Thijssen; Reinier Ellenkamp; Miriam Kooijman; Peter Pickkers; Gerard A Rongen; Maria T E Hopman; Paul Smits
A causal role for endothelin-1 in the vascular adaptation to skeletal muscle deconditioning in spinal cord injury.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(2):325-31.
2006: Bart P Ramakers; Niels P Riksen; Johannes G van der Hoeven; Paul Smits; Peter Pickkers
Protective effects of adenosine A2A agonist during hemorrhagic shock: a simple intervention may result in a complex response.
Critical care medicine 2006;34(12):3059; author reply 3059-60.
2006: Dick H J Thijssen; Joost Vos; Caroline Verseyden; Anton-Jan van Zonneveld; Paul Smits; Fred C G J Sweep; Maria T E Hopman; Hetty C de Boer
Haematopoietic stem cells and endothelial progenitor cells in healthy men: effect of aging and training.
Aging cell 2006;5(6):495-503.
2006: Dick H J Thijssen; Patricia de Groot; Miriam Kooijman; Paul Smits; Maria T E Hopman
Sympathetic nervous system contributes to the age-related impairment of flow-mediated dilation of the superficial femoral artery.
American journal of physiology. Heart and circulatory physiology 2006;291(6):H3122-9.
2006: Mirrin J Dorresteijn; Paul Smits; Hans G van der Hoeven; Peter Pickkers
Role of potassium channel blockade in the treatment of sepsis-induced vascular hyporeactivity.
Critical care medicine 2006;34(11):2867-8; author reply 2868-9.
2006: Petra J van Gurp; Jacques J Willemsen; Jacques W M Lenders; H Alec Ross; C G J Sweep; Paul Smits; Cees J Tack
Forearm vasoconstrictor response in uncomplicated type 1 diabetes mellitus.
European journal of clinical investigation 2006;36(10):674-81.
2006: Bastiaan E De Galan; B J J W Schouwenberg; Cees J Tack; Paul Smits
Pathophysiology and management of recurrent hypoglycaemia and hypoglycaemia unawareness in diabetes.
The Netherlands journal of medicine 2006;64(8):269-79.
2006: Niels P Riksen; Zhigang Zhou; Wim J G Oyen; Rogier Jaspers; Bart P Ramakers; Rene M H J Brouwer; Otto Boerman; Neil Steinmetz; Paul Smits; Gerard A Rongen
Caffeine prevents protection in two human models of ischemic preconditioning.
Journal of the American College of Cardiology 2006;48(4):700-7.
2006: Peter Pickkers; Mirrin J Dorresteijn; Martijn P W J M Bouw; Johannes G van der Hoeven; Paul Smits
In vivo evidence for nitric oxide-mediated calcium-activated potassium-channel activation during human endotoxemia.
Circulation 2006;114(5):414-21.
2006: Bastiaan E De Galan; Pieter De Mol; Lianne Wennekes; B J J W Schouwenberg; Paul Smits
Preserved sensitivity to beta2-adrenergic receptor agonists in patients with type 1 diabetes mellitus and hypoglycemia unawareness.
The Journal of clinical endocrinology and metabolism 2006;91(8):2878-81.
2006: Suzanne Heemskerk; Peter Pickkers; Martijn P W J M Bouw; Annelies Draisma; Johannes G van der Hoeven; Wilbert H M Peters; Paul Smits; Frans G M Russel; Rosalinde Masereeuw
Upregulation of renal inducible nitric oxide synthase during human endotoxemia and sepsis is associated with proximal tubule injury.
Clinical journal of the American Society of Nephrology : CJASN 2006;1(4):853-62.
2006: Bart P Ramakers; Niels P Riksen; Gerard A Rongen; Johannes G van der Hoeven; Paul Smits; Peter Pickkers
The effect of adenosine receptor agonists on cytokine release by human mononuclear cells depends on the specific Toll-like receptor subtype used for stimulation.
Cytokine 2006;35(1-2):95-9.
2006: Cees J Tack; Paul Smits
Thiazolidinedione derivatives in type 2 diabetes mellitus.
The Netherlands journal of medicine 2006;64(6):166-74.
2006: Niels P Riksen; Paul Smits; Gerard A Rongen
The nonspecific anti-inflammatory therapy with methotrexate for patients with chronic heart failure.
American heart journal 2006;151(5):e5; author reply e6-7.
2006: Lucas T G J van Eijk; Arjan Nooteboom; Thijs Hendriks; Tom Sprong; Mihai G Netea; Paul Smits; Johannes G van der Hoeven; Peter Pickkers
Plasma obtained during human endotoxemia increases endothelial albumin permeability in vitro.
Shock (Augusta, Ga.) 2006;25(4):358-62.
2006: Dick H J Thijssen; Reinier Ellenkamp; Paul Smits; Maria T E Hopman
Rapid vascular adaptations to training and detraining in persons with spinal cord injury.
Archives of physical medicine and rehabilitation 2006;87(4):474-81.
2006: Niels P Riksen; Pilar Barrera; Petra H H van den Broek; P L C M van Riel; Paul Smits; Gerard A Rongen
Methotrexate modulates the kinetics of adenosine in humans in vivo.
Annals of the rheumatic diseases 2006;65(4):465-70.
2006: Alexander J M Rennings; Paul Smits; Murray W Stewart; Cees J Tack
Fluid retention and vascular effects of rosiglitazone in obese, insulin-resistant, nondiabetic subjects.
Diabetes care 2006;29(3):581-7.
2006: B J J W Schouwenberg; Saskia J Rietjens; Paul Smits; Bastiaan E De Galan
Effect of sex on the cardiovascular response to adrenaline in humans.
Journal of cardiovascular pharmacology 2006;47(1):155-7.
2005: Peter Pickkers; Tom Sprong; Lucas van Eijk; Hans van der Hoeven; Paul Smits; Marcel van Deuren
Vascular endothelial growth factor is increased during the first 48 hours of human septic shock and correlates with vascular permeability.
Shock (Augusta, Ga.) 2005;24(6):508-12.
2005: Sylvia Notenboom; David S Miller; Leon H Kuik; Paul Smits; Frans G M Russel; Rosalinde Masereeuw
Short-term exposure of renal proximal tubules to gentamicin increases long-term multidrug resistance protein 2 (Abcc2) transport function and reduces nephrotoxicant sensitivity.
The Journal of pharmacology and experimental therapeutics 2005;315(2):912-20.
2005: Michiel W P Bleeker; Patricia C E de Groot; Gerard A Rongen; Jörn Rittweger; Dieter Felsenberg; Paul Smits; Maria T E Hopman
Vascular adaptation to deconditioning and the effect of an exercise countermeasure: results of the Berlin Bed Rest study.
Journal of applied physiology (Bethesda, Md. : 1985) 2005;99(4):1293-300.
2005: Alexandra H Mulder; Cees J Tack; André J Olthaar; Paul Smits; Fred C G J Sweep; Remko R Bosch
Adrenergic receptor stimulation attenuates insulin-stimulated glucose uptake in 3T3-L1 adipocytes by inhibiting GLUT4 translocation.
American journal of physiology. Endocrinology and metabolism 2005;289(4):E627-33.
2005: Thomas K A Wierema; Alphons J H M Houben; Abraham A Kroon; Cornelis T Postma; Derk Koster; Jos M A van Engelshoven; Paul Smits; Peter W de Leeuw
Mechanisms of adenosine-induced renal vasodilatation in hypertensive patients.
Journal of hypertension 2005;23(9):1731-6.
2005: Richard Engbersen; Rosalinde Masereeuw; Miriam A van Gestel; Elise M J van der Logt; Paul Smits; Frans G M Russel
Glibenclamide depletes ATP in renal proximal tubular cells by interfering with mitochondrial metabolism.
British journal of pharmacology 2005;145(8):1069-75.
2005: Niels P Riksen; Egidia E M van Ginneken; Petra H H van den Broek; Paul Smits; Gerard A Rongen
In vivo evidence against a role for adenosine in the exercise pressor reflex in humans.
Journal of applied physiology (Bethesda, Md. : 1985) 2005;99(2):522-7.
2005: Lambertus J H Van Tits; E Arioglu-Oral; C G J Sweep; Paul Smits; Anton F H Stalenhoef; Cees J Tack
Anti-inflammatory effects of troglitazone in nondiabetic obese subjects independent of changes in insulin sensitivity.
The Netherlands journal of medicine 2005;63(7):250-5.
2005: Niels P Riksen; Wim J G Oyen; Bart P Ramakers; Petra H H van den Broek; Richard Engbersen; Otto Boerman; Paul Smits; Gerard A Rongen
Oral therapy with dipyridamole limits ischemia-reperfusion injury in humans.
Clinical pharmacology and therapeutics 2005;78(1):52-9.
2005: C T Postma; S M J Maessen; Theo Thien; Paul Smits
The effect of arginine vasopressin on endothelin production in the human forearm vascular bed.
The Netherlands journal of medicine 2005;63(6):199-204.
2005: Michiel W P Bleeker; Miriam Kooijman; Gerard A Rongen; Maria T E Hopman; Paul Smits
Preserved contribution of nitric oxide to baseline vascular tone in deconditioned human skeletal muscle.
The Journal of physiology 2005;565(Pt 2):685-94.
2005: Gerald Vervoort; B A J Veldman; Jo H M Berden; Paul Smits; Jack F M Wetzels
Glomerular hyperfiltration in type 1 diabetes mellitus results from primary changes in proximal tubular sodium handling without changes in volume expansion.
European journal of clinical investigation 2005;35(5):330-6.
2005: Tanya M Bisseling; Alfons C Wouterse; Eric A P Steegers; Lammy D Elving; Frans G M Russel; Paul Smits
Dysfunction of the cyclo-oxygenase pathway in the foetoplacental circulation in Type 1 diabetes mellitus.
Diabetic medicine : a journal of the British Diabetic Association 2005;22(4):503-6.
2005: Lucas T G J van Eijk; Peter Pickkers; Paul Smits; Wim van den Broek; Martijn P W J M Bouw; Johannes G van der Hoeven
Microvascular permeability during experimental human endotoxemia: an open intervention study.
Critical care (London, England) 2005;9(2):R157-64.
2005: Michiel W P Bleeker; Patricia C E de Groot; Fleur Poelkens; Gerard A Rongen; Paul Smits; Maria T E Hopman
Vascular adaptation to 4 wk of deconditioning by unilateral lower limb suspension.
American journal of physiology. Heart and circulatory physiology 2005;288(4):H1747-55.
2005: T G W Speel; Lambertus A L M Kiemeney; Theo Thien; Paul Smits; E J H Meuleman
Long-term effect of inhibition of the angiotensin-converting enzyme (ACE) on cavernosal perfusion in men with atherosclerotic erectile dysfunction: a pilot study.
The journal of sexual medicine 2005;2(2):207-12.
2005: Tanya M Bisseling; Marieke G Versteegen; Selina van der Wal; Jenny J H Copius Peereboom-Stegeman; Joop M P M Borggreven; Eric A P Steegers; Jeroen A W M van der Laak; Frans G M Russel; Paul Smits
Impaired KATP channel function in the fetoplacental circulation of patients with type 1 diabetes mellitus.
American journal of obstetrics and gynecology 2005;192(3):973-9.
2005: B A J Veldman; Gerald Vervoort; Henk Blom; Paul Smits
Reduced plasma total homocysteine concentrations in Type 1 diabetes mellitus is determined by increased renal clearance.
Diabetic medicine : a journal of the British Diabetic Association 2005;22(3):301-5.
2005: Dick H J Thijssen; Michiel W P Bleeker; Paul Smits; Maria T E Hopman
Reproducibility of blood flow and post-occlusive reactive hyperaemia as measured by venous occlusion plethysmography.
Clinical science (London, England : 1979) 2005;108(2):151-7.
2005: Gerard A Rongen; Wim J G Oyen; Bart P Ramakers; Niels P Riksen; Otto Boerman; Neil Steinmetz; Paul Smits
Annexin A5 scintigraphy of forearm as a novel in vivo model of skeletal muscle preconditioning in humans.
Circulation 2005;111(2):173-8.
2005: Mirrin J Dorresteijn; Lucas T G J van Eijk; Mihai G Netea; Paul Smits; Johannes G van der Hoeven; Peter Pickkers
Iso-osmolar prehydration shifts the cytokine response towards a more anti-inflammatory balance in human endotoxemia.
Journal of endotoxin research 2005;11(5):287-93.
2005: Niels P Riksen; Gerard A Rongen; Henk J Blom; Godfried H J Boers; Paul Smits
Reduced adenosine receptor stimulation as a pathogenic factor in hyperhomocysteinemia.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2005;43(10):1001-6.
2005: Niels P Riksen; Gerard A Rongen; Godfried H J Boers; Henk J Blom; Petra H H van den Broek; Paul Smits
Enhanced cellular adenosine uptake limits adenosine receptor stimulation in patients with hyperhomocysteinemia.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(1):109-14.
2004: Chantal P Bleeker-Rovers; Andre J A M van der Ven; Bert Zomer; Lioe-Fee de Geus-Oei; Paul Smits; Frans H M Corstens; Peter P Koopmans; Wim J G Oyen
F-18-fluorodeoxyglucose positron emission tomography for visualization of lipodystrophy in HIV-infected patients.
AIDS (London, England) 2004;18(18):2430-2.
2004: Niels P Riksen; Paul Smits; Gerard A Rongen
Ischaemic preconditioning: from molecular characterisation to clinical application--part II.
The Netherlands journal of medicine 2004;62(11):409-23.
2004: Lucas T G J van Eijk; Peter Pickkers; Paul Smits; Martijn P W J M Bouw; Johannes G van der Hoeven
Severe vagal response after endotoxin administration in humans.
Intensive care medicine 2004;30(12):2279-81.
2004: Niels P Riksen; Paul Smits; Gerard A Rongen
Ischaemic preconditioning: from molecular characterisation to clinical application--part I.
The Netherlands journal of medicine 2004;62(10):353-63.
2004: Evertine J Abbink; Pieter S van der Wal; C G J Sweep; Paul Smits; Cees J Tack
Compared to glibenclamide, repaglinide treatment results in a more rapid fall in glucose level and beta-cell secretion after glucose stimulation.
Diabetes/metabolism research and reviews 2004;20(6):466-71.
2004: Peter Pickkers; Aarnout J Jansen Van Rosendaal; Johannes G van der Hoeven; Paul Smits
Activation of the ATP-dependent potassium channel attenuates norepinephrine-induced vasoconstriction in the human forearm.
Shock (Augusta, Ga.) 2004;22(4):320-5.
2004: B A J Veldman; M Waanders; Paul Smits
Pharmacodynamics of L-NMMA in type 1 diabetes patients and control subjects.
Journal of cardiovascular pharmacology 2004;44(2):231-4.
2004: Tanya M Bisseling; Eva Maria Roes; Maarten T M Raijmakers; Eric A P Steegers; Wilbert H M Peters; Paul Smits
N-acetylcysteine restores nitric oxide-mediated effects in the fetoplacental circulation of preeclamptic patients.
American journal of obstetrics and gynecology 2004;191(1):328-33.
2004: Tanya M Bisseling; Eric A P Steegers; J J M van den Heuvel; Helene Siero; Femke M van de Water; A J Walker; Régine P M Steegers-Theunissen; Paul Smits; Frans G M Russel
Placental folate transport and binding are not impaired in pregnancies complicated by fetal growth restriction.
Placenta 2004;25(6):588-93.
2004: Sylvia Notenboom; David S Miller; Paul Smits; Frans G M Russel; Rosalinde Masereeuw
Involvement of guanylyl cyclase and cGMP in the regulation of Mrp2-mediated transport in the proximal tubule.
American journal of physiology. Renal physiology 2004;287(1):F33-8.
2004: Michiel W P Bleeker; Maria T E Hopman; Gerard A Rongen; Paul Smits
Unilateral lower limb suspension can cause deep venous thrombosis.
American journal of physiology. Regulatory, integrative and comparative physiology 2004;286(6):R1176-7.
2004: Peter Pickkers; Astrid Hoedemaekers; Mihai G Netea; B E de Galan; Paul Smits; Johannes G van der Hoeven; Marcel van Deuren
Hypothesis: Normalisation of cytokine dysbalance explains the favourable effects of strict glucose regulation in the critically ill.
The Netherlands journal of medicine 2004;62(5):143-50.
2004: Bastiaan E De Galan; Cees J Tack; Jacques J Willemsen; C G J Sweep; Paul Smits; Jacques W M Lenders
Plasma metanephrine levels are decreased in type 1 diabetic patients with a severely impaired epinephrine response to hypoglycemia, indicating reduced adrenomedullary stores of epinephrine.
The Journal of clinical endocrinology and metabolism 2004;89(5):2057-61.
2004: Peter Bijlstra; Egidia E M van Ginneken; Marc Huls; Rob van Dijk; Paul Smits; Gerard A Rongen
Glyburide inhibits dipyridamole-induced forearm vasodilation but not adenosine-induced forearm vasodilation.
Clinical pharmacology and therapeutics 2004;75(3):147-56.
2004: Egidia E M van Ginneken; P Meijer; N Verkaik; Paul Smits; Gerard A Rongen
ATP-induced vasodilation in human skeletal muscle.
British journal of pharmacology 2004;141(5):842-50.
2004: Miranda Bartels-Stringer; Linda Terlunen; Helene Siero; Frans G M Russel; Paul Smits; Cornelis Kramers
Preserved vascular reactivity of rat renal arteries after cold storage.
Cryobiology 2004;48(1):95-8.
2004: Egidia E M van Ginneken; Hal Drooglever-Fortuyn; Paul Smits; Gerard A Rongen
The influence of diazepam and midazolam on adenosine-induced forearm vasodilation in humans.
Journal of cardiovascular pharmacology 2004;43(2):276-80.
2003: Miriam Kooijman; Gerard A Rongen; Paul Smits; Maria T E Hopman
Preserved alpha-adrenergic tone in the leg vascular bed of spinal cord-injured individuals.
Circulation 2003;108(19):2361-7.
2003: Bastiaan E De Galan; Saskia J Rietjens; Cees J Tack; Sieberen van der Werf; C G J Sweep; Jacques W M Lenders; Paul Smits
Antecedent adrenaline attenuates the responsiveness to but not the release of counterregulatory hormones during subsequent hypoglycemia.
The Journal of clinical endocrinology and metabolism 2003;88(11):5462-7.
2003: Tanya M Bisseling; Alfons C Wouterse; Eric A P Steegers; Lammy D Elving; Frans G M Russel; Paul Smits
Nitric oxide-mediated vascular tone in the fetal placental circulation of patients with type 1 diabetes mellitus.
Placenta 2003;24(10):974-8.
2003: Niels P Riksen; Gerard A Rongen; Henk J Blom; Frans G M Russel; Godfried H J Boers; Paul Smits
Potential role for adenosine in the pathogenesis of the vascular complications of hyperhomocysteinemia.
Cardiovascular research 2003;59(2):271-6.
2003: Bastiaan E De Galan; Cees J Tack; Jacques W M Lenders; Jos A Lutterman; Paul Smits
Effect of 2 weeks of theophylline on glucose counterregulation in patients with type 1 diabetes and unawareness of hypoglycemia.
Clinical pharmacology and therapeutics 2003;74(1):77-84.
2003: Romana T Netea; Jacques W M Lenders; Paul Smits; Theo Thien
Both body and arm position significantly influence blood pressure measurement.
Journal of human hypertension 2003;17(7):459-62.
2003: Bastiaan E De Galan; Mihai G Netea; Paul Smits; J W M Van Der Meer
Hypoglycaemia downregulates endotoxin-induced production of tumour necrosis factor-alpha, but does not affect IL-1beta, IL-6, or IL-10.
Cytokine 2003;22(3-4):71-6.
2003: Peter Pickkers; Frans G M Russel; Theo Thien; Alun HUGHES; Paul Smits
Only weak vasorelaxant properties of loop diuretics in isolated resistance arteries from man, rat and guinea pig.
European journal of pharmacology 2003;466(3):281-7.
2003: Niels P Riksen; Bart Ellenbroek; Alexander R Cools; Helene Siero; Gerard A Rongen; Bart W Smits; Frans G M Russel; Paul Smits
Stress susceptibility as a determinant of endothelium-dependent vascular reactivity in rat mesenteric arteries.
Journal of cardiovascular pharmacology 2003;41(4):625-31.
2003: Romana T Netea; Jacques W M Lenders; Paul Smits; Theo Thien
Influence of body and arm position on blood pressure readings: an overview.
Journal of hypertension 2003;21(2):237-41.
2003: Roger J Legtenberg; Ralph J F Houston; Paul Smits; Berend Oeseburg
Pinacidil-induced opening, like glibenclamide-induced closure of cardiac KATP channels, protects cardiac function against ischemia in isolated, working, erythrocyte perfused rat hearts.
Advances in experimental medicine and biology 2003;530():519-26.
2002: Peter Pickkers; Mihai G Netea; Jos W M van der Meer; Paul Smits
TNFalpha and IL-1beta exert no direct vasoactivity in human isolated resistance arteries.
Cytokine 2002;20(5):244-6.
2002: Bart W Smits; Helene Siero; Bart Ellenbroek; Niels P Riksen; Alexander R Cools; Joop M P M Borggreven; Gerard A Rongen; Frans G M Russel; Paul Smits
Stress susceptibility as a determinant of the response to adrenergic stimuli in mesenteric resistance arteries of the rat.
Journal of cardiovascular pharmacology 2002;40(5):678-83.
2002: Stan H M van Uum; Alphons J H M Houben; Ad R M M Hermus; Abraham A Kroon; Brian R Walker; C G J Sweep; Paul Smits; Peter W de Leeuw; Jacques W M Lenders
Acute intrarenal administration of cortisol has no effect on renal blood flow in hypertensive individuals.
Journal of hypertension 2002;20(11):2275-83.
2002: B A J Veldman; Wilko Spiering; Peter A Doevendans; Gerald Vervoort; Abraham A Kroon; Peter W de Leeuw; Paul Smits
The Glu298Asp polymorphism of the NOS 3 gene as a determinant of the baseline production of nitric oxide.
Journal of hypertension 2002;20(10):2023-7.
2002: Roger J Legtenberg; Gerard A Rongen; Ralph J F Houston; Berend Oeseburg; Paul Smits
The role of myocardial KATP-channel blockade in the protective effects of glibenclamide against ischaemia in the rat heart.
Pharmacology & toxicology 2002;91(2):51-6.
2002: Gerald Vervoort; Jack F M Wetzels; Jos A Lutterman; Bert Bravenboer; Jo H M Berden; Paul Smits
Atrial natriuretic peptide-induced microalbuminuria is associated with endothelial dysfunction in noncomplicated type 1 diabetes patients.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2002;40(1):9-15.
2002: Egidia E M van Ginneken; Gerard A Rongen; Frans G M Russel; Paul Smits
Diadenosine pentaphosphate vasodilates the forearm vascular bed: inhibition by theophylline and augmentation by dipyridamole.
Clinical pharmacology and therapeutics 2002;71(6):448-56.
2002: Roger J Legtenberg; Ralph J F Houston; Berend Oeseburg; Paul Smits
Physiological insulin concentrations protect against ischemia-induced loss of cardiac function in rats.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2002;132(1):161-7.
2002: Gerard A Rongen; Johannes P Van Dijk; Egidia E M van Ginneken; Dick F Stegeman; Paul Smits; Machiel J Zwarts
Repeated ischaemic isometric exercise increases muscle fibre conduction velocity in humans: involvement of Na(+)-K(+)-ATPase.
The Journal of physiology 2002;540(Pt 3):1071-8.
2002: Roger J Legtenberg; Ralph J F Houston; Berend Oeseburg; Paul Smits
Metformin improves cardiac functional recovery after ischemia in rats.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2002;34(4):182-5.
2002: Evertine J Abbink; Bastiaan E De Galan; Egidia E M van Ginneken; Aarnout Jansen van Rosendaal; Paul Smits
No vasodilator response to low-dose heparin in the forearm skeletal-muscle vascular bed.
European journal of clinical pharmacology 2002;58(1):7-10.
2002: Evertine J Abbink; Annabel J Walker; Henk A van der Sluijs; Cees J Tack; Paul Smits
No role of calcium- and ATP-dependent potassium channels in insulin-induced vasodilation in humans in vivo.
Diabetes/metabolism research and reviews 2002;18(2):143-8.
2002: Evertine J Abbink; Hub Wollersheim; PM Netten; Frans G M Russel; Jos A Lutterman; Paul Smits
Microcirculatory effects of KATP channel blockade by sulphonylurea derivatives in humans.
European journal of clinical investigation 2002;32(3):163-71.
2002: Bastiaan E De Galan; Cees J Tack; Jacques W M Lenders; Jaco W Pasman; Lammy D Elving; Frans G M Russel; Jos A Lutterman; Paul Smits
Theophylline improves hypoglycemia unawareness in type 1 diabetes.
Diabetes 2002;51(3):790-6.
2002: Evertine J Abbink; Peter Pickkers; A Jansen van Rosendaal; Jos A Lutterman; Cees J Tack; Frans G M Russel; Paul Smits
Vascular K(ATP) channel blockade by glibenclamide, but not by acarbose, in patients with Type II diabetes.
Clinical science (London, England : 1979) 2002;102(3):307-14.
2002: Sylvia Notenboom; David S Miller; Paul Smits; Frans G M Russel; Rosalinde Masereeuw
Role of NO in endothelin-regulated drug transport in the renal proximal tubule.
American journal of physiology. Renal physiology 2002;282(3):F458-64.
2002: Gerald Vervoort; Lammy D Elving; Jack F M Wetzels; Jos A Lutterman; Paul Smits; Jan Joep H H M de Pont; Jo H M Berden
Sodium-lithium countertransport is increased in normoalbuminuric type 1 diabetes but is not related to other risk factors for microangiopathy.
European journal of clinical investigation 2002;32(2):93-9.
2002: Evertine J Abbink; Peter Pickkers; A Jansen van Rosendaal; Jos A Lutterman; Cees J Tack; Frans G M Russel; Paul Smits
Vascular effects of glibenclamide vs. glimepiride and metformin in Type 2 diabetic patients.
Diabetic medicine : a journal of the British Diabetic Association 2002;19(2):136-43.
2002: Stan H M van Uum; Brian R Walker; Ad R M M Hermus; C G J Sweep; Paul Smits; Peter W de Leeuw; Jacques W M Lenders
Effect of glycyrrhetinic acid on 11 beta-hydroxysteroid dehydrogenase activity in normotensive and hypertensive subjects.
Clinical science (London, England : 1979) 2002;102(2):203-11.
2002: Gerben B Keijzers; Bastiaan E De Galan; Cees J Tack; Paul Smits
Caffeine can decrease insulin sensitivity in humans.
Diabetes care 2002;25(2):364-9.
2002: Roger J Legtenberg; Ralph J F Houston; Arend Heerschap; Berend Oeseburg; Paul Smits
Glibenclamide attenuates ischemia-induced acidosis and loss of cardiac function in rats.
European journal of pharmacology 2002;434(1-2):35-42.
2001: Evertine J Abbink; Hub Wollersheim; PM Netten; Paul Smits
Reproducibility of skin microcirculatory measurements in humans, with special emphasis on capillaroscopy.
Vascular medicine (London, England) 2001;6(4):203-10.
2001: Roger J Legtenberg; Ralph J F Houston; Berend Oeseburg; Paul Smits
Effects of sulfonylurea derivatives on ischemia-induced loss of function in the isolated rat heart.
European journal of pharmacology 2001;419(1):85-92.
2001: Marie-Jose J Pouwels; J R Jacobs; Paul Span; Jos A Lutterman; Paul Smits; Cees J Tack
Short-term glucosamine infusion does not affect insulin sensitivity in humans.
The Journal of clinical endocrinology and metabolism 2001;86(5):2099-103.
2001: Peter Pickkers; Alun HUGHES; Frans G M Russel; Theo Thien; Paul Smits
In vivo evidence for K(Ca) channel opening properties of acetazolamide in the human vasculature.
British journal of pharmacology 2001;132(2):443-50.
2001: Evertine J Abbink; Cees J Tack; Paul Smits
Vascular effects of metabolic inhibition by 2-deoxy-D-glucose in humans.
Journal of cardiovascular pharmacology 2001;37(1):94-100.
2000: Rosalinde Masereeuw; A P van Pelt; Sandra Van Os; Peter H G M Willems; Paul Smits; Frans G M Russel
Probenecid interferes with renal oxidative metabolism: a potential pitfall in its use as an inhibitor of drug transport.
British journal of pharmacology 2000;131(1):57-62.
2000: Richard Engbersen; MM Moons; Alfons C Wouterse; Henry B P M Dijkman; Cornelis Kramers; Paul Smits; Frans G M Russel
Sulphonylurea drugs reduce hypoxic damage in the isolated perfused rat kidney.
British journal of pharmacology 2000;130(7):1678-84.
2000: E J van den Berg; Frans G M Russel; Rob P Bos; Paul Smits; Cornelis Kramers
[Lavage almost never indicated after an autointoxication].
Nederlands tijdschrift voor geneeskunde 2000;144(20):916-8.
2000: Adrianus J van den Bergh; Cees J Tack; HJ van den Boogert; Gerald Vervoort; Paul Smits; Arend Heerschap
Assessment of human muscle glycogen synthesis and total glucose content by in vivo 13C MRS.
European journal of clinical investigation 2000;30(2):122-8.
2000: Mariëlle E A C Broeders; Yvonne F Heijdra; Paul Smits; Hans Th M Folgering; Cees Kramers
Verapamil causes decreased diaphragm endurance but no decrease of nocturnal O(2) saturation in patients with chronic obstructive pulmonary disease.
European journal of clinical pharmacology 2000;55(10):729-32.
1999: Gerald Vervoort; Jos A Lutterman; Paul Smits; J H Berden; Jack F M Wetzels
Transcapillary escape rate of albumin is increased and related to haemodynamic changes in normo-albuminuric type 1 diabetic patients.
Journal of hypertension 1999;17(12 Pt 2):1911-6.
1999: Gerald Vervoort; J F Wetzels; Jos A Lutterman; L G van Doorn; J H Berden; Paul Smits
Elevated skeletal muscle blood flow in noncomplicated type 1 diabetes mellitus: role of nitric oxide and sympathetic tone.
Hypertension 1999;34(5):1080-5.
1999: P Pickkers; M van Beek; Alun HUGHES; F G Russel; Theo Thien; Paul Smits
Presence and mechanism of direct vascular effects of amiloride in humans.
Journal of cardiovascular pharmacology 1999;34(3):388-93.
1999: E J Abbink-Zandbergen; Gerald Vervoort; Cees J Tack; Jos A Lutterman; Nicolaas C Schaper; Paul Smits
The role of adenosine in insulin-induced vasodilation.
Journal of cardiovascular pharmacology 1999;34(3):374-80.
1999: B Verhage; Gerald Vervoort; C Wolkotte; Lammy D Elving; J F Wetzels; H Willems; Paul Smits; André L M Verbeek; J H Berden
Prevalence of "syndrome X" features in parents of type 1 diabetic patients with or without nephropathy.
Diabetes care 1999;22(7):1048-52.
1999: Peter Pickkers; R S Garcha; M Schachter; Paul Smits; Alun HUGHES
Inhibition of carbonic anhydrase accounts for the direct vascular effects of hydrochlorothiazide.
Hypertension 1999;33(4):1043-8.
1999: Gerald Vervoort; J F Wetzels; Jos A Lutterman; J H Berden; Theo Thien; Paul Smits
The impact of blood pressure measurement methods on the assessment of differences in blood pressure levels between patients with normoalbuminuric type 1 diabetes and healthy controls.
Journal of human hypertension 1999;13(2):117-22.
1999: Romana T Netea; Jacques W M Lenders; Paul Smits; Theo Thien
Arm position is important for blood pressure measurement.
Journal of human hypertension 1999;13(2):105-9.
1999: E M Jacobs; Gerald Vervoort; Amanda J W Branten; Ina S Klasen; Paul Smits; Jack F M Wetzels
Atrial natriuretic peptide increases albuminuria in type I diabetic patients: evidence for blockade of tubular protein reabsorption.
European journal of clinical investigation 1999;29(2):109-15.
1999: Roger J Legtenberg; Ralph J F Houston; Paul Smits; Berend Oeseburg
Hemodynamic changes caused by glibenclamide in isolated, working, erythrocyte perfused rat heart.
Advances in experimental medicine and biology 1999;471():257-63.
1998: Thomas K A Wierema; Cornelis T Postma; Alphons J H M Houben; Abraham A Kroon; Theo Thien; Paul Smits; Peter W de Leeuw
Adenosine-induced renal vasodilatation is prolonged in renal artery stenosis.
Journal of hypertension 1998;16(12 Pt 2):2109-12.
1998: Peter Pickkers; Alun HUGHES; Frans G M Russel; Theo Thien; Paul Smits
Thiazide-induced vasodilation in humans is mediated by potassium channel activation.
Hypertension 1998;32(6):1071-6.
1998: F G Russel; Stan H M van Uum; Y Tan; Paul Smits
Solid-phase extraction of 18beta-glycyrrhetinic acid from plasma and subsequent analysis by high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications 1998;710(1-2):223-6.
1998: Cees J Tack; M K Ong; Jos A Lutterman; Paul Smits
Insulin-induced vasodilatation and endothelial function in obesity/insulin resistance. Effects of troglitazone.
Diabetologia 1998;41(5):569-76.
1998: Cees J Tack; Paul Smits; P N Demacker; A F Stalenhoef
Troglitazone decreases the proportion of small, dense LDL and increases the resistance of LDL to oxidation in obese subjects.
Diabetes care 1998;21(5):796-9.
1998: Stan H M van Uum; Ad R M M Hermus; Paul Smits; Theo Thien; Jacques W M Lenders
The role of 11 beta-hydroxysteroid dehydrogenase in the pathogenesis of hypertension.
Cardiovascular research 1998;38(1):16-24.
1998: Romana T Netea; P J Bijlstra; Jacques W M Lenders; Paul Smits; Theo Thien
Influence of the arm position on intra-arterial blood pressure measurement.
Journal of human hypertension 1998;12(3):157-60.
1998: Romana T Netea; Paul Smits; Jacques W M Lenders; Theo Thien
Does it matter whether blood pressure measurements are taken with subjects sitting or supine?
Journal of hypertension 1998;16(3):263-8.
1998: Cees J Tack; Jacques W M Lenders; Jacques J Willemsen; J A van Druten; Theo Thien; Jos A Lutterman; Paul Smits
Insulin stimulates epinephrine release under euglycemic conditions in humans.
Metabolism: clinical and experimental 1998;47(3):243-9.
1998: C J Tack; Jacques W M Lenders; David S Goldstein; Jos A Lutterman; Paul Smits; Theo Thien
Haemodynamic actions of insulin.
Current opinion in nephrology and hypertension 1998;7(1):99-106.
1997: Peter Pickkers; TP Dormans; Frans G M Russel; Alun HUGHES; Theo Thien; N Schaper; Paul Smits
Direct vascular effects of furosemide in humans.
Circulation 1997;96(6):1847-52.
1997: MC Jacobs; Jacques W M Lenders; Paul Smits; J J Willemsen; Cees J Tack; Theo Thien
Long-term beta 1-adrenergic blockade restores adrenomedullary activity in primary hypertension.
Journal of cardiovascular pharmacology 1997;30(3):338-42.
1997: TP Dormans; P G Gerlag; Paul Smits
[Failing diuretics in severe chronic heart failure].
Nederlands tijdschrift voor geneeskunde 1997;141(30):1465-8.
1997: Paul Smits
Cardiovascular effects of sulphonylurea derivatives.
Diabetologia 1997;40 Suppl 2():S160-1.
1997: Gerard A Rongen; John S Floras; Jacques W M Lenders; Theo Thien; Paul Smits
Cardiovascular pharmacology of purines.
Clinical science (London, England : 1979) 1997;92(1):13-24.
1996: T P Dormans; Peter Pickkers; F G Russel; Paul Smits
Vascular effects of loop diuretics.
Cardiovascular research 1996;32(6):988-97.
1996: P J Bijlstra; J A den Arend; J A Lutterman; Frans G M Russel; Theo Thien; Paul Smits
Blockade of vascular ATP-sensitive potassium channels reduces the vasodilator response to ischaemia in humans.
Diabetologia 1996;39(12):1562-8.
1996: P J Bijlstra; Frans G M Russel; Theo Thien; J A Lutterman; Paul Smits
Effects of tolbutamide on vascular ATP-sensitive potassium channels in humans. Comparison with literature data on glibenclamide and glimepiride.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1996;28(9):512-6.
1996: Cees J Tack; A E Schefman; J L Willems; Theo Thien; J A Lutterman; Paul Smits
Direct vasodilator effects of physiological hyperinsulin-aemia in human skeletal muscle.
European journal of clinical investigation 1996;26(9):772-8.
1996: P J Bijlstra; J A Lutterman; Frans G M Russel; Theo Thien; Paul Smits
Interaction of sulphonylurea derivatives with vascular ATP-sensitive potassium channels in humans.
Diabetologia 1996;39(9):1083-90.
1996: Cees J Tack; J A Lutterman; Gerald Vervoort; Theo Thien; Paul Smits
Activation of the sodium-potassium pump contributes to insulin-induced vasodilation in humans.
Hypertension 1996;28(3):426-32.
1996: Cees J Tack; M Heeremans; Theo Thien; J A Lutterman; Paul Smits
Regional hyperinsulinemia induces vasodilation but does not modulate adrenergic responsiveness in humans.
Journal of cardiovascular pharmacology 1996;28(2):245-51.
1996: T P Dormans; J J van Meyel; P G Gerlag; Y Tan; Frans G M Russel; Paul Smits
Diuretic efficacy of high dose furosemide in severe heart failure: bolus injection versus continuous infusion.
Journal of the American College of Cardiology 1996;28(2):376-82.
1996: Paul Smits; P J Bijlstra; Frans G M Russel; J A Lutterman; Theo Thien
Cardiovascular effects of sulphonylurea derivatives.
Diabetes research and clinical practice 1996;31 Suppl():S55-9.
1996: Paul Smits
Role of potassium channels in the modulation of insulin release.
Diabetologia 1996;39(7):865-7.
1996: A van Ede; Marcel van Deuren; Paul Smits; H Wollersheim
The angio-Behçet syndrome.
The Netherlands journal of medicine 1996;49(1):30-2.
1996: P Pickkers; T Dormans; Paul Smits
Direct vasoactivity of frusemide.
Lancet 1996;347(9011):1338-9.
1996: M C Jacobs; David S Goldstein; J J Willemsen; Paul Smits; Theo Thien; Jacques W M Lenders
Differential effects of low- and high-intensity lower body negative pressure on noradrenaline and adrenaline kinetics in humans.
Clinical science (London, England : 1979) 1996;90(5):337-43.
1996: Gerard A Rongen; Jacques W M Lenders; J Lambrou; J J Willemsen; H Van Belle; Theo Thien; Paul Smits
Presynaptic inhibition of norepinephrine release from sympathetic nerve endings by endogenous adenosine.
Hypertension 1996;27(4):933-8.
1996: G A Rongen; E Ginneken; Theo Thien; J A Lutterman; Paul Smits
Preserved vasodilator response to adenosine in insulin-dependent diabetes mellitus.
European journal of clinical investigation 1996;26(3):192-8.
1996: A J Branten; Paul Smits; Tim Jansen; Hub Wollersheim; Theo Thien
Effect of atrial natriuretic factor on skin microcirculation versus skeletal muscle blood flow.
Journal of cardiovascular pharmacology 1996;27(2):303-6.
1996: Cees J Tack; Paul Smits; J J Willemsen; Jacques W M Lenders; Theo Thien; J A Lutterman
Effects of insulin on vascular tone and sympathetic nervous system in NIDDM.
Diabetes 1996;45(1):15-22.
1995: Peter Pickkers; Frans G M Russel; Alun HUGHES; Theo Thien; Paul Smits
Hydrochlorothiazide exerts no direct vasoactivity in the human forearm.
Journal of hypertension 1995;13(12 Pt 2):1833-6.
1995: M C Jacobs; David S Goldstein; J J Willemsen; Paul Smits; Theo Thien; Ray Dionne; Jacques W M Lenders
Neurohumoral antecedents of vasodepressor reactions.
European journal of clinical investigation 1995;25(10):754-61.
1995: Gerard A Rongen; J W Lenders; Paul Smits; Theo Thien
Clinical pharmacokinetics and efficacy of renin inhibitors.
Clinical pharmacokinetics 1995;29(1):6-14.
1995: Mirian C H Janssen; Paul Smits; J Reyenga; Theo Thien
Acute effects of flosequinan (BTS 49465) in untreated moderate to severe hypertension.
Journal of human hypertension 1995;9(5):363-8.
1995: Gerard A Rongen; Paul Smits; G Bootsma; K Ver Donck; A de Vries; Theo Thien
High-grade nucleoside transport inhibition stimulates ventilation in humans.
Journal of clinical pharmacology 1995;35(4):357-61.
1995: P J Bijlstra; Paul Smits; J A Lutterman; Theo Thien
Effect of long-term angiotensin-converting enzyme inhibition on endothelial function in patients with the insulin-resistance syndrome.
Journal of cardiovascular pharmacology 1995;25(4):658-64.
1995: Gerard A Rongen; Paul Smits; K Ver Donck; J J Willemsen; R A De Abreu; H Van Belle; Theo Thien
Hemodynamic and neurohumoral effects of various grades of selective adenosine transport inhibition in humans. Implications for its future role in cardioprotection.
The Journal of clinical investigation 1995;95(2):658-68.
1995: Paul Smits; Theo Thien
Cardiovascular effects of sulphonylurea derivatives. Implications for the treatment of NIDDM?
Diabetologia 1995;38(1):116-21.
1994: Gerard A Rongen; Paul Smits; Theo Thien
Characterization of ATP-induced vasodilation in the human forearm vascular bed.
Circulation 1994;90(4):1891-8.
1994: J Kamphuis; Paul Smits; Theo Thien
Vascular effects of pentoxifylline in humans.
Journal of cardiovascular pharmacology 1994;24(4):648-54.
1994: J J van Meyel; Paul Smits; T Dormans; P G Gerlag; Frans G M Russel; F W Gribnau
Continuous infusion of furosemide in the treatment of patients with congestive heart failure and diuretic resistance.
Journal of internal medicine 1994;235(4):329-34.
1994: Tim Jansen; Paul Smits; Jacques W M Lenders; M C Jacobs; J Willemsen; Theo Thien
Atrial natriuretic factor potentiates the human forearm vasoconstrictor response to sympathetic stimulation.
Clinical science (London, England : 1979) 1994;86(3):275-83.
1994: Cees J Tack; PM Netten; M H Scheepers; J W Meijer; Paul Smits; J Lutterman
Comparison of clinical examination, current and vibratory perception threshold in diabetic polyneuropathy.
The Netherlands journal of medicine 1994;44(2):41-9.
1994: Gerard A Rongen; Paul Smits; Theo Thien
Endothelium and the regulation of vascular tone with emphasis on the role of nitric oxide. Physiology, pathophysiology and clinical implications.
The Netherlands journal of medicine 1994;44(1):26-35.
1994: J A Timmermans; Theo Thien; Paul Smits; C H Van Os
Quantification of Ca(2+)-ATPase in erythrocytes from subjects with essential hypertension or Raynaud's phenomenon.
American journal of hypertension 1994;7(1):90-5.
1993: Gerard A Rongen; Paul Smits; Theo Thien
NG-monomethyl-L-ARG reduces the forearm vasodilator response to acetylcholine but not to methacholine in humans.
Journal of cardiovascular pharmacology 1993;22(6):884-8.
1993: Paul Smits; Elisabeth Temme; Theo Thien
The cardiovascular interaction between caffeine and nicotine in humans.
Clinical pharmacology and therapeutics 1993;54(2):194-204.
1993: M C Jacobs; Jacques W M Lenders; J A Kapma; Paul Smits; Theo Thien
Effect of chronic smoking on endothelium-dependent vascular relaxation in humans.
Clinical science (London, England : 1979) 1993;85(1):51-5.
1993: Paul Smits; J A Kapma; M C Jacobs; J Lutterman; Theo Thien
Endothelium-dependent vascular relaxation in patients with type I diabetes.
Diabetes 1993;42(1):148-53.
1992: Cees J Tack; Paul Smits; J A Lutterman
[Role of insulin resistance in diabetes mellitus and other risk factors for cardiovascular diseases].
Nederlands tijdschrift voor geneeskunde 1992;136(35):1697-701.
1992: M van Dusseldorp; Paul Smits; Jacques W M Lenders; Elisabeth Temme; Theo Thien; M B Katan
Effects of coffee on cardiovascular responses to stress: a 14-week controlled trial.
Psychosomatic medicine 1992;54(3):344-53.
1992: J J Van Meyel; P G Gerlag; Paul Smits; Frans G M Russel; Y Tan; C A Van Ginneken; F W Gribnau
Absorption of high dose furosemide (frusemide) in congestive heart failure.
Clinical pharmacokinetics 1992;22(4):308-18.
1992: J J van Meyel; Paul Smits; Frans G M Russel; P G Gerlag; Y Tan; F W Gribnau
Diuretic efficiency of furosemide during continuous administration versus bolus injection in healthy volunteers.
Clinical pharmacology and therapeutics 1992;51(4):440-4.
1991: M Y Wong Chung; Paul Smits; Jacques W M Lenders; Theo Thien
Reproducibility of the blood pressure fall at night in healthy normotensive volunteers.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1991;9(6):S324-5.
1991: Paul Smits; Peter W de Leeuw; P N van Es; Cornelis T Postma; Theo Thien
Adenosine induces renal vasodilation in primary hypertensive patients.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1991;9(6):S214-5.
1991: Cornelis T Postma; Paul Smits; G Rosenbusch; Theo Thien
The effect of caffeine on renal vein renin concentration in patients with renal arterial disease.
American journal of hypertension 1991;4(12 Pt 1):951-4.
1991: M van Dusseldorp; Paul Smits; Jacques W M Lenders; Theo Thien; M B Katan
Boiled coffee and blood pressure. A 14-week controlled trial.
Hypertension 1991;18(5):607-13.
1991: Paul Smits; C Straatman; E Pijpers; Theo Thien
Dose-dependent inhibition of the hemodynamic response to dipyridamole by caffeine.
Clinical pharmacology and therapeutics 1991;50(5 Pt 1):529-37.
1991: Tim Jansen; Paul Smits; A C Tan; Theo Thien
Attenuated forearm vasodilator response to atrial natriuretic factor in the elderly.
Hypertension 1991;18(5):640-7.
1991: Paul Smits; J W Lenders; J J Willemsen; Theo Thien
Adenosine attenuates the response to sympathetic stimuli in humans.
Hypertension 1991;18(2):216-23.
1991: Paul Smits; Frans H M Corstens; Wim R M Aengevaeren; F J Wackers; Theo Thien
False-negative dipyridamole-thallium-201 myocardial imaging after caffeine infusion.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1991;32(8):1538-41.
1991: Paul Smits; Jacques W M Lenders; J J Willemsen; J A den Arend; Theo Thien
Adenosine attenuates the vasoconstrictor response to the cold pressor test in humans.
Journal of cardiovascular pharmacology 1991;17(6):1019-22.
1991: Jacques W M Lenders; G J Janssen; Paul Smits; Theo Thien
Role of the wrist cuff in forearm plethysmography.
Clinical science (London, England : 1979) 1991;80(5):413-7.
1990: J J van Meyel; Paul Smits; F W Gribnau
Absence of magnesium sparing effect of a single dose of triamterene in combination with frusemide in healthy male adults.
British journal of clinical pharmacology 1990;30(5):774-7.
1990: Paul Smits; Jacques W M Lenders; Theo Thien
Caffeine and theophylline attenuate adenosine-induced vasodilation in humans.
Clinical pharmacology and therapeutics 1990;48(4):410-8.
1990: Tim Jansen; A C Tan; Paul Smits; T de Boo; Th J Benraad; Theo Thien
Hemodynamic effects of atrial natriuretic factor in young and elderly subjects.
Clinical pharmacology and therapeutics 1990;48(2):179-88.
1990: J J van Meyel; Y Tan; Paul Smits; Frans G M Russel; C A van Ginneken; F W Gribnau
Comparison of the diuretic effect and absorption of a single dose of furosemide and free and the fixed combinations of furosemide and triamterene in healthy male adults.
European journal of clinical pharmacology 1990;39(6):595-7.
1989: M van Dusseldorp; Paul Smits; Theo Thien; M B Katan
Effect of decaffeinated versus regular coffee on blood pressure. A 12-week, double-blind trial.
Hypertension 1989;14(5):563-9.
1989: Paul Smits; Wim R M Aengevaeren; Frans H M Corstens; Theo Thien
Caffeine reduces dipyridamole-induced myocardial ischemia.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1989;30(10):1723-6.
1989: Paul Smits; A Eijsbouts; Theo Thien
Nicotine enhances the circulatory effects of adenosine in human beings.
Clinical pharmacology and therapeutics 1989;46(3):272-8.
1989: Paul Smits; J Schouten; Theo Thien
Cardiovascular effects of two xanthines and the relation to adenosine antagonism.
Clinical pharmacology and therapeutics 1989;45(6):593-9.
1987: Paul Smits; J Schouten; Theo Thien
Respiratory stimulant effects of adenosine in man after caffeine and enprofylline.
British journal of clinical pharmacology 1987;24(6):816-9.