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Robert Snoeck
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108
Andrei, Graciela
94
De Clercq, Erik
69
Balzarini, Jan
34
McGuigan, Christopher
20
Neyts, Johan
17
Naesens, Lieve
17
Schols, Dominique
11
Holý, Antonín
10
Carangio, Antonella
9
Herdewijn, Piet
8
Fiten, Pierre
8
Opdenakker, Ghislain
7
Simonart, Thierry
7
Brancale, Andrea
6
Bron, Dominique
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All Publications
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2009: McGuigan Christopher; Derudas Marco; Quintiliani Maurizio; Andrei Graciela; Snoeck Robert; Henson Geoffrey; Balzarini Jan
2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743.
Bioorganic & medicinal chemistry letters 2009;19(22):6264-7.
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2009: Vigne Solenne; Duraffour Sophie; Andrei Graciela; Snoeck Robert; Garin Daniel; Crance Jean-Marc
Inhibition of vaccinia virus replication by two small interfering RNAs targeting B1R and G7L genes and their synergistic combination with cidofovir.
Antimicrobial agents and chemotherapy 2009;53(6):2579-88.
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2009: McGuigan Christopher; Bidet Olivier; Derudas Marco; Andrei Graciela; Snoeck Robert; Balzarini Jan
Alkenyl substituted bicyclic nucleoside analogues retain nanomolar potency against Varicella Zoster Virus.
Bioorganic & medicinal chemistry 2009;17(8):3025-7.
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2009: Naesens Lieve; Vanderlinden Evelien; Roth Erzsébet; Jeko József; Andrei Graciela; Snoeck Robert; Pannecouque Christophe; Illyés Eszter; Batta Gyula; Herczegh Pál; Sztaricskai Ferenc
Anti-influenza virus activity and structure-activity relationship of aglycoristocetin derivatives with cyclobutenedione carrying hydrophobic chains.
Antiviral research 2009;82(1):89-94.
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2008: Gammon Don B; Snoeck Robert; Fiten Pierre; Krecmerová Marcela; Holý Antonín; De Clercq Erik; Opdenakker Ghislain; Evans David H; Andrei Graciela
Mechanism of antiviral drug resistance of vaccinia virus: identification of residues in the viral DNA polymerase conferring differential resistance to antipoxvirus drugs.
Journal of virology 2008;82(24):12520-34.
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2008: Naesens Lieve; Andrei Graciela; Votruba Ivan; Krecmerová Marcela; Holý Antonín; Neyts Johan; De Clercq Erik; Snoeck Robert
Intracellular metabolism of the new antiviral compound 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine.
Biochemical pharmacology 2008;76(8):997-1005.
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2008: McGuigan Christopher; Derudas Marco; Bugert Joachim J; Andrei Graciela; Snoeck Robert; Balzarini Jan
Successful kinase bypass with new acyclovir phosphoramidate prodrugs.
Bioorganic & medicinal chemistry letters 2008;18(15):4364-7.
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2008: Dal Pozzo Fabiana; Andrei Graciela; Daelemans Dirk; Winkler Michael; Piette Jacques; De Clercq Erik; Snoeck Robert
Fluorescence-based antiviral assay for the evaluation of compounds against vaccinia virus, varicella zoster virus and human cytomegalovirus.
Journal of virological methods 2008;151(1):66-73.
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2008: Andrei Graciela; De Clercq Eric; Snoeck Robert
Novel inhibitors of human CMV.
Current opinion in investigational drugs (London, England : 2000) 2008;9(2):132-45.
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2008: Duraffour Sophie; Vigne Solenne; Vermeire Kurt; Garcel Aude; Vanstreels Els; Daelemans Dirk; Yang Guang; Jordan Robert; Hruby Dennis E; Crance Jean-Marc; Garin Daniel; Andrei Graciela; Snoeck Robert
Specific targeting of the F13L protein by ST-246 affects orthopoxvirus production differently.
Antiviral therapy 2008;13(8):977-90.
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2008: Vigne Solenne; Germi Raphaële; Duraffour Sophie; Larrat Sylvie; Andrei Graciela; Snoeck Robert; Garin Daniel; Crance Jean-Marc
Specific inhibition of orthopoxvirus replication by a small interfering RNA targeting the D5R gene.
Antiviral therapy 2008;13(3):357-68.
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2007: McGuigan Christopher; Pathirana Ranjith N; Migliore Marco; Adak Rina; Luoni Giovanna; Jones Arwyn T; Díez-Torrubia Alberto; Camarasa Maria-Jose; Velázquez Sonsoles; Henson Geoffrey; Verbeken Erik; Sienaert Rebecca; Naesens Lieve; Snoeck Robert; Andrei Graciela; Balzarini Jan
Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus.
The Journal of antimicrobial chemotherapy 2007;60(6):1316-30.
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2007: Duraffour Sophie; Snoeck Robert; Krecmerová Marcela; van Den Oord Joost; De Vos Rita; Holy Antonín; Crance Jean-Marc; Garin Daniel; De Clercq Erik; Andrei Graciela
Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models.
Antimicrobial agents and chemotherapy 2007;51(12):4410-9.
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2007: Krecmerová Marcela; Holý Antonín; Pohl Radek; Masojídková Milena; Andrei Graciela; Naesens Lieve; Neyts Johan; Balzarini Jan; De Clercq Erik; Snoeck Robert
Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: synthesis and antiviral activity.
Journal of medicinal chemistry 2007;50(23):5765-72.
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2007: Dal Pozzo Fabiana; Andrei Graciela; Lebeau Ilya; Beadle James R; Hostetler Karl Y; De Clercq Erik; Snoeck Robert
In vitro evaluation of the anti-orf virus activity of alkoxyalkyl esters of CDV, cCDV and (S)-HPMPA.
Antiviral research 2007;75(1):52-7.
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2007: Andrei G; Fiten P; Goubau P; van Landuyt H; Gordts B; Selleslag D; De Clercq E; Opdenakker G; Snoeck R
Dual infection with polyomavirus BK and acyclovir-resistant herpes simplex virus successfully treated with cidofovir in a bone marrow transplant recipient.
Transplant infectious disease : an official journal of the Transplantation Society 2007;9(2):126-31.
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2007: Lebeau Ilya; Andrei Graciela; Krecmerová Marcela; De Clercq Erik; Holy Antonin; Snoeck Robert
Inhibitory activities of three classes of acyclic nucleoside phosphonates against murine polyomavirus and primate simian virus 40 strains.
Antimicrobial agents and chemotherapy 2007;51(6):2268-73.
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2007: Krecmerová Marcela; Holý Antonín; Pískala Alois; Masojídková Milena; Andrei Graciela; Naesens Lieve; Neyts Johan; Balzarini Jan; De Clercq Erik; Snoeck Robert
Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds.
Journal of medicinal chemistry 2007;50(5):1069-77.
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2007: Scagliarini A; McInnes C J; Gallina L; Dal Pozzo F; Scagliarini L; Snoeck R; Prosperi S; Sales J; Gilray J A; Nettleton P F
Antiviral activity of HPMPC (cidofovir) against orf virus infected lambs.
Antiviral research 2007;73(3):169-74.
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2007: Duraffour Sophie; Snoeck Robert; de Vos Rita; van Den Oord Joost J; Crance Jean-Marc; Garin Daniel; Hruby Dennis E; Jordan Robert; De Clercq Erik; Andrei Graciela
Activity of the anti-orthopoxvirus compound ST-246 against vaccinia, cowpox and camelpox viruses in cell monolayers and organotypic raft cultures.
Antiviral therapy 2007;12(8):1205-16.
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2007: Andrei Gracíela; Fiten Pierre; Froeyen Matheus; De Clercq Erik; Opdenakker Ghislain; Snoeck Robert
DNA polymerase mutations in drug-resistant herpes simplex virus mutants determine in vivo neurovirulence and drug-enzyme interactions.
Antiviral therapy 2007;12(5):719-32.
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2006: Horejsí Katerina; Andrei Graciela; De Clercq Erik; Snoeck Robert; Pohl Radek; Holý Antonín
Tricyclic etheno analogs of PMEG and PMEDAP: synthesis and biological activity.
Bioorganic & medicinal chemistry 2006;14(23):8057-65.
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2006: Andrei Graciela; Gammon Don B; Fiten Pierre; De Clercq Erik; Opdenakker Ghislain; Snoeck Robert; Evans David H
Cidofovir resistance in vaccinia virus is linked to diminished virulence in mice.
Journal of virology 2006;80(19):9391-401.
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2006: Naesens Lieve; Stephens Chad E; Andrei Graciela; Loregian Arianna; De Bolle Leen; Snoeck Robert; Sowell J Walter; De Clercq Erik
Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses.
Antiviral research 2006;72(1):60-7.
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2006: Snoeck Robert
Papillomavirus and treatment.
Antiviral research 2006;71(2-3):181-91.
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2006: Lebeau Ilya; Andrei Graciela; Dal Pozzo Fabiana; Beadle James R; Hostetler Karl Y; De Clercq Erik; van den Oord Joost; Snoeck Robert
Activities of alkoxyalkyl esters of cidofovir (CDV), cyclic CDV, and (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine against orthopoxviruses in cell monolayers and in organotypic cultures.
Antimicrobial agents and chemotherapy 2006;50(7):2525-9.
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2005: Dal Pozzo F; Andrei G; Holy A; Van Den Oord J; Scagliarini A; De Clercq E; Snoeck R
Activities of acyclic nucleoside phosphonates against Orf virus in human and ovine cell monolayers and organotypic ovine raft cultures.
Antimicrobial agents and chemotherapy 2005;49(12):4843-52.
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2005: Andrei Graciela; van den Oord Joost; Fiten Pierre; Opdenakker Ghislain; De Wolf-Peeters Chris; De Clercq Erik; Snoeck Robert
Organotypic epithelial raft cultures as a model for evaluating compounds against alphaherpesviruses.
Antimicrobial agents and chemotherapy 2005;49(11):4671-80.
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2005: Stevens Miguel; Balzarini Jan; Tabarrini Oriana; Andrei Graciela; Snoeck Robert; Cecchetti Violetta; Fravolini Arnaldo; De Clercq Erik; Pannecouque Christophe
Cell-dependent interference of a series of new 6-aminoquinolone derivatives with viral (HIV/CMV) transactivation.
The Journal of antimicrobial chemotherapy 2005;56(5):847-55.
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2005: Scagliarini A; Dal Pozzo F; Gallina L; Guercio A; De Clercq E; Snoeck R; Andrei G
Ovine skin organotypic cultures applied to the ex vivo study of orf virus infection.
Veterinary research communications 2005;29 Suppl 2():245-7.
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2005: Luoni Giovanna; McGuigan Christopher; Andrei Graciela; Snoeck Robert; De Clercq Erik; Balzarini Jan
Bicyclic nucleoside inhibitors of Varicella-Zoster virus: the effect of branching in the p-alkylphenyl side chain.
Bioorganic & medicinal chemistry letters 2005;15(16):3791-6.
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2005: Andrei Graciela; Balzarini Jan; Fiten Pierre; De Clercq Erik; Opdenakker Ghislain; Snoeck Robert
Characterization of herpes simplex virus type 1 thymidine kinase mutants selected under a single round of high-dose brivudin.
Journal of virology 2005;79(9):5863-9.
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2005: Gerona-Navarro Guillermo; Pérez de Vega M Jesús; García-López M Teresa; Andrei Graciela; Snoeck Robert; De Clercq Erik; Balzarini Jan; González-Muñiz Rosario
From 1-acyl-beta-lactam human cytomegalovirus protease inhibitors to 1-benzyloxycarbonylazetidines with improved antiviral activity. A straightforward approach to convert covalent to noncovalent inhibitors.
Journal of medicinal chemistry 2005;48(7):2612-21.
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2005: Andrei Graciela; Sienaert Rebecca; McGuigan Chris; De Clercq Erik; Balzarini Jan; Snoeck Robert
Susceptibilities of several clinical varicella-zoster virus (VZV) isolates and drug-resistant VZV strains to bicyclic furano pyrimidine nucleosides.
Antimicrobial agents and chemotherapy 2005;49(3):1081-6.
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2005: Naesens L; Lenaerts L; Andrei G; Snoeck R; Van Beers D; Holy Antonin; Balzarini Jan; De Clercq Erik
Antiadenovirus activities of several classes of nucleoside and nucleotide analogues.
Antimicrobial agents and chemotherapy 2005;49(3):1010-6.
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2005: Fanourgiakis Panagiotis; Georgala Aspasia; Vekemans Marc; Triffet Agnes; De Bruyn Jean-Marc; Duchateau Valerie; Martiat Philippe; De Clercq Erik; Snoeck Robert; Wollants Elke; Rector Annabel; Van Ranst Marc; Aoun Michael
Intravesical instillation of cidofovir in the treatment of hemorrhagic cystitis caused by adenovirus type 11 in a bone marrow transplant recipient.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005;40(1):199-201.
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2005: Kelleher M R; McGuigan C; Bidet O; Carangio A; Weldon H; Andrei G; Snoeck R; De Clercq E; Balzarini J
The journey towards elucidating the anti-HCMV activity of alkylated bicyclic furano pyrimidines.
Nucleosides, nucleotides & nucleic acids 2005;24(5-7):643-5.
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2005: De Clercq Erik; Andrei G; Balzarini J; Leyssen P; Naesens L; Neyts J; Pannecouque C; Snoeck R; Ying C; Hocková D; Holý A
Antiviral potential of a new generation of acyclic nucleoside phosphonates, the 6-[2-(phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines.
Nucleosides, nucleotides & nucleic acids 2005;24(5-7):331-41.
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2004: Luoni Giovanna M; McGuigan Christopher; Andrei Graciela; Snoeck Robert; De Clercq Erik; Balzarini Jan
Bicyclic nucleoside inhibitors of varicella-zoster virus modified on the sugar moiety: 3' and 5' derivatives.
Antiviral chemistry & chemotherapy 2004;15(6):333-41.
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2004: Bidet Olivier; McGuigan Christopher; Snoeck Robert; Andrei Graciela; De Clercq Erik; Balzarini Jan
Non-nucleoside structures retain full anti-HCMV potency of the dideoxy furanopyrimidine family.
Antiviral chemistry & chemotherapy 2004;15(6):329-32.
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2004: Balzarini J; Pannecouque C; Naesens L; Andrei G; Snoeck R; De Clercq E; Hocková D; Holý A
6-[2-phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines: a new class of acyclic pyrimidine nucleoside phosphonates with antiviral activity.
Nucleosides, nucleotides & nucleic acids 2004;23(8-9):1321-7.
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2004: Snoeck R; de Clercq E; Andrei G
[Using antiviral drugs for Orthopoxvirus infections]
Médecine et maladies infectieuses 2004;34 Suppl 1():S48-50.
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2004: Hocková Dana; Holý Antonín; Masojídková Milena; Andrei Graciela; Snoeck Robert; De Clercq Erik; Balzarini Jan
Synthesis and antiviral activity of 2,4-diamino-5-cyano-6-[2-(phosphonomethoxy)ethoxy]pyrimidine and related compounds.
Bioorganic & medicinal chemistry 2004;12(12):3197-202.
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2004: Angell Annette; McGuigan Christopher; Garcia Sevillano Luis; Snoeck Robert; Andrei Graciela; De Clercq Erik; Balzarini Jan
Bicyclic anti-VZV nucleosides: thieno analogues bearing an alkylphenyl side chain have reduced antiviral activity.
Bioorganic & medicinal chemistry letters 2004;14(10):2397-9.
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2004: Gerona-Navarro Guillermo; Pérez de Vega M Jesús; García-López M Teresa; Andrei Graciela; Snoeck Robert; Balzarini Jan; De Clercq Erik; González-Muñiz Rosario
Synthesis and anti-HCMV activity of 1-acyl-beta-lactams and 1-acylazetidines derived from phenylalanine.
Bioorganic & medicinal chemistry letters 2004;14(9):2253-6.
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2004: Andrei G; De Clercq E; Snoeck R
In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir?
Antiviral research 2004;61(3):181-7.
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2004: McGuigan Christopher; Pathirana Ranjith N; Snoeck Robert; Andrei Graciela; De Clercq Erik; Balzarini Jan
Discovery of a new family of inhibitors of human cytomegalovirus (HCMV) based upon lipophilic alkyl furano pyrimidine dideoxy nucleosides: action via a novel non-nucleosidic mechanism.
Journal of medicinal chemistry 2004;47(7):1847-51.
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2004: Sienaert R; Andrei G; Snoeck R; De Clercq E; McGuigan C; Balzarini J
Inactivity of the bicyclic pyrimidine nucleoside analogues against simian varicella virus (SVV) does not correlate with their substrate activity for SVV-encoded thymidine kinase.
Biochemical and biophysical research communications 2004;315(4):877-83.
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2004: De Bolle Leen; Andrei Graciela; Snoeck Robert; Zhang Ying; Van Lommel Alfons; Otto Michael; Bousseau Anne; Roy Christine; De Clercq Erik; Naesens Lieve
Potent, selective and cell-mediated inhibition of human herpesvirus 6 at an early stage of viral replication by the non-nucleoside compound CMV423.
Biochemical pharmacology 2004;67(2):325-36.
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2004: McGuigan Christopher; Carangio Antonella; Snoeck Robert; Andrei Graciela; De Clercq Erik; Balzarini Jan
Synthesis and antiviral evaluation of some 3'-fluoro bicyclic nucleoside analogues.
Nucleosides, nucleotides & nucleic acids 2004;23(1-2):1-5.
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2003: McGuigan Christopher; Brancale Andrea; Andrei Graciela; Snoeck Robert; De Clercq Erik; Balzarini Jan
Novel bicyclic furanopyrimidines with dual anti-VZV and -HCMV activity.
Bioorganic & medicinal chemistry letters 2003;13(24):4511-3.
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2003: Hocková Dana; Holý Antonín; Masojídková Milena; Andrei Graciela; Snoeck Robert; De Clercq Erik; Balzarini Jan
5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidines-acyclic nucleoside phosphonate analogues with antiviral activity.
Journal of medicinal chemistry 2003;46(23):5064-73.
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2003: Simonart Thierry; Boelaert Johan R; Andrei Graciela; Clercq Erik De; Snoeck Robert
Iron withdrawal strategies fail to prevent the growth of SiHa-induced tumors in mice.
Gynecologic oncology 2003;90(1):91-5.
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2003: Sienaert R; Naesens L; Brancale A; Carangio A; Andrei G; Snoeck R; Van Kuilenburg A; De Clercq E; McGuigan C; Balzarini J
Metabolic and pharmacological characteristics of the bicyclic nucleoside analogues (BCNAs) as highly selective inhibitors of varicella-zoster virus (VZV).
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):995-7.
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2003: Carangio A; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic nucleoside inhibitors of varicella-zoster virus: synthesis and biological evaluation of 2',3'-dideoxy-3'-fluoro and 2'-deoxy-xylo derivatives.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):935-7.
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2003: Luoni G; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic nucleoside inhibitors of varicella-zoster virus: 5'-chloro and 3'-chloro derivatives.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):931-3.
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2003: Bidet O; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Synthesis of unusual bicyclic nucleosides bearing an unsaturated side-chain, as potential inhibitors of varicella-zoster virus (VZV).
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):817-9.
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2003: McGuigan Christopher; Jukes Alison; Blewett Sally; Barucki Hubert; Erichsen Jonathan T; Andrei Graciella; Snoeck Robert; De Clercq Erik; Balzarini Jan
Halophenyl furanopyrimidines as potent and selective anti-VZV agents.
Antiviral chemistry & chemotherapy 2003;14(3):165-70.
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2002: Rector Annabel; Azzi Nadira; Liesnard Corinne; Zlateva Kalina; Van Beers Daniele; Snoeck Robert; Van Ranst Marc
Use of polymerase chain reaction for diagnosis of disseminated adenovirus infection.
The Pediatric infectious disease journal 2002;21(12):1176-8.
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2002: Snoeck Robert; De Clercq Eric
Role of cidofovir in the treatment of DNA virus infections, other than CMV infections, in immunocompromised patients.
Current opinion in investigational drugs (London, England : 2000) 2002;3(11):1561-6.
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2002: Snoeck R; Holý A; Dewolf-Peeters C; Van Den Oord J; De Clercq E; Andrei G
Antivaccinia activities of acyclic nucleoside phosphonate derivatives in epithelial cells and organotypic cultures.
Antimicrobial agents and chemotherapy 2002;46(11):3356-61.
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2002: Vermeire Kurt; Zhang Ying; Princen Katrien; Hatse Sigrid; Samala Meinrado F; Dey Kaka; Choi Heung-Jin; Ahn Youngmi; Sodoma Andrej; Snoeck Robert; Andrei Graciela; De Clercq Erik; Bell Thomas W; Schols Dominique
CADA inhibits human immunodeficiency virus and human herpesvirus 7 replication by down-modulation of the cellular CD4 receptor.
Virology 2002;302(2):342-53.
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2002: Carangio A; Srinivasan S; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic nucleoside inhibitors of varicella-zoster virus: effect of terminal aryl substitution in the side-chain.
Antiviral chemistry & chemotherapy 2002;13(5):263-71.
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2002: Snoeck Robert; Andrei Graciela; Bodaghi Bahram; Lagneaux Laurence; Daelemans Dirk; de Clercq Erik; Neyts Johan; Schols Dominique; Naesens Lieve; Michelson Susan; Bron Dominique; Otto Michael J; Bousseau Anne; Nemecek Conception; Roy Christine
2-Chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide (CMV423), a new lead compound for the treatment of human cytomegalovirus infections.
Antiviral research 2002;55(3):413-24.
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2002: Simonart Thierry; Boelaert Johan R; Andrei Graciela; van den Oord Joost J; Degraef Chantale; Hermans Philippe; Noel Jean-Christophe; Van Vooren Jean-Paul; Heenen Michel; De Clercq Erik; Snoeck Robert
Desferrioxamine enhances AIDS-associated Kaposi's sarcoma tumor development in a xenograft model.
International journal of cancer. Journal international du cancer 2002;100(2):140-3.
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2002: Snoeck R
[Perspectives for the treatment and prevention of herpes simplex infections]
Annales de dermatologie et de vénéréologie 2002;129(4 Pt 2):662-5.
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2002: Holý Antonín; Votruba Ivan; Masojídková Milena; Andrei Graciela; Snoeck Robert; Naesens Lieve; De Clercq Erik; Balzarini Jan
6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with antiviral activity.
Journal of medicinal chemistry 2002;45(9):1918-29.
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2002: Simonart Thierry; Boelaert Johan R; Mosselmans Roger; Andrei Graciela; Noel Jean-Christophe; De Clercq Erik; Snoeck Robert
Antiproliferative and apoptotic effects of iron chelators on human cervical carcinoma cells.
Gynecologic oncology 2002;85(1):95-102.
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2002: Snoeck Robert; De Clercq Erik
New treatments for genital herpes.
Current opinion in infectious diseases 2002;15(1):49-55.
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2001: Snoeck R; Van Laethem Y; De Clercq E; De Maubeuge J; Clumeck N
Treatment of a bowenoid papulosis of the penis with local applications of cidofovir in a patient with acquired immunodeficiency syndrome.
Archives of internal medicine 2001;161(19):2382-4.
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2001: Harris S A; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Synthesis and antiviral evaluation of phosphoramidate derivatives of (E)-5-(2-bromovinyl)-2'-deoxyuridine.
Antiviral chemistry & chemotherapy 2001;12(5):293-300.
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2001: Brancale A; McGuigan C; Algain B; Savy P; Benhida R; Fourrey J L; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic anti-VZV nucleosides: Thieno analogues retain full antiviral activity.
Bioorganic & medicinal chemistry letters 2001;11(18):2507-10.
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2001: Snoeck R; Bossens M; Parent D; Delaere B; Degreef H; Van Ranst M; Noël J C; Wulfsohn M S; Rooney J F; Jaffe H S; De Clercq E
Phase II double-blind, placebo-controlled study of the safety and efficacy of cidofovir topical gel for the treatment of patients with human papillomavirus infection.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2001;33(5):597-602.
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2001: Geerinck K; Lukito G; Snoeck R; De Vos R; De Clercq E; Vanrenterghem Y; Degreef H; Maes B
A case of human orf in an immunocompromised patient treated successfully with cidofovir cream.
Journal of medical virology 2001;64(4):543-9.
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2001: Andrei G; Fiten P; De Clercq E; Snoeck R; Opdenakker G
Evaluating phenotype and genotype of drug-resistant strains in herpesviruses.
Molecular biotechnology 2001;18(2):155-67.
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2001: Carangio A; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic nucleoside inhibitors of varicella-zoster virus (VZV): Pd-catalysed synthesis of 5-aryl derivatives and their biological evaluation.
Antiviral chemistry & chemotherapy 2001;12(3):187-97.
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2001: Stephens C E; Felder T M; Sowell J W; Andrei G; Balzarini J; Snoeck R; De Clercq E
Synthesis and antiviral/antitumor evaluation of 2-amino- and 2-carboxamido-3-arylsulfonylthiophenes and related compounds as a new class of diarylsulfones.
Bioorganic & medicinal chemistry 2001;9(5):1123-32.
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2001: Srinivasan S; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic nucleoside inhibitors of varicella-zoster virus (VZV): effect of terminal unsaturation in the side-chain.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):763-6.
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2001: Wang J; Froeyen M; Hendrix C; Andrei C; Snoeck R; Lescrinier E; De Clercq E; Herdewijn P
(D)- and (L)-cyclohexenyl-G, a new class of antiviral agents: synthesis, conformational analysis, molecular modeling, and biological activity.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):727-30.
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2001: Carangio A; McGuigan C; Cahard D; Andrei G; Snoeck R; De Clercq E; Balzarini J
Synthesis and in vitro evaluation of novel anti-varicella-zoster virus (VZV) nucleosides.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):653-6.
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2001: McGuigan C; Barucki H; Carangio A; Blewett S; Srinivasan S; Andrei G; Snoeck R; De Clercq E; Balzarini J
Novel aryl substituted bicyclic furo nucleosides as extremely potent and selective anti-VZV agents.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):287-96.
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2001: De Clercq E; Andrei G; Snoeck R; De Bolle L; Naesens L; Degrève B; Balzarini J; Zhang Y; Schols D; Leyssen P; Ying C; Neyts J
Acyclic/carbocyclic guanosine analogues as anti-herpesvirus agents.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):271-85.
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2001: Blewett S; McGuigan C; Barucki H; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic furo pyrimidine nucleosides with aryloxyphenyl and halophenyl substituted side chains as potent and selective varicella-zoster virus inhibitors.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):1063-6.
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2001: McGuigan C; Brancale A; Barucki H; Srinivasan S; Jones G; Pathirana R; Carangio A; Blewett S; Luoni G; Bidet O; Jukes A; Jarvis C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Furano pyrimidines as novel potent and selective anti-VZV agents.
Antiviral chemistry & chemotherapy 2001;12(2):77-89.
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2001: Srinivasan S; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic nucleoside inhibitors of Varicella-Zoster Virus (VZV): the effect of terminal unsaturation in the side chain.
Bioorganic & medicinal chemistry letters 2001;11(3):391-3.
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2001: Snoeck R; Andrei G; De Clercq E
Cidofovir in the treatment of HPV-associated lesions.
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 2001;63(2):93-120, discussion 120-2.
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2000: McGuigan C; Barucki H; Carangio A; Blewett S; Andrei G; Snoeck R; De Clercq E; Balzarini J; Erichsen J T
Highly potent and selective inhibition of varicella-zoster virus by bicyclic furopyrimidine nucleosides bearing an aryl side chain.
Journal of medicinal chemistry 2000;43(26):4993-7.
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2000: Brancale A; Srinivasan S; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Synthesis and anti-varicella-zoster virus activity of some novel bicyclic nucleoside inhibitors: effect of enhanced aqueous solubility.
Antiviral chemistry & chemotherapy 2000;11(6):383-93.
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2000: Simonart T; Degraef C; Andrei G; Mosselmans R; Hermans P; Van Vooren J P; Noel J C; Boelaert J R; Snoeck R; Heenen M
Iron chelators inhibit the growth and induce the apoptosis of Kaposi's sarcoma cells and of their putative endothelial precursors.
The Journal of investigative dermatology 2000;115(5):893-900.
-
2000: Snoeck R
Antiviral therapy of herpes simplex.
International journal of antimicrobial agents 2000;16(2):157-9.
-
2000: McGuigan C; Pathirana R N; Jones G; Andrei G; Snoeck R; De Clercq E; Balzarini J
Anti-varicella-zoster virus bicyclic nucleosides: replacement of furo by pyrro base reduces antiviral potency.
Antiviral chemistry & chemotherapy 2000;11(5):343-8.
-
2000: Snoeck R; Andrei G; De Clercq E
Novel agents for the therapy of varicella-zoster virus infections.
Expert opinion on investigational drugs 2000;9(8):1743-51.
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2000: Brancale A; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic nucleoside inhibitors of Varicella-Zoster Virus (VZV): the effect of a terminal halogen substitution in the side-chain.
Bioorganic & medicinal chemistry letters 2000;10(11):1215-7.
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2000: Andrei G; Snoeck R; Neyts J; Sandvold M L; Myhren F; De Clercq E
Antiviral activity of ganciclovir elaidic acid ester against herpesviruses.
Antiviral research 2000;45(3):157-67.
-
2000: Andrei G; Snoeck R; De Clercq E; Esnouf R; Fiten P; Opdenakker G
Resistance of herpes simplex virus type 1 against different phosphonylmethoxyalkyl derivatives of purines and pyrimidines due to specific mutations in the viral DNA polymerase gene.
The Journal of general virology 2000;81(Pt 3):639-48.
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2000: Wang J; Froeyen M; Hendrix C; Andrei G; Snoeck R; De Clercq E; Herdewijn P
The cyclohexene ring system as a furanose mimic: synthesis and antiviral activity of both enantiomers of cyclohexenylguanine.
Journal of medicinal chemistry 2000;43(4):736-45.
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2000: Andrei G; Snoeck R; Schols D; De Clercq E
Induction of apoptosis by cidofovir in human papillomavirus (HPV)-positive cells.
Oncology research 2000;12(9-10):397-408.
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1999: McGuigan C; Yarnold C J; Jones G; Velázquez S; Barucki H; Brancale A; Andrei G; Snoeck R; De Clercq E; Balzarini J
Potent and selective inhibition of varicella-zoster virus (VZV) by nucleoside analogues with an unusual bicyclic base.
Journal of medicinal chemistry 1999;42(22):4479-84.
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1999: Holý A; Günter J; Dvoráková H; Masojídková M; Andrei G; Snoeck R; Balzarini J; De Clercq E
Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base.
Journal of medicinal chemistry 1999;42(12):2064-86.
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1999: Simonart T; Andrei G; Parent D; Van Vooren J P; De Clercq E; Snoeck R
In vitro sensitivity of Kaposi's sarcoma cells to various chemotherapeutic agents including acyclic nucleoside phosphonates.
Antiviral chemistry & chemotherapy 1999;10(3):129-34.
-
1999: De Clercq E; Andrei G; Balzarini J; Hatse S; Liekens S; Naesens L; Neyts J; Snoeck R
Antitumor potential of acyclic nucleoside phosphonates.
Nucleosides & nucleotides 1999;18(4-5):759-71.
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1999: Martinez A; Esteban A I; Castro A; Gil C; Conde S; Andrei G; Snoeck R; Balzarini J; De Clercq E
Novel potential agents for human cytomegalovirus infection: synthesis and antiviral activity evaluation of benzothiadiazine dioxide acyclonucleosides.
Journal of medicinal chemistry 1999;42(7):1145-50.
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1999: Snoeck R; Andrei G; De Clercq E
Current pharmacological approaches to the therapy of varicella zoster virus infections: a guide to treatment.
Drugs 1999;57(2):187-206.
-
1998: Snoeck R; Andrei G; De Clercq E
Specific therapies for human papilloma virus infections.
Current opinion in infectious diseases 1998;11(6):733-7.
-
1998: Simonart T; Noel J C; Andrei G; Parent D; Van Vooren J P; Hermans P; Lunardi-Yskandar Y; Lambert C; Dieye T; Farber C M; Liesnard C; Snoeck R; Heenen M; Boelaert J R
Iron as a potential co-factor in the pathogenesis of Kaposi's sarcoma?
International journal of cancer. Journal international du cancer 1998;78(6):720-6.
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1998: Witvrouw M; Daelemans D; Pannecouque C; Neyts J; Andrei G; Snoeck R; Vandamme A M; Balzarini J; Desmyter J; Baba M; De Clercq E
Broad-spectrum antiviral activity and mechanism of antiviral action of the fluoroquinolone derivative K-12.
Antiviral chemistry & chemotherapy 1998;9(5):403-11.
-
1998: Simonart T; Noel J C; De Dobbeleer G; Parent D; Van Vooren J P; De Clercq E; Snoeck R
Treatment of classical Kaposi's sarcoma with intralesional injections of cidofovir: report of a case.
Journal of medical virology 1998;55(3):215-8.
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1998: Snoeck R; Wellens W; Desloovere C; Van Ranst M; Naesens L; De Clercq E; Feenstra L
Treatment of severe laryngeal papillomatosis with intralesional injections of cidofovir [(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine].
Journal of medical virology 1998;54(3):219-25.
-
1998: Neyts J; Balzarini J; Andrei G; Chaoyong Z; Snoeck R; Zimmermann A; Mertens T; Karlsson A; De Clercq E
Intracellular metabolism of the N7-substituted acyclic nucleoside analog 2-amino-7-(1,3-dihydroxy-2-propoxymethyl)purine, a potent inhibitor of herpesvirus replication.
Molecular pharmacology 1998;53(1):157-65.
-
1998: Andrei G; Snoeck R; Piette J; Delvenne P; De Clercq E
Inhibiting effects of cidofovir (HPMPC) on the growth of the human cervical carcinoma (SiHa) xenografts in athymic nude mice.
Oncology research 1998;10(10):533-9.
-
1998: Andrei G; Snoeck R; Piette J; Delvenne P; De Clercq E
Antiproliferative effects of acyclic nucleoside phosphonates on human papillomavirus (HPV)-harboring cell lines compared with HPV-negative cell lines.
Oncology research 1998;10(10):523-31.
-
1997: Andrei G; Snoeck R; Vandeputte M; De Clercq E
Activities of various compounds against murine and primate polyomaviruses.
Antimicrobial agents and chemotherapy 1997;41(3):587-93.
-
1996: Lagneaux L; Delforge A; Snoeck R; Bosmans E; Schols D; De Clereq E; Stryckmans P; Bron D
Imbalance in production of cytokines by bone marrow stromal cells following cytomegalovirus infection.
The Journal of infectious diseases 1996;174(5):913-9.
-
1996: Snoeck R; Andrei G; De Clercq E
Patterns of resistance and sensitivity to antiviral compounds of drug-resistant strains of human cytomegalovirus selected in vitro.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1996;15(7):574-9.
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1996: Leydet A; El Hachemi H; Boyer B; Lamaty G; Roque J P; Schols D; Snoeck R; Andrei G; Ikeda S; Neyts J; Reymen D; Este J; Witvrouw M; De Clercq E
Polyanion inhibitors of human immunodeficiency virus and other viruses. Part 2. Polymerized anionic surfactants derived from amino acids and dipeptides.
Journal of medicinal chemistry 1996;39(8):1626-34.
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1996: Lagneaux L; Delforge A; Snoeck R; Bosmans E; Moreau J F; Taupin J L; De Clercq E; Stryckmans P; Bron D
Human cytomegalovirus increases constitutive production of interleukin-6 and leukemia inhibitory factor by bone marrow stromal cells.
Blood 1996;87(1):59-66.
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1995: Andrei G; Snoeck R; De Clercq E
Susceptibilities of several drug-resistant herpes simplex virus type 1 strains to alternative antiviral compounds.
Antimicrobial agents and chemotherapy 1995;39(7):1632-5.
-
1995: Leydet A; Barthelemy P; Boyer B; Lamaty G; Roque J P; Bousseau A; Evers M; Hénin Y; Snoeck R; Andrei G
Polyanion inhibitors of human immunodeficiency virus and other viruses. 1. Polymerized anionic surfactants.
Journal of medicinal chemistry 1995;38(13):2433-40.
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1995: Andrei G; Snoeck R; Reymen D; Liesnard C; Goubau P; Desmyter J; De Clercq E
Comparative activity of selected antiviral compounds against clinical isolates of varicella-zoster virus.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1995;14(4):318-29.
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1995: Verheggen I; Van Aerschot A; Van Meervelt L; Rozenski J; Wiebe L; Snoeck R; Andrei G; Balzarini J; Claes P; De Clercq E
Synthesis, biological evaluation, and structure analysis of a series of new 1,5-anhydrohexitol nucleosides.
Journal of medicinal chemistry 1995;38(5):826-35.
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1995: Van Cutsem E; Snoeck R; Van Ranst M; Fiten P; Opdenakker G; Geboes K; Janssens J; Rutgeerts P; Vantrappen G; de Clercq E
Successful treatment of a squamous papilloma of the hypopharynx-esophagus by local injections of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine.
Journal of medical virology 1995;45(2):230-5.
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1995: Neyts J; Jähne G; Andrei G; Snoeck R; Winkler I; De Clercq E
In vivo antiherpesvirus activity of N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine.
Antimicrobial agents and chemotherapy 1995;39(1):56-60.
-
1994: Neyts J; Andrei G; Snoeck R; Jähne G; Winkler I; Helsberg M; Balzarini J; De Clercq E
The N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine is a potent and selective inhibitor of herpesvirus replication.
Antimicrobial agents and chemotherapy 1994;38(12):2710-6.
-
1994: Snoeck R; Gérard M; Sadzot-Delvaux C; Andrei G; Balzarini J; Reymen D; Ahadi N; De Bruyn J M; Piette J; Rentier B
Meningoradiculoneuritis due to acyclovir-resistant varicella zoster virus in an acquired immune deficiency syndrome patient.
Journal of medical virology 1994;42(4):338-47.
-
1994: Snoeck R; Andrei G; Gérard M; Silverman A; Hedderman A; Balzarini J; Sadzot-Delvaux C; Tricot G; Clumeck N; De Clercq E
Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC).
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1994;18(4):570-8.
-
1994: Lagneaux L; Delforge A; Snoeck R; Stryckmans P; Bron D
Decreased production of cytokines after cytomegalovirus infection of marrow-derived stromal cells.
Experimental hematology 1994;22(1):26-30.
-
1993: Snoeck R; Gérard M; Sadzot-Delvaux C; Andrei G; Balzarini J; Reymen D; Piette J; Rentier B; Clumeck N; De Clercq E
Meningoradiculoneuritis due to acyclovir-resistant varicella-zoster virus in a patient with AIDS.
The Journal of infectious diseases 1993;168(5):1330-1.
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1993: Snoeck R; Andrei G; De Clercq E; Gerard M; Clumeck N; Tricot G; Sadzot-Delvaux C
A new topical treatment for resistant herpes simplex infections.
The New England journal of medicine 1993;329(13):968-9.
-
1993: Verheggen I; Van Aerschot A; Toppet S; Snoeck R; Janssen G; Balzarini J; De Clercq E; Herdewijn P
Synthesis and antiherpes virus activity of 1,5-anhydrohexitol nucleosides.
Journal of medicinal chemistry 1993;36(14):2033-40.
-
1993: Snoeck R; Andrei G; Neyts J; Schols D; Cools M; Balzarini J; De Clercq E
Inhibitory activity of S-adenosylhomocysteine hydrolase inhibitors against human cytomegalovirus replication.
Antiviral research 1993;21(3):197-216.
-
1993: Wigerinck P; Kerremans L; Claes P; Snoeck R; Maudgal P; De Clercq E; Herdewijn P
Synthesis and antiviral activity of 5-thien-2-yl-2'-deoxyuridine analogues.
Journal of medicinal chemistry 1993;36(5):538-43.
-
1993: de Clercq E; Snoeck R
[Highly specific inhibitors of human immunodeficiency virus type I that are particularly targeted at the reverse transcriptase]
Pathologie-biologie 1993;41(3):230-6.
-
1993: Balzarini J; Holy A; Jindrich J; Naesens L; Snoeck R; Schols D; De Clercq E
Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine.
Antimicrobial agents and chemotherapy 1993;37(2):332-8.
-
1992: Snoeck R; Andrei G; Schols D; Balzarini J; De Clercq E
Activity of different antiviral drug combinations against human cytomegalovirus replication in vitro.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1992;11(12):1144-55.
-
1992: Yamamoto N; Schols D; De Clercq E; Debyser Z; Pauwels R; Balzarini J; Nakashima H; Baba M; Hosoya M; Snoeck R
Mechanism of anti-human immunodeficiency virus action of polyoxometalates, a class of broad-spectrum antiviral agents.
Molecular pharmacology 1992;42(6):1109-17.
-
1992: Snoeck R; Schols D; Sadzot-Delvaux C; Cloes J M; Andrei G; De Clercq E; Piette J; Rentier B
Flow cytometric method for the detection of gpI antigens of varicella zoster virus and evaluation of anti-VZV agents.
Journal of virological methods 1992;38(2):243-54.
-
1992: De Clercq E; Snoeck R
[Current acquisitions in antiviral drugs (anti-HIV)]
Journal de pharmacie de Belgique 1992;47(4):317-22.
-
1992: Neyts J; Snoeck R; Schols D; Balzarini J; Esko J D; Van Schepdael A; De Clercq E
Sulfated polymers inhibit the interaction of human cytomegalovirus with cell surface heparan sulfate.
Virology 1992;189(1):48-58.
-
1992: Vandendriessche F; Snoeck R; Janssen G; Hoogmartens J; Van Aerschot A; De Clercq E; Herdewijn P
Synthesis and antiviral activity of acyclic nucleosides with a 3(S),5-dihydroxypentyl or 4(R)-methoxy-3(S),5-dihydroxypentyl side chain.
Journal of medicinal chemistry 1992;35(8):1458-65.
-
1992: Andrei G; Snoeck R; Goubau P; Desmyter J; De Clercq E
Comparative activity of various compounds against clinical strains of herpes simplex virus.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1992;11(2):143-51.
-
1991: Andrei G; Snoeck R; Schols D; Goubau P; Desmyter J; De Clercq E
Comparative activity of selected antiviral compounds against clinical isolates of human cytomegalovirus.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1991;10(12):1026-33.
-
1991: Neyts J; Snoeck R; Schols D; Himpens B; De Clercq E
Sensitive, reproducible and convenient fluorometric assay for the in vitro evaluation of anti-cytomegalovirus agents.
Journal of virological methods 1991;35(1):27-38.
-
1991: Wigerinck P; Pannecouque C; Snoeck R; Claes P; De Clercq E; Herdewijn P
5-(5-Bromothien-2-yl)-2'-deoxyuridine and 5-(5-chlorothien-2-yl)-2'-deoxyuridine are equipotent to (E)-5-(2-bromovinyl)-2'-deoxyuridine in the inhibition of herpes simplex virus type I replication.
Journal of medicinal chemistry 1991;34(8):2383-9.
-
1991: Neyts J; Snoeck R; Balzarini J; De Clercq E
Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro.
Antiviral research 1991;16(1):41-52.
-
1991: Snoeck R; Schols D; Andrei G; Neyts J; De Clercq E
Antiviral activity of anti-cytomegalovirus agents (HPMPC, HPMPA) assessed by a flow cytometric method and DNA hybridization technique.
Antiviral research 1991;16(1):1-9.
-
1991: Wigerinck P; Snoeck R; Claes P; De Clercq E; Herdewijn P
Synthesis and antiviral activity of 5-heteroaryl-substituted 2'-deoxyuridines.
Journal of medicinal chemistry 1991;34(6):1767-72.
-
1991: Balzarini J; Holy A; Jindrich J; Dvorakova H; Hao Z; Snoeck R; Herdewijn P; Johns D G; De Clercq E
9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(11):4961-5.
-
1991: De Clercq E; Cools M; Balzarini J; Snoeck R; Andrei G; Hosoya M; Shigeta S; Ueda T; Minakawa N; Matsuda A
Antiviral activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4- carboxamide and related compounds.
Antimicrobial agents and chemotherapy 1991;35(4):679-84.
-
1991: Bron D; Lagneaux L; Delforge A; Otte C; Snoeck R; Stryckmans P
Prevention of CMV-induced myelosuppression by anti-CMV antibodies: an in vitro model.
Experimental hematology 1991;19(2):132-5.
-
1990: Neyts J; Snoeck R; Schols D; Balzarini J; De Clercq E
Selective inhibition of human cytomegalovirus DNA synthesis by (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine [(S)-HPMPC] and 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG).
Virology 1990;179(1):41-50.
-
1990: Snoeck R; Lagneaux L; Delforge A; Bron D; Van der Auwera P; Stryckmans P; Balzarini J; De Clercq E
Inhibitory effects of potent inhibitors of human immunodeficiency virus and cytomegalovirus on the growth of human granulocyte-macrophage progenitor cells in vitro.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1990;9(8):615-9.
-
1990: Baba M; De Clercq E; Schols D; Pauwels R; Snoeck R; Van Boeckel C; Van Dedem G; Kraaijeveld N; Hobbelen P; Ottenheijm H
Novel sulfated polysaccharides: dissociation of anti-human immunodeficiency virus activity from antithrombin activity.
The Journal of infectious diseases 1990;161(2):208-13.
-
1989: Schols D; Snoeck R; Neyts J; de Clercq E
Detection of immediate early, early and late antigens of human cytomegalovirus by flow cytometry.
Journal of virological methods 1989;26(3):247-54.
-
1988: Snoeck R; Sakuma T; De Clercq E; Rosenberg I; Holy A
(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, a potent and selective inhibitor of human cytomegalovirus replication.
Antimicrobial agents and chemotherapy 1988;32(12):1839-44.
-
1988: Baba M; Snoeck R; Pauwels R; de Clercq E
Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virus.
Antimicrobial agents and chemotherapy 1988;32(11):1742-5.
-
1988: Pauwels R; Balzarini J; Baba M; Snoeck R; Schols D; Herdewijn P; Desmyter J; De Clercq E
Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds.
Journal of virological methods 1988;20(4):309-21.
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