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Evan Snyder

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Kumiko Ijichi; Jean-Pyo Lee; Craig S Moore; Robb R Pagarigan; Evan Y Snyder; Paige N Winokur; Ernesto R Bongarzone; Graham D Brown; Stephen J Crocker
MMP-3 mediates psychosine-induced globoid cell formation: implications for leukodystrophy pathology.
Rodolfo Gonzalez; Louise C Laurent; Alexander Noskov; Alina Ostrowska; Tatiana Abramihina; Francesca S Boscolo; Mathew Brock; John S Craw; Ibon Garitaonandia; Evan Y Snyder; Gerald K Wambua; Ruslan A Semechkin
Deriving dopaminergic neurons for clinical use. A practical approach.
Paola Bignone; Walter D Funk; Rachel A Krupa; Evan Y Snyder; Hal Sternberg; Michael D West; David Larocca
Identification of human embryonic progenitor cell targeting peptides using phage display.

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2013: Kumiko Ijichi; Jean-Pyo Lee; Craig S Moore; Robb R Pagarigan; Evan Y Snyder; Paige N Winokur; Ernesto R Bongarzone; Graham D Brown; Stephen J Crocker
MMP-3 mediates psychosine-induced globoid cell formation: implications for leukodystrophy pathology.
Glia 2013;61(5):765-77.
2013: Rodolfo Gonzalez; Louise C Laurent; Alexander Noskov; Alina Ostrowska; Tatiana Abramihina; Francesca S Boscolo; Mathew Brock; John S Craw; Ibon Garitaonandia; Evan Y Snyder; Gerald K Wambua; Ruslan A Semechkin
Deriving dopaminergic neurons for clinical use. A practical approach.
Scientific reports 2013;3():1463.
2013: Paola Bignone; Walter D Funk; Rachel A Krupa; Evan Y Snyder; Hal Sternberg; Michael D West; David Larocca
Identification of human embryonic progenitor cell targeting peptides using phage display.
PloS one 2013;8(3):e58200.
2012: Yang D Teng; Dou Yu; Susanna C Benn; Robert H Brown; Bin Cheng; Kadir Erkmen; Inbo Han; Steven N Kalkanis; Mahesh B Lachyankar; Jianxue Li; Jeronia Lládo; Nicholas J Maragakis; Michael Marconi; Renna C Onario; Serge Przedborski; D Eugene Redmond; Jeffrey rothstein; Jeremy M Shefner; Richard L Sidman; Evan Y Snyder
Multimodal actions of neural stem cells in a mouse model of ALS: a meta-analysis.
Science translational medicine 2012;4(165):165ra164.
2012: Nirmalya Ghosh; Andre Obenaus; Evan Y Snyder; Beatriz Tone; Christine I Turenius; Xiangpeng Yuan; Kamalakar Ambadipudi; Stephen Ashwal
Automated core-penumbra quantification in neonatal ischemic brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2012;32(12):2161-70.
2012: Isabel G Newton; Warren C Plaisted; Alice Y Shih; Evan Y Snyder; Annelie E Abrahamsson Schairer; Catriona H M Jamieson; Steven Messina-Graham; Robert F Mattrey
Optical imaging of progenitor cell homing to patient-derived tumors.
Contrast media & molecular imaging 2012;7(6):525-36.
2012: Pranav Soman; Brian T D Tobe; Kenneth S Vecchio; Alicia A M Winquist; Jin Woo Lee; Ilyas Singec; Evan Y Snyder; Shaochen Chen
Three-dimensional scaffolding to investigate neuronal derivatives of human embryonic stem cells.
Biomedical microdevices 2012;14(5):829-38.
2012: Evan Y Snyder; Yang D Teng
Stem cells and spinal cord repair.
The New England journal of medicine 2012;366(20):1940-2.
2012: Brian T D Tobe; Andrew M Crain; Junjie Hou; Ilyas Singec; Evan Y Snyder; Laurence M Brill
Phosphoproteomic analysis: an emerging role in deciphering cellular signaling in human embryonic stem cells and their differentiated derivatives.
Stem cell reviews 2012;8(1):16-31.
2012: Angéline Serre; Evan Y Snyder; Jacques Mallet; Delphine Buchet
Overexpression of basic helix-loop-helix transcription factors enhances neuronal differentiation of fetal human neural progenitor cells in various ways.
Stem cells and development 2012;21(4):539-53.
2011: yang teng; Dustin R Wakeman; Junmei Wang; Dou Yu; Serdar Kabatas; Robert Langer; Jianxue Li; D Eugene Redmond; Alexander E Ropper; Evan Y Snyder; Maryrose P Sullivan; Richard L Sidman
Functional multipotency of stem cells: a conceptual review of neurotrophic factor-based evidence and its role in translational research.
Current neuropharmacology 2011;9(4):574-85.
2011: Brian T D Tobe; Evan Y Snyder; Jeffrey S Nye
Modeling complex neuropsychiatric disorders with human induced pluripotent stem cells.
Current opinion in pharmacology 2011;11(5):521-7.
2011: Evan Y Snyder
The intricate dance between repair and inflammation: introduction to special issue.
Experimental neurology 2011;230(1):1-2.
2011: Evan Y Snyder
The risk of putting something where it does not belong: mesenchymal stem cells produce masses in the brain.
Experimental neurology 2011;230(1):75-7.
2011: Rodolfo Gonzalez; Jae Wook Lee; Evan Y Snyder; Peter G Schultz
Dorsomorphin promotes human embryonic stem cell self-renewal.
Angewandte Chemie (International ed. in English) 2011;50(15):3439-41.
2011: Kwang S Kim; Hong J Lee; Han S Jeong; Jianxue Li; Yang D Teng; Richard L Sidman; Evan Y Snyder; Seung U Kim
Self-renewal induced efficiently, safely, and effective therapeutically with one regulatable gene in a human somatic progenitor cell.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(12):4876-81.
2011: Andre Obenaus; Nejmi Dilmac; Beatriz Tone; Hou Rou Tian; Richard Hartman; Murat Digicaylioglu; Evan Y Snyder; Stephen Ashwal
Long-term magnetic resonance imaging of stem cells in neonatal ischemic injury.
Annals of neurology 2011;69(2):282-91.
2011: Xuejun H Parsons; David B Smotrich; Evan Y Snyder; Yang D Teng; James F Parsons; Dennis A Moore
Efficient derivation of human cardiac precursors and cardiomyocytes from pluripotent human embryonic stem cells with small molecule induction.
Journal of visualized experiments : JoVE 2011;(57):e3274.
2011: Xuejun H Parsons; David B Smotrich; Evan Y Snyder; Yang D Teng; James F Parsons; Dennis A Moore
Efficient derivation of human neuronal progenitors and neurons from pluripotent human embryonic stem cells with small molecule induction.
Journal of visualized experiments : JoVE 2011;(56):e3273.
2011: Igor I. Katkov; Brandon Nelson; Evan Y Snyder; Flavio Cimadamore; Natalia G Kan; Alexey V Terskikh
DMSO-Free Programmed Cryopreservation of Fully Dissociated and Adherent Human Induced Pluripotent Stem Cells.
Stem cells international 2011;2011():981606.
2010: Jianxue Li; Xuesong Gu; Yinghua Ma; Monica L Calicchio; Dong Kong; Yang D Teng; Lili Yu; Andrew M Crain; Timothy K Vartanian; Renata Pasqualini; Wadih Arap; Towia A Libermann; Evan Y Snyder; Richard L Sidman
Nna1 mediates Purkinje cell dendritic development via lysyl oxidase propeptide and NF-κB signaling.
Neuron 2010;68(1):45-60.
2010: Andrei V Chernov; Svetlana Baranovskaya; Vladislav S Golubkov; Dustin R Wakeman; Evan Y Snyder; Roy Williams; Alex Y Strongin
Microarray-based transcriptional and epigenetic profiling of matrix metalloproteinases, collagens, and related genes in cancer.
The Journal of biological chemistry 2010;285(25):19647-59.
2010: Johan Jäderstad; Linda M Jäderstad; Jianxue Li; Satyan Chintawar; Carmen Salto; Massimo Pandolfo; Vaclav Ourednik; Yang D Teng; Richard L Sidman; Ernest Arenas; Evan Y Snyder; Eric Herlenius
Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(11):5184-9.
2010: Jeffrey N Lindquist; David A Cheresh; Evan Y Snyder
Derivation of vasculature from embryonic stem cells.
Current protocols in stem cell biology 2010;Chapter 1():Unit 1F.9.
2010: Rodolfo Gonzalez; Lori L Jennings; Mark Knuth; Anthony P Orth; Heath E Klock; Weija Ou; Julie Feuerhelm; Mitchell V Hull; Eric Koesema; Yuping Wang; Jia Zhang; Chunlei Wu; Charles Y Cho; Andrew I Su; Serge Batalov; Hong Chen; Kristen Johnson; Bryan Laffitte; Deborah G Nguyen; Evan Y Snyder; Peter G Schultz; Jennifer L Harris; Scott A Lesley
Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(8):3552-7.
2010: Maria Stella Carro; Wei Keat Lim; Mariano Alvarez; Robert J Bollo; Xudong Zhao; Evan Y Snyder; Erik P Sulman; Sandrine L Anne; Fiona Doetsch; Howard Colman; Anna Lasorella; Ken Aldape; Andrea Califano; Antonio Iavarone
The transcriptional network for mesenchymal transformation of brain tumours.
Nature 2010;463(7279):318-25.
2010: Tom N Grammatopoulos; Susan M Jones; Masami Yoshimura; Brian R Hoover; Mita Das; Evan Y Snyder; Gaynor A Larson; Nancy R Zahniser; Boris Tabakoff; W Michael Zawada
Neurotransplantation of stem cells genetically modified to express human dopamine transporter reduces alcohol consumption.
Stem cell research & therapy 2010;1(5):36.
2010: Carol Lynn Curchoe; Jochen Maurer; Sonja J McKeown; Giulio Cattarossi; Flavio Cimadamore; Mats Nilbratt; Evan Y Snyder; Marianne Bronner-Fraser; Alexey V Terskikh
Early acquisition of neural crest competence during hESCs neuralization.
PloS one 2010;5(11):e13890.
2010: Jennifer Katz; Bryan Keenan; Evan Y Snyder
Culture and manipulation of neural stem cells.
Advances in experimental medicine and biology 2010;671():13-22.
2009: Václav Ourednik; Jitka Ourednik; Yifang Xu; Ying Zhang; William P Lynch; Evan Y Snyder; Melitta Schachner
Cross-talk between stem cells and the dysfunctional brain is facilitated by manipulating the niche: evidence from an adhesion molecule.
Stem cells (Dayton, Ohio) 2009;27(11):2846-56.
2009: Rahul Jandial; Evan Y Snyder
A safer stem cell: on guard against cancer.
Nature medicine 2009;15(9):999-1001.
2009: Araceli Espinosa-Jeffrey; Dustin R Wakeman; Seung U Kim; Evan Y Snyder; Jean de Vellis
Culture system for rodent and human oligodendrocyte specification, lineage progression, and maturation.
Current protocols in stem cell biology 2009;Chapter 2():Unit 2D.4.
2009: Mylvaganam Jeyakumar; Jean-Pyo Lee; Nicola R Sibson; John P Lowe; Daniel J Stuckey; Katie Tester; Gerald Fu; Robin Newlin; David A Smith; Evan Y Snyder; Frances M Platt
Neural stem cell transplantation benefits a monogenic neurometabolic disorder during the symptomatic phase of disease.
Stem cells (Dayton, Ohio) 2009;27(9):2362-70.
2009: Laurence M Brill; Wen Xiong; KiBum Lee; Scott B Ficarro; Andrew Crain; Yue Xu; Alexey V Terskikh; Evan Y Snyder; Sheng Ding
Phosphoproteomic analysis of human embryonic stem cells.
Cell stem cell 2009;5(2):204-13.
2009: Jean-Pyo Lee; David J Tsai; Kook In Park; Alan R Harvey; Evan Y Snyder
The dynamics of long-term transgene expression in engrafted neural stem cells.
The Journal of comparative neurology 2009;515(1):83-92.
2009: Suresh N Magge; Saafan Z Malik; Nicolas C Royo; H Isaac Chen; LiYa Yu; Evan Y Snyder; Donald M O'Rourke; Deborah J Watson
Role of monocyte chemoattractant protein-1 (MCP-1/CCL2) in migration of neural progenitor cells toward glial tumors.
Journal of neuroscience research 2009;87(7):1547-55.
2009: Dustin R Wakeman; Martin R Hofmann; D Eugene Redmond; Yang D Teng; Evan Y Snyder
Long-term multilayer adherent network (MAN) expansion, maintenance, and characterization, chemical and genetic manipulation, and transplantation of human fetal forebrain neural stem cells.
Current protocols in stem cell biology 2009;Chapter 2():Unit2D.3.
2009: Stephen Ashwal; Andre Obenaus; Evan Y Snyder
Neuroimaging as a basis for rational stem cell therapy.
Pediatric neurology 2009;40(3):227-36.
2009: Lei Wang; Jishu Shi; Frederik W van Ginkel; Liqiong Lan; Glenn Niemeyer; Douglas R Martin; Evan Y Snyder; Nancy R Cox
Neural stem/progenitor cells modulate immune responses by suppressing T lymphocytes with nitric oxide and prostaglandin E2.
Experimental neurology 2009;216(1):177-83.
2009: Fernanda I Staquicini; Emmanuel Dias-Neto; Jianxue Li; Evan Y Snyder; Richard L Sidman; Renata Pasqualini; Wadih Arap
Discovery of a functional protein complex of netrin-4, laminin gamma1 chain, and integrin alpha6beta1 in mouse neural stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2903-8.
2009: Xuejun H Parsons; Yang D Teng; Evan Y Snyder
Important precautions when deriving patient-specific neural elements from pluripotent cells.
Cytotherapy 2009;11(7):815-24.
2009: Jennifer Katz; Joseph Krueger; Brunhilde Felding-Habermann; Evan Y Snyder
Maintaining and engineering neural stem cells for delivery of genetically encoded therapy to brain tumors.
Methods in molecular biology (Clifton, N.J.) 2009;568():249-59.
2009: Craig M Neville; Albert Y Huang; Jeffrey Y Shyu; Evan Y Snyder; Tessa A Hadlock; Cathryn A Sundback
Neural precursor cell lines promote neurite branching.
The International journal of neuroscience 2009;119(1):15-39.
2008: Dario O Fauza; Russell W Jennings; yang teng; Evan Y Snyder
Neural stem cell delivery to the spinal cord in an ovine model of fetal surgery for spina bifida.
Surgery 2008;144(3):367-73.
2008: Kimberly B Bjugstad; yang teng; D Eugene Redmond; John D Elsworth; Robert H Roth; Shannon K Cornelius; Evan Y Snyder; John R Sladek
Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease.
Experimental neurology 2008;211(2):362-9.
2008: Ilyas Singec; Evan Y Snyder
Inflammation as a matchmaker: revisiting cell fusion.
Nature cell biology 2008;10(5):503-5.
2008: Rodolfo Gonzalez; Jeanne F Loring; Evan Y Snyder
Preparation of autogenic human feeder cells for growth of human embryonic stem cells.
Current protocols in stem cell biology 2008;Chapter 1():Unit 1C.5.1-1C.5.15.
2008: Rahul Jandial; Ilyas Singec; Christopher P Ames; Evan Y Snyder
Genetic modification of neural stem cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(3):450-7.
2008: Jean-Pyo Lee; Scott McKercher; Franz-Josef Muller; Evan Y Snyder
Neural stem cell transplantation in mouse brain.
Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.] 2008;Chapter 3():Unit 3.10.
2008: Rahul Jandial; Hoi Sang U; Michael L Levy; Evan Y Snyder
Brain tumor stem cells and the tumor microenvironmen.
Neurosurgical focus 2008;24(3-4):E27.
2008: Rahul Jandial; Henry E Aryan; John Park; William T Taylor; Evan Y Snyder
Stem cell-mediated regeneration of the intervertebral disc: cellular and molecular challenge.
Neurosurgical focus 2008;24(3-4):E21.
2007: Lei Wang; Douglas R Martin; Henry J Baker; Kurt R Zinn; John C Kappes; Haitao Ding; Atoska S Gentry; Scarlett Harper; Evan Y Snyder; Nancy R Cox
Neural progenitor cell transplantation and imaging in a large animal model.
Neuroscience research 2007;59(3):327-40.
2007: Ilyas Singec; Evan Y Snyder
Quo vadis brain repair? A long axonal journey in the adult CNS.
Cell stem cell 2007;1(4):355-6.
2007: Mark A Parker; Deborah A Corliss; Brianna Gray; Julia K Anderson; Richard P Bobbin; Evan Y Snyder; Douglas A Cotanche
Neural stem cells injected into the sound-damaged cochlea migrate throughout the cochlea and express markers of hair cells, supporting cells, and spiral ganglion cells.
Hearing research 2007;232(1-2):29-43.
2007: Lidia De Filippis; Giuseppe Lamorte; Evan Y Snyder; Antonio Malgaroli; Angelo L Vescovi
A novel, immortal, and multipotent human neural stem cell line generating functional neurons and oligodendrocytes.
Stem cells (Dayton, Ohio) 2007;25(9):2312-21.
2007: D Eugene Redmond; Kimberly B Bjugstad; yang teng; Václav Ourednik; Jitka Ourednik; Dustin R Wakeman; Xuejun H Parsons; Rodolfo Gonzalez; Barbara C Blanchard; Seung Kim; Zezong Gu; Stuart A Lipton; Eleni A Markakis; Robert H Roth; John D Elsworth; John R Sladek; Richard L Sidman; Evan Y Snyder
Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(29):12175-80.
2007: Richard L Sidman; Jianxue Li; Gregory R Stewart; Jennifer Clarke; Wendy Yang; Evan Y Snyder; Lamya S Shihabuddin
Injection of mouse and human neural stem cells into neonatal Niemann-Pick A model mice.
Brain research 2007;1140():195-204.
2007: Jean-Pyo Lee; Mylvaganam Jeyakumar; Rodolfo Gonzalez; Hiroto Takahashi; Pei-Jen Lee; Rena C Baek; Dan Clark; Heather Rose; Gerald Fu; Jonathan Clarke; Scott R McKercher; Jennifer Meerloo; Franz-Josef Muller; Kook In Park; Terry D Butters; Raymond A Dwek; Philip Schwartz; Gang Tong; David Wenger; Stuart A Lipton; Thomas N Seyfried; Frances M Platt; Evan Y Snyder
Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease.
Nature medicine 2007;13(4):439-47.
2007: Iram Ahmad; Robert E Hunter; Jonathan D Flax; Evan Y Snyder; Robert P Erickson
Neural stem cell implantation extends life in Niemann-Pick C1 mice.
Journal of applied genetics 2007;48(3):269-72.
2007: Paolo De Coppi; Georg Bartsch; M Minhaj Siddiqui; Tao Xu; Cesar C Santos; Laura Perin; Gustavo Mostoslavsky; Angéline C Serre; Evan Y Snyder; James J Yoo; Mark E Furth; Shay Soker; Anthony Atala
Isolation of amniotic stem cell lines with potential for therapy.
Nature biotechnology 2007;25(1):100-6.
2007: Ilyas Singec; Rahul Jandial; Andrew Crain; Guido Nikkhah; Evan Y Snyder
The leading edge of stem cell therapeutics.
Annual review of medicine 2007;58():313-28.
2006: Jeffrey J Yu; Xiaonan Sun; Xiangpeng Yuan; Jang-Won Lee; Evan Y Snyder; John S Yu
Immunomodulatory neural stem cells for brain tumour therapy.
Expert opinion on biological therapy 2006;6(12):1255-62.
2006: Dong-Eog Kim; Kiyoshi Tsuji; Young Ro Kim; Franz-Josef Mueller; Hyeon-Seok Eom; Evan Y Snyder; Eng H Lo; Ralph Weissleder; Dawid Schellingerhout
Neural stem cell transplant survival in brains of mice: assessing the effect of immunity and ischemia by using real-time bioluminescent imaging.
Radiology 2006;241(3):822-30.
2006: yang teng; Wei-Lee Liao; Howard Choi; Deniz Konya; Sunil Sabharwal; Robert Langer; Richard L Sidman; Evan Y Snyder; Walter R Frontera
Physical activity-mediated functional recovery after spinal cord injury: potential roles of neural stem cells.
Regenerative medicine 2006;1(6):763-76.
2006: Franz-Josef Mueller; Naira Serobyan; Ingrid Schraufstatter; Richard G DiScipio; Dustin Wakeman; Jeanne F Loring; Evan Y Snyder; Sophia K Khaldoyanidi
Adhesive interactions between human neural stem cells and inflamed human vascular endothelium are mediated by integrins.
Stem cells (Dayton, Ohio) 2006;24(11):2367-72.
2006: Ilyas Singec; Rolf Knoth; Ralf P Meyer; Jaroslaw Maciaczyk; Benedikt Volk; Guido Nikkhah; Michael Frotscher; Evan Y Snyder
Defining the actual sensitivity and specificity of the neurosphere assay in stem cell biology.
Nature methods 2006;3(10):801-6.
2006: Igor I. Katkov; Min S Kim; ruchi bajpai; Yoav S Altman; Marc Mercola; Jeanne F Loring; Alexey V Terskikh; Evan Y Snyder; Fred Levine
Cryopreservation by slow cooling with DMSO diminished production of Oct-4 pluripotency marker in human embryonic stem cells.
Cryobiology 2006;53(2):194-205.
2006: Jianxue Li; Jaime Imitola; Evan Y Snyder; Richard L Sidman
Neural stem cells rescue nervous purkinje neurons by restoring molecular homeostasis of tissue plasminogen activator and downstream targets.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(30):7839-48.
2006: Dustin R Wakeman; Andrew M Crain; Evan Y Snyder
Large animal models are critical for rationally advancing regenerative therapies.
Regenerative medicine 2006;1(4):405-13.
2006: Roseanne M Taylor; Jean-Pyo Lee; James J Palacino; Kate A Bower; Jianxue Li; marie T vanier; David A Wenger; Richard L Sidman; Evan Y Snyder
Intrinsic resistance of neural stem cells to toxic metabolites may make them well suited for cell non-autonomous disorders: evidence from a mouse model of Krabbe leukodystrophy.
Journal of neurochemistry 2006;97(6):1585-99.
2006: Stephen Yip; Roya Sabetrasekh; Richard L Sidman; Evan Y Snyder
Neural stem cells as novel cancer therapeutic vehicles.
European journal of cancer (Oxford, England : 1990) 2006;42(9):1298-308.
2006: Jianxue Li; Yinghua Ma; yang teng; Kangni Zheng; Timothy Vartanian; Evan Y Snyder; Richard L Sidman
Purkinje neuron degeneration in nervous (nr) mutant mice is mediated by a metabolic pathway involving excess tissue plasminogen activator.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(20):7847-52.
2006: Evan Y Snyder
Special issue: the intersection of stem/progenitor cell biology and hypoxic-ischemic cerebral injury/stroke.
Experimental neurology 2006;199(1):1-4.
2006: Kook In Park; Michael A Hack; Jitka Ourednik; Booma Yandava; Jonathan D Flax; Philip E Stieg; Stephen Gullans; Francis E Jensen; Richard L Sidman; Václav Ourednik; Evan Y Snyder
Acute injury directs the migration, proliferation, and differentiation of solid organ stem cells: evidence from the effect of hypoxia-ischemia in the CNS on clonal "reporter" neural stem cells.
Experimental neurology 2006;199(1):156-78.
2006: Hyoung-Tai Kim; Il-Sun Kim; Il-Shin Lee; Jean-Pyo Lee; Evan Y Snyder; Kook In Park
Human neurospheres derived from the fetal central nervous system are regionally and temporally specified but are not committed.
Experimental neurology 2006;199(1):222-35.
2006: Kook In Park; B Timothy Himes; Philip E Stieg; Alan Tessler; Itzhak Fischer; Evan Y Snyder
Neural stem cells may be uniquely suited for combined gene therapy and cell replacement: Evidence from engraftment of Neurotrophin-3-expressing stem cells in hypoxic-ischemic brain injury.
Experimental neurology 2006;199(1):179-90.
2006: yang teng; Howard Choi; Wenzheng Huang; Renna C Onario; Walter R Frontera; Evan Y Snyder; Sunil Sabharwal
Therapeutic effects of clenbuterol in a murine model of amyotrophic lateral sclerosis.
Neuroscience letters 2006;397(1-2):155-8.
2006: Asha Bakshi; Saori Shimizu; Carrie A Keck; Sean Cho; David G LeBold; Diego Morales; Ernest Arenas; Evan Y Snyder; Deborah J Watson; Tracy K McIntosh
Neural progenitor cells engineered to secrete GDNF show enhanced survival, neuronal differentiation and improve cognitive function following traumatic brain injury.
The European journal of neuroscience 2006;23(8):2119-34.
2006: Evan Y Snyder; Lawrence M Hinman; Michael W Kalichman
Can science resolve the ethical impasse in stem cell research?
Nature biotechnology 2006;24(4):397-400.
2006: Glauco R Souza; Dawn Christianson; Fernanda I Staquicini; Michael G Ozawa; Evan Y Snyder; Richard L Sidman; J Houston Miller; Wadih Arap; Renata Pasqualini
Networks of gold nanoparticles and bacteriophage as biological sensors and cell-targeting agents.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(5):1215-20.
2006: Evan Y Snyder; Jeanne F Loring
Beyond fraud--stem-cell research continues.
The New England journal of medicine 2006;354(4):321-4.
2006: Franz-Josef Müller; Evan Y Snyder; Jeanne F Loring
Gene therapy: can neural stem cells deliver?
Nature reviews. Neuroscience 2006;7(1):75-84.
2005: Asha Bakshi; Carrie A Keck; Vadim S Koshkin; David G LeBold; Robert Siman; Evan Y Snyder; Tracy K McIntosh
Caspase-mediated cell death predominates following engraftment of neural progenitor cells into traumatically injured rat brain.
Brain research 2005;1065(1-2):8-19.
2005: Michael W Kalichman; Lawrence M Hinman; Evan Y Snyder
Exploring common ground in the stem cell ethical debate--a perspective for scientists: introduction to this special issue of stem cell reviews.
Stem cell reviews 2005;1(4):285-6.
2005: Evan Y Snyder; Jeanne F Loring
A role for stem cell biology in the physiological and pathological aspects of aging.
Journal of the American Geriatrics Society 2005;53(9 Suppl):S287-91.
2005: Mark A Parker; Julia K Anderson; Deborah A Corliss; Victoria E Abraria; Richard L Sidman; Kook In Park; yang teng; Douglas A Cotanche; Evan Y Snyder
Expression profile of an operationally-defined neural stem cell clone.
Experimental neurology 2005;194(2):320-32.
2005: Franz-Josef Mueller; Scott R McKercher; Jaime Imitola; Jeanne F Loring; S Yip; Samia Khoury; Evan Y Snyder
At the interface of the immune system and the nervous system: how neuroinflammation modulates the fate of neural progenitors in vivo.
Ernst Schering Research Foundation workshop 2005;(53):83-114.
2005: Kimberly B Bjugstad; D Eugene Redmond; yang teng; John D Elsworth; Robert H Roth; Barbara C Blanchard; Evan Y Snyder; John R Sladek
Neural stem cells implanted into MPTP-treated monkeys increase the size of endogenous tyrosine hydroxylase-positive cells found in the striatum: a return to control measures.
Cell transplantation 2005;14(4):183-92.
2004: Jaime Imitola; Khadir Raddassi; Kook In Park; Franz-Josef Mueller; Marta Nieto; yang teng; Dan Frenkel; Jianxue Li; Richard L Sidman; Christopher Walsh; Evan Y Snyder; Samia J Khoury
Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(52):18117-22.
2004: Jun Yan; Annie M Welsh; Susan H Bora; Evan Y Snyder; Vassilis E Koliatsos
Differentiation and tropic/trophic effects of exogenous neural precursors in the adult spinal cord.
The Journal of comparative neurology 2004;480(1):101-14.
2004: Joost W Schouten; Carl T Fulp; Nicolas C Royo; Kathryn E Saatman; Deborah J Watson; Evan Y Snyder; John Q Trojanowski; Darwin J Prockop; Andrew I.R. Maas; Tracy K McIntosh
A review and rationale for the use of cellular transplantation as a therapeutic strategy for traumatic brain injury.
Journal of neurotrauma 2004;21(11):1501-38.
2004: Jerònia Lladó; Christine Haenggeli; Nicholas J Maragakis; Evan Y Snyder; Jeffrey rothstein
Neural stem cells protect against glutamate-induced excitotoxicity and promote survival of injured motor neurons through the secretion of neurotrophic factors.
Molecular and cellular neurosciences 2004;27(3):322-31.
2004: Jaime Imitola; Kook In Park; yang teng; Sahar Nisim; Mahesh Lachyankar; Jitka Ourednik; Franz-Josef Mueller; Rene Yiou; Anthony Atala; Richard L Sidman; Mark H Tuszynski; Samia J Khoury; Evan Y Snyder
Stem cells: cross-talk and developmental programs.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2004;359(1445):823-37.
2004: Jaime Imitola; Manuel Comabella; Anil Chandraker; Fernando Dangond; Mohamed H Sayegh; Evan Y Snyder; Samia J Khoury
Neural stem/progenitor cells express costimulatory molecules that are differentially regulated by inflammatory and apoptotic stimuli.
The American journal of pathology 2004;164(5):1615-25.
2004: Evan Y Snyder; George Q Daley; Margaret Goodell
Taking stock and planning for the next decade: realistic prospects for stem cell therapies for the nervous system.
Journal of neuroscience research 2004;76(2):157-68.
2004: yang teng; Howard Choi; Renna C Onario; Shan Zhu; Federico C Desilets; Shoumin Lan; Eric J Woodard; Evan Y Snyder; Marc E Eichler; Robert M Friedlander
Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(9):3071-6.
2004: Jeffrey rothstein; Evan Y Snyder
Reality and immortality--neural stem cells for therapies.
Nature biotechnology 2004;22(3):283-5.
2004: Carla B Mellough; Qi Cui; Kirsty L Spalding; Natalie A Symons; Margaret A Pollett; Evan Y Snyder; Jeffrey D Macklis; Alan R Harvey
Fate of multipotent neural precursor cells transplanted into mouse retina selectively depleted of retinal ganglion cells.
Experimental neurology 2004;186(1):6-19.
2003: John A Boockvar; Dmitri Kapitonov; Gurpreet S Kapoor; Joost Schouten; George J Counelis; Oliver Bogler; Evan Y Snyder; Tracy K McIntosh; Donald M O'Rourke
Constitutive EGFR signaling confers a motile phenotype to neural stem cells.
Molecular and cellular neurosciences 2003;24(4):1116-30.
2003: Jaime Imitola; Evan Y Snyder; Samia J Khoury
Genetic programs and responses of neural stem/progenitor cells during demyelination: potential insights into repair mechanisms in multiple sclerosis.
Physiological genomics 2003;14(3):171-97.
2003: Stephen Yip; Karen S Aboody; Michael Burns; Jaime Imitola; John A Boockvar; Jennifer Allport; Kook In Park; yang teng; Mahesh Lachyankar; Tracy McIntosh; Donald M O'Rourke; Samia Khoury; Ralph Weissleder; Peter Black; William Weiss; Evan Y Snyder
Neural stem cell biology may be well suited for improving brain tumor therapies.
Cancer journal (Sudbury, Mass.) 2003;9(3):189-204.
2003: George Q Daley; Margaret A Goodell; Evan Y Snyder
Realistic prospects for stem cell therapeutics.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2003;():398-418.
2002: Kook In Park; yang teng; Evan Y Snyder
The injured brain interacts reciprocally with neural stem cells supported by scaffolds to reconstitute lost tissue.
Nature biotechnology 2002;20(11):1111-7.
2002: Jitka Ourednik; Václav Ourednik; William P Lynch; Melitta Schachner; Evan Y Snyder
Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons.
Nature biotechnology 2002;20(11):1103-10.
2002: Peter Riess; Chen Zhang; Kathryn E Saatman; Helmut L Laurer; Luca Longhi; Ramesh Raghupathi; Philipp M Lenzlinger; Jonathan Lifshitz; John A Boockvar; Edmund A M Neugebauer; Evan Y Snyder; Tracy K McIntosh
Transplanted neural stem cells survive, differentiate, and improve neurological motor function after experimental traumatic brain injury.
Neurosurgery 2002;51(4):1043-52; discussion 1052-4.
2002: Ming Yang; Natalie D Stull; Mathew A Berk; Evan Y Snyder; Lorraine Iacovitti
Neural stem cells spontaneously express dopaminergic traits after transplantation into the intact or 6-hydroxydopamine-lesioned rat.
Experimental neurology 2002;177(1):50-60.
2002: Evan Y Snyder; Kook In Park
Limitations in brain repair.
Nature medicine 2002;8(9):928-30.
2002: Kook In Park; Jitka Ourednik; Václav Ourednik; R M Taylor; Karen S Aboody; K I Auguste; Mahesh Lachyankar; D Eugene Redmond; Evan Y Snyder
Global gene and cell replacement strategies via stem cells.
Gene therapy 2002;9(10):613-24.
2002: Piotr Zlomanczuk; Maciej Mrugala; Horacio O de la Iglesia; Václav Ourednik; Peter J Quesenberry; Evan Y Snyder; William J Schwartz
Transplanted clonal neural stem-like cells respond to remote photic stimulation following incorporation within the suprachiasmatic nucleus.
Experimental neurology 2002;174(2):162-8.
2002: yang teng; Erin Lavik; Xianlu Qu; Kook In Park; Jitka Ourednik; David Zurakowski; Robert Langer; Evan Y Snyder
Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3024-9.
2002: Kook In Park; Mahesh Lachyankar; Sahar Nissim; Evan Y Snyder
Neural stem cells for CNS repair: state of the art and future directions.
Advances in experimental medicine and biology 2002;506(Pt B):1291-6.
2001: B Timothy Himes; Y Liu; Joanna M Solowska; Evan Y Snyder; Itzhak Fischer; Alan Tessler
Transplants of cells genetically modified to express neurotrophin-3 rescue axotomized Clarke's nucleus neurons after spinal cord hemisection in adult rats.
Journal of neuroscience research 2001;65(6):549-64.
2001: Václav Ourednik; Jitka Ourednik; Jonathan D Flax; W Michael Zawada; Cindy Hutt; C Yang; Kook In Park; Seung Kim; Richard L Sidman; Curt R Freed; Evan Y Snyder
Segregation of human neural stem cells in the developing primate forebrain.
Science (New York, N.Y.) 2001;293(5536):1820-4.
2000: Karen S Aboody; A Brown; Nikolai G Rainov; K A Bower; S Liu; W Yang; J E Small; Ulrich Herrlinger; Václav Ourednik; Peter Black; Xandra O Breakefield; Evan Y Snyder
Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(23):12846-51.
1999: David H Rowitch; B S-Jacques; SM Lee; Jonathan D Flax; Evan Y Snyder; Andrew P McMahon
Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(20):8954-65.
1999: Václav Ourednik; Jitka Ourednik; Kook In Park; Evan Y Snyder
Neural stem cells -- a versatile tool for cell replacement and gene therapy in the central nervous system.
Clinical genetics 1999;56(4):267-78.
1999: Kook In Park; S Liu; Jonathan D Flax; S Nissim; Philip E Stieg; Evan Y Snyder
Transplantation of neural progenitor and stem cells: developmental insights may suggest new therapies for spinal cord and other CNS dysfunction.
Journal of neurotrauma 1999;16(8):675-87.
1999: Y Liu; B Timothy Himes; Joanna M Solowska; J Moul; SY Chow; Kook In Park; Alan Tessler; Marion Murray; Evan Y Snyder; Itzhak Fischer
Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovirus.
Experimental neurology 1999;158(1):9-26.
1999: Booma Yandava; LL Billinghurst; Evan Y Snyder
"Global" cell replacement is feasible via neural stem cell transplantation: evidence from the dysmyelinated shiverer mouse brain.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):7029-34.
1998: Jonathan D Flax; S Aurora; C Yang; C Simonin; A M Wills; LL Billinghurst; M Jendoubi; Richard L Sidman; J H Wolfe; Seung Kim; Evan Y Snyder
Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes.
Nature biotechnology 1998;16(11):1033-9.
1998: LL Billinghurst; R M Taylor; Evan Y Snyder
Remyelination: cellular and gene therapy.
Seminars in pediatric neurology 1998;5(3):211-28.
1997: C M Rosario; Booma Yandava; Bela Kosaras; D Zurakowski; Richard L Sidman; Evan Y Snyder
Differentiation of engrafted multipotent neural progenitors towards replacement of missing granule neurons in meander tail cerebellum may help determine the locus of mutant gene action.
Development (Cambridge, England) 1997;124(21):4213-24.
1997: Evan Y Snyder; C Yoon; Jonathan D Flax; Jeffrey D Macklis
Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(21):11663-8.
1997: R M Taylor; Evan Y Snyder
Widespread engraftment of neural progenitor and stem-like cells throughout the mouse brain.
Transplantation proceedings 1997;29(1-2):845-7.
1997: Evan Y Snyder; M C Senut
The use of nonneuronal cells for gene delivery.
Neurobiology of disease 1997;4(2):69-102.
1997: Evan Y Snyder; Kook In Park; Jonathan D Flax; S Liu; C M Rosario; Booma Yandava; S Aurora
Potential of neural "stem-like" cells for gene therapy and repair of the degenerating central nervous system.
Advances in neurology 1997;72():121-32.
1996: Evan Y Snyder; L J Fisher
Gene therapy in neurology.
Current opinion in pediatrics 1996;8(6):558-68.
1996: Evan Y Snyder; J H Wolfe
Central nervous system cell transplantation: a novel therapy for storage diseases?
Current opinion in neurology 1996;9(2):126-36.
1996: H D Lacorazza; Jonathan D Flax; Evan Y Snyder; Moncef Jendoubi
Expression of human beta-hexosaminidase alpha-subunit gene (the gene defect of Tay-Sachs disease) in mouse brains upon engraftment of transduced progenitor cells.
Nature medicine 1996;2(4):424-9.
1995: Evan Y Snyder
Immortalized neural stem cells: insights into development; prospects for gene therapy and repair.
Proceedings of the Association of American Physicians 1995;107(2):195-204.
1995: Evan Y Snyder; R M Taylor; J H Wolfe
Neural progenitor cell engraftment corrects lysosomal storage throughout the MPS VII mouse brain.
Nature 1995;374(6520):367-70.
1995: Evan Y Snyder; Jeffrey D Macklis
Multipotent neural progenitor or stem-like cells may be uniquely suited for therapy for some neurodegenerative conditions.
Clinical neuroscience (New York, N.Y.) 1995;3(5):310-6.
1994: Evan Y Snyder
Grafting immortalized neurons to the CNS.
Current opinion in neurobiology 1994;4(5):742-51.
1992: Evan Y Snyder
Neural transplantation: an approach to cellular plasticity in the developing central nervous system.
Seminars in perinatology 1992;16(2):106-21.
1992: Evan Y Snyder; D L Deitcher; C Walsh; S Arnold-Aldea; E A Hartwieg; Constance L Cepko
Multipotent neural cell lines can engraft and participate in development of mouse cerebellum.
Cell 1992;68(1):33-51.
1990: David L Turner; Evan Y Snyder; Constance L Cepko
Lineage-independent determination of cell type in the embryonic mouse retina.
Neuron 1990;4(6):833-45.
1990: E F Ryder; Evan Y Snyder; Constance L Cepko
Establishment and characterization of multipotent neural cell lines using retrovirus vector-mediated oncogene transfer.
Journal of neurobiology 1990;21(2):356-75.