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Joseph Sodroski

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TOP 3
Halima Medjahed; Beatriz Pacheco; Joseph Sodroski; Anik Désormeaux; Andrés Finzi
The HIV-1 gp120 major variable regions modulate cold inactivation.
Christopher Tipper; Joseph Sodroski
Enhanced autointegration in hyperstable simian immunodeficiency virus capsid mutants blocked after reverse transcription.
Shi-Hua Xiang; Wen Yuan; Dane Bowder; Beatriz Pacheco; Joseph Sodroski
Characterization of a dual-tropic human immunodeficiency virus (HIV-1) strain derived from the prototypical X4 isolate HXBc2.

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All Publications

2013: Halima Medjahed; Beatriz Pacheco; Joseph Sodroski; Anik Désormeaux; Andrés Finzi
The HIV-1 gp120 major variable regions modulate cold inactivation.
Journal of virology 2013;87(7):4103-11.
2013: Christopher Tipper; Joseph Sodroski
Enhanced autointegration in hyperstable simian immunodeficiency virus capsid mutants blocked after reverse transcription.
Journal of virology 2013;87(7):3628-39.
2013: Shi-Hua Xiang; Wen Yuan; Dane Bowder; Beatriz Pacheco; Joseph Sodroski
Characterization of a dual-tropic human immunodeficiency virus (HIV-1) strain derived from the prototypical X4 isolate HXBc2.
Virology 2013;438(1):5-13.
2013: Anik Désormeaux; Mathieu Coutu; Christopher Gu; Alon Herschhorn; Youdong Mao; Halima Medjahed; Beatriz Pacheco; Joseph Sodroski; Shi-Hua Xiang; Andrés Finzi
The highly conserved layer-3 component of the HIV-1 gp120 inner domain is critical for CD4-required conformational transitions.
Journal of virology 2013;87(5):2549-62.
2013: Hillel Haim; Ignacio Salas; Joseph Sodroski
Proteolytic processing of the human immunodeficiency virus envelope glycoprotein precursor decreases conformational flexibility.
Journal of virology 2013;87(3):1884-9.
2013: Ferit Tuzer; Elizabeth Upton; Isaac Zentner; Mark Contarino; Andrew Holmes; Kantharaju Kamanna; Judith LaLonde; Navid Madani; Karyn McFadden; Srivats Rajagopal; Joseph Sodroski; Irwin Chaiken
HIV-1 Env gp120 structural determinants for peptide triazole dual receptor site antagonism.
Proteins 2013;81(2):271-90.
2012: Youdong Mao; Christopher Gu; Hillel Haim; Alon Herschhorn; Liping Wang; Shi-Hua Xiang; Xinzhen Yang; Joseph Sodroski
Subunit organization of the membrane-bound HIV-1 envelope glycoprotein trimer.
Nature structural & molecular biology 2012;19(9):893-9.
2012: Andrés Finzi; Alon Herschhorn; Peter D Kwong; Beatriz Pacheco; Marie Pancera; Liping Wang; Shi-Hua Xiang; Xing Zeng; Anik Desormeaux; Joseph Sodroski
Lineage-specific differences between human and simian immunodeficiency virus regulation of gp120 trimer association and CD4 binding.
Journal of virology 2012;86(17):8974-86.
2012: Sandhya Kortagere; Fred C Krebs; Navid Madani; Marie K Mankowski; Julio Martín-García; Apara Oza; Shendra R Passic; Amy Princiotto; Roger G Ptak; Arne Schön; Luz-Jeannette Sierra; Kevin Anthony; Simon Cocklin; Ernesto Freire; David M Jones; Joseph Sodroski; Eric Stavale; Gokul Swaminathan; Xiaozhao Wang; Isaac Zentner; Amos B Smith
Inhibiting early-stage events in HIV-1 replication by small-molecule targeting of the HIV-1 capsid.
Journal of virology 2012;86(16):8472-81.
2012: Judith M LaLonde; Navid Madani; John R Mascola; Amy M Princiotto; Arne Schön; Joel R Courter; Ernesto Freire; David M Jones; Toyoharu Kobayashi; Young Do Kwon; Peter D Kwong; Joseph Sodroski; Takahiro Soeta; Alexander W Sun; Xueling Wu; Amos B Smith
Structure-based design, synthesis, and characterization of dual hotspot small-molecule HIV-1 entry inhibitors.
Journal of medicinal chemistry 2012;55(9):4382-96.
2012: Ke Zhuang; Andres Finzi; Arne Frantzell; Wei Huang; Joseph Sodroski; Jonathan Toma; Cecilia Cheng-Mayer
Identification of interdependent variables that influence coreceptor switch in R5 SHIV(SF162P3N)-infected macaques.
Retrovirology 2012;9():106.
2011: Nikita K Malavia; Amy M Princiotto; Avi Schroeder; Joseph Sodroski; David Zurakowski; Hila E Barash; Robert Langer; Anna R Laury; Navid Madani; Daniel S Kohane
Liposomes for HIV prophylaxis.
Biomaterials 2011;32(33):8663-8.
2011: Craig B Wilen; Jason A Wojcechowskyj; Julie M Decker; Beatrice H Hahn; Hillel Haim; Barton F Haynes; Elizabeth A Henning; David C Montefiori; Nicholas F Parrish; Josiah E Petersen; Jennifer M Pfaff; George M Shaw; Joseph Sodroski; John C Tilton; Robert W Doms
Phenotypic and immunologic comparison of clade B transmitted/founder and chronic HIV-1 envelope glycoproteins.
Journal of virology 2011;85(17):8514-27.
2011: Xing Li; Ann M Fiegen; Darwin F Yeung; Joseph Sodroski
Determinants of the higher order association of the restriction factor TRIM5alpha and other tripartite motif (TRIM) proteins.
The Journal of biological chemistry 2011;286(32):27959-70.
2011: Jonghwa Kim; Christopher Tipper; Joseph Sodroski
Role of TRIM5α RING domain E3 ubiquitin ligase activity in capsid disassembly, reverse transcription blockade, and restriction of simian immunodeficiency virus.
Journal of virology 2011;85(16):8116-32.
2011: Hillel Haim; Aemro Kassa; Navid Madani; Kathleen McGee; Beatriz Pacheco; Amy Princiotto; Michael S Seaman; Amos B Smith; Bettina Strack; Liping Wang; Joel R Courter; Joseph Sodroski
Contribution of intrinsic reactivity of the HIV-1 envelope glycoproteins to CD4-independent infection and global inhibitor sensitivity.
PLoS pathogens 2011;7(6):e1002101.
2011: Felipe Diaz-Griffero; Daniel E Gallo; Thomas J Hope; Joseph Sodroski
Trafficking of some old world primate TRIM5α proteins through the nucleus.
Retrovirology 2011;8():38.
2011: Alak K. Kar; Youdong Mao; Gregory Bird; Loren Walensky; Joseph Sodroski
Characterization of a core fragment of the rhesus monkey TRIM5α protein.
BMC biochemistry 2011;12():1.
2011: Judith M Lalonde; Mark A Elban; Joel R Courter; Akihiro Sugawara; Takahiro Soeta; Navid Madani; Amy M Princiotto; Young Do Kwon; Peter D Kwong; Arne Schön; Ernesto Freire; Joseph Sodroski; Amos B Smith
Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening.
Bioorganic & medicinal chemistry 2011;19(1):91-101.
2010: Beatriz Pacheco; Andrés Finzi; Matthew Stremlau; Joseph Sodroski
Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α.
Virology 2010;408(2):204-12.
2010: Andrés Finzi; Beatriz Pacheco; Xin Zeng; Young Do Kwon; Peter D Kwong; Joseph Sodroski
Conformational characterization of aberrant disulfide-linked HIV-1 gp120 dimers secreted from overexpressing cells.
Journal of virological methods 2010;168(1-2):155-61.
2010: Tongqing Zhou; Ivelin Georgiev; Xueling Wu; Zhi-Yong Yang; Kaifan Dai; Andrés Finzi; Young Do Kwon; Johannes F Scheid; Wei Shi; Ling Xu; Yongping Yang; Jiang Zhu; Michel C Nussenzweig; Joseph Sodroski; Lawrence Shapiro; Gary Nabel; John R Mascola; Peter D Kwong
Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01.
Science (New York, N.Y.) 2010;329(5993):811-7.
2010: Beatriz Pacheco; Andrés Finzi; Kathleen McGee-Estrada; Joseph Sodroski
Species-specific inhibition of foamy viruses from South American monkeys by New World Monkey TRIM5{alpha} proteins.
Journal of virology 2010;84(8):4095-9.
2010: Shi-Hua Xiang; Andrés Finzi; Beatriz Pacheco; Kevin Alexander; Wen Yuan; Carlo D Rizzuto; Chih-Chin Huang; Peter D Kwong; Joseph Sodroski
A V3 loop-dependent gp120 element disrupted by CD4 binding stabilizes the human immunodeficiency virus envelope glycoprotein trimer.
Journal of virology 2010;84(7):3147-61.
2010: KyeongEun Lee; Zandrea Ambrose; Thomas D Martin; Ilker Oztop; Alok Mulky; John G Julias; Nick Vandegraaff; Joerg G Baumann; Rui Wang; Wendy Yuen; Taichiro Takemura; Kenneth Shelton; Ichiro Taniuchi; Yuan Li; Joseph Sodroski; Dan R Littman; John M Coffin; Stephen H Hughes; Derya Unutmaz; Alan Engelman; Vineet N KewalRamani
Flexible use of nuclear import pathways by HIV-1.
Cell host & microbe 2010;7(3):221-33.
2010: Andrés Finzi; Shi-Hua Xiang; Beatriz Pacheco; Liping Wang; Jessica Haight; Aemro Kassa; Brenda Danek; Marie Pancera; Peter D Kwong; Joseph Sodroski
Topological layers in the HIV-1 gp120 inner domain regulate gp41 interaction and CD4-triggered conformational transitions.
Molecular cell 2010;37(5):656-67.
2010: Marie Pancera; Shahzad Majeed; Yih-En Andrew Ban; Lei Chen; Chih-chin Huang; Leopold Kong; Young Do Kwon; Jonathan Stuckey; Tongqing Zhou; James E Robinson; William R Schief; Joseph Sodroski; Richard Wyatt; Peter D Kwong
Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(3):1166-71.
2010: Mikhail A Zhukovsky; Stéphane Basmaciogullari; Beatriz Pacheco; Liping Wang; Navid Madani; Hillel Haim; Joseph Sodroski
Thermal stability of the human immunodeficiency virus type 1 (HIV-1) receptors, CD4 and CXCR4, reconstituted in proteoliposomes.
PloS one 2010;5(10):e13249.
2010: So-Yon Lim; Thomas Rogers; Tiffany Chan; James B Whitney; Jonghwa Kim; Joseph Sodroski; Norman L Letvin
TRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus Monkeys.
PLoS pathogens 2010;6(1):e1000738.
2009: Lei Chen; Young Do Kwon; Tongqing Zhou; Xueling Wu; Sijy O'Dell; Lisa Cavacini; Ann J Hessell; Marie Pancera; Min Tang; Ling Xu; Zhi-Yong Yang; Mei-Yun Zhang; James Arthos; Dennis R Burton; Dimiter S Dimitrov; Gary Nabel; Marshall R Posner; Joseph Sodroski; Richard Wyatt; John R Mascola; Peter D Kwong
Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Science (New York, N.Y.) 2009;326(5956):1123-7.
2009: Yuan Li; Alak K. Kar; Joseph Sodroski
Target cell type-dependent modulation of human immunodeficiency virus type 1 capsid disassembly by cyclophilin A.
Journal of virology 2009;83(21):10951-62.
2009: Felipe Diaz-Griffero; Xu-rong Qin; Fumiaki Hayashi; Takanori Kigawa; Andres Finzi; Zoe Sarnak; Maritza Lienlaf; Shigeyuki Yokoyama; Joseph Sodroski
A B-box 2 surface patch important for TRIM5alpha self-association, capsid binding avidity, and retrovirus restriction.
Journal of virology 2009;83(20):10737-51.
2009: Aemro Kassa; Navid Madani; Arne Schön; Hillel Haim; Andrés Finzi; Shi-Hua Xiang; Liping Wang; Amy Princiotto; Marie Pancera; Joel Courter; Amos B Smith; Ernesto Freire; Peter D Kwong; Joseph Sodroski
Transitions to and from the CD4-bound conformation are modulated by a single-residue change in the human immunodeficiency virus type 1 gp120 inner domain.
Journal of virology 2009;83(17):8364-78.
2009: Judith N Torimiro; Hassan Javanbakht; Felipe Diaz-Griffero; Jonghwa Kim; Jean K Carr; Mary Carrington; Julie Sawitzke; Donald S. Burke; Nathan D Wolfe; Michael Dean; Joseph Sodroski
A rare null allele potentially encoding a dominant-negative TRIM5alpha protein in Baka pygmies.
Virology 2009;391(1):140-7.
2009: Aemro Kassa; Andrés Finzi; Marie Pancera; Joel R Courter; Amos B Smith; Joseph Sodroski
Identification of a human immunodeficiency virus type 1 envelope glycoprotein variant resistant to cold inactivation.
Journal of virology 2009;83(9):4476-88.
2009: Hillel Haim; Zhihai Si; Navid Madani; Liping Wang; Joel R Courter; Amy Princiotto; Aemro Kassa; Marciella DeGrace; Kathleen McGee-Estrada; Megan Mefford; Dana Gabuzda; Amos B Smith; Joseph Sodroski
Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state.
PLoS pathogens 2009;5(4):e1000360.
2009: Wen Yuan; Xing Li; Marta Kasterka; Miroslaw K Gorny; Susan Zolla-Pazner; Joseph Sodroski
Oligomer-specific conformations of the human immunodeficiency virus (HIV-1) gp41 envelope glycoprotein ectodomain recognized by human monoclonal antibodies.
AIDS research and human retroviruses 2009;25(3):319-28.
2008: Xing Li; Joseph Sodroski
The TRIM5alpha B-box 2 domain promotes cooperative binding to the retroviral capsid by mediating higher-order self-association.
Journal of virology 2008;82(23):11495-502.
2008: Alak K. Kar; Felipe Diaz-Griffero; Yuan Li; Xing Li; Joseph Sodroski
Biochemical and biophysical characterization of a chimeric TRIM21-TRIM5alpha protein.
Journal of virology 2008;82(23):11669-81.
2008: Navid Madani; Arne Schön; Amy M Princiotto; Judith M Lalonde; Joel R Courter; Takahiro Soeta; Danny Ng; Liping Wang; Evan T Brower; Shi-Hua Xiang; Young Do Kwon; Chih-Chin Huang; Richard Wyatt; Peter D Kwong; Ernesto Freire; Amos B Smith; Joseph Sodroski
Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120.
Structure (London, England : 1993) 2008;16(11):1689-701.
2008: Max W Richardson; Richard G Carroll; Matthew Stremlau; Nikolay Korokhov; Laurent M Humeau; Guido Silvestri; Joseph Sodroski; James L Riley
Mode of transmission affects the sensitivity of human immunodeficiency virus type 1 to restriction by rhesus TRIM5alpha.
Journal of virology 2008;82(22):11117-28.
2008: Felipe Diaz-Griffero; Michel Perron; Kathleen McGee-Estrada; Robert Hanna; Pierre V Maillard; Didier Trono; Joseph Sodroski
A human TRIM5alpha B30.2/SPRY domain mutant gains the ability to restrict and prematurely uncoat B-tropic murine leukemia virus.
Virology 2008;378(2):233-42.
2008: Hosahudya Gopi; M Umashankara; Vanessa Pirrone; Judith LaLonde; Navid Madani; Ferit Tuzer; Sabine Baxter; Isaac Zentner; Simon Cocklin; Navneet Jawanda; Shendra R Miller; Arne Schön; Jeffrey C Klein; Ernesto Freire; Fred C Krebs; Amos B Smith; Joseph Sodroski; Irwin Chaiken
Structural determinants for affinity enhancement of a dual antagonist peptide entry inhibitor of human immunodeficiency virus type-1.
Journal of medicinal chemistry 2008;51(9):2638-47.
2008: Gunilla B Karlsson Hedestam; Ron A M Fouchier; Sanjay Phogat; Dennis R Burton; Joseph Sodroski; Richard Wyatt
The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus.
Nature reviews. Microbiology 2008;6(2):143-55.
2008: Beatriz Pacheco; Stéphane Basmaciogullari; Jason A LaBonte; Shi-Hua Xiang; Joseph Sodroski
Adaptation of the human immunodeficiency virus type 1 envelope glycoproteins to new world monkey receptors.
Journal of virology 2008;82(1):346-57.
2007: Felipe Diaz-Griffero; Alak K. Kar; Mark Lee; Matthew Stremlau; Eric M Poeschla; Joseph Sodroski
Comparative requirements for the restriction of retrovirus infection by TRIM5alpha and TRIMCyp.
Virology 2007;369(2):400-10.
2007: Damodara Rao Mendu; Hermann Katinger; Joseph Sodroski; Kwang S Kim
HIV-1 envelope protein gp140 binding studies to human brain microvascular endothelial cells.
Biochemical and biophysical research communications 2007;363(3):466-71.
2007: Hassan Javanbakht; Felipe Diaz-Griffero; Wen Yuan; Darwin F Yeung; Xing Li; Byeongwoon Song; Joseph Sodroski
The ability of multimerized cyclophilin A to restrict retrovirus infection.
Virology 2007;367(1):19-29.
2007: Dongxiang Liu; Navid Madani; Ying Li; Rong Cao; Won-Tak Choi; Sameer P Kawatkar; Mi Youn Lim; Santosh Kumar; Chang-Zhi Dong; Jun Wang; Julie D Russell; Caroline R Lefebure; Jing An; Scott Wilson; Yi-Gui Gao; Luke A Pallansch; Joseph Sodroski; Ziwei Huang
Crystal structure and structural mechanism of a novel anti-human immunodeficiency virus and D-amino acid-containing chemokine.
Journal of virology 2007;81(20):11489-98.
2007: Felipe Diaz-Griffero; Alak K. Kar; Michel Perron; Shi-Hua Xiang; Hassan Javanbakht; Xing Li; Joseph Sodroski
Modulation of retroviral restriction and proteasome inhibitor-resistant turnover by changes in the TRIM5alpha B-box 2 domain.
Journal of virology 2007;81(19):10362-78.
2007: Xing Li; Byeongwoon Song; Shi-Hua Xiang; Joseph Sodroski
Functional interplay between the B-box 2 and the B30.2(SPRY) domains of TRIM5alpha.
Virology 2007;366(2):234-44.
2007: Chih-Chin Huang; Son N Lam; Priyamvada Acharya; Min Tang; Shi-Hua Xiang; Syed Shahzad-Ul Hussan; Robyn L Stanfield; James Robinson; Joseph Sodroski; Ian A Wilson; Richard Wyatt; Carole A Bewley; Peter D Kwong
Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4.
Science (New York, N.Y.) 2007;317(5846):1930-4.
2007: Xinzhen Yang; Inna Lipchina; Michelle A Lifton; Liping Wang; Joseph Sodroski
Antibody binding in proximity to the receptor/glycoprotein complex leads to a basal level of virus neutralization.
Journal of virology 2007;81(16):8809-13.
2007: J Wesley Ulm; Michel Perron; Joseph Sodroski; Richard C Mulligan
Complex determinants within the Moloney murine leukemia virus capsid modulate susceptibility of the virus to Fv1 and Ref1-mediated restriction.
Virology 2007;363(2):245-55.
2007: Barna Dey; Marie Pancera; Krisha Svehla; Yuuei Shu; Shi-Hua Xiang; Jeffrey Vainshtein; Yuxing Li; Joseph Sodroski; Peter D Kwong; John R Mascola; Richard Wyatt
Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: antigenicity, biophysics, and immunogenicity.
Journal of virology 2007;81(11):5579-93.
2007: Xing Li; Bert Gold; Colm O'hUigin; Felipe Diaz-Griffero; Byeongwoon Song; Zhihai Si; Yuan Li; Wen Yuan; Matthew Stremlau; Claudia C Mische; Hassan Javanbakht; Mark Scally; Cheryl A Winkler; Michael Dean; Joseph Sodroski
Unique features of TRIM5alpha among closely related human TRIM family members.
Virology 2007;360(2):419-33.
2007: Michel Perron; Matthew Stremlau; Mark Lee; Hassan Javanbakht; Byeongwoon Song; Joseph Sodroski
The human TRIM5alpha restriction factor mediates accelerated uncoating of the N-tropic murine leukemia virus capsid.
Journal of virology 2007;81(5):2138-48.
2007: Tongqing Zhou; Ling Xu; Barna Dey; Ann J Hessell; Donald Van Ryk; Shi-Hua Xiang; Xinzhen Yang; Mei-Yun Zhang; Michael B Zwick; James Arthos; Dennis R Burton; Dimiter S Dimitrov; Joseph Sodroski; Richard Wyatt; Gary Nabel; Peter D Kwong
Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature 2007;445(7129):732-7.
2007: Navid Madani; Amy M Hubicki; Ana Luisa Perdigoto; Martin Springer; Joseph Sodroski
Inhibition of human immunodeficiency virus envelope glycoprotein- mediated single cell lysis by low-molecular-weight antagonists of viral entry.
Journal of virology 2007;81(2):532-8.
2006: Xinzhen Yang; Inna Lipchina; Simon Cocklin; Irwin Chaiken; Joseph Sodroski
Antibody binding is a dominant determinant of the efficiency of human immunodeficiency virus type 1 neutralization.
Journal of virology 2006;80(22):11404-8.
2006: Hassan Javanbakht; Ping An; Bert Gold; Desiree C Petersen; Colm O'hUigin; George W Nelson; Stephen J O'Brien; Gregory D Kirk; Roger Detels; Susan Buchbinder; Sharyne Donfield; Sergey Shulenin; Byeongwoon Song; Michel Perron; Matthew Stremlau; Joseph Sodroski; Michael Dean; Cheryl A Winkler
Effects of human TRIM5alpha polymorphisms on antiretroviral function and susceptibility to human immunodeficiency virus infection.
Virology 2006;354(1):15-27.
2006: Stéphane Basmaciogullari; Beatriz Pacheco; Stephan Bour; Joseph Sodroski
Specific interaction of CXCR4 with CD4 and CD8alpha: functional analysis of the CD4/CXCR4 interaction in the context of HIV-1 envelope glycoprotein-mediated membrane fusion.
Virology 2006;353(1):52-67.
2006: Hassan Javanbakht; Wen Yuan; Darwin F Yeung; Byeongwoon Song; Felipe Diaz-Griffero; Yuan Li; Xing Li; Matthew Stremlau; Joseph Sodroski
Characterization of TRIM5alpha trimerization and its contribution to human immunodeficiency virus capsid binding.
Virology 2006;353(1):234-46.
2006: Arne Schön; Navid Madani; Jeffrey C Klein; Amy Hubicki; Danny Ng; Xinzhen Yang; Amos B Smith; Joseph Sodroski; Ernesto Freire
Thermodynamics of binding of a low-molecular-weight CD4 mimetic to HIV-1 gp120.
Biochemistry 2006;45(36):10973-80.
2006: Felipe Diaz-Griffero; Nick Vandegraaff; Yuan Li; Kathleen McGee-Estrada; Matthew Stremlau; Sohanya Welikala; Zhihai Si; Alan Engelman; Joseph Sodroski
Requirements for capsid-binding and an effector function in TRIMCyp-mediated restriction of HIV-1.
Virology 2006;351(2):404-19.
2006: Matthew Stremlau; Byeongwoon Song; Hassan Javanbakht; Michel Perron; Joseph Sodroski
Cyclophilin A: an auxiliary but not necessary cofactor for TRIM5alpha restriction of HIV-1.
Virology 2006;351(1):112-20.
2006: Yuan Li; Xing Li; Matthew Stremlau; Mark Lee; Joseph Sodroski
Removal of arginine 332 allows human TRIM5alpha to bind human immunodeficiency virus capsids and to restrict infection.
Journal of virology 2006;80(14):6738-44.
2006: Wen Yuan; Jessica Bazick; Joseph Sodroski
Characterization of the multiple conformational States of free monomeric and trimeric human immunodeficiency virus envelope glycoproteins after fixation by cross-linker.
Journal of virology 2006;80(14):6725-37.
2006: Xing Li; Yuan Li; Matthew Stremlau; Wen Yuan; Byeongwoon Song; Michel Perron; Joseph Sodroski
Functional replacement of the RING, B-box 2, and coiled-coil domains of tripartite motif 5alpha (TRIM5alpha) by heterologous TRIM domains.
Journal of virology 2006;80(13):6198-206.
2006: Felipe Diaz-Griffero; Xing Li; Hassan Javanbakht; Byeongwoon Song; Sohanya Welikala; Matthew Stremlau; Joseph Sodroski
Rapid turnover and polyubiquitylation of the retroviral restriction factor TRIM5.
Virology 2006;349(2):300-15.
2006: Michel Perron; Matthew Stremlau; Joseph Sodroski
Two surface-exposed elements of the B30.2/SPRY domain as potency determinants of N-tropic murine leukemia virus restriction by human TRIM5alpha.
Journal of virology 2006;80(11):5631-6.
2006: Zhihai Si; Nick Vandegraaff; Colm O'hUigin; Byeongwoon Song; Wen Yuan; Chen Xu; Michel Perron; Xing Li; Wayne A Marasco; Alan Engelman; Michael Dean; Joseph Sodroski
Evolution of a cytoplasmic tripartite motif (TRIM) protein in cows that restricts retroviral infection.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(19):7454-9.
2006: Xinzhen Yang; Svetla Kurteva; Xinping Ren; Sandra Lee; Joseph Sodroski
Subunit stoichiometry of human immunodeficiency virus type 1 envelope glycoprotein trimers during virus entry into host cells.
Journal of virology 2006;80(9):4388-95.
2006: Matthew Stremlau; Michel Perron; Mark Lee; Yuan Li; Byeongwoon Song; Hassan Javanbakht; Felipe Diaz-Griffero; Donovan J Anderson; Wesley I Sundquist; Joseph Sodroski
Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(14):5514-9.
2006: Santosh Kumar; Won-Tak Choi; Chang-Zhi Dong; Navid Madani; Shaomin Tian; Dongxiang Liu; Youli Wang; James Pesavento; Jun Wang; Xuejun Fan; Jian Yuan; Wayne R Fritzsche; Jing An; Joseph Sodroski; Douglas D Richman; Ziwei Huang
SMM-chemokines: a class of unnatural synthetic molecules as chemical probes of chemokine receptor biology and leads for therapeutic development.
Chemistry & biology 2006;13(1):69-79.
2005: Byeongwoon Song; Felipe Diaz-Griffero; Do Hyun Park; Thomas Rogers; Matthew Stremlau; Joseph Sodroski
TRIM5alpha association with cytoplasmic bodies is not required for antiretroviral activity.
Virology 2005;343(2):201-11.
2005: Chang-Zhi Dong; Santosh Kumar; Won-Tak Choi; Navid Madani; Shaomin Tian; Jing An; Joseph Sodroski; Ziwei Huang
Different stereochemical requirements for CXCR4 binding and signaling functions as revealed by an anti-HIV, D-amino acid-containing SMM-chemokine ligand.
Journal of medicinal chemistry 2005;48(25):7923-4.
2005: Won-Tak Choi; Shaomin Tian; Chang-Zhi Dong; Santosh Kumar; Dongxiang Liu; Navid Madani; Jing An; Joseph Sodroski; Ziwei Huang
Unique ligand binding sites on CXCR4 probed by a chemical biology approach: implications for the design of selective human immunodeficiency virus type 1 inhibitors.
Journal of virology 2005;79(24):15398-404.
2005: Chih-chin Huang; Min Tang; Mei-Yun Zhang; Shahzad Majeed; Elizabeth Montabana; Robyn L Stanfield; Dimiter S Dimitrov; Bette Korber; Joseph Sodroski; Ian A Wilson; Richard Wyatt; Peter D Kwong
Structure of a V3-containing HIV-1 gp120 core.
Science (New York, N.Y.) 2005;310(5750):1025-8.
2005: Claudia C Mische; Hassan Javanbakht; Byeongwoon Song; Felipe Diaz-Griffero; Matthew Stremlau; Bettina Strack; Zhihai Si; Joseph Sodroski
Retroviral restriction factor TRIM5alpha is a trimer.
Journal of virology 2005;79(22):14446-50.
2005: Shaomin Tian; Won-Tak Choi; Dongxiang Liu; James Pesavento; Youli Wang; Jing An; Joseph Sodroski; Ziwei Huang
Distinct functional sites for human immunodeficiency virus type 1 and stromal cell-derived factor 1alpha on CXCR4 transmembrane helical domains.
Journal of virology 2005;79(20):12667-73.
2005: Xinzhen Yang; Svetla Kurteva; Xinping Ren; Sandra Lee; Joseph Sodroski
Stoichiometry of envelope glycoprotein trimers in the entry of human immunodeficiency virus type 1.
Journal of virology 2005;79(19):12132-47.
2005: Markus Koch; James Frazier; Joseph Sodroski; Richard Wyatt
Characterization of antibody responses to purified HIV-1 gp120 glycoproteins fused with the molecular adjuvant C3d.
Virology 2005;340(2):277-84.
2005: Marie Pancera; Jacob Lebowitz; Arne Schön; Ping Zhu; Ernesto Freire; Peter D Kwong; Kenneth H Roux; Joseph Sodroski; Richard Wyatt
Soluble mimetics of human immunodeficiency virus type 1 viral spikes produced by replacement of the native trimerization domain with a heterologous trimerization motif: characterization and ligand binding analysis.
Journal of virology 2005;79(15):9954-69.
2005: Hassan Javanbakht; Felipe Diaz-Griffero; Matthew Stremlau; Zhihai Si; Joseph Sodroski
The contribution of RING and B-box 2 domains to retroviral restriction mediated by monkey TRIM5alpha.
The Journal of biological chemistry 2005;280(29):26933-40.
2005: Claudia C Mische; Wen Yuan; Bettina Strack; Stewart Craig; Michael Farzan; Joseph Sodroski
An alternative conformation of the gp41 heptad repeat 1 region coiled coil exists in the human immunodeficiency virus (HIV-1) envelope glycoprotein precursor.
Virology 2005;338(1):133-43.
2005: Carolina Herrera; Per Johan Klasse; Elizabeth Michael; Shivani Kake; Kelly Barnes; Christopher W Kibler; Lila Campbell-Gardener; Zhihai Si; Joseph Sodroski; John P Moore; Simon Beddows
The impact of envelope glycoprotein cleavage on the antigenicity, infectivity, and neutralization sensitivity of Env-pseudotyped human immunodeficiency virus type 1 particles.
Virology 2005;338(1):154-72.
2005: Chih-chin Huang; François Stricher; Loic MARTIN; Julie M Decker; Shahzad Majeed; Philippe Barthe; Wayne A Hendrickson; James Robinson; Christian Roumestand; Joseph Sodroski; Richard Wyatt; George M Shaw; Claudio Vita; Peter D Kwong
Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth.
Structure (London, England : 1993) 2005;13(5):755-68.
2005: Byeongwoon Song; Bert Gold; Colm O'hUigin; Hassan Javanbakht; Xing Li; Matthew Stremlau; Cheryl A Winkler; Michael Dean; Joseph Sodroski
The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primates.
Journal of virology 2005;79(10):6111-21.
2005: Shi-Hua Xiang; Michael Farzan; Zhihai Si; Navid Madani; Liping Wang; Eric Rosenberg; James Robinson; Joseph Sodroski
Functional mimicry of a human immunodeficiency virus type 1 coreceptor by a neutralizing monoclonal antibody.
Journal of virology 2005;79(10):6068-77.
2005: Xinping Ren; Joseph Sodroski; Xinzhen Yang
An unrelated monoclonal antibody neutralizes human immunodeficiency virus type 1 by binding to an artificial epitope engineered in a functionally neutral region of the viral envelope glycoproteins.
Journal of virology 2005;79(9):5616-24.
2005: Iva Navratilova; Joseph Sodroski; David G Myszka
Solubilization, stabilization, and purification of chemokine receptors using biosensor technology.
Analytical biochemistry 2005;339(2):271-81.
2005: Byeongwoon Song; Hassan Javanbakht; Michel Perron; Do Hyun Park; Matthew Stremlau; Joseph Sodroski
Retrovirus restriction by TRIM5alpha variants from Old World and New World primates.
Journal of virology 2005;79(7):3930-7.
2005: Xinzhen Yang; Svetla Kurteva; Sandra Lee; Joseph Sodroski
Stoichiometry of antibody neutralization of human immunodeficiency virus type 1.
Journal of virology 2005;79(6):3500-8.
2005: Matthew Stremlau; Michel Perron; Sohanya Welikala; Joseph Sodroski
Species-specific variation in the B30.2(SPRY) domain of TRIM5alpha determines the potency of human immunodeficiency virus restriction.
Journal of virology 2005;79(5):3139-45.
2005: Wen Yuan; Stewart Craig; Xinzhen Yang; Joseph Sodroski
Inter-subunit disulfide bonds in soluble HIV-1 envelope glycoprotein trimers.
Virology 2005;332(1):369-83.
2005: Christoph Grundner; Yuxing Li; Mark K Louder; John R Mascola; Xinzhen Yang; Joseph Sodroski; Richard Wyatt
Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins.
Virology 2005;331(1):33-46.
2004: Christoph Grundner; Marie Pancera; Joung-Mo Kang; Markus Koch; Joseph Sodroski; Richard Wyatt
Factors limiting the immunogenicity of HIV-1 gp120 envelope glycoproteins.
Virology 2004;330(1):233-48.
2004: Fred W Peyerl; Heidi S Bazick; Michael H Newberg; Dan H Barouch; Joseph Sodroski; Norman L Letvin
Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope.
Journal of virology 2004;78(24):13901-10.
2004: Xinzhen Yang; Vesko Tomov; Svetla Kurteva; Liping Wang; Xinping Ren; Miroslaw K Gorny; Susan Zolla-Pazner; Joseph Sodroski
Characterization of the outer domain of the gp120 glycoprotein from human immunodeficiency virus type 1.
Journal of virology 2004;78(23):12975-86.
2004: Michel Perron; Matthew Stremlau; Byeongwoon Song; Wes Ulm; Richard C Mulligan; Joseph Sodroski
TRIM5alpha mediates the postentry block to N-tropic murine leukemia viruses in human cells.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(32):11827-32.
2004: Jianbin Wang; Gregory J Babcock; Hyeryun Choe; Michael Farzan; Joseph Sodroski; Dana Gabuzda
N-linked glycosylation in the CXCR4 N-terminus inhibits binding to HIV-1 envelope glycoproteins.
Virology 2004;324(1):140-50.
2004: Wen Yuan; Stewart Craig; Zhihai Si; Michael Farzan; Joseph Sodroski
CD4-induced T-20 binding to human immunodeficiency virus type 1 gp120 blocks interaction with the CXCR4 coreceptor.
Journal of virology 2004;78(10):5448-57.
2004: Christopher M Owens; Byeongwoon Song; Michel Perron; Peter C Yang; Matthew Stremlau; Joseph Sodroski
Binding and susceptibility to postentry restriction factors in monkey cells are specified by distinct regions of the human immunodeficiency virus type 1 capsid.
Journal of virology 2004;78(10):5423-37.
2004: Joseph F Bower; Xinzhen Yang; Joseph Sodroski; Ted M Ross
Elicitation of neutralizing antibodies with DNA vaccines expressing soluble stabilized human immunodeficiency virus type 1 envelope glycoprotein trimers conjugated to C3d.
Journal of virology 2004;78(9):4710-9.
2004: Byeongwoon Song; Mark Cayabyab; Ngoc Phan; Liping Wang; Michael K Axthelm; Norman L Letvin; Joseph Sodroski
Neutralization sensitivity of a simian-human immunodeficiency virus (SHIV-HXBc2P 3.2N) isolated from an infected rhesus macaque with neurological disease.
Virology 2004;322(1):168-81.
2004: Zhihai Si; Navid Madani; Jason M. Cox; Jason J Chruma; Jeffrey C Klein; Arne Schön; Ngoc Phan; Liping Wang; Alyssa C Biorn; Simon Cocklin; Irwin Chaiken; Ernesto Freire; Amos B Smith; Joseph Sodroski
Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(14):5036-41.
2004: Navid Madani; Ana Luisa Perdigoto; Kumar Srinivasan; Jason M. Cox; Jason J Chruma; Judith LaLonde; Martha Head; Amos B Smith; Joseph Sodroski
Localized changes in the gp120 envelope glycoprotein confer resistance to human immunodeficiency virus entry inhibitors BMS-806 and #155.
Journal of virology 2004;78(7):3742-52.
2004: Chih-chin Huang; Miro Venturi; Shahzad Majeed; Michael J Moore; Sanjay Phogat; Mei-Yun Zhang; Dimiter S Dimitrov; Wayne A Hendrickson; James Robinson; Joseph Sodroski; Richard Wyatt; Hyeryun Choe; Michael Farzan; Peter D Kwong
Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(9):2706-11.
2004: Dennis R Burton; Ronald C Desrosiers; Robert W Doms; Wayne C Koff; Peter D Kwong; John P Moore; Gary Nabel; Joseph Sodroski; Ian A Wilson; Richard Wyatt
HIV vaccine design and the neutralizing antibody problem.
Nature immunology 2004;5(3):233-6.
2004: Matthew Stremlau; Christopher M Owens; Michel Perron; Michael Kiessling; Patrick Autissier; Joseph Sodroski
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys.
Nature 2004;427(6977):848-53.
2004: Alyssa C Biorn; Simon Cocklin; Navid Madani; Zhihai Si; Tijana Ivanovic; James Samanen; Donald Van Ryk; Ralph Pantophlet; Dennis R Burton; Ernesto Freire; Joseph Sodroski; Irwin Chaiken
Mode of action for linear peptide inhibitors of HIV-1 gp120 interactions.
Biochemistry 2004;43(7):1928-38.
2004: Zhihai Si; Paul R Gorry; Greg Babcock; Christopher M Owens; Mark Cayabyab; Ngoc Phan; Joseph Sodroski
Envelope glycoprotein determinants of increased entry in a pathogenic simian-human immunodeficiency virus (SHIV-HXBc2P 3.2) passaged in monkeys.
AIDS research and human retroviruses 2004;20(2):163-73.
2004: Joseph Sodroski
Innate intracellular immunity to retroviruses.
Harvey lectures 2004;100():143-53.
2004: Mark Cayabyab; Daniela Rohne; Georgios Pollakis; Claudia Mische; Tsehaynesh Messele; Almaz Abebe; Bijan Etemad-Moghadam; Peter Yang; Scott Henson; Michael K Axthelm; Jaap Goudsmit; Norman L Letvin; Joseph Sodroski
Rapid CD4+ T-lymphocyte depletion in rhesus monkeys infected with a simian-human immunodeficiency virus expressing the envelope glycoproteins of a primary dual-tropic Ethiopian Clade C HIV type 1 isolate.
AIDS research and human retroviruses 2004;20(1):27-40.
2004: Richard Lu; Noriko Nakajima; Wolfgang Hofmann; Monsef Benkirane; Kuan-Teh Jeang; Joseph Sodroski; Alan Engelman; Kuan Teh-Jeang
Simian virus 40-based replication of catalytically inactive human immunodeficiency virus type 1 integrase mutants in nonpermissive T cells and monocyte-derived macrophages.
Journal of virology 2004;78(2):658-68.
2003: Shi-Hua Xiang; Liping Wang; Mariam Abreu; Chih-Chin Huang; Peter D Kwong; Eric Rosenberg; James E Robinson; Joseph Sodroski
Epitope mapping and characterization of a novel CD4-induced human monoclonal antibody capable of neutralizing primary HIV-1 strains.
Virology 2003;315(1):124-34.
2003: Aran F Labrijn; Pascal Poignard; Aarti Raja; Michael B Zwick; Karla Delgado; Michael Franti; James M Binley; Veronique Vivona; Christoph Grundner; Chih-Chin Huang; Miro Venturi; Christos J Petropoulos; Terri Wrin; Dimiter S Dimitrov; James Robinson; Peter D Kwong; Richard Wyatt; Joseph Sodroski; Dennis R Burton
Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1.
Journal of virology 2003;77(19):10557-65.
2003: Markus Koch; Marie Pancera; Peter D Kwong; Peter Kolchinsky; Christoph Grundner; Liping Wang; Wayne A Hendrickson; Joseph Sodroski; Richard Wyatt
Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition.
Virology 2003;313(2):387-400.
2003: Xinzhen Yang; Erin Mahony; Geoffrey Holm; Aemro Kassa; Joseph Sodroski
Role of the gp120 inner domain beta-sandwich in the interaction between the human immunodeficiency virus envelope glycoprotein subunits.
Virology 2003;313(1):117-25.
2003: Hyeryun Choe; Wenhui Li; Paulette L Wright; Natalya Vasilieva; Miro Venturi; Chih-Chin Huang; Christoph Grundner; Tatyana Dorfman; Michael B Zwick; Liping Wang; Eric S Rosenberg; Peter D Kwong; Dennis R Burton; James E Robinson; Joseph Sodroski; Michael Farzan
Tyrosine sulfation of human antibodies contributes to recognition of the CCR5 binding region of HIV-1 gp120.
Cell 2003;114(2):161-70.
2003: Jason A LaBonte; Navid Madani; Joseph Sodroski
Cytolysis by CCR5-using human immunodeficiency virus type 1 envelope glycoproteins is dependent on membrane fusion and can be inhibited by high levels of CD4 expression.
Journal of virology 2003;77(12):6645-59.
2003: Peter Stenlund; Gregory J Babcock; Joseph Sodroski; David G Myszka
Capture and reconstitution of G protein-coupled receptors on a biosensor surface.
Analytical biochemistry 2003;316(2):243-50.
2003: Lisa A Cavacini; Mark Duval; Leslie Song; Rebecca Sangster; Shi-Hua Xiang; Joseph Sodroski; Marshall R Posner
Conformational changes in env oligomer induced by an antibody dependent on the V3 loop base.
AIDS (London, England) 2003;17(5):685-9.
2003: Zhihai Si; Ngoc Phan; Enko Kiprilov; Joseph Sodroski
Effects of HIV type 1 envelope glycoprotein proteolytic processing on antigenicity.
AIDS research and human retroviruses 2003;19(3):217-26.
2003: Gregory J Babcock; Michael Farzan; Joseph Sodroski
Ligand-independent dimerization of CXCR4, a principal HIV-1 coreceptor.
The Journal of biological chemistry 2003;278(5):3378-85.
2003: Christopher M Owens; Peter C Yang; Heinrich G Göttlinger; Joseph Sodroski
Human and simian immunodeficiency virus capsid proteins are major viral determinants of early, postentry replication blocks in simian cells.
Journal of virology 2003;77(1):726-31.
2003: Aarti Raja; Miro Venturi; Peter D Kwong; Joseph Sodroski
CD4 binding site antibodies inhibit human immunodeficiency virus gp120 envelope glycoprotein interaction with CCR5.
Journal of virology 2003;77(1):713-8.
2002: Peter D Kwong; Michael Doyle; David J Casper; Claudia Cicala; Stephanie A Leavitt; Shahzad Majeed; Tavis D Steenbeke; Miro Venturi; Irwin Chaiken; Michael Fung; Hermann Katinger; Paul W I H Parren; James Robinson; Donald Van Ryk; Liping Wang; Dennis R Burton; Ernesto Freire; Richard Wyatt; Joseph Sodroski; Wayne A Hendrickson; James Arthos
HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites.
Nature 2002;420(6916):678-82.
2002: Shi-Hua Xiang; Najah Doka; Rabeéa K Choudhary; Joseph Sodroski; James E Robinson
Characterization of CD4-induced epitopes on the HIV type 1 gp120 envelope glycoprotein recognized by neutralizing human monoclonal antibodies.
AIDS research and human retroviruses 2002;18(16):1207-17.
2002: Stéphane Basmaciogullari; Gregory J Babcock; Donald Van Ryk; Woj M Wojtowicz; Joseph Sodroski
Identification of conserved and variable structures in the human immunodeficiency virus gp120 glycoprotein of importance for CXCR4 binding.
Journal of virology 2002;76(21):10791-800.
2002: Michael Farzan; Susan Chung; Wenhui Li; Natalya Vasilieva; Paulette L Wright; Christine E Schnitzler; Robb J Marchione; Craig Gerard; Norma P Gerard; Joseph Sodroski; Hyeryun Choe
Tyrosine-sulfated peptides functionally reconstitute a CCR5 variant lacking a critical amino-terminal region.
The Journal of biological chemistry 2002;277(43):40397-402.
2002: Shi-Hua Xiang; Peter D Kwong; Rishi Gupta; Carlo D Rizzuto; David J Casper; Richard Wyatt; Liping Wang; Wayne A Hendrickson; Michael Doyle; Joseph Sodroski
Mutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoprotein.
Journal of virology 2002;76(19):9888-99.
2002: Woj M Wojtowicz; Michael Farzan; John L Joyal; Kara Carter; Gregory J Babcock; David I Israel; Joseph Sodroski; Tajib Mirzabekov
Stimulation of enveloped virus infection by beta-amyloid fibrils.
The Journal of biological chemistry 2002;277(38):35019-24.
2002: Jason A LaBonte; Gregory J Babcock; Trushar Patel; Joseph Sodroski
Blockade of HIV-1 infection of New World monkey cells occurs primarily at the stage of virus entry.
The Journal of experimental medicine 2002;196(4):431-45.
2002: Cynthia S Dowd; Stephanie A Leavitt; Gregory Babcock; Alexis P Godillot; Donald Van Ryk; Gabriela Canziani; Joseph Sodroski; Ernesto Freire; Irwin Chaiken
Beta-turn Phe in HIV-1 Env binding site of CD4 and CD4 mimetic miniprotein enhances Env binding affinity but is not required for activation of co-receptor/17b site.
Biochemistry 2002;41(22):7038-46.
2002: Naiming Zhou; Zhaowen Luo; Jiansong Luo; Xuejun Fan; Mark Cayabyab; Megumi Hiraoka; Dongxiang Liu; Xiaobing Han; James Pesavento; Chang-Zhi Dong; Youli Wang; Jing An; Hideko Kaji; Joseph Sodroski; Ziwei Huang
Exploring the stereochemistry of CXCR4-peptide recognition and inhibiting HIV-1 entry with D-peptides derived from chemokines.
The Journal of biological chemistry 2002;277(20):17476-85.
2002: Bijan Etemad-Moghadam; Daniela Rhone; Tavis Steenbeke; Ying Sun; Judith Manola; Rebecca Gelman; John W Fanton; Paul Racz; Klara Tenner-Racz; Michael K Axthelm; Norman L Letvin; Joseph Sodroski
Understanding the basis of CD4(+) T-cell depletion in macaques infected by a simian-human immunodeficiency virus.
Vaccine 2002;20(15):1934-7.
2002: Xinzhen Yang; Juliette Lee; Erin M Mahony; Peter D Kwong; Richard Wyatt; Joseph Sodroski
Highly stable trimers formed by human immunodeficiency virus type 1 envelope glycoproteins fused with the trimeric motif of T4 bacteriophage fibritin.
Journal of virology 2002;76(9):4634-42.
2002: Christoph Grundner; Tajib Mirzabekov; Joseph Sodroski; Richard Wyatt
Solid-phase proteoliposomes containing human immunodeficiency virus envelope glycoproteins.
Journal of virology 2002;76(7):3511-21.
2001: N Bannert; Stewart Craig; Michael Farzan; D Sogah; N V Santo; Hyeryun Choe; Joseph Sodroski
Sialylated O-glycans and sulfated tyrosines in the NH2-terminal domain of CC chemokine receptor 5 contribute to high affinity binding of chemokines.
The Journal of experimental medicine 2001;194(11):1661-73.
2001: N Bannert; Michael Farzan; D S Friend; H Ochi; Kursteen S Price; Joseph Sodroski; Joshua A Boyce
Human Mast cell progenitors can be infected by macrophagetropic human immunodeficiency virus type 1 and retain virus with maturation in vitro.
Journal of virology 2001;75(22):10808-14.
2001: Gregory J Babcock; Tajib Mirzabekov; Woj M Wojtowicz; Joseph Sodroski
Ligand binding characteristics of CXCR4 incorporated into paramagnetic proteoliposomes.
The Journal of biological chemistry 2001;276(42):38433-40.
2001: Bijan Etemad-Moghadam; D Rhone; Tavis Steenbeke; Ying Sun; Judith Manola; Rebecca Gelman; John W Fanton; Paul Racz; Klara Tenner-Racz; Michael K Axthelm; Norman L Letvin; Joseph Sodroski
Membrane-fusing capacity of the human immunodeficiency virus envelope proteins determines the efficiency of CD+ T-cell depletion in macaques infected by a simian-human immunodeficiency virus.
Journal of virology 2001;75(12):5646-55.
2001: Zhihai Si; Mark Cayabyab; Joseph Sodroski
Envelope glycoprotein determinants of neutralization resistance in a simian-human immunodeficiency virus (SHIV-HXBc2P 3.2) derived by passage in monkeys.
Journal of virology 2001;75(9):4208-18.
2001: Peter Kolchinsky; Enko Kiprilov; P Bartley; R Rubinstein; Joseph Sodroski
Loss of a single N-linked glycan allows CD4-independent human immunodeficiency virus type 1 infection by altering the position of the gp120 V1/V2 variable loops.
Journal of virology 2001;75(7):3435-43.
2001: Peter Kolchinsky; Enko Kiprilov; Joseph Sodroski
Increased neutralization sensitivity of CD4-independent human immunodeficiency virus variants.
Journal of virology 2001;75(5):2041-50.
2001: Wei Zhang; Alexis P Godillot; Richard Wyatt; Joseph Sodroski; Irwin Chaiken
Antibody 17b binding at the coreceptor site weakens the kinetics of the interaction of envelope glycoprotein gp120 with CD4.
Biochemistry 2001;40(6):1662-70.
2001: X Yang; Richard Wyatt; Joseph Sodroski
Improved elicitation of neutralizing antibodies against primary human immunodeficiency viruses by soluble stabilized envelope glycoprotein trimers.
Journal of virology 2001;75(3):1165-71.
2000: Peter D Kwong; Richard Wyatt; Shahzad Majeed; James Robinson; Raymond W Sweet; Joseph Sodroski; Wayne A Hendrickson
Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Structure (London, England : 1993) 2000;8(12):1329-39.
2000: Mark Cayabyab; Shuji Hinuma; Michael Farzan; Hyeryun Choe; Shoji Fukusumi; C Kitada; N Nishizawa; M Hosoya; O Nishimura; Tsehaynesh Messele; Georgios Pollakis; Jaap Goudsmit; M Fujino; Joseph Sodroski
Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry.
Journal of virology 2000;74(24):11972-6.
2000: Y Ye; Z H Si; John P Moore; Joseph Sodroski
Association of structural changes in the V2 and V3 loops of the gp120 envelope glycoprotein with acquisition of neutralization resistance in a simian-human immunodeficiency virus passaged in vivo.
Journal of virology 2000;74(24):11955-62.
2000: N Bannert; D Schenten; Stewart Craig; Joseph Sodroski
The level of CD4 expression limits infection of primary rhesus monkey macrophages by a T-tropic simian immunodeficiency virus and macrophagetropic human immunodeficiency viruses.
Journal of virology 2000;74(23):10984-93.
2000: Jason A LaBonte; T Patel; Wolfgang Hofmann; Joseph Sodroski
Importance of membrane fusion mediated by human immunodeficiency virus envelope glycoproteins for lysis of primary CD4-positive T cells.
Journal of virology 2000;74(22):10690-8.
2000: Michael Farzan; Natalya Vasilieva; Christine E Schnitzler; S Chung; James Robinson; Norma P Gerard; Craig Gerard; Hyeryun Choe; Joseph Sodroski
A tyrosine-sulfated peptide based on the N terminus of CCR5 interacts with a CD4-enhanced epitope of the HIV-1 gp120 envelope glycoprotein and inhibits HIV-1 entry.
The Journal of biological chemistry 2000;275(43):33516-21.
2000: David G Myszka; Raymond W Sweet; Preston Hensley; Michael Brigham-Burke; Peter D Kwong; Wayne A Hendrickson; Richard Wyatt; Joseph Sodroski; Michael Doyle
Energetics of the HIV gp120-CD4 binding reaction.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(16):9026-31.
2000: Tajib Mirzabekov; H Kontos; Michael Farzan; Wayne A Marasco; Joseph Sodroski
Paramagnetic proteoliposomes containing a pure, native, and oriented seven-transmembrane segment protein, CCR5.
Nature biotechnology 2000;18(6):649-54.
2000: Xinzhen Yang; Michael Farzan; Richard Wyatt; Joseph Sodroski
Characterization of stable, soluble trimers containing complete ectodomains of human immunodeficiency virus type 1 envelope glycoproteins.
Journal of virology 2000;74(12):5716-25.
2000: Carlo D Rizzuto; Joseph Sodroski
Fine definition of a conserved CCR5-binding region on the human immunodeficiency virus type 1 glycoprotein 120.
AIDS research and human retroviruses 2000;16(8):741-9.
2000: Xinzhen Yang; L Florin; Michael Farzan; Peter Kolchinsky; Peter D Kwong; Joseph Sodroski; Richard Wyatt
Modifications that stabilize human immunodeficiency virus envelope glycoprotein trimers in solution.
Journal of virology 2000;74(10):4746-54.
2000: Bijan Etemad-Moghadam; Ying Sun; E K Nicholson; M Fernandes; K Liou; R Gomila; Juliette Lee; Joseph Sodroski
Envelope glycoprotein determinants of increased fusogenicity in a pathogenic simian-human immunodeficiency virus (SHIV-KB9) passaged in vivo.
Journal of virology 2000;74(9):4433-40.
2000: Björn R Gundlach; M G Lewis; Sieghart Sopper; T Schnell; Joseph Sodroski; Christiane Stahl-Hennig; Klaus Uberla
Evidence for recombination of live, attenuated immunodeficiency virus vaccine with challenge virus to a more virulent strain.
Journal of virology 2000;74(8):3537-42.
2000: Peter D Kwong; Richard Wyatt; Quentin J Sattentau; Joseph Sodroski; Wayne A Hendrickson
Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus.
Journal of virology 2000;74(4):1961-72.
2000: Maxime Moulard; Hugues Lortat-Jacob; I Mondor; G Roca; Richard Wyatt; Joseph Sodroski; L Zhao; W Olson; Peter D Kwong; Quentin J Sattentau
Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120.
Journal of virology 2000;74(4):1948-60.
2000: Hua-Xin Liao; B Etemad-Moghadam; David C Montefiori; Y Sun; Joseph Sodroski; Richard M Scearce; Robert W Doms; James R Thomasch; S Robinson; Norman L Letvin; Barton F Haynes
Induction of antibodies in guinea pigs and rhesus monkeys against the human immunodeficiency virus type 1 envelope: neutralization of nonpathogenic and pathogenic primary isolate simian/human immunodeficiency virus strains.
Journal of virology 2000;74(1):254-63.
1999: J M Crawford; Patricia L Earl; Bernard Moss; Keith A Reimann; Michael S Wyand; Kelledy Manson; Miroslawa Bilska; J T Zhou; C. David Pauza; P W Parren; D R Burton; Joseph Sodroski; Norman L Letvin; David C Montefiori
Characterization of primary isolate-like variants of simian-human immunodeficiency virus.
Journal of virology 1999;73(12):10199-207.
1999: W Hofmann; David Schubert; J LaBonte; L Munson; S Gibson; J Scammell; P Ferrigno; Joseph Sodroski
Species-specific, postentry barriers to primate immunodeficiency virus infection.
Journal of virology 1999;73(12):10020-8.
1999: Joseph Sodroski
HIV-1 entry inhibitors in the side pocket.
Cell 1999;99(3):243-6.
1999: Tajib Mirzabekov; N Bannert; Michael Farzan; Wolfgang Hofmann; Peter Kolchinsky; Lizi Wu; Richard Wyatt; Joseph Sodroski
Enhanced expression, native purification, and characterization of CCR5, a principal HIV-1 coreceptor.
The Journal of biological chemistry 1999;274(40):28745-50.
1999: Bijan Etemad-Moghadam; Ying Sun; E K Nicholson; GB Karlsson; D Schenten; Joseph Sodroski
Determinants of neutralization resistance in the envelope glycoproteins of a simian-human immunodeficiency virus passaged in vivo.
Journal of virology 1999;73(10):8873-9.
1999: Peter Kolchinsky; Tajib Mirzabekov; Michael Farzan; Enko Kiprilov; Mark Cayabyab; L J Mooney; Hyeryun Choe; Joseph Sodroski
Adaptation of a CCR5-using, primary human immunodeficiency virus type 1 isolate for CD4-independent replication.
Journal of virology 1999;73(10):8120-6.
1999: Wei Zhang; Gabriela Canziani; Carmela G Plugariu; Richard Wyatt; Joseph Sodroski; R Sweet; Peter D Kwong; Wayne A Hendrickson; Irwin Chaiken
Conformational changes of gp120 in epitopes near the CCR5 binding site are induced by CD4 and a CD4 miniprotein mimetic.
Biochemistry 1999;38(29):9405-16.
1999: D Schenten; L Marcon; GB Karlsson; C Parolin; T Kodama; Norma P Gerard; Joseph Sodroski
Effects of soluble CD4 on simian immunodeficiency virus infection of CD4-positive and CD4-negative cells.
Journal of virology 1999;73(7):5373-80.
1999: Michael Farzan; Tajib Mirzabekov; Peter Kolchinsky; Richard Wyatt; Mark Cayabyab; Norma P Gerard; Craig Gerard; Joseph Sodroski; Hyeryun Choe
Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry.
Cell 1999;96(5):667-76.
1999: Peter D Kwong; Richard Wyatt; E Desjardins; James Robinson; J S Culp; B D Hellmig; Raymond W Sweet; Joseph Sodroski; Wayne A Hendrickson
Probability analysis of variational crystallization and its application to gp120, the exterior envelope glycoprotein of type 1 human immunodeficiency virus (HIV-1).
The Journal of biological chemistry 1999;274(7):4115-23.
1999: Mark Cayabyab; GB Karlsson; Bijan Etemad-Moghadam; W Hofmann; Tavis Steenbeke; M Halloran; John W Fanton; Michael K Axthelm; Norman L Letvin; Joseph Sodroski
Changes in human immunodeficiency virus type 1 envelope glycoproteins responsible for the pathogenicity of a multiply passaged simian-human immunodeficiency virus (SHIV-HXBc2).
Journal of virology 1999;73(2):976-84.
1999: H Shen; Tao Cheng; Frederic Preffer; David Dombkowski; Michael H Tomasson; David E Golan; Otto O Yang; W Hofmann; Joseph Sodroski; Andrew D Luster; David T Scadden
Intrinsic human immunodeficiency virus type 1 resistance of hematopoietic stem cells despite coreceptor expression.
Journal of virology 1999;73(1):728-37.
1998: N Ruffing; N Sullivan; L Sharmeen; Joseph Sodroski; Lijun Wu
CCR5 has an expanded ligand-binding repertoire and is the primary receptor used by MCP-2 on activated T cells.
Cellular immunology 1998;189(2):160-8.
1998: L Huang; Irene Bosch; W Hofmann; Joseph Sodroski; Arthur B Pardee
Tat protein induces human immunodeficiency virus type 1 (HIV-1) coreceptors and promotes infection with both macrophage-tropic and T-lymphotropic HIV-1 strains.
Journal of virology 1998;72(11):8952-60.
1998: Bijan Etemad-Moghadam; GB Karlsson; M Halloran; Ying Sun; D Schenten; M Fernandes; Norman L Letvin; Joseph Sodroski
Characterization of simian-human immunodeficiency virus envelope glycoprotein epitopes recognized by neutralizing antibodies from infected monkeys.
Journal of virology 1998;72(10):8437-45.
1998: GB Karlsson; M Halloran; D Schenten; Juliette Lee; Paul Racz; Klara Tenner-Racz; Judith Manola; Rebecca Gelman; Bijan Etemad-Moghadam; E Desjardins; Richard Wyatt; Norma P Gerard; L Marcon; David H Margolin; John W Fanton; Michael K Axthelm; Norman L Letvin; Joseph Sodroski
The envelope glycoprotein ectodomains determine the efficiency of CD4+ T lymphocyte depletion in simian-human immunodeficiency virus-infected macaques.
The Journal of experimental medicine 1998;188(6):1159-71.
1998: I Mondor; Maxime Moulard; S Ugolini; Per Johan Klasse; James A Hoxie; Ali Amara; Thierry Delaunay; Richard Wyatt; Joseph Sodroski; Quentin J Sattentau
Interactions among HIV gp120, CD4, and CXCR4: dependence on CD4 expression level, gp120 viral origin, conservation of the gp120 COOH- and NH2-termini and V1/V2 and V3 loops, and sensitivity to neutralizing antibodies.
Virology 1998;248(2):394-405.
1998: Michael Farzan; Hyeryun Choe; E Desjardins; YanPing Sun; J Kuhn; J Cao; D Archambault; Peter Kolchinsky; Markus Koch; Richard Wyatt; Joseph Sodroski
Stabilization of human immunodeficiency virus type 1 envelope glycoprotein trimers by disulfide bonds introduced into the gp41 glycoprotein ectodomain.
Journal of virology 1998;72(9):7620-5.
1998: N Sullivan; YanPing Sun; James M Binley; J Lee; C F Barbas; P W Parren; D R Burton; Joseph Sodroski
Determinants of human immunodeficiency virus type 1 envelope glycoprotein activation by soluble CD4 and monoclonal antibodies.
Journal of virology 1998;72(8):6332-8.
1998: Hyeryun Choe; Michael Farzan; M Konkel; K Martin; YanPing Sun; L Marcon; Mark Cayabyab; M Berman; Martin E Dorf; Norma P Gerard; Craig Gerard; Joseph Sodroski
The orphan seven-transmembrane receptor apj supports the entry of primary T-cell-line-tropic and dualtropic human immunodeficiency virus type 1.
Journal of virology 1998;72(7):6113-8.
1998: Carlo D Rizzuto; Richard Wyatt; N Hernández-Ramos; Ying Sun; Peter D Kwong; Wayne A Hendrickson; Joseph Sodroski
A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding.
Science (New York, N.Y.) 1998;280(5371):1949-53.
1998: Richard Wyatt; Joseph Sodroski
The HIV-1 envelope glycoproteins: fusogens, antigens, and immunogens.
Science (New York, N.Y.) 1998;280(5371):1884-8.
1998: Richard Wyatt; Peter D Kwong; E Desjardins; Raymond W Sweet; James Robinson; Wayne A Hendrickson; Joseph Sodroski
The antigenic structure of the HIV gp120 envelope glycoprotein.
Nature 1998;393(6686):705-11.
1998: Peter D Kwong; Richard Wyatt; James Robinson; Raymond W Sweet; Joseph Sodroski; Wayne A Hendrickson
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody.
Nature 1998;393(6686):648-59.
1998: Hyeryun Choe; KA Martin; Michael Farzan; Joseph Sodroski; Norma P Gerard; Craig Gerard
Structural interactions between chemokine receptors, gp120 Env and CD4.
Seminars in immunology 1998;10(3):249-57.
1998: N Sullivan; YanPing Sun; Quentin J Sattentau; M Thali; D Wu; Galina Denisova; Jonathan M Gershoni; J Robinson; J Moore; Joseph Sodroski
CD4-Induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: consequences for virus entry and neutralization.
Journal of virology 1998;72(6):4694-703.
1998: JL Zhang; H Choe; Bruce J Dezube; Michael Farzan; PL Sharma; X C Zhou; L B Chen; M Ono; Stephen D Gillies; Y Wu; Joseph Sodroski; Clyde S Crumpacker
The bis-azo compound FP-21399 inhibits HIV-1 replication by preventing viral entry.
Virology 1998;244(2):530-41.
1998: JH Richardson; W Hofmann; Joseph Sodroski; Wayne A Marasco
Intrabody-mediated knockout of the high-affinity IL-2 receptor in primary human T cells using a bicistronic lentivirus vector.
Gene therapy 1998;5(5):635-44.
1998: David C Montefiori; Keith A Reimann; Michael S Wyand; Kelledy Manson; M G Lewis; R G Collman; Joseph Sodroski; Dani P Bolognesi; Norman L Letvin
Neutralizing antibodies in sera from macaques infected with chimeric simian-human immunodeficiency virus containing the envelope glycoproteins of either a laboratory-adapted variant or a primary isolate of human immunodeficiency virus type 1.
Journal of virology 1998;72(4):3427-31.
1998: A Li; H Katinger; Marshall R Posner; Lisa A Cavacini; Susan Zolla-Pazner; M K Gorny; Joseph Sodroski; T C Chou; Timothy W Baba; Ruth Ruprecht
Synergistic neutralization of simian-human immunodeficiency virus SHIV-vpu+ by triple and quadruple combinations of human monoclonal antibodies and high-titer anti-human immunodeficiency virus type 1 immunoglobulins.
Journal of virology 1998;72(4):3235-40.
1998: James M Binley; Richard Wyatt; E Desjardins; Peter D Kwong; Wayne A Hendrickson; John P Moore; Joseph Sodroski
Analysis of the interaction of antibodies with a conserved enzymatically deglycosylated core of the HIV type 1 envelope glycoprotein 120.
AIDS research and human retroviruses 1998;14(3):191-8.
1998: Cristina Parolin; Alessandra Borsetti; Hyeryun Choe; Michael Farzan; Peter Kolchinsky; M Heesen; Qui Fu Ma; Craig Gerard; Giorgio Palú; Martin E Dorf; Timothy A Springer; Joseph Sodroski
Use of murine CXCR-4 as a second receptor by some T-cell-tropic human immunodeficiency viruses.
Journal of virology 1998;72(2):1652-6.
1998: Michael Farzan; Hyeryun Choe; L Vaca; K Martin; YanPing Sun; E Desjardins; N Ruffing; Lijun Wu; Richard Wyatt; Norma P Gerard; Craig Gerard; Joseph Sodroski
A tyrosine-rich region in the N terminus of CCR5 is important for human immunodeficiency virus type 1 entry and mediates an association between gp120 and CCR5.
Journal of virology 1998;72(2):1160-4.
1998: Shan Lu; Richard Wyatt; JF Richmond; Farah Mustafa; Shixia Wang; J Weng; David C Montefiori; Joseph Sodroski; Harriet L Robinson
Immunogenicity of DNA vaccines expressing human immunodeficiency virus type 1 envelope glycoprotein with and without deletions in the V1/2 and V3 regions.
AIDS research and human retroviruses 1998;14(2):151-5.
1998: Edward A Berger; R W Doms; E M Fenyö; B T Korber; Dan R Littman; J P Moore; Quentin J Sattentau; H Schuitemaker; Joseph Sodroski; R A Weiss
A new classification for HIV-1.
Nature 1998;391(6664):240.
1997: J Cao; N Sullivan; E Desjardin; Cristina Parolin; J Robinson; Richard Wyatt; Joseph Sodroski
Replication and neutralization of human immunodeficiency virus type 1 lacking the V1 and V2 variable loops of the gp120 envelope glycoprotein.
Journal of virology 1997;71(12):9808-12.
1997: Richard Wyatt; E Desjardin; U Olshevsky; C Nixon; James M Binley; V Olshevsky; Joseph Sodroski
Analysis of the interaction of the human immunodeficiency virus type 1 gp120 envelope glycoprotein with the gp41 transmembrane glycoprotein.
Journal of virology 1997;71(12):9722-31.
1997: KA Martin; Richard Wyatt; Michael Farzan; Hyeryun Choe; L Marcon; E Desjardins; James Robinson; Joseph Sodroski; Craig Gerard; Norma P Gerard
CD4-independent binding of SIV gp120 to rhesus CCR5.
Science (New York, N.Y.) 1997;278(5342):1470-3.
1997: David H Margolin; Keith A Reimann; Joseph Sodroski; GB Karlsson; Klara Tenner-Racz; Paul Racz; Norman L Letvin
Immunoglobulin V(H) usage during primary infection of rhesus monkeys with chimeric simian-human immunodeficiency viruses.
Journal of virology 1997;71(11):8582-91.
1997: JH Richardson; Thomas Waldmann; Joseph Sodroski; Wayne A Marasco
Inducible knockout of the interleukin-2 receptor alpha chain: expression of the high-affinity IL-2 receptor is not required for the in vitro growth of HTLV-I-transformed cell lines.
Virology 1997;237(2):209-16.
1997: Michael Farzan; Hyeryun Choe; K Martin; L Marcon; Wolfgang Hofmann; GB Karlsson; YanPing Sun; P Barrett; N Marchand; N Sullivan; Norma P Gerard; Craig Gerard; Joseph Sodroski
Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection.
The Journal of experimental medicine 1997;186(3):405-11.
1997: Carlo D Rizzuto; Joseph Sodroski
Contribution of virion ICAM-1 to human immunodeficiency virus infectivity and sensitivity to neutralization.
Journal of virology 1997;71(6):4847-51.
1997: GB Karlsson; M Halloran; J Li; I W Park; R Gomila; Keith A Reimann; Michael K Axthelm; S A Iliff; Norman L Letvin; Joseph Sodroski
Characterization of molecularly cloned simian-human immunodeficiency viruses causing rapid CD4+ lymphocyte depletion in rhesus monkeys.
Journal of virology 1997;71(6):4218-25.
1997: A Li; Timothy W Baba; Joseph Sodroski; Susan Zolla-Pazner; M K Gorny; J Robinson; Marshall R Posner; H Katinger; C F Barbas; D R Burton; T C Chou; Ruth Ruprecht
Synergistic neutralization of a chimeric SIV/HIV type 1 virus with combinations of human anti-HIV type 1 envelope monoclonal antibodies or hyperimmune globulins.
AIDS research and human retroviruses 1997;13(8):647-56.
1997: Lijun Wu; William A Paxton; N Kassam; N Ruffing; J B Rottman; N Sullivan; Hyeryun Choe; Joseph Sodroski; W Newman; RA Koup; CR Mackay
CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro.
The Journal of experimental medicine 1997;185(9):1681-91.
1997: L Marcon; Joseph Sodroski
High degree of sensitivity of the simian immunodeficiency virus (SIVmac) envelope glycoprotein subunit association to amino acid changes in the glycoprotein 41 ectodomain.
AIDS research and human retroviruses 1997;13(6):441-7.
1997: Henrik J Ditzel; Paul W H I Parren; James M Binley; Joseph Sodroski; John P Moore; Carlos F Barbas; Dennis R Burton
Mapping the protein surface of human immunodeficiency virus type 1 gp120 using human monoclonal antibodies from phage display libraries.
Journal of molecular biology 1997;267(3):684-95.
1997: Michael Farzan; Hyeryun Choe; KA Martin; YanPing Sun; M Sidelko; CR Mackay; Norma P Gerard; Joseph Sodroski; Craig Gerard
HIV-1 entry and macrophage inflammatory protein-1beta-mediated signaling are independent functions of the chemokine receptor CCR5.
The Journal of biological chemistry 1997;272(11):6854-7.
1997: L Marcon; Hyeryun Choe; KA Martin; Michael Farzan; Paul D Ponath; Lijun Wu; W Newman; Norma P Gerard; Craig Gerard; Joseph Sodroski
Utilization of C-C chemokine receptor 5 by the envelope glycoproteins of a pathogenic simian immunodeficiency virus, SIVmac239.
Journal of virology 1997;71(3):2522-7.
1997: J He; Y Chen; Michael Farzan; Hyeryun Choe; Asa Ohagen; Suzanne Gartner; Jorge Busciglio; Xinzhen Yang; Wolfgang Hofmann; W Newman; CR Mackay; Joseph Sodroski; Dana Gabuzda
CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia.
Nature 1997;385(6617):645-9.
1996: Lijun Wu; Norma P Gerard; Richard Wyatt; Hyeryun Choe; Cristina Parolin; N Ruffing; Alessandra Borsetti; Angelo A Cardoso; E Desjardin; W Newman; Craig Gerard; Joseph Sodroski
CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.
Nature 1996;384(6605):179-83.
1996: Joseph Sodroski
Perspective: research highlights at the Dana-Farber Cancer Institute Center for AIDS Research (CFAR).
AIDS research and human retroviruses 1996;12(16):1499-502.
1996: Keith A Reimann; J T Li; R Veazey; M Halloran; I W Park; GB Karlsson; Joseph Sodroski; Norman L Letvin
A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys.
Journal of virology 1996;70(10):6922-8.
1996: GB Karlsson; F Gao; J Robinson; B Hahn; Joseph Sodroski
Increased envelope spike density and stability are not required for the neutralization resistance of primary human immunodeficiency viruses.
Journal of virology 1996;70(9):6136-42.
1996: C C Bleul; Michael Farzan; Hyeryun Choe; Cristina Parolin; I Clark-Lewis; Joseph Sodroski; Timothy A Springer
The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry.
Nature 1996;382(6594):829-33.
1996: Cristina Parolin; B Taddeo; G Palú; Joseph Sodroski
Use of cis- and trans-acting viral regulatory sequences to improve expression of human immunodeficiency virus vectors in human lymphocytes.
Virology 1996;222(2):415-22.
1996: I W Park; E Kondo; L Bergeron; J Park; Joseph Sodroski
Effects of human immunodeficiency virus type 1 infection on programmed cell death in the presence or absence of Bcl-2.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1996;12(4):321-8.
1996: James M Binley; Henrik J Ditzel; Carlos F Barbas; N Sullivan; Joseph Sodroski; Paul W H I Parren; Dennis R Burton
Human antibody responses to HIV type 1 glycoprotein 41 cloned in phage display libraries suggest three major epitopes are recognized and give evidence for conserved antibody motifs in antigen binding.
AIDS research and human retroviruses 1996;12(10):911-24.
1996: Hyeryun Choe; Michael Farzan; YanPing Sun; N Sullivan; Barrett J Rollins; Paul D Ponath; Lijun Wu; CR Mackay; Greg La Rosa; W Newman; Norma P Gerard; Craig Gerard; Joseph Sodroski
The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates.
Cell 1996;85(7):1135-48.
1996: Y Lu; Maria Salvato; C. David Pauza; J Li; Joseph Sodroski; Kelledy Manson; Michael S Wyand; Norman L Letvin; S Jenkins; N Touzjian; C Chutkowski; N Kushner; M LeFaile; L G Payne; B Roberts
Utility of SHIV for testing HIV-1 vaccine candidates in macaques.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1996;12(2):99-106.
1996: Keith A Reimann; J T Li; G Voss; C Lekutis; Klara Tenner-Racz; Paul Racz; W Lin; D C Montefiori; D Lee-Parritz; Y Lu; R G Collman; Joseph Sodroski; Norman L Letvin
An env gene derived from a primary human immunodeficiency virus type 1 isolate confers high in vivo replicative capacity to a chimeric simian/human immunodeficiency virus in rhesus monkeys.
Journal of virology 1996;70(5):3198-206.
1996: Y Lu; P Brosio; M Lafaile; J Li; R G Collman; Joseph Sodroski; Christopher J Miller
Vaginal transmission of chimeric simian/human immunodeficiency viruses in rhesus macaques.
Journal of virology 1996;70(5):3045-50.
1996: H T Poteat; U Ramstedt; S Yoon; M Dardik; E Terwilliger; Joseph Sodroski
Cyclic AMP-mediated growth arrest is associated with increased expression of human T cell leukemia virus type I structural and transforming genes.
AIDS research and human retroviruses 1996;12(6):527-33.
1996: I W Park; Joseph Sodroski
Targeting a foreign protein into virion particles by fusion with the Vpx protein of simian immunodeficiency virus.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1996;11(4):341-50.
1996: J P Moore; Joseph Sodroski
Antibody cross-competition analysis of the human immunodeficiency virus type 1 gp120 exterior envelope glycoprotein.
Journal of virology 1996;70(3):1863-72.
1996: Feng Gao; S G Morrison; David L Robertson; C L Thornton; S Craig; G Karlsson; Joseph Sodroski; M Morgado; B Galvao-Castro; Hagen von Briesen; S Beddows; J Weber; Paul M Sharp; George M Shaw; Beatrice H Hahn
Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G. The WHO and NIAID Networks for HIV Isolation and Characterization.
Journal of virology 1996;70(3):1651-67.
1996: J Cao; I W Park; A Cooper; Joseph Sodroski
Molecular determinants of acute single-cell lysis by human immunodeficiency virus type 1.
Journal of virology 1996;70(3):1340-54.
1996: Alexandra Trkola; M Purtscher; Thomas Muster; C Ballaun; A Buchacher; N Sullivan; K Srinivasan; Joseph Sodroski; J P Moore; Hermann Katinger
Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1.
Journal of virology 1996;70(2):1100-8.
1996: Joseph Sodroski; Richard Wyatt; U Olshevsky; V Olshevsky; J Moore
Conformation of the HIV-1 gp 120 envelope glycoprotein.
Antibiotics and chemotherapy 1996;48():184-7.
1995: I W Park; Joseph Sodroski
Amino acid sequence requirements for the incorporation of the Vpx protein of simian immunodeficiency virus into virion particles.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1995;10(5):506-10.
1995: J T Li; M Halloran; Carol I Lord; A Watson; J Ranchalis; M Fung; N L Letvin; Joseph Sodroski
Persistent infection of macaques with simian-human immunodeficiency viruses.
Journal of virology 1995;69(11):7061-7.
1995: S O Bøe; Joseph Sodroski; D E Helland; Chris Farnet
DNA end-joining in extracts from human cells.
Biochemical and biophysical research communications 1995;215(3):987-93.
1995: Richard Wyatt; J Moore; MA Accola; E Desjardin; J Robinson; Joseph Sodroski
Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding.
Journal of virology 1995;69(9):5723-33.
1995: Norman L Letvin; J Li; M Halloran; Martin Cranage; Erling Rud; Joseph Sodroski
Prior infection with a nonpathogenic chimeric simian-human immunodeficiency virus does not efficiently protect macaques against challenge with simian immunodeficiency virus.
Journal of virology 1995;69(7):4569-71.
1995: N Sullivan; YanPing Sun; J Li; W Hofmann; Joseph Sodroski
Replicative function and neutralization sensitivity of envelope glycoproteins from primary and T-cell line-passaged human immunodeficiency virus type 1 isolates.
Journal of virology 1995;69(7):4413-22.
1995: Zheng W Chen; Z C Kou; C Lekutis; Ling Shen; Dejiang Zhou; M Halloran; J Li; Joseph Sodroski; D Lee-Parritz; Norman L Letvin
T cell receptor V beta repertoire in an acute infection of rhesus monkeys with simian immunodeficiency viruses and a chimeric simian-human immunodeficiency virus.
The Journal of experimental medicine 1995;182(1):21-31.
1995: Fabrizio Mammano; E Kondo; Joseph Sodroski; AA Bukovsky; Heinrich G Göttlinger
Rescue of human immunodeficiency virus type 1 matrix protein mutants by envelope glycoproteins with short cytoplasmic domains.
Journal of virology 1995;69(6):3824-30.
1995: C Parolin; Joseph Sodroski
A defective HIV-1 vector for gene transfer to human lymphocytes.
Journal of molecular medicine (Berlin, Germany) 1995;73(6):279-88.
1995: Hyeryun Choe; Joseph Sodroski
Adaptation of human immunodeficiency virus type 1 to cells expressing a binding-deficient CD4 mutant (lysine 46 to aspartic acid).
Journal of virology 1995;69(5):2801-10.
1995: G Voss; J Li; Kelledy Manson; Michael S Wyand; Joseph Sodroski; Norman L Letvin
Human immunodeficiency virus type 1 envelope glycoprotein-specific cytotoxic T lymphocytes in simian-human immunodeficiency virus-infected rhesus monkeys.
Virology 1995;208(2):770-5.
1995: J H Richardson; Joseph Sodroski; Thomas Waldmann; Wayne A Marasco
Phenotypic knockout of the high-affinity human interleukin 2 receptor by intracellular single-chain antibodies against the alpha subunit of the receptor.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3137-41.
1995: I W Park; Joseph Sodroski
Functional analysis of the vpx, vpr, and nef genes of simian immunodeficiency virus.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1995;8(4):335-44.
1995: Henrik J Ditzel; James M Binley; J P Moore; Joseph Sodroski; N Sullivan; L S Sawyer; R M Hendry; W P Yang; Carlos F Barbas; Dennis R Burton
Neutralizing recombinant human antibodies to a conformational V2- and CD4-binding site-sensitive epitope of HIV-1 gp120 isolated by using an epitope-masking procedure.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(2):893-906.
1995: D Brand; K Srinivasan; Joseph Sodroski
Determinants of human immunodeficiency virus type 1 entry in the CDR2 loop of the CD4 glycoprotein.
Journal of virology 1995;69(1):166-71.
1995: P Marschang; Joseph Sodroski; Reinhard Wurzner; Manfred P Dierich
Decay-accelerating factor (CD55) protects human immunodeficiency virus type 1 from inactivation by human complement.
European journal of immunology 1995;25(1):285-90.
1995: C Shotton; C Arnold; Q Sattentau; Joseph Sodroski; Jane A McKeating
Identification and characterization of monoclonal antibodies specific for polymorphic antigenic determinants within the V2 region of the human immunodeficiency virus type 1 envelope glycoprotein.
Journal of virology 1995;69(1):222-30.
1994: I W Park; K Myrick; Joseph Sodroski
Effects of vif mutations on cell-free infectivity and replication of simian immunodeficiency virus.
Journal of acquired immune deficiency syndromes 1994;7(12):1228-36.
1994: Miroslaw K Gorny; J P Moore; Anthony J Conley; S Karwowska; Joseph Sodroski; Constance Williams; Sherri Burda; L J Boots; Susan Zolla-Pazner
Human anti-V2 monoclonal antibody that neutralizes primary but not laboratory isolates of human immunodeficiency virus type 1.
Journal of virology 1994;68(12):8312-20.
1994: M Thali; AA Bukovsky; E Kondo; B Rosenwirth; Christopher T Walsh; Joseph Sodroski; Heinrich G Göttlinger
Functional association of cyclophilin A with HIV-1 virions.
Nature 1994;372(6504):363-5.
1994: J P Moore; R L Willey; George K Lewis; J Robinson; Joseph Sodroski
Immunological evidence for interactions between the first, second, and fifth conserved domains of the gp120 surface glycoprotein of human immunodeficiency virus type 1.
Journal of virology 1994;68(11):6836-47.
1994: J Bagley; P J Dillon; C Rosen; J Robinson; Joseph Sodroski; Wayne A Marasco
Structural characterization of broadly neutralizing human monoclonal antibodies against the CD4 binding site of HIV-1 gp120.
Molecular immunology 1994;31(15):1149-60.
1994: C Y Kang; Kandasamy Hariharan; P L Nara; Joseph Sodroski; J P Moore
Immunization with a soluble CD4-gp120 complex preferentially induces neutralizing anti-human immunodeficiency virus type 1 antibodies directed to conformation-dependent epitopes of gp120.
Journal of virology 1994;68(9):5854-62.
1994: P Roben; J P Moore; M Thali; Joseph Sodroski; Carlos F Barbas; Dennis R Burton
Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1.
Journal of virology 1994;68(8):4821-8.
1994: J Cao; Baldev S Vasir; Joseph Sodroski
Changes in the cytopathic effects of human immunodeficiency virus type 1 associated with a single amino acid alteration in the ectodomain of the gp41 transmembrane glycoprotein.
Journal of virology 1994;68(7):4662-8.
1994: Cristina Parolin; Tatyana Dorfman; G Palú; Heinrich G Göttlinger; Joseph Sodroski
Analysis in human immunodeficiency virus type 1 vectors of cis-acting sequences that affect gene transfer into human lymphocytes.
Journal of virology 1994;68(6):3888-95.
1994: L Marcon; Joseph Sodroski
gp120-independent fusion mediated by the human immunodeficiency virus type 1 gp41 envelope glycoprotein: a reassessment.
Journal of virology 1994;68(3):1977-82.
1994: M Thali; M Charles; C Furman; Lisa A Cavacini; Marshall R Posner; J Robinson; Joseph Sodroski
Resistance to neutralization by broadly reactive antibodies to the human immunodeficiency virus type 1 gp120 glycoprotein conferred by a gp41 amino acid change.
Journal of virology 1994;68(2):674-80.
1994: J P Moore; Quentin J Sattentau; Richard Wyatt; Joseph Sodroski
Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies.
Journal of virology 1994;68(1):469-84.
1993: J P Moore; H Yoshiyama; David D Ho; J E Robinson; Joseph Sodroski
Antigenic variation in gp120s from molecular clones of HIV-1 LAI.
AIDS research and human retroviruses 1993;9(12):1185-93.
1993: J P Moore; B A Jameson; Quentin J Sattentau; R Willey; Joseph Sodroski
Towards a structure of the HIV-1 envelope glycoprotein gp120: an immunochemical approach.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1993;342(1299):83-8.
1993: Richard Wyatt; N Sullivan; M Thali; H Repke; D Ho; J Robinson; Marshall R Posner; Joseph Sodroski
Functional and immunologic characterization of human immunodeficiency virus type 1 envelope glycoproteins containing deletions of the major variable regions.
Journal of virology 1993;67(8):4557-65.
1993: J Moore; Q Sattentau; B Jameson; Joseph Sodroski
Monoclonal antibodies to HIV-1 gp120: a request.
AIDS research and human retroviruses 1993;9(7):695.
1993: Martin Schutten; Aine McKnight; R C Huisman; M Thali; Jane A McKeating; Joseph Sodroski; J Goudsmit; A D Osterhaus
Further characterization of an antigenic site of HIV-1 gp120 recognized by virus neutralizing human monoclonal antibodies.
AIDS (London, England) 1993;7(7):919-23.
1993: M Thali; J P Moore; C Furman; M Charles; D D Ho; J Robinson; Joseph Sodroski
Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding.
Journal of virology 1993;67(7):3978-88.
1993: N Sullivan; M Thali; C Furman; D D Ho; Joseph Sodroski
Effect of amino acid changes in the V1/V2 region of the human immunodeficiency virus type 1 gp120 glycoprotein on subunit association, syncytium formation, and recognition by a neutralizing antibody.
Journal of virology 1993;67(6):3674-9.
1993: J Cao; L Bergeron; E Helseth; M Thali; H Repke; Joseph Sodroski
Effects of amino acid changes in the extracellular domain of the human immunodeficiency virus type 1 gp41 envelope glycoprotein.
Journal of virology 1993;67(5):2747-55.
1992: Richard Wyatt; M Thali; S Tilley; A Pinter; Marshall R Posner; D Ho; J Robinson; Joseph Sodroski
Relationship of the human immunodeficiency virus type 1 gp120 third variable loop to a component of the CD4 binding site in the fourth conserved region.
Journal of virology 1992;66(12):6997-7004.
1992: Dana Gabuzda; K Lawrence; E Langhoff; E Terwilliger; Tatyana Dorfman; W A Haseltine; Joseph Sodroski
Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes.
Journal of virology 1992;66(11):6489-95.
1992: L Bergeron; Joseph Sodroski
Dissociation of unintegrated viral DNA accumulation from single-cell lysis induced by human immunodeficiency virus type 1.
Journal of virology 1992;66(10):5777-87.
1992: Wayne A Marasco; J Bagley; C Zani; Marshall R Posner; Lisa A Cavacini; W A Haseltine; Joseph Sodroski
Characterization of the cDNA of a broadly reactive neutralizing human anti-gp120 monoclonal antibody.
The Journal of clinical investigation 1992;90(4):1467-78.
1992: Joseph Sodroski
The human T-cell leukemia virus (HTLV) transactivator (Tax) protein.
Biochimica et biophysica acta 1992;1114(1):19-29.
1992: M Thali; C Furman; E Helseth; H Repke; Joseph Sodroski
Lack of correlation between soluble CD4-induced shedding of the human immunodeficiency virus type 1 exterior envelope glycoprotein and subsequent membrane fusion events.
Journal of virology 1992;66(9):5516-24.
1992: Jane A McKeating; M Thali; C Furman; S Karwowska; Miroslaw K Gorny; J Cordell; Susan Zolla-Pazner; Joseph Sodroski; Robin A Weiss
Amino acid residues of the human immunodeficiency virus type I gp120 critical for the binding of rat and human neutralizing antibodies that block the gp120-sCD4 interaction.
Virology 1992;190(1):134-42.
1992: M Thali; C Furman; D D Ho; J Robinson; S Tilley; A Pinter; Joseph Sodroski
Discontinuous, conserved neutralization epitopes overlapping the CD4-binding region of human immunodeficiency virus type 1 gp120 envelope glycoprotein.
Journal of virology 1992;66(9):5635-41.
1992: H Repke; Dana Gabuzda; G Palù; Frank Emmrich; Joseph Sodroski
Effects of CD4 synthetic peptides on HIV type I envelope glycoprotein function.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(5):1809-16.
1992: Ralph Grassmann; Susanne Berchtold; I Radant; M Alt; Bernhard Fleckenstein; Joseph Sodroski; W A Haseltine; U Ramstedt
Role of human T-cell leukemia virus type 1 X region proteins in immortalization of primary human lymphocytes in culture.
Journal of virology 1992;66(7):4570-5.
1992: Dana Gabuzda; A Lever; E Terwilliger; Joseph Sodroski
Effects of deletions in the cytoplasmic domain on biological functions of human immunodeficiency virus type 1 envelope glycoproteins.
Journal of virology 1992;66(6):3306-15.
1992: L Bergeron; N Sullivan; Joseph Sodroski
Target cell-specific determinants of membrane fusion within the human immunodeficiency virus type 1 gp120 third variable region and gp41 amino terminus.
Journal of virology 1992;66(4):2389-97.
1992: C Lekutis; U Olshevsky; C Furman; M Thali; Joseph Sodroski
Contribution of disulfide bonds in the carboxyl terminus of the human immunodeficiency virus type I gp120 glycoprotein to CD4 binding.
Journal of acquired immune deficiency syndromes 1992;5(1):78-81.
1992: Hyeryun Choe; Joseph Sodroski
Contribution of charged amino acids in the CDR2 region of CD4 to HIV-1 gp120 binding.
Journal of acquired immune deficiency syndromes 1992;5(2):204-10.
1992: J Li; Carol I Lord; W Haseltine; Norman L Letvin; Joseph Sodroski
Infection of cynomolgus monkeys with a chimeric HIV-1/SIVmac virus that expresses the HIV-1 envelope glycoproteins.
Journal of acquired immune deficiency syndromes 1992;5(7):639-46.
1992: M Thali; C Furman; B Wahren; Marshall R Posner; D D Ho; J Robinson; Joseph Sodroski
Cooperativity of neutralizing antibodies directed against the V3 and CD4 binding regions of the human immunodeficiency virus gp120 envelope glycoprotein.
Journal of acquired immune deficiency syndromes 1992;5(6):591-9.
1991: M Thali; U Olshevsky; C Furman; Dana Gabuzda; Marshall R Posner; Joseph Sodroski
Characterization of a discontinuous human immunodeficiency virus type 1 gp120 epitope recognized by a broadly reactive neutralizing human monoclonal antibody.
Journal of virology 1991;65(11):6188-93.
1991: M Thali; U Olshevsky; C Furman; Dana Gabuzda; J Li; Joseph Sodroski
Effects of changes in gp120-CD4 binding affinity on human immunodeficiency virus type 1 envelope glycoprotein function and soluble CD4 sensitivity.
Journal of virology 1991;65(9):5007-12.
1991: Heinrich G Göttlinger; Tatyana Dorfman; Joseph Sodroski; W A Haseltine
Effect of mutations affecting the p6 gag protein on human immunodeficiency virus particle release.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3195-9.
1991: E Helseth; U Olshevsky; C Furman; Joseph Sodroski
Human immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoprotein.
Journal of virology 1991;65(4):2119-23.
1991: Y C Lu; N Touzjian; M Stenzel; Tatyana Dorfman; Joseph Sodroski; W A Haseltine
The NF kappa B independent cis-acting sequences in HIV-1 LTR responsive to T-cell activation.
Journal of acquired immune deficiency syndromes 1991;4(2):173-7.
1991: M Poznansky; A Lever; L Bergeron; W Haseltine; Joseph Sodroski
Gene transfer into human lymphocytes by a defective human immunodeficiency virus type 1 vector.
Journal of virology 1991;65(1):532-6.
1991: Dana Gabuzda; U Olshevsky; P Bertani; W A Haseltine; Joseph Sodroski
Identification of membrane anchorage domains of the HIV-1 gp160 envelope glycoprotein precursor.
Journal of acquired immune deficiency syndromes 1991;4(1):34-40.
1991: Joseph Sodroski; W Haseltine; M Kowalski
Role of the human immunodeficiency virus type I envelope glycoprotein in cytopathic effect.
Advances in experimental medicine and biology 1991;300():193-9; discussion 200-1.
1991: M Kowalski; L Bergeron; Tatyana Dorfman; W Haseltine; Joseph Sodroski
Attenuation of human immunodeficiency virus type 1 cytopathic effect by a mutation affecting the transmembrane envelope glycoprotein.
Journal of virology 1991;65(1):281-91.
1991: M C Poznansky; B Walker; W A Haseltine; Joseph Sodroski; E Langhoff
A rapid method for quantitating the frequency of peripheral blood cells containing HIV-1 DNA.
Journal of acquired immune deficiency syndromes 1991;4(4):368-73.
1990: E Helseth; U Olshevsky; Dana Gabuzda; Blair Ardman; W Haseltine; Joseph Sodroski
Changes in the transmembrane region of the human immunodeficiency virus type 1 gp41 envelope glycoprotein affect membrane fusion.
Journal of virology 1990;64(12):6314-8.
1990: U Olshevsky; E Helseth; C Furman; J Li; W Haseltine; Joseph Sodroski
Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding.
Journal of virology 1990;64(12):5701-7.
1990: Y C Lu; N Touzjian; M Stenzel; Tatyana Dorfman; Joseph Sodroski; W A Haseltine
Identification of cis-acting repressive sequences within the negative regulatory element of human immunodeficiency virus type 1.
Journal of virology 1990;64(10):5226-9.
1990: E A Cohen; G Dehni; Joseph Sodroski; W A Haseltine
Human immunodeficiency virus vpr product is a virion-associated regulatory protein.
Journal of virology 1990;64(6):3097-9.
1990: E Helseth; M Kowalski; Dana Gabuzda; U Olshevsky; W Haseltine; Joseph Sodroski
Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants.
Journal of virology 1990;64(5):2416-20.
1990: H T Poteat; F Y Chen; P Kadison; Joseph Sodroski; W A Haseltine
Protein kinase A-dependent binding of a nuclear factor to the 21-base-pair repeat of the human T-cell leukemia virus type I long terminal repeat.
Journal of virology 1990;64(3):1264-70.
1990: J Salfeld; Heinrich G Göttlinger; R A Sia; R E Park; Joseph Sodroski; W A Haseltine
A tripartite HIV-1 tat-env-rev fusion protein.
The EMBO journal 1990;9(3):965-70.
1990: E F Terwilliger; Joseph Sodroski; W A Haseltine
Mechanisms of infectivity and replication of HIV-1 and implications for therapy.
Annals of emergency medicine 1990;19(3):233-41.
1990: E A Cohen; Y Lu; Heinrich G Göttlinger; G Dehni; Y Jalinoos; Joseph Sodroski; W A Haseltine
The T open reading frame of human immunodeficiency virus type 1.
Journal of acquired immune deficiency syndromes 1990;3(6):601-8.
1990: Blair Ardman; M Kowalski; J Bristol; W Haseltine; Joseph Sodroski
Effects on CD4 binding of anti-peptide sera to the fourth and fifth conserved domains of HIV-1 gp120.
Journal of acquired immune deficiency syndromes 1990;3(3):206-14.
1990: E Zazopoulos; Joseph Sodroski; W A Haseltine
p21rex protein of HTLV-1.
Journal of acquired immune deficiency syndromes 1990;3(12):1135-9.
1990: A Caputo; Joseph Sodroski; W A Haseltine
Constitutive expression of HIV-1 tat protein in human Jurkat T cells using a BK virus vector.
Journal of acquired immune deficiency syndromes 1990;3(4):372-9.
1990: E A Cohen; E F Terwilliger; Y Jalinoos; J Proulx; Joseph Sodroski; W A Haseltine
Identification of HIV-1 vpr product and function.
Journal of acquired immune deficiency syndromes 1990;3(1):11-8.
1989: Y Lu; M Stenzel; Joseph Sodroski; W A Haseltine
Effects of long terminal repeat mutations on human immunodeficiency virus type 1 replication.
Journal of virology 1989;63(9):4115-9.
1989: A Lever; Heinrich Gottlinger; W Haseltine; Joseph Sodroski
Identification of a sequence required for efficient packaging of human immunodeficiency virus type 1 RNA into virions.
Journal of virology 1989;63(9):4085-7.
1989: Heinrich G Göttlinger; Joseph Sodroski; W A Haseltine
Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(15):5781-5.
1989: E F Terwilliger; E A Cohen; Y C Lu; Joseph Sodroski; W A Haseltine
Functional role of human immunodeficiency virus type 1 vpu.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(13):5163-7.
1989: Andre Rosowsky; V C Solan; Joseph Sodroski; Ruth Ruprecht
Synthesis of the 2-chloro analogues of 3'-deoxyadenosine, 2',3'-dideoxyadenosine, and 2',3'-didehydro-2',3'-dideoxyadenosine as potential antiviral agents.
Journal of medicinal chemistry 1989;32(5):1135-40.
1989: E F Terwilliger; B Godin; Joseph Sodroski; W A Haseltine
Construction and use of a replication-competent human immunodeficiency virus (HIV-1) that expresses the chloramphenicol acetyltransferase enzyme.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(10):3857-61.
1989: Ralph Grassmann; C Dengler; I Müller-Fleckenstein; Bernhard Fleckenstein; K McGuire; M C Dokhelar; Joseph Sodroski; W A Haseltine
Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a Herpesvirus saimiri vector.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3351-5.
1989: M Kowalski; Blair Ardman; L Basiripour; Y C Lu; D Blohm; W Haseltine; Joseph Sodroski
Antibodies to CD4 in individuals infected with human immunodeficiency virus type 1.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3346-50.
1989: H T Poteat; P Kadison; K McGuire; L Park; R E Park; Joseph Sodroski; W A Haseltine
Response of the human T-cell leukemia virus type 1 long terminal repeat to cyclic AMP.
Journal of virology 1989;63(4):1604-11.
1989: M C Dokhelar; H Pickford; Joseph Sodroski; W A Haseltine
HTLV-I p27rex regulates gag and env protein expression.
Journal of acquired immune deficiency syndromes 1989;2(5):431-40.
1989: K Kozarsky; Marsha Penman; L Basiripour; W Haseltine; Joseph Sodroski; Monty Krieger
Glycosylation and processing of the human immunodeficiency virus type 1 envelope protein.
Journal of acquired immune deficiency syndromes 1989;2(2):163-9.
1989: M C Dokhelar; H Pickford; Joseph Sodroski; W A Haseltine
The potential for homeostatic regulation of the X region proteins of the human T cell leukemia virus type I.
Journal of acquired immune deficiency syndromes 1989;2(6):588-94.
1988: E A Cohen; E F Terwilliger; Joseph Sodroski; W A Haseltine
Identification of a protein encoded by the vpu gene of HIV-1.
Nature 1988;334(6182):532-4.
1988: B R Cullen; J Hauber; K Campbell; Joseph Sodroski; W A Haseltine; C A Rosen
Subcellular localization of the human immunodeficiency virus trans-acting art gene product.
Journal of virology 1988;62(7):2498-501.
1988: C A Rosen; E Terwilliger; A Dayton; Joseph Sodroski; W A Haseltine
Intragenic cis-acting art gene-responsive sequences of the human immunodeficiency virus.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(7):2071-5.
1988: E Terwilliger; R Burghoff; R Sia; Joseph Sodroski; W Haseltine; C Rosen
The art gene product of human immunodeficiency virus is required for replication.
Journal of virology 1988;62(2):655-8.
1988: Rebecca E Hussey; N E Richardson; M Kowalski; N R Brown; Hsiu-Ching Chang; Robert Siliciano; Tatyana Dorfman; B Walker; Joseph Sodroski; Ellis L Reinherz
A soluble CD4 protein selectively inhibits HIV replication and syncytium formation.
Nature 1988;331(6151):78-81.
1988: E Terwilliger; J Proulx; Joseph Sodroski; W A Haseltine
Cell lines that express stably env gene products from three strains of HIV-1.
Journal of acquired immune deficiency syndromes 1988;1(4):317-23.
1988: A I Dayton; E F Terwilliger; J Potz; M Kowalski; Joseph Sodroski; W A Haseltine
Cis-acting sequences responsive to the rev gene product of the human immunodeficiency virus.
Journal of acquired immune deficiency syndromes 1988;1(5):441-52.
1987: Bruce D Walker; M Kowalski; W C Goh; K Kozarsky; M Krieger; C Rosen; L Rohrschneider; W A Haseltine; Joseph Sodroski
Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(22):8120-4.
1987: Joseph Mosca; D P Bednarik; N B Raj; C A Rosen; Joseph Sodroski; W A Haseltine; Gary S Hayward; PAULA PITHA-ROWE
Activation of human immunodeficiency virus by herpesvirus infection: identification of a region within the long terminal repeat that responds to a trans-acting factor encoded by herpes simplex virus 1.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(21):7408-12.
1987: M Kowalski; J Potz; L Basiripour; Tatyana Dorfman; W C Goh; E Terwilliger; A Dayton; C Rosen; W Haseltine; Joseph Sodroski
Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1.
Science (New York, N.Y.) 1987;237(4820):1351-5.
1987: C A Rosen; R Park; Joseph Sodroski; W A Haseltine
Multiple sequence elements are required for regulation of human T-cell leukemia virus gene expression.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(14):4919-23.
1987: Joseph Sodroski; M Kowalski; Tatyana Dorfman; L Basiripour; C Rosen; W Haseltine
HIV envelope-CD4 interaction not inhibited by synthetic octapeptides.
Lancet 1987;1(8547):1428-9.
1987: Warner Greene; Warren J Leonard; Y Wano; P B Svetlik; N J Peffer; Joseph Sodroski; C A Rosen; W C Goh; W A Haseltine
Trans-activator gene of HTLV-II: interpretation.
Science (New York, N.Y.) 1987;235(4792):1073.
1987: W C Goh; Joseph Sodroski; C A Rosen; W A Haseltine
Expression of the art gene protein of human T-lymphotropic virus type III (HTLV-III/LAV) in bacteria.
Journal of virology 1987;61(2):633-7.
1987: R Patarca; C Heath; G J Goldenberg; C A Rosen; Joseph Sodroski; W A Haseltine; U M Hansen
Transcription directed by the HIV long terminal repeat in vitro.
AIDS research and human retroviruses 1987;3(1):41-55.
1987: Joseph Mosca; D P Bednarik; N B Raj; C A Rosen; Joseph Sodroski; W A Haseltine; PAULA PITHA-ROWE
Herpes simplex virus type-1 can reactivate transcription of latent human immunodeficiency virus.
Nature 1987;325(6099):67-70.
1987: W Haseltine; Joseph Sodroski; C Rosen
Replication and pathogenesis of the human T-cell leukemia/lymphotropic retroviruses.
Haematology and blood transfusion 1987;31():395-403.
1987: L Ratner; Joseph Sodroski; F Wong-Staal; W A Haseltine; G M Shaw; Robert C Gallo
Mechanism of leukemogenesis by human T-cell leukemia virus types I and II: role of the lor gene.
Cancer detection and prevention 1987;10(5-6):411-24.
1986: E Terwilliger; Joseph Sodroski; C A Rosen; W A Haseltine
Effects of mutations within the 3' orf open reading frame region of human T-cell lymphotropic virus type III (HTLV-III/LAV) on replication and cytopathogenicity.
Journal of virology 1986;60(2):754-60.
1986: C A Rosen; Joseph Sodroski; L Willems; R Kettmann; K Campbell; R Zaya; A Burny; W A Haseltine
The 3' region of bovine leukemia virus genome encodes a trans-activator protein.
The EMBO journal 1986;5(10):2585-9.
1986: Naoko Tanese; Joseph Sodroski; W A Haseltine; S P Goff
Expression of reverse transcriptase activity of human T-lymphotropic virus type III (HTLV-III/LAV) in Escherichia coli.
Journal of virology 1986;59(3):743-5.
1986: Joseph Sodroski; W C Goh; C Rosen; K Campbell; W A Haseltine
Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity.
Nature 1986;322(6078):470-4.
1986: W C Goh; C Rosen; Joseph Sodroski; D D Ho; W A Haseltine
Identification of a protein encoded by the trans activator gene tatIII of human T-cell lymphotropic retrovirus type III.
Journal of virology 1986;59(1):181-4.
1986: Joseph Sodroski; W C Goh; C Rosen; A Dayton; E Terwilliger; W Haseltine
A second post-transcriptional trans-activator gene required for HTLV-III replication.
Nature 1986;321(6068):412-7.
1986: Warner Greene; Warren J Leonard; Y Wano; P B Svetlik; N J Peffer; Joseph Sodroski; C A Rosen; W C Goh; W A Haseltine
Trans-activator gene of HTLV-II induces IL-2 receptor and IL-2 cellular gene expression.
Science (New York, N.Y.) 1986;232(4752):877-80.
1986: Joseph Sodroski; W C Goh; C Rosen; A Tartar; D Portetelle; A Burny; W Haseltine
Replicative and cytopathic potential of HTLV-III/LAV with sor gene deletions.
Science (New York, N.Y.) 1986;231(4745):1549-53.
1986: A I Dayton; Joseph Sodroski; C A Rosen; W C Goh; W A Haseltine
The trans-activator gene of the human T cell lymphotropic virus type III is required for replication.
Cell 1986;44(6):941-7.
1986: C A Rosen; Joseph Sodroski; R Kettman; W A Haseltine
Activation of enhancer sequences in type II human T-cell leukemia virus and bovine leukemia virus long terminal repeats by virus-associated trans-acting regulatory factors.
Journal of virology 1986;57(3):738-44.
1986: C A Rosen; Joseph Sodroski; W C Goh; A I Dayton; J Lippke; W A Haseltine
Post-transcriptional regulation accounts for the trans-activation of the human T-lymphotropic virus type III.
Nature 1986;319(6054):555-9.
1986: W A Haseltine; Joseph Sodroski; C A Rosen
Control of gene expression and the replication and pathogenesis of retroviruses.
Important advances in oncology 1986;():159-72.
1986: C A Rosen; Joseph Sodroski; K Campbell; W A Haseltine
Construction of recombinant murine retroviruses that express the human T-cell leukemia virus type II and human T-cell lymphotropic virus type III trans activator genes.
Journal of virology 1986;57(1):379-84.
1985: C A Rosen; Joseph Sodroski; W A Haseltine
Location of cis-acting regulatory sequences in the human T-cell leukemia virus type I long terminal repeat.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(19):6502-6.
1985: Joseph Sodroski; W C Goh; C A Rosen; S Z Salahuddin; A Aldovini; G Franchini; F Wong-Staal; Robert C Gallo; K Sugamura; Y Hinuma
trans-Activation of the human T-cell leukemia virus long terminal repeat correlates with expression of the x-lor protein.
Journal of virology 1985;55(3):831-5.
1985: W A Haseltine; Joseph Sodroski; C Rosen
The lor gene and pathogenesis of HTLV-I, -II, and -III.
Cancer research 1985;45(9 Suppl):4545s-4549s.
1985: W C Goh; Joseph Sodroski; C Rosen; W Haseltine
Expression of the x-lor gene of human T-cell leukemia virus I in Escherichia coli.
Journal of virology 1985;55(2):497-9.
1985: Joseph Sodroski; R Patarca; C Rosen; F Wong-Staal; W Haseltine
Location of the trans-activating region on the genome of human T-cell lymphotropic virus type III.
Science (New York, N.Y.) 1985;229(4708):74-7.
1985: C A Rosen; Joseph Sodroski; W A Haseltine
The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat.
Cell 1985;41(3):813-23.
1985: Joseph Sodroski; C Rosen; W C Goh; W Haseltine
A transcriptional activator protein encoded by the x-lor region of the human T-cell leukemia virus.
Science (New York, N.Y.) 1985;228(4706):1430-4.
1985: J S Allan; J E Coligan; F Barin; Mary Fran McLane; Joseph Sodroski; C A Rosen; W A Haseltine; T H Lee; M Essex
Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III.
Science (New York, N.Y.) 1985;228(4703):1091-4.
1985: W C Goh; Joseph Sodroski; C Rosen; M Essex; W A Haseltine
Subcellular localization of the product of the long open reading frame of human T-cell leukemia virus type I.
Science (New York, N.Y.) 1985;227(4691):1227-8.
1985: C A Rosen; Joseph Sodroski; R Kettman; A Burny; W A Haseltine
Trans activation of the bovine leukemia virus long terminal repeat in BLV-infected cells.
Science (New York, N.Y.) 1985;227(4684):320-2.
1985: Joseph Sodroski; C Rosen; F Wong-Staal; S Z Salahuddin; M Popovic; S Arya; Robert C Gallo; W A Haseltine
Trans-acting transcriptional regulation of human T-cell leukemia virus type III long terminal repeat.
Science (New York, N.Y.) 1985;227(4683):171-3.
1985: W A Haseltine; Joseph Sodroski; R Patarca
Structure and function of the genome of HTLV.
Current topics in microbiology and immunology 1985;115():177-209.
1984: S F Josephs; F Wong-Staal; V Manzari; Robert C Gallo; Joseph Sodroski; M D Trus; D Perkins; R Patarca; W A Haseltine
Long terminal repeat structure of an American isolate of type I human T-cell leukemia virus.
Virology 1984;139(2):340-5.
1984: T H Lee; J E Coligan; Mary Fran McLane; Joseph Sodroski; M Popovic; F Wong-Staal; Robert C Gallo; W Haseltine; M Essex
Serological cross-reactivity between envelope gene products of type I and type II human T-cell leukemia virus.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(23):7579-83.
1984: T H Lee; J E Coligan; Joseph Sodroski; W A Haseltine; S Z Salahuddin; F Wong-Staal; Robert C Gallo; M Essex
Antigens encoded by the 3'-terminal region of human T-cell leukemia virus: evidence for a functional gene.
Science (New York, N.Y.) 1984;226(4670):57-61.
1984: Joseph Sodroski; M Trus; D Perkins; R Patarca; F Wong-Staal; E Gelmann; Robert C Gallo; W A Haseltine
Repetitive structure in the long-terminal-repeat element of a type II human T-cell leukemia virus.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(15):4617-21.
1984: W A Haseltine; Joseph Sodroski; R Patarca; D Briggs; D Perkins; F Wong-Staal
Structure of 3' terminal region of type II human T lymphotropic virus: evidence for new coding region.
Science (New York, N.Y.) 1984;225(4660):419-21.
1984: Joseph Sodroski; C A Rosen; W A Haseltine
Trans-acting transcriptional activation of the long terminal repeat of human T lymphotropic viruses in infected cells.
Science (New York, N.Y.) 1984;225(4660):381-5.
1984: Joseph Sodroski; R Patarca; D Perkins; D Briggs; T H Lee; M Essex; J Coligan; F Wong-Staal; Robert C Gallo; W A Haseltine
Sequence of the envelope glycoprotein gene of type II human T lymphotropic virus.
Science (New York, N.Y.) 1984;225(4660):421-4.
1984: Joseph Sodroski; W C Goh; W A Haseltine
Transforming potential of a human protooncogene (c-fps/fes) locus.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(10):3039-43.
1984: W A Haseltine; Joseph Sodroski; C Rosen
Structure and function of human leukemia and AIDS viruses.
Princess Takamatsu symposia 1984;15():187-96.
1983: toby horn; Joseph Sodroski; P K Qasba
Protein-coding capacities of polyadenylated RNAs from normal and neoplastic rat mammary tissues.
Cancer research 1983;43(4):1819-26.
1982: M D Trus; Joseph Sodroski; W A Haseltine
Isolation and characterization of a human locus homologous to the transforming gene (v-fes) of feline sarcoma virus.
The Journal of biological chemistry 1982;257(6):2730-3.