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Toshio Sofuni
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54
Hayashi, Makoto
27
Nohmi, Takehiko
23
Suzuki, Takayoshi
22
Honma, Masamitsu
17
Matsuoka, Atsuko
14
Yamada, Masami
9
Matsui, Keiko
7
Sakamoto, Hiroko
6
Shimada, Hiroyasu
5
Nakadate, M
5
Ishidate, Motoi
4
Furukawa, Fumio
4
Masumura, Ken-ichi
4
Takahashi, Mika
4
Ueda, Otoya
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All Publications
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2009: Morita Takeshi; Hayashi Makoto; Nakajima Madoka; Tanaka Noriho; Tweats David J; Morikawa Kaoru; Sofuni Toshio
Practical issues on the application of the GHS classification criteria for germ cell mutagens.
Regulatory toxicology and pharmacology : RTP 2009;55(1):52-68.
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2007: Tweats D J; Blakey D; Heflich R H; Jacobs A; Jacobsen S D; Morita T; Nohmi T; O'Donovan M R; Sasaki Y F; Sofuni T; Tice R;
Report of the IWGT working group on strategies and interpretation of regulatory in vivo tests I. Increases in micronucleated bone marrow cells in rodents that do not indicate genotoxic hazards.
Mutation research 2007;627(1):78-91.
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2007: Tweats D J; Blakey D; Heflich R H; Jacobs A; Jacobsen S D; Morita T; Nohmi T; O'Donovan M R; Sasaki Y F; Sofuni T; Tice R;
Report of the IWGT working group on strategy/interpretation for regulatory in vivo tests II. Identification of in vivo-only positive compounds in the bone marrow micronucleus test.
Mutation research 2007;627(1):92-105.
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2004: Satoh T; Yamamoto K; Miura K F; Sofuni T
Region-specific chromatin decondensation and micronucleus formation induced by 5-azacytidine in human TIG-7 cells.
Cytogenetic and genome research 2004;104(1-4):289-94.
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2003: Kirsch-Volders Micheline; Sofuni Toshio; Aardema Marilyn; Albertini Silvio; Eastmond David; Fenech Michael; Ishidate Motoi; Kirchner Stephan; Lorge Elisabeth; Morita Takeshi; Norppa Hannu; Surrallés Jordi; Vanhauwaert Annelies; Wakata Akihiro
Report from the in vitro micronucleus assay working group.
Mutation research 2003;540(2):153-63.
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2002: Honma Masamitsu; Tadokoro Satoshi; Sakamoto Hiroko; Tanabe Hideyuki; Sugimoto Masanobu; Furuichi Yasuhiro; Satoh Takatomo; Sofuni Toshio; Goto Makoto; Hayashi Makoto
Chromosomal instability in B-lymphoblasotoid cell lines from Werner and Bloom syndrome patients.
Mutation research 2002;520(1-2):15-24.
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2002: Kusakabe Hirokazu; Yamakage Kohji; Wakuri Shinobu; Sasaki Kiyoshi; Nakagawa Yuzuki; Watanabe Mika; Hayashi Makoto; Sofuni Toshio; Ono Hiroshi; Tanaka Noriho
Relevance of chemical structure and cytotoxicity to the induction of chromosome aberrations based on the testing results of 98 high production volume industrial chemicals.
Mutation research 2002;517(1-2):187-98.
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2002: Noda Yasuhiro; Suzuki Takayoshi; Kohara Arihiro; Hasegawa Akira; Yotsuyanagi Toshihisa; Hayashi Makoto; Sofuni Toshio; Yamanaka Kenzo; Okada Shoji
In vivo genotoxicity evaluation of dimethylarsinic acid in MutaMouse.
Mutation research 2002;513(1-2):205-12.
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2001: Honma M; Momose M; Sakamoto H; Sofuni T; Hayashi M
Spindle poisons induce allelic loss in mouse lymphoma cells through mitotic non-disjunction.
Mutation research 2001;493(1-2):101-14.
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2000: Suzuki T; Wang X; Miyata Y; Saeki K; Kohara A; Kawazoe Y; Hayashi M; Sofuni T
Hepatocarcinogen quinoline induces G:C to C:G transversions in the cII gene in the liver of lambda/lacZ transgenic mice (MutaMouse).
Mutation research 2000;456(1-2):73-81.
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2000: Honma M; Momose M; Tanabe H; Sakamoto H; Yu Y; Little J B; Sofuni T; Hayashi M
Requirement of wild-type p53 protein for maintenance of chromosomal integrity.
Molecular carcinogenesis 2000;28(4):203-14.
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2000: Itoh T; Suzuki T; Nishikawa A; Furukawa F; Takahashi M; Xue W; Sofuni T; Hayashi M
In vivo genotoxicity of 2-amino-3,8-dimethylimidazo[4, 5-f]quinoxaline in lacI transgenic (Big Blue) mice.
Mutation research 2000;468(1):19-25.
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2000: Sofuni T; Hayashi M; Nohmi T; Matsuoka A; Yamada M; Kamata E
Semi-quantitative evaluation of genotoxic activity of chemical substances and evidence for a biological threshold of genotoxic activity.
Mutation research 2000;464(1):97-104.
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2000: Kirsch-Volders M; Sofuni T; Aardema M; Albertini S; Eastmond D; Fenech M; Ishidate M; Lorge E; Norppa H; Surrallés J; von der Hude W; Wakata A
Report from the In Vitro Micronucleus Assay Working Group.
Environmental and molecular mutagenesis 2000;35(3):167-72.
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1999: Matsushima T; Hayashi M; Matsuoka A; Ishidate M; Miura K F; Shimizu H; Suzuki Y; Morimoto K; Ogura H; Mure K; Koshi K; Sofuni T
Validation study of the in vitro micronucleus test in a Chinese hamster lung cell line (CHL/IU).
Mutagenesis 1999;14(6):569-80.
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1999: Masumura K; Matsui K; Yamada M; Horiguchi M; Ishida K; Watanabe M; Ueda O; Suzuki H; Kanke Y; Tindall K R; Wakabayashi K; Sofuni T; Nohmi T
Mutagenicity of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) in the new gpt delta transgenic mouse.
Cancer letters 1999;143(2):241-4.
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1999: Suzuki T; Uno Y; Idehara K; Baba T; Maniwa J; Ohkouchi A; Wang X; Hayashi M; Sofuni T; Tsuruoka M; Miyajima H; Kondo K
Procarbazine genotoxicity in the MutaMouse; strong clastogenicity and organ-specific induction of lacZ mutations.
Mutation research 1999;444(2):269-81.
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1999: Saitoh M; Umemura T; Kawasaki Y; Momma J; Matsushima Y; Sakemi K; Isama K; Kitajima S; Ogawa Y; Hasegawa R; Suzuki T; Hayashi M; Inoue T; Ohno Y; Sofuni T; Kurokawa Y; Tsuda M
Toxicity study of a rubber antioxidant, mixture of 2-mercaptomethylbenzimidazoles, by repeated oral administration to rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1999;37(7):777-87.
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1999: Matsuoka A; Matsuura K; Sakamoto H; Hayashi M; Sofuni T
A proposal for a simple way to distinguish aneugens from clastogens in the in vitro micronucleus test.
Mutagenesis 1999;14(4):385-9.
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1999: Espinosa-Aguirre J J; Yamada M; Matsui K; Watanabe M; Sofuni T; Nohmi T
New O-acetyltransferase-deficient Ames Salmonella strains generated by specific gene disruption.
Mutation research 1999;439(2):159-69.
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1999: Honma M; Zhang L Z; Sakamoto H; Ozaki M; Takeshita K; Momose M; Hayashi M; Sofuni T
The need for long-term treatment in the mouse lymphoma assay.
Mutagenesis 1999;14(1):23-9.
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1999: Honma M; Hayashi M; Shimada H; Tanaka N; Wakuri S; Awogi T; Yamamoto K I; Kodani N; Nishi Y; Nakadate M; Sofuni T
Evaluation of the mouse lymphoma tk assay (microwell method) as an alternative to the in vitro chromosomal aberration test.
Mutagenesis 1999;14(1):5-22.
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1999: Horiguchi M; Masumura K; Ikehata H; Ono T; Kanke Y; Sofuni T; Nohmi T
UVB-induced gpt mutations in the skin of gpt delta transgenic mice.
Environmental and molecular mutagenesis 1999;34(2-3):72-9.
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1999: Nohmi T; Suzuki M; Masumura K; Yamada M; Matsui K; Ueda O; Suzuki H; Katoh M; Ikeda H; Sofuni T
Spi(-) selection: An efficient method to detect gamma-ray-induced deletions in transgenic mice.
Environmental and molecular mutagenesis 1999;34(1):9-15.
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1999: Masumura K; Matsui M; Katoh M; Horiya N; Ueda O; Tanabe H; Yamada M; Suzuki H; Sofuni T; Nohmi T
Spectra of gpt mutations in ethylnitrosourea-treated and untreated transgenic mice.
Environmental and molecular mutagenesis 1999;34(1):1-8.
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1998: Wang X; Suzuki T; Itoh T; Honma M; Nishikawa A; Furukawa F; Takahashi M; Hayashi M; Kato T; Sofuni T
Specific mutational spectrum of dimethylnitrosamine in the lacI transgene of Big Blue C57BL/6 mice.
Mutagenesis 1998;13(6):625-30.
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1998: Matsuoka A; Matsuura K; Sakamoto H; Hayashi M; Sofuni T
Spindle disturbances induced by benzo[a]pyrene and 7, 12-dimethylbenz[a]anthracene in a Chinese hamster cell line (V79-MZ) and the stability of the numerical chromosome aberrations that follow.
Mutation research 1998;419(1-3):1-12.
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1998: Watanabe M; Nishino T; Takio K; Sofuni T; Nohmi T
Purification and characterization of wild-type and mutant "classical" nitroreductases of Salmonella typhimurium. L33R mutation greatly diminishes binding of FMN to the nitroreductase of S. typhimurium.
The Journal of biological chemistry 1998;273(37):23922-8.
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1998: Ishidate M; Miura K F; Sofuni T
Chromosome aberration assays in genetic toxicology testing in vitro.
Mutation research 1998;404(1-2):167-72.
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1998: Hayashi M; Ueda T; Uyeno K; Wada K; Kinae N; Saotome K; Tanaka N; Takai A; Sasaki Y F; Asano N; Sofuni T; Ojima Y
Development of genotoxicity assay systems that use aquatic organisms.
Mutation research 1998;399(2):125-33.
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1998: Gruz P; Matsui K; Sofuni T; Nohmi T
Roles of the mutagenesis proteins SamA'B and MucA'B in chemically induced frameshift mutagenesis in Salmonella typhimurium hisD3052.
Mutation research 1998;398(1-2):33-42.
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1998: Suzuki T; Miyata Y; Saeki K; Kawazoe Y; Hayashi M; Sofuni T
In vivo mutagenesis by the hepatocarcinogen quinoline in the lacZ transgenic mouse: evidence for its in vivo genotoxicity.
Mutation research 1998;412(2):161-6.
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1998: Inoue T; Ohno Y; Takahshi M; Sofuni T; Nakadate M; Korokawa Y
[Studies on development and improvement of toxicity guidelines conducted at the Biological Safety Research Center]
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 1998;(116):149-52.
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1997: Suzuki T; Hayashi M; Wang X; Yamamoto K; Ono T; Myhr B C; Sofuni T
A comparison of the genotoxicity of ethylnitrosourea and ethyl methanesulfonate in lacZ transgenic mice (Muta Mouse).
Mutation research 1997;395(1):75-82.
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1997: Yamada M; Matsui K; Sofuni T; Nohmi T
New tester strains of Salmonella typhimurium lacking O6-methylguanine DNA methyltransferases and highly sensitive to mutagenic alkylating agents.
Mutation research 1997;381(1):15-24.
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1997: Suzuki M; Matsui K; Yamada M; Kasai H; Sofuni T; Nohmi T
Construction of mutants of Salmonella typhimurium deficient in 8-hydroxyguanine DNA glycosylase and their sensitivities to oxidative mutagens and nitro compounds.
Mutation research 1997;393(3):233-46.
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1997: Matsuoka A; Ozaki M; Takeshita K; Sakamoto H; Glatt H R; Hayashi M; Sofuni T
Aneuploidy induction by benzo[a]pyrene and polyploidy induction by 7,12-dimethylbenz[a]anthracene in Chinese hamster cell lines V79-MZ and V79.
Mutagenesis 1997;12(5):365-72.
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1997: Sasaki Y F; Izumiyama F; Nishidate E; Ishibashi S; Tsuda S; Matsusaka N; Asano N; Saotome K; Sofuni T; Hayashi M
Detection of genotoxicity of polluted sea water using shellfish and the alkaline single-cell gel electrophoresis (SCE) assay: a preliminary study.
Mutation research 1997;393(1-2):133-9.
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1997: Nishikawa A; Furukawa F; Kasahara K; Lee I S; Suzuki T; Hayashi M; Sofuni T; Takahashi M
Comparative study on organ-specificity of tumorigenicity, mutagenicity and cell proliferative activity induced by dimethylnitrosamine in Big Blue mice.
Cancer letters 1997;117(2):143-7.
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1997: Honma M; Zhang L S; Hayashi M; Takeshita K; Nakagawa Y; Tanaka N; Sofuni T
Illegitimate recombination leading to allelic loss and unbalanced translocation in p53-mutated human lymphoblastoid cells.
Molecular and cellular biology 1997;17(8):4774-81.
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1997: Yamada M; Espinosa-Aguirre J J; Watanabe M; Matsui K; Sofuni T; Nohmi T
Targeted disruption of the gene encoding the classical nitroreductase enzyme in Salmonella typhimurium Ames test strains TA1535 and TA1538.
Mutation research 1997;375(1):9-17.
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1997: Honma M; Hayashi M; Hackman P; Sofuni T
Chlorambucil-induced structural changes in the gpt gene of AS52 cells.
Mutation research 1997;389(2-3):199-205.
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1997: Honma M; Hayashi M; Sofuni T
Cytotoxic and mutagenic responses to X-rays and chemical mutagens in normal and p53-mutated human lymphoblastoid cells.
Mutation research 1997;374(1):89-98.
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1997: Morita T; Asano N; Awogi T; Sasaki Y F; Sato S; Shimada H; Sutou S; Suzuki T; Wakata A; Sofuni T; Hayashi M
Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (groups 1, 2A and 2B) the summary report of the 6th collaborative study by CSGMT/JEMS MMS. Collaborative Study of the Micronucleus Group Test. Mammalian Mutagenicity Study Group.
Mutation research 1997;389(1):3-122.
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1997: Suzuki T; Itoh S; Takemoto N; Yajima N; Miura M; Hayashi M; Shimada H; Sofuni T
Ethyl nitrosourea and methyl methanesulfonate mutagenicity in sperm and testicular germ cells of lacZ transgenic mice (Muta Mouse).
Mutation research 1997;388(2-3):155-63.
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1997: Sofuni T; Wilcox P; Shimada H; Clements J; Honma M; Clive D; Green M; Thybaud V; San R H; Elliott B M; Müller L
Mouse lymphoma workshop: Victoria, British Columbia, Canada, March 27, 1996 protocol issues regarding the use of the Microwell Method of the Mouse Lymphoma Assay.
Environmental and molecular mutagenesis 1997;29(4):434-8.
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1997: Galloway S M; Sofuni T; Shelby M D; Thilagar A; Kumaroo V; Kaur P; Gulati D; Putman D L; Murli H; Marshall R; Tanaka N; Anderson B; Zeiger E; Ishidate M
Multilaboratory comparison of in vitro tests for chromosome aberrations in CHO and CHL cells tested under the same protocols.
Environmental and molecular mutagenesis 1997;29(2):189-207.
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1996: Matsui M; Matsui K; Kawasaki Y; Oda Y; Noguchi T; Kitagawa Y; Sawada M; Hayashi M; Nohmi T; Yoshihira K; Ishidate M; Sofuni T
Evaluation of the genotoxicity of stevioside and steviol using six in vitro and one in vivo mutagenicity assays.
Mutagenesis 1996;11(6):573-9.
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1996: Matsui M; Sofuni T; Nohmi T
Regionally-targeted mutagenesis by metabolically-activated steviol: DNA sequence analysis of steviol-induced mutants of guanine phosphoribosyltransferase (gpt) gene of Salmonella typhimurium TM677.
Mutagenesis 1996;11(6):565-72.
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1996: Zhang L S; Honma M; Matsuoka A; Suzuki T; Sofuni T; Hayashi M
Chromosome painting analysis of spontaneous and methyl methanesulfonate-induced trifluorothymidine-resistant L5178Y cell colonies.
Mutation research 1996;370(3-4):181-90.
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1996: Matsuoka A; Yamakage K; Kusakabe H; Wakuri S; Asakura M; Noguchi T; Sugiyama T; Shimada H; Nakayama S; Kasahara Y; Takahashi Y; Miura K F; Hatanaka M; Ishidate M; Morita T; Watanabe K; Hara M; Odawara K; Tanaka N; Hayashi M; Sofuni T
Re-evaluation of chromosomal aberration induction on nine mouse lymphoma assay "unique positive' NTP carcinogens.
Mutation research 1996;369(3-4):243-52.
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1996: Gruz P; Matsui K; Sofuni T; Nohmi T
Construction of a new system for separate expression of mutagenesis proteins: the abilities to promote UV mutagenesis and interchangeability of MucA', MucB, SamA' and SamB proteins in Salmonella typhimurium.
Mutation research 1996;354(2):157-70.
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1996: Suzuki T; Hayashi M; Ochiai M; Wakabayashi K; Ushijima T; Sugimura T; Nagao M; Sofuni T
Organ variation in the mutagenicity of MeIQ in Big Blue lacI transgenic mice.
Mutation research 1996;369(1-2):45-9.
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1996: Sofuni T; Honma M; Hayashi M; Shimada H; Tanaka N; Wakuri S; Awogi T; Yamamoto K I; Nishi Y; Nakadate M
Detection of in vitro clastogens and spindle poisons by the mouse lymphoma assay using the microwell method: interim report of an international collaborative study.
Mutagenesis 1996;11(4):349-55.
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1996: Nohmi T; Katoh M; Suzuki H; Matsui M; Yamada M; Watanabe M; Suzuki M; Horiya N; Ueda O; Shibuya T; Ikeda H; Sofuni T
A new transgenic mouse mutagenesis test system using Spi- and 6-thioguanine selections.
Environmental and molecular mutagenesis 1996;28(4):465-70.
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1996: Sofuni T; Suzuki T; Hayashi M
Initial consideration for use of transgenic mutation assays in a regulatory submission.
Environmental and molecular mutagenesis 1996;28(4):443-6.
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1996: Suzuki T; Itoh T; Hayashi M; Nishikawa Y; Ikezaki S; Furukawa F; Takahashi M; Sofuni T
Organ variation in the mutagenicity of dimethylnitrosamine in Big Blue mice.
Environmental and molecular mutagenesis 1996;28(4):348-53.
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1995: Ono T; Miyamura Y; Ikehata H; Yamanaka H; Kurishita A; Yamamoto K; Suzuki T; Nohmi T; Hayashi M; Sofuni T
Spontaneous mutant frequency of lacZ gene in spleen of transgenic mouse increases with age.
Mutation research 1995;338(1-6):183-8.
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1995: Hayashi M; Sofuni T
A reaction to 'A sequential approach to testing with the rodent bone marrow micronucleus assay'.
Mutation research 1995;331(1):173-4.
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1995: Zhang L S; Honma M; Hayashi M; Suzuki T; Matsuoka A; Sofuni T
A comparative study of TK6 human lymphoblastoid and L5178Y mouse lymphoma cell lines in the in vitro micronucleus test.
Mutation research 1995;347(3-4):105-15.
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1995: Nohmi T; Yamada M; Matsui K; Watanabe M; Sofuni T
Specific disruption of samAB genes in a 60-megadalton cryptic plasmid of Salmonella typhimurium.
Mutation research 1995;329(1):1-9.
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1995: Nohmi T; Yamada M; Matsui M; Matsui K; Watanabe M; Sofuni T
Involvement of umuDCST genes in nitropyrene-induced -CG frameshift mutagenesis at the repetitive CG sequence in the hisD3052 allele of Salmonella typhimurium.
Molecular & general genetics : MGG 1995;247(1):7-16.
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1995: Yamada M; Sedgwick B; Sofuni T; Nohmi T
Construction and characterization of mutants of Salmonella typhimurium deficient in DNA repair of O6-methylguanine.
Journal of bacteriology 1995;177(6):1511-9.
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1995: Hayashi M; Sofuni T
The need for three dose levels to detect genotoxic chemicals in in vivo rodent assays.
Mutation research 1995;327(1-2):247-51.
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1995: Suzuki T; Hayashi M; Hakura A; Asita A O; Kodama Y; Honma M; Sofuni T
Combination effects of clastogens in the mouse peripheral blood micronucleus assay.
Mutagenesis 1995;10(1):31-6.
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1994: Watanabe M; Igarashi T; Kaminuma T; Sofuni T; Nohmi T
N-hydroxyarylamine O-acetyltransferase of Salmonella typhimurium: proposal for a common catalytic mechanism of arylamine acetyltransferase enzymes.
Environmental health perspectives 1994;102 Suppl 6():83-9.
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1994: Suzuki T; Hayashi M; Sofuni T
Initial experiences and future directions for transgenic mouse mutation assays.
Mutation research 1994;307(2):489-94.
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1994: Hayashi M; Mäki-Paakkanen J; Tanabe H; Honma M; Suzuki T; Matsuoka A; Mizusawa H; Sofuni T
Isolation of micronuclei from mouse blood and fluorescence in situ hybridization with a mouse centromeric DNA probe.
Mutation research 1994;307(1):245-51.
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1994: Watanabe M; Matsuoka A; Yamazaki N; Hayashi M; Deguchi T; Nohmi T; Sofuni T
New sublines of Chinese hamster CHL stably expressing human NAT1 or NAT2 N-acetyltransferases or Salmonella typhimurium O-acetyltransferase: comparison of the sensitivities to nitroarenes and aromatic amines using the in vitro micronucleus test.
Cancer research 1994;54(7):1672-7.
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1994: Matsuoka A; Tucker J D; Hayashi M; Yamazaki N; Sofuni T
Chromosome painting analysis of X-ray-induced aberrations in human lymphocytes in vitro.
Mutagenesis 1994;9(2):151-5.
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1994: Hayashi M; Hashimoto S; Sakamoto Y; Hamada C; Sofuni T; Yoshimura I
Statistical analysis of data in mutagenicity assays: rodent micronucleus assay.
Environmental health perspectives 1994;102 Suppl 1():49-52.
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1994: Honma M; Mizusawa H; Sasaki K; Hayashi M; Ohno T; Tanaka N; Sofuni T
Demonstration by DNA fingerprint analysis of genomic instability in mouse BALB 3T3 cells during cell transformation.
Mutation research 1994;304(2):167-79.
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1993: Yamada M; Hakura A; Sofuni T; Nohmi T
New method for gene disruption in Salmonella typhimurium: construction and characterization of an ada-deletion derivative of Salmonella typhimurium TA1535.
Journal of bacteriology 1993;175(17):5539-47.
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1993: Honma M; Mitani K; Mizusawa H; Hayashi M; Sofuni T; Muramatsu M; Komonami R
A new VNTR polymorphism at locus D1S340.
Human molecular genetics 1993;2(8):1329.
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1993: Hagiwara Y; Watanabe M; Oda Y; Sofuni T; Nohmi T
Specificity and sensitivity of Salmonella typhimurium YG1041 and YG1042 strains possessing elevated levels of both nitroreductase and acetyltransferase activity.
Mutation research 1993;291(3):171-80.
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1993: Honma M; Kataoka E; Ohnishi K; Kikuno T; Hayashi M; Sofuni T; Mizusawa H
Detection of recombinational mutations in cultured human cells by Southern blot analysis with minisatellite DNA probes.
Mutation research 1993;286(2):165-72.
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1993: Suzuki T; Hayashi M; Sofuni T; Myhr B C
The concomitant detection of gene mutation and micronucleus induction by mitomycin C in vivo using lacZ transgenic mice.
Mutation research 1993;285(2):219-24.
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1993: Matsuoka A; Horikawa K; Yamazaki N; Sera N; Sofuni T; Tokiwa H
Chromosomal aberrations induced in vitro by 3,7- and 3,9-dinitrofluoranthene.
Mutation research 1993;298(4):255-9.
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1993: Watanabe M; Sofuni T; Nohmi T
Comparison of the sensitivity of Salmonella typhimurium strains YG1024 and YG1012 for detecting the mutagenicity of aromatic amines and nitroarenes.
Mutation research 1993;301(1):7-12.
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1993: Sofuni T
Japanese guidelines for mutagenicity testing. Ministry of Agriculture, Forestry and Fisheries; Ministry of Health and Welfare; Ministry of Labor.
Environmental and molecular mutagenesis 1993;21(1):2-7; discussion 46-57.
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1992: Matsuoka A; Yamazaki N; Suzuki T; Hayashi M; Sofuni T
Evaluation of the micronucleus test using a Chinese hamster cell line as an alternative to the conventional in vitro chromosomal aberration test.
Mutation research 1992;272(3):223-36.
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1992: Nohmi T; Yamada M; Watanabe M; Murayama S Y; Sofuni T
Roles of Salmonella typhimurium umuDC and samAB in UV mutagenesis and UV sensitivity.
Journal of bacteriology 1992;174(21):6948-55.
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1992: Honma M; Mitani K; Mizusawa H; Sofuni T; Muramatsu M; Kominami R
A new VNTR-type RFLP probe (ChdTC-114) on chromosome 20p (D20S72).
Human molecular genetics 1992;1(7):554.
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1992: Honma M; Mitani K; Mizusawa H; Sofuni T; Muramatsu M; Kominami R
A new VNTR-type RFLP probe (lambda TM-18) on chromosome 1 (D1S157).
Human molecular genetics 1992;1(7):554.
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1992: Honma M; Mitani K; Mizusawa H; Sofuni T; Muramatsu M; Kominami R
A new VNTR-type RFLP probe (ChdTC-15) on chromosome 12 (D12S65).
Human molecular genetics 1992;1(7):555.
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1992: Yamada M; Sofuni T; Nohmi T
Preferential induction of AT-TA transversion, but not deletions, by chlorambucil at the hisG428 site of Salmonella typhimurium TA102.
Mutation research 1992;283(1):29-33.
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1992: Kataoka E; Honma M; Ohnishi K; Sofuni T; Mizusawa H
Application of highly polymorphic DNA markers to the identification of HeLa cell sublines.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1992;28A(7-8):553-6.
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1992: Hayashi M; Norppa H; Sofuni T; Ishidate M
Flow cytometric micronucleus test with mouse peripheral erythrocytes.
Mutagenesis 1992;7(4):257-64.
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1992: Hayashi M; Norppa H; Sofuni T; Ishidate M
Mouse bone marrow micronucleus test using flow cytometry.
Mutagenesis 1992;7(4):251-6.
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1992: Watanabe M; Sofuni T; Nohmi T
Involvement of Cys69 residue in the catalytic mechanism of N-hydroxyarylamine O-acetyltransferase of Salmonella typhimurium. Sequence similarity at the amino acid level suggests a common catalytic mechanism of acetyltransferase for S. typhimurium and higher organisms.
The Journal of biological chemistry 1992;267(12):8429-36.
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1992: Hayashi M; Kodama Y; Awogi T; Suzuki T; Asita A O; Sofuni T
The micronucleus assay using peripheral blood reticulocytes from mitomycin C- and cyclophosphamide-treated rats.
Mutation research 1992;278(2-3):209-13.
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1992: Suzuki T; Tamai K; Kodama Y; Asita A O; Matsuoka A; Sofuni T; Kurita M; Ohtsuki H; Hiwatashi T; Hayashi M
Micronucleus induction in mouse peripheral reticulocytes by 7,12-dimethylbenz[a]anthracene.
Mutation research 1992;278(2-3):169-73.
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1992: Asita A O; Hayashi M; Kodama Y; Matsuoka A; Suzuki T; Sofuni T
Micronucleated reticulocyte induction by ethylating agents in mice.
Mutation research 1992;271(1):29-37.
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1991: Nakadate M; Hayashi M; Sofuni T; Kamata E; Aida Y; Osada T; Ishibe T; Sakamura Y; Ishidate M
The expert system for toxicity prediction of chemicals based on structure-activity relationship.
Environmental health perspectives 1991;96():77-9.
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1991: Hayashi M; Nakadate M; Osada T; Ishibe T; Tanaka S; Maekawa A; Sofuni T; Nakata Y; Kanoh N; Hashiba S
A fact database for toxicological data at the National Institute of Hygienic Sciences, Japan.
Environmental health perspectives 1991;96():57-60.
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1991: Sawada M; Sofuni T; Ishidate M
Decreased clastogenicity of dinitropyrenes in Chinese hamster lung (CHL) subclone cells with low NADPH-cytochrome P-450 reductase activity.
Mutation research 1991;264(1):37-41.
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1991: Sawada M; Sofuni T; Ishidate M
Isolation of a menadione-resistant subclone from Chinese hamster lung (CHL) cells in culture.
Mutation research 1991;249(1):7-17.
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1991: Hayashi M; Sofuni T; Morita T
Simulation study of the effects of multiple treatments in the mouse bone marrow micronucleus test.
Mutation research 1991;252(3):281-7.
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1991: Hakura A; Morimoto K; Sofuni T; Nohmi T
Cloning and characterization of the Salmonella typhimurium ada gene, which encodes O6-methylguanine-DNA methyltransferase.
Journal of bacteriology 1991;173(12):3663-72.
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1991: Nohmi T; Hakura A; Nakai Y; Watanabe M; Murayama S Y; Sofuni T
Salmonella typhimurium has two homologous but different umuDC operons: cloning of a new umuDC-like operon (samAB) present in a 60-megadalton cryptic plasmid of S. typhimurium.
Journal of bacteriology 1991;173(3):1051-63.
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1991: Matsuoka A; Sofuni T; Miyata N; Ishidate M
Clastogenicity of 1-nitropyrene, dinitropyrenes, fluorene and mononitrofluorenes in cultured Chinese hamster cells.
Mutation research 1991;259(1):103-10.
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1990: Hayashi M; Morita T; Kodama Y; Sofuni T; Ishidate M
The micronucleus assay with mouse peripheral blood reticulocytes using acridine orange-coated slides.
Mutation research 1990;245(4):245-9.
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1990: Sofuni T; Matsuoka A; Sawada M; Ishidate M; Zeiger E; Shelby M D
A comparison of chromosome aberration induction by 25 compounds tested by two Chinese hamster cell (CHL and CHO) systems in culture.
Mutation research 1990;241(2):175-213.
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1990: Matsuoka A; Matsui M; Miyata N; Sofuni T; Ishidate M
Mutagenicity of 3-tert-butyl-4-hydroxyanisole (BHA) and its metabolites in short-term tests in vitro.
Mutation research 1990;241(2):125-32.
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1988: Hayashi M; Kishi M; Sofuni T; Ishidate M
Micronucleus tests in mice on 39 food additives and eight miscellaneous chemicals.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1988;26(6):487-500.
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