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Eric Boerwinkle

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Adrienne Tin; Brad C Astor; Eric Boerwinkle; Josef Coresh; Ron C Hoogeveen; Wen Hong Linda Kao
Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin.
Wolfgang Lieb; Christina Loley; Ruth McPherson; Christopher P Nelson; Christopher Newton-Cheh; Michael J Pencina; Annette Peters; Muredach P Reilly; Nilesh J Samani; Heribert Schunkert; John R Thompson; Unnur Thorsteinsdottir; Ramachandran S Vasan; Andreas Ziegler; Themistocles L Assimes; Eric Boerwinkle; Jeanette Erdmann; Alistair S Hall; Christian Hengstenberg; Henning Jansen; Sekar Kathiresan; Inke R König; Reijo Laaksonen
Genetic predisposition to higher blood pressure increases coronary artery disease risk.
Caitrin W McDonough; Carl J Pepine; Stephen T Turner; Taimour Y Langaee; Kent R Bailey; Amber L Beitelshees; Eric Boerwinkle; Sarah E Burbage; Arlene B Chapman; Rhonda M Cooper-DeHoff; Julio Duarte; Yan Gong; John G Gums; Julie A Johnson
Association of variants in NEDD4L with blood pressure response and adverse cardiovascular outcomes in hypertensive patients treated with thiazide diuretics.

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2013: Adrienne Tin; Brad C Astor; Eric Boerwinkle; Josef Coresh; Ron C Hoogeveen; Wen Hong Linda Kao
Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin.
Human genetics 2013;132(6):619-27.
2013: Wolfgang Lieb; Christina Loley; Ruth McPherson; Christopher P Nelson; Christopher Newton-Cheh; Michael J Pencina; Annette Peters; Muredach P Reilly; Nilesh J Samani; Heribert Schunkert; John R Thompson; Unnur Thorsteinsdottir; Ramachandran S Vasan; Andreas Ziegler; Themistocles L Assimes; Eric Boerwinkle; Jeanette Erdmann; Alistair S Hall; Christian Hengstenberg; Henning Jansen; Sekar Kathiresan; Inke R König; Reijo Laaksonen
Genetic predisposition to higher blood pressure increases coronary artery disease risk.
Hypertension 2013;61(5):995-1001.
2013: Caitrin W McDonough; Carl J Pepine; Stephen T Turner; Taimour Y Langaee; Kent R Bailey; Amber L Beitelshees; Eric Boerwinkle; Sarah E Burbage; Arlene B Chapman; Rhonda M Cooper-DeHoff; Julio Duarte; Yan Gong; John G Gums; Julie A Johnson
Association of variants in NEDD4L with blood pressure response and adverse cardiovascular outcomes in hypertensive patients treated with thiazide diuretics.
Journal of hypertension 2013;31(4):698-704.
2013: Andrea E Cassidy-Bushrow; Sharon L R Kardia; Albert M Levin; Xihong Lin; Lawrence F Bielak; Eric Boerwinkle; Patrick F Sheedy; Stephen T Turner; Patricia A Peyser
Matrix gla protein gene polymorphism is associated with increased coronary artery calcification progression.
Arteriosclerosis, thrombosis, and vascular biology 2013;33(3):645-51.
2013: Andrew D Johnson; Alanna Morrison; Christopher Newton-Cheh; Eric Boerwinkle; L Adrienne Cupples; Caroline S Fox; Jane E Freedman; Udo Hoffmann; Yi-Hsiang Hsu; Shih-Jen Hwang; Gina M Peloso; Bruce M Psaty; Ian S Rogers; George Thanassoulis; Arend Voorman; Christopher J O'Donnell
Resequencing and clinical associations of the 9p21.3 region: a comprehensive investigation in the Framingham heart study.
Circulation 2013;127(7):799-810.
2013: Bing Yu; Christie M Ballantyne; Maja Barbalic; Eric Boerwinkle; Ariel Brautbar; Christopher R deFilippi; Susan R Heckbert; Ron C Hoogeveen; Sekar Kathiresan; Thomas H Mosley; Vijay Nambi; Christopher J O'Donnell; Bruce M Psaty; Ken Rice; Jerome I Rotter; Weihong Tang
Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies.
Circulation. Cardiovascular genetics 2013;6(1):82-8.
2013: Khanh-Dung H Nguyen; Vasyl Pihur; Ankit Rakha; Eric Boerwinkle; Richard S Cooper; Josef Coresh; Georg Benedikt Ehret; Barry I Freedman; Santhi Ganesh; Steven C Hunt; WEN KAO; Alanna C Morrison; Aravinda Chakravarti
Effects of rare and common blood pressure gene variants on essential hypertension: results from the Family Blood Pressure Program, CLUE, and Atherosclerosis Risk in Communities studies.
Circulation research 2013;112(2):318-26.
2013: High Seng Chai; Arlene B Chapman; Eric Boerwinkle
Response to genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.
Hypertension 2013;61(1):e6.
2013: MyPhuong T Le; Maximilian T Lobmeyer; Stephen T Turner; Zhiying Wang; Eric Boerwinkle; Marcus Campbell; Arlene B Chapman; Jing Cheng; Yan Gong; John G Gums; Richard J Johnson; Julie A Johnson
Impact of genetic polymorphisms of SLC2A2, SLC2A5, and KHK on metabolic phenotypes in hypertensive individuals.
PloS one 2013;8(1):e52062.
2013: Jan Bressler; Ellen W Demerath; Myriam Fornage; David S Knopman; Keri L Monda; Thomas H Mosley; Kari E North; Alan Penman; Eric Boerwinkle
Fat mass and obesity gene and cognitive decline: the Atherosclerosis Risk in Communities Study.
Neurology 2013;80(1):92-9.
2013: Mohammad H Rahbar; Maureen Samms-Vaughan; Sydonnie Shakespeare-Pellington; Manouchehr Ardjomand-Hessabi; Kari Bloom; Jan Bressler; Zhongxue Chen; Megan L Grove; Gerald C Lalor; Katherine A Loveland; Deborah A Pearson; Eric Boerwinkle
Seafood consumption and blood mercury concentrations in Jamaican children with and without autism spectrum disorders.
Neurotoxicity research 2013;23(1):22-38.
2012: Yan Gong; John G Gums; Wei Hou; Kent R Bailey; Amber L Beitelshees; Eric Boerwinkle; Arlene B Chapman; Rhonda M Cooper-DeHoff; Taimour Y Langaee; Caitrin W McDonough; Stephen T Turner; Zhiying Wang; Julie A Johnson
Hypertension susceptibility loci and blood pressure response to antihypertensives: results from the pharmacogenomic evaluation of antihypertensive responses study.
Circulation. Cardiovascular genetics 2012;5(6):686-91.
2012: Fabiana Quagliarini; David M Valenzuela; Yan Wang; Rhonda Hyde; Julia Kozlitina; Andrew J Murphy; Eric Boerwinkle; Jonathan C Cohen; Nick V Grishin; Helen H Hobbs
Atypical angiopoietin-like protein that regulates ANGPTL3.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(48):19751-6.
2012: Richard B Devereux; Barbara V Howard; Dalane Kitzman; Elisa T Lee; Thomas H Mosley; Donna K Arnett; Lyle G Best; Eric Boerwinkle; Giovanni de Simone; Alan B Weder; Mary J Roman
Normal limits in relation to age, body size and gender of two-dimensional echocardiographic aortic root dimensions in persons ≥15 years of age.
The American journal of cardiology 2012;110(8):1189-94.
2012: Alexander G Vandell; Taimour Y Langaee; Stephen B Liggett; Maximilian T Lobmeyer; Carl J Pepine; Stephen T Turner; Kent R Bailey; Amber L Beitelshees; Eric Boerwinkle; Arlene B Chapman; Rhonda M Cooper-DeHoff; Brian E Gawronski; Yan Gong; John G Gums; Julie A Johnson
G protein receptor kinase 4 polymorphisms: β-blocker pharmacogenetics and treatment-related outcomes in hypertension.
Hypertension 2012;60(4):957-64.
2012: Aaron R Folsom; Vijay Nambi; James S Pankow; Weihong Tang; Kazumasa Yamagishi; Kian Farbakhsh; Eric Boerwinkle
Effect of 9p21 genetic variation on coronary heart disease is not modified by other risk markers. The Atherosclerosis Risk in Communities (ARIC) Study.
Atherosclerosis 2012;224(2):435-9.
2012: Priya B Shetty; Hua Tang; Bamidele Tayo; Jeffery H Young; Xiaofeng Zhu; Eric Boerwinkle; Richard S Cooper; Ervin R Fox; Craig L Hanis; Alanna C Morrison; Dabeeru C Rao; Neil J Risch
Variants in CXADR and F2RL1 are associated with blood pressure and obesity in African-Americans in regions identified through admixture mapping.
Journal of hypertension 2012;30(10):1970-6.
2012: Mohammad H Rahbar; Maureen Samms-Vaughan; Sydonnie Shakespeare-Pellington; Julie Wirth; Jan Bressler; Zhongxue Chen; Aisha S Dickerson; Megan L Grove; Katherine A Loveland; Deborah A Pearson; Manouchehr Ardjomand-Hessabi; Kari Bloom; Eric Boerwinkle
The role of drinking water sources, consumption of vegetables and seafood in relation to blood arsenic concentrations of Jamaican children with and without Autism Spectrum Disorders.
The Science of the total environment 2012;433():362-70.
2012: Charleston W K Chiang; L Adrienne Cupples; Ellen W Demerath; Nora Franceschini; Eric Boerwinkle; Neal W Jorgensen; Brendan J Keating; Leslie A Lange; Guillaume Lettre; Ching-Ti Liu; Joanne M Murabito; Nora L Nock; Kari E North; George J Papanicolaou; Alex P Reiner; Jerome I Rotter; Sailaja Vedantam; James G Wilson; Joel N Hirschhorn
Ultraconserved elements in the human genome: association and transmission analyses of highly constrained single-nucleotide polymorphisms.
Genetics 2012;192(1):253-66.
2012: Artur Fedorowski; Nora Franceschini; Bo Hedblad; Albert Hofman; Martin G Larson; Daniel Levy; Chunyu Liu; Francesco Mattace-Raso; Christopher Newton-Cheh; Bruce M Psaty; Kenneth M Rice; Kathryn M Rose; Jerome I Rotter; Marketa Sjögren; Andre Uitterlinden; Germaine C Verwoert; Thomas J Wang; Jacqueline Witteman; Peter Almgren; Eric Boerwinkle; Jennifer Brody; David Couper; Olle Melander
Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium.
European heart journal 2012;33(18):2331-41.
2012: Mohammad H Rahbar; Maureen Samms-Vaughan; Sydonnie Shakespeare-Pellington; Manouchehr Ardjomand-Hessabi; Compton Beecher; Kari Bloom; Jan Bressler; Zhongxue Chen; Megan L Grove; Katherine A Loveland; Deborah A Pearson; Eric Boerwinkle
Maternal and paternal age are jointly associated with childhood autism in Jamaica.
Journal of autism and developmental disorders 2012;42(9):1928-38.
2012: Hui-Qi Qu; Anne R Rentfro; Perry E Bickel; Eric Boerwinkle; Michael B Fallon; Megan L Grove; Craig L Hanis; Quan Li; Yang Lu; Joseph B McCormick; Jen-Jung Pan; Susan P Fisher-Hoch
Population-based risk factors for elevated alanine aminotransferase in a South Texas Mexican-American population.
Archives of medical research 2012;43(6):482-8.
2012: Ariel Brautbar; L Adrienne Cupples; Abbas Dehghan; Aaron R Folsom; Albert Hofman; Vijay Nambi; Julius S Ngwa; Michael J Pencina; Lisa Pompeii; Fernando Rivadeneira; André G Uitterlinden; Salim S Virani; Jacqueline C M Witteman; Christie M Ballantyne; Eric Boerwinkle
A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies.
Atherosclerosis 2012;223(2):421-6.
2012: Jacob A Tennessen; Goncalo Abecasis; Joshua M Akey; David Altshuler; Michael Bamshad; Abigail W Bigham; Eric Boerwinkle; Carlos D Bustamante; Ron Do; Wenqing Fu; Stacey Gabriel; Simon Gravel; Daniel Jordan; Goo Jun; Hyun Min Kang; Eimear E Kenny; Suzanne M Leal; Xiaoming Liu; Sean McGee; Deborah A Nickerson; Timothy D O'Connor; Mark J Rieder; Shamil Sunyaev
Evolution and functional impact of rare coding variation from deep sequencing of human exomes.
Science (New York, N.Y.) 2012;337(6090):64-9.
2012: Pritam Chanda; Alex Hartz; Man Li; Naoya Yuhki; WEN KAO; Joel S Bader; Eric Boerwinkle; Dan E Arking
Comprehensive evaluation of imputation performance in African Americans.
Journal of human genetics 2012;57(7):411-21.
2012: Michael Bamshad; Eric Boerwinkle; Mark Gerstein; Richard A Gibbs; Murat Gunel; Ada Hamosh; Richard P Lifton; James R Lupski; Shrikant Mane; Deborah A Nickerson; Jay A Shendure; David Valle
The Centers for Mendelian Genomics: a new large-scale initiative to identify the genes underlying rare Mendelian conditions.
American journal of medical genetics. Part A 2012;158A(7):1523-5.
2012: Stephen T Turner; Kent R Bailey; High Seng Chai; Arlene B Chapman; Gary L Schwartz; Eric Boerwinkle
Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.
Hypertension 2012;59(6):1204-11.
2012: Amy I Lynch; Eric Boerwinkle; Barry R Davis; John H Eckfeldt; Charles E Ford; Catherine Leiendecker-Foster; Donna K Arnett
Gene panels to help identify subgroups at high and low risk of coronary heart disease among those randomized to antihypertensive treatment: the GenHAT study.
Pharmacogenetics and genomics 2012;22(5):355-66.
2012: Vijay Nambi; Kari E North; Salim S Virani; Eric Boerwinkle; Ariel Brautbar; Lloyd Chambless; Aaron R Folsom; Nora Franeschini; Kim Lawson; Christie M Ballantyne
The 9p21 genetic variant is additive to carotid intima media thickness and plaque in improving coronary heart disease risk prediction in white participants of the Atherosclerosis Risk in Communities (ARIC) Study.
Atherosclerosis 2012;222(1):135-7.
2012: Steven M Smith; Stephen T Turner; Julie A Johnson; Kent Bailey; Amber L Beitelshees; Eric Boerwinkle; Arlene B Chapman; Rhonda M Cooper-DeHoff; Yan Gong; John G Gums
Blood pressure responses and metabolic effects of hydrochlorothiazide and atenolol.
American journal of hypertension 2012;25(3):359-65.
2012: Marco Campos; Lloyd E Chambless; Maja Barbalic; Eric Boerwinkle; Ashley Buchanan; Aaron R Folsom; Kenneth K Wu; Yang Xiao; Fuli Yu; Jing-fei Dong
Influence of single nucleotide polymorphisms in factor VIII and von Willebrand factor genes on plasma factor VIII activity: the ARIC Study.
Blood 2012;119(8):1929-34.
2012: Eric Yi Liu; Teri A Manolio; Loic Le Marchand; Tara Matise; Kari E North; Ulrike Peters; Wei Wang; Aaron K Aragaki; Eric Boerwinkle; Steven Buyske; Chris Carlson; Cara Carty; Dana C Crawford; Jeff Haessler; Lucia A Hindorff; Charles Kooperberg; Yun Li
Genotype imputation of Metabochip SNPs using a study-specific reference panel of ~4,000 haplotypes in African Americans from the Women's Health Initiative.
Genetic epidemiology 2012;36(2):107-17.
2012: Eric Boerwinkle
Translational genomics is not a spectator sport: a call to action.
Genetic epidemiology 2012;36(2):85-7.
2012: Pamela L Lutsey; James S Pankow; Laura J Rasmussen-Torvik; Derek J Smolenski; Weihong Tang; Kelly A Volcik; Alvaro Alonso; Christie M Ballantyne; Eric Boerwinkle; Josef Coresh; Aaron R Folsom
Relation of lipid gene scores to longitudinal trends in lipid levels and incidence of abnormal lipid levels among individuals of European ancestry: the Atherosclerosis Risk in Communities (ARIC) study.
Circulation. Cardiovascular genetics 2012;5(1):73-80.
2012: Salim S Virani; Eric Boerwinkle; Ariel Brautbar; Diane J Catellier; Josef Coresh; Brian C Davis; Aaron R Folsom; Ron C Hoogeveen; Joel D Morrisett; Thomas H Mosley; Vijay Nambi; ALBERT SHARRETT; Christie M Ballantyne
Associations between lipoprotein(a) levels and cardiovascular outcomes in black and white subjects: the Atherosclerosis Risk in Communities (ARIC) Study.
Circulation 2012;125(2):241-9.
2012: Xiaojing Wang; Daniel E Weeks; Robert J Weyant; Zhen Zeng; Daniel W McNeil; Sarah C Nelson; Jacqueline Noel; Deborah E Polk; Elizabeth W Pugh; John R Shaffer; Alexandre R Vieira; Ida Anjomshoaa; James Beck; Ferdouse Begum; Eric Boerwinkle; Marilyn C Cornelis; David R Crosslin; Richard Crout; Karen T Cuenco; Kimberly F Doheny; Eleanor Feingold; Frank B Hu; Cathy C Laurie; Myoung-Keun Lee; Mary L Marazita
Genome-wide association scan of dental caries in the permanent dentition.
BMC oral health 2012;12():57.
2012: Quan Li; Yang Lu; Shaper Mirza; Hui-Qi Qu; Anne R Rentfro; Eric Boerwinkle; Michael B Fallon; Susan P Fisher-Hoch; Megan L Grove; Craig L Hanis; Joseph B McCormick
PNPLA3 polymorphisms and liver aminotransferase levels in a Mexican American population.
Clinical and investigative medicine. Médecine clinique et experimentale 2012;35(4):E237-45.
2012: Anna Köttgen; Xuan Liu; Luca Rampoldi; Céline Schaeffer; Lawrence C Shimmin; Adrienne Tin; Qiong Yang; Eric Boerwinkle; Josef Coresh; James E Hixson; Shih-Jen Hwang; WEN KAO; Caroline S Fox
Association of estimated glomerular filtration rate and urinary uromodulin concentrations with rare variants identified by UMOD gene region sequencing.
PloS one 2012;7(5):e38311.
2012: Li Ma; Charles F Sing; Eric Boerwinkle; Ariel Brautbar; Andrew G Clark; Alon Keinan
Knowledge-driven analysis identifies a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations.
PLoS genetics 2012;8(5):e1002714.
2012: Kiran Musunuru; Jose M Ordovas; George J Papanicolaou; Bruce M Psaty; Christie M Ballantyne; Eric Boerwinkle; Sarah Buxbaum; L Adrienne Cupples; Myriam Fornage; Stacey B Gabriel; Nicole L Glazer; Sekar Kathiresan; Ronald M Krauss; Guillaume Lettre; Kiang Liu; Susan Redline; Stephen S Rich; Simon P R Romaine; Jerome I Rotter; Pamela J Schreiner; Herman A Taylor; Michael Y Tsai; Kelly A Volcik; James G Wilson; Daniel J Rader
Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
PloS one 2012;7(5):e36473.
2012: Xue Zhang; Eric Boerwinkle; Barry R Davis; John H Eckfeldt; Charles E Ford; Catherine Leiendecker-Foster; Amy I Lynch; Donna K Arnett
Pharmacogenetic association of NOS3 variants with cardiovascular disease in patients with hypertension: the GenHAT study.
PloS one 2012;7(3):e34217.
2012: Julio Duarte; Roger B Fillingim; Yan Gong; John G Gums; Kent R Bailey; Amber L Beitelshees; Eric Boerwinkle; Ben Burkley; Arlene B Chapman; Rhonda M Cooper-DeHoff; Bruce C Kone; Taimour Y Langaee; Stephen T Turner; Issam Zineh; Julie A Johnson
Effects of genetic variation in H3K79 methylation regulatory genes on clinical blood pressure and blood pressure response to hydrochlorothiazide.
Journal of translational medicine 2012;10():56.
2012: Ching-Yu Cheng; Josef Coresh; Selvin Elizabeth; Christopher A Haiman; Brian E Henderson; Ermeg L Akylbekova; David Altshuler; Eric Boerwinkle; frederick brancati; Nick Patterson; David Reich; Arti Tandon; Herman A Taylor; James G Wilson; Elizabeth Selvin; WEN KAO
African ancestry and its correlation to type 2 diabetes in African Americans: a genetic admixture analysis in three U.S. population cohorts.
PloS one 2012;7(3):e32840.
2012: Stephen T Turner; Amber L Beitelshees; Eric Boerwinkle; Arlene B Chapman; Rhonda M Cooper-DeHoff; John G Gums; Julie A Johnson; Gary L Schwartz; Kent R Bailey
Power to identify a genetic predictor of antihypertensive drug response using different methods to measure blood pressure response.
Journal of translational medicine 2012;10():47.
2012: Salim S Virani; James T Willerson; James M Wilson; Elayda MacArthur; Eric Boerwinkle; Ariel Brautbar; Lorraine Frazier; Megan L Grove; Vei-Vei Lee; Alanna C Morrison; Vijay Nambi; Christie M Ballantyne
Chromosome 9p21 single nucleotide polymorphisms are not associated with recurrent myocardial infarction in patients with established coronary artery disease.
Circulation journal : official journal of the Japanese Circulation Society 2012;76(4):950-6.
2012: Vijay Nambi; Eric Boerwinkle; Lloyd Chambless; Aaron R Folsom; Max He; Tom Mosley; Christie M Ballantyne
Common carotid artery intima-media thickness is as good as carotid intima-media thickness of all carotid artery segments in improving prediction of coronary heart disease risk in the Atherosclerosis Risk in Communities (ARIC) study.
European heart journal 2012;33(2):183-90.
2011: Nora Franceschini; Tiana Garrett; Philip Greenland; Jonathan Bella; Lyle G Best; Eric Boerwinkle; Ebony Bookman; Petra Bůzková; Cara Carty; Shelley A Cole; Ewa Deelman; Charles Eaton; Lucia A Hindorff; Nancy Swords Jenny; Charles Kooperberg; Dan-Yu Lin; Yi Lin; Kari E North; Bruce Psaty; Alexander P Reiner; Darin Taverna; Jens-S Vöckler; Alicia M Young; Gerardo Heiss
Association of genetic variants and incident coronary heart disease in multiethnic cohorts: the PAGE study.
Circulation. Cardiovascular genetics 2011;4(6):661-72.
2011: Jan Bressler; Eric Boerwinkle; Lawrence C Shimmin; James E Hixson
Global DNA methylation and risk of subclinical atherosclerosis in young adults: the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study.
Atherosclerosis 2011;219(2):958-62.
2011: Salim S Virani; Bruce A Wasserman; Eric Boerwinkle; Diane J Catellier; Josef Coresh; Ron C Hoogeveen; Thomas H Mosley; Vijay Nambi; James D Otvos; Lisa A Pompeii; ALBERT SHARRETT; Christie M Ballantyne
Relation of cholesterol and lipoprotein parameters with carotid artery plaque characteristics: the Atherosclerosis Risk in Communities (ARIC) carotid MRI study.
Atherosclerosis 2011;219(2):596-602.
2011: Hung N Luu; Kari North; Eric Boerwinkle; Pascal L Kingah; Kelly A Volcik
Interaction of folate intake and the paraoxonase Q192R polymorphism with risk of incident coronary heart disease and ischemic stroke: the atherosclerosis risk in communities study.
Annals of epidemiology 2011;21(11):815-23.
2011: Christy L Avery; Eric Boerwinkle; Myriam Fornage; Qianchuan He; Gerardo Heiss; Lucia A Hindorff; Charles Kooperberg; James B Meigs; Kari E North; James S Pankow; Sarah A Pendergrass; Bruce M Psaty; Marylyn D Ritchie; Jerome I Rotter; Kent D Taylor; Lynne R Wilkens; Jose L Ambite; Dan Yu Lin
A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains.
PLoS genetics 2011;7(10):e1002322.
2011: James R Lupski; John W Belmont; Eric Boerwinkle; Richard A Gibbs
Clan genomics and the complex architecture of human disease.
Cell 2011;147(1):32-43.
2011: Andrei S Rodin; Grigoriy Gogoshin; Eric Boerwinkle
Systems biology data analysis methodology in pharmacogenomics.
Pharmacogenomics 2011;12(9):1349-60.
2011: Stephen T Turner; Eric Boerwinkle; Clifford R Jack; Sharon L R Kardia; Iftikhar J Kullo; Thomas H Mosley; Andrew D Rule; Gary L Schwartz; Kent R Bailey
Risk factor profile for chronic kidney disease is similar to risk factor profile for small artery disease.
Journal of hypertension 2011;29(9):1796-801.
2011: Christian P Schaaf; Robin Varghese; Humeira Akbar; Eric Boerwinkle; Jacy Crosby; Richard A Gibbs; Alicia Hawes; Lora Lewis; Donna Muzny; Aniko Sabo; Yasunari Sakai; Huda Y Zoghbi
Oligogenic heterozygosity in individuals with high-functioning autism spectrum disorders.
Human molecular genetics 2011;20(17):3366-75.
2011: Maja Barbalic; David Couper; Charles B Eaton; Nora Franceschini; Gerardo Heiss; James E Hixson; Thomas Mosley; Alex P Reiner; Chunyuan Wu; Eric Boerwinkle
Genome-wide association analysis of incident coronary heart disease (CHD) in African Americans: a short report.
PLoS genetics 2011;7(8):e1002199.
2011: Xiaoming Liu; Xueqiu Jian; Eric Boerwinkle
dbNSFP: a lightweight database of human nonsynonymous SNPs and their functional predictions.
Human mutation 2011;32(8):894-9.
2011: Li Luo; Eric Boerwinkle; Momiao Xiong
Association studies for next-generation sequencing.
Genome research 2011;21(7):1099-108.
2011: Jian Yang; Teri A Manolio; Louis R Pasquale; Eric Boerwinkle; Neil Caporaso; Julie M Cunningham; Mariza de Andrade; Bjarke Feenstra; Eleanor Feingold; M Geoffrey Hayes; William G Hill; Maria Teresa Landi; Alvaro Alonso; Guillaume Lettre; Peng Lin; Hua Ling; William Lowe; Rasika A Mathias; Mads Melbye; Elizabeth Pugh; Marilyn C Cornelis; Bruce S Weir; Michael E Goddard; Peter M Visscher
Genome partitioning of genetic variation for complex traits using common SNPs.
Nature genetics 2011;43(6):519-25.
2011: Rebecca Bell; Eric Boerwinkle; Nisha Gokul; Megan L Grove; Stacy M Herring; Monique Monita; Peter A Doris
High-resolution identity by descent mapping uncovers the genetic basis for blood pressure differences between spontaneously hypertensive rat lines.
Circulation. Cardiovascular genetics 2011;4(3):223-31.
2011: Suzette J Bielinski; Jennifer L Hall; James S Pankow; Eric Boerwinkle; Nena Matijevic-Aleksic; Max He; Lloyd Chambless; Aaron R Folsom
Genetic variants in TLR2 and TLR4 are associated with markers of monocyte activation: the Atherosclerosis Risk in Communities MRI Study.
Human genetics 2011;129(6):655-62.
2011: Salim S Virani; Ariel Brautbar; Vei-Vei Lee; Macarthur Elayda; Shehzad Sami; Vijay Nambi; Lorraine Frazier; James M Wilson; James T Willerson; Eric Boerwinkle; Christie M Ballantyne
Usefulness of single nucleotide polymorphism in chromosome 4q25 to predict in-hospital and long-term development of atrial fibrillation and survival in patients undergoing coronary artery bypass grafting.
The American journal of cardiology 2011;107(10):1504-9.
2011: Marco Campos; Wei Sun; Fuli Yu; Maja Barbalic; Weihong Tang; Lloyd E Chambless; Kenneth K Wu; Christie Ballantyne; Aaron R Folsom; Eric Boerwinkle; Jing-fei Dong
Genetic determinants of plasma von Willebrand factor antigen levels: a target gene SNP and haplotype analysis of ARIC cohort.
Blood 2011;117(19):5224-30.
2011: Stacy M Herring; Nisha Gokul; Monique Monita; Rebecca Bell; Eric Boerwinkle; Scott Wenderfer; Michael C Braun; Peter A Doris
Immunoglobulin locus associates with serum IgG levels and albuminuria.
Journal of the American Society of Nephrology : JASN 2011;22(5):881-9.
2011: Anna M Kucharska-Newton; Keri Monda; Stephen Campbell; Patrick T Bradshaw; Lynne E Wagenknecht; Eric Boerwinkle; Bruce A Wasserman; Gerardo Heiss
Association of the platelet GPIIb/IIIa polymorphism with atherosclerotic plaque morphology: the Atherosclerosis Risk in Communities (ARIC) Study.
Atherosclerosis 2011;216(1):151-6.
2011: Justin T Saunders; Vijay Nambi; James A de Lemos; Lloyd E Chambless; Salim S Virani; Eric Boerwinkle; Ron C Hoogeveen; Xiaoxi Liu; Brad C Astor; Thomas H Mosley; Aaron R Folsom; Gerardo Heiss; Josef Coresh; Christie M Ballantyne
Cardiac troponin T measured by a highly sensitive assay predicts coronary heart disease, heart failure, and mortality in the Atherosclerosis Risk in Communities Study.
Circulation 2011;123(13):1367-76.
2011: Jeannette Simino; Gang Shi; Rezart Kume; Karen Schwander; Michael A Province; C Charles Gu; Sharon L R Kardia; Aravinda Chakravarti; Georg Benedikt Ehret; Richard A Olshen; Stephen T Turner; low-tone ho; Xiaofeng Zhu; Cashell E Jaquish; Dina Paltoo; Richard S Cooper; Alan B Weder; J David Curb; Eric Boerwinkle; Steven C Hunt; Dabeeru C Rao
Five blood pressure loci identified by an updated genome-wide linkage scan: meta-analysis of the Family Blood Pressure Program.
American journal of hypertension 2011;24(3):347-54.
2011: Julia Kozlitina; Eric Boerwinkle; Jonathan C Cohen; Helen H Hobbs
Dissociation between APOC3 variants, hepatic triglyceride content and insulin resistance.
Hepatology (Baltimore, Md.) 2011;53(2):467-74.
2011: Gang Shi; Eric Boerwinkle; Alanna C Morrison; C Charles Gu; Aravinda Chakravarti; Dabeeru C Rao
Mining gold dust under the genome wide significance level: a two-stage approach to analysis of GWAS.
Genetic epidemiology 2011;35(2):111-8.
2011: Richard Sherva; Charles E Ford; John H Eckfeldt; Barry R Davis; Eric Boerwinkle; Donna K Arnett
Pharmacogenetic effect of the stromelysin (MMP3) polymorphism on stroke risk in relation to antihypertensive treatment: the genetics of hypertension associated treatment study.
Stroke; a journal of cerebral circulation 2011;42(2):330-5.
2011: Marisa A Vineyard; Molly S Daniels; Diana L Urbauer; Michael T Deavers; Charlotte C Sun; Eric Boerwinkle; Diane C Bodurka; David M Gershenson; Jessica Crawford; Karen H Lu
Is low-grade serous ovarian cancer part of the tumor spectrum of hereditary breast and ovarian cancer?
Gynecologic oncology 2011;120(2):229-32.
2011: Salim S Virani; Vijay Nambi; Ron Hoogeveen; Bruce A Wasserman; Josef Coresh; Franklyn Gonzalez; Lloyd E Chambless; Thomas H Mosley; Eric Boerwinkle; Christie M Ballantyne
Relationship between circulating levels of RANTES (regulated on activation, normal T-cell expressed, and secreted) and carotid plaque characteristics: the Atherosclerosis Risk in Communities (ARIC) Carotid MRI Study.
European heart journal 2011;32(4):459-68.
2011: Rikki M Tanner; Eric Boerwinkle; Victoria H Brophy; Barry R Davis; John H Eckfeldt; Charles E Ford; Amy I Lynch; Donna K Arnett
Pharmacogenetic associations of MMP9 and MMP12 variants with cardiovascular disease in patients with hypertension.
PloS one 2011;6(8):e23609.
2011: Rahul C Deo; James G Wilson; Chao Xing; Kim Lawson; WEN KAO; David Reich; Arti Tandon; Ermeg Akylbekova; Nick Patterson; Thomas H Mosley; Eric Boerwinkle; Herman A Taylor
Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans.
PloS one 2011;6(1):e14581.
2011: Maximilian T Lobmeyer; Liewei Wang; Issam Zineh; Stephen T Turner; John G Gums; Arlene B Chapman; Rhonda M Cooper-DeHoff; Amber L Beitelshees; Kent R Bailey; Eric Boerwinkle; Carl J Pepine; Julie A Johnson
Polymorphisms in genes coding for GRK2 and GRK5 and response differences in antihypertensive-treated patients.
Pharmacogenetics and genomics 2011;21(1):42-9.
2011: Laura J Rasmussen-Torvik; Man Li; WEN KAO; David Couper; Eric Boerwinkle; Suzette J Bielinski; Aaron R Folsom; James S Pankow
Association of a fasting glucose genetic risk score with subclinical atherosclerosis: The Atherosclerosis Risk in Communities (ARIC) study.
Diabetes 2011;60(1):331-5.
2010: Weihong Tang; Saonli Basu; Xiaoxiao Kong; James S Pankow; Nena Aleksic; Adrian Tan; Mary Cushman; Eric Boerwinkle; Aaron R Folsom
Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study.
Blood 2010;116(23):5032-6.
2010: Kari E North; Nora Franceschini; Christy L Avery; Lisa Baird; Mariaelisa Graff; Mark Leppert; Jay H Chung; Jinghui Zhang; Craig Hanis; Eric Boerwinkle; Kelly A Volcik; Megan L Grove; Thomas H Mosley; Charles Gu; Gerardo Heiss; James S Pankow; David J Couper; Christie M Ballantyne; W H Linda Kao; Alan B Weder; Richard S Cooper; Georg Benedikt Ehret; Ashley A O'Connor; Aravinda Chakravarti; Steven C Hunt
Variation in the checkpoint kinase 2 gene is associated with type 2 diabetes in multiple populations.
Acta diabetologica 2010;47 Suppl 1():199-207.
2010: Laura J Rasmussen-Torvik; Alvaro Alonso; Man Li; WEN KAO; Anna Köttgen; Yu Yan; David Couper; Eric Boerwinkle; Suzette J Bielinski; James S Pankow
Impact of repeated measures and sample selection on genome-wide association studies of fasting glucose.
Genetic epidemiology 2010;34(7):665-73.
2010: Marguerite R Irvin; Amy I Lynch; Edmond K Kabagambe; Hemant K Tiwari; Joshua I Barzilay; John H Eckfeldt; Eric Boerwinkle; Barry R Davis; Charles E Ford; Donna K Arnett
Pharmacogenetic association of hypertension candidate genes with fasting glucose in the GenHAT Study.
Journal of hypertension 2010;28(10):2076-83.
2010: Stephen T Turner; Gary L Schwartz; Arlene B Chapman; Amber L Beitelshees; John G Gums; Rhonda M Cooper-DeHoff; Eric Boerwinkle; Julie A Johnson; Kent R Bailey
Plasma renin activity predicts blood pressure responses to beta-blocker and thiazide diuretic as monotherapy and add-on therapy for hypertension.
American journal of hypertension 2010;23(9):1014-22.
2010: Jennifer A Nettleton; Nena Matijevic; Jack L Follis; Aaron R Folsom; Eric Boerwinkle
Associations between dietary patterns and flow cytometry-measured biomarkers of inflammation and cellular activation in the Atherosclerosis Risk in Communities (ARIC) Carotid Artery MRI Study.
Atherosclerosis 2010;212(1):260-7.
2010: Dale S Hardy; Deanna M Hoelscher; Corinne C Aragaki; June Stevens; Lyn M Steffen; James S Pankow; Eric Boerwinkle
Association of glycemic index and glycemic load with risk of incident coronary heart disease among Whites and African Americans with and without type 2 diabetes: the Atherosclerosis Risk in Communities study.
Annals of epidemiology 2010;20(8):610-6.
2010: Julio Duarte; Maximilian T Lobmeyer; Zhiying Wang; Arlene B Chapman; John G Gums; Taimour Y Langaee; Eric Boerwinkle; Stephen T Turner; Julie A Johnson
Lack of association between polymorphisms in STK39, a putative thiazide response gene, and blood pressure response to hydrochlorothiazide.
Pharmacogenetics and genomics 2010;20(8):516-9.
2010: Ervin R Fox; Kathy L Klos; Alan D Penman; George J Blair; Benjamin D Blossom; Donna K Arnett; Richard B Devereux; Tandaw Samdarshi; Eric Boerwinkle; Thomas H Mosley
Heritability and genetic linkage of left ventricular mass, systolic and diastolic function in hypertensive African Americans (From the GENOA Study).
American journal of hypertension 2010;23(8):870-5.
2010: Myriam Fornage; George Papanicolaou; Cora E Lewis; Eric Boerwinkle; David S Siscovick
Common INSIG2 polymorphisms are associated with age-related changes in body size and high-density lipoprotein cholesterol from young adulthood to middle age.
Metabolism: clinical and experimental 2010;59(8):1084-91.
2010: Yu Yan; Kari E North; Gerardo Heiss; Ronald Klein; Cynthia J Girman; Ethan M Lange; James S Pankow; frederick brancati; Eric Boerwinkle
Transcription factor 7-like 2 (TCF7L2) polymorphism and context-specific risk of impaired fasting glucose in African American and Caucasian adults: the atherosclerosis risk in communities (ARIC) study.
Diabetes/metabolism research and reviews 2010;26(5):371-7.
2010: Lu Qi; Marilyn C Cornelis; Peter Kraft; Kristopher J Stanya; W H Linda Kao; James S Pankow; Josée Dupuis; Jose C Florez; Caroline S Fox; Guillaume Paré; Qi Sun; Cynthia J Girman; Cathy C Laurie; Daniel B Mirel; Teri A Manolio; Daniel I Chasman; Eric Boerwinkle; Paul M Ridker; David J Hunter; James B Meigs; Chih-Hao Lee; Frank B Hu; Rob M van Dam
Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes.
Human molecular genetics 2010;19(13):2706-15.
2010: Kelly A Volcik; Christie M Ballantyne; Ron Hoogeveen; Aaron R Folsom; Eric Boerwinkle
Intercellular adhesion molecule-1 G241R polymorphism predicts risk of incident ischemic stroke: Atherosclerosis Risk in Communities study.
Stroke; a journal of cerebral circulation 2010;41(5):1038-40.
2010: John W Gaubatz; Christie M Ballantyne; Bruce A Wasserman; Max He; Lloyd E Chambless; Eric Boerwinkle; Ron C Hoogeveen
Association of circulating matrix metalloproteinases with carotid artery characteristics: the Atherosclerosis Risk in Communities Carotid MRI Study.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(5):1034-42.
2010: Kelly A Volcik; Stephen Campbell; Lloyd E Chambless; Josef Coresh; Aaron R Folsom; Thomas H Mosley; Hanyu Ni; Lynne E Wagenknecht; Bruce A Wasserman; Eric Boerwinkle
MMP2 genetic variation is associated with measures of fibrous cap thickness: The Atherosclerosis Risk in Communities Carotid MRI Study.
Atherosclerosis 2010;210(1):188-93.
2010: Vijay Nambi; Lloyd E Chambless; Aaron R Folsom; Max He; Yijuan Hu; Tom Mosley; Kelly Volcik; Eric Boerwinkle; Christie M Ballantyne
Carotid intima-media thickness and presence or absence of plaque improves prediction of coronary heart disease risk: the ARIC (Atherosclerosis Risk In Communities) study.
Journal of the American College of Cardiology 2010;55(15):1600-7.
2010: Ching-Yu Cheng; David Reich; Tien Y Wong; Ronald Klein; Barbara E K Klein; Nick Patterson; Arti Tandon; Man Li; Eric Boerwinkle; ALBERT SHARRETT; WEN KAO
Admixture mapping scans identify a locus affecting retinal vascular caliber in hypertensive African Americans: the Atherosclerosis Risk in Communities (ARIC) study.
PLoS genetics 2010;6(4):e1000908.
2010: Vesna D Garovic; Kent R Bailey; Eric Boerwinkle; Steven C Hunt; Alan B Weder; David Curb; Thomas H Mosley; Heather J Wiste; Stephen T Turner
Hypertension in pregnancy as a risk factor for cardiovascular disease later in life.
Journal of hypertension 2010;28(4):826-33.
2010: Chao Xing; Jonathan C Cohen; Eric Boerwinkle
A weighted false discovery rate control procedure reveals alleles at FOXA2 that influence fasting glucose levels.
American journal of human genetics 2010;86(3):440-6.
2010: Ching-Yu Cheng; David Reich; Josef Coresh; Eric Boerwinkle; Nick Patterson; Man Li; Kari E North; Arti Tandon; Joan E Bailey-Wilson; James G Wilson; WEN KAO
Admixture mapping of obesity-related traits in African Americans: the Atherosclerosis Risk in Communities (ARIC) Study.
Obesity (Silver Spring, Md.) 2010;18(3):563-72.
2010: Tamra E Meyer; Eric Boerwinkle; Alanna C Morrison; Kelly A Volcik; Maureen Sanderson; Ann L Coker; James S Pankow; Aaron R Folsom
Diabetes genes and prostate cancer in the Atherosclerosis Risk in Communities study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010;19(2):558-65.
2010: Pascal L Kingah; Hung N Luu; Kelly A Volcik; Alanna C Morrison; Jennifer A Nettleton; Eric Boerwinkle
Association of NOS3 Glu298Asp SNP with hypertension and possible effect modification of dietary fat intake in the ARIC study.
Hypertension research : official journal of the Japanese Society of Hypertension 2010;33(2):165-9.
2010: Anna M Kucharska-Newton; Keri Monda; Suzette J Bielinski; Eric Boerwinkle; Thomas D Rea; Wayne D Rosamond; James S Pankow; Anna Köttgen; Gerardo Heiss; Kari E North
Role of BMI in the Association of the TCF7L2 rs7903146 Variant with Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study.
Journal of obesity 2010;2010():.
2010: Mark Bi; WEN KAO; Eric Boerwinkle; Ron C Hoogeveen; Laura J Rasmussen-Torvik; Brad C Astor; Kari E North; Josef Coresh; Anna Köttgen
Association of rs780094 in GCKR with metabolic traits and incident diabetes and cardiovascular disease: the ARIC Study.
PloS one 2010;5(7):e11690.
2010: Jan Bressler; WEN KAO; James S Pankow; Eric Boerwinkle
Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study.
PloS one 2010;5(5):e10521.
2010: Yu Yan; Ronald Klein; Gerardo Heiss; Cynthia J Girman; Ethan M Lange; Barbara E Klein; Kathryn M Rose; Eric Boerwinkle; James S Pankow; frederick brancati; Christie M Ballantyne; Anna Köttgen; Kari E North
The transcription factor 7-like 2 (TCF7L2) polymorphism may be associated with focal arteriolar narrowing in Caucasians with hypertension or without diabetes: the ARIC Study.
BMC endocrine disorders 2010;10():9.
2010: Dan E Arking; Kyndaron Reinier; Wendy S Post; Jonathan Jui; Gina Hilton; Ashley O'Connor; Ronald J Prineas; Eric Boerwinkle; Bruce M Psaty; Gordon F Tomaselli; Thomas Rea; Nona Sotoodehnia; David S Siscovick; Gregory L Burke; Eduardo Marban; PETER SPOONER; Aravinda Chakravarti; Sumeet S Chugh
Genome-wide association study identifies GPC5 as a novel genetic locus protective against sudden cardiac arrest.
PloS one 2010;5(3):e9879.
2010: Amber L Beitelshees; Yan Gong; Kent R Bailey; Stephen T Turner; Arlene B Chapman; Gary L Schwartz; John G Gums; Eric Boerwinkle; Julie A Johnson
Comparison of office, ambulatory, and home blood pressure antihypertensive response to atenolol and hydrochlorthiazide.
Journal of clinical hypertension (Greenwich, Conn.) 2010;12(1):14-21.
2010: Jan Bressler; Aaron R Folsom; David J Couper; Kelly A Volcik; Eric Boerwinkle
Genetic variants identified in a European genome-wide association study that were found to predict incident coronary heart disease in the atherosclerosis risk in communities study.
American journal of epidemiology 2010;171(1):14-23.
2010: Xiaoming Liu; Yun-Xin Fu; Taylor J Maxwell; Eric Boerwinkle
Estimating population genetic parameters and comparing model goodness-of-fit using DNA sequences with error.
Genome research 2010;20(1):101-9.
2010: Rhonda M Cooper-DeHoff; Sheron Wen; Amber L Beitelshees; Issam Zineh; John G Gums; Stephen T Turner; Yan Gong; Karen Hall; Vishal Parekh; Arlene B Chapman; Eric Boerwinkle; Julie A Johnson
Impact of abdominal obesity on incidence of adverse metabolic effects associated with antihypertensive medications.
Hypertension 2010;55(1):61-8.
2009: Eric Y Yang; Vijay Nambi; Zhengzheng Tang; Salim S Virani; Eric Boerwinkle; Ron C Hoogeveen; Brad C Astor; Thomas H Mosley; Josef Coresh; Lloyd E Chambless; Christie M Ballantyne
Clinical implications of JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) in a U.S. population insights from the ARIC (Atherosclerosis Risk in Communities) study.
Journal of the American College of Cardiology 2009;54(25):2388-95.
2009: Andrei Rodin; Anatoliy Litvinenko; Kathy Klos; Alanna C Morrison; Trevor Woodage; Josef Coresh; Eric Boerwinkle
Use of wrapper algorithms coupled with a random forests classifier for variable selection in large-scale genomic association studies.
Journal of computational biology : a journal of computational molecular cell biology 2009;16(12):1705-18.
2009: Julie A Johnson; Yan Gong; kent bailey; Rhonda M Cooper-DeHoff; Arlene B Chapman; S T Turner; G L Schwartz; K Campbell; S Schmidt; Amber L Beitelshees; Eric Boerwinkle; John G Gums
Hydrochlorothiazide and atenolol combination antihypertensive therapy: effects of drug initiation order.
Clinical pharmacology and therapeutics 2009;86(5):533-9.
2009: Steven M Smith; Shawn D Anderson; Sheron Wen; Yan Gong; Stephen T Turner; Rhonda M Cooper-DeHoff; Gary L Schwartz; Kent Bailey; Arlene B Chapman; Karen L Hall; Hua Feng; Eric Boerwinkle; Julie A Johnson; John G Gums
Lack of correlation between thiazide-induced hyperglycemia and hypokalemia: subgroup analysis of results from the pharmacogenomic evaluation of antihypertensive responses (PEAR) study.
Pharmacotherapy 2009;29(10):1157-65.
2009: Lorraine Frazier; William K Vaughn; James T Willerson; Christie M Ballantyne; Eric Boerwinkle
Inflammatory protein levels and depression screening after coronary stenting predict major adverse coronary events.
Biological research for nursing 2009;11(2):163-73.
2009: Maja Barbalic; Gary L Schwartz; Arlene B Chapman; Stephen T Turner; Eric Boerwinkle
Kininogen gene (KNG) variation has a consistent effect on aldosterone response to antihypertensive drug therapy: the GERA study.
Physiological genomics 2009;39(1):56-60.
2009: Alanna M Chamberlain; Pamela J Schreiner; Myriam Fornage; Catherine Loria; David Siscovick; Eric Boerwinkle
Ala54Thr polymorphism of the fatty acid binding protein 2 gene and saturated fat intake in relation to lipid levels and insulin resistance: the Coronary Artery Risk Development in Young Adults (CARDIA) study.
Metabolism: clinical and experimental 2009;58(9):1222-8.
2009: Chiang-Ching Huang; Myriam Fornage; Donald M Lloyd-Jones; Gina S Wei; Eric Boerwinkle; Kiang Liu
Longitudinal association of PCSK9 sequence variations with low-density lipoprotein cholesterol levels: the Coronary Artery Risk Development in Young Adults Study.
Circulation. Cardiovascular genetics 2009;2(4):354-61.
2009: Andrew D Rule; Brooke L Fridley; Steven C Hunt; Yan Asmann; Eric Boerwinkle; James S Pankow; Thomas H Mosley; Stephen T Turner
Genome-wide linkage analysis for uric acid in families enriched for hypertension.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(8):2414-20.
2009: Tibor Fulop; Andrew D Rule; Darren W Schmidt; Heather J Wiste; Kent R Bailey; Iftikhar J Kullo; Gary L Schwartz; Thomas H Mosley; Eric Boerwinkle; Stephen T Turner
C-reactive Protein among Community-Dwelling Hypertensives on Single-agent Antihypertensive Treatment.
Journal of the American Society of Hypertension : JASH 2009;3(4):260-6.
2009: Lynne Wagenknecht; Bruce A Wasserman; Lloyd E Chambless; Josef Coresh; Aaron Folsom; Thomas Mosley; Christie Ballantyne; ALBERT SHARRETT; Eric Boerwinkle
Correlates of carotid plaque presence and composition as measured by MRI: the Atherosclerosis Risk in Communities Study.
Circulation. Cardiovascular imaging 2009;2(4):314-22.
2009: Stephen T Turner; Myriam Fornage; Clifford R Jack; Thomas H Mosley; David S. Knopman; Sharon L R Kardia; Eric Boerwinkle; Mariza de Andrade
Genomic susceptibility Loci for brain atrophy, ventricular volume, and leukoaraiosis in hypertensive sibships.
Archives of neurology 2009;66(7):847-57.
2009: Dov Shiffman; Daniel I Chasman; Christie M Ballantyne; Vijay Nambi; James J Devlin; Eric Boerwinkle
Coronary heart disease risk, aspirin use, and apolipoprotein(a) 4399Met allele in the Atherosclerosis Risk in Communities (ARIC) study.
Thrombosis and haemostasis 2009;102(1):179-80.
2009: Janet E Fulton; Shifan Dai; Jo Anne Grunbaum; Eric Boerwinkle; Darwin R Labarthe
Effects of apolipoprotein E genotype on blood cholesterol in adolescent girls.
American journal of preventive medicine 2009;37(1 Suppl):S78-85.
2009: Xiaoming Liu; Taylor J Maxwell; Eric Boerwinkle; Yun-Xin Fu
Inferring population mutation rate and sequencing error rate using the SNP frequency spectrum in a sample of DNA sequences.
Molecular biology and evolution 2009;26(7):1479-90.
2009: Aaron R Folsom; Nena Aleksic; Antonio Sanhueza; Eric Boerwinkle
Risk factor correlates of platelet and leukocyte markers assessed by flow cytometry in a population-based sample.
Atherosclerosis 2009;205(1):272-8.
2009: Owen Woodward; Anna Köttgen; Josef Coresh; Eric Boerwinkle; William B Guggino; Michael Köttgen
Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(25):10338-42.
2009: Ariel Brautbar; Christie M Ballantyne; Kim Lawson; Vijay Nambi; Lloyd E Chambless; Aaron R Folsom; James T Willerson; Eric Boerwinkle
Impact of adding a single allele in the 9p21 locus to traditional risk factors on reclassification of coronary heart disease risk and implications for lipid-modifying therapy in the Atherosclerosis Risk in Communities study.
Circulation. Cardiovascular genetics 2009;2(3):279-85.
2009: Kelly A Volcik; Diane J Catellier; Aaron R Folsom; Nena Matijevic; Bruce A Wasserman; Eric Boerwinkle
SELP and SELPLG genetic variation is associated with cell surface measures of SELP and SELPLG: the Atherosclerosis Risk in Communities Carotid MRI Study.
Clinical chemistry 2009;55(6):1076-82.
2009: Amy I Lynch; Eric Boerwinkle; Barry R Davis; Charles E Ford; John H Eckfeldt; Catherine Leiendecker-Foster; Donna K Arnett
Antihypertensive pharmacogenetic effect of fibrinogen-beta variant -455G>A on cardiovascular disease, end-stage renal disease, and mortality: the GenHAT study.
Pharmacogenetics and genomics 2009;19(6):415-21.
2009: Analabha Basu; Hua Tang; Cora E Lewis; Kari E North; J David Curb; Thomas Quertermous; Thomas H Mosley; Eric Boerwinkle; Xiaofeng Zhu; Neil J Risch
Admixture mapping of quantitative trait loci for blood lipids in African-Americans.
Human molecular genetics 2009;18(11):2091-8.
2009: Anke Hilse Maitland-van der Zee; Bas J M Peters; Amy I Lynch; Eric Boerwinkle; Donna K Arnett; Suzanne Cheng; Barry R Davis; Catherine Leiendecker-Foster; Charles E Ford; John H Eckfeldt
The effect of nine common polymorphisms in coagulation factor genes (F2, F5, F7, F12 and F13 ) on the effectiveness of statins: the GenHAT study.
Pharmacogenetics and genomics 2009;19(5):338-44.
2009: Kazumasa Yamagishi; Aaron R Folsom; Wayne D Rosamond; Eric Boerwinkle
A genetic variant on chromosome 9p21 and incident heart failure in the ARIC study.
European heart journal 2009;30(10):1222-8.
2009: Nora Franceschini; Kari E North; Donna K Arnett; James S Pankow; Jay H Chung; Lisa Baird; Mark F Leppert; John H Eckfeldt; Eric Boerwinkle; C Charles Gu; Cora E Lewis; Richard H Myers; Stephen T Turner; Alan B Weder; WEN KAO; Thomas H Mosley; Aravinda Chakravarti; Holly Kramer; Jinghui Zhang; Steven C Hunt
The association of cell cycle checkpoint 2 variants and kidney function: findings of the Family Blood Pressure Program and the Atherosclerosis Risk In Communities study.
American journal of hypertension 2009;22(5):552-8.
2009: Renata I Dmitrieva; Cruz A Hinojos; Megan L Grove; Rebecca J Bell; Eric Boerwinkle; Myriam Fornage; Peter A Doris
Genome-wide identification of allelic expression in hypertensive rats.
Circulation. Cardiovascular genetics 2009;2(2):106-15.
2009: May Montasser; Lawrence C Shimmin; Craig L Hanis; Eric Boerwinkle; James E Hixson
Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans.
Journal of hypertension 2009;27(3):491-501.
2009: Julie A Johnson; Eric Boerwinkle; Issam Zineh; Arlene B Chapman; Kent Bailey; Rhonda M Cooper-DeHoff; John G Gums; R Whit Curry; Yan Gong; Amber L Beitelshees; Gary Schwartz; Stephen T Turner
Pharmacogenomics of antihypertensive drugs: rationale and design of the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) study.
American heart journal 2009;157(3):442-9.
2009: Jennifer A Nettleton; Kelly A Volcik; Ron C Hoogeveen; Eric Boerwinkle
Carbohydrate intake modifies associations between ANGPTL4[E40K] genotype and HDL-cholesterol concentrations in White men from the Atherosclerosis Risk in Communities (ARIC) study.
Atherosclerosis 2009;203(1):214-20.
2009: WEN KAO; Dan E Arking; Wendy S Post; Thomas D Rea; Nona Sotoodehnia; Ronald J Prineas; Bryan Bishe; Betty Q Doan; Eric Boerwinkle; Bruce M Psaty; Gordon F Tomaselli; Josef Coresh; David S Siscovick; Eduardo Marban; PETER SPOONER; Gregory L Burke; Aravinda Chakravarti
Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations.
Circulation 2009;119(7):940-51.
2009: Bruce M Psaty; Christopher J O'Donnell; Vilmundur Gudnason; Kathryn L Lunetta; Aaron R Folsom; Jerome I Rotter; André G Uitterlinden; Tamara B Harris; Jacqueline C M Witteman; Eric Boerwinkle
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts.
Circulation. Cardiovascular genetics 2009;2(1):73-80.
2009: Vijay Nambi; Ron C Hoogeveen; Lloyd E Chambless; Yijuan Hu; Heejung Bang; Josef Coresh; Hanyu Ni; Eric Boerwinkle; Thomas Mosley; ALBERT SHARRETT; Aaron R Folsom; Christie M Ballantyne
Lipoprotein-associated phospholipase A2 and high-sensitivity C-reactive protein improve the stratification of ischemic stroke risk in the Atherosclerosis Risk in Communities (ARIC) study.
Stroke; a journal of cerebral circulation 2009;40(2):376-81.
2009: Tamra E Meyer; Dov Shiffman; Alanna C Morrison; Charles M Rowland; Judy Z Louie; Lance A Bare; David A Ross; Andre R Arellano; Daniel I Chasman; Paul M Ridker; James S Pankow; Josef Coresh; Mary J Malloy; John P Kane; Stephen G Ellis; James J Devlin; Eric Boerwinkle
GOSR2 Lys67Arg is associated with hypertension in whites.
American journal of hypertension 2009;22(2):163-8.
2009: Jan Bressler; Myriam Fornage; Craig L Hanis; WEN KAO; Cora E Lewis; Ruth McPherson; Robert Dent; Thomas H Mosley; Len A Pennacchio; Eric Boerwinkle
The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts.
BMC medical genetics 2009;10():56.
2009: David Reich; Michael A Nalls; WEN KAO; Ermeg L Akylbekova; Arti Tandon; Nick Patterson; James C Mullikin; Wen-Chi Hsueh; Ching-Yu Cheng; Josef Coresh; Eric Boerwinkle; Man Li; Alicja Waliszewska; Julie Neubauer; Rongling Li; Tennille S Leak; Lynette Ekunwe; Joe C Files; Cheryl L Hardy; Joseph Zmuda; Herman A Taylor; Elad Ziv; Tamara B Harris; James G Wilson
Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene.
PLoS genetics 2009;5(1):e1000360.
2009: Dan E Arking; Amit Khera; Chao Xing; WEN KAO; Wendy S Post; Eric Boerwinkle; Aravinda Chakravarti
Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population.
PloS one 2009;4(1):e4333.
2009: Stefano Romeo; Wu Yin; Julia Kozlitina; Len A Pennacchio; Eric Boerwinkle; Helen H Hobbs; Jonathan C Cohen
Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans.
The Journal of clinical investigation 2009;119(1):70-9.
2009: Yu Yan; Kari E North; Christie M Ballantyne; frederick brancati; Lloyd E Chambless; Nora Franceschini; Gerardo Heiss; Anna Köttgen; James S Pankow; Elizabeth Selvin; Suzanne L West; Eric Boerwinkle
Transcription factor 7-like 2 (TCF7L2) polymorphism and context-specific risk of type 2 diabetes in African American and Caucasian adults: the Atherosclerosis Risk in Communities study.
Diabetes 2009;58(1):285-9.
2009: Charles C Chung; Lawrence Shimmin; Sivamani Natarajan; Craig L Hanis; Eric Boerwinkle; James E Hixson
Glucocorticoid receptor gene variant in the 3' untranslated region is associated with multiple measures of blood pressure.
The Journal of clinical endocrinology and metabolism 2009;94(1):268-76.
2009: Aaron R Folsom; James M Peacock; Eric Boerwinkle
Variation in PCSK9, low LDL cholesterol, and risk of peripheral arterial disease.
Atherosclerosis 2009;202(1):211-5.
2008: Abbas Dehghan; Anna Köttgen; Qiong Yang; Shih-Jen Hwang; WEN KAO; Fernando Rivadeneira; Eric Boerwinkle; Daniel Levy; Albert Hofman; Brad C Astor; Emelia Benjamin; C.M. Duijn; Jacqueline C Witteman; Josef Coresh; Caroline S Fox
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study.
Lancet 2008;372(9654):1953-61.
2008: Stefano Romeo; Julia Kozlitina; Chao Xing; Alexander Pertsemlidis; David Cox; Len A Pennacchio; Eric Boerwinkle; Jonathan C Cohen; Helen H Hobbs
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease.
Nature genetics 2008;40(12):1461-5.
2008: Magalie S Leduc; Lawrence C Shimmin; Kathy L E Klos; Craig L Hanis; Eric Boerwinkle; James E Hixson
Comprehensive evaluation of apolipoprotein H gene (APOH) variation identifies novel associations with measures of lipid metabolism in GENOA.
Journal of lipid research 2008;49(12):2648-56.
2008: Georg Benedikt Ehret; Alanna C Morrison; Ashley A O'Connor; Megan L Grove; Lisa Baird; Karen Schwander; Alan B Weder; Richard S Cooper; Dabeeru C Rao; Steven C Hunt; Eric Boerwinkle; Aravinda Chakravarti
Replication of the Wellcome Trust genome-wide association study of essential hypertension: the Family Blood Pressure Program.
European journal of human genetics : EJHG 2008;16(12):1507-11.
2008: Aaron R Folsom; James M Peacock; Ellen Demerath; Eric Boerwinkle
Variation in ANGPTL4 and risk of coronary heart disease: the Atherosclerosis Risk in Communities Study.
Metabolism: clinical and experimental 2008;57(11):1591-6.
2008: Jennifer A Nettleton; Kelly A Volcik; Ellen W Demerath; Eric Boerwinkle; Aaron R Folsom
Longitudinal changes in triglycerides according to ANGPTL4[E40K] genotype and longitudinal body weight change in the atherosclerosis risk in communities study.
Annals of epidemiology 2008;18(11):842-6.
2008: Anna Köttgen; Charles C Hsu; Josef Coresh; Alan R Shuldiner; Yvette Berthier-Schaad; Tejal Rami Gambhir; Michael W Smith; Eric Boerwinkle; WEN KAO
The association of podocin R229Q polymorphism with increased albuminuria or reduced estimated GFR in a large population-based sample of US adults.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2008;52(5):868-75.
2008: Marijo Bilusic; Carol Moreno Quinn; Nadia E Barreto; Michael R Tschannen; Eugenie L Harris; William K Porteous; Caryn M Thompson; Murray R Grigor; Alan B Weder; Eric Boerwinkle; Steven C Hunt; J David Curb; Howard J Jacob; Anne E Kwitek
Genetically hypertensive Brown Norway congenic rat strains suggest intermediate traits underlying genetic hypertension.
Croatian medical journal 2008;49(5):586-99.
2008: Analabha Basu; Hua Tang; Xiaofeng Zhu; C Charles Gu; Craig L Hanis; Eric Boerwinkle; Neil Risch
Genome-wide distribution of ancestry in Mexican Americans.
Human genetics 2008;124(3):207-14.
2008: Anna Köttgen; Shih-Jen Hwang; Evadnie Rampersaud; Josef Coresh; Kari E North; James S Pankow; James B Meigs; Jose C Florez; Afshin Parsa; Daniel Levy; Eric Boerwinkle; Alan R Shuldiner; Caroline S Fox; WEN KAO
TCF7L2 variants associate with CKD progression and renal function in population-based cohorts.
Journal of the American Society of Nephrology : JASN 2008;19(10):1989-99.
2008: Alanna M Chamberlain; Aaron R Folsom; Pamela J Schreiner; Eric Boerwinkle; Christie M Ballantyne
Low-density lipoprotein and high-density lipoprotein cholesterol levels in relation to genetic polymorphisms and menopausal status: the Atherosclerosis Risk in Communities (ARIC) Study.
Atherosclerosis 2008;200(2):322-8.
2008: Suzette J Bielinski; James S Pankow; Eric Boerwinkle; Molly S Bray; WEN KAO; Aaron R Folsom
Lack of association between uncoupling protein-2 Ala55Val polymorphism and incident diabetes in the atherosclerosis risk in communities study.
Acta diabetologica 2008;45(3):179-82.
2008: Anke Hilse Maitland-van der Zee; Amy Lynch; Eric Boerwinkle; Donna K Arnett; Barry R Davis; Catherine Leiendecker-Foster; Charles E Ford; John H Eckfeldt
Interactions between the single nucleotide polymorphisms in the homocysteine pathway (MTHFR 677C>T, MTHFR 1298 A>C, and CBSins) and the efficacy of HMG-CoA reductase inhibitors in preventing cardiovascular disease in high-risk patients of hypertension: the GenHAT study.
Pharmacogenetics and genomics 2008;18(8):651-6.
2008: Stephen T Turner; kent bailey; Brooke L Fridley; Arlene B Chapman; Gary L Schwartz; High Seng Chai; Hugues Sicotte; Jean-Pierre Kocher; Andréi S Rodin; Eric Boerwinkle
Genomic association analysis suggests chromosome 12 locus influencing antihypertensive response to thiazide diuretic.
Hypertension 2008;52(2):359-65.
2008: Azad R Bhuiyan; Wei Chen; Sathanur R Srinivasan; Janet C Rice; Nancy B Mock; Rong Tang; M Gene Bond; Eric Boerwinkle; Gerald S Berenson
Interaction of G-protein beta3 subunit and nitric oxide synthase gene polymorphisms on carotid artery intima-media thickness in young adults: the Bogalusa Heart Study.
American journal of hypertension 2008;21(8):917-21.
2008: Diane J Catellier; Nena Aleksic; Aaron R Folsom; Eric Boerwinkle
Atherosclerosis Risk in Communities (ARIC) Carotid MRI flow cytometry study of monocyte and platelet markers: intraindividual variability and reliability.
Clinical chemistry 2008;54(8):1363-71.
2008: Kathy Klos; Eric Boerwinkle; RE Ferrell; Stephen T Turner; Alanna C Morrison
ESR1 polymorphism is associated with plasma lipid and apolipoprotein levels in Caucasians of the Rochester Family Heart Study.
Journal of lipid research 2008;49(8):1701-6.
2008: James S Pankow; Eric Boerwinkle; Paul C Adams; Eliseo Guallar; Catherine Leiendecker-Foster; Jason Rogowski; John H Eckfeldt
HFE C282Y homozygotes have reduced low-density lipoprotein cholesterol: the Atherosclerosis Risk in Communities (ARIC) Study.
Translational research : the journal of laboratory and clinical medicine 2008;152(1):3-10.
2008: Kathy Klos; Lawrence Shimmin; Christie Ballantyne; Eric Boerwinkle; Andrew Clark; Josef Coresh; Craig L Hanis; Kiang Liu; Scott Sayre; James E Hixson
APOE/C1/C4/C2 hepatic control region polymorphism influences plasma apoE and LDL cholesterol levels.
Human molecular genetics 2008;17(13):2039-46.
2008: Kelly A Volcik; Jennifer A Nettleton; Christie M Ballantyne; Eric Boerwinkle
Peroxisome proliferator-activated receptor [alpha] genetic variation interacts with n-6 and long-chain n-3 fatty acid intake to affect total cholesterol and LDL-cholesterol concentrations in the Atherosclerosis Risk in Communities Study.
The American journal of clinical nutrition 2008;87(6):1926-31.
2008: Renata I Dmitrieva; Cruz A Hinojos; Eric Boerwinkle; Michael C Braun; Myriam Fornage; Peter A Doris
Hepatocyte nuclear factor 1 and hypertensive nephropathy.
Hypertension 2008;51(6):1583-9.
2008: Suzette J Bielinski; James S Pankow; Aaron R Folsom; Kari E North; Eric Boerwinkle
TCF7L2 single nucleotide polymorphisms, cardiovascular disease and all-cause mortality: the Atherosclerosis Risk in Communities (ARIC) study.
Diabetologia 2008;51(6):968-70.
2008: Themistocles L Assimes; Joshua W Knowles; James Priest; Analabha Basu; Kelly A Volcik; Audrey Southwick; Holly K Tabor; Jaana Hartiala; Hooman Allayee; Megan L Grove; Raymond Tabibiazar; Stephen Sidney; Stephen P Fortmann; Alan Go; Mark Hlatky; Carlos Iribarren; Eric Boerwinkle; Richard H Myers; Neil Risch; Thomas Quertermous
Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease.
Human genetics 2008;123(4):399-408.
2008: Kelly A Volcik; Christie M Ballantyne; Michael C Braun; Josef Coresh; Thomas H Mosley; Eric Boerwinkle
Association of the complement factor H Y402H polymorphism with cardiovascular disease is dependent upon hypertension status: The ARIC study.
American journal of hypertension 2008;21(5):533-8.
2008: Yan V Sun; Lawrence F Bielak; Patricia A Peyser; Stephen T Turner; Patrick F Sheedy; Eric Boerwinkle; Sharon L R Kardia
Application of machine learning algorithms to predict coronary artery calcification with a sibship-based design.
Genetic epidemiology 2008;32(4):350-60.
2008: Aaron R Folsom; James S Pankow; James M Peacock; Suzette J Bielinski; Gerardo Heiss; Eric Boerwinkle
Variation in TCF7L2 and increased risk of colon cancer: the Atherosclerosis Risk in Communities (ARIC) Study.
Diabetes care 2008;31(5):905-9.
2008: Themistocles L Assimes; Joshua W Knowles; James Priest; Analabha Basu; Astrid Borchert; Kelly A Volcik; Megan L Grove; Holly K Tabor; Audrey Southwick; Raymond Tabibiazar; Steve Sidney; Eric Boerwinkle; Alan S Go; Carlos Iribarren; Mark A Hlatky; Stephen P Fortmann; Richard Myers; Hartmut Kuhn; Neil Risch; Thomas Quertermous
A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease.
Atherosclerosis 2008;198(1):136-44.
2008: Richard Sherva; Michael B Miller; James S Pankow; Steven C Hunt; Eric Boerwinkle; TH Mosley; Alan B Weder; J David Curb; Amy Luke; Alanna C Morrison; Myriam Fornage; Donna K Arnett
A whole-genome scan for stroke or myocardial infarction in family blood pressure program families.
Stroke; a journal of cerebral circulation 2008;39(4):1115-20.
2008: Kelly A Volcik; Christie M Ballantyne; Flavio D Fuchs; ALBERT SHARRETT; Eric Boerwinkle
Relationship of alcohol consumption and type of alcoholic beverage consumed with plasma lipid levels: differences between Whites and African Americans of the ARIC study.
Annals of epidemiology 2008;18(2):101-7.
2008: Iftikhar J Kullo; M Todd Greene; Eric Boerwinkle; Jian Chu; Stephen T Turner; Sharon L R Kardia
Association of polymorphisms in NOS3 with the ankle-brachial index in hypertensive adults.
Atherosclerosis 2008;196(2):905-12.
2008: Shun Kohsaka; Kelly A Volcik; Aaron R Folsom; Kenneth K Wu; Christie M Ballantyne; James T Willerson; Eric Boerwinkle
Increased risk of incident stroke associated with the cyclooxygenase 2 (COX-2) G-765C polymorphism in African-Americans: the Atherosclerosis Risk in Communities Study.
Atherosclerosis 2008;196(2):926-30.
2008: Amy I Lynch; Eric Boerwinkle; Barry R Davis; Charles E Ford; John H Eckfeldt; Catherine Leiendecker-Foster; Donna K Arnett
Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension.
JAMA : the journal of the American Medical Association 2008;299(3):296-307.
2008: Alanna C Morrison; Lance A Bare; May M Luke; James S Pankow; Thomas H Mosley; James J Devlin; James T Willerson; Eric Boerwinkle
Single nucleotide polymorphisms associated with coronary heart disease predict incident ischemic stroke in the atherosclerosis risk in communities study.
Cerebrovascular diseases (Basel, Switzerland) 2008;26(4):420-4.
2008: Anna Köttgen; WEN KAO; Shih-Jen Hwang; Eric Boerwinkle; Qiong Yang; Daniel Levy; Emelia Benjamin; Martin G Larson; Brad C Astor; Josef Coresh; Caroline S Fox
Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies.
BMC medical genetics 2008;9():49.
2008: Sharon L R Kardia; M Todd Greene; Eric Boerwinkle; Stephen T Turner; Iftikhar J Kullo
Investigating the complex genetic architecture of ankle-brachial index, a measure of peripheral arterial disease, in non-Hispanic whites.
BMC medical genomics 2008;1():16.
2008: Joshua W Knowles; Themistocles L Assimes; Eric Boerwinkle; Stephen P Fortmann; Alan Go; Megan L Grove; Mark Hlatky; Carlos Iribarren; Jun Li; Richard H Myers; Neil Risch; Stephen Sidney; Audrey Southwick; Kelly A Volcik; Thomas Quertermous
Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD.
BMC medical genetics 2008;9():23.
2008: Aaron R Folsom; James M Peacock; Eric Boerwinkle; Mary Cushman
beta2-adrenergic receptor polymorphism and venous thromboembolism.
Thrombosis and haemostasis 2008;99(1):240.
2008: Alanna C Morrison; Eric Boerwinkle; Stephen T Turner; Robert E Ferrell
Regional association-based fine-mapping for sodium-lithium countertransport on chromosome 10.
American journal of hypertension 2008;21(1):117-21.
2008: Vincent J Canzanello; Evelyn Baranco-Pryor; Frederic Rahbari-Oskoui; Gary L Schwartz; Eric Boerwinkle; Stephen T Turner; Arlene B Chapman
Predictors of blood pressure response to the angiotensin receptor blocker candesartan in essential hypertension.
American journal of hypertension 2008;21(1):61-6.
2007: Wei Chen; Sathanur R Srinivasan; Eric Boerwinkle; Gerald S Berenson
Beta-adrenergic receptor genes are associated with arterial stiffness in black and white adults: the Bogalusa Heart Study.
American journal of hypertension 2007;20(12):1251-7.
2007: Lawrence C Shimmin; Sivamani Natarajan; Heladio Ibarguen; May Montasser; Do-Kyun Kim; Craig L Hanis; Eric Boerwinkle; Pathik D Wadhwa; James E Hixson
Corticotropin releasing hormone (CRH) gene variation: comprehensive resequencing for variant and molecular haplotype discovery in monosomic hybrid cell lines.
DNA sequence : the journal of DNA sequencing and mapping 2007;18(6):434-44.
2007: Aaron R Folsom; James M Peacock; Eric Boerwinkle
Sequence variation in proprotein convertase subtilisin/kexin type 9 serine protease gene, low LDL cholesterol, and cancer incidence.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(11):2455-8.
2007: Aida M Andrés; andrew clark; Lawrence Shimmin; Eric Boerwinkle; Charles F Sing; James E Hixson
Understanding the accuracy of statistical haplotype inference with sequence data of known phase.
Genetic epidemiology 2007;31(7):659-71.
2007: Amy I Lynch; Donna K Arnett; Barry R Davis; Eric Boerwinkle; Charles E Ford; John H Eckfeldt; Catherine Leiendecker-Foster
Sex-specific effects of AGT-6 and ACE I/D on pulse pressure after 6 months on antihypertensive treatment: the GenHAT study.
Annals of human genetics 2007;71(Pt 6):735-45.
2007: Kelly A Volcik; Christie M Ballantyne; Josef Coresh; Aaron R Folsom; Eric Boerwinkle
Specific P-selectin and P-selectin glycoprotein ligand-1 genotypes/haplotypes are associated with risk of incident CHD and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study.
Atherosclerosis 2007;195(1):e76-82.
2007: Lance A Bare; Alanna C Morrison; Charles M Rowland; Dov Shiffman; May M Luke; Olga A Iakoubova; John P Kane; Mary J Malloy; Stephen G Ellis; James S Pankow; James T Willerson; James J Devlin; Eric Boerwinkle
Five common gene variants identify elevated genetic risk for coronary heart disease.
Genetics in medicine : official journal of the American College of Medical Genetics 2007;9(10):682-9.
2007: Azad R Bhuiyan; Wei Chen; Sathanur R Srinivasan; Janet Rice; Nancy Mock; Rong Tang; M Gene Bond; Eric Boerwinkle; Gerald S Berenson
G-6A polymorphism of angiotensinogen gene modulates the effect of blood pressure on carotid intima-media thickness. The Bogalusa Heart Study.
American journal of hypertension 2007;20(10):1073-8.
2007: Jennifer A Nettleton; Lyn M Steffen; Christie M Ballantyne; Eric Boerwinkle; Aaron R Folsom
Associations between HDL-cholesterol and polymorphisms in hepatic lipase and lipoprotein lipase genes are modified by dietary fat intake in African American and White adults.
Atherosclerosis 2007;194(2):e131-40.
2007: Azad R Bhuiyan; Wei Chen; Sathanur R Srinivasan; Janet Rice; Nancy Mock; Rong Tang; M Gene Bond; Eric Boerwinkle; Gerald S Berenson
Influence of nitric oxide synthase gene polymorphism (G894T) on carotid artery intima-media thickness in adults: the Bogalusa Heart Study.
Journal of the American Society of Hypertension : JASH 2007;1(5):362-8.
2007: D Michael Hallman; Sathanur R Srinivasan; Wei Chen; Eric Boerwinkle; Gerald S Berenson
Relation of PCSK9 mutations to serum low-density lipoprotein cholesterol in childhood and adulthood (from The Bogalusa Heart Study).
The American journal of cardiology 2007;100(1):69-72.
2007: Kelly A Volcik; Christie M Ballantyne; Henry J Pownall; ALBERT SHARRETT; Eric Boerwinkle
Interaction effects of high-density lipoprotein metabolism gene variation and alcohol consumption on coronary heart disease risk: the atherosclerosis risk in communities study.
Journal of studies on alcohol and drugs 2007;68(4):485-92.
2007: Stephen T Turner; Gary L Schwartz; Eric Boerwinkle
Personalized medicine for high blood pressure.
Hypertension 2007;50(1):1-5.
2007: Alanna C Morrison; Lance A Bare; Lloyd E Chambless; Stephen G Ellis; Mary J Malloy; John P Kane; James S Pankow; James J Devlin; James T Willerson; Eric Boerwinkle
Prediction of coronary heart disease risk using a genetic risk score: the Atherosclerosis Risk in Communities Study.
American journal of epidemiology 2007;166(1):28-35.
2007: Ruth McPherson; Alexander Pertsemlidis; Nihan Kavaslar; Alexandre Stewart; Robert Roberts; David R Cox; David Hinds; Len A Pennacchio; Anne Tybjaerg-Hansen; Aaron R Folsom; Eric Boerwinkle; Helen H Hobbs; Jonathan C Cohen
A common allele on chromosome 9 associated with coronary heart disease.
Science (New York, N.Y.) 2007;316(5830):1488-91.
2007: Donna K Arnett; Alison E Baird; Ruth A Barkley; Craig T Basson; Eric Boerwinkle; Santhi Ganesh; David M Herrington; Yuling Hong; Cashell E Jaquish; Deborah McDermott; Christopher J O'Donnell
Relevance of genetics and genomics for prevention and treatment of cardiovascular disease: a scientific statement from the American Heart Association Council on Epidemiology and Prevention, the Stroke Council, and the Functional Genomics and Translational Biology Interdisciplinary Working Group.
Circulation 2007;115(22):2878-901.
2007: C Charles Gu; Steven C Hunt; Sharon L R Kardia; Stephen T Turner; Aravinda Chakravarti; Nicholas Schork; Richard A Olshen; David Curb; Cashell E Jaquish; Eric Boerwinkle; Dabeeru C Rao
An investigation of genome-wide associations of hypertension with microsatellite markers in the family blood pressure program (FBPP).
Human genetics 2007;121(5):577-90.
2007: M L Grove; A Morrison; Aaron R Folsom; Eric Boerwinkle; Deanna M Hoelscher; Molly S Bray
Gene-environment interaction and the GNB3 gene in the Atherosclerosis Risk in Communities study.
International journal of obesity (2005) 2007;31(6):919-26.
2007: Kristin J Meyers; Thomas H Mosley; Ervin Fox; Eric Boerwinkle; Donna K Arnett; Richard B Devereux; Sharon L R Kardia
Genetic variations associated with echocardiographic left ventricular traits in hypertensive blacks.
Hypertension 2007;49(5):992-9.
2007: Jinying Zhao; Eric Boerwinkle; Momiao Xiong
An entropy-based genome-wide transmission/disequilibrium test.
Human genetics 2007;121(3-4):357-67.
2007: Hind Muallem; Kari E North; Masao Kakoki; Mary K Wojczynski; Xia Li; Megan Grove; Eric Boerwinkle; Kirk Wilhelmsen; Gerardo Heiss; Nobuyo Maeda
Quantitative effects of common genetic variations in the 3'UTR of the human LDL-receptor gene and their associations with plasma lipid levels in the Atherosclerosis Risk in Communities study.
Human genetics 2007;121(3-4):421-31.
2007: stefano romeo; Len A Pennacchio; Yunxin Fu; Eric Boerwinkle; Anne Tybjaerg-Hansen; Helen H Hobbs; Jonathan C Cohen
Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL.
Nature genetics 2007;39(4):513-6.
2007: D Michael Hallman; Eric Boerwinkle; Victor H Gonzalez; Barbara E K Klein; Ronald Klein; Craig L Hanis
A genome-wide linkage scan for diabetic retinopathy susceptibility genes in Mexican Americans with type 2 diabetes from Starr County, Texas.
Diabetes 2007;56(4):1167-73.
2007: Barry R Davis; Donna K Arnett; Eric Boerwinkle; Charles E Ford; Catherine Leiendecker-Foster; Michael B Miller; Henry Black; John H Eckfeldt
Antihypertensive therapy, the alpha-adducin polymorphism, and cardiovascular disease in high-risk hypertensive persons: the Genetics of Hypertension-Associated Treatment Study.
The pharmacogenomics journal 2007;7(2):112-22.
2007: Yen-Pei C Chang; Xin Liu; James Dae-Ok Kim; Morna A Ikeda; Marnie R Layton; Alan B Weder; Richard S Cooper; Sharon L R Kardia; Dabeeru C Rao; Steven C Hunt; Amy Luke; Eric Boerwinkle; Aravinda Chakravarti
Multiple genes for essential-hypertension susceptibility on chromosome 1q.
American journal of human genetics 2007;80(2):253-64.
2007: Wei Chen; Shengxu Li; Sathanur R Srinivasan; Eric Boerwinkle; Gerald S Berenson
A genome scan for loci influencing levels and trends of lipoprotein lipid-related traits since childhood: The Bogalusa Heart Study.
Atherosclerosis 2007;190(2):248-55.
2007: Sharon L R Kardia; Yan V Sun; Sara C Hamon; Ruth Ann Barkley; Eric Boerwinkle; Stephen T Turner
Interactions between the adducin 2 gene and antihypertensive drug therapies in determining blood pressure in people with hypertension.
BMC medical genetics 2007;8():61.
2007: Anke Hilse Maitland-van der Zee; Eric Boerwinkle; Donna K Arnett; Barry R Davis; Catherine Leiendecker-Foster; Michael B Miller; Olaf Klungel; Charles E Ford; John H Eckfeldt
Absence of an interaction between the angiotensin-converting enzyme insertion-deletion polymorphism and pravastatin on cardiovascular disease in high-risk hypertensive patients: the Genetics of Hypertension-Associated Treatment (GenHAT) study.
American heart journal 2007;153(1):54-8.
2007: Myriam Fornage; Thomas H Mosley; Clifford R Jack; Mariza de Andrade; Sharon L R Kardia; Eric Boerwinkle; Stephen T Turner
Family-based association study of matrix metalloproteinase-3 and -9 haplotypes with susceptibility to ischemic white matter injury.
Human genetics 2007;120(5):671-80.
2007: C Charles Gu; Kai Yu; Eric Boerwinkle
Measuring marker information content by the ambiguity of block boundaries observed in dense SNP data.
Annals of human genetics 2007;71(Pt 1):127-40.
2007: Qi Wei; Peter A Doris; Martin V Pollizotto; Eric Boerwinkle; David R Jacobs; David S Siscovick; Myriam Fornage
Sequence variation in the soluble epoxide hydrolase gene and subclinical coronary atherosclerosis: interaction with cigarette smoking.
Atherosclerosis 2007;190(1):26-34.
2006: D Michael Hallman; Sathanur R Srinivasan; Wei Chen; Eric Boerwinkle; Gerald S Berenson
Longitudinal analysis of haplotypes and polymorphisms of the APOA5 and APOC3 genes associated with variation in serum triglyceride levels: the Bogalusa Heart Study.
Metabolism: clinical and experimental 2006;55(12):1574-81.
2006: Craig R Lee; MJ Mosher; Kari E North; Christy L Avery; Eric Boerwinkle; Molly S Bray; Josef Coresh; David J Couper; Aaron R Folsom; Gerardo Heiss; Darryl C Zeldin
NOS3 polymorphisms, cigarette smoking, and cardiovascular disease risk: the Atherosclerosis Risk in Communities study.
Pharmacogenetics and genomics 2006;16(12):891-9.
2006: Yan V Sun; Al Levin; Eric Boerwinkle; Henry Robertson; Sharon L R Kardia
A scan statistic for identifying chromosomal patterns of SNP association.
Genetic epidemiology 2006;30(7):627-35.
2006: Lori L Boland; Aaron R Folsom; Eric Boerwinkle
Apolipoprotein E genotype and gallbladder disease risk in a large population-based cohort.
Annals of epidemiology 2006;16(10):763-9.
2006: Suzette J Bielinski; Weihong Tang; James S Pankow; Michael B Miller; Thomas H Mosley; Eric Boerwinkle; Richard A Olshen; J David Curb; Cashell E Jaquish; Dabeeru C Rao; Alan B Weder; Donna K Arnett
Genome-wide linkage scans for loci affecting total cholesterol, HDL-C, and triglycerides: the Family Blood Pressure Program.
Human genetics 2006;120(3):371-80.
2006: Bret Payseur; andrew clark; James E Hixson; Eric Boerwinkle; Charles F Sing
Contrasting multi-site genotypic distributions among discordant quantitative phenotypes: the APOA1/C3/A4/A5 gene cluster and cardiovascular disease risk factors.
Genetic epidemiology 2006;30(6):508-18.
2006: Kelly A Volcik; Ruth Ann Barkley; Richard G Hutchinson; Thomas H Mosley; Gerardo Heiss; ALBERT SHARRETT; Christie M Ballantyne; Eric Boerwinkle
Apolipoprotein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12,491 ARIC study participants.
American journal of epidemiology 2006;164(4):342-8.
2006: Kathy Klos; Charles F Sing; Eric Boerwinkle; Sara C Hamon; Thomas J Rea; Andrew Clark; Myriam Fornage; James E Hixson
Consistent effects of genes involved in reverse cholesterol transport on plasma lipid and apolipoprotein levels in CARDIA participants.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(8):1828-36.
2006: S Li; Wei Chen; Sathanur R Srinivasan; Eric Boerwinkle; Gerald S Berenson
Influence of lipoprotein lipase gene Ser447Stop and beta1-adrenergic receptor gene Arg389Gly polymorphisms and their interaction on obesity from childhood to adulthood: the Bogalusa Heart Study.
International journal of obesity (2005) 2006;30(8):1183-8.
2006: Iftikhar J Kullo; Stephen T Turner; Sharon L R Kardia; Thomas H Mosley; Eric Boerwinkle; Mariza de Andrade
A genome-wide linkage scan for ankle-brachial index in African American and non-Hispanic white subjects participating in the GENOA study.
Atherosclerosis 2006;187(2):433-8.
2006: Aaron R Folsom; Lloyd E Chambless; Christie M Ballantyne; Josef Coresh; Gerardo Heiss; Kenneth K Wu; Eric Boerwinkle; Thomas H Mosley; Paul D Sorlie; Guoqing Diao; ALBERT SHARRETT
An assessment of incremental coronary risk prediction using C-reactive protein and other novel risk markers: the atherosclerosis risk in communities study.
Archives of internal medicine 2006;166(13):1368-73.
2006: Stephen T Turner; Sharon L R Kardia; Thomas H Mosley; Andrew D Rule; Eric Boerwinkle; Mariza de Andrade
Influence of genomic loci on measures of chronic kidney disease in hypertensive sibships.
Journal of the American Society of Nephrology : JASN 2006;17(7):2048-55.
2006: Iftikhar J Kullo; Keyue Ding; Eric Boerwinkle; Stephen T Turner; Thomas H Mosley; Sharon L R Kardia; Mariza de Andrade
Novel genomic loci influencing plasma homocysteine levels.
Stroke; a journal of cerebral circulation 2006;37(7):1703-9.
2006: C M Brown; Thomas J Rea; Sara C Hamon; James E Hixson; Eric Boerwinkle; andrew clark; Charles F Sing
The contribution of individual and pairwise combinations of SNPs in the APOA1 and APOC3 genes to interindividual HDL-C variability.
Journal of molecular medicine (Berlin, Germany) 2006;84(7):561-72.
2006: Iftikhar J Kullo; Keyue Ding; Eric Boerwinkle; Stephen T Turner; Mariza de Andrade
Quantitative trait loci influencing low density lipoprotein particle size in African Americans.
Journal of lipid research 2006;47(7):1457-62.
2006: Andrew D Rule; Steven J Jacobsen; Gary L Schwartz; Thomas H Mosley; Christopher G Scott; Sharon L R Kardia; Eric Boerwinkle; Stephen T Turner
A comparison of serum creatinine-based methods for identifying chronic kidney disease in hypertensive individuals and their siblings.
American journal of hypertension 2006;19(6):608-14.
2006: Alexander P Reiner; Cara L Carty; Christopher S Carlson; J Y Wan; Mark J Rieder; J D Smith; K Rice; Myriam Fornage; Cashell E Jaquish; Dale O Williams; Russell P Tracy; C E Lewis; David S Siscovick; Eric Boerwinkle; Deborah A Nickerson
Association between patterns of nucleotide variation across the three fibrinogen genes and plasma fibrinogen levels: the Coronary Artery Risk Development in Young Adults (CARDIA) study.
Journal of thrombosis and haemostasis : JTH 2006;4(6):1279-87.
2006: Kelly A Volcik; Christie M Ballantyne; Josef Coresh; Aaron R Folsom; Kenneth K Wu; Eric Boerwinkle
P-selectin Thr715Pro polymorphism predicts P-selectin levels but not risk of incident coronary heart disease or ischemic stroke in a cohort of 14595 participants: the Atherosclerosis Risk in Communities Study.
Atherosclerosis 2006;186(1):74-9.
2006: Sharon L R Kardia; Lawrence F Bielak; Leslie A Lange; James M Cheverud; Eric Boerwinkle; Stephen T Turner; Patrick F Sheedy; Patricia A Peyser
Epistatic effects between two genes in the renin-angiotensin system and systolic blood pressure and coronary artery calcification.
Medical science monitor : international medical journal of experimental and clinical research 2006;12(4):CR150-8.
2006: Stephen T Turner; Patricia A Peyser; Sharon L R Kardia; Lawrence F Bielak; Patrick F Sheedy; Eric Boerwinkle; Mariza de Andrade
Genomic loci with pleiotropic effects on coronary artery calcification.
Atherosclerosis 2006;185(2):340-6.
2006: Jonathan C Cohen; Eric Boerwinkle; Thomas H Mosley; Helen H Hobbs
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.
The New England journal of medicine 2006;354(12):1264-72.
2006: Charles Chia-Chuen Hsu; Molly S Bray; WEN KAO; James S Pankow; Eric Boerwinkle; Josef Coresh
Genetic variation of the renin-angiotensin system and chronic kidney disease progression in black individuals in the atherosclerosis risk in communities study.
Journal of the American Society of Nephrology : JASN 2006;17(2):504-12.
2006: Jari H Stengård; Sharon L R Kardia; Sara C Hamon; Ruth Frikke-Schmidt; Anne Tybjaerg-Hansen; Veikko Salomaa; Eric Boerwinkle; Charles F Sing
Contribution of regulatory and structural variations in APOE to predicting dyslipidemia.
Journal of lipid research 2006;47(2):318-28.
2006: Sara C Hamon; Sharon L R Kardia; Eric Boerwinkle; Kiang Liu; Kathy Klos; andrew clark; Charles F Sing
Evidence for consistent intragenic and intergenic interactions between SNP effects in the APOA1/C3/A4/A5 gene cluster.
Human heredity 2006;61(2):87-96.
2006: Jason M Laramie; Jemma B Wilk; Steven C Hunt; R Curtis Ellison; Aravinda Chakravarti; Eric Boerwinkle; Richard H Myers
Evidence for a gene influencing heart rate on chromosome 5p13-14 in a meta-analysis of genome-wide scans from the NHLBI Family Blood Pressure Program.
BMC medical genetics 2006;7():17.
2006: Xiaodong Wu; Donghui Kan; Michael A Province; Thomas Quertermous; Dabeeru C Rao; Christy Chang; Thomas H Mosley; David Curb; Eric Boerwinkle; Richard S Cooper
An updated meta-analysis of genome scans for hypertension and blood pressure in the NHLBI Family Blood Pressure Program (FBPP).
American journal of hypertension 2006;19(1):122-7.
2005: Ron C Hoogeveen; Alanna Morrison; Eric Boerwinkle; J Shawn Miles; Charles E Rhodes; ALBERT SHARRETT; Christie M Ballantyne
Plasma MCP-1 level and risk for peripheral arterial disease and incident coronary heart disease: Atherosclerosis Risk in Communities study.
Atherosclerosis 2005;183(2):301-7.
2005: Christie M Ballantyne; Ron C Hoogeveen; Heejung Bang; Josef Coresh; Aaron R Folsom; Lloyd E Chambless; Merle Myerson; Kenneth K Wu; ALBERT SHARRETT; Eric Boerwinkle
Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident ischemic stroke in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study.
Archives of internal medicine 2005;165(21):2479-84.
2005: Dharmendrakumar A Patel; Shengxu Li; Wei Chen; Sathanur R Srinivasan; Eric Boerwinkle; Gerald S Berenson
G-6A polymorphism of the angiotensinogen gene and its association with left ventricular mass in asymptomatic young adults from a biethnic community: the Bogalusa Heart Study.
American journal of hypertension 2005;18(11):1437-41.
2005: andrew clark; Eric Boerwinkle; James E Hixson; Charles F Sing
Determinants of the success of whole-genome association testing.
Genome research 2005;15(11):1463-7.
2005: Jared D Sturgeon; Aaron R Folsom; Molly S Bray; Eric Boerwinkle; Christie M Ballantyne
Apolipoprotein E genotype and incident ischemic stroke: the Atherosclerosis Risk in Communities Study.
Stroke; a journal of cerebral circulation 2005;36(11):2484-6.
2005: Stephen T Turner; Gary L Schwartz; Arlene B Chapman; Eric Boerwinkle
WNK1 kinase polymorphism and blood pressure response to a thiazide diuretic.
Hypertension 2005;46(4):758-65.
2005: Myriam Fornage; Gerardo Heiss; Craig R Lee; Darryl C Zeldin; Molly S Bray; Peter A Doris; Eric Boerwinkle
The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke.
Human molecular genetics 2005;14(19):2829-37.
2005: Iftikhar J Kullo; Stephen T Turner; Eric Boerwinkle; Sharon L R Kardia; Mariza de Andrade
A novel quantitative trait locus on chromosome 1 with pleiotropic effects on HDL-cholesterol and LDL particle size in hypertensive sibships.
American journal of hypertension 2005;18(8):1084-90.
2005: Anke Hilse Maitland-van der Zee; Stephen T Turner; Gary L Schwartz; Arlene B Chapman; Olaf Klungel; Eric Boerwinkle
Demographic, environmental, and genetic predictors of metabolic side effects of hydrochlorothiazide treatment in hypertensive subjects.
American journal of hypertension 2005;18(8):1077-83.
2005: Andrei S Rodin; Eric Boerwinkle
Mining genetic epidemiology data with Bayesian networks I: Bayesian networks and example application (plasma apoE levels).
Bioinformatics (Oxford, England) 2005;21(15):3273-8.
2005: Jinying Zhao; Eric Boerwinkle; Momiao Xiong
An entropy-based statistic for genomewide association studies.
American journal of human genetics 2005;77(1):27-40.
2005: Christopher S Carlson; Shelley Force Aldred; Philip K Lee; Russell P Tracy; Stephen M Schwartz; Mark J Rieder; Kiang Liu; Dale O Williams; Carlos Iribarren; E Cora Lewis; Myriam Fornage; Eric Boerwinkle; Myron Gross; Cashell E Jaquish; Deborah A Nickerson; Richard Myers; David S Siscovick; Alexander P Reiner
Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels.
American journal of human genetics 2005;77(1):64-77.
2005: Donna K Arnett; Barry R Davis; Charles E Ford; Eric Boerwinkle; Catherine Leiendecker-Foster; Michael B Miller; Henry Black; John H Eckfeldt
Pharmacogenetic association of the angiotensin-converting enzyme insertion/deletion polymorphism on blood pressure and cardiovascular risk in relation to antihypertensive treatment: the Genetics of Hypertension-Associated Treatment (GenHAT) study.
Circulation 2005;111(25):3374-83.
2005: Charles C Hsu; WEN KAO; Josef Coresh; James S Pankow; Jane Marsh-Manzi; Eric Boerwinkle; Molly S Bray
Apolipoprotein E and progression of chronic kidney disease.
JAMA : the journal of the American Medical Association 2005;293(23):2892-9.
2005: Alanna C Morrison; Eric Boerwinkle; Stephen T Turner; Robert E Ferrell
Genome-wide linkage study of erythrocyte sodium-lithium countertransport.
American journal of hypertension 2005;18(5 Pt 1):653-6.
2005: Anke Hilse Maitland-van der Zee; Stephen T Turner; Gary L Schwartz; Arlene B Chapman; Olaf Klungel; Eric Boerwinkle
A multilocus approach to the antihypertensive pharmacogenetics of hydrochlorothiazide.
Pharmacogenetics and genomics 2005;15(5):287-93.
2005: Anke Hilse Maitland-van der Zee; Eric Boerwinkle
Pharmacogenetics of response to statins: where do we stand?
Current atherosclerosis reports 2005;7(3):204-8.
2005: Wei Chen; Shengxu Li; Sathanur R Srinivasan; Eric Boerwinkle; Gerald S Berenson
Autosomal genome scan for loci linked to blood pressure levels and trends since childhood: the Bogalusa Heart Study.
Hypertension 2005;45(5):954-9.
2005: Cruz A Hinojos; Eric Boerwinkle; Myriam Fornage; Peter A Doris
Combined genealogical, mapping, and expression approaches to identify spontaneously hypertensive rat hypertension candidate genes.
Hypertension 2005;45(4):698-704.
2005: Stephen T Turner; Myriam Fornage; Clifford R Jack; Thomas H Mosley; Sharon L R Kardia; Eric Boerwinkle; Mariza de Andrade
Genomic susceptibility loci for brain atrophy in hypertensive sibships from the GENOA study.
Hypertension 2005;45(4):793-8.
2005: Darrell L Ellsworth; Sean Coady; Wei Chen; Sathanur R Srinivasan; Eric Boerwinkle; Gerald S Berenson
Interactive effects between polymorphisms in the beta-adrenergic receptors and longitudinal changes in obesity.
Obesity research 2005;13(3):519-26.
2005: Javier D Finkielman; Gary L Schwartz; Arlene B Chapman; Eric Boerwinkle; Stephen T Turner
Lack of agreement between office and ambulatory blood pressure responses to hydrochlorothiazide.
American journal of hypertension 2005;18(3):398-402.
2005: Ping An; Barry I Freedman; Craig L Hanis; Yii-Der I Chen; Alan B Weder; Nicholas J Schork; Eric Boerwinkle; Michael A Province; Chao A Hsiung; Xiaodong Wu; Thomas Quertermous; Dabeeru C Rao
Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis.
Diabetes 2005;54(3):909-14.
2005: Kathy Klos; Sharon L R Kardia; James E Hixson; Stephen T Turner; Craig L Hanis; Eric Boerwinkle; Charles F Sing
Linkage analysis of plasma ApoE in three ethnic groups: multiple genes with context-dependent effects.
Annals of human genetics 2005;69(Pt 2):157-67.
2005: Kathy Klos; Sara C Hamon; andrew clark; Eric Boerwinkle; Kiang Liu; Charles F Sing
APOA5 polymorphisms influence plasma triglycerides in young, healthy African Americans and whites of the CARDIA Study.
Journal of lipid research 2005;46(3):564-71.
2005: Eric Jorgenson; Hua Tang; Maya Gadde; Michael A Province; Mark Leppert; Sharon L R Kardia; Nicholas J Schork; Richard Cooper; D C Rao; Eric Boerwinkle; Neil Risch
Ethnicity and human genetic linkage maps.
American journal of human genetics 2005;76(2):276-90.
2005: Hua Tang; Thomas Quertermous; Beatriz L Rodriguez; Sharon L R Kardia; Xiaofeng Zhu; Andrew Brown; James S Pankow; Michael A Province; Steven C Hunt; Eric Boerwinkle; Nicholas J Schork; Neil J Risch
Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies.
American journal of human genetics 2005;76(2):268-75.
2005: Andrei Rodin; Thomas H Mosley; andrew clark; Charles F Sing; Eric Boerwinkle
Mining genetic epidemiology data with Bayesian networks application to APOE gene variation and plasma lipid levels.
Journal of computational biology : a journal of computational molecular cell biology 2005;12(1):1-11.
2005: Iftikhar J Kullo; Mariza de Andrade; Eric Boerwinkle; Joseph P McConnell; Sharon L R Kardia; Stephen T Turner
Pleiotropic genetic effects contribute to the correlation between HDL cholesterol, triglycerides, and LDL particle size in hypertensive sibships.
American journal of hypertension 2005;18(1):99-103.
2005: Alan R Templeton; Taylor Maxwell; David Posada; Jari H Stengård; Eric Boerwinkle; Charles F Sing
Tree scanning: a method for using haplotype trees in phenotype/genotype association studies.
Genetics 2005;169(1):441-53.
2004: Sara C Hamon; J H Stengard; andrew clark; V Salomaa; Eric Boerwinkle; Charles F Sing
Evidence for non-additive influence of single nucleotide polymorphisms within the apolipoprotein E gene.
Annals of human genetics 2004;68(Pt 6):521-35.
2004: Sathanur R Srinivasan; Shengxu Li; Wei Chen; Rong Tang; M Gene Bond; Eric Boerwinkle; Gerald S Berenson
Q192R polymorphism of the paraoxanase 1 gene and its association with serum lipoprotein variables and carotid artery intima-media thickness in young adults from a biracial community. The Bogalusa Heart Study.
Atherosclerosis 2004;177(1):167-74.
2004: Wei Chen; Sathanur R Srinivasan; Shengxu Li; Eric Boerwinkle; Gerald S Berenson
Gender-specific influence of NO synthase gene on blood pressure since childhood: the Bogalusa Heart Study.
Hypertension 2004;44(5):668-73.
2004: Myriam Fornage; David S Lopez; Jeffrey M Roseman; David S Siscovick; Nathan D Wong; Eric Boerwinkle
Parental history of stroke and myocardial infarction predicts coronary artery calcification: The Coronary Artery Risk Development in Young Adults (CARDIA) study.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 2004;11(5):421-6.
2004: Iftikhar J Kullo; kent bailey; Lawrence F Bielak; Patrick F Sheedy; George G Klee; Sharon L R Kardia; Patricia A Peyser; Eric Boerwinkle; Stephen T Turner
Lack of association between lipoprotein(a) and coronary artery calcification in the Genetic Epidemiology Network of Arteriopathy (GENOA) study.
Mayo Clinic proceedings. Mayo Clinic 2004;79(10):1258-63.
2004: Iftikhar J Kullo; kent bailey; Joseph P McConnell; Patricia A Peyser; Lawrence F Bielak; Sharon L R Kardia; Patrick F Sheedy; Eric Boerwinkle; Stephen T Turner
Low-density lipoprotein particle size and coronary atherosclerosis in subjects belonging to hypertensive sibships.
American journal of hypertension 2004;17(9):845-51.
2004: Alanna C Morrison; Richard Cooper; Steven C Hunt; Cora E Lewis; Amy Luke; Thomas H Mosley; Eric Boerwinkle
Genome scan for hypertension in nonobese African Americans: the National Heart, Lung, and Blood Institute Family Blood Pressure Program.
American journal of hypertension 2004;17(9):834-8.
2004: D Michael Hallman; Sathanur R Srinivasan; Wei Chen; Eric Boerwinkle; Gerald S Berenson
The beta(2)-adrenergic receptor Arg16-gly polymorphism and interactions involving beta(2)- and beta(3)-adrenergic receptor polymorphisms are associated with variations in longitudinal serum lipid profiles: the Bogalusa Heart Study.
Metabolism: clinical and experimental 2004;53(9):1184-91.
2004: Teri A Manolio; Eric Boerwinkle; Christopher J O'Donnell; Alexander F Wilson
Genetics of ultrasonographic carotid atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(9):1567-77.
2004: Barry R Davis; Charles E Ford; Eric Boerwinkle; Donna K Arnett; John H Eckfeldt; Henry Black
Imputing gene-treatment interactions when the genotype distribution is unknown using case-only and putative placebo analyses--a new method for the Genetics of Hypertension Associated Treatment (GenHAT) study.
Statistics in medicine 2004;23(15):2413-27.
2004: Lorraine Frazier; Janet C Meininger; Dale Halsey Lea; Eric Boerwinkle
Genetic discoveries and nursing implications for complex disease prevention and management.
Journal of professional nursing : official journal of the American Association of Colleges of Nursing 2004;20(4):222-9.
2004: Wei Chen; Sathanur R Srinivasan; M Gene Bond; Rong Tang; Elaine M Urbina; Shengxu Li; Eric Boerwinkle; Gerald S Berenson
Nitric oxide synthase gene polymorphism (G894T) influences arterial stiffness in adults: The Bogalusa Heart Study.
American journal of hypertension 2004;17(7):553-9.
2004: Stephen T Turner; Sharon L R Kardia; Eric Boerwinkle; Mariza de Andrade
Multivariate linkage analysis of blood pressure and body mass index.
Genetic epidemiology 2004;27(1):64-73.
2004: John G O'Meara; Sharon L R Kardia; Jeffrey J Armon; C A Brown; Eric Boerwinkle; Stephen T Turner
Ethnic and sex differences in the prevalence, treatment, and control of dyslipidemia among hypertensive adults in the GENOA study.
Archives of internal medicine 2004;164(12):1313-8.
2004: Zhongming Zhao; Haipeng Li; Xiaozhuang Wu; Yixi Zhong; Keqin Zhang; Ya-Ping Zhang; Eric Boerwinkle; Yun-Xin Fu
Moderate mutation rate in the SARS coronavirus genome and its implications.
BMC evolutionary biology 2004;4():21.
2004: Stephanie M Fullerton; Anne V Buchanan; Vibhor Sonpar; Scott L Taylor; Joshua D Smith; Christopher S Carlson; Veikko Salomaa; Jari H Stengård; Eric Boerwinkle; andrew clark; Deborah A Nickerson; Kenneth M Weiss
The effects of scale: variation in the APOA1/C3/A4/A5 gene cluster.
Human genetics 2004;115(1):36-56.
2004: Paul R Daniels; Sharon L R Kardia; Craig L Hanis; C A Brown; Richard Hutchinson; Eric Boerwinkle; Stephen T Turner
Familial aggregation of hypertension treatment and control in the Genetic Epidemiology Network of Arteriopathy (GENOA) study.
The American journal of medicine 2004;116(10):676-81.
2004: Wei Chen; S Li; N R Cook; B A Rosner; Sathanur R Srinivasan; Eric Boerwinkle; Gerald S Berenson
An autosomal genome scan for loci influencing longitudinal burden of body mass index from childhood to young adulthood in white sibships: The Bogalusa Heart Study.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2004;28(4):462-9.
2004: D Michael Hallman; Spencer A Brown; Christie M Ballantyne; ALBERT SHARRETT; Eric Boerwinkle
Relationship between low-density lipoprotein subclasses and asymptomatic atherosclerosis in subjects from the Atherosclerosis Risk in Communities (ARIC) Study.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2004;9(2):190-202.
2004: Ruth Ann Barkley; Aravinda Chakravarti; Richard S Cooper; R Curtis Ellison; Steven C Hunt; Michael A Province; Stephen T Turner; Alan B Weder; Eric Boerwinkle
Positional identification of hypertension susceptibility genes on chromosome 2.
Hypertension 2004;43(2):477-82.
2004: Stephen T Turner; Clifford R Jack; Myriam Fornage; Thomas H Mosley; Eric Boerwinkle; Mariza de Andrade
Heritability of leukoaraiosis in hypertensive sibships.
Hypertension 2004;43(2):483-7.
2004: Vahid Afshar-Kharghan; Nena Matijevic-Aleksic; Chul Ahn; Eric Boerwinkle; Kenneth K Wu; José A López
The variable number of tandem repeat polymorphism of platelet glycoprotein Ibalpha and risk of coronary heart disease.
Blood 2004;103(3):963-5.
2004: Myriam Fornage; Eric Boerwinkle; Peter A Doris; David Jacobs; Kiang Liu; Nathan D Wong
Polymorphism of the soluble epoxide hydrolase is associated with coronary artery calcification in African-American subjects: The Coronary Artery Risk Development in Young Adults (CARDIA) study.
Circulation 2004;109(3):335-9.
2003: Iftikhar J Kullo; kent bailey; Sharon L R Kardia; Thomas H Mosley; Eric Boerwinkle; Stephen T Turner
Ethnic differences in peripheral arterial disease in the NHLBI Genetic Epidemiology Network of Arteriopathy (GENOA) study.
Vascular medicine (London, England) 2003;8(4):237-42.
2003: Xue Xin; Sathanur R Srinivasan; Wei Chen; Eric Boerwinkle; Gerald S Berenson
Interaction effect of Serine447Stop variant of the lipoprotein lipase gene and C-514T variant of the hepatic lipase gene on serum triglyceride levels in young adults: the Bogalusa Heart Study.
Metabolism: clinical and experimental 2003;52(10):1337-42.
2003: Stephen T Turner; Arlene B Chapman; Gary L Schwartz; Eric Boerwinkle
Effects of endothelial nitric oxide synthase, alpha-adducin, and other candidate gene polymorphisms on blood pressure response to hydrochlorothiazide.
American journal of hypertension 2003;16(10):834-9.
2003: Myriam Fornage; Michael W Swank; Eric Boerwinkle; Peter A Doris
Gene expression profiling and functional proteomic analysis reveal perturbed kinase-mediated signaling in genetic stroke susceptibility.
Physiological genomics 2003;15(1):75-83.
2003: Qiqing Huang; Yun-Xin Fu; Eric Boerwinkle
Comparison of strategies for selecting single nucleotide polymorphisms for case/control association studies.
Human genetics 2003;113(3):253-7.
2003: Zhongming Zhao; Yang-Xin Fu; David Hewett-Emmett; Eric Boerwinkle
Investigating single nucleotide polymorphism (SNP) density in the human genome and its implications for molecular evolution.
Gene 2003;312():207-13.
2003: Sathanur R Srinivasan; Shengxu Li; Wei Chen; Eric Boerwinkle; Gerald S Berenson
R219K polymorphism of the ABCA1 gene and its modulation of the variations in serum high-density lipoprotein cholesterol and triglycerides related to age and adiposity in white versus black young adults. The Bogalusa heart study.
Metabolism: clinical and experimental 2003;52(7):930-4.
2003: Wei Chen; Sathanur R Srinivasan; Eric Boerwinkle; Gerald S Berenson
Hepatic lipase promoter C-514T polymorphism influences serial changes in HDL cholesterol levels since childhood: the Bogalusa Heart Study.
Atherosclerosis 2003;169(1):175-82.
2003: Iftikhar J Kullo; Joseph P McConnell; kent bailey; Sharon L R Kardia; Lawrence F Bielak; Patricia A Peyser; Patrick F Sheedy; Eric Boerwinkle; Stephen T Turner
Relation of C-reactive protein and fibrinogen to coronary artery calcium in subjects with systemic hypertension.
The American journal of cardiology 2003;92(1):56-8.
2003: Ruth Ann Barkley; Andrew C Brown; Craig L Hanis; Sharon L R Kardia; Stephen T Turner; Eric Boerwinkle
Lack of genetic linkage evidence for a trans-acting factor having a large effect on plasma lipoprotein[a] levels in African Americans.
Journal of lipid research 2003;44(7):1301-5.
2003: Olga Y Gorlova; Christopher I Amos; Nancy W Wang; Sanjay Shete; Stephen T Turner; Eric Boerwinkle
Genetic linkage and imprinting effects on body mass index in children and young adults.
European journal of human genetics : EJHG 2003;11(6):425-32.
2003: WEN KAO; Josef Coresh; Alan R Shuldiner; Eric Boerwinkle; Molly S Bray; frederick brancati
Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study.
Diabetes 2003;52(6):1568-72.
2003: Andrew F Olshan; Rongling Li; James S Pankow; Molly S Bray; Herman A Tyroler; Lloyd E Chambless; Eric Boerwinkle; Gary S Pittman; Douglas A Bell
Risk of atherosclerosis: interaction of smoking and glutathione S-transferase genes.
Epidemiology (Cambridge, Mass.) 2003;14(3):321-7.
2003: Shengxu Li; Wei Chen; Sathanur R Srinivasan; Eric Boerwinkle; Gerald S Berenson
The peroxisome proliferator-activated receptor-gamma2 gene polymorphism (Pro12Ala) beneficially influences insulin resistance and its tracking from childhood to adulthood: the Bogalusa Heart Study.
Diabetes 2003;52(5):1265-9.
2003: Alanna C Morrison; Andrew Brown; Sharon L R Kardia; Stephen T Turner; Eric Boerwinkle
Evaluating the context-dependent effect of family history of stroke in a genome scan for hypertension.
Stroke; a journal of cerebral circulation 2003;34(5):1170-5.
2003: Momiao Xiong; Jinying Zhao; Eric Boerwinkle
Haplotype block linkage disequilibrium mapping.
Frontiers in bioscience : a journal and virtual library 2003;8():a85-93.
2003: Mariza de Andrade; Brooke L Fridley; Eric Boerwinkle; Stephen Turner
Diagnostic tools in linkage analysis for quantitative traits.
Genetic epidemiology 2003;24(4):302-8.
2003: Kenneth K Wu; Nena Aleksic; Christie M Ballantyne; Chul Ahn; Harinder Juneja; Eric Boerwinkle
Interaction between soluble thrombomodulin and intercellular adhesion molecule-1 in predicting risk of coronary heart disease.
Circulation 2003;107(13):1729-32.
2003: Xiaodong Wu; Richard S Cooper; Eric Boerwinkle; Stephen T Turner; Steven C Hunt; Richard H Myers; Richard A Olshen; David Curb; Xiaofeng Zhu; Donghui Kan; Amy Luke
Combined analysis of genomewide scans for adult height: results from the NHLBI Family Blood Pressure Program.
European journal of human genetics : EJHG 2003;11(3):271-4.
2003: Sharon L R Kardia; Laura S Rozek; Julia Krushkal; Robert E Ferrell; Stephen T Turner; Richard Hutchinson; Andrew Brown; Charles F Sing; Eric Boerwinkle
Genome-wide linkage analyses for hypertension genes in two ethnically and geographically diverse populations.
American journal of hypertension 2003;16(2):154-7.
2003: Michael A Province; Sharon L R Kardia; Koustubh Ranade; Dabeeru C Rao; Bonnie A Thiel; Richard S Cooper; Neil Risch; Stephen T Turner; David R Cox; Steven C Hunt; Alan B Weder; Eric Boerwinkle
A meta-analysis of genome-wide linkage scans for hypertension: the National Heart, Lung and Blood Institute Family Blood Pressure Program.
American journal of hypertension 2003;16(2):144-7.
2003: Vesna D Garovic; Michael J Joyner; Niki M Dietz; Eric Boerwinkle; Stephen T Turner
Beta(2)-adrenergic receptor polymorphism and nitric oxide-dependent forearm blood flow responses to isoproterenol in humans.
The Journal of physiology 2003;546(Pt 2):583-9.
2003: Stephen T Turner; Eric Boerwinkle
Genetics of blood pressure, hypertensive complications, and antihypertensive drug responses.
Pharmacogenomics 2003;4(1):53-65.
2002: Lama S Jamjoum; Lawrence F Bielak; Stephen T Turner; Patrick F Sheedy II; Eric Boerwinkle; Trivellore E Raghunathan; Patricia A Peyser
Relationship of blood pressure measures with coronary artery calcification.
Medical science monitor : international medical journal of experimental and clinical research 2002;8(12):CR775-81.
2002: Sharon E Johnatty; Maha Abdellatif; Lawrence Shimmin; Richard B Clark; Eric Boerwinkle
Beta 2 adrenergic receptor 5' haplotypes influence promoter activity.
British journal of pharmacology 2002;137(8):1213-6.
2002: Olga Y Gorlova; Christopher I Amos; D K Zhu; W Wang; S Turner; Eric Boerwinkle
Power of a simplified multivariate test for genetic linkage.
Annals of human genetics 2002;66(Pt 5-6):407-17.
2002: Javier D Finkielman; Gary L Schwartz; Arlene B Chapman; Eric Boerwinkle; Stephen T Turner
Reproducibility of blood pressure response to hydrochlorothiazide.
Journal of clinical hypertension (Greenwich, Conn.) 2002;4(6):408-12.
2002: Zhongming Zhao; Eric Boerwinkle
Neighboring-nucleotide effects on single nucleotide polymorphisms: a study of 2.6 million polymorphisms across the human genome.
Genome research 2002;12(11):1679-86.
2002: Gary L Schwartz; Arlene B Chapman; Eric Boerwinkle; Robert M Kisabeth; Stephen T Turner
Screening for primary aldosteronism: implications of an increased plasma aldosterone/renin ratio.
Clinical chemistry 2002;48(11):1919-23.
2002: Gary L Schwartz; Stephen T Turner; Arlene B Chapman; Eric Boerwinkle
Interacting effects of gender and genotype on blood pressure response to hydrochlorothiazide.
Kidney international 2002;62(5):1718-23.
2002: Myriam Fornage; Cruz A Hinojos; Barbara W Nurowska; Eric Boerwinkle; Bruce D Hammock; Christophe H P Morisseau; Peter A Doris
Polymorphism in soluble epoxide hydrolase and blood pressure in spontaneously hypertensive rats.
Hypertension 2002;40(4):485-90.
2002: Jari H Stengård; andrew clark; Kenneth M Weiss; Sharon L R Kardia; Deborah A Nickerson; Veikko Salomaa; Christian Ehnholm; Eric Boerwinkle; Charles F Sing
Contributions of 18 additional DNA sequence variations in the gene encoding apolipoprotein E to explaining variation in quantitative measures of lipid metabolism.
American journal of human genetics 2002;71(3):501-17.
2002: A J Marian; Eric Boerwinkle
"Into thin air" and the genetics of complex traits.
Circulation 2002;106(7):768-9.
2002: Patricia A Peyser; Lawrence F Bielak; Julia S Chu; Stephen T Turner; Darrell L Ellsworth; Eric Boerwinkle; Patrick F Sheedy
Heritability of coronary artery calcium quantity measured by electron beam computed tomography in asymptomatic adults.
Circulation 2002;106(3):304-8.
2002: Stephanie M Fullerton; andrew clark; Kenneth M Weiss; Scott L Taylor; Jari H Stengård; Veikko Salomaa; Eric Boerwinkle; Deborah A Nickerson
Sequence polymorphism at the human apolipoprotein AII gene ( APOA2): unexpected deficit of variation in an African-American sample.
Human genetics 2002;111(1):75-87.
2002: Darrell L Ellsworth; Sean Coady; Wei Chen; Sathanur R Srinivasan; Abdalla Elkasabany; Jeanette Gustat; Eric Boerwinkle; Gerald S Berenson
Influence of the beta2-adrenergic receptor Arg16Gly polymorphism on longitudinal changes in obesity from childhood through young adulthood in a biracial cohort: the Bogalusa Heart Study.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2002;26(7):928-37.
2002: Alanna C Morrison; Molly S Bray; Aaron R Folsom; Eric Boerwinkle
ADD1 460W allele associated with cardiovascular disease in hypertensive individuals.
Hypertension 2002;39(6):1053-7.
2002: Momiao Xiong; Jinying Zhao; Eric Boerwinkle
Generalized T2 test for genome association studies.
American journal of human genetics 2002;70(5):1257-68.
2002: Alanna C Morrison; Christie M Ballantyne; Molly S Bray; Lloyd E Chambless; ALBERT SHARRETT; Eric Boerwinkle
LPL polymorphism predicts stroke risk in men.
Genetic epidemiology 2002;22(3):233-42.
2002: Leslie A Lange; Ethan M Lange; Lawrence F Bielak; Carl D Langefeld; Sharon L R Kardia; Patrick Royston; Stephen T Turner; Patrick F Sheedy; Eric Boerwinkle; Patricia A Peyser
Autosomal genome-wide scan for coronary artery calcification loci in sibships at high risk for hypertension.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(3):418-23.
2002: Arlene B Chapman; Gary L Schwartz; Eric Boerwinkle; Stephen T Turner
Predictors of antihypertensive response to a standard dose of hydrochlorothiazide for essential hypertension.
Kidney international 2002;61(3):1047-55.
2002: Nena Aleksic; Chul Ahn; Yao-Wei Wang; Harinder Juneja; Aaron R Folsom; Eric Boerwinkle; Kenneth K Wu
Factor XIIIA Val34Leu polymorphism does not predict risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) Study.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(2):348-52.
2002: Donna K Arnett; Eric Boerwinkle; Barry R Davis; John H Eckfeldt; Charles E Ford; Henry Black
Pharmacogenetic approaches to hypertension therapy: design and rationale for the Genetics of Hypertension Associated Treatment (GenHAT) study.
The pharmacogenomics journal 2002;2(5):309-17.
2002: Michael J Garant; WEN KAO; frederick brancati; Josef Coresh; Tejal M Rami; Craig L Hanis; Eric Boerwinkle; Alan R Shuldiner
SNP43 of CAPN10 and the risk of type 2 Diabetes in African-Americans: the Atherosclerosis Risk in Communities Study.
Diabetes 2002;51(1):231-7.
2001: Wei Chen; Sathanur R Srinivasan; Abdalla Elkasabany; Darrell L Ellsworth; Eric Boerwinkle; Gerald S Berenson
Influence of lipoprotein lipase serine 447 stop polymorphism on tracking of triglycerides and HDL cholesterol from childhood to adulthood and familial risk of coronary artery disease: the Bogalusa heart study.
Atherosclerosis 2001;159(2):367-73.
2001: Wei Chen; Sathanur R Srinivasan; Abdalla Elkasabany; Darrell L Ellsworth; Eric Boerwinkle; Gerald S Berenson
Combined effects of endothelial nitric oxide synthase gene polymorphism (G894T) and insulin resistance status on blood pressure and familial risk of hypertension in young adults: the Bogalusa Heart Study.
American journal of hypertension 2001;14(10):1046-52.
2001: Stephen T Turner; Gary L Schwartz; Arlene B Chapman; Eric Boerwinkle
Use of gene markers to guide antihypertensive therapy.
Current hypertension reports 2001;3(5):410-5.
2001: D M Hallman; S R Srinivasan; A Elkasabany; Eric Boerwinkle; G S Berenson
The Ser(447)-Stop polymorphism of lipoprotein lipase is associated with variation in longitudinal serum high-density lipoprotein-cholesterol profiles: the Bogalusa Heart Study.
Metabolism: clinical and experimental 2001;50(8):894-904.
2001: Darrell L Ellsworth; Lawrence F Bielak; S T Turner; P F Sheedy; Eric Boerwinkle; Patricia A Peyser
Gender- and age-dependent relationships between the E-selectin S128R polymorphism and coronary artery calcification.
Journal of molecular medicine (Berlin, Germany) 2001;79(7):390-8.
2001: Kathy Klos; Sharon L R Kardia; RE Ferrell; Stephen T Turner; Eric Boerwinkle; Charles F Sing
Genome-wide linkage analysis reveals evidence of multiple regions that influence variation in plasma lipid and apolipoprotein levels associated with risk of coronary heart disease.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(6):971-8.
2001: Dongchuan Guo; Sumera N Hasham; S Q Kuang; Carl J Vaughan; Eric Boerwinkle; Hongjiang Chen; Dianne Abuelo; Harry C Dietz; Craig T Basson; Sanjay Shete; Dianna M Milewicz
Familial thoracic aortic aneurysms and dissections: genetic heterogeneity with a major locus mapping to 5q13-14.
Circulation 2001;103(20):2461-8.
2001: Alanna C Morrison; P A Doris; Aaron R Folsom; F J Nieto; Eric Boerwinkle
G-protein beta3 subunit and alpha-adducin polymorphisms and risk of subclinical and clinical stroke.
Stroke; a journal of cerebral circulation 2001;32(4):822-9.
2001: Kenneth K Wu; Nena Aleksic; Chul Ahn; Eric Boerwinkle; Aaron R Folsom; Harinder Juneja
Thrombomodulin Ala455Val polymorphism and risk of coronary heart disease.
Circulation 2001;103(10):1386-9.
2001: Stephen T Turner; Gary L Schwartz; Arlene B Chapman; Eric Boerwinkle
C825T polymorphism of the G protein beta(3)-subunit and antihypertensive response to a thiazide diuretic.
Hypertension 2001;37(2 Pt 2):739-43.
2001: ALBERT SHARRETT; Gerardo Heiss; Lloyd E Chambless; Eric Boerwinkle; Sean Coady; Aaron R Folsom; W Patsch
Metabolic and lifestyle determinants of postprandial lipemia differ from those of fasting triglycerides: The Atherosclerosis Risk In Communities (ARIC) study.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(2):275-81.
2001: Q Huang; Alanna C Morrison; Eric Boerwinkle
Linkage disequilibrium structure and its impact on the localization of a candidate functional mutation.
Genetic epidemiology 2001;21 Suppl 1():S620-5.
2001: Stephen T Turner; Gary L Schwartz; Arlene B Chapman; W D Hall; Eric Boerwinkle
Antihypertensive pharmacogenetics: getting the right drug into the right patient.
Journal of hypertension 2001;19(1):1-11.
2001: Carrie L Pfaff; Esteban J Parra; Carolina Bonilla; Kevin Hiester; Paul M McKeigue; M I Kamboh; R G Hutchinson; R E Ferrell; Eric Boerwinkle; Mark D Shriver
Population structure in admixed populations: effect of admixture dynamics on the pattern of linkage disequilibrium.
American journal of human genetics 2001;68(1):198-207.
2000: Stephen T Turner; Eric Boerwinkle
Genetics of hypertension, target-organ complications, and response to therapy.
Circulation 2000;102(20 Suppl 4):IV40-5.
2000: Alan R Templeton; Kenneth M Weiss; D A Nickerson; Eric Boerwinkle; Charles F Sing
Cladistic structure within the human Lipoprotein lipase gene and its implications for phenotypic association studies.
Genetics 2000;156(3):1259-75.
2000: Nena Aleksic; Harinder Juneja; Aaron R Folsom; Chul Ahn; Eric Boerwinkle; Lloyd E Chambless; Kenneth K Wu
Platelet Pl(A2) allele and incidence of coronary heart disease: results from the Atherosclerosis Risk In Communities (ARIC) Study.
Circulation 2000;102(16):1901-5.
2000: Deborah A Nickerson; Scott L Taylor; Stephanie M Fullerton; Kenneth M Weiss; andrew clark; Jari H Stengård; Veikko Salomaa; Eric Boerwinkle; Charles F Sing
Sequence diversity and large-scale typing of SNPs in the human apolipoprotein E gene.
Genome research 2000;10(10):1532-45.
2000: Stephanie M Fullerton; andrew clark; Kenneth M Weiss; Deborah A Nickerson; Scott L Taylor; J H Stengârd; Veikko Salomaa; E Vartiainen; M Perola; Eric Boerwinkle; Charles F Sing
Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism.
American journal of human genetics 2000;67(4):881-900.
2000: A C Morrison; M Fornage; D Liao; Eric Boerwinkle
Parental history of stroke predicts subclinical but not clinical stroke: the Atherosclerosis Risk in Communities Study.
Stroke; a journal of cerebral circulation 2000;31(9):2098-102.
2000: Michael A Province; Eric Boerwinkle; Aravinda Chakravarti; R Cooper; M Fornage; M Leppert; Neil Risch; Koustubh Ranade
Lack of association of the angiotensinogen-6 polymorphism with blood pressure levels in the comprehensive NHLBI Family Blood Pressure Program. National Heart, Lung and Blood Institute.
Journal of hypertension 2000;18(7):867-76.
2000: Molly S Bray; Julia Krushkal; L Li; R Ferrell; Sharon L R Kardia; Charles F Sing; Stephen T Turner; Eric Boerwinkle
Positional genomic analysis identifies the beta(2)-adrenergic receptor gene as a susceptibility locus for human hypertension.
Circulation 2000;101(25):2877-82.
2000: Molly S Bray; L Li; S T Turner; S L Kardia; Eric Boerwinkle
Association and linkage analysis of the alpha-adducin gene and blood pressure.
American journal of hypertension 2000;13(6 Pt 1):699-703.
2000: N Larson; R Hutchinson; Eric Boerwinkle
Lack of association of 3 functional gene variants with hypertension in African Americans.
Hypertension 2000;35(6):1297-300.
2000: Molly S Bray; Eric Boerwinkle; C L Hanis
Sequence variation within the neuropeptide Y gene and obesity in Mexican Americans.
Obesity research 2000;8(3):219-26.
2000: Rongling Li; Eric Boerwinkle; Andrew F Olshan; Lloyd E Chambless; James S Pankow; Herman A Tyroler; Molly S Bray; Gary S Pittman; Douglas A Bell; Gerardo Heiss
Glutathione S-transferase genotype as a susceptibility factor in smoking-related coronary heart disease.
Atherosclerosis 2000;149(2):451-62.
2000: Molly S Bray; Eric Boerwinkle
The role of beta(2)-adrenergic receptor variation in human hypertension.
Current hypertension reports 2000;2(1):39-43.
2000: Alan R Templeton; andrew clark; Kenneth M Weiss; D A Nickerson; Eric Boerwinkle; Charles F Sing
Recombinational and mutational hotspots within the human lipoprotein lipase gene.
American journal of human genetics 2000;66(1):69-83.
1999: D M Hallman; B E Groenemeijer; J W Jukema; Eric Boerwinkle; J J Kastelein
Analysis of lipoprotein lipase haplotypes reveals associations not apparent from analysis of the constituent loci.
Annals of human genetics 1999;63(Pt 6):499-510.
1999: A C Morrison; frederick brancati; A R Folsom; Louis C Smith; Eric Boerwinkle
Beta3-adrenergic receptor Trp64Arg polymorphism does not predict incident CHD or carotid intima-media thickness in a community-based sample of whites: the ARIC study. Atherosclerosis Risk in Communities.
Human genetics 1999;105(4):314-9.
1999: Stephen T Turner; Eric Boerwinkle; Charles F Sing
Context-dependent associations of the ACE I/D polymorphism with blood pressure.
Hypertension 1999;34(4 Pt 2):773-8.
1999: Hsien-Hsien Lei; Josef Coresh; Alan R Shuldiner; Eric Boerwinkle; frederick brancati
Variants of the insulin receptor substrate-1 and fatty acid binding protein 2 genes and the risk of type 2 diabetes, obesity, and hyperinsulinemia in African-Americans: the Atherosclerosis Risk in Communities Study.
Diabetes 1999;48(9):1868-72.
1999: Julia Krushkal; R Ferrell; Stephen Mockrin; Stephen T Turner; Charles F Sing; Eric Boerwinkle
Genome-wide linkage analyses of systolic blood pressure using highly discordant siblings.
Circulation 1999;99(11):1407-10.
1999: Molly S Bray; Eric Boerwinkle; C L Hanis
Linkage analysis of candidate obesity genes among the Mexican-American population of Starr County, Texas.
Genetic epidemiology 1999;16(4):397-411.
1998: M M Xiong; Julia Krushkal; Eric Boerwinkle
TDT statistics for mapping quantitative trait loci.
Annals of human genetics 1998;62(Pt 5):431-52.
1998: Julia Krushkal; M Xiong; R Ferrell; Charles F Sing; Stephen T Turner; Eric Boerwinkle
Linkage and association of adrenergic and dopamine receptor genes in the distal portion of the long arm of chromosome 5 with systolic blood pressure variation.
Human molecular genetics 1998;7(9):1379-83.
1998: andrew clark; Kenneth M Weiss; Deborah A Nickerson; Scott L Taylor; Anne V Buchanan; Jari H Stengård; Veikko Salomaa; E Vartiainen; M Perola; Eric Boerwinkle; Charles F Sing
Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase.
American journal of human genetics 1998;63(2):595-612.
1998: Deborah A Nickerson; Scott L Taylor; Kenneth M Weiss; andrew clark; R G Hutchinson; Jari H Stengård; Veikko Salomaa; E Vartiainen; Eric Boerwinkle; Charles F Sing
DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene.
Nature genetics 1998;19(3):233-40.
1998: GP Page; Christopher I Amos; Eric Boerwinkle
The quantitative LOD score: test statistic and sample size for exclusion and linkage of quantitative traits in human sibships.
American journal of human genetics 1998;62(4):962-8.
1997: S J Hwang; Christie M Ballantyne; ALBERT SHARRETT; Louis C Smith; C E Davis; A M Gotto; Eric Boerwinkle
Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: the Atherosclerosis Risk In Communities (ARIC) study.
Circulation 1997;96(12):4219-25.
1997: D Michael Hallman; D L Ellsworth; Eric Boerwinkle
Molecular and genetic approaches to the study of cardiovascular disease.
Journal of cardiovascular risk 1997;4(5-6):325-31.
1997: Christopher I Amos; J Krushkal; TJ Thiel; A Young; D K Zhu; Eric Boerwinkle; Mariza de Andrade
Comparison of model-free linkage mapping strategies for the study of a complex trait.
Genetic epidemiology 1997;14(6):743-8.
1997: D L Ellsworth; D Michael Hallman; Eric Boerwinkle
Impact of the Human Genome Project on epidemiologic research.
Epidemiologic reviews 1997;19(1):3-13.
1996: Molly S Bray; Eric Boerwinkle; Craig L Hanis
OB gene not linked to human obesity in Mexican American affected sib pairs from Starr County, Texas.
Human genetics 1996;98(5):590-5.
1996: L Chen; W Patsch; Eric Boerwinkle
HindIII DNA polymorphism in the lipoprotein lipase gene and plasma lipid phenotypes and carotid artery atherosclerosis.
Human genetics 1996;98(5):551-6.
1996: A P Surguchov; GP Page; Louis C Smith; Wolfgang Patsch; Eric Boerwinkle
Polymorphic markers in apolipoprotein C-III gene flanking regions and hypertriglyceridemia.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(8):941-7.
1996: Craig L Hanis; Eric Boerwinkle; R Chakraborty; D L Ellsworth; Patrick Concannon; B Stirling; V A Morrison; B Wapelhorst; Richard S Spielman; K J Gogolin-Ewens; J M Shepard; S R Williams; N Risch; D Hinds; Naoko Iwasaki; Makiko Ogata; Y Omori; C Petzold; H Rietzch; H E Schröder; J Schulze; Nancy J Cox; Stephan Menzel; V V Boriraj; X Chen; L R Lim; TH Lindner; L E Mereu; Y Q Wang; Kun-san Xiang; K Yamagata; Y Yang; Graeme I Bell
A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2.
Nature genetics 1996;13(2):161-6.
1996: Christopher I Amos; D K Zhu; Eric Boerwinkle
Assessing genetic linkage and association with robust components of variance approaches.
Annals of human genetics 1996;60(Pt 2):143-60.
1996: Eric Boerwinkle; D L Ellsworth; D M Hallman; A Biddinger
Genetic analysis of atherosclerosis: a research paradigm for the common chronic diseases.
Human molecular genetics 1996;5 Spec No():1405-10.
1995: Myriam Fornage; S T Turner; Charles F Sing; Eric Boerwinkle
Variation at the M235T locus of the angiotensinogen gene and essential hypertension: a population-based case-control study from Rochester, Minnesota.
Human genetics 1995;96(3):295-300.
1995: A P Surguchov; Eric Boerwinkle; ALBERT SHARRETT; Wolfgang Patsch
Effect of apolipoprotein E polymorphism on fasting retinyl palmitate level.
Biochemical and molecular medicine 1995;55(2):156-7.
1995: Mariza de Andrade; I Thandi; S Brown; A Gotto; W Patsch; Eric Boerwinkle
Relationship of the apolipoprotein E polymorphism with carotid artery atherosclerosis.
American journal of human genetics 1995;56(6):1379-90.
1995: D L Ellsworth; M D Shriver; Eric Boerwinkle
Nucleotide sequence analysis of the apolipoprotein B 3' VNTR.
Human molecular genetics 1995;4(5):937-44.
1995: Vincent Mooser; F P Mancini; S Bopp; A Pethö-Schramm; Rudy Guerra; Eric Boerwinkle; H J Müller; Helen H Hobbs
Sequence polymorphisms in the apo(a) gene associated with specific levels of Lp(a) in plasma.
Human molecular genetics 1995;4(2):173-81.
1995: M H Carrejo; ALBERT SHARRETT; W Patsch; Eric Boerwinkle
No association of apolipoprotein A-IV codon 347 and 360 variation with atherosclerosis and lipid transport in a sample of mixed hyperlipidemics.
Genetic epidemiology 1995;12(4):371-80.
1994: Allan Gaw; Eric Boerwinkle; Jonathan C Cohen; Helen H Hobbs
Comparative analysis of the apo(a) gene, apo(a) glycoprotein, and plasma concentrations of Lp(a) in three ethnic groups. Evidence for no common "null" allele at the apo(a) locus.
The Journal of clinical investigation 1994;93(6):2526-34.
1994: Wolfgang Patsch; ALBERT SHARRETT; I Y Chen; Y C Lin-Lee; S A Brown; Antonio M Gotto; Eric Boerwinkle
Associations of allelic differences at the A-I/C-III/A-IV gene cluster with carotid artery intima-media thickness and plasma lipid transport in hypercholesterolemic-hypertriglyceridemic humans.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(6):874-83.
1994: Eric Boerwinkle; S Brown; ALBERT SHARRETT; Gerardo Heiss; W Patsch
Apolipoprotein E polymorphism influences postprandial retinyl palmitate but not triglyceride concentrations.
American journal of human genetics 1994;54(2):341-60.
1994: D M Hallman; Sophie Visvikis; Josiane Steinmetz; Eric Boerwinkle
The effect of variation in the apolipoprotein B gene on plasmid lipid and apolipoprotein B levels. I. A likelihood-based approach to cladistic analysis.
Annals of human genetics 1994;58(Pt 1):35-64.
1993: S A Brown; Joel D Morrisett; Eric Boerwinkle; R Hutchinson; Wolfgang Patsch
The relation of lipoprotein[a] concentrations and apolipoprotein[a] phenotypes with asymptomatic atherosclerosis in subjects of the Atherosclerosis Risk in Communities (ARIC) Study.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(11):1558-66.
1993: David J Moliterno; Richard A Lange; Robert S Meidell; J E Willard; C C Leffert; Robert D Gerard; Eric Boerwinkle; Helen H Hobbs; L David Hillis
Relation of plasma lipoprotein(a) to infarct artery patency in survivors of myocardial infarction.
Circulation 1993;88(3):935-40.
1993: M D Shriver; L Jin; R Chakraborty; Eric Boerwinkle
VNTR allele frequency distributions under the stepwise mutation model: a computer simulation approach.
Genetics 1993;134(3):983-93.
1992: M D Shriver; G Siest; Eric Boerwinkle
Length and sequence variation in the apolipoprotein B intron 20 Alu repeat.
Genomics 1992;14(2):449-54.
1992: C Sandholzer; N Saha; J D Kark; A Rees; W Jaross; Hans Dieplinger; Friedrich Hoppichler; Eric Boerwinkle; Gerd Utermann
Apo(a) isoforms predict risk for coronary heart disease. A study in six populations.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1992;12(10):1214-26.
1992: Eric Boerwinkle; C C Leffert; J Lin; Carolin Lackner; G Chiesa; Helen H Hobbs
Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations.
The Journal of clinical investigation 1992;90(1):52-60.
1992: C Sandholzer; Eric Boerwinkle; N Saha; M C Tong; Gerd Utermann
Apolipoprotein(a) phenotypes, Lp(a) concentration and plasma lipid levels in relation to coronary heart disease in a Chinese population: evidence for the role of the apo(a) gene in coronary heart disease.
The Journal of clinical investigation 1992;89(3):1040-6.
1992: Myriam Fornage; L Chan; G Siest; Eric Boerwinkle
Allele frequency distribution of the (TG)n(AG)m microsatellite in the apolipoprotein C-II gene.
Genomics 1992;12(1):63-8.
1991: Eric Boerwinkle; S A Brown; K Rohrbach; A M Gotto; W Patsch
Role of apolipoprotein E and B gene variation in determining response of lipid, lipoprotein, and apolipoprotein levels to increased dietary cholesterol.
American journal of human genetics 1991;49(6):1145-54.
1991: Eric Boerwinkle; S H Chen; S Visvikis; Craig L Hanis; G Siest; L Chan
Signal peptide-length variation in human apolipoprotein B gene. Molecular characteristics and association with plasma glucose levels.
Diabetes 1991;40(11):1539-44.
1991: D M Hallman; Eric Boerwinkle; N Saha; C Sandholzer; H J Menzel; A Csázár; Gerd Utermann
The apolipoprotein E polymorphism: a comparison of allele frequencies and effects in nine populations.
American journal of human genetics 1991;49(2):338-49.
1991: Carolin Lackner; Eric Boerwinkle; C C Leffert; T Rahmig; Helen H Hobbs
Molecular basis of apolipoprotein (a) isoform size heterogeneity as revealed by pulsed-field gel electrophoresis.
The Journal of clinical investigation 1991;87(6):2153-61.
1991: C Sandholzer; D M Hallman; N Saha; G Sigurdsson; Carolin Lackner; Albert Császár; Eric Boerwinkle; Gerd Utermann
Effects of the apolipoprotein(a) size polymorphism on the lipoprotein(a) concentration in 7 ethnic groups.
Human genetics 1991;86(6):607-14.
1991: M D Shriver; Eric Boerwinkle; D Hewett-Emmett; Craig L Hanis
Frequency and effects of apolipoprotein E polymorphism in Mexican-American NIDDM subjects.
Diabetes 1991;40(3):334-7.
1991: R Chakraborty; Myriam Fornage; R Gueguen; Eric Boerwinkle
Population genetics of hypervariable loci: analysis of PCR based VNTR polymorphism within a population.
EXS 1991;58():127-43.
1990: Eric Boerwinkle; Craig L Hanis; L Chan
A unique length polymorphism in the signal peptide region of the apolipoprotein B gene in Mexican-Americans.
Nucleic acids research 1990;18(23):7193.
1990: Eric Boerwinkle; Sophie Visvikis; L Chan
Two polymorphisms for amino acid substitutions in the APOA4 gene.
Nucleic acids research 1990;18(16):4966.
1990: Mary Seed; Friedrich Hoppichler; David A Reaveley; S McCarthy; G R Thompson; Eric Boerwinkle; Gerd Utermann
Relation of serum lipoprotein(a) concentration and apolipoprotein(a) phenotype to coronary heart disease in patients with familial hypercholesterolemia.
The New England journal of medicine 1990;322(21):1494-9.
1990: H J Menzel; G Sigurdsson; Eric Boerwinkle; S Schrangl-Will; Hans Dieplinger; Gerd Utermann
Frequency and effect of human apolipoprotein A-IV polymorphism on lipid and lipoprotein levels in an Icelandic population.
Human genetics 1990;84(4):344-6.
1990: S A Brown; Eric Boerwinkle; F K Kashanian; N Swanson; Wolfgang Patsch
Variation in concentration of lipids, lipoprotein lipids, and apolipoproteins A-I and B in plasma from healthy women.
Clinical chemistry 1990;36(2):207-10.
1989: Gerd Utermann; Friedrich Hoppichler; Hans Dieplinger; Mary Seed; G Thompson; Eric Boerwinkle
Defects in the low density lipoprotein receptor gene affect lipoprotein (a) levels: multiplicative interaction of two gene loci associated with premature atherosclerosis.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(11):4171-4.
1989: Eric Boerwinkle; L Chan
A three codon insertion/deletion polymorphism in the signal peptide region of the human apolipoprotein B (APOB) gene directly typed by the polymerase chain reaction.
Nucleic acids research 1989;17(10):4003.
1989: Eric Boerwinkle; H J Menzel; Hans Georg Kraft; Gerd Utermann
Genetics of the quantitative Lp(a) lipoprotein trait. III. Contribution of Lp(a) glycoprotein phenotypes to normal lipid variation.
Human genetics 1989;82(1):73-8.
1989: Eric Boerwinkle; W J Xiong; E Fourest; L Chan
Rapid typing of tandemly repeated hypervariable loci by the polymerase chain reaction: application to the apolipoprotein B 3' hypervariable region.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(1):212-6.
1988: H J Menzel; Eric Boerwinkle; S Schrangl-Will; Gerd Utermann
Human apolipoprotein A-IV polymorphism: frequency and effect on lipid and lipoprotein levels.
Human genetics 1988;79(4):368-72.
1988: Eric Boerwinkle; Gerd Utermann
Simultaneous effects of the apolipoprotein E polymorphism on apolipoprotein E, apolipoprotein B, and cholesterol metabolism.
American journal of human genetics 1988;42(1):104-12.
1987: Eric Boerwinkle; Charles F Sing
The use of measured genotype information in the analysis of quantitative phenotypes in man. III. Simultaneous estimation of the frequencies and effects of the apolipoprotein E polymorphism and residual polygenetic effects on cholesterol, betalipoprotein and triglyceride levels.
Annals of human genetics 1987;51(Pt 3):211-26.