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Rafael Solana

Research Profile

Anatomy

Physiology

Chemicals & Drugs

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Cytomegalovirus Infections

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Beatriz Sanchez-Correa; Rafael Solana; Maria Jose Arcos; Helena Bañas; Juan M Bergua; Carmen Campos; Javier García Casado; Inmaculada Gayoso; Sara Morgado; Raquel Tarazona
Cytokine profiles in acute myeloid leukemia patients at diagnosis: survival is inversely correlated with IL-6 and directly correlated with IL-10 levels.
S Cantisán; M González-Padilla; J Gutiérrez-Aroca; R Lara; M Montejo; J Redel; Antonio Rivero; Alberto Rodríguez-Benot; Rafael Solana; L Bueno; Julián Torre-Cisneros
Pretransplant interferon-γ secretion by CMV-specific CD8+ T cells informs the risk of CMV replication after transplantation.
Sara Cantisán; Rosario Lara; Miguel Montejo; Julián Torre-Cisneros; Sofía Zarraga; Rafael Solana
Impact of cytomegalovirus on early immunosenescence of CD8+ T lymphocytes after solid organ transplantation.

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2013: Beatriz Sanchez-Correa; Rafael Solana; Maria Jose Arcos; Helena Bañas; Juan M Bergua; Carmen Campos; Javier García Casado; Inmaculada Gayoso; Sara Morgado; Raquel Tarazona
Cytokine profiles in acute myeloid leukemia patients at diagnosis: survival is inversely correlated with IL-6 and directly correlated with IL-10 levels.
Cytokine 2013;61(3):885-91.
2013: S Cantisán; M González-Padilla; J Gutiérrez-Aroca; R Lara; M Montejo; J Redel; Antonio Rivero; Alberto Rodríguez-Benot; Rafael Solana; L Bueno; Julián Torre-Cisneros
Pretransplant interferon-γ secretion by CMV-specific CD8+ T cells informs the risk of CMV replication after transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2013;13(3):738-45.
2013: Sara Cantisán; Rosario Lara; Miguel Montejo; Julián Torre-Cisneros; Sofía Zarraga; Rafael Solana
Impact of cytomegalovirus on early immunosenescence of CD8+ T lymphocytes after solid organ transplantation.
The journals of gerontology. Series A, Biological sciences and medical sciences 2013;68(1):1-5.
2012: Sara Cantisán; Sara Ferrando-Martínez; Carmen Martín; Francisco Martínez; Antonio Rivero; María C Romero-Sánchez; Rafael Solana; Antonio Torres; Julián Torre-Cisneros
Role of defective thymic function in onset of ganciclovir-resistant cytomegalovirus after cord blood transplantation.
Clinical and vaccine immunology : CVI 2012;19(12):1994-8.
2012: Rafael Solana; Raquel Tarazona; Gilles Dupuis; Inmaculada Gayoso; Olivier Lesur; Tamas Fulop
Innate immunosenescence: effect of aging on cells and receptors of the innate immune system in humans.
Seminars in immunology 2012;24(5):331-41.
2011: Beatriz Sanchez-Correa; Rafael Solana; Maria Jose Arcos; Maria Luisa Bengochea; Juan M Bergua; Javier García Casado; Esther Duran; Inmaculada Gayoso; Sara Morgado; Raquel Tarazona
Human NK cells in acute myeloid leukaemia patients: analysis of NK cell-activating receptors and their ligands.
Cancer immunology, immunotherapy : CII 2011;60(8):1195-205.
2011: Sara Morgado; Beatriz Sanchez-Correa; Rafael Solana; Javier García Casado; Esther Duran; Inmaculada Gayoso; Fernando Labella; Raquel Tarazona
NK cell recognition and killing of melanoma cells is controlled by multiple activating receptor-ligand interactions.
Journal of innate immunity 2011;3(4):365-73.
2011: Inmaculada Gayoso; Sara Morgado; Alejandra Pera; Beatriz Sanchez-Correa; Corona Alonso; Carmen Campos; Javier García Casado; Raquel Tarazona; Rafael Solana
Immunosenescence of human natural killer cells.
Journal of innate immunity 2011;3(4):337-43.
2010: Sara Cantisán; Rafael Solana; Rosario Lara; Alberto Rodríguez-Benot; Jose Manuel Vaquero; Juan Gutiérrez-Aroca; Inmaculada Gayoso; Miguel Montejo; Antonio Rivero; Julián Torre-Cisneros
CD45RA expression on HCMV-specific effector memory CD8+ T cells is associated with the duration and intensity of HCMV replication after transplantation.
Clinical immunology (Orlando, Fla.) 2010;137(1):81-8.
2009: María Luisa Pita-Lopez; Inmaculada Gayoso; Olga DelaRosa; Javier García Casado; Corona Alonso; Elisa Muñoz-Gomariz; Raquel Tarazona; Rafael Solana
Effect of ageing on CMV-specific CD8 T cells from CMV seropositive healthy donors.
Immunity & ageing : I & A 2009;6():11.
2008: Anis Larbi; Claudio Franceschi; Dawn Mazzatti; Rafael Solana; Anders Wikby; Graham Pawelec
Aging of the immune system as a prognostic factor for human longevity.
Physiology (Bethesda, Md.) 2008;23():64-74.
2008: Graham Pawelec; Rafael Solana
Are cancer and ageing different sides of the same coin? Conference on Cancer and Ageing.
EMBO reports 2008;9(3):234-8.
2008: Evelyna Derhovanessian; Rafael Solana; Anis Larbi; Graham Pawelec
Immunity, ageing and cancer.
Immunity & ageing : I & A 2008;5():11.
2008: María José Pérez-Sola; Juan José Castón; Rafael Solana; Antonio Rivero; Julián Torre-Cisneros
Indirect effects of cytomegalovirus infection in solid organ transplant recipients.
Enfermedades infecciosas y microbiología clínica 2008;26(1):38-47.
2007: Sven Koch; Anis Larbi; Dennis Ozcelik; Rafael Solana; Cécile Gouttefangeas; Sebastian Attig; Anders Wikby; Jan Strindhall; Claudio Franceschi; Graham Pawelec
Cytomegalovirus infection: a driving force in human T cell immunosenescence.
Annals of the New York Academy of Sciences 2007;1114():23-35.
2007: Jose Manuel Lozano; O De la Rosa; G García-Jurado; J Luque; Rafael Solana; José María Kindelán; Antonio Rivero; José Peña
Impaired response of HIV type 1-specific CD8(+) cells from antiretroviral-treated patients.
AIDS research and human retroviruses 2007;23(10):1279-82.
2007: Esther Peralbo; Corona Alonso; Rafael Solana
Invariant NKT and NKT-like lymphocytes: two different T cell subsets that are differentially affected by ageing.
Experimental gerontology 2007;42(8):703-8.
2007: Rafael Solana; Javier García Casado; Elena Delgado; Olga DelaRosa; Juan Marín; Esther Durán; Graham Pawelec; Raquel Tarazona
Lymphocyte activation in response to melanoma: interaction of NK-associated receptors and their ligands.
Cancer immunology, immunotherapy : CII 2007;56(1):101-9.
2006: Olga DelaRosa; Graham Pawelec; Esther Peralbo; Anders Wikby; Erminia Mariani; Eugenio Mocchegiani; Raquel Tarazona; Rafael Solana
Immunological biomarkers of ageing in man: changes in both innate and adaptive immunity are associated with health and longevity.
Biogerontology 2006;7(5-6):471-81.
2006: Esther Peralbo; Olga DelaRosa; Inmaculada Gayoso; Maria L Pita; Raquel Tarazona; Rafael Solana
Decreased frequency and proliferative response of invariant Valpha24Vbeta11 natural killer T (iNKT) cells in healthy elderly.
Biogerontology 2006;7(5-6):483-92.
2006: Jose Manuel Lozano; José María Kindelán; Almudena Cabello; Rafael Gonzalez; Rafael Solana; José Peña
IL-2 increased RANTES production and CD25 expression in cultured PBMCs only from antiretroviral treated HIV-1+ patients with detectable viral loads.
International immunopharmacology 2006;6(6):1034-8.
2006: Sven Koch; Rafael Solana; Olga Dela Rosa; Graham Pawelec
Human cytomegalovirus infection and T cell immunosenescence: a mini review.
Mechanisms of ageing and development 2006;127(6):538-43.
2006: Rafael Solana; Graham Pawelec; Raquel Tarazona
Aging and innate immunity.
Immunity 2006;24(5):491-4.
2005: Javier García Casado; Rocío Soto; Olga DelaRosa; Esther Peralbo; Maria del Carmen Muñoz-Villanueva; Luis Rioja; José Peña; Rafael Solana; Raquel Tarazona
CD8 T cells expressing NK associated receptors are increased in melanoma patients and display an effector phenotype.
Cancer immunology, immunotherapy : CII 2005;54(12):1162-71.
2005: Graham Pawelec; Arne Akbar; Calogero Caruso; Rafael Solana; Beatrix Grubeck-Loebenstein; Anders Wikby
Human immunosenescence: is it infectious?
Immunological reviews 2005;205():257-68.
2004: Shalmali Chakraborty; Suvroma Gupta; Taradas Sarkar; Asim Poddar; Jose Pena; Rafael Solana; Raquel Tarazona; Bhabatarak Bhattacharyya
The B-ring substituent at C-7 of colchicine and the alpha-C-terminus of tubulin communicate through the "tail-body" interaction.
Proteins 2004;57(3):602-9.
2004: Raquel Tarazona; Javier García Casado; Rocío Soto; Olga DelaRosa; Esther Peralbo; Luis Rioja; José Peña; Rafael Solana
Expression of NK-associated receptors on cytotoxic T cells from melanoma patients: a two-edged sword?
Cancer immunology, immunotherapy : CII 2004;53(10):911-24.
2003: Almudena Cabello; Antonio Rivero; Mariá José Garcia; Jose Manuel Lozano; Julián Torre-Cisneros; Rafael González; Gema Dueñas; Maria D Galiani; Angela Camacho; Manuel Santamaria; Rafael Solana; Carmen Montero; José María Kindelán; José Peña
HAART induces the expression of HLA-G on peripheral monocytes in HIV-1 infected individuals.
Human immunology 2003;64(11):1045-9.
2003: Rafael Solana
Biogerontology research in Spain.
Experimental gerontology 2003;38(8):819-24.
2002: Raquel Tarazona; Javier García Casado; Olga DelaRosa; Julián Torre-Cisneros; José L Villanueva; Berta Sanchez; Maria D Galiani; Rafael Gonzalez; Rafael Solana; José Peña
Selective depletion of CD56(dim) NK cell subsets and maintenance of CD56(bright) NK cells in treatment-naive HIV-1-seropositive individuals.
Journal of clinical immunology 2002;22(3):176-83.
2002: Graham Pawelec; Yvonne Barnett; Ros Forsey; Daniela Frasca; Amiela Globerson; Julie McLeod; Calogero Caruso; Claudio Franceschi; Támás Fülöp; Sudhir Gupta; Erminia Mariani; Eugenio Mocchegiani; Rafael Solana
T cells and aging, January 2002 update.
Frontiers in bioscience : a journal and virtual library 2002;7():d1056-183.
2002: Francisco Borrego; Juraj Kabat; Dae-Ki Kim; Louis Lieto; Kerima Maasho; José Peña; Rafael Solana; John E Coligan
Structure and function of major histocompatibility complex (MHC) class I specific receptors expressed on human natural killer (NK) cells.
Molecular immunology 2002;38(9):637-60.
2002: Raquel Tarazona; Olga DelaRosa; Javier García Casado; Julián Torre-Cisneros; José L Villanueva; Maria D Galiani; José Peña; Rafael Solana
NK-associated receptors on CD8 T cells from treatment-naive HIV-infected individuals: defective expression of CD56.
AIDS (London, England) 2002;16(2):197-200.
2002: Graham Pawelec; Yvonne Barnett; Erminia Mariani; Rafael Solana
Human CD4+ T cell clone longevity in tissue culture: lack of influence of donor age or cell origin.
Experimental gerontology 2002;37(2-3):265-9.
2002: Olga DelaRosa; Raquel Tarazona; Javier García Casado; Corona Alonso; Belén Ostos; José Peña; Rafael Solana
Valpha24+ NKT cells are decreased in elderly humans.
Experimental gerontology 2002;37(2-3):213-7.
2002: Raquel Tarazona; Rafael Solana; Qin Ouyang; Graham Pawelec
Basic biology and clinical impact of immunosenescence.
Experimental gerontology 2002;37(2-3):183-9.
2002: Raquel Tarazona; Francisco Borrego; Maria D Galiani; Enrique Aguado; José Peña; John E Coligan; Rafael Solana
Inhibition of CD28-mediated natural cytotoxicity by KIR2DL2 does not require p56(lck) in the NK cell line YT-Indy.
Molecular immunology 2002;38(7):495-503.
2001: Taradas Sarkar; Tapas Manna; S Bhattacharyya; PK Mahapatra; Asim Poddar; Siddhartha Roy; J Pena; Rafael Solana; Raquel Tarazona; Bhabatarak Bhattacharyya
Role of the carboxy-termini of tubulin on its chaperone-like activity.
Proteins 2001;44(3):262-9.
2000: Raquel Tarazona; Olga DelaRosa; Corona Alonso; Belén Ostos; J Espejo; José Peña; Rafael Solana
Increased expression of NK cell markers on T lymphocytes in aging and chronic activation of the immune system reflects the accumulation of effector/senescent T cells.
Mechanisms of ageing and development 2000;121(1-3):77-88.
2000: Raquel Tarazona; Guillermo Lopez-LLuch; Maria D Galiani; Enrique Aguado; F Barahona; Rafael Solana; José Peña
HLA-B2702 (77-83/83-77) peptide binds to beta-tubulin on human NK cells and blocks their cytotoxic capacity.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(12):6776-82.
2000: Rafael Solana; E Mariani
NK and NK/T cells in human senescence.
Vaccine 2000;18(16):1613-20.
2000: Graham Pawelec; E Mariani; B Bradley; Rafael Solana
Longevity in vitro of human CD4+ T helper cell clones derived from young donors and elderly donors, or from progenitor cells: age-associated differences in cell surface molecule expression and cytokine secretion.
Biogerontology 2000;1(3):247-54.
1999: Rafael Solana; M C Alonso; José Peña
Natural killer cells in healthy aging.
Experimental gerontology 1999;34(3):435-43.
1999: Francisco Borrego; M J Robertson; Jerome Ritz; José Peña; Rafael Solana
CD69 is a stimulatory receptor for natural killer cell and its cytotoxic effect is blocked by CD94 inhibitory receptor.
Immunology 1999;97(1):159-65.
1999: Francisco Borrego; M C Alonso; Maria D Galiani; Julia Carracedo; Rafael Ramirez; Belén Ostos; José Peña; Rafael Solana
NK phenotypic markers and IL2 response in NK cells from elderly people.
Experimental gerontology 1999;34(2):253-65.
1999: Maria D Galiani; Enrique Aguado; Raquel Tarazona; Pilar Romero; Ignacio J Molina; M Santamaria; Rafael Solana; José Peña
Expression of killer inhibitory receptors on cytotoxic cells from HIV-1-infected individuals.
Clinical and experimental immunology 1999;115(3):472-6.
1999: Graham Pawelec; Rita B Effros; Calogero Caruso; Edmond J Remarque; Yvonne Barnett; Rafael Solana
T cells and aging (update february 1999).
Frontiers in bioscience : a journal and virtual library 1999;4():D216-69.
1998: Graham Pawelec; Rafael Solana; Edmond J Remarque; E Mariani
Impact of aging on innate immunity.
Journal of leukocyte biology 1998;64(6):703-12.
1998: Rafael Solana; Graham Pawelec
Molecular and cellular basis of immunosenescence.
Mechanisms of ageing and development 1998;102(2-3):115-29.
1998: Graham Pawelec; Edmond J Remarque; Yvonne Barnett; Rafael Solana
T cells and aging.
Frontiers in bioscience : a journal and virtual library 1998;3():d59-99.
1997: G Pawelec; Rafael Solana
Immunosenescence.
Immunology today 1997;18(11):514-6.
1997: M Valle Blázquez; I Luque; Eduardo Collantes; E Aranda; Rafael Solana; José Peña; E Muñoz
Cellular redox status influences both cytotoxic and NF-kappa B activation in natural killer cells.
Immunology 1997;90(3):455-60.
1997: Graham Pawelec; M Adibzadeh; Rafael Solana; I Beckman
The T cell in the ageing individual.
Mechanisms of ageing and development 1997;93(1-3):35-45.
1996: M Adibzadeh; E Mariani; C Bartoloni; I Beckman; G Ligthart; Edmond J Remarque; S Shall; Rafael Solana; G M Taylor; Yvonne Barnett; Graham Pawelec
Lifespans of T lymphocytes.
Mechanisms of ageing and development 1996;91(2):145-54.
1996: Inmaculada Luque; Rafael Solana; Maria D Galiani; R González; F García; J A López de Castro; José Peña
Threonine 80 on HLA-B27 confers protection against lysis by a group of natural killer clones.
European journal of immunology 1996;26(8):1974-7.
1995: JM Quesada; I Serrano; Francisco Borrego; A Martin; José Peña; Rafael Solana
Calcitriol effect on natural killer cells from hemodialyzed and normal subjects.
Calcified tissue international 1995;56(2):113-7.
1994: Francisco Borrego; A Lopez-Beltran; José Peña; Rafael Solana
Downregulation of Fc gamma receptor IIIA alpha (CD16-II) on natural killer cells induced by anti-CD16 mAb is independent of protein tyrosine kinases and protein kinase C.
Cellular immunology 1994;158(1):208-17.
1993: Francisco Borrego; José Peña; Rafael Solana
Regulation of CD69 expression on human natural killer cells: differential involvement of protein kinase C and protein tyrosine kinases.
European journal of immunology 1993;23(5):1039-43.
1993: D García-Plata; Elena Mozos; Librado Carrasco; Rafael Solana
HLA molecule expression in cutaneous squamous cell carcinomas: an immunopathological study and clinical-immunohistopathological correlations.
Histology and histopathology 1993;8(2):219-26.
1992: Rafael Ramirez; Rafael Solana; Julia Carracedo; M C Alonso; José Peña
Mechanisms involved in NK resistance induced by interferon-gamma.
Cellular immunology 1992;140(1):248-56.
1992: Rafael Solana; J Romero; C Alonso; José Peña
MHC class I antigen expression is inversely related with tumor malignancy and ras oncogene product (p21ras) levels in human breast tumors.
Invasion & metastasis 1992;12(3-4):210-7.
1991: D Garcia-Plata; Elena Mozos; MA Sierra; José Peña; Rafael Solana
HLA expression in basal cell carcinomas.
Invasion & metastasis 1991;11(3):166-73.
1990: R Serrano; Y G Yiangos; Rafael Solana; J A Sachs; J Pena
Isolation of a novel tumor protein that induces resistance to natural killer cell lysis.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(10):3516-23.
1990: José Peña; C Alonso; Rafael Solana; R Serrano; Julia Carracedo; Rafael Ramirez
Natural killer susceptibility is independent of HLA class I antigen expression on cell lines obtained from human solid tumors.
European journal of immunology 1990;20(11):2445-8.
1990: Rafael Solana; C Alonso; Rafael Ramirez; Julia Carracedo; R Serrano; Y Yiangou; José Peña
Analysis of the mechanisms involved in NK resistance induced by a new tumor factor NK-RIF.
Cellular immunology 1990;130(1):244-51.
1989: J Pena; Rafael Solana; M C Alonso; M Santamaria; R Serrano; Rafael Ramirez; Julia Carracedo
MHC class I expression on human tumour cells and their susceptibility to NK lysis.
Journal of immunogenetics 1989;16(4-5):407-12.
1989: JM Quesada; Rafael Solana; A Martin; M Santamaria; I Serrano; M E Martinez; Pedro Aljama; José Peña
The effect of calcitriol on natural killer cell activity in hemodialyzed patients.
Journal of steroid biochemistry 1989;34(1-6):423-5.