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Germán Soler

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Mireia Niso-Santano; José M Bravo-San Pedro; Rubén Gómez-Sánchez; Vicente Climent; Germán Soler; José M Fuentes; Rosa A González-Polo
ASK1 overexpression accelerates paraquat-induced autophagy via endoplasmic reticulum stress.
Rubén Gómez-Sánchez; José M Bravo-San Pedro; Mireia Niso-Santano; Germán Soler; José M Fuentes; Rosa A González-Polo
The neuroprotective effect of talipexole from paraquat-induced cell death in dopaminergic neuronal cells.
Mireia Niso-Santano; Rosa A González-Polo; José M Bravo-San Pedro; Rubén Gómez-Sánchez; Isabel Lastres-Becker; Miguel A Ortiz-Ortiz; Germán Soler; José M Morán; Antonio Cuadrado; José M Fuentes
Activation of apoptosis signal-regulating kinase 1 is a key factor in paraquat-induced cell death: modulation by the Nrf2/Trx axis.

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All Publications

2011: Mireia Niso-Santano; José M Bravo-San Pedro; Rubén Gómez-Sánchez; Vicente Climent; Germán Soler; José M Fuentes; Rosa A González-Polo
ASK1 overexpression accelerates paraquat-induced autophagy via endoplasmic reticulum stress.
Toxicological sciences : an official journal of the Society of Toxicology 2011;119(1):156-68.
2010: Rubén Gómez-Sánchez; José M Bravo-San Pedro; Mireia Niso-Santano; Germán Soler; José M Fuentes; Rosa A González-Polo
The neuroprotective effect of talipexole from paraquat-induced cell death in dopaminergic neuronal cells.
Neurotoxicology 2010;31(6):701-8.
2010: Mireia Niso-Santano; Rosa A González-Polo; José M Bravo-San Pedro; Rubén Gómez-Sánchez; Isabel Lastres-Becker; Miguel A Ortiz-Ortiz; Germán Soler; José M Morán; Antonio Cuadrado; José M Fuentes
Activation of apoptosis signal-regulating kinase 1 is a key factor in paraquat-induced cell death: modulation by the Nrf2/Trx axis.
Free radical biology & medicine 2010;48(10):1370-81.
2009: Miguel A Ortiz-Ortiz; José M Morán; Jose M Bravosanpedro; Rosa A González-Polo; Mireia Niso-Santano; Vellareddy Anantharam; Anumantha G Kanthasamy; Germán Soler; José M Fuentes
Curcumin enhances paraquat-induced apoptosis of N27 mesencephalic cells via the generation of reactive oxygen species.
Neurotoxicology 2009;30(6):1008-18.
2009: Miguel A Ortiz-Ortiz; José M Morán; Rosa A González-Polo; Mireia Niso-Santano; Germán Soler; José M Bravo-San Pedro; José M Fuentes
Nitric oxide-mediated toxicity in paraquat-exposed SH-SY5Y cells: a protective role of 7-nitroindazole.
Neurotoxicity research 2009;16(2):160-73.
2009: Rosa González-Polo; Mireia Niso-Santano; José M Morán; Miguel A Ortiz-Ortiz; José M Bravo-San Pedro; Germán Soler; José M Fuentes
Silencing DJ-1 reveals its contribution in paraquat-induced autophagy.
Journal of neurochemistry 2009;109(3):889-98.
2008: Jose M Moran; Rosa A Gonzalez-Polo; Miguel A Ortiz-Ortiz; Mireia Niso-Santano; Germán Soler; Jose M. Fuentes
Identification of genes associated with paraquat-induced toxicity in SH-SY5Y cells by PCR array focused on apoptotic pathways.
Journal of toxicology and environmental health. Part A 2008;71(22):1457-67.
2007: Rosa A González-Polo; Mireia Niso-Santano; Miguel A Ortíz-Ortíz; Ana Gómez-Martín; José M Morán; Lourdes García-Rubio; Javier Francisco-Morcillo; Concepción Zaragoza; Germán Soler; Jose M. Fuentes
Relationship between autophagy and apoptotic cell death in human neuroblastoma cells treated with paraquat: could autophagy be a "brake" in paraquat-induced apoptotic death?
Autophagy 2007;3(4):366-7.
2007: Rosa A González-Polo; Mireia Niso-Santano; Miguel A Ortíz-Ortíz; Ana Gómez-Martín; José M Morán; Lourdes García-Rubio; Javier Francisco-Morcillo; Concepción Zaragoza; Germán Soler; Jose M. Fuentes
Inhibition of paraquat-induced autophagy accelerates the apoptotic cell death in neuroblastoma SH-SY5Y cells.
Toxicological sciences : an official journal of the Society of Toxicology 2007;97(2):448-58.
2007: Pascale Kropf; David Baud; Sara E Marshall; Markus Munder; Angelina J Mosley; Jose M. Fuentes; Charles R M Bangham; Graham P Taylor; Shanti Herath; Beak-San Choi; Germán Soler; Tg Teoh; Manuel Modolell; Ingrid Müller
Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy.
European journal of immunology 2007;37(4):935-45.
2006: Mireia Niso-Santano; José M Morán; Lourdes García-Rubio; Ana Gómez-Martín; Rosa A González-Polo; Germán Soler; Jose M. Fuentes
Low concentrations of paraquat induces early activation of extracellular signal-regulated kinase 1/2, protein kinase B, and c-Jun N-terminal kinase 1/2 pathways: role of c-Jun N-terminal kinase in paraquat-induced cell death.
Toxicological sciences : an official journal of the Society of Toxicology 2006;92(2):507-15.
2006: José M Morán; Rosa A González-Polo; Germán Soler; Jose M. Fuentes
TH1/TH2 cytokines: an easy model to study gene expression in immune cells.
CBE life sciences education 2006;5(3):287-95.
2005: Vanessa Donaire; Mireia Niso; José M Morán; Lourdes García; Rosa A González-Polo; Germán Soler; Jose M. Fuentes
Heat shock proteins protect both MPP(+) and paraquat neurotoxicity.
Brain research bulletin 2005;67(6):509-14.
2005: Pascale Kropf; Jose M. Fuentes; Eva Fähnrich; Luis Arpa; Shanti Herath; Verena Weber; Germán Soler; Antonio Celada; Manuel Modolell; Ingrid Müller
Arginase and polyamine synthesis are key factors in the regulation of experimental leishmaniasis in vivo.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(8):1000-2.
2005: Markus Munder; Faustino Mollinedo; Jero Calafat; Javier Canchado; Cristina Gil-Lamaignere; Jose M. Fuentes; Claudia Luckner; Gwendolyn Doschko; Germán Soler; Klaus Eichmann; Frank-Michael C Müller; Anthony Ho; Martin Goerner; Manuel Modolell
Arginase I is constitutively expressed in human granulocytes and participates in fungicidal activity.
Blood 2005;105(6):2549-56.
2004: Rosa A González-Polo; Germán Soler; Jose M. Fuentes
MPP+: mechanism for its toxicity in cerebellar granule cells.
Molecular neurobiology 2004;30(3):253-64.
2004: Rosa A González-Polo; Andrea Rodríguez-Martín; José M Morán; Mireia Niso; Germán Soler; Jose M. Fuentes
Paraquat-induced apoptotic cell death in cerebellar granule cells.
Brain research 2004;1011(2):170-6.
2004: Rosa A González-Polo; Germán Soler; Andrea Rodríguezmartín; José M Morán; Jose M. Fuentes
Protection against MPP+ neurotoxicity in cerebellar granule cells by antioxidants.
Cell biology international 2004;28(5):373-80.
2003: Rosa A González-Polo; Germán Soler; Juan C Alonso; Andrea Rodríguez-Martín; Jose M. Fuentes
MPP(+) causes inhibition of cellular energy supply in cerebellar granule cells.
Neurotoxicology 2003;24(2):219-25.
2003: Rosa A González-Polo; Germán Soler; Alberto Alvarez; Isabel Fabregat; Jose M. Fuentes
Vitamin E blocks early events induced by 1-methyl-4-phenylpyridinium (MPP+) in cerebellar granule cells.
Journal of neurochemistry 2003;84(2):305-15.
2002: Alfonso Mora; Guadalupe Sabio; Juan C Alonso; Germán Soler; Francisco Centeno
Different dependence of lithium and valproate on PI3K/PKB pathway.
Bipolar disorders 2002;4(3):195-200.
2002: Alfonso Mora; Guadalupe Sabio; Ana María Risco; Ana Cuenda; Juan C Alonso; Germán Soler; Francisco Centeno
Lithium blocks the PKB and GSK3 dephosphorylation induced by ceramide through protein phosphatase-2A.
Cellular signalling 2002;14(6):557-62.
2002: Rangel M del Ara; Rosa A González-Polo; A Caro; E del Amo; L Palomo; E Hernández; Germán Soler; Jose M. Fuentes
Diagnostic performance of arginase activity in colorectal cancer.
Clinical and experimental medicine 2002;2(1):53-7.
2001: Rosa A González-Polo; A Mora; N Clemente; Guadalupe Sabio; Francisco Centeno; Germán Soler; Jose M. Fuentes
Mechanisms of MPP(+) incorporation into cerebellar granule cells.
Brain research bulletin 2001;56(2):119-23.
2001: Guadalupe Sabio; Alfonso Mora; M A Rangel; A Quesada; C F Marcos; Juan C Alonso; Germán Soler; Francisco Centeno
Glu-256 is a main structural determinant for oligomerisation of human arginase I.
FEBS letters 2001;501(2-3):161-5.
2001: Alfonso Mora; Guadalupe Sabio; Rosa A González-Polo; Ana Cuenda; Dario R Alessi; Juan C Alonso; Jose M. Fuentes; Germán Soler; Francisco Centeno
Lithium inhibits caspase 3 activation and dephosphorylation of PKB and GSK3 induced by K+ deprivation in cerebellar granule cells.
Journal of neurochemistry 2001;78(1):199-206.
2000: Alfonso Mora; M del Ara Rangel; Jose M. Fuentes; Germán Soler; Francisco Centeno
Implications of the S-shaped domain in the quaternary structure of human arginase.
Biochimica et biophysica acta 2000;1476(2):181-90.
1999: Alfonso Mora; Rosa A González-Polo; Jose M. Fuentes; Germán Soler; Francisco Centeno
Different mechanisms of protection against apoptosis by valproate and Li+.
European journal of biochemistry / FEBS 1999;266(3):886-91.
1999: Markus Munder; Klaus Eichmann; José M Morán; Francisco Centeno; Germán Soler; Manuel Modolell
Th1/Th2-regulated expression of arginase isoforms in murine macrophages and dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(7):3771-7.
1998: Francisco Centeno; Alfonso Mora; Jose M. Fuentes; Germán Soler; Enrique Claro
Partial lithium-associated protection against apoptosis induced by C2-ceramide in cerebellar granule neurons.
Neuroreport 1998;9(18):4199-203.
1997: I M Corraliza; Manuel Modolell; E Ferber; Germán Soler
Involvement of protein kinase A in the induction of arginase in murine bone marrow-derived macrophages.
Biochimica et biophysica acta 1997;1334(2-3):123-8.
1997: Manuel Modolell; Klaus Eichmann; Germán Soler
Oxidation of N(G)-hydroxyl-L-arginine to nitric oxide mediated by respiratory burst: an alternative pathway to NO synthesis.
FEBS letters 1997;401(2-3):123-6.
1997: C A Pereira; Germán Soler; Manuel Modolell
Anti-MHV3 state induced by IFN gamma in macrophages is not related to arginine metabolism.
Archives of virology 1997;142(10):2001-10.
1995: Manuel Modolell; I M Corraliza; F Link; Germán Soler; Klaus Eichmann
Reciprocal regulation of the nitric oxide synthase/arginase balance in mouse bone marrow-derived macrophages by TH1 and TH2 cytokines.
European journal of immunology 1995;25(4):1101-4.
1995: I M Corraliza; Germán Soler; Klaus Eichmann; Manuel Modolell
Arginase induction by suppressors of nitric oxide synthesis (IL-4, IL-10 and PGE2) in murine bone-marrow-derived macrophages.
Biochemical and biophysical research communications 1995;206(2):667-73.
1994: I M Corraliza; María Luisa Campo; Germán Soler; Manuel Modolell
Determination of arginase activity in macrophages: a micromethod.
Journal of immunological methods 1994;174(1-2):231-5.
1994: Jose M. Fuentes; María Luisa Campo; Germán Soler
Kinetics and inhibition by some aminoacids of lactating rat mammary gland arginase.
Archives internationales de physiologie, de biochimie et de biophysique 1994;102(5):255-8.
1994: Jose M. Fuentes; M R Pascual; Gines M Salido; Germán Soler; juan antonio madrid
Oscillations in rat liver cytosolic enzyme activities of the urea cycle.
Archives internationales de physiologie, de biochimie et de biophysique 1994;102(5):237-41.
1994: Amalia Diez; Jose M. Fuentes; F Prada; María Luisa Campo; Germán Soler
Immunological identity of the two different molecular mass constitutive subunits of liver arginase.
Biological chemistry Hoppe-Seyler 1994;375(8):537-41.
1994: Jose M. Fuentes; María Luisa Campo; Germán Soler
Kinetics of manganese reconstitution and thiol group exposition in dialyzed rat mammary gland arginase.
The International journal of biochemistry 1994;26(5):653-9.
1993: I M Corraliza; María Luisa Campo; Jose M. Fuentes; S Campos-Portuguez; Germán Soler
Parallel induction of nitric oxide and glucose-6-phosphate dehydrogenase in activated bone marrow derived macrophages.
Biochemical and biophysical research communications 1993;196(1):342-7.
1992: A M Díez; María Luisa Campo; Germán Soler
Trypsin digestion of arginase: evidence for a stable conformation manganese directed.
The International journal of biochemistry 1992;24(12):1925-32.
1992: José M Bautista; Jose M. Fuentes; Amalia Diez; Carlos Gutiérrez-Merino; Germán Soler
Unfolding and trypsin inactivation studies reveal a conformation drift of glucose-6-phosphate dehydrogenase upon binding of NADP.
Biochimica et biophysica acta 1992;1122(1):99-106.
1992: María Luisa Campo; Jose M. Fuentes; Germán Soler
An arginine regulated gamma-guanidobutyrate ureahydrolase from tench liver (Tinca tinca L.).
Archives internationales de physiologie, de biochimie et de biophysique 1992;100(1):55-60.
1991: Jose M. Fuentes; María Luisa Campo; Germán Soler
Physico-chemical properties of hepatocyte plasma-membrane-bound arginase.
Archives internationales de physiologie, de biochimie et de biophysique 1991;99(6):413-7.
1990: Amalia Diez; María Luisa Campo; Germán Soler
Properties of arginase immobilized in a fibrin clot.
Biotechnology and applied biochemistry 1990;12(3):237-44.
1988: José M Bautista; Amando Garrido-Pertierra; Germán Soler
Glucose-6-phosphate dehydrogenase from Dicentrarchus labrax liver: kinetic mechanism and kinetics of NADPH inhibition.
Biochimica et biophysica acta 1988;967(3):354-63.
1988: Germán Soler; José M Bautista; juan antonio madrid; Gines M Salido
Circadian rhythms in enzymatic activity of rat liver arginase and glucose 6-phosphate dehydrogenase.
Chronobiologia 1988;15(3):205-12.