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Laura Solforosi

Research Profile

Chemicals & Drugs

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Neutralization Tests

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Protein Conformation

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Publications

TOP 3
Laura Solforosi; Massimo Clementi; Nicasio Mancini; Michela Milani; Roberto Burioni
A closer look at prion strains: characterization and important implications.
Roberta Antonia Diotti; Nicasio Mancini; Giuseppe Andrea Sautto; Laura Solforosi; Massimo Clementi; Roberto Burioni
Neutralization activity and kinetics of two broad-range human monoclonal IgG1 derived from recombinant Fab fragments and directed against Hepatitis C virus E2 glycoprotein.
Giuseppe Sautto; Laura Solforosi; Massimo Clementi; Roberta A Diotti; Nicasio Mancini; Roberto Burioni
Anti-hepatitis C virus E2 (HCV/E2) glycoprotein monoclonal antibodies and neutralization interference.

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All Publications

2013: Laura Solforosi; Massimo Clementi; Nicasio Mancini; Michela Milani; Roberto Burioni
A closer look at prion strains: characterization and important implications.
Prion 2013;7(2):99-108.
2012: Roberta Antonia Diotti; Nicasio Mancini; Giuseppe Andrea Sautto; Laura Solforosi; Massimo Clementi; Roberto Burioni
Neutralization activity and kinetics of two broad-range human monoclonal IgG1 derived from recombinant Fab fragments and directed against Hepatitis C virus E2 glycoprotein.
The new microbiologica 2012;35(4):475-9.
2012: Giuseppe Sautto; Laura Solforosi; Massimo Clementi; Roberta A Diotti; Nicasio Mancini; Roberto Burioni
Anti-hepatitis C virus E2 (HCV/E2) glycoprotein monoclonal antibodies and neutralization interference.
Antiviral research 2012;96(1):82-9.
2012: Mancini Nicasio; Giuseppe Sautto; Laura Solforosi; Matteo Castelli; Massimo Clementi; Nicola Clementi; Elena Criscuolo; Roberta A Diotti; Roberto Burioni
Neutralization interfering antibodies: a "novel" example of humoral immune dysfunction facilitating viral escape?
Viruses 2012;4(9):1731-52.
2012: Laura Solforosi; Filippo Canducci; Massimo Clementi; Nicola Clementi; Roberta Antonia Diotti; Nicasio Mancini; Giuseppe Andrea Sautto; Roberto Burioni
A phage display vector optimized for the generation of human antibody combinatorial libraries and the molecular cloning of monoclonal antibody fragments.
The new microbiologica 2012;35(3):289-94.
2012: Nicola Clementi; Nicasio Mancini; Laura Solforosi; Matteo Castelli; Massimo Clementi; Roberto Burioni
Phage Display-based Strategies for Cloning and Optimization of Monoclonal Antibodies Directed against Human Pathogens.
International journal of molecular sciences 2012;13(7):8273-92.
2012: Giuseppe Sautto; Laura Solforosi; Massimo Clementi; Roberta A Diotti; Nicasio Mancini; Roberto Burioni
HCV proteins and immunoglobulin variable gene (IgV) subfamilies in HCV-induced type II mixed cryoglobulinemia: a concurrent pathogenetic role.
Clinical & developmental immunology 2012;2012():705013.
2012: Donata DE MARCO; Larisa V Gubareva; Nicasio Mancini; Vasiliy Mishin; Guisella J Moreno; Laura Solforosi; Xiangjie Sun; Terrence M Tumpey; Massimo Clementi; Nicola Clementi; Roberto Burioni
A non-VH1-69 heterosubtypic neutralizing human monoclonal antibody protects mice against H1N1 and H5N1 viruses.
PloS one 2012;7(4):e34415.
2011: Nicasio Mancini; Laura Solforosi; Massimo Clementi; Nicola Clementi; Donata DE MARCO; Roberto Burioni
A potential role for monoclonal antibodies in prophylactic and therapeutic treatment of influenza.
Antiviral research 2011;92(1):15-26.
2011: Justin T Cruite; Gil C Abalos; Anne Bellon; Laura Solforosi
Histidines in the octapeptide repeat of PrPC react with PrPSc at an acidic pH.
Biochemistry 2011;50(10):1618-23.
2008: Gil Abalos; Justin T Cruite; Anne Bellon; Saskia Hemmers; Junya Akagi; James A Mastrianni; R Anthony Williamson; Laura Solforosi
Identifying key components of the PrPC-PrPSc replicative interface.
The Journal of biological chemistry 2008;283(49):34021-8.
2008: Matthew J Trifilo; Manuel Sanchez-Alavez; Laura Solforosi; Joie Trifilo; Stefan Kunz; Dorian B McGavern; Michael B A Oldstone
Scrapie-induced defects in learning and memory of transgenic mice expressing anchorless prion protein are associated with alterations in the gamma aminobutyric acid-ergic pathway.
Journal of virology 2008;82(20):9890-9.
2008: Emiliano Biasini; M Esa Seegulam; Brianna N Patti; Laura Solforosi; Andrea Z Medrano; Heather M Christensen; Assunta Senatore; Roberto Chiesa; R Anthony Williamson; David A Harris
Non-infectious aggregates of the prion protein react with several PrPSc-directed antibodies.
Journal of neurochemistry 2008;105(6):2190-204.
2007: Laura Solforosi; Anne Bellon; Monica Schaller; Justin T Cruite; Gil Abalos; R Anthony Williamson
Toward molecular dissection of PrPC-PrPSc interactions.
The Journal of biological chemistry 2007;282(10):7465-71.
2004: Gianluca Moroncini; Nnennaya Kanu; Laura Solforosi; Gil Abalos; Glenn C Telling; Mark W Head; James Ironside; Jeremy P Brockes; Dennis R Burton; R Anthony Williamson
Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(28):10404-9.
2004: Laura Solforosi; José R Criado; Dorian B McGavern; Sebastian A Wirz; Manuel Sánchez-Alavez; Shuei Sugama; Lorraine A DeGiorgio; Bruce T Volpe; Erika Wiseman; Gil Abalos; Eliezer Masliah; Donald Gilden; Michael B A Oldstone; Bruno Conti; R Anthony Williamson
Cross-linking cellular prion protein triggers neuronal apoptosis in vivo.
Science (New York, N.Y.) 2004;303(5663):1514-6.
2003: Estelle Leclerc; David Peretz; Haydn Ball; Laura Solforosi; Giuseppe Legname; Jiri G Safar; Ana Serban; Stanley B Prusiner; Dennis R Burton; R Anthony Williamson
Conformation of PrP(C) on the cell surface as probed by antibodies.
Journal of molecular biology 2003;326(2):475-83.
2002: Jiri G Safar; Michael Scott; Jeff Monaghan; Camille Deering; Svetlana Didorenko; Julie Vergara; Haydn Ball; Giuseppe Legname; Estelle Leclerc; Laura Solforosi; Hana Serban; Darlene Groth; Dennis R Burton; Stanley B Prusiner; R Anthony Williamson
Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice.
Nature biotechnology 2002;20(11):1147-50.