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Beka Solomon

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Publications

TOP 3
Inna Rabinovich-Nikitin; Idan S Rakover; Maria Becker; Beka Solomon
Beneficial effect of antibodies against β- secretase cleavage site of APP on Alzheimer's-like pathology in triple-transgenic mice.
Polina Rabinovich-Toidman; Beika Barbiro; Maria Becker; Beka Solomon
Inhibition of amyloid precursor protein beta-secretase cleavage site affects survival and motor functions of amyotrophic lateral sclerosis transgenic mice.
Beka Solomon; Dan Frenkel
Immunotherapy for Alzheimer's disease.

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All Publications

2012: Inna Rabinovich-Nikitin; Idan S Rakover; Maria Becker; Beka Solomon
Beneficial effect of antibodies against β- secretase cleavage site of APP on Alzheimer's-like pathology in triple-transgenic mice.
PloS one 2012;7(10):e46650.
2012: Polina Rabinovich-Toidman; Beika Barbiro; Maria Becker; Beka Solomon
Inhibition of amyloid precursor protein beta-secretase cleavage site affects survival and motor functions of amyotrophic lateral sclerosis transgenic mice.
Neuro-degenerative diseases 2012;10(1-4):30-3.
2010: Beka Solomon; Dan Frenkel
Immunotherapy for Alzheimer's disease.
Neuropharmacology 2010;59(4-5):303-9.
2010: Idan S Rakover; Natalia Zabavnik; Rela Kopel; Miri Paz-Rozner; Beka Solomon
Antigen-specific therapy of EAE via intranasal delivery of filamentous phage displaying a myelin immunodominant epitope.
Journal of neuroimmunology 2010;225(1-2):68-76.
2010: Sara Orgad; Hemi Dimant; Eyal Dor-On; Ronit Azriel-Rosenfeld; Itai Benhar; Beka Solomon
TAR1, a human anti-p53 single-chain antibody, restores tumor suppressor function to mutant p53 variants.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2010;33(2):146-54.
2010: Michal Arbel-Ornath; Maria Becker; Polina Rabinovich-Toidman; Myra Gartner; Beka Solomon
Immunomodulation of AβPP processing alleviates amyloid-β-related pathology in Alzheimer's disease transgenic mice.
Journal of Alzheimer's disease : JAD 2010;22(2):469-82.
2010: Hemi Dimant; Beka Solomon
Filamentous phages reduce alpha-synuclein oligomerization in the membrane fraction of SH-SY5Y cells.
Neuro-degenerative diseases 2010;7(1-3):203-5.
2009: Hemi Dimant; Noa Sharon; Beka Solomon
Modulation effect of filamentous phage on alpha-synuclein aggregation.
Biochemical and biophysical research communications 2009;383(4):491-6.
2009: Beka Solomon
Immunotherapeutic strategies for Alzheimer's disease treatment.
TheScientificWorldJournal 2009;9():909-19.
2008: Beka Solomon
Filamentous bacteriophage as a novel therapeutic tool for Alzheimer's disease treatment.
Journal of Alzheimer's disease : JAD 2008;15(2):193-8.
2008: Beka Solomon
Immunological approaches for amyloid-beta clearance toward treatment for Alzheimer's disease.
Rejuvenation research 2008;11(2):349-57.
2007: Michal Arbel; Beka Solomon
Immunotherapy for Alzheimer's disease: attacking amyloid-beta from the inside.
Trends in immunology 2007;28(12):511-3.
2007: Michal Arbel; Beka Solomon
A novel immunotherapy for Alzheimer's disease: antibodies against the beta-secretase cleavage site of APP.
Current Alzheimer research 2007;4(4):437-45.
2007: Beka Solomon
Antibody-mediated immunotherapy for Alzheimer's disease.
Current opinion in investigational drugs (London, England : 2000) 2007;8(7):519-24.
2007: Beka Solomon
Clinical immunologic approaches for the treatment of Alzheimer's disease.
Expert opinion on investigational drugs 2007;16(6):819-28.
2007: Beka Solomon
Beta-amyloidbased immunotherapy as a treatment of Alzheimers disease.
Drugs of today (Barcelona, Spain : 1998) 2007;43(5):333-42.
2007: Beka Solomon
A neuroimmunologist's perspective on Alzheimer's disease therapy.
Expert review of neurotherapeutics 2007;7(5):439-41.
2007: Beka Solomon
Active immunization against Alzheimer's beta-amyloid peptide using phage display technology.
Vaccine 2007;25(16):3053-6.
2007: Beka Solomon
Intravenous immunoglobulin and Alzheimer's disease immunotherapy.
Current opinion in molecular therapeutics 2007;9(1):79-85.
2007: Maria Becker; Vered Lavie; Beka Solomon
Stimulation of endogenous neurogenesis by anti-EFRH immunization in a transgenic mouse model of Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(5):1691-6.
2007: Idan Rakover; Michal Arbel; Beka Solomon
Immunotherapy against APP beta-secretase cleavage site improves cognitive function and reduces neuroinflammation in Tg2576 mice without a significant effect on brain abeta levels.
Neuro-degenerative diseases 2007;4(5):392-402.
2006: Gili Istrin; Eran Bosis; Beka Solomon
Intravenous immunoglobulin enhances the clearance of fibrillar amyloid-beta peptide.
Journal of neuroscience research 2006;84(2):434-43.
2006: Beka Solomon
Alzheimer's disease immunotherapy: from in vitro amyloid immunomodulation to in vivo vaccination.
Journal of Alzheimer's disease : JAD 2006;9(3 Suppl):433-8.
2005: Sara Orgad; Naomi Goldfinger; Gerald Cohen; Varda Rotter; Beka Solomon
Single chain antibody against the common epitope of mutant p53 restores wild-type activity to mutant p53 protein.
FEBS letters 2005;579(25):5609-15.
2005: Sabina Rebe; Beka Solomon
Deglycosylation of anti-beta amyloid antibodies inhibits microglia activation in BV-2 cellular model.
American journal of Alzheimer's disease and other dementias 2005;20(5):303-13.
2005: Michal Arbel; Iftach Yacoby; Beka Solomon
Inhibition of amyloid precursor protein processing by beta-secretase through site-directed antibodies.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(21):7718-23.
2005: Beka Solomon
Generation of anti-beta-amyloid antibodies via phage display technology towards Alzheimer's disease vaccination.
Vaccine 2005;23(17-18):2327-30.
2004: Beka Solomon
Alzheimer's disease and immunotherapy.
Current Alzheimer research 2004;1(3):149-63.
2004: Dan Frenkel; Mally Dori; Beka Solomon
Generation of anti-beta-amyloid antibodies via phage display technology.
Vaccine 2004;22(19):2505-8.
2004: Vered Lavie; Maria Becker; Rachel Cohen-Kupiec; Iftach Yacoby; Rela Koppel; Manuela Wedenig; Birgit Hutter-Paier; Beka Solomon
EFRH-phage immunization of Alzheimer's disease animal model improves behavioral performance in Morris water maze trials.
Journal of molecular neuroscience : MN 2004;24(1):105-13.
2003: Michal Arbel; Vered Lavie; Beka Solomon
Generation of antibodies against prion protein in wild-type mice via helix 1 peptide immunization.
Journal of neuroimmunology 2003;144(1-2):38-45.
2003: Dan Frenkel; Ilse Dewachter; Fred Van Leuven; Beka Solomon
Reduction of beta-amyloid plaques in brain of transgenic mouse model of Alzheimer's disease by EFRH-phage immunization.
Vaccine 2003;21(11-12):1060-5.
2003: Beka Solomon
Immunological approach for the treatment of Alzheimer's disease.
Journal of molecular neuroscience : MN 2003;20(3):283-6.
2002: Beka Solomon
Immunological approaches as therapy for Alzheimer's disease.
Expert opinion on biological therapy 2002;2(8):907-17.
2002: Beka Solomon
Anti-aggregating antibodies, a new approach towards treatment of conformational diseases.
Current medicinal chemistry 2002;9(19):1737-49.
2002: Weihong Pan; Beka Solomon; Lawrence M Maness; Abba J Kastin
Antibodies to beta-amyloid decrease the blood-to-brain transfer of beta-amyloid peptide.
Experimental biology and medicine (Maywood, N.J.) 2002;227(8):609-15.
2002: Dan Frenkel; Beka Solomon
Filamentous phage as vector-mediated antibody delivery to the brain.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5675-9.
2002: Beka Solomon
Towards Alzheimer's disease vaccination.
Mini reviews in medicinal chemistry 2002;2(1):85-92.
2002: Beka Solomon; D Frenkel
Generation and brain delivery of anti-aggregating antibodies against beta-amyloid plaques using phage display technology.
Journal of neural transmission. Supplementum 2002;(62):321-5.
2001: E Hanan; S A Priola; Beka Solomon
Antiaggregating antibody raised against human PrP 106-126 recognizes pathological and normal isoforms of the whole prion protein.
Cellular and molecular neurobiology 2001;21(6):693-703.
2001: Yaakov Levy; E Hanan; Beka Solomon; Oren M Becker
Helix-coil transition of PrP106-126: molecular dynamic study.
Proteins 2001;45(4):382-96.
2001: Dmitry Govorko; G Cohen; Beka Solomon
Single-chain antibody against the common epitope of mutant p53: isolation and intracytosolic expression in mammalian cells.
Journal of immunological methods 2001;258(1-2):169-81.
2001: Beka Solomon
Immunotherapeutic strategies for prevention and treatment of Alzheimer's disease.
DNA and cell biology 2001;20(11):697-703.
2001: X Li; Beka Solomon
Zinc-mediated thermal stabilization of carboxypeptidase A.
Biomolecular engineering 2001;18(4):179-83.
2001: Rela Koppel; Beka Solomon
IgM detection via selective recognition by mannose-binding protein.
Journal of biochemical and biophysical methods 2001;49(1-3):641-7.
2001: Dan Frenkel; Beka Solomon
Towards Alzheimer's beta-amyloid vaccination.
Biologicals : journal of the International Association of Biological Standardization 2001;29(3-4):243-7.
2001: Beka Solomon; Rela Koppel; Joseph Jossiphov
Immunostaining of calmodulin and aluminium in Alzheimer's disease-affected brains.
Brain research bulletin 2001;55(2):253-6.
2001: Dan Frenkel; Naam Kariv; Beka Solomon
Generation of auto-antibodies towards Alzheimer's disease vaccination.
Vaccine 2001;19(17-19):2615-9.
2001: E Hanan; O Goren; M Eshkenazy; Beka Solomon
Immunomodulation of the human prion peptide 106-126 aggregation.
Biochemical and biophysical research communications 2001;280(1):115-20.
2000: Ruth A Steingart; Beka Solomon; Douglas E Brenneman; Mati Fridkin; Illana Gozes
VIP and peptides related to activity-dependent neurotrophic factor protect PC12 cells against oxidative stress.
Journal of molecular neuroscience : MN 2000;15(3):137-45.
2000: Dan Frenkel; Odelia Katz; Beka Solomon
Immunization against Alzheimer's beta -amyloid plaques via EFRH phage administration.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(21):11455-9.
2000: Beka Solomon; D Frenkel
Vaccination for the prevention and treatment of Alzheimer's disease.
Drugs of today (Barcelona, Spain : 1998) 2000;36(9):655-63.
2000: Dan Frenkel; Beka Solomon; Itai Benhar
Modulation of Alzheimer's beta-amyloid neurotoxicity by site-directed single-chain antibody.
Journal of neuroimmunology 2000;106(1-2):23-31.
1999: Beka Solomon; A Taraboulos; Ephraim Katchalski-Katzir
International Workshop on Conformational Diseases, Dead Sea, Israel, November 8-12, 1998 (sponsored by the Center for the Study of Emerging Diseases (CSED)).
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1999;6(3):225-8.
1999: Dan Frenkel; Moshe Balass; Ephraim Katchalski-Katzir; Beka Solomon
High affinity binding of monoclonal antibodies to the sequential epitope EFRH of beta-amyloid peptide is essential for modulation of fibrillar aggregation.
Journal of neuroimmunology 1999;95(1-2):136-42.
1998: R Levi; T Wolf; Gideon Fleminger; Beka Solomon
Immuno-detection of aluminium and aluminium induced conformational changes in calmodulin--implications in Alzheimer's disease.
Molecular and cellular biochemistry 1998;189(1-2):41-6.
1998: Dan Frenkel; Moshe Balass; Beka Solomon
N-terminal EFRH sequence of Alzheimer's beta-amyloid peptide represents the epitope of its anti-aggregating antibodies.
Journal of neuroimmunology 1998;88(1-2):85-90.
1998: R Levy; L Shohat; Beka Solomon
Specificity of an anti-aluminium monoclonal antibody toward free and protein-bound aluminium.
Journal of inorganic biochemistry 1998;69(3):159-63.
1998: T Wolf; Beka Solomon; Dmitri Ivnitski; Judith Rishpon; Gideon Fleminger
Interactions of calmodulin with metal ions and with its target proteins revealed by conformation-sensitive monoclonal antibodies.
Journal of molecular recognition : JMR 1998;11(1-6):14-9.
1997: X Li; Beka Solomon
Thermal stabilization of carboxypeptidase A as a function of pH and ionic milieu.
Biochemistry and molecular biology international 1997;43(3):601-11.
1997: Beka Solomon; Rela Koppel; D Frankel; E Hanan-Aharon
Disaggregation of Alzheimer beta-amyloid by site-directed mAb.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):4109-12.
1996: T Katzav-Gozansky; E Hanan; Beka Solomon
Effect of monoclonal antibodies in preventing carboxypeptidase A aggregation.
Biotechnology and applied biochemistry 1996;23 ( Pt 3)():227-30.
1996: Beka Solomon; R Koppel; E Hanan; T Katzav
Monoclonal antibodies inhibit in vitro fibrillar aggregation of the Alzheimer beta-amyloid peptide.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(1):452-5.
1995: E Ron; A Freeman; Beka Solomon
Stabilization and surface modification of monoclonal antibodies by 'bi-layer encagement'.
Journal of immunological methods 1995;180(2):237-45.
1995: Beka Solomon; F Schwartz
Chaperone-like effect of monoclonal antibodies on refolding of heat-denatured carboxypeptidase A.
Journal of molecular recognition : JMR 1995;8(1-2):72-6.
1995: T Wolf; Gideon Fleminger; Beka Solomon
Functional conformations of calmodulin: I. Preparation and characterization of a conformational specific anti-bovine calmodulin monoclonal antibody.
Journal of molecular recognition : JMR 1995;8(1-2):67-71.
1994: R Koppel; M Litvak; Beka Solomon
Affinity purification of a mannose-binding protein, a sensitive tool in the diagnostics of IgM, via site-directed phosphorylated mannan bound to alumina.
Journal of chromatography. B, Biomedical applications 1994;662(2):191-6.
1993: Beka Solomon; S Schmitt; F Schwartz; A Levi; Gideon Fleminger
Eupergit C-coated membranes as solid support for a sensitive immunoassay of human albumin.
Journal of immunological methods 1993;157(1-2):209-15.
1992: Beka Solomon; Gideon Fleminger; F Schwartz; Ram Doolman; B A Sela
Microalbuminuria immunoassay based on antibodies covalently conjugated to Eupergit C-coated beads.
Diabetes care 1992;15(11):1451-4.
1992: Gideon Fleminger; T Neufeld; M Star-Weinstock; M Litvak; Beka Solomon
Calcium-modulated conformational affinity chromatography. Application to the purification of calmodulin and S100 proteins.
Journal of chromatography 1992;597(1-2):263-70.
1992: Beka Solomon; O Raviv; E Leibman; Gideon Fleminger
Affinity purification of antibodies using immobilized FB domain of protein A.
Journal of chromatography 1992;597(1-2):257-62.
1991: Beka Solomon; N Balas
Thermostabilization of carboxypeptidase A by interaction with its monoclonal antibodies.
Biotechnology and applied biochemistry 1991;14(2):202-11.
1990: Gideon Fleminger; T Wolf; Eran Hadas; Beka Solomon
Eupergit C as a carrier for high-performance liquid chromatographic-based immunopurification of antigens and antibodies.
Journal of chromatography 1990;510():311-9.
1990: Gideon Fleminger; Beka Solomon; T Wolf; Eran Hadas
Effect of polyethylene glycol on the non-specific adsorption of proteins to Eupergit C and agarose.
Journal of chromatography 1990;510():271-9.
1990: Beka Solomon; R Koppel; F Schwartz; Gideon Fleminger
Enzymic oxidation of monoclonal antibodies by soluble and immobilized bifunctional enzyme complexes.
Journal of chromatography 1990;510():321-9.
1990: Gideon Fleminger; Eran Hadas; T Wolf; Beka Solomon
Oriented immobilization of periodate-oxidized monoclonal antibodies on amino and hydrazide derivatives of Eupergit C.
Applied biochemistry and biotechnology 1990;23(2):123-37.
1990: F Schwartz; Eran Hadas; M Harnik; Beka Solomon
Enzyme-linked immunosorbent assays for determination of plasma aldosterone using highly specific polyclonal antibodies.
Journal of immunoassay 1990;11(2):215-34.
1990: Beka Solomon; K Larsen; J F Riordan
A neoisoform of carboxypeptidase A produced by a single proteolytic cleavage.
Annals of the New York Academy of Sciences 1990;613():594-9.
1989: Beka Solomon; R Koppel; D Kenett; Gideon Fleminger
Localization of a highly immunogenic region of carboxypeptidase A recognized by three different monoclonal antibodies and their use in the detection of subtle conformational alterations in this enzyme region.
Biochemistry 1989;28(3):1235-41.
1987: Beka Solomon; Z Hollander; R Koppel; Ephraim Katchalski-Katzir
Use of monoclonal antibodies for the preparation of highly active immobilized enzymes.
Methods in enzymology 1987;135():160-70.
1987: Beka Solomon; R Koppel
Enzyme immobilization via monoclonal antibodies.
Annals of the New York Academy of Sciences 1987;501():463-7.
1986: Beka Solomon; R Koppel; G Pines; E Katchalski-Katzir
Enzyme immobilization via monoclonal antibodies I. Preparation of a highly active immobilized carboxypeptidase A.
Biotechnology and bioengineering 1986;28(8):1213-21.
1984: Beka Solomon; N Moav; G Pines; Ephraim Katchalski-Katzir
Interaction of carboxypeptidase A with monoclonal antibodies.
Molecular immunology 1984;21(1):1-11.