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Wolfgang Sommergruber

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Stefan Kastner; Simon Keuerleber; Michael Freissmuth; Christina Glöckel; Tilman Voss; Wolfgang Sommergruber
Expression of G protein-coupled receptor 19 in human lung cancer cells is triggered by entry into S-phase and supports G(2)-M cell-cycle progression.
Frank Hilberg; Gerald J Roth; Martin Krssak; Susanna Kautschitsch; Wolfgang Sommergruber; Ulrike Tontsch-Grunt; Pilar Garin-Chesa; Gerd Bader; Andreas Zoephel; Jens Quant; Armin Heckel; Wolfgang J Rettig
BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy.
Sebastian Glatt; Daniel Halbauer; Stefan Heindl; Andreas Wernitznig; Daniela Kozina; Kuan-Chung Su; Christina Puri; Pilar Garin-Chesa; Wolfgang Sommergruber
hGPR87 contributes to viability of human tumor cells.

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All Publications

2012: Stefan Kastner; Simon Keuerleber; Michael Freissmuth; Christina Glöckel; Tilman Voss; Wolfgang Sommergruber
Expression of G protein-coupled receptor 19 in human lung cancer cells is triggered by entry into S-phase and supports G(2)-M cell-cycle progression.
Molecular cancer research : MCR 2012;10(10):1343-58.
2008: Frank Hilberg; Gerald J Roth; Martin Krssak; Susanna Kautschitsch; Wolfgang Sommergruber; Ulrike Tontsch-Grunt; Pilar Garin-Chesa; Gerd Bader; Andreas Zoephel; Jens Quant; Armin Heckel; Wolfgang J Rettig
BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy.
Cancer research 2008;68(12):4774-82.
2008: Sebastian Glatt; Daniel Halbauer; Stefan Heindl; Andreas Wernitznig; Daniela Kozina; Kuan-Chung Su; Christina Puri; Pilar Garin-Chesa; Wolfgang Sommergruber
hGPR87 contributes to viability of human tumor cells.
International journal of cancer. Journal international du cancer 2008;122(9):2008-16.
2007: Kurt Aigner; Brigitta Dampier; L Descovich; Mario Mikula; A Sultan; Martin Schreiber; Wolfgang Mikulits; Thomas Brabletz; D Strand; P Obrist; Wolfgang Sommergruber; Norbert Schweifer; A Wernitznig; Hartmut Beug; Roland Foisner; Andreas Eger
The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity.
Oncogene 2007;26(49):6979-88.
2007: Kurt Aigner; Luise Descovich; Mario Mikula; Aneesa Sultan; Brigitta Dampier; Stefan Bonné; Frans van Roy; Wolfgang Mikulits; Martin Schreiber; Thomas Brabletz; Wolfgang Sommergruber; Norbert Schweifer; Andreas Wernitznig; Hartmut Beug; Roland Foisner; Andreas Eger
The transcription factor ZEB1 (deltaEF1) represses Plakophilin 3 during human cancer progression.
FEBS letters 2007;581(8):1617-24.
2007: Michaela Petz; Daniela Kozina; Heidemarie Huber; Tanja Siwiec; Joachim Seipelt; Wolfgang Sommergruber; Wolfgang Mikulits
The leader region of Laminin B1 mRNA confers cap-independent translation.
Nucleic acids research 2007;35(8):2473-82.
2007: Margit Pacher; Michael J Seewald; Mario Mikula; Susanne Oehler; Maurice Mogg; Ursula Vinatzer; Andreas Eger; Norbert Schweifer; Roland Varecka; Wolfgang Sommergruber; Wolfgang Mikulits; Martin Schreiber
Impact of constitutive IGF1/IGF2 stimulation on the transcriptional program of human breast cancer cells.
Carcinogenesis 2007;28(1):49-59.
2006: Ingvar Ferby; Markus Reschke; Oliver Kudlacek; Pjotr Knyazev; Guido Pantè; Kerstin Amann; Wolfgang Sommergruber; Norbert Kraut; Axel Ullrich; Reinhard Fässler; Rüdiger Klein
Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation.
Nature medicine 2006;12(5):568-73.
2006: Christian Rupp; Helmut Dolznig; Christina Puri; Norbert Schweifer; Wolfgang Sommergruber; Norbert Kraut; Wolfgang J Rettig; Dontscho Kerjaschki; Pilar Garin-Chesa
Laser capture microdissection of epithelial cancers guided by antibodies against fibroblast activation protein and endosialin.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2006;15(1):35-42.
2006: Christian Rupp; Helmut Dolznig; Christina Puri; Wolfgang Sommergruber; Dontscho Kerjaschki; Wolfgang J Rettig; Pilar Garin-Chesa
Mouse endosialin, a C-type lectin-like cell surface receptor: expression during embryonic development and induction in experimental cancer neoangiogenesis.
Cancer immunity 2006;6():10.
2005: Ulrich Koenig; Wolfgang Sommergruber; Saskia Lippens
Aberrant expression of caspase-14 in epithelial tumors.
Biochemical and biophysical research communications 2005;335(2):309-13.
2004: Zunyan Dai; Anthony P Popkie; Wei-Guo Zhu; Cynthia Timmers; Aparna Raval; Sarah H Tannehill-Gregg; Carl D Morrison; Herbert Auer; Robert A Kratzke; Gloria A Niehans; Stefan Amatschek; Wolfgang Sommergruber; Gustavo W Leone; Thomas J Rosol; Gregory A Otterson; Christoph Plass
Bone morphogenetic protein 3B silencing in non-small-cell lung cancer.
Oncogene 2004;23(20):3521-9.
2004: Stefan Amatschek; Ulrich Koenig; Herbert Auer; Peter Steinlein; Margit Pacher; Agnes Gruenfelder; Gerhard Dekan; Sonja Vogl; Ernst Kubista; Karl-Heinz Heider; Christian Stratowa; Martin Schreiber; Wolfgang Sommergruber
Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes.
Cancer research 2004;64(3):844-56.
2003: Alessandra Gradi; Yuri V Svitkin; Wolfgang Sommergruber; Hiroaki Imataka; Shigenobu Morino; Tim Skern; Nahum Sonenberg
Human rhinovirus 2A proteinase cleavage sites in eukaryotic initiation factors (eIF) 4GI and eIF4GII are different.
Journal of virology 2003;77(8):5026-9.
2002: Christoph S Klade; Alexander Michael Dohnal; Walter Fürst; Wolfgang Sommergruber; Karl-Heinz Heider; Helen Gharwan; Manfred Ratschek; Günther R Adolf
Identification and characterization of 9D7, a novel human protein overexpressed in renal cell carcinoma.
International journal of cancer. Journal international du cancer 2002;97(2):217-24.
2001: Marwa Scherl-Mostageer; Wolfgang Sommergruber; Roger Abseher; R Hauptmann; P Ambros; Norbert Schweifer
Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer.
Oncogene 2001;20(32):4402-8.
2000: Joachim Seipelt; Hans-Dieter Liebig; Wolfgang Sommergruber; Christopher Gerner; Ernst Kuechler
2A proteinase of human rhinovirus cleaves cytokeratin 8 in infected HeLa cells.
The Journal of biological chemistry 2000;275(26):20084-9.
1999: Joachim Seipelt; Alba Guarné; E Bergmann; M James; Wolfgang Sommergruber; Ignacio Fita; Tim Skern
The structures of picornaviral proteinases.
Virus research 1999;62(2):159-68.
1997: Wolfgang Sommergruber; Joachim Seipelt; F Fessl; Tim Skern; Hans-Dieter Liebig; G Casari
Mutational analyses support a model for the HRV2 2A proteinase.
Virology 1997;234(2):203-14.
1996: M Luderer-Gmach; Hans-Dieter Liebig; Wolfgang Sommergruber; T Voss; F Fessl; Tim Skern; Ernst Kuechler
Human rhinovirus 2A proteinase mutant and its second-site revertants.
The Biochemical journal 1996;318 ( Pt 1)():213-8.
1995: T Voss; R Meyer; Wolfgang Sommergruber
Spectroscopic characterization of rhinoviral protease 2A: Zn is essential for the structural integrity.
Protein science : a publication of the Protein Society 1995;4(12):2526-31.
1994: Wolfgang Sommergruber; G Casari; F Fessl; Joachim Seipelt; Tim Skern
The 2A proteinase of human rhinovirus is a zinc containing enzyme.
Virology 1994;204(2):815-8.
1994: R Kirchweger; E Ziegler; Barry J Lamphear; D Waters; Hans-Dieter Liebig; Wolfgang Sommergruber; F Sobrino; C Hohenadl; Dieter Blaas; Robert E Rhoads
Foot-and-mouth disease virus leader proteinase: purification of the Lb form and determination of its cleavage site on eIF-4 gamma.
Journal of virology 1994;68(9):5677-84.
1994: Wolfgang Sommergruber; Horst Ahorn; H Klump; Joachim Seipelt; A Zoephel; F Fessl; E Krystek; Dieter Blaas; Ernst Kuechler; Hans-Dieter Liebig
2A proteinases of coxsackie- and rhinovirus cleave peptides derived from eIF-4 gamma via a common recognition motif.
Virology 1994;198(2):741-5.
1993: Fatima Ferreira; Karin Hoffmann-Sommergruber; Heimo Breiteneder; K Pettenburger; Christof Ebner; Wolfgang Sommergruber; R Steiner; Barbara Bohle; W R Sperr; Peter Valent
Purification and characterization of recombinant Bet v I, the major birch pollen allergen. Immunological equivalence to natural Bet v I.
The Journal of biological chemistry 1993;268(26):19574-80.
1993: Hans-Dieter Liebig; E Ziegler; Riqiang Yan; Klaus Hartmuth; H Klump; H Kowalski; Dieter Blaas; Wolfgang Sommergruber; L Frasel; Barry J Lamphear
Purification of two picornaviral 2A proteinases: interaction with eIF-4 gamma and influence on in vitro translation.
Biochemistry 1993;32(29):7581-8.
1992: Wolfgang Sommergruber; Horst Ahorn; A Zöphel; I Maurer-Fogy; F Fessl; G Schnorrenberg; Hans-Dieter Liebig; Dieter Blaas; Ernst Kuechler; Tim Skern
Cleavage specificity on synthetic peptide substrates of human rhinovirus 2 proteinase 2A.
The Journal of biological chemistry 1992;267(31):22639-44.
1992: M Luderer; Hans-Dieter Liebig; Wolfgang Sommergruber; Dieter Blaas; Ernst Kuechler; Tim Skern
Using proteinase trapping to detect revertants of inactive rhinoviral 2A proteinase mutants.
Biological chemistry Hoppe-Seyler 1992;373(7):523-8.
1991: Hans-Dieter Liebig; Tim Skern; M Luderer; Wolfgang Sommergruber; Dieter Blaas; Ernst Kuechler
Proteinase trapping: screening for viral proteinase mutants by alpha complementation.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(14):5979-83.
1991: Günther R Adolf; B Frühbeis; R Hauptmann; I Kalsner; I Maurer-Fogy; E Ostermann; E Patzelt; R Schwendenwein; Wolfgang Sommergruber; A Zöphel
Human interferon omega 1: isolation of the gene, expression in Chinese hamster ovary cells and characterization of the recombinant protein.
Biochimica et biophysica acta 1991;1089(2):167-74.
1991: Tim Skern; Wolfgang Sommergruber; H Auer; P Volkmann; M Zorn; Hans-Dieter Liebig; F Fessl; Dieter Blaas; Ernst Kuechler
Substrate requirements of a human rhinoviral 2A proteinase.
Virology 1991;181(1):46-54.
1990: Tim Skern; M Zorn; D Blaas; E Kuechler; Wolfgang Sommergruber
Protease or protease inhibitor?
Nature 1990;344(6261):26.
1989: N Uchibayashi; Hitoshi Kikutani; E L Barsumian; R Hauptmann; F J Schneider; R Schwendenwein; Wolfgang Sommergruber; W Spevak; I Maurer-Fogy; Masaki Suemura
Recombinant soluble Fc epsilon receptor II (Fc epsilon RII/CD23) has IgE binding activity but no B cell growth promoting activity.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(11):3901-8.
1989: Wolfgang Sommergruber; M Zorn; Dieter Blaas; F Fessl; P Volkmann; I Maurer-Fogy; P Pallai; V Merluzzi; M Matteo; Tim Skern
Polypeptide 2A of human rhinovirus type 2: identification as a protease and characterization by mutational analysis.
Virology 1989;169(1):68-77.
1989: M Duechler; Tim Skern; Dieter Blaas; B Berger; Wolfgang Sommergruber; Ernst Kuechler
Human rhinovirus serotype 2: in vitro synthesis of an infectious RNA.
Virology 1989;168(1):159-61.
1987: M Duechler; Tim Skern; Wolfgang Sommergruber; C Neubauer; P Gruendler; I Fogy; Dieter Blaas; Ernst Kuechler
Evolutionary relationships within the human rhinovirus genus: comparison of serotypes 89, 2, and 14.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(9):2605-9.
1987: Tim Skern; C Neubauer; L Frasel; P Gründler; Wolfgang Sommergruber; M Zorn; Ernst Kuechler; Dieter Blaas
A neutralizing epitope on human rhinovirus type 2 includes amino acid residues between 153 and 164 of virus capsid protein VP2.
The Journal of general virology 1987;68 ( Pt 2)():315-23.
1987: Tim Skern; M Duechler; Wolfgang Sommergruber; Dieter Blaas; Ernst Kuechler
The molecular biology of human rhinoviruses.
Biochemical Society symposium 1987;53():63-73.
1985: Tim Skern; Wolfgang Sommergruber; Dieter Blaas; P Gruendler; F Fraundorfer; C Pieler; I Fogy; Ernst Kuechler
Human rhinovirus 2: complete nucleotide sequence and proteolytic processing signals in the capsid protein region.
Nucleic acids research 1985;13(6):2111-26.
1984: Tim Skern; Wolfgang Sommergruber; Dieter Blaas; C Pieler; Ernst Kuechler
Relationship of human rhinovirus strain 2 and poliovirus as indicated by comparison of the polymerase gene regions.
Virology 1984;136(1):125-32.