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Malle Soom

Research Profile

Physiology

Chemicals & Drugs

Concepts & Ideas

Living Beings

Procedures

Patch-Clamp Techniques

Anatomy

Disorders

Andersen Syndrome

Genes & Molecular Sequences

Amino Acid Sequences

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Publications

TOP 3
Guido Gessner; Yong-Mei Cui; Toshinori Hoshi; Tomohiko Ohwada; Yuko Otani; Malle Soom; Stefan H Heinemann
Molecular mechanism of pharmacological activation of BK channels.
Kerstin Huenniger; Andreas Krämer; Malle Soom; Iree Chang; Matthias Köhler; Reinhard Depping; Ralph H Kehlenbach; Christoph Kaether
Notch1 signaling is mediated by importins alpha 3, 4, and 7.
Ralf P Friedrich; Katharina Tepper; Raik Rönicke; Malle Soom; Martin Westermann; Klaus Reymann; Christoph Kaether; Marcus Fändrich
Mechanism of amyloid plaque formation suggests an intracellular basis of Abeta pathogenicity.

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All Publications

2012: Guido Gessner; Yong-Mei Cui; Toshinori Hoshi; Tomohiko Ohwada; Yuko Otani; Malle Soom; Stefan H Heinemann
Molecular mechanism of pharmacological activation of BK channels.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(9):3552-7.
2010: Kerstin Huenniger; Andreas Krämer; Malle Soom; Iree Chang; Matthias Köhler; Reinhard Depping; Ralph H Kehlenbach; Christoph Kaether
Notch1 signaling is mediated by importins alpha 3, 4, and 7.
Cellular and molecular life sciences : CMLS 2010;67(18):3187-96.
2010: Ralf P Friedrich; Katharina Tepper; Raik Rönicke; Malle Soom; Martin Westermann; Klaus Reymann; Christoph Kaether; Marcus Fändrich
Mechanism of amyloid plaque formation suggests an intracellular basis of Abeta pathogenicity.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(5):1942-7.
2008: Niels Decher; Teresa Gonzalez; Anne Kathrin Streit; Frank B Sachse; Vijay Renigunta; Malle Soom; Stefan H Heinemann; Jürgen Daut; Michael C Sanguinetti
Structural determinants of Kvbeta1.3-induced channel inactivation: a hairpin modulated by PIP2.
The EMBO journal 2008;27(23):3164-74.
2008: Malle Soom; Guido Gessner; Heike Heuer; Toshinori Hoshi; Stefan H Heinemann
A mutually exclusive alternative exon of slo1 codes for a neuronal BK channel with altered function.
Channels (Austin, Tex.) 2008;2(4):278-82.
2007: Niels Decher; Vijay Renigunta; Marylou Zuzarte; Malle Soom; Stefan H Heinemann; Katherine W Timothy; Mark T Keating; Jürgen Daut; Michael C Sanguinetti; Igor Splawski
Impaired interaction between the slide helix and the C-terminus of Kir2.1: a novel mechanism of Andersen syndrome.
Cardiovascular research 2007;75(4):748-57.
2005: Guido Gessner; Kristina Schönherr; Malle Soom; Alfred Hansel; M Asim; Aria Baniahmad; C Derst; Toshinori Hoshi; Stefan H Heinemann
BKCa channels activating at resting potential without calcium in LNCaP prostate cancer cells.
The Journal of membrane biology 2005;208(3):229-40.
2005: Markus Rapedius; Malle Soom; Ekaterina Shumilina; Dirk Schulze; Roland Schönherr; Cornelia Kirsch; Florian Lang; Stephen J Tucker; Thomas Baukrowitz
Long chain CoA esters as competitive antagonists of phosphatidylinositol 4,5-bisphosphate activation in Kir channels.
The Journal of biological chemistry 2005;280(35):30760-7.
2005: Beatrice L Pool-Zobel; Veeriah Selvaraju; Julia Sauer; Tanja Kautenburger; Jeannette Kiefer; Konrad Klaus Richter; Malle Soom; Stefan Wölfl
Butyrate may enhance toxicological defence in primary, adenoma and tumor human colon cells by favourably modulating expression of glutathione S-transferases genes, an approach in nutrigenomics.
Carcinogenesis 2005;26(6):1064-76.
2004: Dominik Oliver; Cheng-Chang Lien; Malle Soom; Thomas Baukrowitz; Peter Jonas; Bernd Fakler
Functional conversion between A-type and delayed rectifier K+ channels by membrane lipids.
Science (New York, N.Y.) 2004;304(5668):265-70.
2003: Dirk Schulze; Tobias Krauter; Hariolf Fritzenschaft; Malle Soom; Thomas Baukrowitz
Phosphatidylinositol 4,5-bisphosphate (PIP2) modulation of ATP and pH sensitivity in Kir channels. A tale of an active and a silent PIP2 site in the N terminus.
The Journal of biological chemistry 2003;278(12):10500-5.
2001: Malle Soom; Roland Schönherr; Y Kubo; Cornelia Kirsch; Reinhard Klinger; Stefan H Heinemann
Multiple PIP2 binding sites in Kir2.1 inwardly rectifying potassium channels.
FEBS letters 2001;490(1-2):49-53.