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Ursel Soomets

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Hedi Harzia; Ivi Jõudu; Tanel Kaart; Olav Kärt; Marko Kass; Kalle Kilk; Tiia Ariko; David Arney; Ursel Soomets; Mai Ots
Crude glycerol as glycogenic precursor in feed; effects on milk coagulation properties and metabolic profiles of dairy cows.
Sulev Kõks; Rupert W Overall; Cathy Fernandes; Mithu Guha; Marilin Ivask; Ursel Soomets; Eero Vasar; Leo C Schalkwyk
Silencing of the WFS1 gene in HEK cells induces pathways related to neurodegeneration and mitochondrial damage.
Margit Lill; Irja Lutsar; Leonard C Schalkwyk; Ursel Soomets; Cathy Fernandes; Sulev Kõks; Pille Taba
Peripheral blood RNA gene expression profiling in patients with bacterial meningitis.

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All Publications

2013: Hedi Harzia; Ivi Jõudu; Tanel Kaart; Olav Kärt; Marko Kass; Kalle Kilk; Tiia Ariko; David Arney; Ursel Soomets; Mai Ots
Crude glycerol as glycogenic precursor in feed; effects on milk coagulation properties and metabolic profiles of dairy cows.
The Journal of dairy research 2013;80(2):190-6.
2013: Sulev Kõks; Rupert W Overall; Cathy Fernandes; Mithu Guha; Marilin Ivask; Ursel Soomets; Eero Vasar; Leo C Schalkwyk
Silencing of the WFS1 gene in HEK cells induces pathways related to neurodegeneration and mitochondrial damage.
Physiological genomics 2013;45(5):182-90.
2013: Margit Lill; Irja Lutsar; Leonard C Schalkwyk; Ursel Soomets; Cathy Fernandes; Sulev Kõks; Pille Taba
Peripheral blood RNA gene expression profiling in patients with bacterial meningitis.
Frontiers in neuroscience 2013;7():33.
2013: Kristiina Laanemets; Stephen Lee; Ove Lindgren; Ebe Merilo; Noriyuki Nishimura; Julian I Schroeder; Ursel Soomets; Yong-Fei Wang; Juyou Wu; Mikael Brosche; Daniel Caddell; Jaakko Kangasjärvi; Kalle Kilk; Hannes Kollist
Mutations in the SLAC1 anion channel slow stomatal opening and severely reduce K+ uptake channel activity via enhanced cytosolic [Ca2+] and increased Ca2+ sensitivity of K+ uptake channels.
The New phytologist 2013;197(1):88-98.
2012: Aigi Ilves; K Ling; Mai Ots; Ursel Soomets; H Harzia; Kalle Kilk
Alterations in milk and blood metabolomes during the first months of lactation in dairy cows.
Journal of dairy science 2012;95(10):5788-97.
2012: H Harzia; M Henno; I Jõudu; O Kärt; Kalle Kilk; Ursel Soomets
Comparison of the metabolic profiles of noncoagulating and coagulating bovine milk.
Journal of dairy science 2012;95(2):533-40.
2012: K Joost; K Kall; Kalle Kilk; R K Olsen; Katrin Ounap; Ursel Soomets; M-L Uudelepp; Riina Zordania; Tiina Kahre
Prevalence of Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency in Estonia.
JIMD reports 2012;2():79-85.
2012: Ceslava Kairane; Kalle Kilk; Riina Mahlapuu; Kersti Ehrlich; Mihkel Zilmer; Ursel Soomets
Diverse Effects of Glutathione and UPF Peptides on Antioxidant Defense System in Human Erythroleukemia Cells K562.
International journal of peptides 2012;2012():124163.
2011: Anton Terasmaa; Kersti Ehrlich; Mats Hansen; Sulev Kõks; Vallo Matto; Anne Must; Julia Oflijan; Marite Punapart; Ursel Soomets; Eero Vasar
Wfs1 mutation makes mice sensitive to insulin-like effect of acute valproic acid and resistant to streptozocin.
Journal of physiology and biochemistry 2011;67(3):381-90.
2011: Katrin Sikk; Ursel Soomets; Sten-Magnus Aquilonius; Cathy Fernandes; Sulev Haldre; Sulev Kõks; Leonard C Schalkwyk; Pille Taba
Peripheral blood RNA expression profiling in illicit methcathinone users reveals effect on immune system.
Frontiers in genetics 2011;2():42.
2010: Peeter Hõrak; Elin Sild; Ursel Soomets; Tuul Sepp; Kalle Kilk
Oxidative stress and information content of black and yellow plumage coloration: an experiment with greenfinches.
The Journal of experimental biology 2010;213(Pt 13):2225-33.
2010: S Kõks; A Velthut; A Sarapik; Signe Altmäe; E Reinmaa; L C Schalkwyk; C Fernandes; H V Lad; Ursel Soomets; U Jaakma; Andres Salumets
The differential transcriptome and ontology profiles of floating and cumulus granulosa cells in stimulated human antral follicles.
Molecular human reproduction 2010;16(4):229-40.
2009: Kalle Kilk; Riina Mahlapuu; Ursel Soomets; Ulo Langel
Analysis of in vitro toxicity of five cell-penetrating peptides by metabolic profiling.
Toxicology 2009;265(3):87-95.
2009: Säde Viirlaid; Riina Mahlapuu; Kalle Kilk; Aleksei Kuznetsov; Ursel Soomets; Jaak Järv
Mechanism and stoichiometry of 2,2-diphenyl-1-picrylhydrazyl radical scavenging by glutathione and its novel alpha-glutamyl derivative.
Bioorganic chemistry 2009;37(4):126-32.
2009: Kersti Ehrlich; Katrin Ida; Riina Mahlapuu; Ceslava Kairane; Ingrid Oit; Mihkel Zilmer; Ursel Soomets
Characterization of UPF peptides, members of the glutathione analogues library, on the basis of their effects on oxidative stress-related enzymes.
Free radical research 2009;43(6):572-80.
2009: S Kõks; Ursel Soomets; J L Paya-Cano; C Fernandes; Hendrik Luuk; Mario Plaas; Anton Terasmaa; Vallo Tillmann; K Noormets; Eero Vasar; L C Schalkwyk
Wfs1 gene deletion causes growth retardation in mice and interferes with the growth hormone pathway.
Physiological genomics 2009;37(3):249-59.
2009: Anna Meszka-Jordan; Riina Mahlapuu; Ursel Soomets; Gary P Carlson
Oxidative stress due to (R)-styrene oxide exposure and the role of antioxidants in non-Swiss albino (NSA) mice.
Journal of toxicology and environmental health. Part A 2009;72(10):642-50.
2008: Jaak Kals; Joel Starkopf; Mihkel Zilmer; Tõnis Pruler; Kristel Pulges; Monika Hallaste; Mart Kals; Andres Pulges; Ursel Soomets
Antioxidant UPF1 attenuates myocardial stunning in isolated rat hearts.
International journal of cardiology 2008;125(1):133-5.
2007: Külli Kingo; Eerik Aunin; Mati Karelson; Mari-Anne Philips; Ranno Rätsep; Helgi Silm; Eero Vasar; Ursel Soomets; Sulev Kõks
Gene expression analysis of melanocortin system in vitiligo.
Journal of dermatological science 2007;48(2):113-22.
2007: Kersti Ehrlich; Säde Viirlaid; Riina Mahlapuu; Külliki Saar; Tiiu Kullisaar; Mihkel Zilmer; Ulo Langel; Ursel Soomets
Design, synthesis and properties of novel powerful antioxidants, glutathione analogues.
Free radical research 2007;41(7):779-87.
2006: Riina Mahlapuu; Merike Vaher; Kersti Ehrlich; Mihkel Kaljurand; Ursel Soomets
Comparison of the stability of glutathione and related synthetic tetrapeptides by HPLC and capillary electrophoresis.
Journal of peptide science : an official publication of the European Peptide Society 2006;12(12):796-9.
2006: Merike Vaher; Säde Viirlaid; Kersti Ehrlich; Riina Mahlapuu; Jüri Jarvet; Ursel Soomets; Mihkel Kaljurand
Characterization of the antioxidative activity of novel nontoxic neuropeptides by using capillary electrophoresis.
Electrophoresis 2006;27(13):2582-9.
2005: Ursel Soomets; Mihkel Zilmer; Ulo Langel
Manual solid-phase synthesis of glutathione analogs: a laboratory-based short course.
Methods in molecular biology (Clifton, N.J.) 2005;298():241-57.
2004: P Põder; Mihkel Zilmer; Joel Starkopf; Jaak Kals; A Talonpoika; Andres Pulges; Ulo Langel; Tiiu Kullisaar; Säde Viirlaid; Riina Mahlapuu; A Zarkovski; Andres Arend; Ursel Soomets
An antioxidant tetrapeptide UPF1 in rats has a neuroprotective effect in transient global brain ischemia.
Neuroscience letters 2004;370(1):45-50.
2004: Kalle Kilk; Anna Elmquist; Külliki Saar; Margus Pooga; Tiit Land; Tamas Bartfai; Ursel Soomets; Ulo Langel
Targeting of antisense PNA oligomers to human galanin receptor type 1 mRNA.
Neuropeptides 2004;38(5):316-24.
2004: L Fisher; Ursel Soomets; Veronica Cortés Toro; Lucy Chilton; Yang Jiang; Ulo Langel; Kerstin Iverfeldt
Cellular delivery of a double-stranded oligonucleotide NFkappaB decoy by hybridization to complementary PNA linked to a cell-penetrating peptide.
Gene therapy 2004;11(16):1264-72.
2003: Riina Mahlapuu; Kaido Viht; Lajos Balaspiri; Nenad Bogdanovic; Külliki Saar; Ursel Soomets; Tiit Land; Mihkel Zilmer; Ello Karelson; Ulo Langel
Amyloid precursor protein carboxy-terminal fragments modulate G-proteins and adenylate cyclase activity in Alzheimer's disease brain.
Brain research. Molecular brain research 2003;117(1):73-82.
2003: Linda Adlerz; Ursel Soomets; Linda Holmlund; Säde Viirlaid; Ulo Langel; Kerstin Iverfeldt
Down-regulation of amyloid precursor protein by peptide nucleic acid oligomer in cultured rat primary neurons and astrocytes.
Neuroscience letters 2003;336(1):55-9.
2002: Ello Karelson; Riina Mahlapuu; Mihkel Zilmer; Ursel Soomets; Nenad Bogdanovic; Ulo Langel
Possible signaling by glutathione and its novel analogue through potent stimulation of fontocortical G proteins in normal aging and in Alzheimer's disease.
Annals of the New York Academy of Sciences 2002;973():537-40.
2002: Külliki Saar; Andrey Mazarati; Riina Mahlapuu; Gerd Hallnemo; Ursel Soomets; Kalle Kilk; Sven Hellberg; Margus Pooga; Bo-Ragnar Tolf; Tiejun S Shi; Tomas Hökfelt; Claude Wasterlain; Tamas Bartfai; Ulo Langel
Anticonvulsant activity of a nonpeptide galanin receptor agonist.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):7136-41.
2002: Margus Pooga; Ursel Soomets; Tamas Bartfai; Ulo Langel
Synthesis of cell-penetrating peptide-PNA constructs.
Methods in molecular biology (Clifton, N.J.) 2002;208():225-36.
2002: Michelle Farquhar; Ursel Soomets; Ruth L Bates; Ashley Martin; Ulo Langel; John Howl
Novel mastoparan analogs induce differential secretion from mast cells.
Chemistry & biology 2002;9(1):63-70.
2001: K Rezaei; Isabella Shi Xu; Wei-Ping Wu; Tie-Jun Sten Shi; Ursel Soomets; Tiit Land; Xiao-Jun Xu; Zsuzsanna Wiesenfeld-Hallin; Tomas Hökfelt; Tamas Bartfai; Ulo Langel
Intrathecal administration of PNA targeting galanin receptor reduces galanin-mediated inhibitory effect in the rat spinal cord.
Neuroreport 2001;12(2):317-20.
2000: Maria Lindgren; X Gallet; Ursel Soomets; Mattias Hällbrink; Ebba Brakenhielm; Margus Pooga; Robert Brasseur; Ulo Langel
Translocation properties of novel cell penetrating transportan and penetratin analogues.
Bioconjugate chemistry 2000;11(5):619-26.
2000: Ursel Soomets; Maria Lindgren; X Gallet; Mattias Hällbrink; Anna Elmquist; Lajos Balaspiri; Matjaz Zorko; Margus Pooga; Robert Brasseur; Ulo Langel
Deletion analogues of transportan.
Biochimica et biophysica acta 2000;1467(1):165-76.
2000: K Rezaei; Külliki Saar; Ursel Soomets; Andres Valkna; J Näsman; Matjaz Zorko; Karl E O Akerman; T Schroeder; Tamas Bartfai; Ulo Langel
Role of third intracellular loop of galanin receptor type 1 in signal transduction.
Neuropeptides 2000;34(1):25-31.
1999: Ursel Soomets; Riina Mahlapuu; Roya Tehranian; Jüri Jarvet; Ello Karelson; Mihkel Zilmer; Kerstin Iverfeldt; Matjaz Zorko; Astrid Gräslund; Ulo Langel
Regulation of GTPase and adenylate cyclase activity by amyloid beta-peptide and its fragments in rat brain tissue.
Brain research 1999;850(1-2):179-88.
1999: Ursel Soomets; Mattias Hällbrink; Ulo Langel
Antisense properties of peptide nucleic acids.
Frontiers in bioscience : a journal and virtual library 1999;4():D782-6.
1999: Mattias Hällbrink; Külliki Saar; Claes-Göran Ostenson; Ursel Soomets; Suad Efendic; John Howl; Mark Wheatley; Matjaz Zorko; Ulo Langel
Effects of vasopressin-mastoparan chimeric peptides on insulin release and G-protein activity.
Regulatory peptides 1999;82(1-3):45-51.
1998: Andrey Mazarati; Hantao Liu; Ursel Soomets; Raman Sankar; Don Shin; Hiroshi Katsumori; Ulo Langel; Claude Wasterlain
Galanin modulation of seizures and seizure modulation of hippocampal galanin in animal models of status epilepticus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(23):10070-7.
1998: Margus Pooga; Ursel Soomets; Mattias Hällbrink; Andres Valkna; Külliki Saar; K Rezaei; U Kahl; Jing-Xia Hao; Xiao-Jun Xu; Zsuzsanna Wiesenfeld-Hallin; Tomas Hökfelt; Tamas Bartfai; Ulo Langel
Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo.
Nature biotechnology 1998;16(9):857-61.
1998: CL Longland; M Mezna; Ulo Langel; Mattias Hällbrink; Ursel Soomets; Mark Wheatley; Francesco Michelangeli; John Howl
Biochemical mechanisms of calcium mobilisation induced by mastoparan and chimeric hormone-mastoparan constructs.
Cell calcium 1998;24(1):27-34.
1997: Külliki Saar; Andres Valkna; Ursel Soomets; K Rezaei; Matjaz Zorko; Mihkel Zilmer; Ulo Langel
Role of the third cytoplasmic loop in signal transduction by galanin receptors.
Biochemical Society transactions 1997;25(3):1036-40.
1997: Ursel Soomets; Ceslava Kairane; Mihkel Zilmer; U Langel
Attempt to solubilize Na+/K+-exchanging ATPase with amphiphilic peptide PD1.
Acta chemica Scandinavica (Copenhagen, Denmark : 1989) 1997;51(3 Suppl):403-6.