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Sieghart Sopper

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Thorsten Nolting; Sieghart Sopper; Olaf Stüve; Gabriele Arendt; Hans-Peter Hartung; Ingo-W Husstedt; Eleni Koutsilieri; Antje Lindecke; Matthias Maschke
Cytokine levels in CSF and neuropsychological performance in HIV patients.
Maximilian Boesch; Daniel Reimer; Holger Rumpold; Sieghart Sopper; Alain G Zeimet; Dominik Wolf
DyeCycle Violet used for side population detection is a substrate of P-glycoprotein.
Anke Schultz; Sieghart Sopper; Andreas Meyerhans; Ulrike Sauermann; Rodolphe Suspène
Stable multi-infection of splenocytes during SIV infection--the basis for continuous recombination.

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2012: Thorsten Nolting; Sieghart Sopper; Olaf Stüve; Gabriele Arendt; Hans-Peter Hartung; Ingo-W Husstedt; Eleni Koutsilieri; Antje Lindecke; Matthias Maschke
Cytokine levels in CSF and neuropsychological performance in HIV patients.
Journal of neurovirology 2012;18(3):157-61.
2012: Maximilian Boesch; Daniel Reimer; Holger Rumpold; Sieghart Sopper; Alain G Zeimet; Dominik Wolf
DyeCycle Violet used for side population detection is a substrate of P-glycoprotein.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2012;81(6):517-22.
2012: Anke Schultz; Sieghart Sopper; Andreas Meyerhans; Ulrike Sauermann; Rodolphe Suspène
Stable multi-infection of splenocytes during SIV infection--the basis for continuous recombination.
Retrovirology 2012;9():31.
2011: Kathrin Eller; Alexander Kirsch; Wolfgang Patsch; Alexander R Rosenkranz; Sieghart Sopper; Ursula Stanzl; Andrea Tagwerker; Anna M Wolf; Dominik Wolf; Philipp Eller
Potential role of regulatory T cells in reversing obesity-linked insulin resistance and diabetic nephropathy.
Diabetes 2011;60(11):2954-62.
2011: Tanja Bischoff; Christiane Stahl-Hennig; Kerstin Mätz-Rensing; Eleni Koutsilieri; Sieghart Sopper
Definition of leukocyte subsets in primate central nervous system by polychromatic flow cytometry.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2011;79(6):436-45.
2011: Tina Schultheiss; Nicole Stolte-Leeb; Sieghart Sopper; Christiane Stahl-Hennig
Flow cytometric characterization of the lymphocyte composition in a variety of mucosal tissues in healthy rhesus macaques.
Journal of medical primatology 2011;40(1):41-51.
2011: Bianka Mussil; Ulrike Sauermann; Dirk Motzkus; Christiane Stahl-Hennig; Sieghart Sopper
Increased APOBEC3G and APOBEC3F expression is associated with low viral load and prolonged survival in simian immunodeficiency virus infected rhesus monkeys.
Retrovirology 2011;8():77.
2010: C Leinert; Christiane Stahl-Hennig; A Ecker; T Schneider; Dietmar Fuchs; Ulrike Sauermann; Sieghart Sopper
Microbial translocation in simian immunodeficiency virus (SIV)-infected rhesus monkeys (Macaca mulatta).
Journal of medical primatology 2010;39(4):243-51.
2010: Carsten Scheller; G Arendt; T Nolting; C Antke; Sieghart Sopper; M Maschke; M Obermann; A Angerer; I W Husstedt; F Meisner; E Neuen-Jacob; H W Müller; P Carey; Volker ter Meulen; Peter Riederer; Eleni Koutsilieri
Increased dopaminergic neurotransmission in therapy-naïve asymptomatic HIV patients is not associated with adaptive changes at the dopaminergic synapses.
Journal of neural transmission (Vienna, Austria : 1996) 2010;117(6):699-705.
2009: Washingtone Ochieng; Ulrike Sauermann; Reiner Schulte; You-Suk Suh; Kwang Soon Kim; Young C Sung; Gerhard Hunsmann; Christiane Stahl-Hennig; Sieghart Sopper
Susceptibility to Simian immunodeficiency virus ex vivo predicts outcome of a prime-boost vaccine after SIVmac239 challenge.
Journal of acquired immune deficiency syndromes (1999) 2009;52(2):162-9.
2009: Thorsten Nolting; Antje Lindecke; Eleni Koutsilieri; Matthias Maschke; Ingo-W Husstedt; Sieghart Sopper; Olaf Stüve; Hans-Peter Hartung; Gabriele Arendt
Measurement of soluble inflammatory mediators in cerebrospinal fluid of human immunodeficiency virus-positive patients at distinct stages of infection by solid-phase protein array.
Journal of neurovirology 2009;15(5-6):390-400.
2009: Reiner Schulte; You-Suk Suh; Ulrike Sauermann; Washingtone Ochieng; Sieghart Sopper; Kwang Soon Kim; So-Shin Ahn; Ki S Park; Nicole Stolte-Leeb; Gerhard Hunsmann; Young Chul Sung; Christiane Stahl-Hennig
Mucosal prior to systemic application of recombinant adenovirus boosting is more immunogenic than systemic application twice but confers similar protection against SIV-challenge in DNA vaccine-primed macaques.
Virology 2009;383(2):300-9.
2008: Falko Meisner; Carsten Scheller; Susanne Kneitz; Sieghart Sopper; Eva Neuen-Jacob; Peter Riederer; Volker ter Meulen; Eleni Koutsilieri
Memantine upregulates BDNF and prevents dopamine deficits in SIV-infected macaques: a novel pharmacological action of memantine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2008;33(9):2228-36.
2008: Maria Cecilia G Marcondes; Sieghart Sopper; Ulrike Sauermann; Tricia H Burdo; Debbie D Watry; Michelle A Zandonatti; Howard S Fox
CD4 deficits and disease course acceleration can be driven by a collapse of the CD8 response in rhesus macaques infected with simian immunodeficiency virus.
AIDS (London, England) 2008;22(12):1441-52.
2008: Falko Meisner; Eva Neuen-Jacob; Sieghart Sopper; Michaela Schmidt; Serge Schlammes; Carsten Scheller; Daniel Vosswinkel; Volker ter Meulen; Peter Riederer; Eleni Koutsilieri
Disruption of excitatory amino acid transporters in brains of SIV-infected rhesus macaques is associated with microglia activation.
Journal of neurochemistry 2008;104(1):202-9.
2007: Gabriele Arendt; Thorsten Nolting; Christian Frisch; Ingo-W Husstedt; Nora Gregor; Eleni Koutsilieri; Matthias Maschke; Alexander Angerer; Mark Obermann; Eva Neuen-Jacob; Ortwin Adams; Sabine Loeffert; Peter Riederer; Volker ter Meulen; Sieghart Sopper
Intrathecal viral replication and cerebral deficits in different stages of human immunodeficiency virus disease.
Journal of neurovirology 2007;13(3):225-32.
2007: Maria Cecilia G Marcondes; Tricia H Burdo; Sieghart Sopper; Salvador Huitron-Resendiz; Caroline Lanigan; Debbie D Watry; Claudia Flynn; Michelle A Zandonatti; Howard S Fox
Enrichment and persistence of virus-specific CTL in the brain of simian immunodeficiency virus-infected monkeys is associated with a unique cytokine environment.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(9):5812-9.
2007: Susanne Kneitz; F Meisner; Sieghart Sopper; F Kaiser; Edna Grünblatt; Carsten Scheller; Peter Riederer; Volker ter Meulen; Eleni Koutsilieri
Biostatistical analysis of gene microarrays reveals diverse expression clusters between macaque subspecies in brain SIV infection.
Journal of neural transmission. Supplementum 2007;(72):317-22.
2006: Carsten Scheller; Johanna Knöferle; Anett Ullrich; Johannes Prottengeier; Tomas Racek; Sieghart Sopper; Christian Jassoy; Axel Rethwilm; Eleni Koutsilieri
Caspase inhibition in apoptotic T cells triggers necrotic cell death depending on the cell type and the proapoptotic stimulus.
Journal of cellular biochemistry 2006;97(6):1350-61.
2005: Carsten Scheller; Sieghart Sopper; Meta Jenuwein; Eva Neuen-Jacob; Thomas Tatschner; Edna Grünblatt; Volker ter Meulen; Peter Riederer; Eleni Koutsilieri
Early impairment in dopaminergic neurotransmission in brains of SIV-infected rhesus monkeys due to microglia activation.
Journal of neurochemistry 2005;95(2):377-87.
2005: Cornelia Speth; Manfred P Dierich; Sieghart Sopper
HIV-infection of the central nervous system: the tightrope walk of innate immunity.
Molecular immunology 2005;42(2):213-28.
2004: M Jenuwein; Carsten Scheller; Eva Neuen-Jacob; Sieghart Sopper; Thomas Tatschner; Volker ter Meulen; Peter Riederer; Eleni Koutsilieri
Dopamine deficits and regulation of the cAMP second messenger system in brains of simian immunodeficiency virus-infected rhesus monkeys.
Journal of neurovirology 2004;10(3):163-70.
2004: Stefanie Czub; Markus Czub; Eleni Koutsilieri; Sieghart Sopper; Francios VILLINGER; Justus G Müller; Christiane Stahl-Hennig; Peter Riederer; Volker ter Meulen; G Gosztonyi
Modulation of simian immunodeficiency virus neuropathology by dopaminergic drugs.
Acta neuropathologica 2004;107(3):216-26.
2003: Carsten Scheller; Sieghart Sopper; Eleni Koutsilieri; Stephan Ludwig; Volker ter Meulen; Christian Jassoy
Caspase inhibitors as a supplement in immune activation therapies to achieve eradication of HIV in its latent reservoirs.
Annals of the New York Academy of Sciences 2003;1010():209-12.
2003: Sieghart Sopper; Dagmar Nierwetberg; Astrid Halbach; Ursula Sauer; Carsten Scheller; Christiane Stahl-Hennig; Kerstin Mätz-Rensing; Frank Schäfer; Thomas Schneider; Volker ter Meulen; Justus G Müller
Impact of simian immunodeficiency virus (SIV) infection on lymphocyte numbers and T-cell turnover in different organs of rhesus monkeys.
Blood 2003;101(4):1213-9.
2003: Christiane Stahl-Hennig; Björn R Gundlach; Ulf Dittmer; Peter Ten Haaft; Jonathan Luke Heeney; Weiping Zou; Dominique Emilie; Sieghart Sopper; Klaus Uberla
Replication, immunogenicity, and protective properties of live-attenuated simian immunodeficiency viruses expressing interleukin-4 or interferon-gamma.
Virology 2003;305(2):473-85.
2002: Eleni Koutsilieri; Carsten Scheller; Sieghart Sopper; Volker ter Meulen; Peter Riederer
Psychiatric complications in human immunodeficiency virus infection.
Journal of neurovirology 2002;8 Suppl 2():129-33.
2002: Carsten Scheller; Sieghart Sopper; Christina Ehrhardt; Egbert Flory; Peifeng Chen; Eleni Koutsilieri; Stephan Ludwig; Volker ter Meulen; Christian Jassoy
Caspase inhibitors induce a switch from apoptotic to proinflammatory signaling in CD95-stimulated T lymphocytes.
European journal of immunology 2002;32(9):2471-80.
2002: Carsten Scheller; Sieghart Sopper; Peifeng Chen; Egbert Flory; Eleni Koutsilieri; Tomas Racek; Stephan Ludwig; Volker ter Meulen; Christian Jassoy
Caspase inhibition activates HIV in latently infected cells. Role of tumor necrosis factor receptor 1 and CD95.
The Journal of biological chemistry 2002;277(18):15459-64.
2002: Eleni Koutsilieri; Sieghart Sopper; Carsten Scheller; Volker ter Meulen; Peter Riederer
Parkinsonism in HIV dementia.
Journal of neural transmission (Vienna, Austria : 1996) 2002;109(5-6):767-75.
2002: Sieghart Sopper; Eleni Koutsilieri; Carsten Scheller; Stefanie Czub; Peter Riederer; Volker ter Meulen
Macaque animal model for HIV-induced neurological disease.
Journal of neural transmission (Vienna, Austria : 1996) 2002;109(5-6):747-66.
2002: Eleni Koutsilieri; Carsten Scheller; Sieghart Sopper; Volker ter Meulen; Peter Riederer
The pathogenesis of HIV-induced dementia.
Mechanisms of ageing and development 2002;123(8):1047-53.
2002: Eleni Koutsilieri; Sieghart Sopper; Carsten Scheller; Volker ter Meulen; Peter Riederer
Involvement of dopamine in the progression of AIDS Dementia Complex.
Journal of neural transmission (Vienna, Austria : 1996) 2002;109(3):399-410.
2001: TA Fischer; Alois Palmetshofer; Stepan Gambaryan; Elke Butt; Christian Jassoy; Ulrich Walter; Sieghart Sopper; Suzanne M Lohmann
Activation of cGMP-dependent protein kinase Ibeta inhibits interleukin 2 release and proliferation of T cell receptor-stimulated human peripheral T cells.
The Journal of biological chemistry 2001;276(8):5967-74.
2001: Stefanie Czub; Eleni Koutsilieri; Sieghart Sopper; Markus Czub; Christiane Stahl-Hennig; Justus G Müller; V Pedersen; W Gsell; Jonathan Luke Heeney; Manfred Gerlach; G Gosztonyi; Peter Riederer; Volker ter Meulen
Enhancement of central nervous system pathology in early simian immunodeficiency virus infection by dopaminergic drugs.
Acta neuropathologica 2001;101(2):85-91.
2001: Eleni Koutsilieri; Carsten Scheller; Sieghart Sopper; Mario E Götz; Manfred Gerlach; Volker ter Meulen; Peter Riederer
Selegiline completely restores choline acetyltransferase activity deficits in simian immunodeficiency infection.
European journal of pharmacology 2001;411(1-2):R1-R2.
2000: Ulrike Sauermann; Christiane Stahl-Hennig; Nicole Stolte; T Mühl; Michael Krawczak; M Spring; Dietmar Fuchs; Franz-Josef Kaup; Gerhard Hunsmann; Sieghart Sopper
Homozygosity for a conserved Mhc class II DQ-DRB haplotype is associated with rapid disease progression in simian immunodeficiency virus-infected macaques: results from a prospective study.
The Journal of infectious diseases 2000;182(3):716-24.
2000: Eleni Koutsilieri; Stefanie Czub; Carsten Scheller; Sieghart Sopper; Thomas Tatschner; Christiane Stahl-Hennig; Volker ter Meulen; Peter Riederer
Brain choline acetyltransferase reduction in SIV infection. An index of early dementia?
Neuroreport 2000;11(11):2391-3.
2000: Astrid Halbach; D Nierwetberg; Justus G Müller; Ursula Sauer; T Kerkau; Nicole Stolte; P Hofmann; Stefanie Czub; Volker ter Meulen; Sieghart Sopper
Total numbers of lymphocyte subsets in different lymph node regions of uninfected and SIV-infected macaques.
Journal of medical primatology 2000;29(3-4):148-57.
2000: M Demuth; Stefanie Czub; Ursula Sauer; Eleni Koutsilieri; Peter Ten Haaft; Jonathan Luke Heeney; Christiane Stahl-Hennig; Volker ter Meulen; Sieghart Sopper
Relationship between viral load in blood, cerebrospinal fluid, brain tissue and isolated microglia with neurological disease in macaques infected with different strains of SIV.
Journal of neurovirology 2000;6(3):187-201.
2000: Sieghart Sopper; Ursula Sauer; Justus G Müller; Christiane Stahl-Hennig; Volker ter Meulen
Early activation and proliferation of T cells in simian immunodeficiency virus-infected rhesus monkeys.
AIDS research and human retroviruses 2000;16(7):689-97.
2000: Björn R Gundlach; M G Lewis; Sieghart Sopper; T Schnell; Joseph Sodroski; Christiane Stahl-Hennig; Klaus Uberla
Evidence for recombination of live, attenuated immunodeficiency virus vaccine with challenge virus to a more virulent strain.
Journal of virology 2000;74(8):3537-42.
2000: Carsten Scheller; Sieghart Sopper; Christian Jassoy; Volker ter Meulen; Peter Riederer; Eleni Koutsilieri
Dopamine activates HIV in chronically infected T lymphoblasts.
Journal of neural transmission (Vienna, Austria : 1996) 2000;107(12):1483-9.
1999: A Eckert; Gisela Segond von Banchet; Sieghart Sopper; Marlen Petersen
Spatio-temporal pattern of induction of bradykinin receptors and inflammation in rat dorsal root ganglia after unilateral nerve ligation.
Pain 1999;83(3):487-97.
1999: Markus Czub; Stefanie Czub; G Gosztonyi; Eleni Koutsilieri; Sieghart Sopper; Justus G Müller; Manfred Gerlach; Peter Riederer; Volker ter Meulen
Effects of Selegiline in a retroviral rat model for neurodegenerative disease.
Journal of neurovirology 1999;5(5):458-64.
1999: Eleni Koutsilieri; Sieghart Sopper; Thoralf Heinemann; Carsten Scheller; J Lan; Christiane Stahl-Hennig; Volker ter Meulen; Peter Riederer; Manfred Gerlach
Involvement of microglia in cerebrospinal fluid glutamate increase in SIV-infected rhesus monkeys (Macaca mulatta).
AIDS research and human retroviruses 1999;15(5):471-7.
1999: Frank Kirchhoff; S Carl; Sieghart Sopper; Ulrike Sauermann; Kerstin Mätz-Rensing; Christiane Stahl-Hennig
Selection of the R17Y substitution in SIVmac239 nef coincided with a dramatic increase in plasma viremia and rapid progression to death.
Virology 1999;254(1):61-70.
1998: Sieghart Sopper; Ursula Sauer; S Hemm; M Demuth; Justus Müller; Christiane Stahl-Hennig; Gerhard Hunsmann; Volker ter Meulen; Rüdiger Dörries
Protective role of the virus-specific immune response for development of severe neurologic signs in simian immunodeficiency virus-infected macaques.
Journal of virology 1998;72(12):9940-7.
1998: Björn R Gundlach; S Reiprich; Sieghart Sopper; R E Means; Ulf Dittmer; Kerstin Mätz-Rensing; Christiane Stahl-Hennig; Klaus Uberla
Env-independent protection induced by live, attenuated simian immunodeficiency virus vaccines.
Journal of virology 1998;72(10):7846-51.
1997: Eleni Koutsilieri; Mario E Götz; Sieghart Sopper; Christiane Stahl-Hennig; Markus Czub; Volker ter Meulen; Peter Riederer
Monoamine metabolite levels in CSF of SIV-infected rhesus monkeys (Macaca mulatta).
Neuroreport 1997;8(17):3833-6.
1997: Sieghart Sopper; Christiane Stahl-Hennig; M Demuth; Ian Johnston; Rüdiger Dörries; Volker ter Meulen
Lymphocyte subsets and expression of differentiation markers in blood and lymphoid organs of rhesus monkeys.
Cytometry 1997;29(4):351-62.
1997: Eleni Koutsilieri; Mario E Götz; Sieghart Sopper; Ursula Sauer; M Demuth; Volker ter Meulen; Peter Riederer
Regulation of glutathione and cell toxicity following exposure to neurotropic substances and human immunodeficiency virus-1 in vitro.
Journal of neurovirology 1997;3(5):342-9.
1997: Martin Heinkelein; M Müller; O Kutsch; Sieghart Sopper; Christian Jassoy
Rapid and selective depletion of CD4+ T lymphocytes and preferential loss of memory cells on interaction of mononuclear cells with HIV-1 glycoprotein-expressing cells.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1997;16(2):74-82.
1997: H Linhart; Björn R Gundlach; Sieghart Sopper; Ulf Dittmer; Kerstin Mätz-Rensing; EM Kuhn; J Müller; Gerhard Hunsmann; Christiane Stahl-Hennig; Klaus Uberla
Live attenuated SIV vaccines are not effective in a postexposure vaccination model.
AIDS research and human retroviruses 1997;13(7):593-9.
1997: Björn R Gundlach; H Linhart; Ulf Dittmer; Sieghart Sopper; S Reiprich; Dietmar Fuchs; Bernhard Fleckenstein; Gerhard Hunsmann; Christiane Stahl-Hennig; Klaus Uberla
Construction, replication, and immunogenic properties of a simian immunodeficiency virus expressing interleukin-2.
Journal of virology 1997;71(3):2225-32.
1996: Eleni Koutsilieri; J Kornhuber; H J Degen; Klaus-Peter Lesch; Sieghart Sopper; Volker ter Meulen; Peter Riederer
U-373 MG glioblastoma and IMR-32 neuroblastoma cell lines express the dopamine and vesicular monoamine transporters.
Journal of neuroscience research 1996;45(3):269-75.
1996: Sieghart Sopper; M Demuth; Christiane Stahl-Hennig; Gerhard Hunsmann; Roland Plesker; Cheick Coulibaly; Stefanie Czub; M Ceska; Eleni Koutsilieri; Peter Riederer; R Brinkmann; M Katz; Volker ter Meulen
The effect of simian immunodeficiency virus infection in vitro and in vivo on the cytokine production of isolated microglia and peripheral macrophages from rhesus monkey.
Virology 1996;220(2):320-9.
1995: A Hein; Stefan Schwender; H Imrich; Sieghart Sopper; Markus Czub; Rüdiger Dörries
Phenotypic and functional characterization of CD8+ T lymphocytes from the central nervous system of rats with coronavirus JHM induced demyelinating encephalomyelitis.
Journal of neurovirology 1995;1(5-6):340-8.
1995: Martin Heinkelein; Sieghart Sopper; Christian Jassoy
Contact of human immunodeficiency virus type 1-infected and uninfected CD4+ T lymphocytes is highly cytolytic for both cells.
Journal of virology 1995;69(11):6925-31.
1995: J Hoch; Sabine M Lang; M Weeger; Christiane Stahl-Hennig; Cheick Coulibaly; Ulf Dittmer; Gerhard Hunsmann; Dietmar Fuchs; J Müller; Sieghart Sopper
vpr deletion mutant of simian immunodeficiency virus induces AIDS in rhesus monkeys.
Journal of virology 1995;69(8):4807-13.
1993: Sieghart Sopper; S Hemm; Jürgen Meixensberger; Cheick Coulibaly; Christiane Stahl-Hennig; Gerhard Hunsmann; Bernhard Fleckenstein; Volker ter Meulen; Rüdiger Dörries
Dynamics of the immune system response in cerebrospinal fluid and blood of SIVmac-infected rhesus monkeys.
Journal of medical primatology 1993;22(2-3):138-46.