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Hermona Soreq

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S Shenhar-Tsarfaty; Ludmila Shopin; Hermona Soreq; Saly Usher; N Waiskopf; S Berliner; Natan M Bornstein; Keren Ofek; Ya'acov Ritov; I Shapira; Einor Ben-Assayag
Atherosclerosis and arteriosclerosis parameters in stroke patients associate with paraoxonase polymorphism and esterase activities.
Keren Ofek; Hermona Soreq
Cholinergic involvement and manipulation approaches in multiple system disorders.
Shahar Barbash; Hermona Soreq
Statistically invalid classification of high throughput gene expression data.

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All Publications

2013: S Shenhar-Tsarfaty; Ludmila Shopin; Hermona Soreq; Saly Usher; N Waiskopf; S Berliner; Natan M Bornstein; Keren Ofek; Ya'acov Ritov; I Shapira; Einor Ben-Assayag
Atherosclerosis and arteriosclerosis parameters in stroke patients associate with paraoxonase polymorphism and esterase activities.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2013;20(6):891-8.
2013: Keren Ofek; Hermona Soreq
Cholinergic involvement and manipulation approaches in multiple system disorders.
Chemico-biological interactions 2013;203(1):113-9.
2013: Shahar Barbash; Hermona Soreq
Statistically invalid classification of high throughput gene expression data.
Scientific reports 2013;3():1102.
2013: Adi Alkalay; William J Jagust; Daniela Kaufer; Bruce L Miller; Gil D Rabinovici; Neha Agarwal; Gabriel Zimmerman; Hermona Soreq
Plasma acetylcholinesterase activity correlates with intracerebral β-amyloid load.
Current Alzheimer research 2013;10(1):48-56.
2012: Badi Sri Sailaja; Hermona Soreq; Gabriel Zimmerman; Dorit Cohen-Carmon; Eran Meshorer
Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(52):E3687-95.
2012: Jon Sussman; Yitzhak Wirguin; Slobodan Apolski; Zohar Argov; Vedrana Milic-Rasic; Hermona Soreq
Further developments with antisense treatment for myasthenia gravis.
Annals of the New York Academy of Sciences 2012;1275():13-6.
2012: Soo Young Kim; Hermona Soreq; Annamaria Vezzani; Marion Buckwalter; Daniela Kaufer
Blood-brain barrier dysfunction-induced inflammatory signaling in brain pathology and epileptogenesis.
Epilepsia 2012;53 Suppl 6():37-44.
2012: Keren Ofek; Karl Schoknecht; Alon Friedman; Uwe Heinemann; Naomi Melamed-Book; Hermona Soreq
Fluoxetine induces vasodilatation of cerebral arterioles by co-modulating NO/muscarinic signalling.
Journal of cellular and molecular medicine 2012;16(11):2736-44.
2012: Amit Berson; Alon Friedman; Yael Goll; David S Greenberg; Geula Hanin; Maya Ketzef; Galit Shaltiel; Shahar Barbash; Albert J Becker; Hermona Soreq
Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice.
EMBO molecular medicine 2012;4(8):730-42.
2012: Lilach Soreq; Hagai Bergman; Yael Goll; David S Greenberg; Zvi Israel; Hermona Soreq
Deep brain stimulation induces rapidly reversible transcript changes in Parkinson's leucocytes.
Journal of cellular and molecular medicine 2012;16(7):1496-507.
2012: Einor Ben-Assayag; A Sholmo Berliner; Orna Aizenstein; Eitan Auriel; Dafna Ben Baashat; Nir Giladi; Uri Goldbourt; Hen Hallevi; Jeff M Hausdorff; Talma Hendler; Noomi Katz; Efrat Kliper; Amos D Korczyn; Anat Mike; Itzhak Shapira; Shani Shenhar-Tsarfaty; Ludmila Shopin; Zahava Solomon; Hermona Soreq; Saly Usher; Natan M Bornstein
Predictors for poststroke outcomes: the Tel Aviv Brain Acute Stroke Cohort (TABASCO) study protocol.
International journal of stroke : official journal of the International Stroke Society 2012;7(4):341-7.
2012: Shahar Barbash; Hermona Soreq
Threshold-independent meta-analysis of Alzheimer's disease transcriptomes shows progressive changes in hippocampal functions, epigenetics and microRNA regulation.
Current Alzheimer research 2012;9(4):425-35.
2012: Lilach Soreq; Yoram Ben-Shaul; Hagai Bergman; Zvi Israel; Hermona Soreq
Meta-analysis of genetic and environmental Parkinson's disease models reveals a common role of mitochondrial protection pathways.
Neurobiology of disease 2012;45(3):1018-30.
2012: Shani Ben-Ari; David Samuel Greenberg; Eugenia Kovalev; Hanoch Meiri; Keren Ofek; Shahar Barbash; Hermona Soreq; Shai Shoham
Similar cation channels mediate protection from cerebellar exitotoxicity by exercise and inheritance.
Journal of cellular and molecular medicine 2012;16(3):555-68.
2012: Brian C Geyer; Jacki A Kilbourne; Tsafrir S Mor; Shahar Barbash; Shani Ben Ari; Hermona Soreq
Nicotinic stimulation induces Tristetraprolin over-production and attenuates inflammation in muscle.
Biochimica et biophysica acta 2012;1823(2):368-78.
2012: Karl Tsim; Hermona Soreq
Acetylcholinesterase: old questions and new developments.
Frontiers in molecular neuroscience 2012;5():101.
2012: Yehudit Gnatek; Yael Goll; Naim Najami; Hermona Soreq; Gabriel Zimmerman; Alon Friedman
Acetylcholinesterase loosens the brain's cholinergic anti-inflammatory response and promotes epileptogenesis.
Frontiers in molecular neuroscience 2012;5():66.
2012: Adi Gilboa-Geffen; Gunther Hartmann; Hermona Soreq
Stressing hematopoiesis and immunity: an acetylcholinesterase window into nervous and immune system interactions.
Frontiers in molecular neuroscience 2012;5():30.
2012: Lilach Soreq; Hagai Bergman; Zvi Israel; Hermona Soreq
Exon arrays reveal alternative splicing aberrations in Parkinson's disease leukocytes.
Neuro-degenerative diseases 2012;10(1-4):203-6.
2012: Liat Benmoyal-Segal; Yoram Ben-Shaul; Hagai Bergman; Sigal Aviel; Shani Ben-Ari; Tehila Ben-Moshe; Lilach Soreq; Hermona Soreq
Adaptive alternative splicing correlates with less environmental risk of parkinsonism.
Neuro-degenerative diseases 2012;9(2):87-98.
2011: Shani Shenhar-Tsarfaty; Einor Ben-Assayag; Shlomo Berliner; Natan M Bornstein; Hermona Soreq
Letter by Shenhar-Tsarfaty et al regarding article, "Autonomic shift and increased susceptibility to infections after acute intracerebral hemorrhage".
Stroke; a journal of cerebral circulation 2011;42(10):e559.
2011: Hermona Soreq; Yochai Wolf
NeurimmiRs: microRNAs in the neuroimmune interface.
Trends in molecular medicine 2011;17(10):548-55.
2011: Ronan M G Berg; Keren Ofek; Tavs Qvist; Hermona Soreq; Flemming Tofteng; Kirsten Møller
Cholinesterase modulations in patients with acute bacterial meningitis.
Scandinavian journal of clinical and laboratory investigation 2011;71(4):350-2.
2011: Ronan M G Berg; Hermona Soreq; Kirsten Møller
Effects of physostigmine on microcirculatory alterations during experimental endotoxemia.
Shock (Augusta, Ga.) 2011;35(5):537-8; author reply 538.
2011: Nir Waiskopf; Uri Banin; Itai Lieberman; Itzhak Shweky; Hermona Soreq
Quantum dot labeling of butyrylcholinesterase maintains substrate and inhibitor interactions and cell adherence features.
ACS chemical neuroscience 2011;2(3):141-50.
2011: Geula Hanin; Hermona Soreq
Cholinesterase-Targeting microRNAs Identified in silico Affect Specific Biological Processes.
Frontiers in molecular neuroscience 2011;4():28.
2010: Brian C Geyer; Latha Kannan; Pierre-Emmanuel Garnaud; Clarence A Broomfield; C Linn Cadieux; Irene Cherni; Sean M Hodgins; Shane A Kasten; Karli Kelley; Jacki A Kilbourne; Zeke P Oliver; Tamara C Otto; Ian Puffenberger; Tony E Reeves; Neil Robbins; Ryan R Woods; Hermona Soreq; David Lenz; david e lenz; Tsafrir S Mor
Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(47):20251-6.
2010: Debra Toiber; Garikoitz Azkona; Shani Ben-Ari; Nuria Torán; Hermona Soreq; Mara Dierssen
Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations.
Neurobiology of disease 2010;40(1):348-59.
2010: Brian C Geyer; Latha Kannan; Irene Cherni; Ryan R Woods; Hermona Soreq; Tsafrir S Mor
Transgenic plants as a source for the bioscavenging enzyme, human butyrylcholinesterase.
Plant biotechnology journal 2010;8(8):873-86.
2010: Erez Podoly; Geula Hanin; Hermona Soreq
Alanine-to-threonine substitutions and amyloid diseases: butyrylcholinesterase as a case study.
Chemico-biological interactions 2010;187(1-3):64-71.
2010: Einor Ben-Assayag; Shani Shenhar-Tsarfaty; Keren Ofek; Lilach Soreq; Irina Bova; Ludmila Shopin; Ronan M G Berg; Shlomo Berliner; Itzhak Shapira; Natan M Bornstein; Hermona Soreq
Serum cholinesterase activities distinguish between stroke patients and controls and predict 12-month mortality.
Molecular medicine (Cambridge, Mass.) 2010;16(7-8):278-86.
2010: Marco Sifringer; Daniela Brait; Ulrike Weichelt; Gabriel Zimmerman; Stefanie Endesfelder; Felix Brehmer; Clarissa von Haefen; Alon Friedman; Hermona Soreq; Ivo Bendix; Bettina Gerstner; Ursula Felderhoff-Mueser
Erythropoietin attenuates hyperoxia-induced oxidative stress in the developing rat brain.
Brain, behavior, and immunity 2010;24(5):792-9.
2010: David S Greenberg; Debra Toiber; Amit Berson; Hermona Soreq
Acetylcholinesterase variants in Alzheimer's disease: from neuroprotection to programmed cell death.
Neuro-degenerative diseases 2010;7(1-3):60-3.
2010: Ari Meerson; Luisa Cacheaux; Ki Ann Goosens; Robert M Sapolsky; Hermona Soreq; daniela kaufer
Changes in brain MicroRNAs contribute to cholinergic stress reactions.
Journal of molecular neuroscience : MN 2010;40(1-2):47-55.
2009: Iftach Shaked; Ari Meerson; Yochai Wolf; Ran Avni; David Greenberg; Adi Gilboa-Geffen; Hermona Soreq
MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase.
Immunity 2009;31(6):965-73.
2009: Debra Toiber; David S Greenberg; Hermona Soreq
Pro-apoptotic protein-protein interactions of the extended N-AChE terminus.
Journal of neural transmission (Vienna, Austria : 1996) 2009;116(11):1435-42.
2009: Erez Podoly; Deborah E Shalev; Shani Shenhar-Tsarfaty; Estelle R Bennett; Einor Ben-Assayag; Harvey Wilgus; Oded Livnah; Hermona Soreq
The butyrylcholinesterase K variant confers structurally derived risks for Alzheimer pathology.
The Journal of biological chemistry 2009;284(25):17170-9.
2009: Bettina Heinrich; Zhaiyi Zhang; Oleg Raitskin; Michael Hiller; Natalya Benderska; Annette M Hartmann; Laurent Bracco; David Elliott; Shani Ben-Ari; Hermona Soreq; Joseph Sperling; Ruth Sperling; Stefan Stamm
Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regions in pre-mRNA.
The Journal of biological chemistry 2009;284(21):14303-15.
2009: Shaul Karni; Hermona Soreq; Roded Sharan
A network-based method for predicting disease-causing genes.
Journal of computational biology : a journal of computational molecular cell biology 2009;16(2):181-9.
2008: Iftach Shaked; Gabriel Zimmerman; Hermona Soreq
Stress-induced alternative splicing modulations in brain and periphery: acetylcholinesterase as a case study.
Annals of the New York Academy of Sciences 2008;1148():269-81.
2008: Inbal Mor; Tal Bruck; David Greenberg; Amit Berson; Leticia Schreiber; Dan Grisaru; Hermona Soreq
Alternate AChE-R variants facilitate cellular metabolic activity and resistance to genotoxic stress through enolase and RACK1 interactions.
Chemico-biological interactions 2008;175(1-3):11-21.
2008: Lilach Soreq; Zvi Israel; Hagai Bergman; Hermona Soreq
Advanced microarray analysis highlights modified neuro-immune signaling in nucleated blood cells from Parkinson's disease patients.
Journal of neuroimmunology 2008;201-202():227-36.
2008: Hermona Soreq; Ehud Gazit
The structural basis of amyloid formation.
Current Alzheimer research 2008;5(3):232.
2008: Robert Adamec; David Head; Hermona Soreq; Jacqueline Blundell
The role of the read through variant of acetylcholinesterase in anxiogenic effects of predator stress in mice.
Behavioural brain research 2008;189(1):180-90.
2008: I Mor; Ella H Sklan; Erez Podoly; Marjorie Pick; M Kirschner; L Yogev; S Bar-Sheshet Itach; L Schreiber; Brian C Geyer; Tsafrir S Mor; D Grisaru; Hermona Soreq
Acetylcholinesterase-R increases germ cell apoptosis but enhances sperm motility.
Journal of cellular and molecular medicine 2008;12(2):479-95.
2008: Irit Shapira-Lichter; Benzion Beilin; Keren Ofek; Hanna Bessler; Michal Gruberger; Yehuda Shavit; Dan Seror; Galina Grinevich; Eldad Posner; Abraham Reichenberg; Hermona Soreq; Raz Yirmiya
Cytokines and cholinergic signals co-modulate surgical stress-induced changes in mood and memory.
Brain, behavior, and immunity 2008;22(3):388-98.
2008: Gabriel Zimmerman; Marleisje Njunting; Sebastian Ivens; Else A Tolner; Elsa Tolner; Christoph J Behrens; Miriam Gross; Hermona Soreq; Uwe Heinemann; Alon Friedman
Acetylcholine-induced seizure-like activity and modified cholinergic gene expression in chronically epileptic rats.
The European journal of neuroscience 2008;27(4):965-75.
2008: Hermona Soreq
Introduction: cholinesterases, from molecular complexity to non-hydrolytic functions.
The FEBS journal 2008;275(4):603.
2008: Debra Toiber; Amit Berson; David Greenberg; Naomi Melamed-Book; Sophia Diamant; Hermona Soreq
N-acetylcholinesterase-induced apoptosis in Alzheimer's disease.
PloS one 2008;3(9):e3108.
2008: Jon D Sussman; Zohar Argov; David McKee; Eli Hazum; Solli Brawer; Hermona Soreq
Antisense treatment for myasthenia gravis: experience with monarsen.
Annals of the New York Academy of Sciences 2008;1132():283-90.
2008: Lilach Soreq; Adi Gilboa-Geffen; Sonia Berrih-Aknin; Paul Lacoste; Saurav Guha; Eyal Soreq; Hagai Bergman; Hermona Soreq
Identifying alternative hyper-splicing signatures in MG-thymoma by exon arrays.
PloS one 2008;3(6):e2392.
2008: Erez Podoly; T Bruck; Sophia Diamant; Naomi Melamed-Book; A Weiss; Y Huang; Oded Livnah; Solomon Langermann; Harvey Wilgus; Hermona Soreq
Human recombinant butyrylcholinesterase purified from the milk of transgenic goats interacts with beta-amyloid fibrils and suppresses their formation in vitro.
Neuro-degenerative diseases 2008;5(3-4):232-6.
2008: Amit Berson; Marlen Knobloch; Mor Hanan; Sophia Diamant; Michal Sharoni; Daniel Schuppli; Brian C Geyer; Rivka Ravid; Tsafrir S Mor; Roger M Nitsch; Hermona Soreq
Changes in readthrough acetylcholinesterase expression modulate amyloid-beta pathology.
Brain : a journal of neurology 2008;131(Pt 1):109-19.
2007: John Concato; Mihaela Aslan; Margaret M Palmisano; Caroline Carney Doebbeling; Peter Peduzzi; Keren Ofek; Hermona Soreq; Bradley Doebbeling
Acetylcholinesterase activity in veterans of the first Gulf War.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2007;55(7):360-7.
2007: Keren Ofek; Karen S Krabbe; Tama Evron; Meir Debecco; Anders Rinnov Nielsen; Helle Brunnsgaad; Raz Yirmiya; Hermona Soreq; Bente Klarlund Pedersen
Cholinergic status modulations in human volunteers under acute inflammation.
Journal of molecular medicine (Berlin, Germany) 2007;85(11):1239-51.
2007: Tama Evron; Brian C Geyer; Irene Cherni; Mrinalini Muralidharan; Jacki A Kilbourne; Samuel P Fletcher; Hermona Soreq; Tsafrir S Mor
Plant-derived human acetylcholinesterase-R provides protection from lethal organophosphate poisoning and its chronic aftermath.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(11):2961-9.
2007: Zohar Argov; D McKee; Samuel Agus; S Brawer; N Shlomowitz; O Ben Yoseph; Hermona Soreq; J D Sussman
Treatment of human myasthenia gravis with oral antisense suppression of acetylcholinesterase.
Neurology 2007;69(7):699-700.
2007: Chava Perry; Marjorie Pick; Erez Podoly; A Gilboa-Geffen; G Zimmerman; Ella H Sklan; Y Ben-Shaul; Sophia Diamant; Hermona Soreq
Acetylcholinesterase/C terminal binding protein interactions modify Ikaros functions, causing T lymphopenia.
Leukemia 2007;21(7):1472-80.
2007: Amir Dori; Gal Ifergane; Tal Saar-Levy; Marina Bersudsky; Inbal Mor; Hermona Soreq; Itzhak Wirguin
Readthrough acetylcholinesterase in inflammation-associated neuropathies.
Life sciences 2007;80(24-25):2369-74.
2007: Adi Gilboa-Geffen; Paul P Lacoste; Lilach Soreq; Geraldine Cizeron-Clairac; Rozen Le Panse; Frederique Truffault; Iftach Shaked; Hermona Soreq; Sonia Berrih-Aknin
The thymic theme of acetylcholinesterase splice variants in myasthenia gravis.
Blood 2007;109(10):4383-91.
2007: Tama Evron; David Greenberg; Tsafrir S Mor; Hermona Soreq
Adaptive changes in acetylcholinesterase gene expression as mediators of recovery from chemical and biological insults.
Toxicology 2007;233(1-3):97-107.
2007: Rinat Kehat; Esther Zemel; Nicolas Cuenca; Tama Evron; Debra Toiber; Anat Loewenstein; Hermona Soreq; Ido Perlman
A novel isoform of acetylcholinesterase exacerbates photoreceptors death after photic stress.
Investigative ophthalmology & visual science 2007;48(3):1290-7.
2007: Hermona Soreq; Alik Honigman
It is all about resolution. Meeting report based upon presentations at the 10th International Global BioMillennium 2006 symposium on molecular cell biology (Tbilisi, Georgia).
The FEBS journal 2007;274(4):924-7.
2007: Noa Farchi; Keren Ofek; Erez Podoly; Haiheng Dong; Yun-Yan Xiang; Sophia Diamant; Oded Livnah; Jingxin Li; Binyamin Hochner; Wei-Yang Lu; Hermona Soreq
Peripheral site acetylcholinesterase blockade induces RACK1-associated neuronal remodeling.
Neuro-degenerative diseases 2007;4(2-3):171-84.
2007: Brian C Geyer; Samuel P Fletcher; Tagan A Griffin; Michael J Lopker; Hermona Soreq; Tsafrir S Mor
Translational control of recombinant human acetylcholinesterase accumulation in plants.
BMC biotechnology 2007;7():27.
2007: Noa Farchi; Shai Shoham; Binyamin Hochner; Hermona Soreq
Impaired hippocampal plasticity and errors in cognitive performance in mice with maladaptive AChE splice site selection.
The European journal of neuroscience 2007;25(1):87-98.
2006: Gabriel Zimmerman; Hermona Soreq
Termination and beyond: acetylcholinesterase as a modulator of synaptic transmission.
Cell and tissue research 2006;326(2):655-69.
2006: Amir Dori; Hermona Soreq
Neuromuscular therapeutics by RNA-targeted suppression of ACHE gene expression.
Annals of the New York Academy of Sciences 2006;1082():77-90.
2006: Ella H Sklan; Amit Berson; Klara R Birikh; Amos Gutnick; Or Shahar; Shai Shoham; Hermona Soreq
Acetylcholinesterase modulates stress-induced motor responses through catalytic and noncatalytic properties.
Biological psychiatry 2006;60(7):741-51.
2006: R Orie Browne; Liat Ben Moyal-Segal; Dominik Zumsteg; Yaron David; ora kofman; Andrea Berger; Hermona Soreq; Alon Friedman
Coding region paraoxonase polymorphisms dictate accentuated neuronal reactions in chronic, sub-threshold pesticide exposure.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(10):1733-5.
2006: Sophia Diamant; Erez Podoly; Assaf Friedler; Hagai Ligumsky; Oded Livnah; Hermona Soreq
Butyrylcholinesterase attenuates amyloid fibril formation in vitro.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(23):8628-33.
2006: Yoram Ben-Shaul; Liat Benmoyal-Segal; Shani Ben-Ari; Hagai Bergman; Hermona Soreq
Adaptive acetylcholinesterase splicing patterns attenuate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice.
The European journal of neuroscience 2006;23(11):2915-22.
2006: Liat Benmoyal-Segal; Hermona Soreq
Gene-environment interactions in sporadic Parkinson's disease.
Journal of neurochemistry 2006;97(6):1740-55.
2006: Cinthya Guimaraes-Sternberg; Ari Meerson; Iftach Shaked; Hermona Soreq
MicroRNA modulation of megakaryoblast fate involves cholinergic signaling.
Leukemia research 2006;30(5):583-95.
2006: Marjorie Pick; Chava Perry; Tsvee Lapidot; Cinthya Guimaraes-Sternberg; Elizabeth Naparstek; varda deutsch; Hermona Soreq
Stress-induced cholinergic signaling promotes inflammation-associated thrombopoiesis.
Blood 2006;107(8):3397-406.
2006: Shani Ben-Ari; Debra Toiber; Aldema S Sas; Hermona Soreq; Yoram Ben-Shaul
Modulated splicing-associated gene expression in P19 cells expressing distinct acetylcholinesterase splice variants.
Journal of neurochemistry 2006;97 Suppl 1():24-34.
2006: Eran Meshorer; Hermona Soreq
Virtues and woes of AChE alternative splicing in stress-related neuropathologies.
Trends in neurosciences 2006;29(4):216-24.
2006: Ella H Sklan; Erez Podoly; Hermona Soreq
RACK1 has the nerve to act: structure meets function in the nervous system.
Progress in neurobiology 2006;78(2):117-34.
2006: Gabriel Zimmerman; Hermona Soreq
Readthrough acetylcholinesterase: a multifaceted inducer of stress reactions.
Journal of molecular neuroscience : MN 2006;30(1-2):197-200.
2006: Amir Dori; Hermona Soreq
ARP, the cleavable C-terminal peptide of "readthrough" acetylcholinesterase, promotes neuronal development and plasticity.
Journal of molecular neuroscience : MN 2006;28(3):247-55.
2006: Dan Grisaru; Marjorie Pick; Chava Perry; Ella H Sklan; Ronit Almog; Ilan Goldberg; Elizabeth Naparstek; Joseph B Lessing; Hermona Soreq; varda deutsch
Hydrolytic and nonenzymatic functions of acetylcholinesterase comodulate hemopoietic stress responses.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(1):27-35.
2005: Mrinalini Muralidharan; Hermona Soreq; Tsafrir S Mor
Characterizing pea acetylcholinesterase.
Chemico-biological interactions 2005;157-158():406-7.
2005: A Salmon; Christina Erb; Eran Meshorer; Dalia Ginzberg; Y Adani; Ishai Rabinovitz; Gil Amitai; Hermona Soreq
Muscarinic modulations of neuronal anticholinesterase responses.
Chemico-biological interactions 2005;157-158():105-13.
2005: Brian C Geyer; Mrinalini Muralidharan; Irene Cherni; Jeffrey Doran; Samuel P Fletcher; Tama Evron; Hermona Soreq; Tsafrir S Mor
Purification of transgenic plant-derived recombinant human acetylcholinesterase-R.
Chemico-biological interactions 2005;157-158():331-4.
2005: Eran Meshorer; Boris Bryk; Debra Toiber; J Cohen; Erez Podoly; A Dori; Hermona Soreq
SC35 promotes sustainable stress-induced alternative splicing of neuronal acetylcholinesterase mRNA.
Molecular psychiatry 2005;10(11):985-97.
2005: Tina M Rees; Amit Berson; Ella H Sklan; Linda Younkin; Steven G Younkin; Stephen Brimijoin; Hermona Soreq
Memory deficits correlating with acetylcholinesterase splice shift and amyloid burden in doubly transgenic mice.
Current Alzheimer research 2005;2(3):291-300.
2005: Debra Toiber; Hermona Soreq
Cellular stress reactions as putative cholinergic links in Alzheimer's disease.
Neurochemical research 2005;30(6-7):909-19.
2005: Eran Meshorer; Inbal E Biton; Yoram Ben-Shaul; Shani Ben-Ari; Yaniv Assaf; Hermona Soreq; Yoram Cohen
Chronic cholinergic imbalances promote brain diffusion and transport abnormalities.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(8):910-22.
2005: Yehuda Pollak; Adi Gilboa; Ofra Ben-Menachem; Tamir Ben-Hur; Hermona Soreq; Raz Yirmiya
Acetylcholinesterase inhibitors reduce brain and blood interleukin-1beta production.
Annals of neurology 2005;57(5):741-5.
2005: Amir Dori; Jonathan Cohen; William F Silverman; Yaakov Pollack; Hermona Soreq
Functional manipulations of acetylcholinesterase splice variants highlight alternative splicing contributions to murine neocortical development.
Cerebral cortex (New York, N.Y. : 1991) 2005;15(4):419-30.
2005: Yoram Ben-Shaul; Hagai Bergman; Hermona Soreq
Identifying subtle interrelated changes in functional gene categories using continuous measures of gene expression.
Bioinformatics (Oxford, England) 2005;21(7):1129-37.
2005: Boris Bryk; Liat Benmoyal-Segal; Erez Podoly; Oded Livnah; Arik Eisenkraft; Shai Luria; Amir Cohen; Yoav Yehezkelli; Ariel Hourvitz; Hermona Soreq
Inherited and acquired interactions between ACHE and PON1 polymorphisms modulate plasma acetylcholinesterase and paraoxonase activities.
Journal of neurochemistry 2005;92(5):1216-27.
2005: Liat Benmoyal-Segal; Tatiana Vander; Sagiv Shifman; Boris Bryk; Richard P Ebstein; Esther-Lee Marcus; Jochanan Stessman; Saurav Guha; Yuval Herishanu; Alon Friedman; Hermona Soreq
Acetylcholinesterase/paraoxonase interactions increase the risk of insecticide-induced Parkinson's disease.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(3):452-4.
2005: Stefan Stamm; Shani Ben-Ari; Ilona Rafalska-Metcalf; Yesheng Tang; Zhaiyi Zhang; Debra Toiber; Thangavel Alphonse Thanaraj; Hermona Soreq
Function of alternative splicing.
Gene 2005;344():1-20.
2005: Tama Evron; Liat Ben Moyal-Segal; Noa Lamm; Adi Geffen; Hermona Soreq
RNA-targeted suppression of stress-induced allostasis in primate spinal cord neurons.
Neuro-degenerative diseases 2005;2(1):16-27.
2004: Marjorie Pick; Cesar Flores-Flores; Dan Grisaru; Susana Shochat; varda deutsch; Hermona Soreq
Blood-cell-specific acetylcholinesterase splice variations under changing stimuli.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2004;22(7):523-31.
2004: Haiheng Dong; Yun-Yan Xiang; Noa Farchi; William Ju; Yaojiong Wu; Liwen Chen; Yutian Wang; Binyamin Hochner; Burton Yang; Hermona Soreq; Wei-Yang Lu
Excessive expression of acetylcholinesterase impairs glutamatergic synaptogenesis in hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(41):8950-60.
2004: Chava Perry; Hermona Soreq
Organophosphate risk of leukemogenesis.
Leukemia research 2004;28(9):905-6.
2004: Eran Meshorer; Debra Toiber; Dror Zurel; Iman Sahly; Amir Dori; Emanuela Cagnano; Letizia Schreiber; Dan Grisaru; François Tronche; Hermona Soreq
Combinatorial complexity of 5' alternative acetylcholinesterase transcripts and protein products.
The Journal of biological chemistry 2004;279(28):29740-51.
2004: Marjorie Pick; Cesar Flores-Flores; Hermona Soreq
From brain to blood: alternative splicing evidence for the cholinergic basis of Mammalian stress responses.
Annals of the New York Academy of Sciences 2004;1018():85-98.
2004: Samuel P Fletcher; Brian C Geyer; Amy Smith; Tama Evron; Lokesh Joshi; Hermona Soreq; Tsafrir S Mor
Tissue distribution of cholinesterases and anticholinesterases in native and transgenic tomato plants.
Plant molecular biology 2004;55(1):33-43.
2004: Chava Perry; Ella H Sklan; Hermona Soreq
CREB regulates AChE-R-induced proliferation of human glioblastoma cells.
Neoplasia (New York, N.Y.) 2004;6(3):279-86.
2004: Ella H Sklan; Alexander Lowenthal; Mira Korner; Ya'acov Ritov; Daniel M Landers; Tuomo Rankinen; Claude Bouchard; Arthur S Leon; Treva Rice; D C Rao; Jack H Wilmore; James Skinner; Hermona Soreq
Acetylcholinesterase/paraoxonase genotype and expression predict anxiety scores in Health, Risk Factors, Exercise Training, and Genetics study.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(15):5512-7.
2004: Ingrid Nijholt; Noa Farchi; Min-Jeong Kye; Ella H Sklan; Shai Shoham; B Verbeure; D Owen; Binyamin Hochner; Joachim Spiess; Hermona Soreq; Thomas Blank
Stress-induced alternative splicing of acetylcholinesterase results in enhanced fear memory and long-term potentiation.
Molecular psychiatry 2004;9(2):174-83.
2003: David Glick; Hermona Soreq
Ethics, public policy and behavioral genetics.
The Israel Medical Association journal : IMAJ 2003;5(2):83-6.
2003: Talma Brenner; Yasmine Hamra-Amitay; Tama Evron; Neli Boneva; Shlomo Seidman; Hermona Soreq
The role of readthrough acetylcholinesterase in the pathophysiology of myasthenia gravis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(2):214-22.
2003: Klara R Birikh; Ella H Sklan; Shai Shoham; Hermona Soreq
Interaction of "readthrough" acetylcholinesterase with RACK1 and PKCbeta II correlates with intensified fear-induced conflict behavior.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(1):283-8.
2003: Osnat Cohen; Abraham Reichenberg; Chava Perry; Dalia Ginzberg; Thomas Pollmächer; Hermona Soreq; Raz Yirmiya
Endotoxin-induced changes in human working and declarative memory associate with cleavage of plasma "readthrough" acetylcholinesterase.
Journal of molecular neuroscience : MN 2003;21(3):199-212.
2003: Noa Farchi; Hermona Soreq; Binyamin Hochner
Chronic acetylcholinesterase overexpression induces multilevelled aberrations in mouse neuromuscular physiology.
The Journal of physiology 2003;546(Pt 1):165-73.
2002: Chava Perry; Ella H Sklan; Klara R Birikh; Michael Shapira; Leonor Trejo; Amiram Eldor; Hermona Soreq
Complex regulation of acetylcholinesterase gene expression in human brain tumors.
Oncogene 2002;21(55):8428-41.
2002: Peter Stoilov; Eran Meshorer; Marieta Gencheva; David Glick; Hermona Soreq; Stefan Stamm
Defects in pre-mRNA processing as causes of and predisposition to diseases.
DNA and cell biology 2002;21(11):803-18.
2002: Eran Meshorer; Hermona Soreq
Pre-mRNA splicing modulations in senescence.
Aging cell 2002;1(1):10-6.
2002: varda deutsch; Marjorie Pick; Chava Perry; Dan Grisaru; Yoram Hemo; Dita Golan-Hadari; Alastair Grant; Amiram Eldor; Hermona Soreq
The stress-associated acetylcholinesterase variant AChE-R is expressed in human CD34(+) hematopoietic progenitors and its C-terminal peptide ARP promotes their proliferation.
Experimental hematology 2002;30(10):1153-61.
2002: Chava Perry; Hermona Soreq
Transcriptional regulation of erythropoiesis. Fine tuning of combinatorial multi-domain elements.
European journal of biochemistry / FEBS 2002;269(15):3607-18.
2002: Marie M Svedberg; Anne-Lie Svensson; Mary Johnson; Mandy Lee; Osnat Cohen; Jennifer A Court; Hermona Soreq; Elaine K Perry; agneta nordberg
Upregulation of neuronal nicotinic receptor subunits alpha4, beta2, and alpha7 in transgenic mice overexpressing human acetylcholinesterase.
Journal of molecular neuroscience : MN 2002;18(3):211-22.
2002: Chava Perry; Amiram Eldor; Hermona Soreq
Runx1/AML1 in leukemia: disrupted association with diverse protein partners.
Leukemia research 2002;26(3):221-8.
2002: Eran Meshorer; Christina Erb; Roi Gazit; Lev Pavlovsky; daniela kaufer; Alon Friedman; David Glick; Nissim Ben-Arie; Hermona Soreq
Alternative splicing and neuritic mRNA translocation under long-term neuronal hypersensitivity.
Science (New York, N.Y.) 2002;295(5554):508-12.
2002: Cesar Flores-Flores; Ahuva Nissim; Susana Shochat; Hermona Soreq
Development of human antibody fragments directed towards synaptic acetylcholinesterase using a semi-synthetic phage display library.
Journal of neural transmission. Supplementum 2002;(62):165-79.
2002: Osnat Cohen; Christina Erb; Dalia Ginzberg; Yehuda Pollak; Shlomo Seidman; Shai Shoham; Raz Yirmiya; Hermona Soreq
Neuronal overexpression of "readthrough" acetylcholinesterase is associated with antisense-suppressible behavioral impairments.
Molecular psychiatry 2002;7(8):874-85.
2001: A D Grant; M Shapira; Hermona Soreq
Genomic dissection reveals locus response to stress for mammalian acetylcholinesterase.
Cellular and molecular neurobiology 2001;21(6):783-97.
2001: Tsafrir S Mor; M Sternfeld; Hermona Soreq; Charles J Arntzen; Hugh S Mason
Expression of recombinant human acetylcholinesterase in transgenic tomato plants.
Biotechnology and bioengineering 2001;75(3):259-66.
2001: Chava Perry; Hermona Soreq
The leukemic effect of anticholinesterases.
Leukemia research 2001;25(11):1027-8.
2001: I Mor; Dan Grisaru; L Titelbaum; Tama Evron; Carmelit Richler; Jacob Wahrman; Meira Sternfeld; L Yogev; N Meiri; Shlomo Seidman; Hermona Soreq
Modified testicular expression of stress-associated "readthrough" acetylcholinesterase predicts male infertility.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(11):2039-41.
2001: M Shapira; C K Thompson; Hermona Soreq; Gene E Robinson
Changes in neuronal acetylcholinesterase gene expression and division of labor in honey bee colonies.
Journal of molecular neuroscience : MN 2001;17(1):1-12.
2001: Dan Grisaru; varda deutsch; M Shapira; Marjorie Pick; Meira Sternfeld; Naomi Melamed-Book; daniela kaufer; N Galyam; M J Gait; D Owen; J B Lessing; Amiram Eldor; Hermona Soreq
ARP, a peptide derived from the stress-associated acetylcholinesterase variant, has hematopoietic growth promoting activities.
Molecular medicine (Cambridge, Mass.) 2001;7(2):93-105.
2001: N Galyam; Dan Grisaru; M Grifman; Naomi Melamed-Book; F Eckstein; Shlomo Seidman; Amiram Eldor; Hermona Soreq
Complex host cell responses to antisense suppression of ACHE gene expression.
Antisense & nucleic acid drug development 2001;11(1):51-7.
2000: Meira Sternfeld; Shai Shoham; O Klein; Cesar Flores-Flores; Tama Evron; G H Idelson; D Kitsberg; James W Patrick; Hermona Soreq
Excess "read-through" acetylcholinesterase attenuates but the "synaptic" variant intensifies neurodeterioration correlates.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(15):8647-52.
2000: Hermona Soreq; Shlomo Seidman
Anti-sense approach to anticholinesterase therapeutics.
The Israel Medical Association journal : IMAJ 2000;2 Suppl():81-5.
2000: M Shapira; A Grant; Mira Korner; Hermona Soreq
Genomic and transcriptional characterization of the human ACHE locus: complex involvement with acquired and inherited diseases.
The Israel Medical Association journal : IMAJ 2000;2(6):470-3.
2000: M Shapira; I Tur-Kaspa; L Bosgraaf; Nelly Livni; A D Grant; Dan Grisaru; Mira Korner; Richard Ebstein; Hermona Soreq
A transcription-activating polymorphism in the ACHE promoter associated with acute sensitivity to anti-acetylcholinesterases.
Human molecular genetics 2000;9(9):1273-81.
2000: Efrat Lev-Lehman; Tama Evron; Ron S Broide; Eran Meshorer; Ilana Ariel; Shlomo Seidman; Hermona Soreq
Synaptogenesis and myopathy under acetylcholinesterase overexpression.
Journal of molecular neuroscience : MN 2000;14(1-2):93-105.
2000: Esther Shohami; daniela kaufer; Y Chen; Shlomo Seidman; Osnat Cohen; Dalia Ginzberg; Naomi Melamed-Book; Raz Yirmiya; Hermona Soreq
Antisense prevention of neuronal damages following head injury in mice.
Journal of molecular medicine (Berlin, Germany) 2000;78(4):228-36.
1999: daniela kaufer; Hermona Soreq
Tracking cholinergic pathways from psychological and chemical stressors to variable neurodeterioration paradigms.
Current opinion in neurology 1999;12(6):739-43.
1999: Dan Grisaru; Meira Sternfeld; Amiram Eldor; David Glick; Hermona Soreq
Structural roles of acetylcholinesterase variants in biology and pathology.
European journal of biochemistry / FEBS 1999;264(3):672-86.
1999: Ron S Broide; M Grifman; A Loewenstein; Dan Grisaru; Rina Timberg; J Stone; M Shani; James W Patrick; Hermona Soreq
Manipulations of ACHE gene expression suggest non-catalytic involvement of acetylcholinesterase in the functioning of mammalian photoreceptors but not in retinal degeneration.
Brain research. Molecular brain research 1999;71(2):137-48.
1999: Shlomo Seidman; F Eckstein; M Grifman; Hermona Soreq
Antisense technologies have a future fighting neurodegenerative diseases.
Antisense & nucleic acid drug development 1999;9(4):333-40.
1999: daniela kaufer; Alon Friedman; Shlomo Seidman; Hermona Soreq
Anticholinesterases induce multigenic transcriptional feedback response suppressing cholinergic neurotransmission.
Chemico-biological interactions 1999;119-120():349-60.
1999: Dan Grisaru; Efrat Lev-Lehman; M Shapira; E Chaikin; J B Lessing; Amiram Eldor; F Eckstein; Hermona Soreq
Human osteogenesis involves differentiation-dependent increases in the morphogenically active 3' alternative splicing variant of acetylcholinesterase.
Molecular and cellular biology 1999;19(1):788-95.
1998: M Shapira; S Seidman; Nelly Livni; Hermona Soreq
In vivo and in vitro resistance to multiple anticholinesterases in Xenopus laevis tadpoles.
Toxicology letters 1998;102-103():205-9.
1998: M Grifman; N Galyam; Shlomo Seidman; Hermona Soreq
Functional redundancy of acetylcholinesterase and neuroligin in mammalian neuritogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13935-40.
1998: Hermona Soreq
Cholinergic mechanisms--tenth international symposium. 1-5 September 1998, Arcachon, France.
IDrugs : the investigational drugs journal 1998;1(7):787-93.
1998: Meira Sternfeld; J D Patrick; Hermona Soreq
Position effect variegations and brain-specific silencing in transgenic mice overexpressing human acetylcholinesterase variants.
Journal of physiology, Paris 1998;92(3-4):249-55.
1998: daniela kaufer; Alon Friedman; Shlomo Seidman; Hermona Soreq
Acute stress facilitates long-lasting changes in cholinergic gene expression.
Nature 1998;393(6683):373-7.
1998: C Andres; S Seidman; Ronen Beeri; Rina Timberg; Hermona Soreq
Transgenic acetylcholinesterase induces enlargement of murine neuromuscular junctions but leaves spinal cord synapses intact.
Neurochemistry international 1998;32(5-6):449-56.
1998: Meira Sternfeld; Guo-Li Ming; Hongjun Song; K Sela; Rina Timberg; Mu-ming Poo; Hermona Soreq
Acetylcholinesterase enhances neurite growth and synapse development through alternative contributions of its hydrolytic capacity, core protein, and variable C termini.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(4):1240-9.
1997: Ronen Beeri; N Le Novère; R Mervis; T Huberman; Grauer Ettie; Jean-Pierre Changeux; Hermona Soreq
Enhanced hemicholinium binding and attenuated dendrite branching in cognitively impaired acetylcholinesterase-transgenic mice.
Journal of neurochemistry 1997;69(6):2441-51.
1997: M Grifman; A Arbel; Dalia Ginzberg; David Glick; Sharona Elgavish; B Shaanan; Hermona Soreq
In vitro phosphorylation of acetylcholinesterase at non-consensus protein kinase A sites enhances the rate of acetylcholine hydrolysis.
Brain research. Molecular brain research 1997;51(1-2):179-87.
1997: M Grifman; Hermona Soreq
Differentiation intensifies the susceptibility of pheochromocytoma cells to antisense oligodeoxynucleotide-dependent suppression of acetylcholinesterase activity.
Antisense & nucleic acid drug development 1997;7(4):351-9.
1997: C Andres; Ronen Beeri; Alon Friedman; Efrat Lev-Lehman; S Henis; Rina Timberg; M Shani; Hermona Soreq
Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Ibeta gene expression followed by late-onset neuromotor deterioration.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(15):8173-8.
1997: Meira Sternfeld; Jacob Rachmilewitz; Y Loewenstein-Lichtenstein; C Andres; Rina Timberg; Shani Ben-Ari; C Glick; Hermona Soreq; H Zakut
Normal and atypical butyrylcholinesterases in placental development, function, and malfunction.
Cellular and molecular neurobiology 1997;17(3):315-32.
1997: Efrat Lev-Lehman; varda deutsch; Amiram Eldor; Hermona Soreq
Immature human megakaryocytes produce nuclear-associated acetylcholinesterase.
Blood 1997;89(10):3644-53.
1997: Klara R Birikh; Yuri A Berlin; Hermona Soreq; Fritz Eckstein
Probing accessible sites for ribozymes on human acetylcholinesterase RNA.
RNA (New York, N.Y.) 1997;3(4):429-37.
1997: Ron S Broide; M Grifman; M Shapira; Dalia Ginzberg; Hermona Soreq
Genetic manipulations of cholinergic communication reveal trans-acting control mechanisms over acetylcholine receptors.
Journal of receptor and signal transduction research 1997;17(1-3):279-91.
1996: Y Loewenstein-Lichtenstein; David Glick; N Gluzman; Meira Sternfeld; HV Zakut; Hermona Soreq
Overlapping drug interaction sites of human butyrylcholinesterase dissected by site-directed mutagenesis.
Molecular pharmacology 1996;50(6):1423-31.
1996: Alon Friedman; daniela kaufer; J Shemer; Israel Hendler; Hermona Soreq; Ilan Tur-Kaspa
Pyridostigmine brain penetration under stress enhances neuronal excitability and induces early immediate transcriptional response.
Nature medicine 1996;2(12):1382-5.
1996: C Andres; Ronen Beeri; T Huberman; M Shani; Hermona Soreq
Cholinergic drug resistance and impaired spatial learning in transgenic mice overexpressing human brain acetylcholinesterase.
Progress in brain research 1996;109():265-72.
1996: R Karpel; Meira Sternfeld; Dalia Ginzberg; Eva Guhl; A Graessmann; Hermona Soreq
Overexpression of alternative human acetylcholinesterase forms modulates process extensions in cultured glioma cells.
Journal of neurochemistry 1996;66(1):114-23.
1995: Y Loewenstein-Lichtenstein; M Schwarz; David Glick; B Nørgaard-Pedersen; HV Zakut; Hermona Soreq
Genetic predisposition to adverse consequences of anti-cholinesterases in 'atypical' BCHE carriers.
Nature medicine 1995;1(10):1082-5.
1995: Ronen Beeri; C Andres; Efrat Lev-Lehman; Rina Timberg; T Huberman; M Shani; Hermona Soreq
Transgenic expression of human acetylcholinesterase induces progressive cognitive deterioration in mice.
Current biology : CB 1995;5(9):1063-71.
1995: M Schwarz; Y Loewenstein-Lichtenstein; David Glick; J Liao; B Norgaard-Pedersen; Hermona Soreq
Successive organophosphate inhibition and oxime reactivation reveals distinct responses of recombinant human cholinesterase variants.
Brain research. Molecular brain research 1995;31(1-2):101-10.
1995: Shlomo Seidman; Meira Sternfeld; R Ben Aziz-Aloya; Rina Timberg; D Kaufer-Nachum; Hermona Soreq
Synaptic and epidermal accumulations of human acetylcholinesterase are encoded by alternative 3'-terminal exons.
Molecular and cellular biology 1995;15(6):2993-3002.
1995: M Schwarz; David Glick; Y Loewenstein; Hermona Soreq
Engineering of human cholinesterases explains and predicts diverse consequences of administration of various drugs and poisons.
Pharmacology & therapeutics 1995;67(2):283-322.
1994: Efrat Lev-Lehman; A el-Tamer; A Yaron; M Grifman; Dalia Ginzberg; I Hanin; Hermona Soreq
Cholinotoxic effects on acetylcholinesterase gene expression are associated with brain-region specific alterations in G,C-rich transcripts.
Brain research 1994;661(1-2):75-82.
1994: D Patinkin; Efrat Lev-Lehman; HV Zakut; F Eckstein; Hermona Soreq
Antisense inhibition of butyrylcholinesterase gene expression predicts adverse hematopoietic consequences to cholinesterase inhibitors.
Cellular and molecular neurobiology 1994;14(5):459-73.
1994: M Shapira; Shlomo Seidman; Meira Sternfeld; Rina Timberg; daniela kaufer; J Patrick; Hermona Soreq
Transgenic engineering of neuromuscular junctions in Xenopus laevis embryos transiently overexpressing key cholinergic proteins.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):9072-6.
1994: Hermona Soreq; D Patinkin; Efrat Lev-Lehman; M Grifman; Dalia Ginzberg; F Eckstein; HV Zakut
Antisense oligonucleotide inhibition of acetylcholinesterase gene expression induces progenitor cell expansion and suppresses hematopoietic apoptosis ex vivo.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(17):7907-11.
1994: G Ehrlich; Dalia Ginzberg; Y Loewenstein; David Glick; Batsheva Kerem; S Ben-Ari; HV Zakut; Hermona Soreq
Population diversity and distinct haplotype frequencies associated with ACHE and BCHE genes of Israeli Jews from trans-Caucasian Georgia and from Europe.
Genomics 1994;22(2):288-95.
1994: Shlomo Seidman; R B Aziz-Aloya; Rina Timberg; Y Loewenstein; Baruch Velan; A Shafferman; J Liao; B Norgaard-Pedersen; Urs Brodbeck; Hermona Soreq
Overexpressed monomeric human acetylcholinesterase induces subtle ultrastructural modifications in developing neuromuscular junctions of Xenopus laevis embryos.
Journal of neurochemistry 1994;62(5):1670-81.
1994: Efrat Lev-Lehman; Dalia Ginzberg; G Hornreich; G Ehrlich; A Meshorer; F Eckstein; Hermona Soreq; HV Zakut
Antisense inhibition of acetylcholinesterase gene expression causes transient hematopoietic alterations in vivo.
Gene therapy 1994;1(2):127-35.
1994: R Karpel; R Ben Aziz-Aloya; Meira Sternfeld; G Ehrlich; Dalia Ginzberg; paola Tarroni; F Clementi; HV Zakut; Hermona Soreq
Expression of three alternative acetylcholinesterase messenger RNAs in human tumor cell lines of different tissue origins.
Experimental cell research 1994;210(2):268-77.
1994: Averell Gnatt; Y Loewenstein; A Yaron; M Schwarz; Hermona Soreq
Site-directed mutagenesis of active site residues reveals plasticity of human butyrylcholinesterase in substrate and inhibitor interactions.
Journal of neurochemistry 1994;62(2):749-55.
1994: Ronen Beeri; Averell Gnatt; Y Lapidot-Lifson; Dalia Ginzberg; M Shani; Hermona Soreq; HV Zakut
Testicular amplification and impaired transmission of human butyrylcholinesterase cDNA in transgenic mice.
Human reproduction (Oxford, England) 1994;9(2):284-92.
1994: Hermona Soreq; G Ehrlich; M Schwarz; Y Loewenstein; David Glick; HV Zakut
Mutations and impaired expression in the ACHE and BCHE genes: neurological implications.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1994;48(5-6):253-9.
1994: G Ehrlich; D Patinkin; Dalia Ginzberg; HV Zakut; F Eckstein; Hermona Soreq
Use of partially phosphorothioated "antisense" oligodeoxynucleotides for sequence-dependent modulation of hematopoiesis in culture.
Antisense research and development 1994;4(3):173-83.
1993: Y Loewenstein; Averell Gnatt; L F Neville; Hermona Soreq
Chimeric human cholinesterase. Identification of interaction sites responsible for recognition of acetyl- or butyrylcholinesterase-specific ligands.
Journal of molecular biology 1993;234(2):289-96.
1993: Y Loewenstein; Averell Gnatt; L F Neville; HV Zakut; Hermona Soreq
Structure-function relationship studies in human cholinesterases reveal genomic origins for individual variations in cholinergic drug responses.
Progress in neuro-psychopharmacology & biological psychiatry 1993;17(6):905-26.
1993: Y Loewenstein; M Denarie; HV Zakut; Hermona Soreq
Molecular dissection of cholinesterase domains responsible for carbamate toxicity.
Chemico-biological interactions 1993;87(1-3):209-16.
1993: R Ben Aziz-Aloya; Shlomo Seidman; Rina Timberg; Meira Sternfeld; HV Zakut; Hermona Soreq
Expression of a human acetylcholinesterase promoter-reporter construct in developing neuromuscular junctions of Xenopus embryos.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(6):2471-5.
1993: R Ben Aziz-Aloya; Meira Sternfeld; Hermona Soreq
Promoter elements and alternative splicing in the human ACHE gene.
Progress in brain research 1993;98():147-53.
1992: Hermona Soreq; Averell Gnatt; Y Loewenstein; L F Neville
Excavations into the active-site gorge of cholinesterases.
Trends in biochemical sciences 1992;17(9):353-8.
1992: G Ehrlich; E Viegas-Pequignot; Dalia Ginzberg; L Sindel; Hermona Soreq; HV Zakut
Mapping the human acetylcholinesterase gene to chromosome 7q22 by fluorescent in situ hybridization coupled with selective PCR amplification from a somatic hybrid cell panel and chromosome-sorted DNA libraries.
Genomics 1992;13(4):1192-7.
1992: HV Zakut; Y Lapidot-Lifson; Ronen Beeri; A Ballin; Hermona Soreq
In vivo gene amplification in non-cancerous cells: cholinesterase genes and oncogenes amplify in thrombocytopenia associated with lupus erythematosus.
Mutation research 1992;276(3):275-84.
1992: L F Neville; Averell Gnatt; Y Loewenstein; Shlomo Seidman; G Ehrlich; Hermona Soreq
Intramolecular relationships in cholinesterases revealed by oocyte expression of site-directed and natural variants of human BCHE.
The EMBO journal 1992;11(4):1641-9.
1992: Y Lapidot-Lifson; D Patinkin; C A Prody; G Ehrlich; Shlomo Seidman; R Ben-Aziz; F Benseler; F Eckstein; HV Zakut; Hermona Soreq
Cloning and antisense oligodeoxynucleotide inhibition of a human homolog of cdc2 required in hematopoiesis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(2):579-83.
1991: Hermona Soreq; Y Lapidot-Lifson; HV Zakut
A role for cholinesterases in tumorigenesis?
Cancer cells (Cold Spring Harbor, N.Y. : 1989) 1991;3(12):511-6.
1991: HV Zakut; Judy Lieman-Hurwitz; R Zamir; L Sindell; Dalia Ginzberg; Hermona Soreq
Chorionic villus cDNA library displays expression of butyrylcholinesterase: putative genetic disposition for ecological danger.
Prenatal diagnosis 1991;11(8):597-607.
1991: Averell Gnatt; Dalia Ginzberg; Judy Lieman-Hurwitz; R Zamir; HV Zakut; Hermona Soreq
Human acetylcholinesterase and butyrylcholinesterase are encoded by two distinct genes.
Cellular and molecular neurobiology 1991;11(1):91-104.
1990: L F Neville; Averell Gnatt; R Padan; Shlomo Seidman; Hermona Soreq
Anionic site interactions in human butyrylcholinesterase disrupted by two single point mutations.
The Journal of biological chemistry 1990;265(34):20735-8.
1990: Hermona Soreq; R Ben-Aziz; C A Prody; Shlomo Seidman; Averell Gnatt; L Neville; Judy Lieman-Hurwitz; Efrat Lev-Lehman; Dalia Ginzberg; Y Lipidot-Lifson
Molecular cloning and construction of the coding region for human acetylcholinesterase reveals a G + C-rich attenuating structure.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):9688-92.
1990: L F Neville; Averell Gnatt; Y Loewenstein; Hermona Soreq
Aspartate-70 to glycine substitution confers resistance to naturally occurring and synthetic anionic-site ligands on in-ovo produced human butyrylcholinesterase.
Journal of neuroscience research 1990;27(4):452-60.
1990: D Patinkin; Shlomo Seidman; F Eckstein; F Benseler; HV Zakut; Hermona Soreq
Manipulations of cholinesterase gene expression modulate murine megakaryocytopoiesis in vitro.
Molecular and cellular biology 1990;10(11):6046-50.
1990: HV Zakut; G Ehrlich; A Ayalon; C A Prody; Gustavo Malinger; Shlomo Seidman; Dalia Ginzberg; R Kehlenbach; Hermona Soreq
Acetylcholinesterase and butyrylcholinesterase genes coamplify in primary ovarian carcinomas.
The Journal of clinical investigation 1990;86(3):900-8.
1990: R Ben Aziz; Hermona Soreq
Improving poor in vitro transcription from G,C-rich genes.
Nucleic acids research 1990;18(11):3418.
1990: Averell Gnatt; C A Prody; R Zamir; Judy Lieman-Hurwitz; HV Zakut; Hermona Soreq
Expression of alternatively terminated unusual human butyrylcholinesterase messenger RNA transcripts, mapping to chromosome 3q26-ter, in nervous system tumors.
Cancer research 1990;50(7):1983-7.
1990: Hermona Soreq; HV Zakut
Amplification of butyrylcholinesterase and acetylcholinesterase genes in normal and tumor tissues: putative relationship to organophosphorous poisoning.
Pharmaceutical research 1990;7(1):1-7.
1990: Hermona Soreq; HV Zakut
Expression and in vivo amplification of the human acetylcholinesterase and butyrylcholinesterase genes.
Progress in brain research 1990;84():51-61.
1990: Shlomo Seidman; Hermona Soreq
Coinjection of Xenopus oocytes with cDNA-produced and native mRNAs: a molecular biological approach to the tissue-specific processing of human cholinesterases.
International review of neurobiology 1990;32():107-39.
1989: Nissim Benvenisty; T Shoshani; Y Farkash; Hermona Soreq; Lea Reshef
trans activation of rat phosphoenolpyruvate carboxykinase (GTP) gene expression by micro-coinjection of rat liver mRNA in Xenopus laevis oocytes.
Molecular and cellular biology 1989;9(11):5244-7.
1989: Nurit Ballas; S Broido; Hermona Soreq; Abraham Loyter
Efficient functioning of plant promoters and poly(A) sites in Xenopus oocytes.
Nucleic acids research 1989;17(19):7891-903.
1989: P A Dreyfus; Shlomo Seidman; M Pincon-Raymond; M Murawsky; François Rieger; E Schejter; HV Zakut; Hermona Soreq
Tissue-specific processing and polarized compartmentalization of clone-produced cholinesterase in microinjected Xenopus oocytes.
Cellular and molecular neurobiology 1989;9(3):323-41.
1989: Hermona Soreq; Shlomo Seidman; P A Dreyfus; D Zevin-Sonkin; HV Zakut
Expression and tissue-specific assembly of human butyrylcholine esterase in microinjected Xenopus laevis oocytes.
The Journal of biological chemistry 1989;264(18):10608-13.
1989: Y Lapidot-Lifson; C A Prody; Dalia Ginzberg; D Meytes; HV Zakut; Hermona Soreq
Coamplification of human acetylcholinesterase and butyrylcholinesterase genes in blood cells: correlation with various leukemias and abnormal megakaryocytopoiesis.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(12):4715-9.
1989: C A Prody; P Dreyfus; R Zamir; HV Zakut; Hermona Soreq
De novo amplification within a "silent" human cholinesterase gene in a family subjected to prolonged exposure to organophosphorous insecticides.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(2):690-4.
1989: Hermona Soreq; C A Prody
Sequence similarities between human acetylcholinesterase and related proteins: putative implications for therapy of anticholinesterase intoxication.
Progress in clinical and biological research 1989;289():347-59.
1989: Gustavo Malinger; HV Zakut; Hermona Soreq
Cholinoceptive properties of human primordial, preantral, and antral oocytes: in situ hybridization and biochemical evidence for expression of cholinesterase genes.
Journal of molecular neuroscience : MN 1989;1(2):77-84.
1988: P Dreyfus; D Zevin-Sonkin; Shlomo Seidman; C Prody; Rivka Zisling; HV Zakut; Hermona Soreq
Cross-homologies and structural differences between human cholinesterases revealed by antibodies against cDNA-produced human butyrylcholinesterase peptides.
Journal of neurochemistry 1988;51(6):1858-67.
1988: Y Farkash; Hermona Soreq; Joseph Orly
Biosynthesis of catalytically active rat testosterone 5 alpha-reductase in microinjected Xenopus oocytes: evidence for tissue-specific differences in translatable mRNA.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(16):5824-8.
1988: HV Zakut; L Even; S Birkenfeld; G Malinger; Rivka Zisling; Hermona Soreq
Modified properties of serum cholinesterases in primary carcinomas.
Cancer 1988;61(4):727-37.
1987: Hermona Soreq; R Zamir; D Zevin-Sonkin; HV Zakut
Human cholinesterase genes localized by hybridization to chromosomes 3 and 16.
Human genetics 1987;77(4):325-8.
1987: Hermona Soreq; G Malinger; HV Zakut
Expression of cholinesterase genes in human oocytes revealed by in-situ hybridization.
Human reproduction (Oxford, England) 1987;2(8):689-93.
1987: C A Prody; D Zevin-Sonkin; Averell Gnatt; O Goldberg; Hermona Soreq
Isolation and characterization of full-length cDNA clones coding for cholinesterase from fetal human tissues.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(11):3555-9.
1987: Hermona Soreq; Averell Gnatt
Molecular biological search for human genes encoding cholinesterases.
Molecular neurobiology 1987;1(1-2):47-80.
1986: Hermona Soreq; K M Dziegielewska; D Zevin-Sonkin; HV Zakut
The use of mRNA translation in vitro and in ovo followed by crossed immunoelectrophoretic autoradiography to study the biosynthesis of human cholinesterases.
Cellular and molecular neurobiology 1986;6(3):227-37.
1986: K M Dziegielewska; N R Saunders; E J Schejter; HV Zakut; D Zevin-Sonkin; Rivka Zisling; Hermona Soreq
Synthesis of plasma proteins in fetal, adult, and neoplastic human brain tissue.
Developmental biology 1986;115(1):93-104.
1986: C Prody; D Zevin-Sonkin; Averell Gnatt; R Koch; Rivka Zisling; O Goldberg; Hermona Soreq
Use of synthetic oligodeoxynucleotide probes for the isolation of a human cholinesterase cDNA clone.
Journal of neuroscience research 1986;16(1):25-35.
1986: Ester Fride; Hermona Soreq; Marta Weinstock
Are the effects of gestational stress on motor development and cerebellar cholinesterase activity mediated prenatally?
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1986;4(5):407-13.
1985: Hermona Soreq; D Zevin-Sonkin; Adi Avni; L M Hall; P Spierer
A human acetylcholinesterase gene identified by homology to the Ace region of Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(6):1827-31.