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Gina Sosinsky

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Angela C Cone; Maryann E Martone; Eliana Scemes; Cinzia Ambrosi; Gina E Sosinsky
A comparative antibody analysis of pannexin1 expression in four rat brain regions reveals varying subcellular localizations.
Elena Dolmatova; Cinzia Ambrosi; Jennifer R Baum; Daniela Boassa; Kimberly Keith; Maria I Kontaridis; Paul L Sorgen; Gina E Sosinsky; Gaelle Spagnol; Heather S Duffy
Cardiomyocyte ATP release through pannexin 1 aids in early fibroblast activation.
Jeffrey D Martell; Vamsi K Mootha; Thomas L Poulos; Yasemin Sancak; Gina E Sosinsky; Thomas J Deerinck; Mark H Ellisman; Alice Y Ting
Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy.

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All Publications

2013: Angela C Cone; Maryann E Martone; Eliana Scemes; Cinzia Ambrosi; Gina E Sosinsky
A comparative antibody analysis of pannexin1 expression in four rat brain regions reveals varying subcellular localizations.
Frontiers in pharmacology 2013;4():6.
2012: Elena Dolmatova; Cinzia Ambrosi; Jennifer R Baum; Daniela Boassa; Kimberly Keith; Maria I Kontaridis; Paul L Sorgen; Gina E Sosinsky; Gaelle Spagnol; Heather S Duffy
Cardiomyocyte ATP release through pannexin 1 aids in early fibroblast activation.
American journal of physiology. Heart and circulatory physiology 2012;303(10):H1208-18.
2012: Jeffrey D Martell; Vamsi K Mootha; Thomas L Poulos; Yasemin Sancak; Gina E Sosinsky; Thomas J Deerinck; Mark H Ellisman; Alice Y Ting
Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy.
Nature biotechnology 2012;30(11):1143-8.
2012: Yong-Chun Yu; Gina E Sosinsky; Xing-Hua Yao; Keith N Brown; She Chen; Yinghui Fu; Kate P Gao; Shuijin He; Kun Huang; Jian Ma; Song-Hai Shi
Preferential electrical coupling regulates neocortical lineage-dependent microcircuit assembly.
Nature 2012;486(7401):113-7.
2012: Mark H Ellisman; Xiaokun Shu; Thomas J Deerinck; Gina E Sosinsky
Picking faces out of a crowd: genetic labels for identification of proteins in correlated light and electron microscopy imaging.
Methods in cell biology 2012;111():139-55.
2011: Gina E Sosinsky; david spray; Roger J Thompson; Hong-Bo Zhao; Rolf Dermietzel; Heather S Duffy; Dale W Laird; Brian MacVicar; Christian C Naus; Silvia Penuela; Eliana Scemes; Daniela Boassa; Gerhard Dahl
Pannexin channels are not gap junction hemichannels.
Channels (Austin, Tex.) 2011;5(3):193-7.
2011: Atsunori Oshima; Kazutoshi Tani; Masoud M Toloue; Yoko Hiroaki; Amy Smock; Sayaka Inukai; Angela Cone; Bruce Nicholson; Gina E Sosinsky; Yoshinori Fujiyoshi
Asymmetric configurations and N-terminal rearrangements in connexin26 gap junction channels.
Journal of molecular biology 2011;405(3):724-35.
2010: Daniela Boassa; Joell L Solan; Adrian Papas; Perry Thornton; Paul D Lampe; Gina E Sosinsky
Trafficking and recycling of the connexin43 gap junction protein during mitosis.
Traffic (Copenhagen, Denmark) 2010;11(11):1471-86.
2010: Cinzia Ambrosi; Oliver Gassmann; Jennifer N Pranskevich; Daniela Boassa; Amy Smock; Junjie Wang; Gerhard Dahl; Claudia Steinem; Gina E Sosinsky
Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other.
The Journal of biological chemistry 2010;285(32):24420-31.
2010: Cinzia Ambrosi; Daniela Boassa; Jennifer Pranskevich; Amy Smock; Atsunori Oshima; Ji Xu; Bruce Nicholson; Gina E Sosinsky
Analysis of four connexin26 mutant gap junctions and hemichannels reveals variations in hexamer stability.
Biophysical journal 2010;98(9):1809-19.
2009: Alexandra Lichtenstein; Guido M Gaietta; Thomas J Deerinck; John Crum; Gina E Sosinsky; Eric C Beyer; Viviana M Berthoud
The cytoplasmic accumulations of the cataract-associated mutant, Connexin50P88S, are long-lived and form in the endoplasmic reticulum.
Experimental eye research 2009;88(3):600-9.
2008: Courtney L Lopreore; Thomas M Bartol; Jay S Coggan; Daniel X Keller; Gina E Sosinsky; Mark H Ellisman; Terrence J Sejnowski
Computational modeling of three-dimensional electrodiffusion in biological systems: application to the node of Ranvier.
Biophysical journal 2008;95(6):2624-35.
2008: Daniela Boassa; Feng Qiu; Gerhard Dahl; Gina E Sosinsky
Trafficking dynamics of glycosylated pannexin 1 proteins.
Cell communication & adhesion 2008;15(1):119-32.
2008: Atsunori Oshima; Kazutoshi Tani; Yoko Hiroaki; Yoshinori Fujiyoshi; Gina E Sosinsky
Projection structure of a N-terminal deletion mutant of connexin 26 channel with decreased central pore density.
Cell communication & adhesion 2008;15(1):85-93.
2008: Guy A Perkins; Gina E Sosinsky; Sassan Ghassemzadeh; Alex Perez; Ying Z Jones; Mark H Ellisman
Electron tomographic analysis of cytoskeletal cross-bridges in the paranodal region of the node of Ranvier in peripheral nerves.
Journal of structural biology 2008;161(3):469-80.
2008: Jason Lanman; John Crum; Thomas J Deerinck; Guido M Gaietta; Anette Schneemann; Gina E Sosinsky; Mark H Ellisman; John E Johnson
Visualizing flock house virus infection in Drosophila cells with correlated fluorescence and electron microscopy.
Journal of structural biology 2008;161(3):439-46.
2008: Gina E Sosinsky; John Crum; Ying Z Jones; Jason Lanman; Benjamin Smarr; Masako Terada; Maryann E Martone; Thomas J Deerinck; John E Johnson; Mark H Ellisman
The combination of chemical fixation procedures with high pressure freezing and freeze substitution preserves highly labile tissue ultrastructure for electron tomography applications.
Journal of structural biology 2008;161(3):359-71.
2007: Gina E Sosinsky; Joell L Solan; Guido Gaietta; Lucy Ngan; Grace J Lee; Mason R Mackey; Paul D Lampe
The C-terminus of connexin43 adopts different conformations in the Golgi and gap junction as detected with structure-specific antibodies.
The Biochemical journal 2007;408(3):375-85.
2007: Daniela Boassa; Cinzia Ambrosi; Feng Qiu; Gerhard Dahl; Guido Gaietta; Gina E Sosinsky
Pannexin1 channels contain a glycosylation site that targets the hexamer to the plasma membrane.
The Journal of biological chemistry 2007;282(43):31733-43.
2007: Atsunori Oshima; Kazutoshi Tani; Yoko Hiroaki; Yoshinori Fujiyoshi; Gina E Sosinsky
Three-dimensional structure of a human connexin26 gap junction channel reveals a plug in the vestibule.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(24):10034-9.
2007: Jinshu Yu; Christian A Bippes; Galen M Hand; Daniel Müller; Gina E Sosinsky
Aminosulfonate modulated pH-induced conformational changes in connexin26 hemichannels.
The Journal of biological chemistry 2007;282(12):8895-904.
2007: Gina E Sosinsky; Ben N G Giepmans; Thomas J Deerinck; Guido Gaietta; Mark H Ellisman
Markers for correlated light and electron microscopy.
Methods in cell biology 2007;79():575-91.
2006: Derek Beahm; Atsunori Oshima; Guido Gaietta; Galen M Hand; Amy E Smock; Shoshanna N Zucker; Masoud M Toloue; Anjana Chandrasekhar; Bruce Nicholson; Gina E Sosinsky
Mutation of a conserved threonine in the third transmembrane helix of alpha- and beta-connexins creates a dominant-negative closed gap junction channel.
The Journal of biological chemistry 2006;281(12):7994-8009.
2005: Gina E Sosinsky; Bruce Nicholson
Structural organization of gap junction channels.
Biochimica et biophysica acta 2005;1711(2):99-125.
2005: Gina E Sosinsky; Thomas J Deerinck; Rocco Greco; Casey H Buitenhuys; Thomas M Bartol; Mark H Ellisman
Development of a model for microphysiological simulations: small nodes of ranvier from peripheral nerves of mice reconstructed by electron tomography.
Neuroinformatics 2005;3(2):133-62.
2003: Gina E Sosinsky; Guido Gaietta; Galen M Hand; Thomas J Deerinck; Areum Han; Mason Mackey; Stephen R Adams; James C Bouwer; Roger Y Tsien; Mark H Ellisman
Tetracysteine genetic tags complexed with biarsenical ligands as a tool for investigating gap junction structure and dynamics.
Cell communication & adhesion 2003;10(4-6):181-6.
2002: Daniel J Müller; Galen M Hand; Andreas Engel; Gina E Sosinsky
Conformational changes in surface structures of isolated connexin 26 gap junctions.
The EMBO journal 2002;21(14):3598-607.
2002: Guido Gaietta; Thomas J Deerinck; Stephen R Adams; James C Bouwer; Oded Tour; Dale W Laird; Gina E Sosinsky; Roger Y Tsien; Mark H Ellisman
Multicolor and electron microscopic imaging of connexin trafficking.
Science (New York, N.Y.) 2002;296(5567):503-7.
2002: Maryann E Martone; Amarnath Gupta; Mona Wong; Xufei Qian; Gina E Sosinsky; Bertram Ludäscher; Mark H Ellisman
A cell-centered database for electron tomographic data.
Journal of structural biology 2002;138(1-2):145-55.
2002: Galen M Hand; Daniel J Müller; Bruce Nicholson; Andreas Engel; Gina E Sosinsky
Isolation and characterization of gap junctions from tissue culture cells.
Journal of molecular biology 2002;315(4):587-600.
2001: Galen M Hand; Maryann E Martone; A Stelljes; Mark H Ellisman; Gina E Sosinsky
Specific labeling of connexin43 in NRK cells using tyramide-based signal amplification and fluorescence photooxidation.
Microscopy research and technique 2001;52(3):331-43.
2001: Gina E Sosinsky; Guy A Perkins
Purification of gap junctions.
Methods in molecular biology (Clifton, N.J.) 2001;154():57-75.
2000: Gina E Sosinsky; Guy A Perkins
Electron crystallographic methods for investigating gap junction structure.
Methods (San Diego, Calif.) 2000;20(2):140-55.
1999: Gina E Sosinsky; T S Baker; Galen M Hand; Mark H Ellisman
The Electron Microscopy Outreach Program: A Web-based resource for research and education.
Journal of structural biology 1999;125(2-3):246-52.
1998: Guy A Perkins; D A Goodenough; Gina E Sosinsky
Formation of the gap junction intercellular channel requires a 30 degree rotation for interdigitating two apposing connexons.
Journal of molecular biology 1998;277(2):171-7.
1997: G Perkins; D Goodenough; Gina E Sosinsky
Three-dimensional structure of the gap junction connexon.
Biophysical journal 1997;72(2 Pt 1):533-44.
1995: Gina E Sosinsky
Mixing of connexins in gap junction membrane channels.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(20):9210-4.
1995: S Ghoshroy; D A Goodenough; Gina E Sosinsky
Preparation, characterization, and structure of half gap junctional layers split with urea and EGTA.
The Journal of membrane biology 1995;146(1):15-28.
1994: DJ Cabral-Lilly; Gina E Sosinsky; R A Reed; M R McDermott; GG Shipley
Orientation of cholera toxin bound to model membranes.
Biophysical journal 1994;66(4):935-41.
1994: N R Francis; Gina E Sosinsky; D Thomas; David J DeRosier
Isolation, characterization and structure of bacterial flagellar motors containing the switch complex.
Journal of molecular biology 1994;235(4):1261-70.
1992: Gina E Sosinsky; N R Francis; David J DeRosier; J S Wall; M N Simon; James F Hainfeld
Mass determination and estimation of subunit stoichiometry of the bacterial hook-basal body flagellar complex of Salmonella typhimurium by scanning transmission electron microscopy.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(11):4801-5.
1992: Gina E Sosinsky; N R Francis; M Joanne B Stallmeyer; David J DeRosier
Substructure of the flagellar basal body of Salmonella typhimurium.
Journal of molecular biology 1992;223(1):171-84.
1992: Gina E Sosinsky
Image analysis of gap junction structures.
Electron microscopy reviews 1992;5(1):59-76.
1991: DJ Cabral-Lilly; George N Phillips; Gina E Sosinsky; L Melanson; S Chacko; Carolyn Cohen
Structural studies of tropomyosin by cryoelectron microscopy and x-ray diffraction.
Biophysical journal 1991;59(4):805-14.
1990: Gina E Sosinsky; T S Baker; Donald L D Caspar; D A Goodenough
Correlation analysis of gap junction lattice images.
Biophysical journal 1990;58(5):1213-26.
1989: M Joanne B Stallmeyer; K M Hahnenberger; Gina E Sosinsky; L Shapiro; David J DeRosier
Image reconstruction of the flagellar basal body of Caulobacter crescentus.
Journal of molecular biology 1989;205(3):511-8.
1988: Gina E Sosinsky; J C Jésior; Donald L D Caspar; D A Goodenough
Gap junction structures. VIII. Membrane cross-sections.
Biophysical journal 1988;53(5):709-22.
1985: T S Baker; Gina E Sosinsky; Donald L D Caspar; C Gall; D A Goodenough
Gap junction structures. VII. Analysis of connexon images obtained with cationic and anionic negative stains.
Journal of molecular biology 1985;184(1):81-98.