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David Sosnovik

Research Profile

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Magnetic Resonance Imaging

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Chemicals & Drugs

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Image Processing, Computer-Assisted

Occupations

Magnetics

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TOP 3
Howard H Chen; Hoonsung Cho; Lee Josephson; Ronglih Liao; Brett Marinelli; Choukri Mekkaoui; Matthias Nahrendorf; Soeun Ngoy; Peter Waterman; David E Sosnovik
Fluorescence tomography of rapamycin-induced autophagy and cardioprotection in vivo.
Mihály Károlyi; Gary Liew; Pal Maurovich-Horvat; Masataka Nakano; Fumiyuki Otsuka; Christopher L Schlett; Harald Seifarth; Guangping Dai; Craig J Goergen; Udo Hoffmann; Shuning Huang; Paul Stolzmann; Renu Virmani; David E Sosnovik
Classification of coronary atherosclerotic plaques ex vivo with T1, T2, and ultrashort echo time CMR.
Hoonsung Cho; Peng Huang; David Alcantara; Sean B Andersson; Howard H Chen; Umar Mahmood; Rahul A Sheth; David E Sosnovik; Hushan Yuan; Lee Josephson
Fluorochrome-functionalized nanoparticles for imaging DNA in biological systems.

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All Publications

2013: Howard H Chen; Hoonsung Cho; Lee Josephson; Ronglih Liao; Brett Marinelli; Choukri Mekkaoui; Matthias Nahrendorf; Soeun Ngoy; Peter Waterman; David E Sosnovik
Fluorescence tomography of rapamycin-induced autophagy and cardioprotection in vivo.
Circulation. Cardiovascular imaging 2013;6(3):441-7.
2013: Mihály Károlyi; Gary Liew; Pal Maurovich-Horvat; Masataka Nakano; Fumiyuki Otsuka; Christopher L Schlett; Harald Seifarth; Guangping Dai; Craig J Goergen; Udo Hoffmann; Shuning Huang; Paul Stolzmann; Renu Virmani; David E Sosnovik
Classification of coronary atherosclerotic plaques ex vivo with T1, T2, and ultrashort echo time CMR.
JACC. Cardiovascular imaging 2013;6(4):466-74.
2013: Hoonsung Cho; Peng Huang; David Alcantara; Sean B Andersson; Howard H Chen; Umar Mahmood; Rahul A Sheth; David E Sosnovik; Hushan Yuan; Lee Josephson
Fluorochrome-functionalized nanoparticles for imaging DNA in biological systems.
ACS nano 2013;7(3):2032-41.
2012: Craig J Goergen; Eng H Lo; Emiri T Mandeville; Harsha Radhakrishnan; Sava Sakadžić; David E Sosnovik; Vivek J Srinivasan
Optical coherence tractography using intrinsic contrast.
Optics letters 2012;37(18):3882-4.
2012: David E Sosnovik; Matthias Nahrendorf
Cells and iron oxide nanoparticles on the move: magnetic resonance imaging of monocyte homing and myocardial inflammation in patients with ST-elevation myocardial infarction.
Circulation. Cardiovascular imaging 2012;5(5):551-4.
2012: David E Sosnovik; Matthias Nahrendorf; Peter Caravan
Science to practice: how will myocardial inflammation be imaged with MR imaging?
Radiology 2012;264(2):309-11.
2012: David Alcantara; Howard H Chen; Hoonsung Cho; Craig J Goergen; Yanyan Guo; David E Sosnovik; Hushan Yuan; Lee Josephson
Fluorochrome-functionalized magnetic nanoparticles for high-sensitivity monitoring of the polymerase chain reaction by magnetic resonance.
Angewandte Chemie (International ed. in English) 2012;51(28):6904-7.
2012: Craig J Goergen; Alexei Bogdanov; Howard H Chen; David E Sosnovik; Anand T N Kumar
In vivo fluorescence lifetime detection of an activatable probe in infarcted myocardium.
Journal of biomedical optics 2012;17(5):056001.
2012: Howard H Chen; Yan Feng; Lee Josephson; Stanley Y Shaw; Wei Chao; Ming Zhang; David E Sosnovik
Protective effect of the apoptosis-sensing nanoparticle AnxCLIO-Cy5.5.
Nanomedicine : nanotechnology, biology, and medicine 2012;8(3):291-8.
2012: Laura-Ann McGill; Choukri Mekkaoui; Sonia Nielles-Vallespin; Sanjay K Prasad; Michael Roughton; Andrew D Scott; David E Sosnovik; Peter Speier; Ranil de Silva; Thorsten Feiweier; Pedro Ferreira; David N Firmin; Peter D Gatehouse; S Yen Ho; Tevfik F Ismail; Philip Kilner; Karen P McCarthy; Dudley J Pennell
Reproducibility of in-vivo diffusion tensor cardiovascular magnetic resonance in hypertrophic cardiomyopathy.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 2012;14():86.
2012: Choukri Mekkaoui; Timothy G Reese; Jeremy N Ruskin; Howard H Chen; Guangping Dai; Udo Hoffmann; Shuning Huang; Marcel P Jackowski; William J Kostis; Pal Maurovich-Horvat; Aravinda Thiagalingam; David E Sosnovik
Fiber architecture in remodeled myocardium revealed with a quantitative diffusion CMR tractography framework and histological validation.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 2012;14():70.
2012: Howard H Chen; Lee Josephson; Hushan Yuan; David E Sosnovik
Theranostic Imaging of the Kinases and Proteases that Modulate Cell Death and Survival.
Theranostics 2012;2(2):148-55.
2011: Shuning Huang; Lee Josephson; Ronglih Liao; Choukri Mekkaoui; Soeun Ngoy; Daniel T Schuhle; Peter Caravan; Howard H Chen; Guangping Dai; Hushan Yuan; David E Sosnovik
Molecular MRI of acute necrosis with a novel DNA-binding gadolinium chelate: kinetics of cell death and clearance in infarcted myocardium.
Circulation. Cardiovascular imaging 2011;4(6):729-37.
2011: Yan Li; Rui Si; David E Sosnovik; E Wang; H Shaw Warren; Ming Zhang; Lin Zou; Howard H Chen; Yan Feng; Wei Chao
Myocardial ischemia activates an injurious innate immune signaling via cardiac heat shock protein 60 and Toll-like receptor 4.
The Journal of biological chemistry 2011;286(36):31308-19.
2011: Matthias Nahrendorf; David E Sosnovik
Science to practice: will magnetic guidance of microbubbles play a role in clinical molecular imaging?
Radiology 2011;260(2):309-10.
2011: Craig J Goergen; David E Sosnovik
From molecules to myofibers: multiscale imaging of the myocardium.
Journal of cardiovascular translational research 2011;4(4):493-503.
2011: Natalia C Berry; David E Sosnovik
Cardiomyocyte death: insights from molecular and microstructural magnetic resonance imaging.
Pediatric cardiology 2011;32(3):290-6.
2011: Howard H Chen; Lee Josephson; David E Sosnovik
Imaging of apoptosis in the heart with nanoparticle technology.
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 2011;3(1):86-99.
2010: Florian Leuschner; Peter Panizzi; Isabel Chico-Calero; Won Woo Lee; Takuya Ueno; Virna Cortez-Retamozo; Peter Waterman; Rostic Gorbatov; Brett Marinelli; Yoshiko Iwamoto; Aleksey Chudnovskiy; Jose-Luiz Figueiredo; David E Sosnovik; Mikaël J Pittet; Filip K Swirski; Ralph Weissleder; Matthias Nahrendorf
Angiotensin-converting enzyme inhibition prevents the release of monocytes from their splenic reservoir in mice with myocardial infarction.
Circulation research 2010;107(11):1364-73.
2010: Christopher M Kramer; Albert J Sinusas; David E Sosnovik; Brent A French; Frank M Bengel
Multimodality imaging of myocardial injury and remodeling.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51 Suppl 1():107S-121S.
2010: Peter Panizzi; Filip K Swirski; Jose-Luiz Figueiredo; Peter Waterman; David E Sosnovik; Elena Aikawa; Peter Libby; Mikael Pittet; Ralph Weissleder; Matthias Nahrendorf
Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis.
Journal of the American College of Cardiology 2010;55(15):1629-38.
2009: David E Sosnovik; Matthias Nahrendorf; Peter Panizzi; Takashi Matsui; Elena Aikawa; Guangping Dai; Ling Li; Fred Reynolds; Gerald W Dorn; Ralph Weissleder; Lee Josephson; Anthony Rosenzweig
Molecular MRI detects low levels of cardiomyocyte apoptosis in a transgenic model of chronic heart failure.
Circulation. Cardiovascular imaging 2009;2(6):468-75.
2009: David E Sosnovik; Elisabeth Garanger; Elena Aikawa; Matthias Nahrendorf; Jose-Luiz Figuiredo; Guangping Dai; Fred Reynolds; Anthony Rosenzweig; Ralph Weissleder; Lee Josephson
Molecular MRI of cardiomyocyte apoptosis with simultaneous delayed-enhancement MRI distinguishes apoptotic and necrotic myocytes in vivo: potential for midmyocardial salvage in acute ischemia.
Circulation. Cardiovascular imaging 2009;2(6):460-7.
2009: Elisabeth Garanger; Scott A Hilderbrand; Joe Blois; David E Sosnovik; Ralph Weissleder; Lee Josephson
A DNA-binding Gd chelate for the detection of cell death by MRI.
Chemical communications (Cambridge, England) 2009;(29):4444-6.
2009: David E Sosnovik; Ruopeng Wang; Guangping Dai; Teresa Wang; Elena Aikawa; Mikhael Novikov; Anthony Rosenzweig; Richard J Gilbert; Van J Wedeen
Diffusion spectrum MRI tractography reveals the presence of a complex network of residual myofibers in infarcted myocardium.
Circulation. Cardiovascular imaging 2009;2(3):206-12.
2009: Jose-Luiz Figueiredo; Matthias Nahrendorf; David E Sosnovik; Ralph Weissleder
MRI of a novel murine working heart transplant model.
Circulation. Heart failure 2009;2(3):272-4.
2009: David E Sosnovik
Will molecular MR imaging play a role in identification and treatment of patients with vulnerable atherosclerotic plaques?
Radiology 2009;251(2):309-10.
2009: David E Sosnovik; Ruopeng Wang; Guangping Dai; Timothy G Reese; Van J Wedeen
Diffusion MR tractography of the heart.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 2009;11():47.
2009: Matthias Nahrendorf; David E Sosnovik; Brent A French; Filip K Swirski; Frank M Bengel; Mehran M Sadeghi; Jonathan R Lindner; Joseph C Wu; Dara L Kraitchman; Zahi A Fayad; Albert J Sinusas
Multimodality cardiovascular molecular imaging, Part II.
Circulation. Cardiovascular imaging 2009;2(1):56-70.
2008: Grigorios Korosoglou; Saurabh Shah; Evert-Jan P A Vonken; Wesley D Gilson; Michael Schär; Lijun Tang; Dara L Kraitchman; Raymond C Boston; David E Sosnovik; Robert G Weiss; Ralph Weissleder; Matthias Stuber
Off-resonance angiography: a new method to depict vessels--phantom and rabbit studies.
Radiology 2008;249(2):501-9.
2008: Grigorios Korosoglou; Robert G Weiss; Dorota A Kedziorek; Piotr Walczak; Wesley D Gilson; Michael Schär; David E Sosnovik; Dara L Kraitchman; Raymond C Boston; Jeff W M Bulte; Ralph Weissleder; Matthias Stuber
Noninvasive detection of macrophage-rich atherosclerotic plaque in hyperlipidemic rabbits using "positive contrast" magnetic resonance imaging.
Journal of the American College of Cardiology 2008;52(6):483-91.
2008: David E Sosnovik; Matthias Nahrendorf; Ralph Weissleder
Targeted imaging of myocardial damage.
Nature clinical practice. Cardiovascular medicine 2008;5 Suppl 2():S63-70.
2008: Melanie Schmitt; Andreas Potthast; David E Sosnovik; Jonathan R Polimeni; Graham C Wiggins; Christina Triantafyllou; Lawrence L Wald
A 128-channel receive-only cardiac coil for highly accelerated cardiac MRI at 3 Tesla.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2008;59(6):1431-9.
2008: Ethan Chauncey Korngold; Farouc Amin Jaffer; Ralph Weissleder; David E Sosnovik
Noninvasive imaging of apoptosis in cardiovascular disease.
Heart failure reviews 2008;13(2):163-73.
2008: Christian T Farrar; Guangping Dai; Mikhail Novikov; Anthony Rosenzweig; Ralph Weissleder; Bruce R Rosen; David E Sosnovik
Impact of field strength and iron oxide nanoparticle concentration on the linearity and diagnostic accuracy of off-resonance imaging.
NMR in biomedicine 2008;21(5):453-63.
2008: Grigorios Korosoglou; Lijun Tang; Dorota Kedziorek; Kenyatta Cosby; Wesley D Gilson; Evert-Jan Vonken; Michael Schär; David E Sosnovik; Dara L Kraitchman; Robert G Weiss; Ralf Weissleder; Matthias Stuber
Positive contrast MR-lymphography using inversion recovery with ON-resonant water suppression (IRON).
Journal of magnetic resonance imaging : JMRI 2008;27(5):1175-80.
2008: Matthias Nahrendorf; David E Sosnovik; John W Chen; Peter Panizzi; Jose-Luiz Figueiredo; Elena Aikawa; Peter Libby; Filip K Swirski; Ralph Weissleder
Activatable magnetic resonance imaging agent reports myeloperoxidase activity in healing infarcts and noninvasively detects the antiinflammatory effects of atorvastatin on ischemia-reperfusion injury.
Circulation 2008;117(9):1153-60.
2008: David E Sosnovik; Matthias Nahrendorf; Ralph Weissleder
Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications.
Basic research in cardiology 2008;103(2):122-30.
2008: Matthias Nahrendorf; David E Sosnovik; Ralph Weissleder
MR-optical imaging of cardiovascular molecular targets.
Basic research in cardiology 2008;103(2):87-94.
2008: David E Sosnovik
Molecular imaging in cardiovascular magnetic resonance imaging: current perspective and future potential.
Topics in magnetic resonance imaging : TMRI 2008;19(1):59-68.
2008: Matthias Nahrendorf; Elena Aikawa; Jose-Luiz Figueiredo; Lars Stangenberg; Susanne W van den Borne; W Matthijs Blankesteijn; David E Sosnovik; Farouc A Jaffer; Ching-Hsuan Tung; Ralph Weissleder
Transglutaminase activity in acute infarcts predicts healing outcome and left ventricular remodelling: implications for FXIII therapy and antithrombin use in myocardial infarction.
European heart journal 2008;29(4):445-54.
2008: Matthias Nahrendorf; Hanwen Zhang; Sheena Hembrador; Peter Panizzi; David E Sosnovik; Elena Aikawa; Peter Libby; Filip K Swirski; Ralph Weissleder
Nanoparticle PET-CT imaging of macrophages in inflammatory atherosclerosis.
Circulation 2008;117(3):379-87.
2007: Sonia Taktak; David E Sosnovik; Michael J Cima; Ralph Weissleder; Lee Josephson
Multiparameter magnetic relaxation switch assays.
Analytical chemistry 2007;79(23):8863-9.
2007: David E Sosnovik; Guangping Dai; Matthias Nahrendorf; Bruce R Rosen; Ravi Seethamraju
Cardiac MRI in mice at 9.4 Tesla with a transmit-receive surface coil and a cardiac-tailored intensity-correction algorithm.
Journal of magnetic resonance imaging : JMRI 2007;26(2):279-87.
2007: Matthias Nahrendorf; Cristian T Badea; Laurence W Hedlund; Jose-Luiz Figueiredo; David E Sosnovik; G Allan Johnson; Ralph Weissleder
High-resolution imaging of murine myocardial infarction with delayed-enhancement cine micro-CT.
American journal of physiology. Heart and circulatory physiology 2007;292(6):H3172-8.
2007: Matthias Nahrendorf; David E Sosnovik; Peter Waterman; Filip K Swirski; Ashvin N Pande; Elena Aikawa; Jose-Luiz Figueiredo; Mikaël J Pittet; Ralph Weissleder
Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct.
Circulation research 2007;100(8):1218-25.
2007: David E Sosnovik; Matthias Nahrendorf; Ralph Weissleder
Molecular magnetic resonance imaging in cardiovascular medicine.
Circulation 2007;115(15):2076-86.
2007: David E Sosnovik; Matthias Nahrendorf; Nikolaos Deliolanis; Mikhail Novikov; Elena Aikawa; Lee Josephson; Anthony Rosenzweig; Ralph Weissleder; Vasilis Ntziachristos
Fluorescence tomography and magnetic resonance imaging of myocardial macrophage infiltration in infarcted myocardium in vivo.
Circulation 2007;115(11):1384-91.
2007: Suhny Abbara; Antonio J Pena; Pal Maurovich-Horvat; Javed Butler; David E Sosnovik; Alexander Lembcke; Ricardo Cury; Udo Hoffmann; Maros Ferencik; Thomas J Brady
Feasibility and optimization of aortic valve planimetry with MDCT.
AJR. American journal of roentgenology 2007;188(2):356-60.
2007: David E Sosnovik; Ralph Weissleder
Emerging concepts in molecular MRI.
Current opinion in biotechnology 2007;18(1):4-10.
2007: Elena Aikawa; Matthias Nahrendorf; David E Sosnovik; Vincent M Lok; Farouc A Jaffer; Masanori Aikawa; Ralph Weissleder
Multimodality molecular imaging identifies proteolytic and osteogenic activities in early aortic valve disease.
Circulation 2007;115(3):377-86.
2006: Farouc A Jaffer; David E Sosnovik; Matthias Nahrendorf; Ralph Weissleder
Molecular imaging of myocardial infarction.
Journal of molecular and cellular cardiology 2006;41(6):921-33.
2006: Matthias Nahrendorf; Farouc A Jaffer; Kimberly A Kelly; David E Sosnovik; Elena Aikawa; Peter Libby; Ralph Weissleder
Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis.
Circulation 2006;114(14):1504-11.
2006: Matthias Nahrendorf; Jörg U G Streif; Karl-Heinz Hiller; Kai Hu; Peter Nordbeck; Oliver Ritter; David E Sosnovik; Lisa Bauer; Stefan Neubauer; Peter M Jakob; Georg Ertl; Matthias Spindler; Wolfgang R Bauer
Multimodal functional cardiac MRI in creatine kinase-deficient mice reveals subtle abnormalities in myocardial perfusion and mechanics.
American journal of physiology. Heart and circulatory physiology 2006;290(6):H2516-21.
2006: Farouc A Jaffer; Matthias Nahrendorf; David E Sosnovik; Kimberly A Kelly; Elena Aikawa; Ralph Weissleder
Cellular imaging of inflammation in atherosclerosis using magnetofluorescent nanomaterials.
Molecular imaging 2006;5(2):85-92.
2006: Matthias Nahrendorf; Kai Hu; Stefan Frantz; Farouc A Jaffer; Ching-Hsuan Tung; Karl-Heinz Hiller; Sabine Voll; Peter Nordbeck; David E Sosnovik; Stefan Gattenlöhner; Mikhail Novikov; Gerhard Dickneite; Guy L Reed; Peter M Jakob; Anthony Rosenzweig; Wolfgang R Bauer; Ralph Weissleder; Georg Ertl
Factor XIII deficiency causes cardiac rupture, impairs wound healing, and aggravates cardiac remodeling in mice with myocardial infarction.
Circulation 2006;113(9):1196-202.
2005: David E Sosnovik; Eyk A Schellenberger; Matthias Nahrendorf; Mikhail Novikov; Takashi Matsui; George Dai; Fred Reynolds; luanda grazette; Anthony Rosenzweig; Ralph Weissleder; Lee Josephson
Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2005;54(3):718-24.
2005: Steven L Baldwin; Mark R Holland; David E Sosnovik; James G Miller
Effects of region-of-interest length on estimates of myocardial ultrasonic attenuation and backscatter.
Medical physics 2005;32(2):418-26.
2005: David E Sosnovik; Ralph Weissleder
Magnetic resonance and fluorescence based molecular imaging technologies.
Progress in drug research. Fortschritte der Arzneimittelforschung. Progrès des recherches pharmaceutiques 2005;62():83-115.
2004: Eyk A Schellenberger; David E Sosnovik; Ralph Weissleder; Lee Josephson
Magneto/optical annexin V, a multimodal protein.
Bioconjugate chemistry 2004;15(5):1062-7.
2004: Udo Hoffmann; Ryan Millea; Christian N H Enzweiler; Maros Ferencik; Scott Gulick; James Titus; Stephan Achenbach; Dylan C Kwait; David E Sosnovik; Thomas J Brady
Acute myocardial infarction: contrast-enhanced multi-detector row CT in a porcine model.
Radiology 2004;231(3):697-701.
2004: Moussa Mansour; Godtfred Holmvang; David E Sosnovik; Raymond Q Migrino; Suhny Abbara; Jeremy Ruskin; David Keane
Assessment of pulmonary vein anatomic variability by magnetic resonance imaging: implications for catheter ablation techniques for atrial fibrillation.
Journal of cardiovascular electrophysiology 2004;15(4):387-93.
2004: Suhny Abbara; Raymond Q Migrino; David E Sosnovik; Jeffrey A Leichter; Thomas J Brady; Godtfred Holmvang
Value of fat suppression in the MRI evaluation of suspected arrhythmogenic right ventricular dysplasia.
AJR. American journal of roentgenology 2004;182(3):587-91.
2003: David E Sosnovik; James L Januzzi; Charles C Church; Judith A Mertsch; Andrea L Sears; Robert C Fetterman; Richard C Walovitch; Michael H Picard
Measurement of radial artery contrast intensity to assess cardiac microbubble behavior.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2003;16(12):1267-73.
2002: David E Sosnovik; James E Muller; Sekar Kathiresan; Thomas J Brady
Non-invasive imaging of plaque vulnerability: an important tool for the assessment of agents to stabilise atherosclerotic plaques.
Expert opinion on investigational drugs 2002;11(5):693-704.
2001: David E Sosnovik; Steven L Baldwin; SH Lewis; Mark R Holland; James G Miller
Transmural variation of myocardial attenuation measured with a clinical imager.
Ultrasound in medicine & biology 2001;27(12):1643-50.
2001: David E Sosnovik; Steven L Baldwin; Mark R Holland; James G Miller
Transmural variation of myocardial attenuation and its potential effect on contrast-mediated estimates of regional myocardial perfusion.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2001;14(8):782-8.